$264+ Cheap flights from Panama to Charlotte (CLT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
May 12 — May 191
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Charlotte
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Cheapest flights from Panama to CharlotteExplore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:21 pm
PTY
- CLT
1 stop8h 36m
Delta
Mon 9/145:30 am
CLT
- PTY
1 stop8h 26m
Delta
Deal found 4/10![Delta logo]()
$465
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:40 pm
PTY
- CLT
1 stop17h 55m
American Airlines
Mon 9/149:00 pm
CLT
- PTY
1 stop18h 10m
American Airlines
Deal found 4/8![American Airlines logo]()
$471
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- CLT
1 stop8h 26m
Delta
Tue 6/166:59 am
CLT
- PTY
1 stop7h 10m
Delta
Deal found 4/11![Delta logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:30 am
PTY
- CLT
3 stops29h 15m
Multiple Airlines
Mon 6/1512:48 pm
CLT
- PTY
1 stop8h 49m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:33 pm
PTY
- CLT
1 stop18h 41m
Multiple Airlines
Wed 7/84:56 pm
CLT
- PTY
3 stops33h 59m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$506
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:10 pm
PTY
- CLT
2 stops19h 33m
Multiple Airlines
Sun 5/1712:48 pm
CLT
- PTY
3 stops14h 07m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$507
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:33 pm
PTY
- CLT
1 stop13h 10m
Multiple Airlines
Thu 5/1412:48 pm
CLT
- PTY
3 stops14h 07m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$521
Best flights from Panama to CharlotteDiscover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
Discover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- CLT
1 stop17h 19m
Delta
Mon 6/157:48 pm
CLT
- PTY
1 stop18h 21m
Delta
Deal found 4/11![Delta logo]()
$498
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:49 pm
PTY
- CLT
2 stops15h 37m
American Airlines
Tue 5/265:15 am
CLT
- PTY
1 stop7h 59m
American Airlines
Deal found 4/7![American Airlines logo]()
$575
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:33 pm
PTY
- CLT
1 stop13h 10m
Multiple Airlines
Sun 5/1712:48 pm
CLT
- PTY
1 stop7h 32m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:45 am
PTY
- CLT
2 stops13h 13m
United Airlines
Mon 9/146:00 am
CLT
- PTY
2 stops14h 31m
United Airlines
Deal found 4/7![United Airlines logo]()
$622
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:30 pm
PTY
- CLT
2 stops24h 41m
United Airlines
Tue 5/266:00 am
CLT
- PTY
2 stops14h 31m
United Airlines
Deal found 4/8![United Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:30 pm
PTY
- CLT
1 stop29h 29m
United Airlines
Wed 7/87:00 am
CLT
- PTY
1 stop10h 12m
United Airlines
Deal found 4/9![United Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:45 am
PTY
- CLT
2 stops13h 06m
United Airlines
Wed 6/106:00 am
CLT
- PTY
2 stops14h 31m
United Airlines
Deal found 4/11![United Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:00 am
PTY
- CLT
1 stop10h 59m
United Airlines
Sun 8/25:51 pm
CLT
- PTY
1 stop11h 13m
United Airlines
Deal found 4/8![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:30 pm
PTY
- CLT
2 stops24h 41m
United Airlines
Tue 5/128:05 am
CLT
- PTY
2 stops12h 26m
United Airlines
Deal found 4/7![United Airlines logo]()
$686
Last-minute flights from Panama to CharlotteDiscover last-minute flight deals from Panama to Charlotte. Data last updated April 12, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Charlotte. Data last updated April 12, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:10 am
PTY
- CLT
2 stops33h 39m
Multiple Airlines
Fri 4/246:30 am
CLT
- PTY
2 stops27h 45m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- CLT
1 stop8h 26m
Delta
Tue 6/166:59 am
CLT
- PTY
1 stop7h 10m
Delta
Deal found 4/11![Delta logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:30 am
PTY
- CLT
3 stops29h 15m
Multiple Airlines
Mon 6/1512:48 pm
CLT
- PTY
1 stop8h 49m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:25 am
PTY
- CLT
2 stops27h 45m
Multiple Airlines
Wed 6/106:33 pm
CLT
- PTY
1 stop14h 33m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$543
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:25 am
PTY
- CLT
2 stops27h 45m
Multiple Airlines
Tue 6/166:33 pm
CLT
- PTY
1 stop14h 33m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$554
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:33 pm
PTY
- CLT
1 stop13h 10m
Multiple Airlines
Thu 5/1412:48 pm
CLT
- PTY
3 stops14h 07m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$521
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:10 pm
PTY
- CLT
2 stops19h 33m
Multiple Airlines
Sun 5/1712:48 pm
CLT
- PTY
3 stops14h 07m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$507
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:33 pm
PTY
- CLT
1 stop13h 10m
Multiple Airlines
Mon 5/2512:48 pm
CLT
- PTY
1 stop7h 32m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$534
One-way flights from Panama to CharlotteSearch for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
Search for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:10 pm
PTY
- CLT
2 stops19h 33m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:40 pm
PTY
- CLT
1 stop15h 42m
American Airlines
Deal found 4/11![American Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:30 am
PTY
- CLT
3 stops31h 13m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:55 pm
PTY
- CLT
3 stops37h 10m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/183:10 pm
PTY
- CLT
2 stops19h 35m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:10 pm
PTY
- CLT
3 stops21h 29m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:10 pm
PTY
- CLT
3 stops29h 51m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$310
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:10 pm
PTY
- CLT
2 stops31h 30m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:30 am
PTY
- CLT
3 stops30h 44m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$322
Find flight deals from Panama to Charlotte
Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated April 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $465 (Delta) |
One-way from | $264 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $523 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Wed 4/29
2:27 pm-8:46 am
1 stop17h 19m
Charlotte Douglas
Mon 6/15
7:48 pm-1:09 pm
1 stop18h 21m
$498
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Tue 5/19
1:49 pm-6:26 am
2 stops15h 37m
Charlotte Douglas
Tue 5/26
5:15 am-12:14 pm
1 stop7h 59m
$575
Quickest round-trip
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 5/14
9:33 pm-11:43 am
1 stop13h 10m
Charlotte Douglas
Sun 5/17
12:48 pm-7:20 pm
1 stop7h 32m
$587
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 9/10
9:45 am-11:58 pm
2 stops13h 13m
Charlotte Douglas
Mon 9/14
6:00 am-7:31 pm
2 stops14h 31m
$622
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Tue 5/19
3:30 pm-5:11 pm
2 stops24h 41m
Charlotte Douglas
Tue 5/26
6:00 am-7:31 pm
2 stops14h 31m
$664
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Mon 6/8
3:30 pm-9:59 pm
1 stop29h 29m
Charlotte Douglas
Wed 7/8
7:00 am-4:12 pm
1 stop10h 12m
$664
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Wed 4/29
9:45 am-11:51 pm
2 stops13h 06m
Charlotte Douglas
Wed 6/10
6:00 am-7:31 pm
2 stops14h 31m
$664
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Fri 7/31
10:00 am-9:59 pm
1 stop10h 59m
Charlotte Douglas
Sun 8/2
5:51 pm-4:04 am
1 stop11h 13m
$673
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Mon 5/4
3:30 pm-5:11 pm
2 stops24h 41m
Charlotte Douglas
Tue 5/12
8:05 am-7:31 pm
2 stops12h 26m
$686
Cheapest one-way
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Fri 5/8
5:30 am-5:13 pm
2 stops10h 43m
$264
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Panama to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
PTY-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Charlotte
PA0-CLT
PTY-CLT
What is the cheapest month to book a flight from Panama to Charlotte?
Currently, December is the cheapest month in which you can book a flight from Panama to Charlotte (average of $295). Flying from Panama to Charlotte in January is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated April 12, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsRock Hill
Gastonia
Salisbury
Hickory
Morganton
Mooresville
Huntersville
Matthews
Boone
Lancaster
Shelby
Kannapolis
Gaffney
Fort Mill
Statesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
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Alternative routes for Panama to Charlotte
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charlotte
Explore flights to Charlotte departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 12, 2026.
Complete your trip
Complete your trip to Charlotte by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Charlotte by cabin class
Find flights from Panama to Charlotte, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Charlotte flights
Browse other Panama and Charlotte flight options. Last updated on April 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama to Charlotte
Discover the top 3 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$291 | Average$541 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$425 | Average$705 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$532 | FlexibilityNo cancel fee | On-time71% |