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$172+ Cheap flights from Durham, NC to Columbia, MO (COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — COU
May 13 — May 201
Wed 5/13
Wed 5/20
1 adult, Economy
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Cheap flight deals from Durham to Columbia

Cheapest flights from Durham to Columbia
Explore the most affordable flight options available from Durham to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 13, 2026.

This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:00 am
RDU
-
COU
1 stop7h 35m
American Airlines
Mon 5/114:28 pm
COU
-
RDU
1 stop6h 30m
American Airlines
Deal found 4/12$318
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:54 pm
RDU
-
COU
1 stop6h 36m
American Airlines
Sat 5/24:28 pm
COU
-
RDU
1 stop6h 31m
American Airlines
Deal found 4/10$323
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:26 pm
RDU
-
COU
1 stop5h 37m
United Airlines
Mon 5/115:00 am
COU
-
RDU
2 stops8h 06m
United Airlines
Deal found 4/12$324
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:54 pm
RDU
-
COU
1 stop6h 35m
American Airlines
Thu 5/146:00 am
COU
-
RDU
1 stop5h 57m
American Airlines
Deal found 4/8$338
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:00 am
RDU
-
COU
1 stop7h 35m
American Airlines
Tue 4/286:00 am
COU
-
RDU
1 stop5h 58m
American Airlines
Deal found 4/9$348
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:25 pm
RDU
-
COU
1 stop5h 36m
United Airlines
Tue 4/285:00 am
COU
-
RDU
2 stops10h 20m
United Airlines
Deal found 4/9$354

Find flight deals from Durham to Columbia

Keep the following information in mind while searching for Durham to Columbia flight deals. Data was last updated April 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$318
(American Airlines)

One-way from

$172
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$413
Provider with most accurate pricing for Raleigh-Durham-Columbia Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Columbia Regional flights.
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From Durham to Columbia Regional
Search Deals
One-way flight from Durham to Columbia Regional
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 13, 2026.
Use the filters below to find and compare flights from Durham to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Sat 5/23

6:15 am-10:48 am

1 stop5h 33m

Columbia Regional

Sat 5/30

8:00 am-2:01 pm

1 stop5h 01m

$318

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Thu 4/30

3:54 pm-9:30 pm

1 stop6h 36m

Columbia Regional

Sat 5/2

4:28 pm-11:59 pm

1 stop6h 31m

$323

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Fri 5/8

5:26 pm-10:03 pm

1 stop5h 37m

Columbia Regional

Mon 5/11

5:00 am-2:06 pm

2 stops8h 06m

$324

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Fri 4/24

5:25 pm-10:01 pm

1 stop5h 36m

Columbia Regional

Tue 4/28

5:00 am-4:20 pm

2 stops10h 20m

$354

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Fri 6/12

4:28 pm-10:46 pm

1 stop7h 18m

Columbia Regional

Mon 6/22

5:19 pm-11:44 pm

1 stop5h 25m

$458

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Fri 6/12

6:15 am-10:48 am

1 stop5h 33m

Columbia Regional

Mon 6/22

5:00 am-12:33 pm

1 stop6h 33m

$463

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Thu 5/7

6:00 am-2:32 pm

2 stops9h 32m

Columbia Regional

Thu 5/14

11:30 am-11:49 pm

2 stops11h 19m

$483
Cheapest one-way

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Mon 6/1

9:03 pm-10:54 am

3 stops38h 51m

$172
Quickest one-way

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Mon 6/1

6:25 pm-10:46 pm

1 stop5h 21m

$273

RaleighColumbia

RDU - COU

RDUCOU

Raleigh-Durham

Sat 5/23

11:13 am-6:13 pm

2 stops8h 00m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/11

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Durham to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Columbia

How much does it cost to fly round-trip from Durham to Columbia, Missouri?

Reviews of airlines servicing Columbia

Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated April 13, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Durham to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,579 reviews

Crew

8.1

Overall

7.4

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,579 reviews
United Airlines
7.4
Good
9,579 reviews

Crew

8.1

Overall

7.4

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,568 reviews
United Airlines
7.4
Good
9,579 reviews

Crew

8.1

Overall

7.4

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Durham to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Columbia from Durham?

    Located just 11.1 mi from the city center, Columbia Regional is the airport most travelers will use when flying to Columbia from Durham. Booking flights from Durham to Columbia Regional (COU) should be relatively easy as there are 0 daily inbound flights from Durham from 2 different airlines.

  • How long is the flight from Durham to Columbia, Missouri?

    Departing from Durham to Columbia, Missouri will take you 5h 33m. There are 764 mi between Durham and Columbia, Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Durham to Columbia that include hotel bookings?

    Yes. In addition to deals on Durham to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Columbia.

  • Can I find deals for business class flights from Durham to Columbia?

    Yes. Cheapflights offers flight deals from Durham to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City

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Top 2 airlines flying from Durham to Columbia

Discover the top 2 airlines that operate flights from Durham to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$258Average$354FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$318Average$474FlexibilityNo cancel feeOn-time71%

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