HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Central America

$249+ Cheap flights from Panama City, FL (ECP) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SJO
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Central America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Central America

Cheapest flights from Panama City to Central America
Explore the most affordable flight options available from Panama City to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:09 pmECP - PTY
2 stops22h 45mAmerican Airlines
Fri 1/94:50 pmPTY - ECP
2 stops21h 20mAmerican Airlines
Deal found 12/14$600
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:45 pmECP - SJO
1 stop27h 54mUnited Airlines
Fri 12/2612:35 pmSJO - ECP
1 stop9h 19mUnited Airlines
Deal found 12/13$632
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:52 amECP - SJO
1 stop8h 24mUnited Airlines
Fri 1/26:30 amSJO - ECP
1 stop7h 50mUnited Airlines
Deal found 12/14$697
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:45 pmECP - SJO
1 stop29h 47mUnited Airlines
Sat 12/276:30 amSJO - ECP
1 stop15h 24mUnited Airlines
Deal found 12/14$744
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:09 pmECP - SJO
2 stops18h 23mAmerican Airlines
Fri 12/267:00 amSJO - ECP
2 stops16h 53mAmerican Airlines
Deal found 12/13$758
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:15 amECP - PTY
1 stop12h 23mUnited Airlines
Fri 1/98:55 amPTY - ECP
1 stop8h 17mUnited Airlines
Deal found 12/14$824
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:28 pmECP - SJO
2 stops19h 04mAmerican Airlines
Fri 12/2612:34 amSJO - ECP
1 stop20h 47mAmerican Airlines
Deal found 12/15$907
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/272:55 pmECP - LIR
1 stop27h 42mUnited Airlines
Fri 1/28:35 amLIR - ECP
1 stop7h 35mUnited Airlines
Deal found 12/13$1,187
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/274:09 pmECP - LIR
2 stops20h 17mAmerican Airlines
Fri 1/21:21 pmLIR - ECP
2 stops21h 20mAmerican Airlines
Deal found 12/13$1,404

Find flight deals from Panama City to Central America

Keep the following information in mind while searching for Panama City to Central America flight deals. Data was last updated December 15, 2025.

Round-trip from

$436
(United Airlines)

One-way from

$249
(Delta)
From Panama City NW Florida Beaches to Central America
Search Deals
One-way flight from Panama City NW Florida Beaches to Central America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Panama City to Central America that are best for you.

Fly from

Panama City

Fly to

Central America

Route

Depart

Return

Price

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Sun 2/8

1:10 pm-10:15 pm

1 stop9h 05m

San José Juan Santamaria Intl

Tue 2/10

7:00 am-2:56 pm

1 stop7h 56m

$440

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Wed 1/28

3:27 pm-1:27 pm

2 stops21h 00m

Panama City Tocumen Intl

Wed 2/4

2:27 pm-1:04 pm

2 stops23h 37m

$460

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Mon 2/2

6:30 am-7:38 pm

1 stop12h 08m

Panama City Tocumen Intl

Fri 2/6

4:41 pm-12:02 pm

1 stop20h 21m

$464

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Tue 1/6

6:03 pm-1:54 pm

2 stops19h 51m

San José Juan Santamaria Intl

Wed 3/4

3:55 pm-12:45 pm

2 stops20h 50m

$498

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 1/8

6:30 am-2:45 pm

1 stop7h 15m

Panama City Tocumen Intl

Mon 1/19

4:41 pm-12:02 pm

1 stop20h 21m

$504

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Wed 5/6

6:55 am-9:55 pm

1 stop16h 00m

San José Juan Santamaria Intl

Sat 5/9

2:35 pm-9:24 am

1 stop17h 49m

$512

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Wed 1/7

6:03 pm-1:54 pm

2 stops19h 51m

San José Juan Santamaria Intl

Wed 1/21

1:43 pm-11:33 am

2 stops21h 50m

$516

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 1/8

3:27 pm-1:27 pm

2 stops21h 00m

Panama City Tocumen Intl

Mon 1/19

4:50 pm-1:04 pm

2 stops21h 14m

$520

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Thu 1/8

3:27 pm-11:43 pm

1 stop8h 16m

San José Juan Santamaria Intl

Thu 1/15

2:54 pm-9:19 pm

1 stop30h 25m

$521

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Wed 1/28

6:00 am-1:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 2/4

3:20 pm-10:40 pm

1 stop8h 20m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 17 results
1
2

Best time to book a flight from Panama City to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Central America

What is the cheapest month to book a flight from Panama City, Florida to Central America?

Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Central America (average of $230). Flying from Panama City, Florida to Central America in October is currently the most expensive (average of $433). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to CA?

Find hourly flight availability from Panama City to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

It’s optimal to fly from Panama City, Florida to Central America in the evening. By choosing this option you can save up to 28% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated December 15, 2025.
Read through reviews of airlines operating flights from Panama City to Central America, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Central America?

    For a flight from Panama City to Central America, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from Panama City, Florida to Central America?

    There are many flights that can get you from Panama City, Florida to Central America in 9h 05m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. There are 1410 mi between Panama City, Florida and Central America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City, Florida to Central America?

    Most travelers choose Panama City NW Florida Beaches - San José Juan Santamaria Intl, Panama City NW Florida Beaches - Panama City Tocumen Intl or Panama City NW Florida Beaches - Liberia when deciding on the best route from Panama City, Florida to Central America.

  • Can I find deals for flights from Panama City to Central America that include hotel bookings?

    Yes. In addition to deals on Panama City to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Central America.

  • Can I find deals for business class flights from Panama City to Central America?

    Yes. Cheapflights offers flight deals from Panama City to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Central America?

    Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Central America (average of $230). Flying from Panama City, Florida to Central America in October is currently the most expensive (average of $433). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Central America

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Luis Munoz Marin Intl flights
Miami to LaGuardia flights
Fort Lauderdale to John F Kennedy Intl flights
Orlando to John F Kennedy Intl flights
Miami to John F Kennedy Intl flights
Fort Lauderdale to Newark flights
Fort Lauderdale to LaGuardia flights
Miami to Newark flights
Tampa to John F Kennedy Intl flights
West Palm Beach to Newark flights
Orlando to Newark flights
Orlando to Las Vegas flights
Tampa to LaGuardia flights
Miami to Madrid flights
Miami to Jose Maria Cordova Intl flights
Miami to Denver flights
Fort Lauderdale to Las Vegas flights
Orlando to LaGuardia flights
Orlando to Denver flights
Tampa to Newark flights
Orlando to Dallas/Fort Worth flights
Fort Lauderdale to Jose Maria Cordova Intl flights
West Palm Beach to John F Kennedy Intl flights
Fort Lauderdale to Dallas/Fort Worth flights
Tampa to Luis Munoz Marin Intl flights
Fort Lauderdale to Denver flights
Miami to Mexico City flights
Orlando to Los Angeles flights
Tampa to Denver flights
Miami to Cancún flights
Orlando to Punta Cana flights
Fort Lauderdale to Luis Munoz Marin Intl flights
Miami to Las Vegas flights
Tampa to Las Vegas flights
Miami to Luis Munoz Marin Intl flights
Miami to Lima flights
Miami to Los Angeles flights
Orlando to Cancún flights
Miami to Ministro Pistarini flights
Jacksonville to John F Kennedy Intl flights
Miami to Dallas/Fort Worth flights
Fort Lauderdale to Los Angeles flights
Tampa to Dallas/Fort Worth flights
Miami to Leonardo da Vinci/Fiumicino flights
Miami to Punta Cana flights
Jacksonville to LaGuardia flights
Fort Lauderdale to Cancún flights
Orlando to Heathrow flights
Fort Lauderdale to Atlanta flights
Miami to Heathrow flights

Top 2 airlines flying from Panama City to Central America

Discover the top 2 airlines that operate flights from Panama City to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$395Average$599FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$397Average$590FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.