$330+ Cheap flights from Panama to Charlotte (CLT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Charlotte
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to CharlotteExplore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Trip.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:10 am -
2 stops26h 45m
Tue 10/69:59 pm -
2 stops17h 16m
Deal found 8/30![Multiple Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:35 am -
1 stop23h 11m
Sat 1/26:20 am -
1 stop13h 18m
Deal found 8/28![United Airlines logo]()
$626
This Trip.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:25 am -
2 stops15h 49m
Fri 10/309:41 pm -
2 stops28h 39m
Deal found 8/28![Multiple Airlines logo]()
$644
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
1 stop18h 24m
Tue 11/106:11 pm -
1 stop25h 51m
Deal found 9/1![United Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
2 stops23h 23m
Wed 10/2110:25 am -
2 stops10h 06m
Deal found 8/30![United Airlines logo]()
$664
This Trip.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:55 pm -
2 stops19h 00m
Mon 11/29:41 pm -
2 stops27h 39m
Deal found 9/1![Multiple Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:39 pm -
1 stop20h 20m
Thu 10/294:42 pm -
1 stop21h 20m
Deal found 9/1![American Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Fri 8/281:39 pm -
1 stop18h 01m
Fri 10/307:09 am -
1 stop6h 53m
Deal found 8/27![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:16 pm -
1 stop18h 03m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 8/28![American Airlines logo]()
$670
Best flights from Panama to CharlotteDiscover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Panama to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:55 pm -
2 stops20h 56m
Sat 1/26:00 am -
2 stops23h 10m
Deal found 8/31![United Airlines logo]()
$626
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
1 stop8h 09m
Sat 1/27:30 am -
1 stop12h 30m
Deal found 8/31![Delta logo]()
$626
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:00 am -
2 stops23h 33m
Sat 12/57:50 pm -
2 stops21h 22m
Deal found 8/29![United Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
2 stops23h 23m
Wed 10/2110:25 am -
2 stops10h 06m
Deal found 8/30![United Airlines logo]()
$664
Last-minute flights from Panama to CharlotteDiscover last-minute flight deals from Panama to Charlotte. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Charlotte. Data last updated September 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:39 pm -
1 stop20h 20m
Thu 10/294:42 pm -
1 stop21h 20m
Deal found 9/1![American Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
1 stop18h 24m
Tue 11/106:11 pm -
1 stop25h 51m
Deal found 9/1![United Airlines logo]()
$648
This Trip.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:55 pm -
2 stops19h 00m
Mon 11/29:41 pm -
2 stops27h 39m
Deal found 9/1![Multiple Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:16 pm -
1 stop18h 03m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 8/28![American Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm -
2 stops17h 54m
Fri 10/305:33 pm -
2 stops26h 29m
Deal found 8/28![United Airlines logo]()
$680
This Trip.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:25 am -
2 stops15h 49m
Fri 10/309:41 pm -
2 stops28h 39m
Deal found 8/28![Multiple Airlines logo]()
$644
This Trip.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:10 am -
2 stops26h 45m
Tue 10/69:59 pm -
2 stops17h 16m
Deal found 8/30![Multiple Airlines logo]()
$591
One-way flights from Panama to CharlotteSearch for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Panama to Charlotte. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:55 am -
2 stops14h 49m
Deal found 8/30![United Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:33 pm -
1 stop15h 22m
Deal found 8/31![Multiple Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/78:40 am -
3 stops49h 57m
Deal found 8/29![Multiple Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:46 am -
3 stops48h 15m
Deal found 8/29![Multiple Airlines logo]()
$527
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:45 am -
1 stop30h 15m
Deal found 8/28![United Airlines logo]()
$541
This Mytrip deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:30 am -
3 stops31h 40m
Deal found 8/30![Multiple Airlines logo]()
$648
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/155:30 am -
3 stops31h 20m
Deal found 8/30![Multiple Airlines logo]()
$755
Find flight deals from Panama to Charlotte
Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $591 (Trip.com) |
One-way from | $330 (United Airlines) |
Popular in | March |
Cheapest in | December |
Average price | $605 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/23
11:55 pm-8:51 pm
2 stops20h 56m
Charlotte Douglas
Sat 1/2
6:00 am-5:10 am
2 stops23h 10m
$626
Quickest round-trip
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/23
8:00 am-4:09 pm
1 stop8h 09m
Charlotte Douglas
Sat 1/2
7:30 am-8:00 pm
1 stop12h 30m
$626
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/2
10:00 am-9:33 am
2 stops23h 33m
Charlotte Douglas
Sat 12/5
7:50 pm-5:12 pm
2 stops21h 22m
$626
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 10/14
9:45 am-10:08 am
2 stops23h 23m
Charlotte Douglas
Wed 10/21
10:25 am-7:31 pm
2 stops10h 06m
$664
Cheapest one-way
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 12/15
10:00 am-9:06 am
1 stop23h 06m
$330
Quickest one-way
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/16
8:55 am-11:44 pm
2 stops14h 49m
$330
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 9/8
9:33 pm-1:55 pm
1 stop15h 22m
$489
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Mon 9/7
8:40 am-11:37 am
3 stops49h 57m
$495
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sun 9/6
6:46 am-8:01 am
3 stops48h 15m
$527
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 9/9
9:45 am-5:00 pm
1 stop30h 15m
$541
Sorted by cheapest first
Best time to book a flight from Panama to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
PTY-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Charlotte
PA0-CLT
PTY-CLT
What is the cheapest month to book a flight from Panama to Charlotte?
Currently, December is the cheapest month in which you can book a flight from Panama to Charlotte (average of $489). Flying from Panama to Charlotte in March is currently the most expensive (average of $771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated September 1, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Overall
7.4
Food
6.7
Crew
8.1
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Overall
7.4
Food
6.7
Crew
8.1
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Overall
7.4
Food
6.7
Crew
8.1
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsRock Hill
Gastonia
Boone
Salisbury
Cornelius
Morganton
Mooresville
Huntersville
Matthews
Lancaster
Hickory
Shelby
Gaffney
Fort Mill
Statesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama to Charlotte
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charlotte
Explore flights to Charlotte departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 1, 2026.
Complete your trip
Complete your trip to Charlotte by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Charlotte by cabin class
Find flights from Panama to Charlotte, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Charlotte flights
Browse other Panama and Charlotte flight options. Last updated on September 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama to Charlotte
Discover the top 2 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$425 | Average$706 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$584 | FlexibilityNo cancel fee | On-time71% |