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$243+ Cheap flights from Panama to Charlotte (CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
Mar 21 — Mar 281
Sat 3/21
Sat 3/28
1 adult, Economy
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Cheap flight deals from Panama to Charlotte

Cheapest flights from Panama to Charlotte
Explore the most affordable flight options available from Panama to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 19, 2026.

This Trip.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:55 pm
PTY
-
CLT
2 stops17h 52m
Multiple Airlines
Wed 4/110:55 am
CLT
-
PTY
2 stops28h 20m
Multiple Airlines
Deal found 2/17$407
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:49 pm
PTY
-
CLT
1 stop8h 08m
American Airlines
Mon 4/208:45 pm
CLT
-
PTY
1 stop17h 01m
American Airlines
Deal found 2/16$421
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:21 pm
PTY
-
CLT
1 stop8h 36m
Delta
Mon 9/145:30 am
CLT
-
PTY
1 stop8h 26m
Delta
Deal found 2/16$423
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:20 pm
PTY
-
CLT
2 stops14h 09m
American Airlines
Mon 8/3110:25 pm
CLT
-
PTY
1 stop16h 55m
American Airlines
Deal found 2/18$425
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:49 pm
PTY
-
CLT
1 stop9h 10m
American Airlines
Tue 5/126:10 am
CLT
-
PTY
1 stop7h 36m
American Airlines
Deal found 2/16$426
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:40 pm
PTY
-
CLT
1 stop6h 51m
American Airlines
Mon 9/148:15 pm
CLT
-
PTY
1 stop18h 55m
American Airlines
Deal found 2/18$428
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:10 am
PTY
-
CLT
2 stops13h 15m
Multiple Airlines
Sun 4/122:54 pm
CLT
-
PTY
1 stop18h 12m
Multiple Airlines
Deal found 2/18$437
This Avianca Connect deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:55 pm
PTY
-
CLT
2 stops20h 12m
Multiple Airlines
Wed 4/17:00 am
CLT
-
PTY
2 stops19h 05m
Multiple Airlines
Deal found 2/17$447

Find flight deals from Panama to Charlotte

Keep the following information in mind while searching for Panama to Charlotte flight deals. Data was last updated February 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$407
(Trip.com)

One-way from

$243
(American Airlines)

Popular in

October

Cheapest in

December

Average price

$573
Provider with most accurate pricing for Panama City Tocumen Intl-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charlotte Douglas flights.
Search Deals
From Panama to Charlotte Douglas
Search Deals
One-way flight from Panama to Charlotte Douglas
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from Panama to Charlotte that are best for you.

Fly from

Panama

Fly to

Charlotte

Route

Depart

Return

Price

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 3/24

2:55 pm-9:47 am

2 stops17h 52m

Charlotte Douglas

Wed 4/1

10:55 am-2:15 pm

2 stops28h 20m

$407

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 4/16

1:49 pm-10:57 pm

1 stop8h 08m

Charlotte Douglas

Mon 4/20

8:45 pm-12:46 pm

1 stop17h 01m

$421

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 5/5

1:49 pm-6:26 am

2 stops15h 37m

Charlotte Douglas

Tue 5/12

10:41 pm-12:46 pm

2 stops15h 05m

$431

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 4/8

10:10 am-12:25 am

2 stops13h 15m

Charlotte Douglas

Sun 4/12

2:54 pm-8:06 am

1 stop18h 12m

$437

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 3/18

2:55 pm-12:07 pm

2 stops20h 12m

Charlotte Douglas

Wed 4/1

7:00 am-1:05 am

2 stops19h 05m

$447

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 4/16

3:10 pm-1:43 pm

2 stops21h 33m

Charlotte Douglas

Mon 4/20

3:08 pm-8:06 am

1 stop17h 58m

$447

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 5/21

1:14 pm-12:41 am

1 stop10h 27m

$243

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 5/15

1:49 pm-10:57 pm

1 stop8h 08m

$243

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Mon 3/9

5:50 pm-12:20 pm

2 stops17h 30m

$245

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 3/11

2:55 pm-12:07 pm

2 stops20h 12m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/15

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Charlotte

What is the cheapest month to book a flight from Panama to Charlotte?

Currently, June is the cheapest month in which you can book a flight from Panama to Charlotte (average of $209). Flying from Panama to Charlotte in February is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated February 19, 2026.
Read through reviews of airlines operating flights from Panama to Charlotte, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,212 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,212 reviews
Delta
7.9
Good
8,212 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,321 reviews
Delta
7.9
Good
8,212 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,313 reviews
Delta
7.9
Good
8,212 reviews

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charlotte from Panama?

    Charlotte Douglas (CLT), located 5.7 mi from the city center, is the airport you fly into when you book flights from Panama to Charlotte.

  • How long is the flight from Panama to Charlotte?

    American Airlines can get you from Panama to Charlotte in just under 8h 08m. Your travel time can differ by up to . Airlines will cover a distance of 1808 mi.

  • What are the cheapest airlines to fly from Panama to Charlotte one-way?

    One-way options have recently been found by users for as low as $273 on American Airlines. Other airlines that offer cheap prices include Delta from $284 and United Airlines from $289 one-way.

  • Can I find deals for flights from Panama to Charlotte that include hotel bookings?

    Yes. In addition to deals on Panama to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Charlotte.

  • Can I find deals for business class flights from Panama to Charlotte?

    Yes. Cheapflights offers flight deals from Panama to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Charlotte?

    Currently, June is the cheapest month in which you can book a flight from Panama to Charlotte (average of $209). Flying from Panama to Charlotte in February is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Gaffney
Matthews
Gastonia
Salisbury
Hickory
Morganton
Mooresville
Huntersville
Boone
Rock Hill
Lancaster
Shelby
Kannapolis
Fort Mill
Statesville

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Panama to Charlotte

Discover the top 3 airlines that operate flights from Panama to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$291Average$541FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$425Average$645FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$434Average$548FlexibilityNo cancel feeOn-time71%

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