$476+ Cheap flights from Panama to Charlotte (CLT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Charlotte
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to CharlotteExplore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:55 pm -
2 stops20h 56m
Sat 1/26:00 am -
1 stop23h 10m
Deal found 8/25![United Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
1 stop23h 36m
Mon 10/197:00 am -
1 stop13h 31m
Deal found 8/26![United Airlines logo]()
$648
This Trip.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:55 pm -
2 stops19h 00m
Sun 9/2011:27 am -
3 stops15h 28m
Deal found 8/23![Multiple Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:39 pm -
1 stop19h 16m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 8/22![American Airlines logo]()
$666
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:16 pm -
1 stop20h 43m
Thu 10/157:47 pm -
1 stop18h 15m
Deal found 8/26![American Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops17h 54m
Fri 10/305:33 pm -
2 stops26h 29m
Deal found 8/26![United Airlines logo]()
$680
Best flights from Panama to CharlotteDiscover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:35 am -
1 stop23h 11m
Sat 1/26:00 am -
2 stops23h 10m
Deal found 8/26![United Airlines logo]()
$626
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
1 stop13h 37m
Sat 1/29:50 am -
1 stop10h 10m
Deal found 8/25![Delta logo]()
$626
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2211:35 am -
1 stop12h 24m
Sun 1/310:50 am -
1 stop18h 20m
Deal found 8/23![United Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops17h 54m
Fri 10/305:33 pm -
2 stops26h 29m
Deal found 8/26![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops17h 54m
Wed 9/307:50 pm -
2 stops24h 41m
Deal found 8/23![United Airlines logo]()
$703
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops21h 32m
Wed 10/149:54 am -
1 stop10h 37m
Deal found 8/26![United Airlines logo]()
$703
Last-minute flights from Panama to CharlotteDiscover last-minute flight deals from Panama to Charlotte. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Charlotte. Data last updated August 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:39 pm -
1 stop19h 16m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 8/22![American Airlines logo]()
$666
This Trip.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:55 pm -
2 stops19h 00m
Sun 9/2011:27 am -
3 stops15h 28m
Deal found 8/23![Multiple Airlines logo]()
$662
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops24h 47m
Wed 10/219:54 am -
1 stop10h 37m
Deal found 8/26![United Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:16 pm -
1 stop20h 43m
Thu 10/157:47 pm -
1 stop18h 15m
Deal found 8/26![American Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops17h 54m
Fri 10/305:33 pm -
2 stops26h 29m
Deal found 8/26![United Airlines logo]()
$680
One-way flights from Panama to CharlotteSearch for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:25 am -
1 stop26h 30m
Deal found 8/22![Multiple Airlines logo]()
$476
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:00 am -
2 stops27h 08m
Deal found 8/22![Multiple Airlines logo]()
$491
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:15 pm -
1 stop25h 59m
Deal found 8/22![Multiple Airlines logo]()
$493
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:34 am -
3 stops51h 07m
Deal found 8/24![Multiple Airlines logo]()
$504
This oojo deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 am -
2 stops36h 26m
Deal found 8/22![Avianca logo]()
$524
This Avianca deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 am -
2 stops12h 26m
Deal found 8/23![Avianca logo]()
$526
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:55 pm -
1 stop20h 49m
Deal found 8/23![United Airlines logo]()
$541
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:45 pm -
3 stops38h 28m
Deal found 8/23![Multiple Airlines logo]()
$554
Find flight deals from Panama to Charlotte
Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $626 (United Airlines) |
One-way from | $476 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $647 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/23
11:35 am-10:46 am
1 stop23h 11m
Charlotte Douglas
Sat 1/2
6:00 am-5:10 am
2 stops23h 10m
$626
Quickest round-trip
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/23
8:00 am-9:37 pm
1 stop13h 37m
Charlotte Douglas
Sat 1/2
9:50 am-8:00 pm
1 stop10h 10m
$626
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 12/22
11:35 am-11:59 pm
1 stop12h 24m
Charlotte Douglas
Sun 1/3
10:50 am-5:10 am
1 stop18h 20m
$626
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 9/9
3:30 pm-10:24 am
2 stops17h 54m
Charlotte Douglas
Fri 10/30
5:33 pm-7:02 pm
2 stops26h 29m
$680
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 9/9
3:30 pm-10:24 am
2 stops17h 54m
Charlotte Douglas
Wed 9/30
7:50 pm-7:31 pm
2 stops24h 41m
$703
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 9/9
3:30 pm-2:02 pm
2 stops21h 32m
Charlotte Douglas
Wed 10/14
9:54 am-7:31 pm
1 stop10h 37m
$703
Cheapest one-way
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 9/22
10:25 am-1:55 pm
1 stop26h 30m
$476
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sat 9/19
10:00 am-2:08 pm
2 stops27h 08m
$491
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sun 9/20
6:15 pm-9:14 pm
1 stop25h 59m
$493
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sun 9/6
10:34 am-2:41 pm
3 stops51h 07m
$504
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Panama to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
PTY-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Charlotte
PA0-CLT
PTY-CLT
What is the cheapest month to book a flight from Panama to Charlotte?
Currently, December is the cheapest month in which you can book a flight from Panama to Charlotte (average of $489). Flying from Panama to Charlotte in March is currently the most expensive (average of $771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated August 26, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsRock Hill
Gastonia
Boone
Salisbury
Cornelius
Morganton
Mooresville
Huntersville
Matthews
Lancaster
Hickory
Shelby
Gaffney
Fort Mill
Statesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama to Charlotte
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charlotte
Explore flights to Charlotte departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Complete your trip
Complete your trip to Charlotte by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Charlotte by cabin class
Find flights from Panama to Charlotte, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Charlotte flights
Browse other Panama and Charlotte flight options. Last updated on August 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama to Charlotte
Discover the top 2 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$425 | Average$706 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$584 | FlexibilityNo cancel fee | On-time71% |