$232+ Cheap flights from Durham, NC to Columbia, MO (COU)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — COU
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Durham to ColumbiaExplore the most affordable flight options available from Durham to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Durham to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:05 am -
1 stop11h 27m
Fri 9/255:31 pm -
1 stop23h 19m
Deal found 9/3![Multiple Airlines logo]()
$232
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:01 am -
1 stop5h 03m
Fri 11/276:28 pm -
1 stop4h 39m
Deal found 9/3![American Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:42 pm -
1 stop6h 04m
Sat 9/2610:38 am -
1 stop7h 51m
Deal found 9/7![American Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop4h 58m
Mon 10/266:25 pm -
1 stop4h 34m
Deal found 9/4![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:00 pm -
1 stop6h 55m
Sat 9/2611:19 am -
2 stops9h 40m
Deal found 9/7![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:05 am -
1 stop5h 34m
Tue 9/293:19 pm -
1 stop5h 27m
Deal found 9/3![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:42 pm -
1 stop6h 46m
Fri 9/118:16 am -
1 stop5h 30m
Deal found 9/3![American Airlines logo]()
$413
Best flights from Durham to ColumbiaDiscover carefully curated flight deals from Durham to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Durham to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:05 am -
1 stop5h 34m
Tue 9/293:19 pm -
1 stop5h 27m
Deal found 9/3![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:17 am -
2 stops7h 41m
Fri 11/276:28 pm -
1 stop4h 39m
Deal found 9/7![American Airlines logo]()
$493
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:05 am -
1 stop5h 34m
Sat 10/103:19 pm -
2 stops7h 40m
Deal found 9/5![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:05 am -
1 stop7h 33m
Fri 10/911:15 am -
1 stop6h 33m
Deal found 9/3![United Airlines logo]()
$473
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:00 pm -
1 stop6h 55m
Fri 9/256:15 am -
1 stop27h 33m
Deal found 9/3![United Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:55 pm -
3 stops33h 03m
Mon 11/98:00 am -
2 stops12h 19m
Deal found 9/3![United Airlines logo]()
$600
Last-minute flights from Durham to ColumbiaDiscover last-minute flight deals from Durham to Columbia. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to Columbia. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:42 pm -
1 stop6h 46m
Fri 9/118:16 am -
1 stop5h 30m
Deal found 9/3![American Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:05 am -
1 stop11h 27m
Fri 9/255:31 pm -
1 stop23h 19m
Deal found 9/3![Multiple Airlines logo]()
$232
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:42 pm -
1 stop6h 04m
Sat 9/2610:38 am -
1 stop7h 51m
Deal found 9/7![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:00 pm -
1 stop6h 55m
Sat 9/2611:19 am -
2 stops9h 40m
Deal found 9/7![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:05 am -
1 stop5h 34m
Tue 9/293:19 pm -
1 stop5h 27m
Deal found 9/2![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop4h 58m
Mon 10/266:25 pm -
1 stop4h 34m
Deal found 9/4![American Airlines logo]()
$354
One-way flights from Durham to ColumbiaSearch for one-way flight options from Durham to Columbia. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Durham to Columbia. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:44 pm -
1 stop5h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$268
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:05 pm -
2 stops8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:35 am -
3 stops34h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:05 pm -
3 stops46h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:35 pm -
3 stops43h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:05 am -
2 stops14h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:50 am -
3 stops12h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:00 am -
3 stops27h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:00 pm -
2 stops9h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:43 pm -
1 stop6h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$418
Find flight deals from Durham to Columbia
Keep the following information in mind while searching for Durham to Columbia flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $232 (Kiwi.com) |
Popular in | October |
Cheapest in | February |
Average price | $378 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Durham to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sat 10/3
6:00 am-9:56 am
1 stop4h 56m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$268
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Fri 10/2
5:44 pm-10:08 pm
1 stop5h 24m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$268
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Mon 11/23
11:24 am-10:58 pm
2 stops12h 34m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Mon 10/5
3:05 pm-10:55 pm
2 stops8h 50m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sat 10/3
7:05 am-8:33 pm
2 stops14h 28m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$310
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Thu 9/17
10:00 am-12:54 pm
3 stops27h 54m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$357
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sun 9/20
6:00 am-2:30 pm
2 stops9h 30m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$379
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sat 9/26
6:05 am-10:39 am
1 stop5h 34m
Columbia Regional
Tue 9/29
3:19 pm-9:46 pm
1 stop5h 27m
$388
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Sat 10/3
6:05 am-10:39 am
1 stop5h 34m
Columbia Regional
Sat 10/10
3:19 pm-11:59 pm
2 stops7h 40m
$414
RaleighColumbia
RDU Raleigh-Durham - COU Columbia Regional
RDUCOU
Raleigh-Durham
Fri 9/18
12:49 pm-8:46 pm
2 stops8h 57m
Columbia Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$424
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Durham to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Durham with our price prediction graph.
RDU-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to Columbia
DU8-COU
RDU-COU
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Durham to Columbia to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Overall
7.4
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.6
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Overall
7.4
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.6
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Overall
7.4
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.6
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Durham to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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Top 2 airlines flying from Durham to Columbia
Discover the top 2 airlines that operate flights from Durham to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$354 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$403 | FlexibilityNo cancel fee | On-time71% |