How long is the flight from South Carolina to Columbia, Missouri?

Departing from South Carolina to Columbia, Missouri will take you 5h 37m. South Carolina and Columbia, Missouri are separated by a distance of 794 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Columbia, Missouri ranges from 1.9 - 5.0 inches per month. May is typically the wettest month, when rainfall can reach 5.0 in. January is typically the driest time to visit Columbia, Missouri when rainfall is around 1.9 in.

If weather is an important factor for your trip to Columbia, Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

What are the most popular routes from South Carolina to Columbia, Missouri?

While some choose either Charlotte Douglas - Columbia Regional or Columbia Metropolitan - Columbia Regional, Charleston - Columbia Regional is the most popular route from South Carolina to Columbia, Missouri.

What is the cheapest time of day to fly from SC to COU?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Columbia, Missouri as you normally would.

What airport do you fly into for flights to Columbia from South Carolina?

Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly into when you book flights from South Carolina to Columbia.

Can I find deals for flights from South Carolina to Columbia that include hotel bookings?

Yes. In addition to deals on South Carolina to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Columbia?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Columbia.

Can I find deals for business class flights from South Carolina to Columbia?

Yes. Cheapflights offers flight deals from South Carolina to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$255+ Flights from South Carolina to Columbia, MO

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Cheap flight deals from South Carolina to Columbia

Cheapest flights from South Carolina to Columbia
Explore the most affordable flight options available from South Carolina to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

Tue 12/305:09 pmCLT - COU

1 stop5h 10mUnited Airlines

Sat 1/33:10 pmCOU - CLT

1 stop5h 10mUnited Airlines

Deal found 12/15

$418

Tue 12/302:30 pmCAE - COU

1 stop7h 49mUnited Airlines

Sat 1/36:34 pmCOU - CAE

1 stop4h 52mUnited Airlines

Deal found 12/15

$443

Wed 12/246:00 amCAE - COU

1 stop6h 39mAmerican Airlines

Sat 12/273:19 pmCOU - CAE

2 stops7h 56mAmerican Airlines

Deal found 12/16

$475

Wed 12/318:15 amCLT - COU

1 stop7h 34mAmerican Airlines

Sun 1/47:42 pmCOU - CLT

1 stop13h 37mAmerican Airlines

Deal found 12/16

$486

Mon 12/294:59 pmCHS - COU

1 stop5h 20mUnited Airlines

Wed 12/316:34 pmCOU - CHS

2 stops14h 50mUnited Airlines

Deal found 12/16

$498

Wed 12/312:54 pmCLT - COU

2 stops7h 25mUnited Airlines

Sun 1/43:10 pmCOU - CLT

1 stop5h 10mUnited Airlines

Deal found 12/16

$501

Tue 12/306:45 amCHS - COU

2 stops8h 50mUnited Airlines

Wed 12/313:10 pmCOU - CHS

2 stops18h 14mUnited Airlines

Deal found 12/15

$503

Tue 12/304:25 pmAGS - COU

1 stop7h 07mAmerican Airlines

Sat 1/33:19 pmCOU - AGS

2 stops7h 47mAmerican Airlines

Deal found 12/15

$560

Best flights from South Carolina to Columbia
Discover carefully curated flight deals from South Carolina to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 17, 2025.

Thu 1/226:05 amCHS - COU

1 stop5h 37mUnited Airlines

Mon 1/268:09 amCOU - CHS

1 stop4h 53mUnited Airlines

Deal found 12/15

$328

Thu 1/157:50 amCLT - COU

1 stop7h 58mAmerican Airlines

Sun 1/1811:56 amCOU - CLT

1 stop9h 58mAmerican Airlines

Deal found 12/16

$390

Thu 1/86:05 amCHS - COU

1 stop5h 37mUnited Airlines

Mon 1/128:09 amCOU - CHS

1 stop4h 53mUnited Airlines

Deal found 12/14

$328

Sat 1/1010:10 amCAE - COU

1 stop8h 09mUnited Airlines

Tue 1/138:45 amCOU - CAE

2 stops13h 59mUnited Airlines

Deal found 12/14

$369

Sat 2/1410:42 amCLT - COU

1 stop4h 46mUnited Airlines

Tue 2/1711:15 amCOU - CLT

1 stop5h 09mUnited Airlines

Deal found 12/14

$400

Tue 12/305:09 pmCLT - COU

1 stop5h 10mUnited Airlines

Sat 1/33:10 pmCOU - CLT

1 stop5h 10mUnited Airlines

Deal found 12/15

$418

Tue 12/304:25 pmAGS - COU

1 stop7h 07mAmerican Airlines

Sat 1/33:19 pmCOU - AGS

2 stops7h 47mAmerican Airlines

Deal found 12/15

$560

Tue 12/302:30 pmCAE - COU

1 stop7h 49mUnited Airlines

Sat 1/36:34 pmCOU - CAE

1 stop4h 52mUnited Airlines

Deal found 12/15

$443

Tue 12/304:59 pmCHS - COU

1 stop5h 20mUnited Airlines

Wed 12/316:34 pmCOU - CHS

2 stops14h 50mUnited Airlines

Deal found 12/15

$498

Mon 12/294:59 pmCHS - COU

1 stop5h 20mUnited Airlines

Wed 12/316:34 pmCOU - CHS

2 stops14h 50mUnited Airlines

Deal found 12/16

$498

Last-minute flights from South Carolina to Columbia
Discover last-minute flight deals from South Carolina to Columbia. Data last updated December 17, 2025 and is based on user searches.

Wed 12/246:00 amCAE - COU

1 stop6h 39mAmerican Airlines

Sat 12/273:19 pmCOU - CAE

2 stops7h 56mAmerican Airlines

Deal found 12/16

$475

Mon 12/294:59 pmCHS - COU

1 stop5h 20mUnited Airlines

Wed 12/316:34 pmCOU - CHS

2 stops14h 50mUnited Airlines

Deal found 12/16

$498

Tue 12/305:09 pmCLT - COU

1 stop5h 10mUnited Airlines

Sat 1/33:10 pmCOU - CLT

1 stop5h 10mUnited Airlines

Deal found 12/15

$418

Tue 12/302:30 pmCAE - COU

1 stop7h 49mUnited Airlines

Sat 1/36:34 pmCOU - CAE

1 stop4h 52mUnited Airlines

Deal found 12/15

$443

Tue 12/306:45 amCHS - COU

2 stops8h 50mUnited Airlines

Wed 12/313:10 pmCOU - CHS

2 stops18h 14mUnited Airlines

Deal found 12/15

$503

Wed 12/318:15 amCLT - COU

1 stop7h 34mAmerican Airlines

Sun 1/47:42 pmCOU - CLT

1 stop13h 37mAmerican Airlines

Deal found 12/16

$486

Wed 12/312:54 pmCLT - COU

2 stops7h 25mUnited Airlines

Sun 1/43:10 pmCOU - CLT

1 stop5h 10mUnited Airlines

Deal found 12/16

$501

Sat 1/1010:10 amCAE - COU

1 stop5h 25mUnited Airlines

Tue 1/133:10 pmCOU - CAE

2 stops7h 34mUnited Airlines

Deal found 12/16

$369

Thu 1/157:50 amCLT - COU

1 stop7h 58mAmerican Airlines

Sun 1/1811:56 amCOU - CLT

1 stop9h 58mAmerican Airlines

Deal found 12/16

$390

Thu 1/1511:15 amCLT - COU

2 stops11h 22mUnited Airlines

Sun 1/1811:17 amCOU - CLT

1 stop5h 07mUnited Airlines

Deal found 12/16

$476

Thu 1/224:41 pmCHS - COU

1 stop5h 56mUnited Airlines

Mon 1/2611:17 amCOU - CHS

1 stop7h 45mUnited Airlines

Deal found 12/16

$328

Thu 1/296:10 amCLT - COU

1 stop16h 27mUnited Airlines

Thu 2/58:09 amCOU - CLT

1 stop8h 15mUnited Airlines

Deal found 12/15

$475

One-way flights from South Carolina to Columbia
Search for one-way flight options from South Carolina to Columbia. Find affordable one-way fares based on user searches. Data last updated December 17, 2025.

Thu 1/297:32 amCHS - COU

1 stop5h 47mAmerican Airlines

Deal found 12/16

$255

Sat 1/106:10 amCLT - COU

1 stop9h 25mUnited Airlines

Deal found 12/17

$278

Fri 1/304:19 pmCLT - COU

1 stop29h 14mUnited Airlines

Deal found 12/16

$283

Mon 1/510:41 pmCLT - COU

1 stop13h 42mAmerican Airlines

Deal found 12/16

$427

Fri 12/261:25 pmCLT - COU

1 stop5h 10mAmerican Airlines

Deal found 12/15

$530

Fri 12/266:00 amCLT - COU

2 stops9h 35mUnited Airlines

Deal found 12/15

$536

Find flight deals from South Carolina to Columbia

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Most trusted provider	eDreams 3 stars
Round-trip from	$328 (United Airlines)
One-way from	$255 (American Airlines)

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From South Carolina to Columbia Regional

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One-way flight from South Carolina to Columbia Regional

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Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Thu 1/22

6:05 am-10:42 am

1 stop5h 37m

Columbia Regional

Mon 1/26

8:09 am-2:02 pm

1 stop4h 53m

$328

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Thu 1/8

6:05 am-10:42 am

1 stop5h 37m

Columbia Regional

Mon 1/12

8:09 am-2:02 pm

1 stop4h 53m

$328

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Sat 1/10

10:10 am-5:19 pm

1 stop8h 09m

Columbia Regional

Tue 1/13

8:45 am-11:44 pm

2 stops13h 59m

$369

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Thu 1/15

7:50 am-2:48 pm

1 stop7h 58m

Columbia Regional

Sun 1/18

11:56 am-10:54 pm

1 stop9h 58m

$390

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Sat 2/14

10:42 am-2:28 pm

1 stop4h 46m

Columbia Regional

Tue 2/17

11:15 am-5:24 pm

1 stop5h 09m

$400

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Tue 12/30

5:09 pm-9:19 pm

1 stop5h 10m

Columbia Regional

Sat 1/3

3:10 pm-9:20 pm

1 stop5h 10m

$418

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Tue 12/30

2:30 pm-9:19 pm

1 stop7h 49m

Columbia Regional

Sat 1/3

6:34 pm-12:26 am

1 stop4h 52m

$443

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Tue 12/30

4:59 pm-9:19 pm

1 stop5h 20m

Columbia Regional

Wed 12/31

6:34 pm-10:24 am

2 stops14h 50m

$498

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Mon 12/29

4:59 pm-9:19 pm

1 stop5h 20m

Columbia Regional

Wed 12/31

6:34 pm-10:24 am

2 stops14h 50m

$498

AugustaColumbia

AGS - COU

AGSCOU

Augusta Bush Field

Tue 12/30

4:25 pm-10:32 pm

1 stop7h 07m

Columbia Regional

Sat 1/3

3:19 pm-12:06 am

2 stops7h 47m

$560

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 17 results

Best time to book a flight from South Carolina to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Columbia

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Columbia from South Carolina?
Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly into when you book flights from South Carolina to Columbia.
How long is the flight from South Carolina to Columbia, Missouri?
Departing from South Carolina to Columbia, Missouri will take you 5h 37m. South Carolina and Columbia, Missouri are separated by a distance of 794 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from South Carolina to Columbia, Missouri?
While some choose either Charlotte Douglas - Columbia Regional or Columbia Metropolitan - Columbia Regional, Charleston - Columbia Regional is the most popular route from South Carolina to Columbia, Missouri.
Can I find deals for flights from South Carolina to Columbia that include hotel bookings?
Yes. In addition to deals on South Carolina to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Columbia?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Columbia.
Can I find deals for business class flights from South Carolina to Columbia?
Yes. Cheapflights offers flight deals from South Carolina to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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$255+ Cheap flights from South Carolina to Columbia, MO (COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Columbia with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Columbia

Cheapest flights from South Carolina to ColumbiaExplore the most affordable flight options available from South Carolina to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

Explore the most affordable flight options available from South Carolina to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

Find flight deals from South Carolina to Columbia

Keep the following information in mind while searching for South Carolina to Columbia flight deals. Data was last updated December 17, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Columbia that are best for you.

Best time to book a flight from South Carolina to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Columbia

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Columbia from South Carolina?

How long is the flight from South Carolina to Columbia, Missouri?

What are the most popular routes from South Carolina to Columbia, Missouri?

Can I find deals for flights from South Carolina to Columbia that include hotel bookings?

How can I find direct flights from South Carolina to Columbia?

Can I find deals for business class flights from South Carolina to Columbia?

Traveling to a place near Columbia?

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Cheapest flights from South Carolina to Columbia
Explore the most affordable flight options available from South Carolina to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.