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Central America

$219+ Cheap flights from Myrtle Beach (MYR) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SJO
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Central America

Cheapest flights from Myrtle Beach to Central America
Explore the most affordable flight options available from Myrtle Beach to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This KAYAK deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:54 amMYR - SJO
1 stop27h 31mSpirit Airlines
Sun 12/281:31 pmSJO - MYR
1 stop27h 37mSpirit Airlines
Deal found 12/2$460
This KAYAK deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:27 pmMYR - SJO
1 stop16h 15mSpirit Airlines
Sat 1/171:30 pmSJO - MYR
2 stops21h 42mSpirit Airlines
Deal found 12/3$514
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - SJO
1 stop27h 31mMultiple Airlines
Wed 1/73:10 pmSJO - MYR
2 stops22h 32mMultiple Airlines
Deal found 12/3$515
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:03 pmMYR - PTY
2 stops21h 44mAmerican Airlines
Tue 12/162:50 pmPTY - MYR
2 stops19h 14mAmerican Airlines
Deal found 12/3$580
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:34 pmMYR - PTY
2 stops23h 19mAmerican Airlines
Tue 12/304:55 pmPTY - MYR
2 stops18h 43mAmerican Airlines
Deal found 12/3$639
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - SJO
1 stop27h 31mSpirit Airlines
Wed 1/71:31 pmSJO - MYR
1 stop28h 49mSpirit Airlines
Deal found 12/3$639
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amMYR - SJO
2 stops15h 14mAmerican Airlines
Sun 12/281:31 pmSJO - MYR
1 stop18h 49mAmerican Airlines
Deal found 12/2$699
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amMYR - PTY
1 stop8h 21mDelta
Tue 12/163:46 pmPTY - MYR
1 stop7h 57mDelta
Deal found 12/3$788
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:54 amMYR - PTY
3 stops24h 36mMultiple Airlines
Mon 12/152:55 amPTY - MYR
3 stops42h 57mMultiple Airlines
Deal found 12/3$802
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:54 amMYR - PTY
3 stops22h 56mMultiple Airlines
Mon 12/292:55 amPTY - MYR
2 stops15h 13mMultiple Airlines
Deal found 12/3$816
This Mytrip deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:27 pmMYR - GUA
2 stops16h 57mSpirit Airlines
Fri 12/53:00 pmGUA - MYR
2 stops25h 48mSpirit Airlines
Deal found 12/4$829
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amMYR - PTY
1 stop14h 00mDelta
Tue 12/308:00 amPTY - MYR
1 stop14h 50mDelta
Deal found 12/3$868

Find flight deals from Myrtle Beach to Central America

Keep the following information in mind while searching for Myrtle Beach to Central America flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$330
(Kiwi.com)

One-way from

$219
(American Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-San Salvador El Salvador Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Salvador El Salvador Intl flights.
Search Deals
From Myrtle Beach Intl to Central America
Search Deals
One-way flight from Myrtle Beach Intl to Central America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Central America that are best for you.

Fly from

Myrtle Beach

Fly to

Central America

Route

Depart

Return

Price

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sun 2/1

10:00 am-11:37 am

2 stops26h 37m

San José Juan Santamaria Intl

Mon 2/9

1:30 pm-12:12 pm

2 stops21h 42m

$404

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 2/14

12:39 pm-11:40 am

1 stop24h 01m

San José Juan Santamaria Intl

Sun 2/22

1:31 pm-8:15 am

1 stop17h 44m

$406

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Tue 2/3

1:07 pm-11:37 am

1 stop23h 30m

San José Juan Santamaria Intl

Tue 2/10

12:33 pm-9:21 pm

2 stops31h 48m

$409

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 1/26

8:15 pm-11:37 am

2 stops40h 22m

San José Juan Santamaria Intl

Mon 2/2

1:30 pm-9:03 am

2 stops18h 33m

$421

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 5/4

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 5/6

2:20 pm-11:38 pm

1 stop8h 18m

$436

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 5/4

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 5/5

2:20 pm-11:38 pm

1 stop8h 18m

$436

Myrtle BeachManagua

MYR - MGA

MYRMGA

Myrtle Beach Intl

Mon 3/9

8:07 pm-2:00 pm

2 stops19h 53m

Managua Augusto C Sandino

Mon 3/16

12:21 pm-10:39 am

2 stops20h 18m

$437

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 4/28

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Mon 5/4

2:20 pm-10:09 am

1 stop18h 49m

$443

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 4/29

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Mon 5/4

2:20 pm-1:36 pm

1 stop22h 16m

$443

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 5/3

6:45 pm-12:55 pm

1 stop19h 10m

Panama City Tocumen Intl

Thu 5/7

2:20 pm-11:38 pm

1 stop8h 18m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 39 results
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Best time to book a flight from Myrtle Beach to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Central America

What is the cheapest month to book a flight from Myrtle Beach to Central America?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Central America (average of $159). Flying from Myrtle Beach to Central America in October is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to CA?

Find hourly flight availability from Myrtle Beach to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s optimal to fly from Myrtle Beach to Central America in the afternoon. By choosing this option you can save up to 41% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Myrtle Beach to Central America?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Central America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Central America flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated December 4, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Central America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,161 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Central America?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Central America. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Central America?

    There are many flights that can get you from Myrtle Beach to Central America in 7h 55m. Fly via Spirit Airlines, Delta, or American Airlines to get the fastest option. There are 1700 mi between Myrtle Beach and Central America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to Central America?

    When deciding which route to take from Myrtle Beach to Central America consider Myrtle Beach Intl - Panama City Tocumen Intl, Myrtle Beach Intl - San José Juan Santamaria Intl or Myrtle Beach Intl - Belize City Philip S.W.Goldson as they are the most popular.

  • Can I find deals for flights from Myrtle Beach to Central America that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Central America.

  • Can I find deals for business class flights from Myrtle Beach to Central America?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Central America?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Central America (average of $159). Flying from Myrtle Beach to Central America in October is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Myrtle Beach to Central America

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Top 3 airlines flying from Myrtle Beach to Central America

Discover the top 3 airlines that operate flights from Myrtle Beach to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$278Average$381FlexibilityNo cancel feeOn-time65%
DeltaCheapest$378Average$639FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$437Average$665FlexibilityNo cancel feeOn-time71%

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