$249+ Cheap flights from Des Moines (DSM) to Cabo San Lucas, Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJD
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Cabo San Lucas with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Cabo San Lucas
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Best
Last-minute
One-way
Cheapest flights from Des Moines to Cabo San LucasExplore the most affordable flight options available from Des Moines to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Des Moines to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:42 pm -
1 stop16h 10m
Fri 10/162:27 pm -
1 stop16h 48m
Deal found 9/4![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:05 am -
1 stop8h 09m
Fri 12/113:51 pm -
2 stops16h 24m
Deal found 9/5![American Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:12 pm -
1 stop24h 10m
Tue 10/131:17 pm -
2 stops17h 58m
Deal found 9/3![American Airlines logo]()
$601
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:45 pm -
2 stops17h 58m
Tue 12/112:49 pm -
1 stop8h 32m
Deal found 9/4![United Airlines logo]()
$605
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am -
1 stop7h 22m
Fri 10/26:15 am -
2 stops14h 11m
Deal found 9/8![Delta logo]()
$617
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:22 pm -
2 stops20h 02m
Fri 10/212:26 pm -
1 stop8h 46m
Deal found 9/4![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:05 am -
1 stop6h 57m
Thu 1/282:14 pm -
1 stop6h 56m
Deal found 9/5![American Airlines logo]()
$622
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:45 am -
1 stop6h 50m
Sat 11/73:26 pm -
1 stop16h 41m
Deal found 9/6![American Airlines logo]()
$632
Best flights from Des Moines to Cabo San LucasDiscover carefully curated flight deals from Des Moines to Cabo San Lucas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Des Moines to Cabo San Lucas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/316:25 am -
1 stop7h 15m
Sun 2/71:35 pm -
1 stop6h 45m
Deal found 9/3![Southwest logo]()
$623
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
1 stop7h 32m
Thu 12/1012:49 pm -
1 stop8h 32m
Deal found 9/4![United Airlines logo]()
$713
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:55 pm -
2 stops17h 35m
Fri 10/1611:32 am -
2 stops20h 59m
Deal found 9/6![United Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/168:00 am -
3 stops28h 43m
Mon 2/223:46 pm -
1 stop27h 46m
Deal found 9/4![United Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:27 pm -
1 stop24h 38m
Thu 10/81:17 pm -
1 stop8h 31m
Deal found 9/7![United Airlines logo]()
$788
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/188:00 am -
2 stops28h 43m
Mon 2/223:46 pm -
1 stop27h 46m
Deal found 9/4![United Airlines logo]()
$789
Last-minute flights from Des Moines to Cabo San LucasDiscover last-minute flight deals from Des Moines to Cabo San Lucas. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Cabo San Lucas. Data last updated September 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am -
1 stop7h 22m
Fri 10/26:15 am -
2 stops14h 11m
Deal found 9/8![Delta logo]()
$617
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:22 pm -
2 stops20h 02m
Fri 10/212:26 pm -
1 stop8h 46m
Deal found 9/4![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:22 pm -
2 stops20h 02m
Mon 10/511:57 am -
2 stops9h 10m
Deal found 9/4![American Airlines logo]()
$660
This Aeromexico deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am -
1 stop7h 22m
Fri 10/212:12 pm -
1 stop8h 14m
Deal found 9/8![Aeromexico logo]()
$676
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:12 pm -
1 stop24h 10m
Tue 10/131:17 pm -
2 stops17h 58m
Deal found 9/3![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:42 pm -
1 stop16h 10m
Fri 10/162:27 pm -
1 stop16h 48m
Deal found 9/4![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:06 am -
1 stop7h 51m
Mon 10/263:22 pm -
1 stop15h 53m
Deal found 9/4![American Airlines logo]()
$656
One-way flights from Des Moines to Cabo San LucasSearch for one-way flight options from Des Moines to Cabo San Lucas. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Des Moines to Cabo San Lucas. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:46 pm -
1 stop17h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:15 pm -
1 stop17h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:05 am -
2 stops8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Southwest logo]()
$305
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:20 am -
2 stops10h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/68:00 am -
3 stops28h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$341
This Aeromexico deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/105:45 am -
2 stops17h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Aeromexico logo]()
$346
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:16 pm -
1 stop17h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$406
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/102:59 pm -
3 stops44h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$430
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:12 pm -
2 stops19h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$533
Find flight deals from Des Moines to Cabo San Lucas
Keep the following information in mind while searching for Des Moines to Cabo San Lucas flight deals. Data was last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $587 (American Airlines) |
One-way from | $249 (American Airlines) |
Popular in | May |
Cheapest in | April |
Average price | $592 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Cabo San Lucas that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Des Moines to Cabo San Lucas that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sat 2/6
7:46 pm-11:58 am
1 stop17h 12m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$275
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sat 11/28
7:15 pm-11:58 am
1 stop17h 43m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$292
Quickest round-trip
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sat 2/6
7:05 am-2:55 pm
2 stops8h 50m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$305
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sat 11/28
5:20 am-3:00 pm
2 stops10h 40m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$326
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sat 2/6
8:00 am-11:43 am
3 stops28h 43m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$341
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Wed 2/10
5:45 am-10:30 pm
2 stops17h 45m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$346
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sun 1/31
6:25 am-12:40 pm
1 stop7h 15m
San José del Cabo Los Cabos
Sun 2/7
1:35 pm-9:20 pm
1 stop6h 45m
$623
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Mon 12/7
8:00 am-2:32 pm
1 stop7h 32m
San José del Cabo Los Cabos
Thu 12/10
12:49 pm-10:21 pm
1 stop8h 32m
$713
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Sun 10/11
6:55 pm-10:30 am
2 stops17h 35m
San José del Cabo Los Cabos
Fri 10/16
11:32 am-10:31 am
2 stops20h 59m
$741
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Tue 2/16
8:00 am-11:43 am
3 stops28h 43m
San José del Cabo Los Cabos
Mon 2/22
3:46 pm-8:32 pm
1 stop27h 46m
$759
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Cabo San Lucas
Have a flexible travel schedule? Discover the best time to fly to Cabo San Lucas from Des Moines with our price prediction graph.
DSM-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Cabo San Lucas
DSM-C4B
DSM-SJD
How much does it cost to fly round-trip from Des Moines to Cabo San Lucas?
Airfare is below average for this route at the moment.
Des Moines to Cabo San Lucas flights typically cost between $592 and $642 in October.The cheapest round-trip price found within the last 5 days was $587 on American Airlines (Oct 11-Oct 16).
Reviews of airlines servicing Cabo San Lucas
Get insights into the airlines that provide service to Cabo San Lucas. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cabo San Lucas. Reviews last updated September 9, 2026.
Read through reviews of airlines operating flights from Des Moines to Cabo San Lucas, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.7
Entertainment
7.1
Comfort
7.3
Boarding
7.7
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.7
Entertainment
7.1
Comfort
7.3
Boarding
7.7
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.7
Entertainment
7.1
Comfort
7.3
Boarding
7.7
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Cabo San Lucas. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Cabo San Lucas flights
Browse other Des Moines and Cabo San Lucas flight options. Last updated on September 9, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
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Des Moines to Cabo San Lucas flights
Consider these flights traveling from Des Moines to Cabo San Lucas.
Top 2 airlines flying from Des Moines to Cabo San Lucas
Discover the top 2 airlines that operate flights from Des Moines to Cabo San Lucas. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$459 | Average$663 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$462 | Average$713 | FlexibilityNo cancel fee | On-time71% |