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$254+ Cheap flights from Panama to Charlotte (CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Panama to Charlotte

Cheapest flights from Panama to Charlotte
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:21 pm
PTY
-
CLT
1 stop8h 36m
Delta
Mon 9/145:30 am
CLT
-
PTY
1 stop8h 26m
Delta
Deal found 4/28$465
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:40 pm
PTY
-
CLT
2 stops13h 47m
American Airlines
Mon 9/149:00 pm
CLT
-
PTY
1 stop18h 10m
American Airlines
Deal found 4/28$478
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:35 pm
PTY
-
CLT
1 stop14h 28m
American Airlines
Sun 11/18:19 pm
CLT
-
PTY
1 stop17h 17m
American Airlines
Deal found 4/27$508
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/203:40 pm
PTY
-
CLT
1 stop14h 28m
American Airlines
Sat 9/267:05 am
CLT
-
PTY
1 stop8h 05m
American Airlines
Deal found 4/27$533
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:33 pm
PTY
-
CLT
1 stop13h 10m
Multiple Airlines
Sun 5/3112:48 pm
CLT
-
PTY
1 stop7h 32m
Multiple Airlines
Deal found 4/24$559
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:10 am
PTY
-
CLT
1 stop8h 03m
Multiple Airlines
Tue 5/121:00 pm
CLT
-
PTY
2 stops20h 06m
Multiple Airlines
Deal found 4/28$563
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:49 pm
PTY
-
CLT
1 stop8h 08m
American Airlines
Tue 5/129:50 pm
CLT
-
PTY
1 stop15h 56m
American Airlines
Deal found 4/28$607

Find flight deals from Panama to Charlotte

Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$465
(Delta)

One-way from

$254
(Trip.com)

Popular in

March

Cheapest in

December

Average price

$523
Provider with most accurate pricing for Panama City Tocumen Intl-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charlotte Douglas flights.
Search Deals
From Panama to Charlotte Douglas
Search Deals
One-way flight from Panama to Charlotte Douglas
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/10

2:21 pm-11:57 pm

1 stop8h 36m

Charlotte Douglas

Mon 9/14

5:30 am-12:56 pm

1 stop8h 26m

$465

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sun 5/24

3:10 pm-11:43 am

2 stops19h 33m

Charlotte Douglas

Sun 5/31

9:07 pm-5:00 pm

3 stops44h 53m

$617

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/10

9:45 am-11:58 pm

2 stops13h 13m

Charlotte Douglas

Mon 9/14

2:59 pm-7:31 pm

2 stops29h 32m

$622

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sat 5/16

9:33 pm-5:13 pm

1 stop18h 40m

Charlotte Douglas

Sat 8/29

8:34 pm-2:55 pm

2 stops19h 21m

$641

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 7/24

7:55 am-9:59 pm

1 stop13h 04m

Charlotte Douglas

Tue 7/28

6:15 am-7:31 pm

2 stops14h 16m

$643

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 6/5

9:45 am-8:22 pm

1 stop9h 37m

Charlotte Douglas

Tue 7/7

7:00 am-2:14 pm

1 stop8h 14m

$664
Cheapest one-way

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 6/8

5:30 am-5:14 pm

3 stops34h 44m

$261
Quickest one-way

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 9/17

3:40 pm-6:27 am

2 stops13h 47m

$275

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sun 5/17

5:55 pm-2:11 pm

2 stops43h 16m

$302

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Sat 5/9

4:25 am-8:02 pm

2 stops14h 37m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Charlotte

What is the cheapest month to book a flight from Panama to Charlotte?

Currently, July is the cheapest month in which you can book a flight from Panama to Charlotte (average of $236). Flying from Panama to Charlotte in January is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated April 29, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,465 reviews

Boarding

8.1

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,465 reviews
Delta
7.9
Good
8,465 reviews

Boarding

8.1

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,678 reviews
Delta
7.9
Good
8,465 reviews

Boarding

8.1

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charlotte from Panama?

    Charlotte Douglas (CLT), located 5.7 mi from the city center, is the airport you fly into when you book flights from Panama to Charlotte.

  • How long is the flight from Panama to Charlotte?

    Delta can get you from Panama to Charlotte in just under 8h 36m. Your travel time can differ by up to . Airlines will cover a distance of 1808 mi.

  • Can I find deals for flights from Panama to Charlotte that include hotel bookings?

    Yes. In addition to deals on Panama to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Charlotte.

  • Can I find deals for business class flights from Panama to Charlotte?

    Yes. Cheapflights offers flight deals from Panama to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Charlotte?

    Currently, July is the cheapest month in which you can book a flight from Panama to Charlotte (average of $236). Flying from Panama to Charlotte in January is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Rock Hill
Hickory
Gastonia
Salisbury
Morganton
Mooresville
Huntersville
Matthews
Boone
Lancaster
Shelby
Kannapolis
Gaffney
Fort Mill
Statesville

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama to Charlotte

Discover the top 2 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$291Average$541FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$429Average$532FlexibilityNo cancel feeOn-time71%

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