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$228+ Cheap flights from Panama to Charlotte (CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
feb. 7 — feb. 141
sáb. 2/7
sáb. 2/14
1 adult, Economy
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Cheap flight deals from Panama to Charlotte

Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated enero 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$368
(Avianca Connect)

One-way from

$228
(Kiwi.com)

Popular in

October

Cheapest in

December

Average price

$554
Provider with most accurate pricing for Panama City Tocumen Intl-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charlotte Douglas flights.
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From Panama to Charlotte Douglas
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One-way flight from Panama to Charlotte Douglas
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Highest demand for flights based on searches. 5% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Panama to Charlotte

Cheapest flights from Panama to Charlotte
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 8, 2026.

This Avianca Connect deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/222:55 amPTY - CLT
2 stops15h 23mMultiple Airlines
jue. 2/265:55 amCLT - PTY
2 stops19h 05mMultiple Airlines
Deal found 1/6$368
This Mytrip deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/185:50 pmPTY - CLT
2 stops24h 28mMultiple Airlines
jue. 2/265:55 amCLT - PTY
2 stops19h 05mMultiple Airlines
Deal found 1/7$389
This Avianca Connect deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/92:55 amPTY - CLT
2 stops20h 01mMultiple Airlines
mar. 3/246:00 amCLT - PTY
2 stops20h 00mMultiple Airlines
Deal found 1/6$410
This Avianca Connect deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/92:55 amPTY - CLT
2 stops20h 01mMultiple Airlines
mar. 3/176:00 amCLT - PTY
2 stops20h 00mMultiple Airlines
Deal found 1/7$411
This Avianca Connect deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/82:55 amPTY - CLT
2 stops15h 53mMultiple Airlines
vie. 2/137:00 amCLT - PTY
2 stops17h 40mMultiple Airlines
Deal found 1/7$431
This Mytrip deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/125:50 pmPTY - CLT
2 stops30h 06mMultiple Airlines
vie. 2/205:55 amCLT - PTY
2 stops26h 55mMultiple Airlines
Deal found 1/8$434
This Avianca Connect deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/162:55 amPTY - CLT
2 stops16h 28mMultiple Airlines
mié. 4/17:00 amCLT - PTY
2 stops18h 45mMultiple Airlines
Deal found 1/6$456
This Avianca Connect deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/132:55 pmPTY - CLT
2 stops21h 25mMultiple Airlines
sáb. 2/217:00 amCLT - PTY
2 stops18h 00mMultiple Airlines
Deal found 1/7$462
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/109:45 amPTY - CLT
1 stop10h 48mUnited Airlines
lun. 9/144:45 pmCLT - PTY
1 stop26h 52mUnited Airlines
Deal found 1/8$482

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 8, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.

Fly from

Panama

Fly to

Charlotte

Route

Depart

Return

Price

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

dom. 2/22

2:55 am-6:18 pm

2 stops15h 23m

Charlotte Douglas

jue. 2/26

5:55 am-1:00 am

2 stops19h 05m

$368

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

lun. 3/9

2:55 am-11:56 pm

2 stops20h 01m

Charlotte Douglas

mar. 3/24

6:00 am-1:00 am

2 stops20h 00m

$410

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

lun. 3/9

2:55 am-11:56 pm

2 stops20h 01m

Charlotte Douglas

mar. 3/17

6:00 am-1:00 am

2 stops20h 00m

$411

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

dom. 2/8

2:55 am-6:48 pm

2 stops15h 53m

Charlotte Douglas

vie. 2/13

7:00 am-12:40 am

2 stops17h 40m

$431

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

lun. 3/16

2:55 am-8:23 pm

2 stops16h 28m

Charlotte Douglas

mar. 4/7

7:00 am-9:10 pm

2 stops15h 10m

$431

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mié. 2/18

5:50 pm-11:59 pm

3 stops30h 09m

Charlotte Douglas

jue. 2/26

5:55 am-1:00 am

2 stops19h 05m

$453

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

lun. 3/16

2:55 am-8:23 pm

2 stops16h 28m

Charlotte Douglas

mié. 4/1

7:00 am-12:45 am

2 stops18h 45m

$456

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

vie. 2/13

2:55 pm-12:20 pm

2 stops21h 25m

Charlotte Douglas

sáb. 2/21

7:00 am-1:00 am

2 stops18h 00m

$462

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

mar. 3/10

3:41 pm-3:50 pm

1 stop23h 09m

Charlotte Douglas

mar. 3/17

6:23 am-1:45 pm

1 stop8h 22m

$482

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

sáb. 1/31

5:50 pm-9:47 pm

2 stops27h 57m

$228

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 18 results
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2

Best time to book a flight from Panama to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Charlotte

What is the cheapest month to book a flight from Panama to Charlotte?

Currently, June is the cheapest month in which you can book a flight from Panama to Charlotte (average of $209). Flying from Panama to Charlotte in February is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated enero 8, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,025 reviews
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,095 reviews
Delta
7.9
Good
8,025 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charlotte from Panama?

    Charlotte Douglas (CLT), located 5.7 mi from the city center, is the airport you fly into when you book flights from Panama to Charlotte.

  • What are the cheapest airlines to fly from Panama to Charlotte one-way?

    One-way options have recently been found by users for as low as $273 on American Airlines. Other airlines that offer cheap prices include Delta from $284 and United Airlines from $289 one-way.

  • Can I find deals for flights from Panama to Charlotte that include hotel bookings?

    Yes. In addition to deals on Panama to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Charlotte.

  • Can I find deals for business class flights from Panama to Charlotte?

    Yes. Cheapflights offers flight deals from Panama to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Charlotte?

    Currently, June is the cheapest month in which you can book a flight from Panama to Charlotte (average of $209). Flying from Panama to Charlotte in February is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Matthews
Gastonia
Salisbury
Hickory
Boone
Mooresville
Morganton
Huntersville
Lancaster
Rock Hill
Shelby
Kannapolis
Fort Mill

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Charlotte

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Charlotte

Discover the top 2 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$423Average$541FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$429Average$548FlexibilityNo cancel feeOn-time71%

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