HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Columbus

$175+ Cheap flights from Knoxville (TYS) to Columbus

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Columbus with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:23 pmTYS - CMH
1 stop3h 46mAmerican Airlines
Sun 12/213:37 pmCMH - TYS
1 stop4h 04mAmerican Airlines
Deal found 12/3$329
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:29 pmTYS - CMH
1 stop5h 06mAmerican Airlines
Sat 1/179:04 amCMH - TYS
1 stop6h 52mAmerican Airlines
Deal found 12/3$334
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:59 pmTYS - CMH
1 stop3h 46mDelta
Sat 1/172:16 pmCMH - TYS
1 stop5h 08mDelta
Deal found 12/4$358
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:42 amTYS - CMH
1 stop6h 25mAmerican Airlines
Mon 1/58:23 amCMH - TYS
1 stop5h 58mAmerican Airlines
Deal found 12/3$362
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:09 pmTYS - CMH
1 stop23h 31mMultiple Airlines
Fri 12/1211:14 amCMH - TYS
1 stop6h 06mMultiple Airlines
Deal found 12/3$368
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:38 pmTYS - CMH
1 stop6h 19mMultiple Airlines
Sun 12/219:13 pmCMH - TYS
1 stop24h 40mMultiple Airlines
Deal found 12/2$369
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:53 pmTYS - CMH
2 stops33h 04mMultiple Airlines
Sun 12/219:13 pmCMH - TYS
1 stop24h 40mMultiple Airlines
Deal found 12/4$376
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amTYS - CMH
2 stops13h 38mMultiple Airlines
Sun 12/147:44 pmCMH - TYS
1 stop21h 36mMultiple Airlines
Deal found 12/3$387
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:23 pmTYS - CMH
1 stop4h 21mUnited Airlines
Mon 12/225:40 amCMH - TYS
1 stop4h 35mUnited Airlines
Deal found 12/3$407

Find flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Round-trip from

$175
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$539
From Knoxville McGhee Tyson to Columbus
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.

Fly from

Knoxville

Fly to

Columbus

Route

Depart

Return

Price

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Mon 1/12

2:19 pm-8:31 pm

1 stop6h 12m

Columbus

Wed 1/14

9:45 am-3:56 pm

1 stop6h 11m

$175

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 1/7

11:10 am-7:06 pm

2 stops7h 56m

Columbus

Sat 1/10

12:09 pm-8:52 pm

2 stops8h 43m

$254

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 1/30

7:20 pm-11:44 pm

1 stop4h 24m

Columbus

Mon 2/2

5:45 am-10:32 am

1 stop4h 47m

$271

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sun 1/25

7:20 pm-11:44 pm

1 stop4h 24m

Columbus

Wed 1/28

8:49 am-8:52 pm

2 stops12h 03m

$312

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Mon 1/12

12:55 pm-11:19 pm

1 stop10h 24m

Columbus

Wed 1/14

6:06 am-8:39 am

3 stops26h 33m

$317

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 12/20

5:00 am-11:50 am

2 stops6h 50m

Columbus

Sat 1/17

9:04 am-3:56 pm

1 stop6h 52m

$339

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 12/10

12:53 pm-7:38 pm

2 stops30h 45m

$209

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 12/11

1:22 pm-8:13 pm

3 stops30h 51m

$226

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 12/10

5:40 am-9:00 am

1 stop3h 20m

$274

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 12/9

5:40 am-11:36 am

1 stop5h 56m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus

What is the cheapest month to book a flight from Knoxville to Columbus?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in November is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CMH?

Find hourly flight availability from Knoxville to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s typically best to fly out from Knoxville to Columbus at noon. Doing so could potentially save you 46% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated December 4, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Columbus. You should not have trouble finding flights to Columbus from McGhee Tyson; the airport handles an average of 0 outbound flights to Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Columbus. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Columbus?

    For as low as $175, American Airlines can have you in Columbus from Knoxville in 6h 12m. Airlines will cover a distance of 296 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Columbus round-trip?

    Delta, at $218, was found to be the cheapest airline from Knoxville to Columbus.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Delta is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Columbus?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus (average of $171). Flying from Knoxville to Columbus in November is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Columbus

See prices for flight routes from nearby airports that may be better suited for you.
Memphis to Detroit flights
Nashville to Detroit flights
Nashville to Cleveland flights
Knoxville to Detroit flights
Chattanooga to Pittsburgh flights
Chattanooga to Detroit flights
Nashville to Columbus flights
Memphis to Akron flights
Nashville to Pittsburgh flights
Nashville to Cincinnati flights
Memphis to Columbus flights
Chattanooga to Columbus flights
Chattanooga to Akron flights
Knoxville to Columbus flights
Memphis to Cincinnati flights
Chattanooga to Cleveland flights
Memphis to Cleveland flights
Chattanooga to Cincinnati flights
Nashville to Akron flights
Nashville to Dayton flights
Knoxville to Cleveland flights
Memphis to Dayton flights
Knoxville to Pittsburgh flights
Memphis to Pittsburgh flights
Chattanooga to Dayton flights
Blountville to Cleveland flights
Blountville to Detroit flights
Knoxville to Cincinnati flights
Knoxville to Akron flights
Nashville to Toledo flights
Blountville to Dayton flights
Nashville to Erie flights
Memphis to Huntington flights
Knoxville to Toledo flights
Memphis to Erie flights
Knoxville to Erie flights
Blountville to Pittsburgh flights
Memphis to Toledo flights

Top 3 airlines flying from Knoxville to Columbus

Discover the top 3 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$223Average$293FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$539FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.