$128+ Cheap flights from St. Louis (STL) to Central America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJO
Mar 14 — Mar 211
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Central America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Central America
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Central AmericaExplore the most affordable flight options available from St. Louis to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from St. Louis to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- GUA
2 stops14h 58m
Multiple Airlines
Wed 3/412:15 pm
GUA
- STL
1 stop10h 12m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:14 am
STL
- BZE
1 stop7h 04m
American Airlines
Tue 3/101:50 pm
BZE
- STL
1 stop9h 08m
American Airlines
Deal found 2/8![American Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:20 am
STL
- LIR
1 stop9h 20m
American Airlines
Fri 5/12:10 pm
LIR
- STL
1 stop17h 44m
American Airlines
Deal found 2/9![American Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- GUA
2 stops22h 11m
Multiple Airlines
Mon 3/911:15 am
GUA
- STL
1 stop11h 04m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:57 pm
STL
- LIR
1 stop17h 26m
American Airlines
Wed 3/2512:21 pm
LIR
- STL
2 stops19h 34m
American Airlines
Deal found 2/11![American Airlines logo]()
$357
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 am
STL
- LIR
1 stop8h 15m
LATAM Airlines
Mon 2/233:30 pm
LIR
- STL
1 stop17h 36m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:53 pm
STL
- SJO
1 stop17h 32m
American Airlines
Wed 5/2011:35 pm
SJO
- STL
1 stop17h 54m
American Airlines
Deal found 2/12![American Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:25 am
STL
- SJO
2 stops9h 35m
Southwest
Fri 5/19:00 am
SJO
- STL
1 stop13h 40m
Southwest
Deal found 2/11![Southwest logo]()
$361
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:02 am
STL
- LIR
1 stop7h 28m
American Airlines
Tue 12/153:28 pm
LIR
- STL
1 stop8h 31m
American Airlines
Deal found 2/9![American Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:54 pm
STL
- SAP
1 stop18h 10m
Multiple Airlines
Wed 4/1510:52 am
SAP
- STL
2 stops22h 38m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$366
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/223:49 pm
STL
- GUA
1 stop19h 31m
Multiple Airlines
Wed 3/412:15 pm
GUA
- STL
1 stop10h 12m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/164:13 pm
STL
- LIR
2 stops19h 57m
American Airlines
Mon 2/233:29 pm
LIR
- STL
2 stops18h 04m
American Airlines
Deal found 2/9![American Airlines logo]()
$367
Best flights from St. Louis to Central AmericaDiscover carefully curated flight deals from St. Louis to Central America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from St. Louis to Central America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
STL
- BZE
1 stop6h 16m
Delta
Tue 4/2812:41 pm
BZE
- STL
1 stop9h 53m
Delta
Deal found 2/8![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:15 am
STL
- BZE
1 stop8h 15m
Southwest
Wed 4/291:25 pm
BZE
- STL
1 stop7h 55m
Southwest
Deal found 2/11![Southwest logo]()
$341
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:24 am
STL
- LIR
1 stop8h 46m
American Airlines
Wed 5/1312:30 pm
LIR
- STL
1 stop8h 54m
American Airlines
Deal found 2/9![American Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:54 pm
STL
- SAP
1 stop18h 10m
Multiple Airlines
Wed 4/1510:52 am
SAP
- STL
2 stops22h 38m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$366
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
STL
- BZE
1 stop6h 15m
United Airlines
Tue 5/262:35 pm
BZE
- STL
2 stops17h 02m
United Airlines
Deal found 2/10![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:14 am
STL
- BZE
1 stop8h 36m
American Airlines
Tue 3/101:50 pm
BZE
- STL
2 stops18h 05m
American Airlines
Deal found 2/8![American Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:25 am
STL
- SJO
2 stops9h 35m
Southwest
Fri 5/19:00 am
SJO
- STL
1 stop13h 40m
Southwest
Deal found 2/11![Southwest logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/223:49 pm
STL
- GUA
2 stops20h 35m
Multiple Airlines
Wed 3/412:15 pm
GUA
- STL
1 stop10h 12m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:46 am
STL
- BZE
2 stops9h 44m
American Airlines
Tue 4/283:31 pm
BZE
- STL
2 stops20h 51m
American Airlines
Deal found 2/8![American Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:10 am
STL
- SJO
1 stop14h 52m
Delta
Sat 3/73:46 pm
SJO
- STL
1 stop7h 50m
Delta
Deal found 2/11![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
STL
- PTY
1 stop12h 38m
United Airlines
Tue 3/313:30 pm
PTY
- STL
1 stop17h 55m
United Airlines
Deal found 2/9![United Airlines logo]()
$415
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:46 am
STL
- BZE
2 stops9h 44m
American Airlines
Wed 4/291:52 pm
BZE
- STL
2 stops17h 38m
American Airlines
Deal found 2/11![American Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:30 am
STL
- SJO
1 stop7h 40m
Southwest
Fri 5/299:00 am
SJO
- STL
1 stop13h 40m
Southwest
Deal found 2/10![Southwest logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:47 am
STL
- GUA
1 stop27h 33m
Multiple Airlines
Mon 3/911:15 am
GUA
- STL
1 stop11h 04m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
STL
- PTY
1 stop7h 02m
Delta
Wed 5/62:27 pm
PTY
- STL
1 stop9h 07m
Delta
Deal found 2/9![Delta logo]()
$415
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:03 pm
STL
- LIR
2 stops16h 21m
American Airlines
Fri 5/12:10 pm
LIR
- STL
1 stop17h 44m
American Airlines
Deal found 2/9![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:45 am
STL
- PTY
2 stops11h 46m
United Airlines
Sat 4/253:30 pm
PTY
- STL
1 stop17h 55m
United Airlines
Deal found 2/9![United Airlines logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:13 pm
STL
- SAP
2 stops16h 05m
Multiple Airlines
Tue 5/1212:13 pm
SAP
- STL
1 stop10h 06m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:25 pm
STL
- SJO
1 stop7h 35m
Southwest
Thu 5/281:10 pm
SJO
- STL
1 stop9h 45m
Southwest
Deal found 2/9![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:05 am
STL
- PTY
1 stop8h 33m
United Airlines
Tue 3/173:41 pm
PTY
- STL
1 stop17h 40m
United Airlines
Deal found 2/10![United Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:57 pm
STL
- LIR
1 stop17h 26m
American Airlines
Wed 3/2512:21 pm
LIR
- STL
2 stops19h 34m
American Airlines
Deal found 2/11![American Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:55 pm
STL
- SAP
1 stop19h 23m
Multiple Airlines
Sat 4/2512:13 pm
SAP
- STL
2 stops21h 17m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:11 am
STL
- SJO
1 stop11h 51m
Delta
Tue 3/37:00 am
SJO
- STL
1 stop7h 47m
Delta
Deal found 2/11![Delta logo]()
$447
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
STL
- PTY
1 stop10h 12m
United Airlines
Thu 4/910:00 am
PTY
- STL
1 stop12h 28m
United Airlines
Deal found 2/10![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:35 am
STL
- SJO
1 stop12h 05m
Southwest
Tue 3/311:55 pm
SJO
- STL
1 stop7h 55m
Southwest
Deal found 2/10![Southwest logo]()
$444
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:15 am
STL
- BZE
1 stop7h 15m
American Airlines
Tue 3/173:39 pm
BZE
- STL
2 stops15h 56m
American Airlines
Deal found 2/10![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
STL
- GUA
1 stop6h 46m
Delta
Sat 5/91:05 pm
GUA
- STL
1 stop9h 54m
Delta
Deal found 2/12![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
STL
- PTY
1 stop10h 12m
United Airlines
Mon 4/2710:00 am
PTY
- STL
1 stop12h 28m
United Airlines
Deal found 2/10![United Airlines logo]()
$425
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:10 am
STL
- SJO
1 stop10h 29m
United Airlines
Fri 2/272:00 pm
SJO
- STL
1 stop9h 59m
United Airlines
Deal found 2/10![United Airlines logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/294:51 pm
STL
- SAP
1 stop18h 13m
Multiple Airlines
Sun 4/51:52 pm
SAP
- STL
2 stops16h 59m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$493
Last-minute flights from St. Louis to Central AmericaDiscover last-minute flight deals from St. Louis to Central America. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Central America. Data last updated February 12, 2026 and is based on user searches.
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 am
STL
- LIR
1 stop8h 15m
LATAM Airlines
Mon 2/233:30 pm
LIR
- STL
1 stop17h 36m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/164:13 pm
STL
- LIR
2 stops19h 57m
American Airlines
Mon 2/233:29 pm
LIR
- STL
2 stops18h 04m
American Airlines
Deal found 2/9![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:12 am
STL
- LIR
1 stop9h 13m
American Airlines
Mon 3/23:29 pm
LIR
- STL
1 stop7h 53m
American Airlines
Deal found 2/11![American Airlines logo]()
$372
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/223:49 pm
STL
- GUA
1 stop19h 31m
Multiple Airlines
Wed 3/412:15 pm
GUA
- STL
1 stop10h 12m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- GUA
2 stops14h 58m
Multiple Airlines
Wed 3/412:15 pm
GUA
- STL
1 stop10h 12m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:49 pm
STL
- SJO
1 stop19h 51m
Multiple Airlines
Fri 2/271:31 pm
SJO
- STL
2 stops17h 20m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:14 am
STL
- BZE
1 stop7h 04m
American Airlines
Tue 3/101:50 pm
BZE
- STL
1 stop9h 08m
American Airlines
Deal found 2/8![American Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/53:49 pm
STL
- GUA
1 stop19h 31m
Multiple Airlines
Mon 3/911:15 am
GUA
- STL
1 stop11h 04m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- GUA
2 stops22h 11m
Multiple Airlines
Mon 3/911:15 am
GUA
- STL
1 stop11h 04m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:15 am
STL
- BZE
1 stop8h 35m
American Airlines
Tue 3/173:39 pm
BZE
- STL
1 stop7h 19m
American Airlines
Deal found 2/10![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:57 pm
STL
- LIR
2 stops19h 16m
American Airlines
Wed 3/2512:21 pm
LIR
- STL
1 stop10h 37m
American Airlines
Deal found 2/10![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:57 pm
STL
- LIR
1 stop17h 26m
American Airlines
Wed 3/2512:21 pm
LIR
- STL
2 stops19h 34m
American Airlines
Deal found 2/11![American Airlines logo]()
$357
One-way flights from St. Louis to Central AmericaSearch for one-way flight options from St. Louis to Central America. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from St. Louis to Central America. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
STL
- BZE
1 stop6h 15m
Delta
Deal found 2/8![Delta logo]()
$128
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:00 am
STL
- BZE
1 stop6h 15m
Delta
Deal found 2/12![Delta logo]()
$133
This Air Canada deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:05 pm
STL
- BZE
2 stops30h 00m
Air Canada
Deal found 2/8![Air Canada logo]()
$138
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
STL
- BZE
1 stop6h 14m
United Airlines
Deal found 2/10![United Airlines logo]()
$154
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:18 pm
STL
- BZE
2 stops16h 23m
American Airlines
Deal found 2/8![American Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:16 pm
STL
- SJO
2 stops23h 26m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$163
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:03 pm
STL
- BZE
2 stops16h 02m
American Airlines
Deal found 2/12![American Airlines logo]()
$167
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:18 pm
STL
- BZE
2 stops18h 00m
American Airlines
Deal found 2/8![American Airlines logo]()
$169
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
STL
- BZE
1 stop6h 16m
Delta
Deal found 2/12![Delta logo]()
$174
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
STL
- PTY
1 stop12h 38m
United Airlines
Deal found 2/9![United Airlines logo]()
$175
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:32 am
STL
- SJO
1 stop6h 43m
American Airlines
Deal found 2/8![American Airlines logo]()
$175
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:03 pm
STL
- BZE
2 stops19h 27m
American Airlines
Deal found 2/12![American Airlines logo]()
$180
Find flight deals from St. Louis to Central America
Keep the following information in mind while searching for St. Louis to Central America flight deals. Data was last updated February 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $341 (Kiwi.com) |
One-way from | $128 (Delta) |
Popular in | December |
Cheapest in | January |
Average price | $613 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from St. Louis to Central America that are best for you.
Fly from
St. Louis
Fly to
Central America
Route
Depart
Return
Price
St. LouisBelize City
STL - BZE
STLBZE
Lambert-St Louis
Tue 4/21
6:00 am-11:16 am
1 stop6h 16m
Belize City Philip S.W.Goldson
Tue 4/28
12:41 pm-11:34 pm
1 stop9h 53m
$341
St. LouisBelize City
STL - BZE
STLBZE
Lambert-St Louis
Tue 4/21
5:15 am-12:30 pm
1 stop8h 15m
Belize City Philip S.W.Goldson
Wed 4/29
1:25 pm-10:20 pm
1 stop7h 55m
$341
St. LouisLiberia
STL - LIR
STLLIR
Lambert-St Louis
Mon 5/4
5:24 am-1:10 pm
1 stop8h 46m
Liberia
Wed 5/13
12:30 pm-10:24 pm
1 stop8h 54m
$342
St. LouisBelize City
STL - BZE
STLBZE
Lambert-St Louis
Tue 3/3
5:14 am-1:50 pm
1 stop8h 36m
Belize City Philip S.W.Goldson
Tue 3/10
1:50 pm-8:55 am
2 stops18h 05m
$346
St. LouisBelize City
STL - BZE
STLBZE
Lambert-St Louis
Tue 4/21
5:46 am-2:30 pm
2 stops9h 44m
Belize City Philip S.W.Goldson
Tue 4/28
3:31 pm-1:22 pm
2 stops20h 51m
$346
St. LouisBelize City
STL - BZE
STLBZE
Lambert-St Louis
Tue 4/21
5:46 am-2:30 pm
2 stops9h 44m
Belize City Philip S.W.Goldson
Wed 4/29
1:52 pm-8:30 am
2 stops17h 38m
$346
St. LouisLiberia
STL - LIR
STLLIR
Lambert-St Louis
Sun 4/26
8:03 pm-11:24 am
2 stops16h 21m
Liberia
Fri 5/1
2:10 pm-8:54 am
1 stop17h 44m
$347
St. LouisLiberia
STL - LIR
STLLIR
Lambert-St Louis
Sat 3/21
6:57 pm-11:23 am
1 stop17h 26m
Liberia
Wed 3/25
12:21 pm-8:55 am
2 stops19h 34m
$357
St. LouisSan José
STL - SJO
STLSJO
Lambert-St Louis
Tue 4/28
10:25 am-7:00 pm
2 stops9h 35m
San José Juan Santamaria Intl
Fri 5/1
9:00 am-11:40 pm
1 stop13h 40m
$361
St. LouisSan Pedro Sula
STL - SAP
STLSAP
Lambert-St Louis
Wed 4/8
4:54 pm-10:04 am
1 stop18h 10m
San Pedro Sula Ramon Villeda
Wed 4/15
10:52 am-10:30 am
2 stops22h 38m
$366
Showing 1-10 of 60 results
Best time to book a flight from St. Louis to Central America
Have a flexible travel schedule? Discover the best time to fly to Central America from St. Louis with our price prediction graph.
STL-GUA
STL-BZE
STL-LIR
STL-SJO
STL-SAP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Central America
STL-0CA
STL-GUA
STL-BZE
STL-LIR
STL-SJO
What is the cheapest month to book a flight from St. Louis to Central America?
Currently, June is the cheapest month in which you can book a flight from St. Louis to Central America (average of $198). Flying from St. Louis to Central America in July is currently the most expensive (average of $372). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Central America
Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated February 12, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from St. Louis to Central America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for St. Louis to Central America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Central America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Central America by cabin class
Find flights from St. Louis to Central America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Central America flights
Browse other St. Louis and Central America flight options. Last updated on February 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Central America countries
Consider these flights traveling to countries located in Central America.
St. Louis to Central America flights
Consider these flights traveling from St. Louis to Central America.
Top 4 airlines flying from St. Louis to Central America
Discover the top 4 airlines that operate flights from St. Louis to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$209 | Average$518 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$287 | Average$575 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$319 | Average$550 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$376 | Average$599 | FlexibilityNo cancel fee | On-time63% |