$121+ Cheap flights from Des Moines (DSM) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CMH
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Best
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Cheapest flights from Des Moines to ColumbusExplore the most affordable flight options available from Des Moines to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from Des Moines to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:25 am
DSM
- CMH
1 stop3h 35m
Southwest
Wed 4/158:30 am
CMH
- DSM
1 stop3h 55m
Southwest
Deal found 3/6![Southwest logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:26 am
DSM
- CMH
2 stops24h 16m
Multiple Airlines
Thu 4/211:42 am
CMH
- DSM
1 stop12h 09m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:30 am
DSM
- CMH
2 stops25h 45m
Multiple Airlines
Sun 4/268:19 pm
CMH
- DSM
1 stop17h 50m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:44 am
DSM
- CMH
1 stop5h 37m
American Airlines
Mon 5/188:56 pm
CMH
- DSM
1 stop3h 53m
American Airlines
Deal found 3/10![American Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:33 pm
DSM
- CMH
1 stop6h 00m
Delta
Mon 5/186:44 pm
CMH
- DSM
1 stop4h 48m
Delta
Deal found 3/9![Delta logo]()
$316
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:04 am
DSM
- CMH
1 stop6h 23m
United Airlines
Thu 4/27:00 am
CMH
- DSM
1 stop6h 29m
United Airlines
Deal found 3/7![United Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:25 am
DSM
- CMH
1 stop3h 35m
Southwest
Sun 5/106:50 am
CMH
- DSM
1 stop9h 50m
Southwest
Deal found 3/8![Southwest logo]()
$347
Best flights from Des Moines to ColumbusDiscover carefully curated flight deals from Des Moines to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from Des Moines to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:25 am
DSM
- CMH
1 stop3h 35m
Southwest
Wed 4/158:30 am
CMH
- DSM
1 stop3h 55m
Southwest
Deal found 3/6![Southwest logo]()
$293
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:04 am
DSM
- CMH
1 stop6h 23m
United Airlines
Thu 4/27:00 am
CMH
- DSM
1 stop6h 29m
United Airlines
Deal found 3/7![United Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:25 am
DSM
- CMH
1 stop3h 35m
Southwest
Sun 5/106:50 am
CMH
- DSM
1 stop9h 50m
Southwest
Deal found 3/8![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:20 am
DSM
- CMH
1 stop5h 52m
United Airlines
Wed 4/157:00 am
CMH
- DSM
1 stop4h 44m
United Airlines
Deal found 3/7![United Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:25 am
DSM
- CMH
2 stops6h 15m
Southwest
Mon 4/131:15 pm
CMH
- DSM
2 stops10h 50m
Southwest
Deal found 3/8![Southwest logo]()
$357
Last-minute flights from Des Moines to ColumbusDiscover last-minute flight deals from Des Moines to Columbus. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Columbus. Data last updated March 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:15 am
DSM
- CMH
1 stop12h 04m
Multiple Airlines
Tue 3/241:07 pm
CMH
- DSM
2 stops31h 09m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:26 am
DSM
- CMH
2 stops24h 16m
Multiple Airlines
Thu 4/211:42 am
CMH
- DSM
1 stop12h 09m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:04 am
DSM
- CMH
1 stop6h 23m
United Airlines
Thu 4/27:00 am
CMH
- DSM
1 stop6h 29m
United Airlines
Deal found 3/7![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:25 pm
DSM
- CMH
1 stop6h 32m
Delta
Sun 4/56:06 pm
CMH
- DSM
1 stop3h 39m
Delta
Deal found 3/8![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:25 am
DSM
- CMH
1 stop4h 25m
United Airlines
Sun 4/510:36 am
CMH
- DSM
2 stops8h 39m
United Airlines
Deal found 3/8![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:25 am
DSM
- CMH
1 stop3h 35m
Southwest
Wed 4/158:30 am
CMH
- DSM
1 stop3h 55m
Southwest
Deal found 3/6![Southwest logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:30 am
DSM
- CMH
2 stops25h 45m
Multiple Airlines
Sun 4/268:19 pm
CMH
- DSM
1 stop17h 50m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:20 am
DSM
- CMH
1 stop3h 35m
Southwest
Sun 4/268:20 pm
CMH
- DSM
1 stop4h 00m
Southwest
Deal found 3/10![Southwest logo]()
$367
One-way flights from Des Moines to ColumbusSearch for one-way flight options from Des Moines to Columbus. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from Des Moines to Columbus. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:56 pm
DSM
- CMH
1 stop12h 34m
Frontier
Deal found 3/7![Frontier logo]()
$121
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:06 pm
DSM
- CMH
1 stop5h 58m
American Airlines
Deal found 3/7![American Airlines logo]()
$153
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 am
DSM
- CMH
2 stops6h 00m
Southwest
Deal found 3/7![Southwest logo]()
$158
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:41 pm
DSM
- CMH
1 stop4h 49m
Delta
Deal found 3/9![Delta logo]()
$164
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:25 am
DSM
- CMH
2 stops11h 45m
Southwest
Deal found 3/6![Southwest logo]()
$175
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:20 pm
DSM
- CMH
1 stop7h 19m
American Airlines
Deal found 3/10![American Airlines logo]()
$184
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:25 am
DSM
- CMH
2 stops6h 15m
Southwest
Deal found 3/10![Southwest logo]()
$189
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:35 pm
DSM
- CMH
1 stop4h 20m
Delta
Deal found 3/11![Delta logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:15 am
DSM
- CMH
1 stop24h 15m
Frontier
Deal found 3/10![Frontier logo]()
$200
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:30 am
DSM
- CMH
2 stops8h 58m
United Airlines
Deal found 3/7![United Airlines logo]()
$204
Find flight deals from Des Moines to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.
Round-trip from | $293 (Southwest) |
|---|---|
One-way from | $121 (Expedia) |
Popular in | August |
Cheapest in | June |
Average price | $481 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Des Moines to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Thu 4/9
5:25 am-10:00 am
1 stop3h 35m
Columbus
Wed 4/15
8:30 am-11:25 am
1 stop3h 55m
$293
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Mon 3/30
8:04 am-3:27 pm
1 stop6h 23m
Columbus
Thu 4/2
7:00 am-12:29 pm
1 stop6h 29m
$327
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Thu 5/7
5:25 am-10:00 am
1 stop3h 35m
Columbus
Sun 5/10
6:50 am-3:40 pm
1 stop9h 50m
$347
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Thu 4/9
5:25 am-12:40 pm
2 stops6h 15m
Columbus
Mon 4/13
1:15 pm-11:05 pm
2 stops10h 50m
$357
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Sat 4/11
6:20 am-1:12 pm
1 stop5h 52m
Columbus
Wed 4/15
7:00 am-10:44 am
1 stop4h 44m
$386
Cheapest one-way
Quickest one-way
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Thu 5/14
5:56 pm-11:52 pm
1 stop4h 56m
$164
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Mon 4/20
5:25 am-6:10 pm
2 stops11h 45m
$175
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Fri 5/1
3:20 pm-11:39 pm
1 stop7h 19m
$184
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Sat 6/20
6:20 am-1:27 pm
1 stop6h 07m
$184
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Fri 5/1
5:25 am-12:40 pm
2 stops6h 15m
$189
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from Des Moines with our price prediction graph.
DSM-C01
DSM-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Columbus
DSM-C01
DSM-CMH
What is the cheapest month to book a flight from Des Moines to Columbus?
Currently, June is the cheapest month in which you can book a flight from Des Moines to Columbus (average of $197). Flying from Des Moines to Columbus in January is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated March 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Columbus to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Find flights from Des Moines to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Columbus flights
Browse other Des Moines and Columbus flight options. Last updated on March 11, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Des Moines to Columbus
Discover the top 4 airlines that operate flights from Des Moines to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$197 | Average$364 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$250 | Average$356 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$250 | Average$501 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$341 | FlexibilityNo cancel fee | On-time63% |