$110+ Cheap flights from Knoxville (TYS) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Jun 17 — Jun 241
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to ColumbusExplore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:55 pm
TYS
- CMH
1 stop3h 05m
Southwest
Tue 6/234:20 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/18![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:25 pm
TYS
- CMH
1 stop6h 31m
Delta
Tue 7/147:05 am
CMH
- TYS
1 stop4h 00m
Delta
Deal found 5/15![Delta logo]()
$318
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
TYS
- CMH
1 stop4h 04m
United Airlines
Sun 6/146:00 am
CMH
- TYS
1 stop4h 42m
United Airlines
Deal found 5/14![United Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:45 am
TYS
- CMH
1 stop4h 04m
United Airlines
Mon 7/135:30 am
CMH
- TYS
1 stop4h 13m
United Airlines
Deal found 5/15![United Airlines logo]()
$337
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Sat 6/132:19 pm
CMH
- TYS
1 stop6h 37m
United Airlines
Deal found 5/16![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:30 am
TYS
- CMH
2 stops11h 30m
Southwest
Mon 7/135:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/15![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:10 am
TYS
- CMH
2 stops9h 20m
Southwest
Sat 6/1312:30 pm
CMH
- TYS
1 stop8h 50m
Southwest
Deal found 5/16![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Fri 6/192:19 pm
CMH
- TYS
1 stop6h 37m
United Airlines
Deal found 5/15![United Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
- CMH
2 stops14h 19m
Multiple Airlines
Thu 6/258:58 pm
CMH
- TYS
1 stop24h 15m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:30 am
TYS
- CMH
2 stops9h 25m
Southwest
Fri 6/195:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/15![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:30 am
TYS
- CMH
1 stop4h 40m
Southwest
Sun 6/149:00 am
CMH
- TYS
2 stops12h 15m
Southwest
Deal found 5/14![Southwest logo]()
$377
Best flights from Knoxville to ColumbusDiscover carefully curated flight deals from Knoxville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from Knoxville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:10 am
TYS
- CMH
2 stops10h 10m
Southwest
Tue 6/234:20 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/18![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:15 am
TYS
- CMH
1 stop6h 12m
Delta
Sat 6/136:44 pm
CMH
- TYS
1 stop5h 18m
Delta
Deal found 5/16![Delta logo]()
$338
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Sat 6/132:19 pm
CMH
- TYS
1 stop6h 37m
United Airlines
Deal found 5/16![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
- CMH
2 stops9h 20m
Southwest
Wed 6/245:00 am
CMH
- TYS
1 stop12h 00m
Southwest
Deal found 5/14![Southwest logo]()
$310
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Fri 6/192:19 pm
CMH
- TYS
1 stop6h 37m
United Airlines
Deal found 5/15![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:10 am
TYS
- CMH
2 stops9h 20m
Southwest
Sat 6/1312:30 pm
CMH
- TYS
1 stop8h 50m
Southwest
Deal found 5/16![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Sun 6/216:00 am
CMH
- TYS
1 stop4h 42m
United Airlines
Deal found 5/16![United Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:30 am
TYS
- CMH
2 stops11h 30m
Southwest
Mon 7/134:15 pm
CMH
- TYS
2 stops6h 15m
Southwest
Deal found 5/15![Southwest logo]()
$357
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:10 am
TYS
- CMH
1 stop4h 05m
Southwest
Sun 11/86:30 am
CMH
- TYS
1 stop5h 40m
Southwest
Deal found 5/13![Southwest logo]()
$357
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:30 am
TYS
- CMH
2 stops9h 25m
Southwest
Fri 6/194:15 pm
CMH
- TYS
2 stops6h 15m
Southwest
Deal found 5/15![Southwest logo]()
$377
Last-minute flights from Knoxville to ColumbusDiscover last-minute flight deals from Knoxville to Columbus. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Columbus. Data last updated May 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:15 am
TYS
- CMH
1 stop6h 12m
Delta
Sat 6/136:44 pm
CMH
- TYS
1 stop5h 18m
Delta
Deal found 5/16![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:10 am
TYS
- CMH
2 stops9h 20m
Southwest
Sat 6/1312:30 pm
CMH
- TYS
1 stop8h 50m
Southwest
Deal found 5/16![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
TYS
- CMH
1 stop4h 04m
United Airlines
Sun 6/146:00 am
CMH
- TYS
1 stop4h 42m
United Airlines
Deal found 5/14![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:30 am
TYS
- CMH
1 stop4h 40m
Southwest
Sun 6/149:00 am
CMH
- TYS
2 stops12h 15m
Southwest
Deal found 5/14![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Fri 6/192:19 pm
CMH
- TYS
1 stop6h 37m
United Airlines
Deal found 5/15![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:30 am
TYS
- CMH
2 stops9h 25m
Southwest
Fri 6/195:35 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/15![Southwest logo]()
$372
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:03 pm
TYS
- CMH
1 stop4h 39m
American Airlines
Fri 6/191:01 pm
CMH
- TYS
1 stop7h 09m
American Airlines
Deal found 5/15![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 am
TYS
- CMH
1 stop7h 17m
United Airlines
Sun 6/216:00 am
CMH
- TYS
1 stop4h 42m
United Airlines
Deal found 5/16![United Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:55 pm
TYS
- CMH
1 stop3h 05m
Southwest
Tue 6/234:20 pm
CMH
- TYS
1 stop4h 55m
Southwest
Deal found 5/18![Southwest logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
- CMH
2 stops14h 19m
Multiple Airlines
Thu 6/258:58 pm
CMH
- TYS
1 stop24h 15m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
- CMH
2 stops9h 20m
Southwest
Wed 6/2411:55 am
CMH
- TYS
2 stops8h 25m
Southwest
Deal found 5/14![Southwest logo]()
$398
One-way flights from Knoxville to ColumbusSearch for one-way flight options from Knoxville to Columbus. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from Knoxville to Columbus. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 pm
TYS
- CMH
2 stops28h 25m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$110
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:00 am
TYS
- CMH
1 stop3h 47m
American Airlines
Deal found 5/17![American Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:03 pm
TYS
- CMH
2 stops19h 47m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:46 pm
TYS
- CMH
2 stops23h 24m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:25 am
TYS
- CMH
2 stops31h 45m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$168
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:56 am
TYS
- CMH
1 stop3h 56m
Delta
Deal found 5/16![Delta logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:03 pm
TYS
- CMH
2 stops35h 04m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 pm
TYS
- CMH
2 stops24h 48m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:27 pm
TYS
- CMH
2 stops22h 21m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:10 am
TYS
- CMH
2 stops7h 50m
Southwest
Deal found 5/17![Southwest logo]()
$204
Find flight deals from Knoxville to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 18, 2026.
Round-trip from | $299 (United Airlines) |
|---|---|
One-way from | $110 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Wed 6/17
7:10 am-5:20 pm
2 stops10h 10m
Columbus
Tue 6/23
4:20 pm-9:15 pm
1 stop4h 55m
$310
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Tue 6/23
8:10 am-5:30 pm
2 stops9h 20m
Columbus
Wed 6/24
5:00 am-5:00 pm
1 stop12h 00m
$310
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Wed 6/10
7:15 am-1:27 pm
1 stop6h 12m
Columbus
Sat 6/13
6:44 pm-12:02 am
1 stop5h 18m
$338
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Wed 6/10
6:00 am-1:17 pm
1 stop7h 17m
Columbus
Sat 6/13
2:19 pm-8:56 pm
1 stop6h 37m
$338
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Wed 6/10
8:10 am-5:30 pm
2 stops9h 20m
Columbus
Sat 6/13
12:30 pm-9:20 pm
1 stop8h 50m
$349
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 6/12
6:00 am-1:17 pm
1 stop7h 17m
Columbus
Fri 6/19
2:19 pm-8:56 pm
1 stop6h 37m
$357
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Thu 7/9
7:30 am-7:00 pm
2 stops11h 30m
Columbus
Mon 7/13
4:15 pm-10:30 pm
2 stops6h 15m
$357
Quickest round-trip
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 11/6
8:10 am-12:15 pm
1 stop4h 05m
Columbus
Sun 11/8
6:30 am-12:10 pm
1 stop5h 40m
$357
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Fri 6/12
7:30 am-4:55 pm
2 stops9h 25m
Columbus
Fri 6/19
4:15 pm-10:30 pm
2 stops6h 15m
$377
KnoxvilleColumbus
TYS - CMH
TYSCMH
Knoxville McGhee Tyson
Sun 6/14
6:00 am-1:17 pm
1 stop7h 17m
Columbus
Sun 6/21
6:00 am-10:42 am
1 stop4h 42m
$390
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
TYS-C01
TYS-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Columbus
TYS-C01
TYS-CMH
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated May 18, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
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Top 2 airlines flying from Knoxville to Columbus
Discover the top 2 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$377 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$294 | Average$361 | FlexibilityNo cancel fee | On-time69% |