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Columbia

$243+ Cheap flights from South Carolina to Columbia, MO (COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — COU
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Columbia

Cheapest flights from South Carolina to Columbia
Explore the most affordable flight options available from South Carolina to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/126:00 am
CLT
-
COU
1 stop5h 33m
United Airlines
Mon 2/1611:15 am
COU
-
CLT
2 stops8h 54m
United Airlines
Deal found 1/28$274
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:15 am
CLT
-
COU
1 stop5h 33m
United Airlines
Mon 6/293:16 pm
COU
-
CLT
1 stop5h 07m
United Airlines
Deal found 1/28$293
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:15 am
CHS
-
COU
1 stop5h 20m
United Airlines
Sun 2/158:00 am
COU
-
CHS
1 stop4h 52m
United Airlines
Deal found 1/27$298
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:10 am
CLT
-
COU
1 stop5h 32m
United Airlines
Tue 2/103:10 pm
COU
-
CLT
1 stop5h 27m
United Airlines
Deal found 1/27$298
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
CHS
-
COU
1 stop5h 55m
United Airlines
Sun 5/1011:32 am
COU
-
CHS
1 stop5h 30m
United Airlines
Deal found 1/28$328
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:15 am
CLT
-
COU
1 stop5h 33m
United Airlines
Fri 6/1911:23 am
COU
-
CLT
1 stop5h 21m
United Airlines
Deal found 1/27$328
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/210:44 am
CLT
-
COU
1 stop4h 51m
United Airlines
Mon 2/93:10 pm
COU
-
CLT
1 stop5h 27m
United Airlines
Deal found 1/27$343
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:32 pm
CAE
-
COU
1 stop7h 01m
United Airlines
Wed 3/49:00 am
COU
-
CAE
2 stops13h 44m
United Airlines
Deal found 1/27$369
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
CHS
-
COU
1 stop5h 48m
United Airlines
Sat 6/203:16 pm
COU
-
CHS
1 stop5h 34m
United Airlines
Deal found 1/28$403
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:22 pm
CLT
-
COU
Nonstop2h 15m
American Airlines
Fri 6/197:00 am
COU
-
CLT
Nonstop2h 15m
American Airlines
Deal found 1/27$403
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3110:30 am
CHS
-
COU
1 stop5h 05m
United Airlines
Tue 2/38:09 am
COU
-
CHS
1 stop4h 53m
United Airlines
Deal found 1/26$413
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:05 pm
CHS
-
COU
1 stop5h 28m
United Airlines
Tue 2/178:00 am
COU
-
CHS
1 stop4h 52m
United Airlines
Deal found 1/28$418

Find flight deals from South Carolina to Columbia

Keep the following information in mind while searching for South Carolina to Columbia flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$274
(United Airlines)

One-way from

$243
(United Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Columbia Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Columbia Regional flights.
Search Deals
From South Carolina to Columbia Regional
Search Deals
One-way flight from South Carolina to Columbia Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from South Carolina to Columbia that are best for you.

Fly from

South Carolina

Fly to

Columbia

Route

Depart

Return

Price

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Thu 2/12

6:00 am-10:33 am

1 stop5h 33m

Columbia Regional

Mon 2/16

11:15 am-9:09 pm

2 stops8h 54m

$274

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Mon 6/22

6:15 am-10:48 am

1 stop5h 33m

Columbia Regional

Mon 6/29

3:16 pm-9:23 pm

1 stop5h 07m

$293

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Wed 2/11

10:15 am-2:35 pm

1 stop5h 20m

Columbia Regional

Sun 2/15

8:00 am-1:52 pm

1 stop4h 52m

$298

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Sun 2/15

6:15 am-10:33 am

1 stop5h 18m

Columbia Regional

Sun 2/22

11:15 am-5:24 pm

1 stop5h 09m

$298

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Thu 6/11

6:15 am-10:48 am

1 stop5h 33m

Columbia Regional

Fri 6/19

11:23 am-5:44 pm

1 stop5h 21m

$328

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Wed 2/25

3:32 pm-9:33 pm

1 stop7h 01m

Columbia Regional

Wed 3/4

9:00 am-11:44 pm

2 stops13h 44m

$369

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Thu 6/11

9:22 pm-10:37 pm

Nonstop2h 15m

Columbia Regional

Fri 6/19

7:00 am-10:15 am

Nonstop2h 15m

$403

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Thu 6/11

6:00 am-10:48 am

1 stop5h 48m

Columbia Regional

Sat 6/20

3:16 pm-9:50 pm

1 stop5h 34m

$403

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Fri 2/13

5:05 pm-9:33 pm

1 stop5h 28m

Columbia Regional

Tue 2/17

8:00 am-1:52 pm

1 stop4h 52m

$418

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Mon 6/22

9:22 pm-10:37 pm

Nonstop2h 15m

Columbia Regional

Mon 6/29

7:00 am-10:15 am

Nonstop2h 15m

$423

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 29 results
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Best time to book a flight from South Carolina to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Columbia
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Columbia from South Carolina?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly into when you book flights from South Carolina to Columbia.

  • How long is the flight from South Carolina to Columbia, Missouri?

    Departing from South Carolina to Columbia, Missouri will take you 5h 33m. South Carolina and Columbia, Missouri are separated by a distance of 669 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Columbia, Missouri?

    While some choose either Columbia Metropolitan - Columbia Regional or Charleston - Columbia Regional, Charlotte Douglas - Columbia Regional is the most popular route from South Carolina to Columbia, Missouri.

  • Can I find deals for flights from South Carolina to Columbia that include hotel bookings?

    Yes. In addition to deals on South Carolina to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Columbia.

  • Can I find deals for business class flights from South Carolina to Columbia?

    Yes. Cheapflights offers flight deals from South Carolina to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City

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