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$92+ Cheap flights from Des Moines (DSM) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CMH
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$183
(American Airlines)

One-way from

$92
(American Airlines)

Popular in

September

Cheapest in

March

Average price

$448
From Des Moines to Columbus
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One-way flight from Des Moines to Columbus
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Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Columbus

Cheapest flights from Des Moines to Columbus
Explore the most affordable flight options available from Des Moines to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:42 pmDSM - CMH
1 stop4h 23mAmerican Airlines
Wed 10/296:15 amCMH - DSM
1 stop5h 30mAmerican Airlines
Deal found 9/10$183
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2911:19 amDSM - CMH
1 stop22h 10mMultiple Airlines
Sun 11/26:21 pmCMH - DSM
1 stop15h 13mMultiple Airlines
Deal found 9/9$241
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/222:37 pmDSM - CMH
1 stop26h 32mMultiple Airlines
Wed 10/2912:14 pmCMH - DSM
1 stop26h 47mMultiple Airlines
Deal found 9/8$244
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:31 amDSM - CMH
1 stop4h 17mUnited Airlines
Sat 11/110:36 amCMH - DSM
2 stops11h 09mUnited Airlines
Deal found 9/10$248
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:11 pmDSM - CMH
1 stop4h 48mAmerican Airlines
Sun 10/55:37 amCMH - DSM
1 stop3h 32mAmerican Airlines
Deal found 9/11$250
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1711:31 amDSM - CMH
1 stop5h 45mUnited Airlines
Fri 10/246:02 amCMH - DSM
1 stop5h 30mUnited Airlines
Deal found 9/10$251
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:00 amDSM - CMH
1 stop6h 23mUnited Airlines
Wed 10/2910:26 amCMH - DSM
2 stops11h 19mUnited Airlines
Deal found 9/10$258
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:22 pmDSM - CMH
1 stop4h 37mAmerican Airlines
Mon 10/208:33 pmCMH - DSM
1 stop3h 50mAmerican Airlines
Deal found 9/11$259
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/282:25 pmDSM - CMH
1 stop28h 14mMultiple Airlines
Wed 10/112:14 pmCMH - DSM
1 stop25h 47mMultiple Airlines
Deal found 9/9$263
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:21 amDSM - CMH
1 stop5h 58mDelta
Tue 5/121:35 pmCMH - DSM
1 stop4h 34mDelta
Deal found 9/10$271

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Columbus that are best for you.

Fly from

Des Moines

Fly to

Columbus

Route

Depart

Return

Price

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Wed 10/22

2:37 pm-3:25 pm

2 stops23h 48m

Columbus

Wed 10/29

12:14 pm-2:01 pm

1 stop26h 47m

$244

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 10/2

6:11 pm-11:59 pm

1 stop4h 48m

Columbus

Sun 10/5

5:37 am-8:09 am

1 stop3h 32m

$250

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Wed 10/22

8:00 am-3:23 pm

1 stop6h 23m

Columbus

Wed 10/29

10:26 am-8:45 pm

2 stops11h 19m

$258

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sun 9/28

2:25 pm-7:39 pm

1 stop28h 14m

Columbus

Wed 10/1

12:14 pm-1:01 pm

1 stop25h 47m

$263

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sat 10/25

9:20 am-8:45 pm

2 stops10h 25m

Columbus

Sat 11/1

2:20 pm-11:44 pm

2 stops10h 24m

$263

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 11/27

6:17 am-1:27 pm

1 stop6h 10m

Columbus

Wed 5/13

6:25 am-9:19 am

1 stop3h 54m

$271

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Mon 11/24

11:28 am-5:34 pm

1 stop5h 06m

Columbus

Wed 5/13

1:35 pm-5:09 pm

1 stop4h 34m

$271

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 10/16

6:22 pm-11:47 pm

1 stop4h 25m

Columbus

Sat 10/18

2:21 pm-8:11 pm

1 stop6h 50m

$274

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sat 10/4

6:00 am-11:24 am

1 stop4h 24m

Columbus

Thu 10/9

6:05 am-10:05 am

1 stop5h 00m

$279

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 10/2

10:41 am-8:02 pm

1 stop8h 21m

Columbus

Sun 10/5

11:21 am-5:01 pm

2 stops30h 40m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 20 results
1
2

Best time to book a flight from Des Moines to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Columbus

What is the cheapest month to book a flight from Des Moines to Columbus?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Columbus (average of $254). Flying from Des Moines to Columbus in March is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Columbus to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Columbus?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Columbus. 4 airlines have flights from Des Moines to Columbus on a regular basis. Booking flights from Des Moines to Columbus should not be difficult; the airport handles an average of 0 outbound flights to Columbus per day.

  • How long is the flight from Des Moines to Columbus?

    For as low as $250, American Airlines can have you in Columbus from Des Moines in 4h 48m. Des Moines and Columbus are separated by a distance of 573 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Columbus round-trip?

    Currently priced at $250, American Airlines will fly you from Des Moines to Columbus and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and Delta - these airlines can fly you to your destination from $250 and $250, respectively. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Columbus that include hotel bookings?

    Yes. In addition to deals on Des Moines to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Columbus.

  • Can I find deals for business class flights from Des Moines to Columbus?

    Yes. Cheapflights offers flight deals from Des Moines to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Columbus?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Columbus (average of $254). Flying from Des Moines to Columbus in March is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Des Moines to Columbus

Discover the top 4 airlines that operate flights from Des Moines to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$197Average$379FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$250Average$448FlexibilityNo cancel feeOn-time71%
DeltaCheapest$250Average$402FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$265Average$346FlexibilityNo cancel feeOn-time63%

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