Central America

$126+ Cheap flights from Myrtle Beach (MYR) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SJO
Feb 22 — Mar 11
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Central America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Myrtle Beach to Central America

Cheapest flights from Myrtle Beach to Central America
Explore the most affordable flight options available from Myrtle Beach to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 23, 2026.

This CheapOair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:51 pm
MYR
-
SJO
1 stop17h 31m
Spirit Airlines
Mon 4/2712:31 pm
SJO
-
MYR
1 stop19h 11m
Spirit Airlines
Deal found 1/22$323
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:09 am
MYR
-
SJO
2 stops27h 31m
Spirit Airlines
Sat 3/71:31 pm
SJO
-
MYR
1 stop16h 42m
Spirit Airlines
Deal found 1/21$341
This CheapOair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:09 am
MYR
-
GUA
1 stop28h 15m
Spirit Airlines
Mon 3/1612:33 pm
GUA
-
MYR
1 stop27h 06m
Spirit Airlines
Deal found 1/22$367
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/58:15 pm
MYR
-
SJO
2 stops16h 22m
Spirit Airlines
Mon 2/91:30 pm
SJO
-
MYR
1 stop28h 40m
Spirit Airlines
Deal found 1/21$379
This CheapOair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:54 pm
MYR
-
SJO
2 stops15h 28m
Spirit Airlines
Sun 3/1512:24 pm
SJO
-
MYR
1 stop27h 15m
Spirit Airlines
Deal found 1/22$382
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/88:15 pm
MYR
-
SJO
2 stops40h 22m
Spirit Airlines
Sat 2/1412:35 pm
SJO
-
MYR
2 stops18h 38m
Spirit Airlines
Deal found 1/21$394
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:54 pm
MYR
-
GUA
2 stops38h 26m
Multiple Airlines
Mon 3/1612:33 pm
GUA
-
MYR
1 stop27h 06m
Multiple Airlines
Deal found 1/22$412
This CheapOair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/268:15 pm
MYR
-
GUA
2 stops16h 05m
Spirit Airlines
Sat 2/712:15 pm
GUA
-
MYR
1 stop22h 57m
Spirit Airlines
Deal found 1/22$463
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:19 pm
MYR
-
PTY
2 stops20h 21m
American Airlines
Thu 3/261:40 pm
PTY
-
MYR
2 stops17h 52m
American Airlines
Deal found 1/22$481
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2610:00 am
MYR
-
GUA
1 stop21h 50m
Multiple Airlines
Sat 2/712:15 pm
GUA
-
MYR
1 stop22h 57m
Multiple Airlines
Deal found 1/22$509
This Priceline deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:26 pm
MYR
-
GUA
1 stop5h 27m
Spirit Airlines
Fri 8/712:58 am
GUA
-
MYR
1 stop6h 55m
Spirit Airlines
Deal found 1/21$529
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:23 am
MYR
-
BZE
2 stops10h 27m
American Airlines
Sun 8/232:50 pm
BZE
-
MYR
2 stops17h 32m
American Airlines
Deal found 1/22$535

Find flight deals from Myrtle Beach to Central America

Keep the following information in mind while searching for Myrtle Beach to Central America flight deals. Data was last updated January 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Ovago
2 stars

Round-trip from

$323
(CheapOair)

One-way from

$126
(CheapOair)
Provider with most accurate pricing for Myrtle Beach Intl-San Salvador El Salvador Intl flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Salvador El Salvador Intl flights.
From Myrtle Beach Intl to Central America
One-way flight from Myrtle Beach Intl to Central America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Central America that are best for you.

Fly from

Myrtle Beach

Fly to

Central America

Route

Depart

Return

Price

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 4/20

7:51 pm-11:22 am

1 stop17h 31m

San José Juan Santamaria Intl

Mon 4/27

12:31 pm-9:42 am

1 stop19h 11m

$323

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Fri 2/27

9:09 am-11:40 am

2 stops27h 31m

San José Juan Santamaria Intl

Sat 3/7

1:31 pm-7:13 am

1 stop16h 42m

$341

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Mon 3/9

9:09 am-11:24 am

1 stop28h 15m

Guatemala City La Aurora

Mon 3/16

12:33 pm-5:39 pm

1 stop27h 06m

$367

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Thu 2/5

8:15 pm-11:37 am

2 stops16h 22m

San José Juan Santamaria Intl

Mon 2/9

1:30 pm-7:10 pm

1 stop28h 40m

$379

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sun 3/8

9:54 pm-11:22 am

2 stops15h 28m

San José Juan Santamaria Intl

Sun 3/15

12:24 pm-5:39 pm

1 stop27h 15m

$382

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Mon 3/9

9:54 pm-10:20 am

2 stops38h 26m

Guatemala City La Aurora

Mon 3/16

12:33 pm-5:39 pm

1 stop27h 06m

$412

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 7/22

6:25 pm-12:10 pm

2 stops18h 45m

Panama City Tocumen Intl

Tue 7/28

1:10 pm-11:48 am

2 stops21h 38m

$481

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:22 pm-2:20 pm

2 stops20h 58m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-12:14 pm

2 stops21h 34m

$481

Myrtle BeachBelize City

MYR - BZE

MYRBZE

Myrtle Beach Intl

Sat 3/7

6:26 pm-10:41 am

2 stops17h 15m

Belize City Philip S.W.Goldson

Sun 3/15

3:39 pm-2:27 pm

2 stops20h 48m

$573

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 2/10

5:44 pm-1:27 pm

2 stops19h 43m

Panama City Tocumen Intl

Tue 3/3

2:40 pm-11:39 am

2 stops20h 59m

$591

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/22

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Myrtle Beach to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Central America

What is the cheapest month to book a flight from Myrtle Beach to Central America?

Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Central America (average of $141). Flying from Myrtle Beach to Central America in October is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated January 23, 2026.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Central America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Myrtle Beach to Central America?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Central America. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Central America?

    There are many flights that can get you from Myrtle Beach to Central America in 8h 07m. Fly via Spirit Airlines, American Airlines, or Delta to get the fastest option. There are 1700 mi between Myrtle Beach and Central America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to Central America?

  • Can I find deals for flights from Myrtle Beach to Central America that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Central America.

  • Can I find deals for business class flights from Myrtle Beach to Central America?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Central America?

    Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Central America (average of $141). Flying from Myrtle Beach to Central America in October is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Central America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Myrtle Beach to Central America

Discover the top 3 airlines that operate flights from Myrtle Beach to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$267Average$405FlexibilityNo cancel feeOn-time65%
DeltaCheapest$378Average$627FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$464Average$684FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.