$367+ Cheap flights from Panama to Charlotte (CLT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Charlotte
Cheapest
Best
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Cheapest flights from Panama to CharlotteExplore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:00 am -
1 stop30h 53m
Tue 1/56:30 am -
1 stop10h 42m
Deal found 9/7![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:02 pm -
1 stop17h 23m
Tue 11/1710:25 pm -
1 stop15h 48m
Deal found 9/6![American Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:00 am -
2 stops13h 44m
Sun 1/106:30 am -
1 stop8h 15m
Deal found 9/7![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:41 pm -
1 stop23h 03m
Sat 1/28:07 am -
2 stops21h 03m
Deal found 9/7![United Airlines logo]()
$637
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:01 am -
1 stop11h 54m
Fri 10/239:40 pm -
1 stop11h 50m
Deal found 9/9![Multiple Airlines logo]()
$655
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:45 am -
2 stops27h 35m
Tue 1/197:47 pm -
2 stops21h 25m
Deal found 9/8![United Airlines logo]()
$659
This KAYAK deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:55 am -
1 stop13h 04m
Tue 12/16:00 am -
1 stop14h 02m
Deal found 9/9![Copa Airlines logo]()
$663
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1811:35 am -
1 stop12h 24m
Sun 1/106:30 am -
1 stop10h 42m
Deal found 9/7![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:55 am -
2 stops15h 04m
Thu 1/77:47 pm -
2 stops21h 25m
Deal found 9/7![United Airlines logo]()
$669
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:55 pm -
2 stops20h 56m
Thu 12/316:00 am -
2 stops11h 12m
Deal found 9/9![United Airlines logo]()
$679
This BusinessClass deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:13 pm -
1 stop16h 59m
Sun 11/87:30 pm -
1 stop18h 43m
Deal found 9/7![GOL logo]()
$680
Best flights from Panama to CharlotteDiscover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:00 am -
1 stop11h 41m
Wed 12/26:00 am -
2 stops14h 02m
Deal found 9/9![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:00 am -
2 stops13h 44m
Thu 12/36:00 am -
2 stops14h 02m
Deal found 9/8![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:55 am -
1 stop12h 57m
Sun 2/284:45 pm -
1 stop26h 53m
Deal found 9/5![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:55 pm -
1 stop22h 04m
Thu 12/316:20 am -
1 stop13h 18m
Deal found 9/9![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:55 am -
2 stops25h 47m
Thu 11/1910:52 am -
1 stop9h 10m
Deal found 9/9![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/194:41 pm -
1 stop23h 11m
Mon 2/224:45 pm -
1 stop24h 27m
Deal found 9/9![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:55 am -
1 stop12h 56m
Tue 1/58:15 am -
2 stops11h 47m
Deal found 9/7![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 am -
1 stop11h 41m
Wed 12/26:00 am -
1 stop14h 02m
Deal found 9/9![United Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:41 pm -
1 stop23h 03m
Sat 1/28:07 am -
2 stops21h 03m
Deal found 9/9![United Airlines logo]()
$637
Last-minute flights from Panama to CharlotteDiscover last-minute flight deals from Panama to Charlotte. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Charlotte. Data last updated September 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:23 pm -
1 stop8h 36m
Mon 9/145:30 am -
1 stop8h 28m
Deal found 9/7![Delta logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:30 pm -
1 stop29h 29m
Wed 11/257:55 pm -
2 stops24h 07m
Deal found 9/9![United Airlines logo]()
$679
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:01 am -
1 stop11h 54m
Fri 10/239:40 pm -
1 stop11h 50m
Deal found 9/9![Multiple Airlines logo]()
$655
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:01 am -
1 stop11h 54m
Fri 10/169:40 pm -
1 stop11h 50m
Deal found 9/9![Multiple Airlines logo]()
$734
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:02 pm -
2 stops15h 25m
Fri 10/236:00 am -
1 stop8h 02m
Deal found 9/9![American Airlines logo]()
$751
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:02 pm -
1 stop18h 45m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 9/9![American Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:30 pm -
1 stop23h 36m
Fri 10/305:33 pm -
2 stops26h 29m
Deal found 9/9![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:45 am -
2 stops27h 35m
Tue 1/197:47 pm -
2 stops21h 25m
Deal found 9/8![United Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:45 am -
1 stop24h 54m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/9![United Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:02 pm -
1 stop17h 23m
Tue 11/1710:25 pm -
1 stop15h 48m
Deal found 9/6![American Airlines logo]()
$613
One-way flights from Panama to CharlotteSearch for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:41 pm -
1 stop23h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:34 pm -
1 stop25h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:33 pm -
2 stops13h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:15 pm -
3 stops27h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$481
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:45 am -
2 stops27h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$546
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:30 am -
3 stops14h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$1,286
Find flight deals from Panama to Charlotte
Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $604 (United Airlines) |
One-way from | $367 (United Airlines) |
Popular in | March |
Cheapest in | December |
Average price | $702 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sat 11/21
4:41 pm-1:42 pm
2 stops21h 01m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$367
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sat 10/24
6:34 pm-8:55 pm
1 stop25h 21m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$420
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 10/6
9:45 am-2:20 pm
2 stops27h 35m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$546
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 11/17
10:00 am-9:41 pm
1 stop11h 41m
Charlotte Douglas
Wed 12/2
6:00 am-8:02 pm
2 stops14h 02m
$604
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 12/1
10:00 am-11:44 pm
2 stops13h 44m
Charlotte Douglas
Thu 12/3
6:00 am-8:02 pm
2 stops14h 02m
$604
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Mon 2/1
8:55 am-9:52 pm
1 stop12h 57m
Charlotte Douglas
Sun 2/28
4:45 pm-7:38 pm
1 stop26h 53m
$604
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Thu 12/17
11:55 pm-9:59 pm
1 stop22h 04m
Charlotte Douglas
Thu 12/31
6:20 am-7:38 pm
1 stop13h 18m
$604
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 11/4
8:55 am-10:42 am
2 stops25h 47m
Charlotte Douglas
Thu 11/19
10:52 am-8:02 pm
1 stop9h 10m
$604
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 1/19
4:41 pm-3:52 pm
1 stop23h 11m
Charlotte Douglas
Mon 2/22
4:45 pm-5:12 pm
1 stop24h 27m
$604
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 12/15
8:55 am-9:51 pm
1 stop12h 56m
Charlotte Douglas
Tue 1/5
8:15 am-8:02 pm
2 stops11h 47m
$604
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Panama to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
PTY-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Charlotte
PA0-CLT
PTY-CLT
What is the cheapest month to book a flight from Panama to Charlotte?
Currently, December is the cheapest month in which you can book a flight from Panama to Charlotte (average of $481). Flying from Panama to Charlotte in March is currently the most expensive (average of $771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated September 10, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Comfort
7.3
Food
6.7
Overall
7.4
Entertainment
7.1
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Comfort
7.3
Food
6.7
Overall
7.4
Entertainment
7.1
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Comfort
7.3
Food
6.7
Overall
7.4
Entertainment
7.1
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsRock Hill
Gastonia
Boone
Salisbury
Cornelius
Morganton
Mooresville
Huntersville
Matthews
Lancaster
Hickory
Shelby
Gaffney
Fort Mill
Statesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama to Charlotte
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Other flights to Charlotte
Explore flights to Charlotte departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Complete your trip
Complete your trip to Charlotte by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Charlotte by cabin class
Find flights from Panama to Charlotte, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Charlotte flights
Browse other Panama and Charlotte flight options. Last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama to Charlotte
Discover the top 2 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$425 | Average$706 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$584 | FlexibilityNo cancel fee | On-time71% |