$542+ Cheap flights from Des Moines (DSM) to Cabo San Lucas, Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJD
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Cabo San Lucas
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Cheapest flights from Des Moines to Cabo San LucasExplore the most affordable flight options available from Des Moines to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Des Moines to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:41 am
DSM
- SJD
1 stop8h 30m
American Airlines
Fri 10/210:51 am
SJD
- DSM
1 stop10h 21m
American Airlines
Deal found 7/26![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:52 pm
DSM
- SJD
1 stop17h 49m
American Airlines
Tue 10/1312:41 pm
SJD
- DSM
1 stop9h 23m
American Airlines
Deal found 7/27![American Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:41 am
DSM
- SJD
1 stop8h 30m
American Airlines
Mon 10/53:22 pm
SJD
- DSM
1 stop15h 53m
American Airlines
Deal found 7/26![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:22 pm
DSM
- SJD
2 stops19h 55m
American Airlines
Wed 9/161:19 pm
SJD
- DSM
2 stops17h 58m
American Airlines
Deal found 7/26![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:41 am
DSM
- SJD
1 stop8h 30m
American Airlines
Fri 10/912:41 pm
SJD
- DSM
1 stop18h 13m
American Airlines
Deal found 7/27![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/114:12 pm
DSM
- SJD
1 stop19h 40m
American Airlines
Fri 10/163:16 pm
SJD
- DSM
2 stops15h 59m
American Airlines
Deal found 7/26![American Airlines logo]()
$610
Best flights from Des Moines to Cabo San LucasDiscover carefully curated flight deals from Des Moines to Cabo San Lucas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Des Moines to Cabo San Lucas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:41 am
DSM
- SJD
1 stop8h 30m
American Airlines
Fri 10/210:51 am
SJD
- DSM
1 stop10h 21m
American Airlines
Deal found 7/25![American Airlines logo]()
$542
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:15 am
DSM
- SJD
1 stop8h 33m
United Airlines
Wed 9/161:44 pm
SJD
- DSM
1 stop6h 46m
United Airlines
Deal found 7/27![United Airlines logo]()
$542
This Aeromexico deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:55 am
DSM
- SJD
2 stops17h 35m
Aeromexico
Fri 8/286:15 am
SJD
- DSM
2 stops14h 22m
Aeromexico
Deal found 7/26![Aeromexico logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:42 pm
DSM
- SJD
1 stop16h 10m
American Airlines
Fri 10/162:27 pm
SJD
- DSM
1 stop16h 48m
American Airlines
Deal found 7/28![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:30 am
DSM
- SJD
1 stop7h 17m
American Airlines
Thu 8/2711:47 am
SJD
- DSM
2 stops9h 43m
American Airlines
Deal found 7/26![American Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
DSM
- SJD
1 stop7h 25m
United Airlines
Sat 9/1211:52 am
SJD
- DSM
1 stop9h 03m
United Airlines
Deal found 7/24![United Airlines logo]()
$663
This Aeromexico deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:40 am
DSM
- SJD
2 stops18h 47m
Aeromexico
Fri 10/166:15 am
SJD
- DSM
2 stops14h 19m
Aeromexico
Deal found 7/24![Aeromexico logo]()
$675
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:55 pm
DSM
- SJD
2 stops19h 53m
United Airlines
Tue 10/131:44 pm
SJD
- DSM
2 stops24h 36m
United Airlines
Deal found 7/27![United Airlines logo]()
$666
Last-minute flights from Des Moines to Cabo San LucasDiscover last-minute flight deals from Des Moines to Cabo San Lucas. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Cabo San Lucas. Data last updated July 28, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:37 am
DSM
- SJD
1 stop8h 40m
American Airlines
Fri 7/318:54 am
SJD
- DSM
1 stop13h 05m
American Airlines
Deal found 7/25![American Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/14:48 pm
DSM
- SJD
2 stops17h 13m
American Airlines
Fri 8/71:13 pm
SJD
- DSM
2 stops17h 48m
American Airlines
Deal found 7/26![American Airlines logo]()
$738
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:43 pm
DSM
- SJD
1 stop16h 21m
American Airlines
Mon 8/311:59 am
SJD
- DSM
1 stop9h 40m
American Airlines
Deal found 7/28![American Airlines logo]()
$793
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:33 am
DSM
- SJD
1 stop8h 49m
American Airlines
Thu 8/272:24 pm
SJD
- DSM
1 stop16h 37m
American Airlines
Deal found 7/27![American Airlines logo]()
$542
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 am
DSM
- SJD
3 stops28h 30m
United Airlines
Thu 8/271:44 pm
SJD
- DSM
2 stops18h 42m
United Airlines
Deal found 7/26![United Airlines logo]()
$676
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:33 am
DSM
- SJD
1 stop8h 52m
American Airlines
Sun 8/3011:47 am
SJD
- DSM
1 stop10h 10m
American Airlines
Deal found 7/26![American Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:00 am
DSM
- SJD
3 stops28h 30m
United Airlines
Sun 8/301:44 pm
SJD
- DSM
2 stops19h 08m
United Airlines
Deal found 7/26![United Airlines logo]()
$766
One-way flights from Des Moines to Cabo San LucasSearch for one-way flight options from Des Moines to Cabo San Lucas. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Des Moines to Cabo San Lucas. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:45 pm
DSM
- SJD
2 stops20h 47m
United Airlines
Deal found 7/27![United Airlines logo]()
$638
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:20 pm
DSM
- SJD
1 stop21h 14m
American Airlines
Deal found 7/27![American Airlines logo]()
$673
Find flight deals from Des Moines to Cabo San Lucas
Keep the following information in mind while searching for Des Moines to Cabo San Lucas flight deals. Data was last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $542 (American Airlines) |
Popular in | May |
Cheapest in | April |
Average price | $674 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Cabo San Lucas that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Des Moines to Cabo San Lucas that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Tue 9/29
6:41 am-1:11 pm
1 stop8h 30m
San José del Cabo Los Cabos
Fri 10/2
10:51 am-11:12 pm
1 stop10h 21m
$542
Quickest round-trip
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Wed 9/9
6:15 am-12:48 pm
1 stop8h 33m
San José del Cabo Los Cabos
Wed 9/16
1:44 pm-10:30 pm
1 stop6h 46m
$542
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Tue 8/25
6:55 am-10:30 pm
2 stops17h 35m
San José del Cabo Los Cabos
Fri 8/28
6:15 am-10:37 pm
2 stops14h 22m
$542
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sun 10/11
7:42 pm-9:52 am
1 stop16h 10m
San José del Cabo Los Cabos
Fri 10/16
2:27 pm-9:15 am
1 stop16h 48m
$542
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Mon 8/24
5:30 am-10:47 am
1 stop7h 17m
San José del Cabo Los Cabos
Thu 8/27
11:47 am-11:30 pm
2 stops9h 43m
$546
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sat 9/5
6:00 am-11:25 am
1 stop7h 25m
San José del Cabo Los Cabos
Sat 9/12
11:52 am-10:55 pm
1 stop9h 03m
$663
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sat 10/10
6:55 pm-12:48 pm
2 stops19h 53m
San José del Cabo Los Cabos
Tue 10/13
1:44 pm-4:20 pm
2 stops24h 36m
$666
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sun 10/11
5:40 am-10:27 pm
2 stops18h 47m
San José del Cabo Los Cabos
Fri 10/16
6:15 am-10:34 pm
2 stops14h 19m
$675
Cheapest one-way
Quickest one-way
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sun 12/27
6:45 pm-2:32 pm
2 stops20h 47m
$638
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sun 12/27
6:20 pm-2:34 pm
1 stop21h 14m
$673
Sorted by cheapest first
Best time to book a flight from Des Moines to Cabo San Lucas
Have a flexible travel schedule? Discover the best time to fly to Cabo San Lucas from Des Moines with our price prediction graph.
DSM-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Cabo San Lucas
DSM-C4B
DSM-SJD
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cabo San Lucas
Get insights into the airlines that provide service to Cabo San Lucas. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cabo San Lucas. Reviews last updated July 28, 2026.
Read through reviews of airlines operating flights from Des Moines to Cabo San Lucas, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Food
6.6
Comfort
7.3
Crew
8.1
Overall
7.4
Boarding
7.7
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Entertainment
7.1
Food
6.6
Comfort
7.3
Crew
8.1
Overall
7.4
Boarding
7.7
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Entertainment
7.1
Food
6.6
Comfort
7.3
Crew
8.1
Overall
7.4
Boarding
7.7
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Cabo San Lucas. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Cabo San Lucas by adding a car rental and/or hotel reservation to your travel itinerary.
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Des Moines and Cabo San Lucas flights
Browse other Des Moines and Cabo San Lucas flight options. Last updated on July 28, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Popular flight searches
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Des Moines to Cabo San Lucas flights
Consider these flights traveling from Des Moines to Cabo San Lucas.
Top 2 airlines flying from Des Moines to Cabo San Lucas
Discover the top 2 airlines that operate flights from Des Moines to Cabo San Lucas. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$423 | Average$667 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$441 | Average$685 | FlexibilityNo cancel fee | On-time71% |