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$113+ Cheap flights from Knoxville (TYS) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:23 pmTYS - CMH
1 stop4h 21mUnited Airlines
Sun 1/46:05 amCMH - TYS
1 stop4h 51mUnited Airlines
Deal found 12/16$315
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:44 pmTYS - CMH
2 stops26h 34mMultiple Airlines
Sun 1/49:13 pmCMH - TYS
1 stop13h 02mMultiple Airlines
Deal found 12/16$375
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:59 pmTYS - CMH
1 stop5h 14mDelta
Sat 1/172:16 pmCMH - TYS
1 stop5h 08mDelta
Deal found 12/17$399
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:00 amTYS - CMH
2 stops6h 50mAmerican Airlines
Sat 1/174:13 pmCMH - TYS
1 stop4h 43mAmerican Airlines
Deal found 12/16$467
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:42 amTYS - CMH
1 stop6h 27mAmerican Airlines
Tue 12/305:00 amCMH - TYS
1 stop4h 27mAmerican Airlines
Deal found 12/16$502
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:21 pmTYS - CMH
1 stop4h 57mAmerican Airlines
Tue 12/239:59 amCMH - TYS
1 stop5h 52mAmerican Airlines
Deal found 12/16$527
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:10 amTYS - CMH
1 stop5h 40mDelta
Sun 12/216:00 amCMH - TYS
1 stop3h 17mDelta
Deal found 12/17$547
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:45 amTYS - CMH
2 stops12h 15mUnited Airlines
Sat 12/205:45 pmCMH - TYS
1 stop4h 54mUnited Airlines
Deal found 12/17$552

Find flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Round-trip from

$237
(Delta)

One-way from

$113
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$539
From Knoxville McGhee Tyson to Columbus
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One-way flight from Knoxville McGhee Tyson to Columbus
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Highest demand for flights based on searches. 16% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.

Fly from

Knoxville

Fly to

Columbus

Route

Depart

Return

Price

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 1/13

1:00 pm-5:15 pm

1 stop4h 15m

Columbus

Tue 1/20

7:00 am-11:08 am

1 stop4h 08m

$237

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 2/27

12:55 pm-11:53 pm

1 stop10h 58m

Columbus

Sun 3/1

9:42 am-9:18 pm

1 stop11h 36m

$288

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 1/7

1:00 pm-5:15 pm

1 stop4h 15m

Columbus

Fri 1/9

6:25 am-12:13 pm

1 stop5h 48m

$304

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

7:00 am-1:14 pm

1 stop6h 14m

Columbus

Mon 4/13

4:05 pm-8:46 pm

1 stop4h 41m

$312

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 5/15

7:20 pm-11:58 pm

1 stop4h 38m

Columbus

Tue 5/19

9:55 am-3:06 pm

1 stop5h 11m

$312

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 5/14

7:20 pm-11:58 pm

1 stop4h 38m

Columbus

Tue 5/19

6:00 am-9:11 am

1 stop3h 11m

$312

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 12/31

7:23 pm-11:44 pm

1 stop4h 21m

Columbus

Sun 1/4

6:05 am-10:56 am

1 stop4h 51m

$315

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 1/1

7:23 pm-11:44 pm

1 stop4h 21m

Columbus

Mon 1/5

6:05 am-10:56 am

1 stop4h 51m

$315

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

8:15 am-6:20 pm

2 stops10h 05m

Columbus

Mon 4/13

5:50 am-2:10 pm

1 stop8h 20m

$317

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 2/27

7:30 am-1:31 pm

1 stop6h 01m

Columbus

Sun 3/1

6:35 pm-11:52 pm

1 stop5h 17m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 17 results
1
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Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus

What is the cheapest month to book a flight from Knoxville to Columbus?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CMH?

Find hourly flight availability from Knoxville to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from Knoxville to Columbus at noon. Doing so could potentially save you 46% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Columbus. You should not have trouble finding flights to Columbus from McGhee Tyson; the airport handles an average of 0 outbound flights to Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Columbus. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Columbus?

    For as low as $237, Delta can have you in Columbus from Knoxville in 4h 15m. Airlines will cover a distance of 296 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Columbus round-trip?

    Delta, at $218, was found to be the cheapest airline from Knoxville to Columbus.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Delta is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Columbus?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Columbus

Discover the top 3 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$223Average$268FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$539FlexibilityNo cancel feeOn-time69%

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