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Charleston

$114+ Cheap flights from Missouri to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
abr 16 — abr 231
qui 4/16
qui 4/23
1 adult, Economy
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Cheap flight deals from Missouri to Charleston

Cheapest flights from Missouri to Charleston
Explore the most affordable flight options available from Missouri to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on março 17, 2026.

This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/1411:42 am
STL
-
CHS
1 stop6h 10m
Delta
ter 4/217:25 am
CHS
-
STL
1 stop4h 09m
Delta
Deal found 3/11$227
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 4/45:15 pm
STL
-
CHS
Nonstop1h 55m
Southwest
qua 4/83:40 pm
CHS
-
STL
Nonstop2h 20m
Southwest
Deal found 3/12$231
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/1412:05 pm
STL
-
CHS
Nonstop1h 55m
Southwest
qua 4/223:40 pm
CHS
-
STL
Nonstop2h 20m
Southwest
Deal found 3/16$239
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/71:45 pm
STL
-
CHS
1 stop6h 20m
Southwest
ter 4/143:40 pm
CHS
-
STL
Nonstop2h 20m
Southwest
Deal found 3/16$249
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 4/312:24 pm
MCI
-
CHS
1 stop8h 49m
Spirit Airlines
ter 4/78:07 am
CHS
-
MCI
1 stop28h 22m
Spirit Airlines
Deal found 3/12$251
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 4/49:16 am
STL
-
CHS
2 stops8h 48m
United Airlines
qua 4/86:00 am
CHS
-
STL
1 stop5h 28m
United Airlines
Deal found 3/12$251
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 4/45:15 pm
STL
-
CHS
Nonstop1h 55m
Southwest
seg 4/68:55 pm
CHS
-
STL
1 stop4h 10m
Southwest
Deal found 3/12$255
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 4/156:30 am
STL
-
CHS
2 stops7h 23m
United Airlines
sáb 4/182:53 pm
CHS
-
STL
2 stops7h 20m
United Airlines
Deal found 3/11$256
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 4/81:29 pm
STL
-
CHS
1 stop7h 57m
American Airlines
sáb 4/117:07 am
CHS
-
STL
1 stop5h 40m
American Airlines
Deal found 3/16$259
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 4/612:24 pm
MCI
-
CHS
1 stop8h 49m
Spirit Airlines
qua 4/88:07 am
CHS
-
MCI
1 stop28h 22m
Spirit Airlines
Deal found 3/15$279
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 4/112:24 pm
MCI
-
CHS
1 stop8h 49m
Spirit Airlines
qua 4/88:07 am
CHS
-
MCI
2 stops16h 46m
Spirit Airlines
Deal found 3/14$287
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 4/112:24 pm
MCI
-
CHS
1 stop8h 49m
Multiple Airlines
seg 4/68:28 pm
CHS
-
MCI
2 stops40h 01m
Multiple Airlines
Deal found 3/12$315

Find flight deals from Missouri to Charleston

Keep the following information in mind while searching for Missouri to Charleston flight deals. Data was last updated março 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$231
(Southwest)

One-way from

$114
(American Airlines)

Popular in

May

Cheapest in

August

Average price

$430

Good round-trip deal

$393 or less
Provider with most accurate pricing for Lambert-St Louis-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Charleston flights.
Search Deals
From Missouri to Charleston
Search Deals
One-way flight from Missouri to Charleston
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Missouri to Charleston.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated março 17, 2026.
Use the filters below to find and compare flights from Missouri to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

ter 4/14

11:42 am-6:52 pm

1 stop6h 10m

Charleston

ter 4/21

7:25 am-10:34 am

1 stop4h 09m

$227

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

ter 5/12

12:05 pm-3:00 pm

Nonstop1h 55m

Charleston

sáb 5/16

12:40 pm-8:00 pm

2 stops8h 20m

$254

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

ter 5/12

7:45 am-1:51 pm

1 stop5h 06m

Charleston

qua 5/13

9:40 am-4:39 pm

1 stop7h 59m

$292

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

qua 4/15

2:30 pm-8:00 pm

1 stop4h 30m

Charleston

sáb 4/18

12:40 pm-7:10 pm

2 stops7h 30m

$307

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

qui 4/16

4:59 pm-8:43 am

1 stop14h 44m

Charleston

seg 4/20

8:28 pm-6:50 am

2 stops35h 22m

$332
Quickest round-trip

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

seg 6/8

2:20 pm-5:20 pm

Nonstop2h 00m

Charleston

sáb 6/13

4:50 pm-7:45 pm

1 stop3h 55m

$335

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

seg 4/13

6:15 am-2:53 pm

2 stops7h 38m

Charleston

qua 4/15

6:00 am-12:24 pm

2 stops7h 24m

$357

SpringfieldCharleston

SGF - CHS

SGFCHS

Springfield-Branson

seg 6/15

6:45 pm-11:57 pm

1 stop4h 12m

Charleston

seg 6/22

2:25 pm-6:10 pm

1 stop4h 45m

$374

JoplinCharleston

JLN - CHS

JLNCHS

Joplin

ter 8/25

8:42 am-5:46 pm

1 stop8h 04m

Charleston

sáb 8/29

4:26 pm-11:53 pm

1 stop8h 27m

$374

Kansas CityCharleston

MCI - CHS

MCICHS

Kansas City

sex 5/29

3:16 pm-9:51 pm

1 stop5h 35m

Charleston

qua 6/3

6:00 am-10:29 am

1 stop5h 29m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/15

Showing 1-10 of 58 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Charleston

What is the cheapest month to book a flight from Missouri to Charleston?

Currently, July is the cheapest month in which you can book a flight from Missouri to Charleston (average of $89). Flying from Missouri to Charleston in December is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CHS?

Find hourly flight availability from Missouri to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated março 17, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Charleston as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Missouri?

    If you book a flight to Charleston from Missouri, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How popular is this Missouri to Charleston flight route?

    This flight path from Missouri to Charleston was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Charleston?

    Delta, Southwest, and United Airlines can get you from Missouri to Charleston in just under 1h 55m. Your travel time can differ by up to 4h 15m. The distance from Missouri to Charleston is about 705 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Charleston one-way?

    One-way options have recently been found by users for as low as $98 on American Airlines. Other airlines that offer cheap prices include Delta from $105 and Southwest from $138 one-way.

  • What are the most popular routes from Missouri to Charleston?

    When deciding which route to take from Missouri to Charleston consider Lambert-St Louis - Charleston, Kansas City - Charleston or Springfield-Branson - Charleston as they are the most popular.

  • What are the cheapest flights from Missouri to Charleston?

    The cheapest flight price from Missouri to Charleston is $286. On average you can expect to pay $412. The most popular route, (Lambert-St Louis - Charleston), can usually be booked for $239.

  • Can I find deals for flights from Missouri to Charleston that include hotel bookings?

    Yes. In addition to deals on Missouri to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Charleston.

  • Can I find deals for business class flights from Missouri to Charleston?

    Yes. Cheapflights offers flight deals from Missouri to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Charleston?

    Currently, July is the cheapest month in which you can book a flight from Missouri to Charleston (average of $89). Flying from Missouri to Charleston in December is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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Baltimore to Charlotte flights
Denver to Savannah flights
Philadelphia to Savannah flights
LaGuardia to Greenville flights
Hobby to Charlotte flights
Minneapolis to Savannah flights
Reagan-National to Savannah flights
Newark to Columbia flights
Minneapolis to Charleston flights
George Bush Intcntl to Charlotte flights
Baltimore to Savannah flights
John F Kennedy Intl to Greenville flights
LaGuardia to Columbia flights
Seattle to Charlotte flights

Top 3 airlines flying from Missouri to Charleston

Discover the top 3 airlines that operate flights from Missouri to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated março 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$371FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$237Average$400FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$243Average$394FlexibilityNo cancel feeOn-time71%

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