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$269+ Cheap flights from Panama to Charlotte (CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Cheap flight deals from Panama to Charlotte

Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$397
(Kiwi.com)

One-way from

$269
(Avianca Connect)

Popular in

October

Cheapest in

July

Average price

$523
Provider with most accurate pricing for Panama City Tocumen Intl-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charlotte Douglas flights.
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From Panama to Charlotte Douglas
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One-way flight from Panama to Charlotte Douglas
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Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Panama to Charlotte

Cheapest flights from Panama to Charlotte
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:46 pmPTY - CLT
1 stop7h 56mDelta
Wed 12/317:05 amCLT - PTY
1 stop12h 55mDelta
Deal found 11/21$424
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:50 pmPTY - CLT
2 stops15h 39mAmerican Airlines
Wed 12/318:57 amCLT - PTY
1 stop6h 57mAmerican Airlines
Deal found 11/21$434
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:50 pmPTY - CLT
1 stop8h 07mAmerican Airlines
Wed 12/105:15 amCLT - PTY
1 stop10h 27mAmerican Airlines
Deal found 11/24$475
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:50 pmPTY - CLT
1 stop18h 22mAmerican Airlines
Fri 1/95:15 amCLT - PTY
1 stop10h 23mAmerican Airlines
Deal found 11/23$488
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:00 amPTY - CLT
1 stop12h 19mDelta
Sat 1/36:00 amCLT - PTY
1 stop7h 57mDelta
Deal found 11/23$501
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:55 pmPTY - CLT
1 stop15h 16mAmerican Airlines
Sun 1/188:06 pmCLT - PTY
1 stop17h 21mAmerican Airlines
Deal found 11/23$504
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:25 amPTY - CLT
1 stop11h 44mMultiple Airlines
Wed 1/72:57 pmCLT - PTY
2 stops27h 58mMultiple Airlines
Deal found 11/24$508

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.

Fly from

Panama

Fly to

Charlotte

Route

Depart

Return

Price

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 1/21

9:33 pm-10:23 am

1 stop12h 50m

Charlotte Douglas

Sat 1/24

7:00 am-3:55 pm

1 stop8h 55m

$397

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 12/16

3:46 pm-11:42 pm

1 stop7h 56m

Charlotte Douglas

Wed 12/31

7:05 am-8:00 pm

1 stop12h 55m

$424

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 2/17

2:55 am-4:54 pm

2 stops13h 59m

Charlotte Douglas

Sun 2/22

7:00 am-1:00 am

2 stops18h 00m

$470

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 1/14

4:41 pm-3:42 pm

1 stop23h 01m

Charlotte Douglas

Tue 1/20

11:26 am-7:38 pm

1 stop8h 12m

$481

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 12/22

8:00 am-8:19 pm

1 stop12h 19m

Charlotte Douglas

Sat 1/3

8:15 am-8:00 pm

1 stop11h 45m

$501

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 1/21

2:55 am-6:01 pm

2 stops15h 06m

Charlotte Douglas

Tue 1/27

7:00 am-1:00 am

2 stops18h 00m

$501

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 12/29

8:25 am-8:09 pm

1 stop11h 44m

Charlotte Douglas

Wed 1/7

2:57 pm-6:55 pm

2 stops27h 58m

$508

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sun 12/21

4:55 pm-9:10 am

1 stop16h 15m

Charlotte Douglas

Sun 1/18

10:17 pm-1:27 pm

2 stops15h 10m

$509

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 2/18

2:50 pm-10:58 pm

1 stop8h 08m

Charlotte Douglas

Sun 2/22

6:20 am-1:50 pm

1 stop7h 30m

$512

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 12/1

2:55 pm-8:49 am

2 stops17h 54m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/21

Showing 1-10 of 13 results
1
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Best time to book a flight from Panama to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Charlotte

What is the cheapest month to book a flight from Panama to Charlotte?

Currently, June is the cheapest month in which you can book a flight from Panama to Charlotte (average of $209). Flying from Panama to Charlotte in February is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CLT?

Find hourly flight availability from Panama to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 24, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to Charlotte in the evening. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated November 24, 2025.
Read through reviews of airlines operating flights from Panama to Charlotte, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Entertainment

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Entertainment

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,037 reviews
Delta
7.9
Good
7,997 reviews

Entertainment

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
7,997 reviews

Entertainment

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charlotte from Panama?

    Charlotte Douglas (CLT), located 5.7 mi from the city center, is the airport you fly into when you book flights from Panama to Charlotte.

  • How long is the flight from Panama to Charlotte?

    Delta and United Airlines can get you from Panama to Charlotte in just under 7h 56m. Your travel time can differ by up to 15h 05m. Airlines will cover a distance of 1808 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Charlotte that include hotel bookings?

    Yes. In addition to deals on Panama to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Charlotte.

  • Can I find deals for business class flights from Panama to Charlotte?

    Yes. Cheapflights offers flight deals from Panama to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Charlotte?

    Currently, June is the cheapest month in which you can book a flight from Panama to Charlotte (average of $209). Flying from Panama to Charlotte in February is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Matthews
Gastonia
Salisbury
Hickory
Boone
Mooresville
Morganton
Huntersville
Lancaster
Rock Hill
Shelby
Kannapolis
Fort Mill
Pineville

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Charlotte

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to Charlotte

Discover the top 3 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$434Average$574FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$436Average$531FlexibilityNo cancel feeOn-time69%
DeltaCheapest$446Average$597FlexibilityNo cancel feeOn-timeN/A

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