HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cabo San Lucas

$230+ Cheap flights from Des Moines (DSM) to Cabo San Lucas, Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJD
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Cabo San Lucas with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Cabo San Lucas

Cheapest flights from Des Moines to Cabo San Lucas
Explore the most affordable flight options available from Des Moines to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:26 pm
DSM
-
SJD
1 stop20h 20m
American Airlines
Sat 5/1610:35 am
SJD
-
DSM
1 stop11h 24m
American Airlines
Deal found 3/26$419
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:56 pm
DSM
-
SJD
1 stop17h 36m
American Airlines
Tue 5/192:59 pm
SJD
-
DSM
1 stop6h 17m
American Airlines
Deal found 3/27$427
This lastminute.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:57 am
DSM
-
SJD
2 stops12h 31m
Aeromexico
Tue 5/196:07 am
SJD
-
DSM
2 stops14h 25m
Aeromexico
Deal found 3/28$437
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:00 am
DSM
-
SJD
1 stop6h 35m
American Airlines
Tue 5/122:59 pm
SJD
-
DSM
1 stop6h 17m
American Airlines
Deal found 3/26$477
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:05 pm
DSM
-
SJD
1 stop16h 30m
American Airlines
Thu 4/3011:31 am
SJD
-
DSM
1 stop10h 28m
American Airlines
Deal found 3/28$492
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:27 am
DSM
-
SJD
2 stops14h 21m
Delta
Tue 5/126:07 am
SJD
-
DSM
2 stops14h 25m
Delta
Deal found 3/26$498
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:06 pm
DSM
-
SJD
1 stop18h 07m
American Airlines
Sat 5/3011:38 am
SJD
-
DSM
1 stop10h 39m
American Airlines
Deal found 3/26$527

Find flight deals from Des Moines to Cabo San Lucas

Keep the following information in mind while searching for Des Moines to Cabo San Lucas flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$419
(American Airlines)

One-way from

$230
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$513
Provider with most accurate pricing for Des Moines-San José del Cabo Los Cabos flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-San José del Cabo Los Cabos flights.
Search Deals
From Des Moines to Cabo San Lucas
Search Deals
One-way flight from Des Moines to Cabo San Lucas
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Cabo San Lucas that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Des Moines to Cabo San Lucas that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Fri 5/8

5:00 am-9:35 am

1 stop6h 35m

San José del Cabo Los Cabos

Tue 5/12

2:59 pm-11:16 pm

1 stop6h 17m

$477

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 4/21

5:30 am-1:43 pm

1 stop10h 13m

San José del Cabo Los Cabos

Wed 4/22

1:44 pm-10:43 pm

1 stop6h 59m

$560

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Sat 5/23

1:35 pm-8:52 am

2 stops21h 17m

San José del Cabo Los Cabos

Sat 5/30

1:44 pm-10:22 am

2 stops18h 38m

$592

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 5/12

6:55 am-1:25 pm

2 stops8h 30m

San José del Cabo Los Cabos

Tue 5/19

11:45 am-9:15 pm

1 stop7h 30m

$593

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 5/12

7:05 pm-10:30 am

2 stops17h 25m

San José del Cabo Los Cabos

Tue 5/19

1:44 pm-10:37 am

2 stops18h 53m

$599

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Sun 4/26

8:20 am-12:48 pm

1 stop6h 28m

San José del Cabo Los Cabos

Thu 4/30

1:44 pm-9:23 am

2 stops17h 39m

$617
Cheapest one-way

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Thu 5/28

7:06 pm-11:13 am

1 stop18h 07m

$230

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Thu 5/28

8:15 pm-10:30 am

2 stops16h 15m

$236
Quickest one-way

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 4/13

5:45 am-5:49 pm

2 stops14h 04m

$345

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Thu 5/28

4:41 pm-7:10 pm

3 stops28h 29m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Sorted by cheapest first

Best time to book a flight from Des Moines to Cabo San Lucas

Have a flexible travel schedule? Discover the best time to fly to Cabo San Lucas from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Cabo San Lucas

How far ahead should I book a flight from Des Moines to Cabo San Lucas?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Cabo San Lucas. Price data was last updated on March 13, 2026.

To ensure you get the cheapest price possible for a flight from Des Moines to Cabo San Lucas, you should look to book at least 2 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Cabo San Lucas?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Cabo San Lucas (average of $351). Flying from Des Moines to Cabo San Lucas in December is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Cabo San Lucas?

Reviews of airlines servicing Cabo San Lucas

Get insights into the airlines that provide service to Cabo San Lucas. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cabo San Lucas. Reviews last updated April 1, 2026.
Read through reviews of airlines operating flights from Des Moines to Cabo San Lucas, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,529 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,529 reviews
United Airlines
7.4
Good
9,529 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,544 reviews
United Airlines
7.4
Good
9,529 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Cabo San Lucas. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Cabo San Lucas?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Cabo San Lucas. 2 airlines have flights from Des Moines to Cabo San Lucas on a regular basis. Booking flights from Des Moines to Cabo San Lucas should not be difficult; the airport handles an average of 0 outbound flights to Cabo San Lucas per day.

  • How long is the flight from Des Moines to Cabo San Lucas?

    Departing from Des Moines to Cabo San Lucas will take you 6h 35m. The distance from Des Moines to Cabo San Lucas is about 1572 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Cabo San Lucas that include hotel bookings?

    Yes. In addition to deals on Des Moines to Cabo San Lucas flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Cabo San Lucas?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Cabo San Lucas.

  • Can I find deals for business class flights from Des Moines to Cabo San Lucas?

    Yes. Cheapflights offers flight deals from Des Moines to Cabo San Lucas by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Cabo San Lucas?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Cabo San Lucas (average of $351). Flying from Des Moines to Cabo San Lucas in December is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Cabo San Lucas

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to San José del Cabo flights
Sioux City to San José del Cabo flights

Top 2 airlines flying from Des Moines to Cabo San Lucas

Discover the top 2 airlines that operate flights from Des Moines to Cabo San Lucas. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$366Average$597FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$423Average$640FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.