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$152+ Cheap flights from Des Moines (DSM) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CMH
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Columbus

Cheapest flights from Des Moines to Columbus
Explore the most affordable flight options available from Des Moines to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:07 pmDSM - CMH
1 stop4h 41mAmerican Airlines
Mon 1/56:36 amCMH - DSM
1 stop7h 45mAmerican Airlines
Deal found 12/11$338
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:46 pmDSM - CMH
1 stop3h 58mUnited Airlines
Sat 1/107:00 amCMH - DSM
1 stop4h 55mUnited Airlines
Deal found 12/11$352
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:14 pmDSM - CMH
1 stop6h 02mUnited Airlines
Mon 1/58:10 amCMH - DSM
2 stops10h 55mUnited Airlines
Deal found 12/11$374
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:15 amDSM - CMH
1 stop4h 00mDelta
Fri 1/26:30 amCMH - DSM
1 stop4h 19mDelta
Deal found 12/11$417
This Southwest deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:15 amDSM - CMH
2 stops9h 10mSouthwest
Mon 1/59:00 pmCMH - DSM
1 stop3h 35mSouthwest
Deal found 12/9$425
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:30 amDSM - CMH
2 stops10h 35mSouthwest
Mon 1/59:00 pmCMH - DSM
1 stop3h 35mSouthwest
Deal found 12/11$438
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 pmDSM - CMH
1 stop4h 43mDelta
Tue 12/306:00 amCMH - DSM
1 stop5h 38mDelta
Deal found 12/10$447

Find flight deals from Des Moines to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Round-trip from

$295
(Delta)

One-way from

$152
(Mytrip)

Popular in

August

Cheapest in

March

Average price

$423
From Des Moines to Columbus
Search Deals
One-way flight from Des Moines to Columbus
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Columbus that are best for you.

Fly from

Des Moines

Fly to

Columbus

Route

Depart

Return

Price

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Fri 1/16

5:16 pm-12:01 am

1 stop5h 45m

Columbus

Sun 1/18

8:15 am-11:24 am

1 stop4h 09m

$295

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 1/1

6:46 pm-11:44 pm

1 stop3h 58m

Columbus

Sun 1/4

7:00 am-10:49 am

1 stop4h 49m

$305

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Wed 2/18

3:24 pm-10:05 pm

1 stop5h 41m

Columbus

Sat 2/21

7:09 am-10:53 am

1 stop4h 44m

$310

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sun 1/25

4:30 pm-11:27 pm

2 stops29h 57m

Columbus

Sun 2/1

6:54 pm-9:21 pm

1 stop27h 27m

$312

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 1/8

6:10 am-1:00 pm

2 stops5h 50m

Columbus

Thu 1/15

5:45 am-10:50 am

2 stops6h 05m

$335

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Wed 12/31

2:07 pm-7:48 pm

1 stop4h 41m

Columbus

Mon 1/5

6:36 am-1:21 pm

1 stop7h 45m

$338

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Fri 2/20

5:39 pm-12:01 am

1 stop5h 22m

Columbus

Mon 2/23

6:03 pm-8:49 pm

1 stop3h 46m

$346

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sun 1/25

2:58 pm-9:40 am

1 stop17h 42m

$152

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Tue 12/30

11:14 am-8:18 pm

1 stop8h 04m

$161

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Mon 12/29

6:40 am-2:35 pm

1 stop6h 55m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 12 results
1
2

Best time to book a flight from Des Moines to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Columbus

What is the cheapest month to book a flight from Des Moines to Columbus?

Currently, July is the cheapest month in which you can book a flight from Des Moines to Columbus (average of $247). Flying from Des Moines to Columbus in February is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Columbus?

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Columbus to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Columbus?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Columbus. 4 airlines have flights from Des Moines to Columbus on a regular basis. Booking flights from Des Moines to Columbus should not be difficult; the airport handles an average of 0 outbound flights to Columbus per day.

  • How long is the flight from Des Moines to Columbus?

    For as low as $305, Delta can have you in Columbus from Des Moines in 3h 58m. Des Moines and Columbus are separated by a distance of 573 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Columbus round-trip?

    Currently priced at $248, Delta will fly you from Des Moines to Columbus and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $250 and $250, respectively. These flights start at 36% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Columbus one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $118. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from Des Moines to Columbus for a low price.

  • Can I find deals for flights from Des Moines to Columbus that include hotel bookings?

    Yes. In addition to deals on Des Moines to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Columbus.

  • Can I find deals for business class flights from Des Moines to Columbus?

    Yes. Cheapflights offers flight deals from Des Moines to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Columbus?

    Currently, July is the cheapest month in which you can book a flight from Des Moines to Columbus (average of $247). Flying from Des Moines to Columbus in February is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Des Moines to Columbus

Discover the top 4 airlines that operate flights from Des Moines to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$197Average$401FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$481FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$356FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$260Average$341FlexibilityNo cancel feeOn-time63%

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