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Central America

$295+ Cheap flights from Panama City, FL (ECP) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SJO
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Panama City to Central America

Cheapest flights from Panama City to Central America
Explore the most affordable flight options available from Panama City to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:30 am
ECP
-
PTY
1 stop12h 07m
United Airlines
Wed 4/227:55 am
PTY
-
ECP
1 stop14h 04m
United Airlines
Deal found 2/2$477
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:30 am
ECP
-
PTY
1 stop9h 37m
United Airlines
Wed 3/253:41 pm
PTY
-
ECP
1 stop30h 16m
United Airlines
Deal found 2/2$485
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 am
ECP
-
PTY
1 stop7h 15m
United Airlines
Thu 3/127:55 am
PTY
-
ECP
1 stop14h 02m
United Airlines
Deal found 2/2$497
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/53:00 pm
ECP
-
PTY
2 stops23h 15m
American Airlines
Thu 3/191:40 pm
PTY
-
ECP
2 stops20h 26m
American Airlines
Deal found 2/2$501
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:30 am
ECP
-
PTY
1 stop12h 08m
United Airlines
Thu 3/193:41 pm
PTY
-
ECP
1 stop24h 30m
United Airlines
Deal found 2/2$525
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 am
ECP
-
SJO
1 stop6h 51m
United Airlines
Tue 6/212:30 am
SJO
-
ECP
1 stop14h 56m
United Airlines
Deal found 2/2$526
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
ECP
-
SJO
2 stops13h 14m
American Airlines
Wed 6/36:12 am
SJO
-
ECP
2 stops16h 29m
American Airlines
Deal found 2/2$531
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:33 pm
ECP
-
SJO
1 stop10h 03m
American Airlines
Thu 5/712:35 pm
SJO
-
ECP
1 stop10h 11m
American Airlines
Deal found 2/1$544
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:20 pm
ECP
-
SJO
1 stop8h 15m
American Airlines
Sat 7/1811:59 pm
SJO
-
ECP
2 stops17h 24m
American Airlines
Deal found 1/31$579
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/113:00 pm
ECP
-
PTY
2 stops23h 20m
American Airlines
Wed 3/253:10 pm
PTY
-
ECP
2 stops23h 58m
American Airlines
Deal found 2/2$591
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:34 pm
ECP
-
SJO
2 stops17h 50m
American Airlines
Thu 3/192:59 pm
SJO
-
ECP
2 stops18h 07m
American Airlines
Deal found 2/2$597
This Gurufare deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 pm
ECP
-
SJO
1 stop6h 34m
Multiple Airlines
Tue 6/21:25 pm
SJO
-
ECP
1 stop7h 32m
Multiple Airlines
Deal found 2/2$626

Find flight deals from Panama City to Central America

Keep the following information in mind while searching for Panama City to Central America flight deals. Data was last updated February 3, 2026.

Round-trip from

$477
(United Airlines)

One-way from

$295
(American Airlines)
From Panama City NW Florida Beaches to Central America
Search Deals
One-way flight from Panama City NW Florida Beaches to Central America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Panama City to Central America that are best for you.

Fly from

Panama City

Fly to

Central America

Route

Depart

Return

Price

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Sat 4/18

6:30 am-2:14 pm

1 stop7h 44m

Panama City Tocumen Intl

Wed 4/22

7:55 am-9:59 pm

1 stop14h 04m

$477

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Wed 3/18

6:30 am-6:38 pm

1 stop12h 08m

Panama City Tocumen Intl

Wed 3/25

3:41 pm-9:57 pm

1 stop30h 16m

$485

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Tue 3/10

6:30 am-1:45 pm

1 stop7h 15m

Panama City Tocumen Intl

Thu 3/12

7:55 am-9:57 pm

1 stop14h 02m

$497

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 3/5

3:00 pm-3:15 pm

2 stops23h 15m

Panama City Tocumen Intl

Thu 3/19

1:40 pm-10:06 am

2 stops20h 26m

$501

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 3/5

6:30 am-7:38 pm

1 stop12h 08m

Panama City Tocumen Intl

Thu 3/19

3:41 pm-4:11 pm

1 stop24h 30m

$525

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Fri 5/1

12:33 pm-9:36 pm

1 stop10h 03m

San José Juan Santamaria Intl

Thu 5/7

12:35 pm-11:46 pm

1 stop10h 11m

$544

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Wed 3/11

3:00 pm-2:20 pm

2 stops23h 20m

Panama City Tocumen Intl

Wed 3/25

3:10 pm-3:08 pm

2 stops23h 58m

$591

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Thu 3/5

4:34 pm-10:24 am

2 stops17h 50m

San José Juan Santamaria Intl

Thu 3/19

2:59 pm-10:06 am

2 stops18h 07m

$597

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Tue 3/24

3:00 pm-2:20 pm

2 stops23h 20m

Panama City Tocumen Intl

Fri 3/27

3:10 pm-3:08 pm

2 stops23h 58m

$631

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 3/2

6:30 am-8:39 pm

1 stop14h 09m

San José Juan Santamaria Intl

Mon 3/9

5:30 am-9:57 pm

1 stop15h 27m

$643

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 22 results
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Best time to book a flight from Panama City to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Central America

What is the cheapest month to book a flight from Panama City, Florida to Central America?

Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Central America (average of $230). Flying from Panama City, Florida to Central America in October is currently the most expensive (average of $433). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated February 3, 2026.
Read through reviews of airlines operating flights from Panama City to Central America, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,138 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,138 reviews
Delta
7.9
Good
8,138 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,236 reviews
Delta
7.9
Good
8,138 reviews

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Central America?

    For a flight from Panama City to Central America, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from Panama City, Florida to Central America?

    There are many flights that can get you from Panama City, Florida to Central America in 7h 44m. Fly via United Airlines or American Airlines to get the fastest option. There are 1527 mi between Panama City, Florida and Central America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City, Florida to Central America?

    Most travelers choose Panama City NW Florida Beaches - San José Juan Santamaria Intl, Panama City NW Florida Beaches - Panama City Tocumen Intl or Panama City NW Florida Beaches - Liberia when deciding on the best route from Panama City, Florida to Central America.

  • Can I find deals for flights from Panama City to Central America that include hotel bookings?

    Yes. In addition to deals on Panama City to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Central America.

  • Can I find deals for business class flights from Panama City to Central America?

    Yes. Cheapflights offers flight deals from Panama City to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Central America?

    Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Central America (average of $230). Flying from Panama City, Florida to Central America in October is currently the most expensive (average of $433). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Central America

Discover the top 2 airlines that operate flights from Panama City to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$395Average$599FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$397Average$606FlexibilityNo cancel feeOn-time69%

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