Columbus

$125+ Cheap flights from Knoxville (TYS) to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Jul 18 — Jul 251
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Cheap flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:15 am
TYS
-
CMH
1 stop6h 12m
Delta
Wed 7/158:11 am
CMH
-
TYS
1 stop5h 05m
Delta
Deal found 6/14$265
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:10 am
TYS
-
CMH
2 stops7h 50m
Southwest
Wed 7/154:20 pm
CMH
-
TYS
1 stop5h 00m
Southwest
Deal found 6/14$270
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:40 am
TYS
-
CMH
1 stop7h 04m
American Airlines
Thu 8/136:00 am
CMH
-
TYS
1 stop3h 43m
American Airlines
Deal found 6/16$279
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:10 am
TYS
-
CMH
2 stops10h 20m
Southwest
Tue 7/2112:55 pm
CMH
-
TYS
2 stops8h 25m
Southwest
Deal found 6/16$281
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
TYS
-
CMH
2 stops7h 55m
Southwest
Thu 8/137:30 am
CMH
-
TYS
1 stop5h 55m
Southwest
Deal found 6/16$284
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:50 pm
TYS
-
CMH
1 stop6h 15m
Multiple Airlines
Sun 8/165:44 pm
CMH
-
TYS
2 stops14h 52m
Multiple Airlines
Deal found 6/15$289
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:52 pm
TYS
-
CMH
1 stop4h 41m
American Airlines
Thu 8/134:23 pm
CMH
-
TYS
1 stop6h 35m
American Airlines
Deal found 6/16$293
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
-
CMH
1 stop15h 39m
Multiple Airlines
Thu 8/135:44 pm
CMH
-
TYS
2 stops14h 52m
Multiple Airlines
Deal found 6/16$295
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:00 am
TYS
-
CMH
1 stop3h 47m
American Airlines
Sat 7/42:00 pm
CMH
-
TYS
1 stop3h 49m
American Airlines
Deal found 6/15$299
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:05 pm
TYS
-
CMH
1 stop3h 51m
American Airlines
Mon 7/205:26 pm
CMH
-
TYS
1 stop6h 25m
American Airlines
Deal found 6/16$301
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:40 pm
TYS
-
CMH
1 stop6h 25m
Multiple Airlines
Wed 7/159:54 am
CMH
-
TYS
2 stops26h 15m
Multiple Airlines
Deal found 6/13$302
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:45 pm
TYS
-
CMH
2 stops10h 05m
Southwest
Sat 7/48:55 am
CMH
-
TYS
1 stop2h 55m
Southwest
Deal found 6/15$304

Find flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2026.

Round-trip from

$265
(American Airlines)

One-way from

$125
(Kiwi.com)
From Knoxville McGhee Tyson to Columbus
One-way flight from Knoxville McGhee Tyson to Columbus

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 7/14

7:10 am-5:30 pm

2 stops10h 20m

Columbus

Tue 7/21

12:55 pm-9:20 pm

2 stops8h 25m

$281

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 6/30

12:45 pm-10:50 pm

2 stops10h 05m

Columbus

Sat 7/4

8:55 am-11:50 am

1 stop2h 55m

$304

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 7/15

8:10 am-5:30 pm

2 stops9h 20m

Columbus

Mon 7/20

11:55 am-10:35 pm

2 stops10h 40m

$311

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 7/11

7:00 am-12:15 pm

1 stop5h 15m

Columbus

Tue 7/14

5:40 am-12:05 pm

2 stops6h 25m

$326

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 8/18

6:02 pm-11:59 pm

1 stop5h 57m

Columbus

Wed 8/19

11:05 am-4:58 pm

1 stop5h 53m

$335

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 7/4

12:30 pm-7:05 pm

1 stop6h 35m

Columbus

Sat 7/11

6:50 am-11:55 am

1 stop5h 05m

$338
Quickest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 7/9

3:59 pm-9:02 pm

1 stop5h 03m

Columbus

Sun 7/12

8:08 pm-11:52 pm

1 stop3h 44m

$357
Cheapest one-way

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Mon 8/3

12:53 pm-4:59 pm

2 stops28h 06m

$125
Quickest one-way

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 8/1

8:05 pm-11:56 pm

1 stop3h 51m

$169

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 8/1

8:40 pm-12:43 pm

3 stops16h 03m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Sorted by cheapest first

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated June 18, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Columbus. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.3

Boarding

7.7

Overall

7.4

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Comfort

7.3

Boarding

7.7

Overall

7.4

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Comfort

7.3

Boarding

7.7

Overall

7.4

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Columbus. You should not have trouble finding flights to Columbus from McGhee Tyson; the airport handles an average of 0 outbound flights to Columbus per day. You should also have plenty of airline options to choose from since 2 airlines have flights from the Knoxville airport to Columbus. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Columbus?

    For as low as $335, Southwest can have you in Columbus from Knoxville in 5h 57m. Airlines will cover a distance of 296 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Columbus round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Knoxville to Columbus. An alternate airline flying to your destination would be United Airlines.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Columbus

Discover the top 2 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$326FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$294Average$361FlexibilityNo cancel feeOn-time69%

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