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Central America

$225+ Cheap flights from Panama City, FL (ECP) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SJO
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Cheap flight deals from Panama City to Central America

Keep the following information in mind while searching for Panama City to Central America flight deals. Data was last updated octubre 29, 2025.

Round-trip from

$496
(United Airlines)

One-way from

$225
(United Airlines)
From Panama City NW Florida Beaches to Central America
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One-way flight from Panama City NW Florida Beaches to Central America
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Find flight deals from Panama City to Central America

Cheapest flights from Panama City to Central America
Explore the most affordable flight options available from Panama City to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/56:30 amECP - SJO
1 stop14h 09mUnited Airlines
mié. 11/1212:35 pmSJO - ECP
1 stop9h 14mUnited Airlines
Deal found 10/27$494
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/136:30 amECP - PTY
1 stop12h 08mUnited Airlines
sáb. 12/204:41 pmPTY - ECP
1 stop17h 36mUnited Airlines
Deal found 10/29$496
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/58:21 amECP - SJO
2 stops12h 56mAmerican Airlines
mié. 11/126:00 amSJO - ECP
2 stops17h 15mAmerican Airlines
Deal found 10/27$498
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/105:00 pmECP - SJO
1 stop18h 25mUnited Airlines
jue. 11/202:20 pmSJO - ECP
1 stop7h 29mUnited Airlines
Deal found 10/27$503
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/276:30 amECP - SJO
1 stop6h 45mUnited Airlines
jue. 12/42:20 pmSJO - ECP
1 stop7h 29mUnited Airlines
Deal found 10/28$512
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:30 amECP - SJO
1 stop14h 41mAmerican Airlines
vie. 12/196:20 amSJO - ECP
2 stops17h 33mAmerican Airlines
Deal found 10/28$516
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/117:15 amECP - SJO
2 stops13h 15mSouthwest
jue. 11/139:00 amSJO - ECP
2 stops12h 05mSouthwest
Deal found 10/28$518
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/12:40 pmECP - SJO
2 stops22h 32mAmerican Airlines
mié. 11/52:59 pmSJO - ECP
2 stops19h 34mAmerican Airlines
Deal found 10/29$528
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:30 amECP - SJO
1 stop14h 09mUnited Airlines
lun. 12/88:45 amSJO - ECP
1 stop13h 04mUnited Airlines
Deal found 10/29$530
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:30 amECP - SJO
1 stop14h 41mAmerican Airlines
lun. 12/86:20 amSJO - ECP
2 stops16h 50mAmerican Airlines
Deal found 10/29$534
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/125:00 pmECP - PTY
1 stop20h 45mUnited Airlines
vie. 12/194:41 pmPTY - ECP
1 stop17h 36mUnited Airlines
Deal found 10/28$574
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:30 amECP - LIR
1 stop7h 49mAmerican Airlines
jue. 12/181:27 pmLIR - ECP
1 stop10h 26mAmerican Airlines
Deal found 10/27$598

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Panama City to Central America that are best for you.

Fly from

Panama City

Fly to

Central America

Route

Depart

Return

Price

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

sáb. 12/13

6:30 am-7:38 pm

1 stop12h 08m

Panama City Tocumen Intl

sáb. 12/20

4:41 pm-9:17 am

1 stop17h 36m

$496

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

lun. 3/16

2:58 pm-11:00 am

2 stops21h 02m

San José Juan Santamaria Intl

lun. 3/23

12:01 am-2:06 pm

1 stop13h 05m

$498

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

lun. 11/10

5:55 pm-2:10 pm

2 stops20h 15m

San José Juan Santamaria Intl

jue. 11/20

1:35 pm-11:49 pm

1 stop10h 14m

$498

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

lun. 11/10

5:00 pm-11:25 am

1 stop18h 25m

San José Juan Santamaria Intl

jue. 11/20

2:20 pm-9:49 pm

1 stop7h 29m

$503

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

vie. 12/12

12:55 pm-9:11 pm

1 stop8h 16m

San José Juan Santamaria Intl

jue. 12/18

12:34 am-12:10 pm

1 stop11h 36m

$512

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

jue. 11/27

6:30 am-1:15 pm

1 stop6h 45m

San José Juan Santamaria Intl

jue. 12/4

2:20 pm-9:49 pm

1 stop7h 29m

$512

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

jue. 1/8

3:27 pm-11:43 pm

1 stop8h 16m

San José Juan Santamaria Intl

jue. 1/15

4:01 pm-1:04 pm

2 stops21h 03m

$516

Panama CityLiberia

ECP - LIR

ECPLIR

Panama City NW Florida Beaches

lun. 3/16

6:40 am-12:10 pm

1 stop6h 30m

Liberia

mar. 3/24

1:20 pm-10:00 pm

1 stop7h 40m

$537

Panama CityLiberia

ECP - LIR

ECPLIR

Panama City NW Florida Beaches

lun. 3/16

5:01 pm-11:15 am

2 stops19h 14m

Liberia

mar. 3/24

2:55 pm-12:16 pm

2 stops20h 21m

$541

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

vie. 12/12

5:00 pm-2:45 pm

1 stop20h 45m

Panama City Tocumen Intl

vie. 12/19

4:41 pm-9:17 am

1 stop17h 36m

$574

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 29 results
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Best time to book a flight from Panama City to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Central America

What is the cheapest month to book a flight from Panama City, Florida to Central America?

Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to Central America (average of $226). Flying from Panama City, Florida to Central America in February is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to CA?

Find hourly flight availability from Panama City to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 29, 2025.

It’s optimal to fly from Panama City, Florida to Central America in the evening. By choosing this option you can save up to 28% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated octubre 29, 2025.
Read through reviews of airlines operating flights from Panama City to Central America, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Central America?

    For a flight from Panama City to Central America, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from Panama City, Florida to Central America?

    There are many flights that can get you from Panama City, Florida to Central America in 12h 08m. Fly via United Airlines or American Airlines to get the fastest option. There are 1527 mi between Panama City, Florida and Central America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Panama City, Florida to Central America one-way?

    One-way options have recently been found by users for as low as $225 on American Airlines. Other airlines that offer cheap prices include United Airlines from $225 and Southwest from $226 one-way.

  • What are the most popular routes from Panama City, Florida to Central America?

    Most travelers choose Panama City NW Florida Beaches - San José Juan Santamaria Intl, Panama City NW Florida Beaches - Liberia or Panama City NW Florida Beaches - Panama City Tocumen Intl when deciding on the best route from Panama City, Florida to Central America.

  • Can I find deals for flights from Panama City to Central America that include hotel bookings?

    Yes. In addition to deals on Panama City to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Central America.

  • Can I find deals for business class flights from Panama City to Central America?

    Yes. Cheapflights offers flight deals from Panama City to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Central America?

    Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to Central America (average of $226). Flying from Panama City, Florida to Central America in February is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Central America

Discover the top 2 airlines that operate flights from Panama City to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$395Average$627FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$404Average$603FlexibilityNo cancel feeOn-time69%

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