How long is the flight from St. Louis to Central America?

A quick flight from St. Louis to Central America can take about 6h 50m. Delta provides one of the quickest options available for as low as $321. The distance from St. Louis to Central America is about 1967 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from St. Louis to Central America one-way?

One-way options have recently been found by users for as low as $129 on United Airlines. Other airlines that offer cheap prices include Delta from $131 and American Airlines from $159 one-way.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the most popular routes from St. Louis to Central America?

The most popular flight routes from St. Louis to Central America are Lambert-St Louis - San José Juan Santamaria Intl, Lambert-St Louis - Panama City Tocumen Intl and Lambert-St Louis - Belize City Philip S.W.Goldson.

What are the most popular airlines that fly from St. Louis to Central America?

When booking a flight from St. Louis to Central America, you may want to consider flying on American Airlines, United Airlines or Delta as they are the most popular for this route.

What is the cheapest time of day to fly from STL to CA?

When flying from St. Louis to Central America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from St. Louis to Central America?

If you book a flight to Central America from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

Can I find deals for flights from St. Louis to Central America that include hotel bookings?

Yes. In addition to deals on St. Louis to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Central America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Central America.

Can I find deals for business class flights from St. Louis to Central America?

Yes. Cheapflights offers flight deals from St. Louis to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$134+ Flights from St. Louis to Central America

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Cheap flight deals from St. Louis to Central America

Cheapest flights from St. Louis to Central America
Explore the most affordable flight options available from St. Louis to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Sat 12/275:45 pmSTL - LIR

1 stop17h 39mUnited Airlines

Wed 12/318:35 amLIR - STL

1 stop8h 11mUnited Airlines

Deal found 12/27

$404

Wed 12/314:53 pmSTL - LIR

2 stops19h 19mAmerican Airlines

Fri 1/22:37 pmLIR - STL

1 stop9h 18mAmerican Airlines

Deal found 12/27

$428

Sun 12/284:05 pmSTL - BZE

2 stops30h 00mAir Canada

Tue 1/1311:00 amBZE - STL

2 stops28h 29mAir Canada

Deal found 12/26

$457

Tue 12/305:00 amSTL - BZE

1 stop7h 31mAmerican Airlines

Mon 1/124:16 pmBZE - STL

1 stop16h 52mAmerican Airlines

Deal found 12/27

$465

Sun 12/285:40 amSTL - LIR

1 stop7h 57mAmerican Airlines

Fri 1/22:37 pmLIR - STL

1 stop17h 58mAmerican Airlines

Deal found 12/27

$471

Tue 12/308:05 amSTL - SJO

2 stops10h 11mUnited Airlines

Thu 1/12:20 pmSJO - STL

1 stop7h 35mUnited Airlines

Deal found 12/26

$476

Tue 12/306:00 amSTL - BZE

1 stop6h 14mUnited Airlines

Thu 1/13:00 pmBZE - STL

1 stop7h 43mUnited Airlines

Deal found 12/26

$482

Mon 12/298:01 pmSTL - LIR

1 stop17h 36mAmerican Airlines

Fri 1/22:37 pmLIR - STL

1 stop9h 18mAmerican Airlines

Deal found 12/25

$527

Sat 12/275:45 pmSTL - LIR

1 stop17h 39mUnited Airlines

Thu 1/18:35 amLIR - STL

1 stop8h 01mUnited Airlines

Deal found 12/26

$547

Wed 12/316:00 pmSTL - SJO

1 stop16h 32mAmerican Airlines

Sat 1/102:54 pmSJO - STL

1 stop20h 09mAmerican Airlines

Deal found 12/27

$563

Sat 12/276:44 pmSTL - LIR

2 stops17h 28mAmerican Airlines

Thu 1/11:21 pmLIR - STL

2 stops10h 34mAmerican Airlines

Deal found 12/26

$575

Tue 12/306:35 pmSTL - BZE

2 stops17h 48mAmerican Airlines

Thu 1/11:35 pmBZE - STL

2 stops19h 21mAmerican Airlines

Deal found 12/26

$587

Best flights from St. Louis to Central America
Discover carefully curated flight deals from St. Louis to Central America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Tue 2/35:42 pmSTL - GUA

1 stop17h 38mMultiple Airlines

Tue 2/1012:15 pmGUA - STL

1 stop10h 12mMultiple Airlines

Deal found 12/27

$250

Mon 2/26:00 amSTL - LIR

1 stop6h 50mDelta

Tue 2/102:45 pmLIR - STL

1 stop8h 40mDelta

Deal found 12/27

$321

Mon 2/25:59 pmSTL - LIR

2 stops18h 38mAmerican Airlines

Tue 2/103:13 pmLIR - STL

2 stops18h 27mAmerican Airlines

Deal found 12/27

$326

Wed 2/46:40 pmSTL - LIR

1 stop18h 15mUnited Airlines

Mon 2/98:35 amLIR - STL

1 stop13h 25mUnited Airlines

Deal found 12/27

$341

Wed 2/411:55 amSTL - SJO

1 stop7h 35mSouthwest

Wed 2/119:40 amSJO - STL

1 stop10h 55mSouthwest

Deal found 12/26

$349

Fri 1/96:44 pmSTL - LIR

2 stops17h 46mAmerican Airlines

Thu 1/153:13 pmLIR - STL

2 stops18h 11mAmerican Airlines

Deal found 12/27

$345

Sat 2/76:00 amSTL - SJO

1 stop16h 15mDelta

Fri 2/137:00 amSJO - STL

1 stop7h 47mDelta

Deal found 12/27

$348

Wed 2/410:10 amSTL - SJO

2 stops10h 29mUnited Airlines

Wed 2/118:45 amSJO - STL

2 stops14h 13mUnited Airlines

Deal found 12/26

$369

Sat 2/79:59 amSTL - SJO

1 stop12h 16mDelta

Thu 2/127:00 amSJO - STL

1 stop13h 41mDelta

Deal found 12/27

$348

Mon 2/26:00 amSTL - SJO

1 stop16h 30mAmerican Airlines

Mon 2/96:00 amSJO - STL

1 stop17h 59mAmerican Airlines

Deal found 12/26

$352

Tue 1/206:00 amSTL - BZE

1 stop6h 14mUnited Airlines

Mon 1/261:18 pmBZE - STL

1 stop8h 42mUnited Airlines

Deal found 12/25

$378

Sat 2/216:56 pmSTL - SJO

1 stop17h 49mAmerican Airlines

Mon 3/23:04 pmSJO - STL

1 stop17h 48mAmerican Airlines

Deal found 12/26

$359

Fri 2/136:00 amSTL - SJO

1 stop7h 00mDelta

Tue 2/177:00 amSJO - STL

1 stop7h 47mDelta

Deal found 12/27

$388

Tue 2/176:00 amSTL - PTY

1 stop10h 07mUnited Airlines

Wed 2/254:41 pmPTY - STL

1 stop17h 42mUnited Airlines

Deal found 12/26

$394

Mon 2/23:54 pmSTL - BZE

2 stops20h 28mAmerican Airlines

Fri 2/612:59 pmBZE - STL

2 stops11h 00mAmerican Airlines

Deal found 12/27

$359

Tue 3/106:00 amSTL - PTY

1 stop7h 45mUnited Airlines

Tue 3/1711:35 amPTY - STL

1 stop10h 41mUnited Airlines

Deal found 12/27

$394

Wed 4/296:00 amSTL - PTY

1 stop6h 55mDelta

Wed 5/62:20 pmPTY - STL

1 stop9h 13mDelta

Deal found 12/26

$394

Sat 1/2410:17 amSTL - BZE

1 stop25h 32mAmerican Airlines

Fri 1/3012:59 pmBZE - STL

1 stop10h 13mAmerican Airlines

Deal found 12/27

$362

Wed 2/410:20 amSTL - PTY

1 stop8h 18mUnited Airlines

Mon 2/94:41 pmPTY - STL

1 stop17h 41mUnited Airlines

Deal found 12/27

$394

Sat 2/146:56 pmSTL - BZE

1 stop16h 51mAmerican Airlines

Wed 2/184:40 pmBZE - STL

2 stops20h 06mAmerican Airlines

Deal found 12/27

$363

Sun 2/17:10 amSTL - LIR

1 stop6h 40mDelta

Sat 2/282:45 pmLIR - STL

1 stop8h 38mDelta

Deal found 12/26

$404

Tue 2/106:00 amSTL - PTY

1 stop10h 07mUnited Airlines

Tue 2/174:41 pmPTY - STL

1 stop17h 42mUnited Airlines

Deal found 12/27

$394

Wed 2/43:54 pmSTL - LIR

2 stops20h 18mAmerican Airlines

Mon 2/93:13 pmLIR - STL

2 stops18h 27mAmerican Airlines

Deal found 12/27

$365

Tue 3/246:00 amSTL - PTY

1 stop12h 38mUnited Airlines

Wed 4/17:55 amPTY - STL

1 stop14h 33mUnited Airlines

Deal found 12/25

$394

Sat 3/216:53 pmSTL - LIR

2 stops19h 26mAmerican Airlines

Wed 3/2512:21 pmLIR - STL

2 stops19h 14mAmerican Airlines

Deal found 12/26

$366

Sat 1/316:00 amSTL - GUA

1 stop6h 45mDelta

Sat 2/72:10 pmGUA - STL

1 stop9h 26mDelta

Deal found 12/26

$458

Tue 2/176:00 amSTL - PTY

1 stop10h 07mUnited Airlines

Tue 2/244:41 pmPTY - STL

1 stop17h 42mUnited Airlines

Deal found 12/28

$394

Tue 3/36:43 pmSTL - BZE

2 stops17h 24mAmerican Airlines

Tue 3/101:50 pmBZE - STL

2 stops18h 12mAmerican Airlines

Deal found 12/25

$367

Tue 3/106:00 amSTL - PTY

1 stop7h 45mUnited Airlines

Mon 3/163:41 pmPTY - STL

1 stop17h 40mUnited Airlines

Deal found 12/26

$394

Sat 5/97:03 pmSTL - BZE

2 stops16h 32mAmerican Airlines

Fri 5/151:30 pmBZE - STL

1 stop7h 05mAmerican Airlines

Deal found 12/27

$367

Last-minute flights from St. Louis to Central America
Discover last-minute flight deals from St. Louis to Central America. Data last updated December 28, 2025 and is based on user searches.

Sat 12/275:45 pmSTL - LIR

1 stop17h 39mUnited Airlines

Wed 12/318:35 amLIR - STL

1 stop8h 11mUnited Airlines

Deal found 12/27

$404

Fri 1/94:05 pmSTL - LIR

1 stop22h 40mAir Canada

Fri 1/163:45 pmLIR - STL

1 stop23h 44mAir Canada

Deal found 12/28

$336

Fri 1/95:59 pmSTL - LIR

2 stops18h 38mAmerican Airlines

Fri 1/163:13 pmLIR - STL

2 stops19h 50mAmerican Airlines

Deal found 12/28

$345

Tue 1/206:00 amSTL - BZE

1 stop6h 14mUnited Airlines

Mon 1/261:18 pmBZE - STL

1 stop8h 42mUnited Airlines

Deal found 12/25

$378

Tue 1/203:54 pmSTL - BZE

2 stops20h 28mAmerican Airlines

Mon 1/262:27 pmBZE - STL

2 stops19h 13mAmerican Airlines

Deal found 12/25

$383

Fri 1/233:54 pmSTL - BZE

2 stops20h 28mAmerican Airlines

Sat 1/312:45 pmBZE - STL

2 stops19h 35mAmerican Airlines

Deal found 12/27

$407

Sat 1/245:04 pmSTL - BZE

2 stops18h 45mAmerican Airlines

Fri 1/304:16 pmBZE - STL

2 stops18h 04mAmerican Airlines

Deal found 12/27

$359

Mon 1/265:42 pmSTL - SJO

1 stop17h 55mMultiple Airlines

Mon 2/161:31 pmSJO - STL

2 stops32h 56mMultiple Airlines

Deal found 12/26

$411

Tue 1/276:00 amSTL - SJO

1 stop16h 30mAmerican Airlines

Sun 2/1511:25 amSJO - STL

1 stop23h 01mAmerican Airlines

Deal found 12/26

$408

Thu 1/296:00 amSTL - PTY

1 stop7h 45mUnited Airlines

Sun 2/18:55 amPTY - STL

1 stop14h 05mUnited Airlines

Deal found 12/26

$411

Fri 1/309:33 amSTL - SJO

2 stops10h 11mAmerican Airlines

Sat 2/77:09 amSJO - STL

1 stop13h 04mAmerican Airlines

Deal found 12/27

$389

Sat 1/3110:00 amSTL - SJO

1 stop11h 02mAmerican Airlines

Wed 2/1112:43 amSJO - STL

1 stop16h 22mAmerican Airlines

Deal found 12/26

$388

One-way flights from St. Louis to Central America
Search for one-way flight options from St. Louis to Central America. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Wed 2/183:49 pmSTL - SJO

1 stop19h 51mMultiple Airlines

Deal found 12/27

$134

Mon 2/166:00 amSTL - SJO

1 stop14h 39mUnited Airlines

Deal found 12/27

$143

Tue 2/173:49 pmSTL - SJO

2 stops20h 33mMultiple Airlines

Deal found 12/27

$152

Sat 2/149:41 amSTL - SJO

2 stops26h 41mMultiple Airlines

Deal found 12/27

$153

Tue 3/104:51 pmSTL - GUA

1 stop18h 29mMultiple Airlines

Deal found 12/27

$156

Mon 3/167:00 pmSTL - PTY

2 stops18h 45mUnited Airlines

Deal found 12/26

$164

Sun 2/152:00 pmSTL - SJO

2 stops20h 25mAmerican Airlines

Deal found 12/27

$165

Mon 2/166:50 pmSTL - SJO

2 stops19h 14mAmerican Airlines

Deal found 12/27

$171

Mon 3/166:59 pmSTL - PTY

1 stop18h 04mDelta

Deal found 12/26

$177

Fri 1/168:32 pmSTL - SJO

1 stop17h 10mFrontier

Deal found 12/26

$179

Thu 3/121:36 pmSTL - PTY

2 stops22h 46mAmerican Airlines

Deal found 12/27

$234

Sun 3/153:33 pmSTL - PTY

2 stops20h 49mAmerican Airlines

Deal found 12/26

$240

Find flight deals from St. Louis to Central America

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$250 (Trip.com)
One-way from	$134 (Kiwi.com)
Popular in	December
Cheapest in	January
Average price	$1,187

Provider with most accurate pricing for Lambert-St Louis-San Salvador El Salvador Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-San Salvador El Salvador Intl flights.

Search Deals

From Lambert-St Louis to Central America

Search Deals

One-way flight from Lambert-St Louis to Central America

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($175 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 10% potential price decrease ($57 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGuatemala City

STL - GUA

STLGUA

Lambert-St Louis

Tue 2/3

5:42 pm-11:20 am

1 stop17h 38m

Guatemala City La Aurora

Tue 2/10

12:15 pm-10:27 pm

1 stop10h 12m

$250

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 2/2

6:00 am-12:50 pm

1 stop6h 50m

Liberia

Tue 2/10

2:45 pm-11:25 pm

1 stop8h 40m

$321

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 2/2

5:59 pm-12:37 pm

2 stops18h 38m

Liberia

Tue 2/10

3:13 pm-9:40 am

2 stops18h 27m

$326

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Wed 2/4

6:40 pm-12:55 pm

1 stop18h 15m

Liberia

Mon 2/9

8:35 am-10:00 pm

1 stop13h 25m

$341

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Fri 1/9

6:44 pm-12:30 pm

2 stops17h 46m

Liberia

Thu 1/15

3:13 pm-9:24 am

2 stops18h 11m

$345

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sat 2/7

6:00 am-10:15 pm

1 stop16h 15m

San José Juan Santamaria Intl

Fri 2/13

7:00 am-2:47 pm

1 stop7h 47m

$348

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sat 2/7

9:59 am-10:15 pm

1 stop12h 16m

San José Juan Santamaria Intl

Thu 2/12

7:00 am-8:41 pm

1 stop13h 41m

$348

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Wed 2/4

11:55 am-7:30 pm

1 stop7h 35m

San José Juan Santamaria Intl

Wed 2/11

9:40 am-8:35 pm

1 stop10h 55m

$349

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Mon 2/2

6:00 am-10:30 pm

1 stop16h 30m

San José Juan Santamaria Intl

Mon 2/9

6:00 am-11:59 pm

1 stop17h 59m

$352

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sat 2/21

6:56 pm-12:45 pm

1 stop17h 49m

San José Juan Santamaria Intl

Mon 3/2

3:04 pm-8:52 am

1 stop17h 48m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 50 results

...

Best time to book a flight from St. Louis to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Central America

What is the cheapest month to book a flight from St. Louis to Central America?

Currently, June is the cheapest month in which you can book a flight from St. Louis to Central America (average of $201). Flying from St. Louis to Central America in March is currently the most expensive (average of $347). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Central America

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from St. Louis to Central America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,256 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,019 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,113 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,073 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly from for flights from St. Louis to Central America?
If you book a flight to Central America from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.
How long is the flight from St. Louis to Central America?
A quick flight from St. Louis to Central America can take about 6h 50m. Delta provides one of the quickest options available for as low as $321. The distance from St. Louis to Central America is about 1967 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from St. Louis to Central America one-way?
One-way options have recently been found by users for as low as $129 on United Airlines. Other airlines that offer cheap prices include Delta from $131 and American Airlines from $159 one-way.
What are the most popular routes from St. Louis to Central America?
The most popular flight routes from St. Louis to Central America are Lambert-St Louis - San José Juan Santamaria Intl, Lambert-St Louis - Panama City Tocumen Intl and Lambert-St Louis - Belize City Philip S.W.Goldson.
Can I find deals for flights from St. Louis to Central America that include hotel bookings?
Yes. In addition to deals on St. Louis to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Central America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Central America.
Can I find deals for business class flights from St. Louis to Central America?
Yes. Cheapflights offers flight deals from St. Louis to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Central America?
Currently, June is the cheapest month in which you can book a flight from St. Louis to Central America (average of $201). Flying from St. Louis to Central America in March is currently the most expensive (average of $347). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

El Salvador car rentals

Costa Rica car rentals

Honduras car rentals

Guatemala car rentals

Panama car rentals

Nicaragua car rentals

Belize car rentals

Guatemala City La Aurora Airport car rentals

San Salvador El Salvador Intl Airport car rentals

Panama City Tocumen Intl Airport car rentals

Liberia Airport car rentals

San Pedro Sula Ramon Villeda Airport car rentals

Managua Augusto C Sandino Airport car rentals

Belize City Philip S.W.Goldson Airport car rentals

Coxen Hole Roatan Airport car rentals

Flores Santa Elena Airport car rentals

Tegucigalpa Toncontin Airport car rentals

La Ceiba Goloson Intl Airport car rentals

Top 4 airlines flying from St. Louis to Central America

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$257	Average$540	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$287	Average$587	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$319	Average$599	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$383	Average$606	FlexibilityNo cancel fee	On-time63%

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$134+ Cheap flights from St. Louis (STL) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from St. Louis to Central America

Cheapest flights from St. Louis to Central AmericaExplore the most affordable flight options available from St. Louis to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from St. Louis to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from St. Louis to Central America

Keep the following information in mind while searching for St. Louis to Central America flight deals. Data was last updated December 28, 2025.

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Reviews of airlines servicing Central America

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from St. Louis to Central America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Alternative routes for St. Louis to Central America

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Top 4 airlines flying from St. Louis to Central America

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Cheapest flights from St. Louis to Central America
Explore the most affordable flight options available from St. Louis to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.