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$161+ Cheap flights from Knoxville (TYS) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Jun 23 — Jun 301
Tue 6/23
Tue 6/30
1 adult, Economy
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Cheap flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.

This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:30 am
TYS
-
CMH
1 stop4h 40m
Southwest
Thu 8/612:55 pm
CMH
-
TYS
1 stop5h 40m
Southwest
Deal found 5/20$324
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
TYS
-
CMH
1 stop6h 21m
American Airlines
Mon 7/131:01 pm
CMH
-
TYS
1 stop6h 59m
American Airlines
Deal found 5/21$337
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am
TYS
-
CMH
2 stops5h 30m
Southwest
Sun 10/186:30 am
CMH
-
TYS
1 stop5h 25m
Southwest
Deal found 5/19$339
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:45 am
TYS
-
CMH
1 stop4h 04m
United Airlines
Sun 6/285:20 am
CMH
-
TYS
1 stop4h 23m
United Airlines
Deal found 5/20$354
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:15 am
TYS
-
CMH
1 stop4h 12m
Delta
Thu 6/256:00 am
CMH
-
TYS
1 stop3h 38m
Delta
Deal found 5/21$357
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:40 am
TYS
-
CMH
1 stop5h 45m
Southwest
Thu 6/254:15 pm
CMH
-
TYS
2 stops6h 15m
Southwest
Deal found 5/21$372
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
TYS
-
CMH
1 stop7h 17m
United Airlines
Sun 6/145:20 am
CMH
-
TYS
1 stop4h 23m
United Airlines
Deal found 5/19$377
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
TYS
-
CMH
1 stop6h 06m
United Airlines
Mon 8/176:00 am
CMH
-
TYS
1 stop4h 37m
United Airlines
Deal found 5/19$381

Find flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 24, 2026.

Round-trip from

$324
(Southwest)

One-way from

$161
(Kiwi.com)
From Knoxville McGhee Tyson to Columbus
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One-way flight from Knoxville McGhee Tyson to Columbus
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 10/17

6:00 am-11:54 am

1 stop5h 54m

Columbus

Sun 10/18

5:20 am-9:45 am

1 stop4h 25m

$324

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 7/30

7:30 am-12:10 pm

1 stop4h 40m

Columbus

Thu 8/6

12:55 pm-6:35 pm

1 stop5h 40m

$324

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 7/9

6:00 am-12:21 pm

1 stop6h 21m

Columbus

Mon 7/13

1:01 pm-8:00 pm

1 stop6h 59m

$337

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 10/17

7:00 am-12:30 pm

2 stops5h 30m

Columbus

Sun 10/18

6:30 am-11:55 am

1 stop5h 25m

$339
Quickest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 6/26

5:45 am-9:49 am

1 stop4h 04m

Columbus

Sun 6/28

5:20 am-9:43 am

1 stop4h 23m

$354

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 6/20

7:15 am-1:27 pm

1 stop6h 12m

Columbus

Sat 6/27

6:44 pm-12:02 am

1 stop5h 18m

$357

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 8/13

7:00 am-1:06 pm

1 stop6h 06m

Columbus

Mon 8/17

2:12 pm-8:53 pm

1 stop6h 41m

$381

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 6/18

6:40 am-6:25 pm

2 stops11h 45m

Columbus

Thu 6/25

4:15 pm-10:30 pm

2 stops6h 15m

$383
Cheapest one-way

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Mon 6/1

7:24 pm-5:50 pm

2 stops22h 26m

$161

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 6/19

6:12 am-12:21 pm

1 stop6h 09m

$169

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/19

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated May 24, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,436 reviews

Comfort

7.8

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,436 reviews
Delta
7.9
Good
8,436 reviews

Comfort

7.8

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,749 reviews
Delta
7.9
Good
8,436 reviews

Comfort

7.8

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Columbus. You should not have trouble finding flights to Columbus from McGhee Tyson; the airport handles an average of 0 outbound flights to Columbus per day. You should also have plenty of airline options to choose from since 2 airlines have flights from the Knoxville airport to Columbus. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Columbus?

    For as low as $324, United Airlines can have you in Columbus from Knoxville in 4h 40m. Airlines will cover a distance of 296 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Columbus round-trip?

    Delta, at $218, was found to be the cheapest airline from Knoxville to Columbus. An alternate airline flying to your destination would be United Airlines.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Columbus

Discover the top 2 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$377FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$294Average$361FlexibilityNo cancel feeOn-time69%

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