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Charleston

$79+ Cheap flights from Missouri to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Find flight deals from Missouri to Charleston

Cheapest flights from Missouri to Charleston
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:30 pmSTL - CHS
1 stop16h 07mMultiple Airlines
Fri 12/129:49 pmCHS - STL
2 stops36h 58mMultiple Airlines
Deal found 11/18$187
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:30 pmSTL - CHS
1 stop16h 07mMultiple Airlines
Fri 12/511:55 amCHS - STL
2 stops23h 19mMultiple Airlines
Deal found 11/18$204
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:04 pmSTL - CHS
2 stops21h 56mMultiple Airlines
Mon 12/83:33 pmCHS - STL
1 stop8h 00mMultiple Airlines
Deal found 11/18$219
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:30 pmSTL - CHS
1 stop16h 07mMultiple Airlines
Sun 12/72:59 pmCHS - STL
1 stop19h 00mMultiple Airlines
Deal found 11/17$247
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmMCI - CHS
2 stops18h 13mSpirit Airlines
Thu 12/119:49 pmCHS - MCI
1 stop21h 07mSpirit Airlines
Deal found 11/18$251
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:37 amSGF - CHS
1 stop5h 29mAmerican Airlines
Wed 12/316:27 pmCHS - SGF
1 stop4h 37mAmerican Airlines
Deal found 11/17$255
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:13 pmMCI - CHS
2 stops21h 47mMultiple Airlines
Mon 12/83:33 pmCHS - MCI
1 stop8h 42mMultiple Airlines
Deal found 11/17$258
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:01 pmMCI - CHS
2 stops26h 58mMultiple Airlines
Mon 12/153:33 pmCHS - MCI
1 stop8h 42mMultiple Airlines
Deal found 11/16$270
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:31 pmMCI - CHS
1 stop24h 23mMultiple Airlines
Sun 12/79:49 pmCHS - MCI
2 stops15h 02mMultiple Airlines
Deal found 11/17$278
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/34:08 pmSGF - CHS
1 stop6h 42mDelta
Sun 12/75:25 amCHS - SGF
1 stop6h 25mDelta
Deal found 11/18$279
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmMCI - CHS
1 stop16h 10mMultiple Airlines
Thu 12/119:49 pmCHS - MCI
1 stop21h 07mMultiple Airlines
Deal found 11/18$284
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:25 pmSGF - CHS
2 stops7h 48mAmerican Airlines
Sun 12/76:40 amCHS - SGF
1 stop4h 58mAmerican Airlines
Deal found 11/18$284

Cheap flight deals from Missouri to Charleston

Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$187
(Kiwi.com)

One-way from

$79
(Kiwi.com)

Popular in

May

Cheapest in

August

Average price

$392
Provider with most accurate pricing for Lambert-St Louis-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Charleston flights.
Search Deals
From Missouri to Charleston
Search Deals
One-way flight from Missouri to Charleston
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.

Fly from

Missouri

Fly to

Charleston

Route

Depart

Return

Price

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Thu 1/8

11:26 am-5:36 pm

1 stop29h 10m

Charleston

Sun 1/11

6:31 pm-10:31 am

1 stop17h 00m

$190

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Wed 1/7

6:15 pm-5:36 pm

1 stop22h 21m

Charleston

Sun 1/11

6:31 pm-10:31 am

1 stop17h 00m

$190

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Fri 1/23

4:29 pm-10:34 pm

1 stop5h 05m

Charleston

Sun 1/25

9:13 am-4:14 pm

1 stop8h 01m

$239

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Thu 1/22

12:45 pm-7:02 pm

1 stop5h 17m

Charleston

Sun 1/25

7:32 am-12:14 pm

1 stop5h 42m

$239

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Wed 12/3

7:43 pm-8:37 am

2 stops11h 54m

Charleston

Sun 12/7

2:59 pm-8:59 am

1 stop19h 00m

$248

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Thu 12/25

5:37 am-12:06 pm

1 stop5h 29m

Charleston

Wed 12/31

6:27 pm-10:04 pm

1 stop4h 37m

$255

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Fri 12/5

12:13 pm-11:00 am

2 stops21h 47m

Charleston

Mon 12/8

3:33 pm-11:15 pm

1 stop8h 42m

$258

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

Sat 1/24

6:00 am-12:05 pm

1 stop5h 05m

Charleston

Wed 1/28

10:31 am-4:15 pm

1 stop6h 44m

$259

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 2/17

7:10 am-11:47 am

1 stop3h 37m

Charleston

Fri 2/20

7:00 pm-11:38 pm

1 stop5h 38m

$267

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

Fri 12/12

7:01 pm-10:59 pm

2 stops26h 58m

Charleston

Mon 12/15

3:33 pm-11:15 pm

1 stop8h 42m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 57 results
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Best time to book a flight from Missouri to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Charleston

What is the cheapest month to book a flight from Missouri to Charleston?

Currently, February is the cheapest month in which you can book a flight from Missouri to Charleston (average of $84). Flying from Missouri to Charleston in December is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CHS?

Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 19, 2025.

It’s typically best to fly out from Missouri to Charleston in the evening. Doing so could potentially save you 23% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Charleston?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Charleston. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Charleston flight should consider departing on Saturday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Missouri?

    If you book a flight to Charleston from Missouri, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How popular is this Missouri to Charleston flight route?

    This flight path from Missouri to Charleston was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Charleston?

    Spirit Airlines, American Airlines, and Delta can get you from Missouri to Charleston in just under 3h 37m. Your travel time can differ by up to 25h 33m. The distance from Missouri to Charleston is about 705 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Charleston?

    When deciding which route to take from Missouri to Charleston consider Lambert-St Louis - Charleston, Kansas City - Charleston or Springfield-Branson - Charleston as they are the most popular.

  • Can I find deals for flights from Missouri to Charleston that include hotel bookings?

    Yes. In addition to deals on Missouri to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Charleston.

  • Can I find deals for business class flights from Missouri to Charleston?

    Yes. Cheapflights offers flight deals from Missouri to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Charleston?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Charleston (average of $84). Flying from Missouri to Charleston in December is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Santee
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Alternative routes for Missouri to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Charleston

Discover the top 3 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$370FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$237Average$401FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$248Average$391FlexibilityNo cancel feeOn-time71%

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