HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Chicago

$120+ Cheap flights from Santa Ana (SNA) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — CHI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Ana to Chicago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santa Ana J. Wayne/Orange Cnty to Chicago are usually found in August or September, booked 90 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Santa Ana to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$269
(United Airlines)

One-way from

$120
(CheapOair)

Popular in

December

Cheapest in

August

Average price

$348

Good round-trip deal

$351 or less

Good one-way deal

$235 or less
From Santa Ana J. Wayne/Orange Cnty to Chicago (CHI)
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals
Price to beat on a round-trip flight from Santa Ana J. Wayne/Orange Cnty to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Santa Ana J. Wayne/Orange Cnty to Chicago (CHI).
Search Deals

Find flight deals from Santa Ana to Chicago

Cheapest flights from Santa Ana to Chicago
Explore the most affordable flight options available from Santa Ana to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/101:48 pmSNA - ORD
Nonstop4h 11mUnited Airlines
Tue 10/144:20 pmORD - SNA
Nonstop4h 26mUnited Airlines
Deal found 9/15$269
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/242:15 pmSNA - RFD
1 stop27h 32mMultiple Airlines
Sun 9/288:37 pmRFD - SNA
1 stop17h 38mMultiple Airlines
Deal found 9/15$270
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/168:09 pmSNA - ORD
2 stops16h 32mSpirit Airlines
Mon 10/203:36 pmORD - SNA
2 stops8h 27mSpirit Airlines
Deal found 9/15$270
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:49 pmSNA - MDW
2 stops15h 37mFrontier
Fri 11/712:30 pmMDW - SNA
1 stop27h 05mFrontier
Deal found 9/15$271
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:45 amSNA - ORD
2 stops11h 18mSpirit Airlines
Wed 10/156:35 amORD - SNA
1 stop14h 39mSpirit Airlines
Deal found 9/15$271
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:45 amSNA - ORD
1 stop12h 03mSpirit Airlines
Sun 10/266:40 amORD - SNA
1 stop14h 34mSpirit Airlines
Deal found 9/14$272
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:07 pmSNA - ORD
Nonstop4h 05mUnited Airlines
Wed 11/197:10 amORD - SNA
1 stop7h 18mUnited Airlines
Deal found 9/14$273
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/241:18 pmSNA - ORD
1 stop6h 10mFrontier
Sun 9/286:00 amORD - SNA
1 stop7h 07mFrontier
Deal found 9/14$274
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:46 pmSNA - ORD
2 stops13h 58mSpirit Airlines
Sun 11/167:35 amORD - SNA
2 stops15h 24mSpirit Airlines
Deal found 9/15$275
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/98:09 pmSNA - ORD
2 stops16h 32mSpirit Airlines
Mon 10/136:35 amORD - SNA
1 stop14h 39mSpirit Airlines
Deal found 9/15$276
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:20 amSNA - MDW
1 stop6h 55mSouthwest
Wed 11/128:25 amMDW - SNA
1 stop6h 10mSouthwest
Deal found 9/15$277
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:25 pmSNA - ORD
1 stop29h 36mAlaska Airlines
Sun 11/168:05 amORD - SNA
Nonstop4h 37mAlaska Airlines
Deal found 9/15$277

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santa Ana to Chicago that are best for you.

Fly from

Santa Ana

Fly to

Chicago

Route

Depart

Return

Price

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Thu 11/13

10:30 am-4:35 pm

Nonstop4h 05m

Chicago O'Hare Intl

Sat 11/15

4:10 pm-6:47 pm

Nonstop4h 37m

$269

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Fri 10/10

1:48 pm-7:59 pm

Nonstop4h 11m

Chicago O'Hare Intl

Tue 10/14

5:01 am-9:17 am

1 stop6h 16m

$269

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Fri 10/31

11:05 am-11:50 pm

1 stop10h 45m

Chicago O'Hare Intl

Mon 11/3

7:37 am-2:15 pm

1 stop8h 38m

$273

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Wed 10/8

4:00 pm-12:54 am

1 stop6h 54m

Chicago O'Hare Intl

Thu 10/9

7:58 pm-10:30 pm

Nonstop4h 32m

$273

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Wed 11/12

7:15 am-5:18 pm

1 stop8h 03m

Chicago O'Hare Intl

Tue 12/2

2:14 pm-10:21 pm

1 stop10h 07m

$277

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Fri 11/14

1:50 pm-9:25 pm

1 stop5h 35m

Chicago O'Hare Intl

Tue 12/2

2:14 pm-10:21 pm

1 stop10h 07m

$283

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Mon 11/17

9:30 pm-8:41 am

1 stop9h 11m

Chicago O'Hare Intl

Tue 12/2

2:14 pm-10:21 pm

1 stop10h 07m

$283

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Fri 11/7

9:25 pm-5:01 am

1 stop29h 36m

Chicago O'Hare Intl

Sun 11/9

8:05 am-10:42 am

Nonstop4h 37m

$287

Santa AnaChicago

SNA - MDW

SNAMDW

Santa Ana J. Wayne/Orange Cnty

Fri 11/14

9:10 pm-5:05 am

1 stop5h 55m

Chicago Midway

Wed 11/19

1:55 pm-8:15 pm

2 stops8h 20m

$288

Santa AnaChicago

SNA - ORD

SNAORD

Santa Ana J. Wayne/Orange Cnty

Wed 10/15

1:48 pm-7:59 pm

Nonstop4h 11m

Chicago O'Hare Intl

Wed 10/22

7:58 pm-10:30 pm

Nonstop4h 32m

$288

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 59 results
1
2
3
...
6

The best insider tips for Santa Ana to Chicago flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Santa Ana to Chicago trip
Airports
SNA

For shorter security lines, try "checkpoint shopping" at SNA. If one line is long, check the others for a quicker option.

Read more about SNAby Scott Laird
ORD

For a quick city transfer, consider taking the "L" train from ORD to downtown Chicago, avoiding potential traffic delays.

Read more about ORDby Ramsey Qubein
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on ORD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Scott Laird

Scott Laird

Expert on SNA

Scott Laird

Scott Laird

Originally from Anchorage, Alaska, Scott is a frequent contributor to Fodor’s Travel Guide, Conde Nast Traveler, TravelAge West, and TravelPulse. He holds a Bachelor of Science in Organizational Management from Alaska Pacific University and a Master of Science in Airline Management from Embry-Riddle Aeronautical University, and has worked in the airline and hotel industries and as a travel consultant.

Read more

Best time to book a flight from Santa Ana to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Chicago

How far ahead should I book a flight from Santa Ana to Chicago?

Use this chart to determine the optimal time to book a round-trip flight from Santa Ana to Chicago. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Santa Ana to Chicago, you should look to book at least 51 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santa Ana to Chicago?

Currently, August is the cheapest month in which you can book a flight from Santa Ana to Chicago (average of $245). Flying from Santa Ana to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to CHI?

Find hourly flight availability from Santa Ana to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Santa Ana to Chicago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 29% versus a flight in the morning.

What is the cheapest day to fly from Santa Ana to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Santa Ana to Chicago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Santa Ana to Chicago flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Santa Ana to Chicago

Explore weekly flight availability from Santa Ana to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from SNA to CHI are scheduled on a Thursday (28 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (20 on average).

How much does it cost to fly round-trip from Santa Ana to Chicago?

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Santa Ana to Chicago, such as Alaska Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,929 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Spirit Airlines
6.3
Okay
8,015 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,172 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Ana to Chicago?

    Most people fly from Santa Ana J. Wayne/Orange Cnty (SNA) if they book a flight from Santa Ana to Chicago. On average, J. Wayne/Orange Cnty has 24 outbound flights to Chicago per day from 6 airlines. Santa Ana J. Wayne/Orange Cnty is conveniently located just 4.8 mi from Santa Ana’s city center.

  • How long is the flight from Santa Ana to Chicago?

    There are many flights that can get you from Santa Ana to Chicago in 4h 05m. Fly via United Airlines, Delta, or Southwest to get the fastest option. There are 1721 mi between Santa Ana and Chicago. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Santa Ana to Chicago round-trip?

    Currently priced at $110, Frontier will fly you from Santa Ana to Chicago and back. In addition to Frontier, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Spirit Airlines and Alaska Airlines - these airlines can fly you to your destination from $117 and $190, respectively. Users have found that Frontier is 72% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Santa Ana to Chicago one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $120. However, be on the lookout for offers from Hawaiian Airlines and Alaska Airlines, as they are both options that can get you from Santa Ana to Chicago for a low price.

  • What are the most popular routes from Santa Ana to Chicago?

    The most popular route from Santa Ana to Chicago is Santa Ana J. Wayne/Orange Cnty - Chicago O'Hare Intl. You may also consider Santa Ana J. Wayne/Orange Cnty - Chicago Midway or Santa Ana J. Wayne/Orange Cnty - Chicago Greater Rockford.

  • What are the most reliable airlines from Santa Ana to Chicago?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Santa Ana to Chicago on time: Brussels Airlines (90%), Emirates (87%), United Airlines (84%).

  • What are the cheapest flights from Santa Ana to Chicago?

    Looking for the cheapest flight from Santa Ana to Chicago? While on average our users pay $933, our data indicates the cheapest price to be $160. The most popular route (Santa Ana J. Wayne/Orange Cnty - Chicago O'Hare Intl), is priced around $121.

  • Can I find deals for flights from Santa Ana to Chicago that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Chicago.

  • Can I find deals for business class flights from Santa Ana to Chicago?

    Yes. Cheapflights offers flight deals from Santa Ana to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Santa Ana to Chicago (average of $245). Flying from Santa Ana to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Chesterton

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to O'Hare Intl flights
San Francisco to O'Hare Intl flights
Ontario to O'Hare Intl flights
Los Angeles to Midway flights
Santa Ana to O'Hare Intl flights
San Diego to O'Hare Intl flights
San Francisco to Midway flights
Burbank to O'Hare Intl flights
San Jose to O'Hare Intl flights
Las Vegas to O'Hare Intl flights
Sacramento to O'Hare Intl flights
Oakland to O'Hare Intl flights
San Francisco to St. Louis flights
Ontario to Midway flights
Los Angeles to St. Louis flights
San Jose to Midway flights
Santa Ana to Midway flights
San Diego to Midway flights
Las Vegas to Midway flights
Palm Springs to O'Hare Intl flights
Reno to O'Hare Intl flights
Fresno to O'Hare Intl flights
Burbank to Midway flights
Ontario to St. Louis flights
Oakland to Midway flights
Las Vegas to St. Louis flights
Long Beach to O'Hare Intl flights
San Diego to St. Louis flights
Sacramento to Midway flights
Burbank to St. Louis flights
Reno to Midway flights
Long Beach to Midway flights
Sacramento to St. Louis flights
Santa Ana to St. Louis flights
Fresno to St. Louis flights
Santa Rosa to O'Hare Intl flights
San Jose to St. Louis flights
Reno to St. Louis flights
Fresno to Midway flights
Santa Barbara to O'Hare Intl flights
Long Beach to St. Louis flights
Los Angeles to Peoria flights
Santa Ana to Bloomington flights
Palm Springs to Midway flights
San Luis Obispo to O'Hare Intl flights
Santa Ana to Peoria flights
Monterey to O'Hare Intl flights
Ontario to Peoria flights
Los Angeles to Moline flights
Oakland to St. Louis flights

Top 6 airlines flying from Santa Ana to Chicago

Discover the top 6 airlines that operate flights from Santa Ana to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$110Average$283FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$117Average$200FlexibilityNo cancel feeOn-time65%
Alaska AirlinesCheapest$190Average$459FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$269Average$473FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$269Average$382FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$312Average$446FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.