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$129+ Cheap flights from Knoxville (TYS) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Apr 23 — Apr 301
Thu 4/23
Thu 4/30
1 adult, Economy
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Cheap flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:35 pm
TYS
-
CMH
1 stop6h 57m
Multiple Airlines
Sun 4/267:00 pm
CMH
-
TYS
2 stops22h 30m
Multiple Airlines
Deal found 3/22$252
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:25 pm
TYS
-
CMH
2 stops26h 53m
Multiple Airlines
Sun 4/126:40 pm
CMH
-
TYS
1 stop22h 50m
Multiple Airlines
Deal found 3/23$269
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:57 pm
TYS
-
CMH
1 stop6h 24m
American Airlines
Mon 5/47:35 pm
CMH
-
TYS
1 stop4h 20m
American Airlines
Deal found 3/23$286
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:15 pm
TYS
-
CMH
1 stop7h 01m
Multiple Airlines
Sun 4/197:00 pm
CMH
-
TYS
2 stops22h 30m
Multiple Airlines
Deal found 3/24$297
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:15 pm
TYS
-
CMH
1 stop7h 01m
Multiple Airlines
Mon 5/412:00 pm
CMH
-
TYS
2 stops21h 40m
Multiple Airlines
Deal found 3/23$310
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:01 pm
TYS
-
CMH
1 stop5h 56m
United Airlines
Sat 5/1610:38 am
CMH
-
TYS
1 stop6h 16m
United Airlines
Deal found 3/20$314
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:25 pm
TYS
-
CMH
1 stop17h 16m
Multiple Airlines
Thu 4/911:42 am
CMH
-
TYS
1 stop10h 23m
Multiple Airlines
Deal found 3/20$318

Find flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 24, 2026.

Round-trip from

$252
(Kiwi.com)

One-way from

$129
(Kiwi.com)

Popular in

April

Cheapest in

October

Average price

$294
From Knoxville McGhee Tyson to Columbus
Search Deals
One-way flight from Knoxville McGhee Tyson to Columbus
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/23

3:35 pm-10:32 pm

1 stop6h 57m

Columbus

Sun 4/26

7:00 pm-5:30 pm

2 stops22h 30m

$252

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 4/17

1:15 pm-8:16 pm

1 stop7h 01m

Columbus

Sun 4/19

7:00 pm-5:30 pm

2 stops22h 30m

$297

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 5/14

6:01 pm-1:13 am

1 stop7h 12m

Columbus

Sat 5/16

10:38 am-4:54 pm

1 stop6h 16m

$314

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 5/14

6:45 pm-10:05 pm

1 stop3h 20m

Columbus

Sat 5/16

7:35 am-6:30 pm

2 stops10h 55m

$325

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 4/18

6:40 am-5:45 pm

2 stops11h 05m

Columbus

Sun 4/19

6:20 am-11:40 am

1 stop5h 20m

$335

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/23

7:00 am-11:16 am

1 stop4h 16m

Columbus

Mon 4/27

4:10 pm-10:34 pm

1 stop6h 24m

$335
Quickest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 4/18

7:50 am-1:27 pm

1 stop5h 37m

Columbus

Mon 4/20

5:00 pm-9:40 pm

1 stop4h 40m

$344

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/23

8:05 am-6:10 pm

2 stops10h 05m

Columbus

Sun 4/26

1:20 pm-9:05 pm

2 stops7h 45m

$347

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 5/22

6:45 pm-10:05 pm

1 stop3h 20m

Columbus

Mon 5/25

1:15 pm-8:20 pm

2 stops7h 05m

$362
Cheapest one-way

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/23

3:35 pm-5:40 pm

2 stops26h 05m

$141

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus

What is the cheapest month to book a flight from Knoxville to Columbus?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated March 24, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,320 reviews
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,469 reviews
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,492 reviews
Delta
7.9
Good
8,320 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Columbus. You should not have trouble finding flights to Columbus from McGhee Tyson; the airport handles an average of 0 outbound flights to Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Columbus. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Columbus?

    For as low as $314, United Airlines can have you in Columbus from Knoxville in 7h 12m. Airlines will cover a distance of 296 mi.

  • What are the cheapest airlines flying from Knoxville to Columbus round-trip?

    Delta, at $218, was found to be the cheapest airline from Knoxville to Columbus.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Delta is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Columbus?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to Columbus

Discover the top 3 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$367FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$294Average$361FlexibilityNo cancel feeOn-time69%

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