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Central America

$128+ Cheap flights from Myrtle Beach (MYR) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SJO
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Central America

Keep the following information in mind while searching for Myrtle Beach to Central America flight deals. Data was last updated October 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$283
(Cheapflightsfares)

One-way from

$128
(Trip.com)
Provider with most accurate pricing for Myrtle Beach Intl-San Salvador El Salvador Intl flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Salvador El Salvador Intl flights.
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From Myrtle Beach Intl to Central America
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One-way flight from Myrtle Beach Intl to Central America
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Find flight deals from Myrtle Beach to Central America

Cheapest flights from Myrtle Beach to Central America
Explore the most affordable flight options available from Myrtle Beach to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:15 amMYR - SJO
1 stop6h 24mSpirit Airlines
Mon 11/171:30 pmSJO - MYR
1 stop7h 56mSpirit Airlines
Deal found 10/18$283
This CheapOair deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:15 amMYR - SJO
1 stop6h 24mSpirit Airlines
Sat 11/221:20 pmSJO - MYR
1 stop9h 34mSpirit Airlines
Deal found 10/18$284
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:46 amMYR - SJO
1 stop27h 39mSpirit Airlines
Wed 12/101:31 pmSJO - MYR
1 stop27h 17mSpirit Airlines
Deal found 10/19$312
This Cheapflightsfares deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:15 amMYR - SJO
1 stop6h 24mSpirit Airlines
Sun 11/161:30 pmSJO - MYR
1 stop7h 56mSpirit Airlines
Deal found 10/17$321
This Priceline deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:54 amMYR - MGA
1 stop5h 49mSpirit Airlines
Fri 12/123:53 pmMGA - MYR
2 stops20h 27mSpirit Airlines
Deal found 10/19$333
This Mytrip deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:15 amMYR - SJO
1 stop10h 05mMultiple Airlines
Wed 12/1012:39 pmSJO - MYR
3 stops27h 07mMultiple Airlines
Deal found 10/19$358
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:15 pmMYR - GUA
2 stops24h 32mSpirit Airlines
Mon 12/221:29 pmGUA - MYR
1 stop27h 39mSpirit Airlines
Deal found 10/19$405
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:54 amMYR - GUA
2 stops28h 53mSpirit Airlines
Mon 12/221:29 pmGUA - MYR
1 stop27h 39mSpirit Airlines
Deal found 10/20$435
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:03 pmMYR - PTY
2 stops21h 44mAmerican Airlines
Thu 3/121:50 pmPTY - MYR
2 stops19h 02mAmerican Airlines
Deal found 10/19$440
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:41 pmMYR - PTY
2 stops18h 06mAmerican Airlines
Tue 12/94:43 pmPTY - MYR
2 stops18h 56mAmerican Airlines
Deal found 10/17$460
This Mytrip deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/139:54 amMYR - GUA
2 stops28h 53mMultiple Airlines
Mon 12/221:59 pmGUA - MYR
2 stops27h 09mMultiple Airlines
Deal found 10/19$468
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:41 pmMYR - PTY
2 stops18h 06mAmerican Airlines
Thu 12/42:50 pmPTY - MYR
2 stops19h 14mAmerican Airlines
Deal found 10/20$480

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Central America that are best for you.

Fly from

Myrtle Beach

Fly to

Central America

Route

Depart

Return

Price

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 11/10

6:15 am-11:39 am

1 stop6h 24m

San José Juan Santamaria Intl

Mon 11/17

1:30 pm-10:26 pm

1 stop7h 56m

$283

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 11/8

6:15 am-11:39 am

1 stop6h 24m

San José Juan Santamaria Intl

Sat 11/22

1:20 pm-11:54 pm

1 stop9h 34m

$284

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 1/26

11:46 am-12:21 am

1 stop13h 35m

San José Juan Santamaria Intl

Sun 2/1

1:16 am-10:41 am

1 stop8h 25m

$300

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 11/10

6:15 am-11:39 am

1 stop6h 24m

San José Juan Santamaria Intl

Sun 11/16

1:30 pm-10:26 pm

1 stop7h 56m

$321

Myrtle BeachManagua

MYR - MGA

MYRMGA

Myrtle Beach Intl

Fri 12/5

9:54 am-2:43 pm

1 stop5h 49m

Managua Augusto C Sandino

Fri 12/12

3:53 pm-1:20 pm

2 stops20h 27m

$333

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Sat 12/13

2:15 pm-1:47 pm

2 stops24h 32m

Guatemala City La Aurora

Mon 12/22

1:29 pm-6:08 pm

1 stop27h 39m

$405

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Sun 12/14

9:54 am-1:47 pm

2 stops28h 53m

Guatemala City La Aurora

Mon 12/22

1:29 pm-6:08 pm

1 stop27h 39m

$435

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

8:41 pm-12:10 pm

2 stops16h 29m

Panama City Tocumen Intl

Thu 3/26

1:50 pm-12:11 pm

2 stops21h 21m

$440

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 12/15

4:03 pm-1:47 pm

2 stops21h 44m

Panama City Tocumen Intl

Thu 3/12

1:50 pm-9:52 am

2 stops19h 02m

$440

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 12/2

7:41 pm-1:47 pm

2 stops18h 06m

Panama City Tocumen Intl

Tue 12/9

4:43 pm-11:39 am

2 stops18h 56m

$460

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/18

Showing 1-10 of 30 results
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Best time to book a flight from Myrtle Beach to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Central America

What is the cheapest month to book a flight from Myrtle Beach to Central America?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Central America (average of $159). Flying from Myrtle Beach to Central America in October is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to CA?

Find hourly flight availability from Myrtle Beach to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

It’s optimal to fly from Myrtle Beach to Central America in the afternoon. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Myrtle Beach to Central America?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Central America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Central America flight should consider departing on Wednesday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated October 20, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Central America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,976 reviews
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,026 reviews
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,104 reviews
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Central America?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Central America. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Central America?

    There are many flights that can get you from Myrtle Beach to Central America in 6h 24m. Fly via Spirit Airlines, American Airlines, or Delta to get the fastest option. There are 1670 mi between Myrtle Beach and Central America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to Central America?

    When deciding which route to take from Myrtle Beach to Central America consider Myrtle Beach Intl - San José Juan Santamaria Intl, Myrtle Beach Intl - Panama City Tocumen Intl or Myrtle Beach Intl - Belize City Philip S.W.Goldson as they are the most popular.

  • Can I find deals for flights from Myrtle Beach to Central America that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Central America.

  • Can I find deals for business class flights from Myrtle Beach to Central America?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Central America?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Central America (average of $159). Flying from Myrtle Beach to Central America in October is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Central America

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Top 3 airlines flying from Myrtle Beach to Central America

Discover the top 3 airlines that operate flights from Myrtle Beach to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$267Average$386FlexibilityNo cancel feeOn-time65%
DeltaCheapest$378Average$644FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$437Average$670FlexibilityNo cancel feeOn-time71%

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