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$126+ Cheap flights from Knoxville (TYS) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Dec 21 — Dec 281
Sun 12/21
Sun 12/28
1 adult, Economy
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Find flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2025.

This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:59 pmTYS - CMH
1 stop5h 14mDelta
Sat 1/178:00 amCMH - TYS
1 stop5h 50mDelta
Deal found 11/20$284
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:30 amTYS - CMH
1 stop10h 19mMultiple Airlines
Sun 12/147:44 pmCMH - TYS
1 stop26h 28mMultiple Airlines
Deal found 11/20$285
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:30 amTYS - CMH
1 stop9h 10mMultiple Airlines
Sun 12/711:14 amCMH - TYS
1 stop10h 30mMultiple Airlines
Deal found 11/19$287
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:30 amTYS - CMH
1 stop11h 08mMultiple Airlines
Fri 12/512:56 pmCMH - TYS
2 stops23h 07mMultiple Airlines
Deal found 11/20$293
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:23 amTYS - CMH
1 stop12h 51mMultiple Airlines
Tue 12/911:14 amCMH - TYS
3 stops24h 49mMultiple Airlines
Deal found 11/20$294
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:30 pmTYS - CMH
1 stop4h 23mUnited Airlines
Wed 12/106:00 amCMH - TYS
1 stop4h 13mUnited Airlines
Deal found 11/20$311
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:45 amTYS - CMH
1 stop4h 04mUnited Airlines
Mon 12/296:05 amCMH - TYS
1 stop4h 51mUnited Airlines
Deal found 11/21$317
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:53 pmTYS - CMH
2 stops21h 26mMultiple Airlines
Sun 12/78:33 pmCMH - TYS
1 stop12h 00mMultiple Airlines
Deal found 11/19$327

Cheap flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 21, 2025.

Round-trip from

$284
(Delta)

One-way from

$126
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$446
From Knoxville McGhee Tyson to Columbus
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One-way flight from Knoxville McGhee Tyson to Columbus
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Highest demand for flights based on searches. 15% potential increase in price ($63 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.

Fly from

Knoxville

Fly to

Columbus

Route

Depart

Return

Price

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 12/20

5:40 pm-12:35 am

1 stop6h 55m

Columbus

Sat 1/17

9:04 am-3:56 pm

1 stop6h 52m

$284

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 12/20

6:59 pm-12:13 am

1 stop5h 14m

Columbus

Sat 1/17

8:00 am-1:50 pm

1 stop5h 50m

$284

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 12/4

8:30 am-5:40 pm

1 stop9h 10m

Columbus

Sun 12/7

11:14 am-9:44 pm

1 stop10h 30m

$287

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 12/4

8:30 am-7:38 pm

1 stop11h 08m

Columbus

Fri 12/5

12:56 pm-12:03 pm

2 stops23h 07m

$293

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 12/6

2:30 pm-6:53 pm

1 stop4h 23m

Columbus

Wed 12/10

6:00 am-10:13 am

1 stop4h 13m

$311

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 1/30

5:40 am-11:44 am

1 stop6h 04m

Columbus

Mon 2/2

8:15 am-12:13 pm

1 stop3h 58m

$317

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 12/3

12:53 pm-10:19 am

2 stops21h 26m

Columbus

Sun 12/7

8:33 pm-8:33 am

1 stop12h 00m

$327

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 12/5

9:40 am-2:08 pm

1 stop4h 28m

Columbus

Tue 12/9

6:00 am-10:13 am

1 stop4h 13m

$329

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 12/3

12:50 pm-5:12 pm

1 stop4h 22m

Columbus

Sun 12/7

7:00 am-10:46 am

1 stop3h 46m

$329

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 12/9

7:39 am-1:26 pm

1 stop5h 47m

$126

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 20 results
1
2

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus

What is the cheapest month to book a flight from Knoxville to Columbus?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in November is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CMH?

Find hourly flight availability from Knoxville to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2025.

It’s typically best to fly out from Knoxville to Columbus at noon. Doing so could potentially save you 46% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated November 21, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,029 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Columbus. You should not have trouble finding flights to Columbus from McGhee Tyson; the airport handles an average of 0 outbound flights to Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Columbus. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Columbus?

    For as low as $311, American Airlines can have you in Columbus from Knoxville in 4h 23m. Airlines will cover a distance of 296 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Columbus round-trip?

    Delta, at $218, was found to be the cheapest airline from Knoxville to Columbus.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Delta is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Knoxville to Columbus one-way?

    The cheapest airlines for a one-way flight from Knoxville to Columbus are Delta ($126), United Airlines ($126), and American Airlines ($154).

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Columbus?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in November is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Columbus

Discover the top 3 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$223Average$293FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$539FlexibilityNo cancel feeOn-time69%

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