$240+ Cheap flights from Knoxville (TYS) to Cancún (CUN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CUN
Nov 2 — Nov 91
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Cancún with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Cancún
Cheapest
Best
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One-way
Cheapest flights from Knoxville to CancúnExplore the most affordable flight options available from Knoxville to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2026.
Explore the most affordable flight options available from Knoxville to Cancún. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2026.
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:15 am -
1 stop6h 40m
Wed 11/188:20 am -
2 stops11h 30m
Deal found 9/29![Southwest logo]()
$519
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:05 am -
2 stops12h 40m
Wed 11/1112:35 pm -
1 stop8h 15m
Deal found 10/2![Southwest logo]()
$553
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:45 am -
1 stop7h 10m
Tue 11/38:39 am -
1 stop9h 15m
Deal found 9/29![United Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
2 stops10h 05m
Tue 11/33:25 pm -
1 stop7h 23m
Deal found 9/29![American Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 am -
1 stop7h 14m
Mon 11/212:28 pm -
1 stop9h 29m
Deal found 9/28![United Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:00 pm -
1 stop6h 01m
Fri 11/611:48 am -
1 stop12h 11m
Deal found 9/28![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:50 am -
1 stop9h 15m
Sun 12/2011:04 am -
1 stop6h 54m
Deal found 10/2![American Airlines logo]()
$605
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:00 am -
1 stop9h 55m
Wed 12/2311:20 am -
2 stops11h 15m
Deal found 10/2![Southwest logo]()
$610
Best flights from Knoxville to CancúnDiscover carefully curated flight deals from Knoxville to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 3, 2026.
Discover carefully curated flight deals from Knoxville to Cancún that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 3, 2026.
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:15 am -
1 stop6h 40m
Wed 11/188:20 am -
2 stops11h 30m
Deal found 9/29![Southwest logo]()
$519
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop15h 01m
Fri 11/611:48 am -
1 stop8h 32m
Deal found 10/2![American Airlines logo]()
$600
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:05 am -
2 stops12h 40m
Wed 11/1112:35 pm -
1 stop8h 15m
Deal found 10/2![Southwest logo]()
$553
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:20 am -
1 stop7h 40m
Fri 10/231:00 pm -
1 stop7h 35m
Deal found 9/29![Southwest logo]()
$629
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:10 am -
2 stops8h 55m
Sat 11/212:30 pm -
1 stop7h 10m
Deal found 9/30![Southwest logo]()
$630
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:05 am -
2 stops12h 40m
Thu 11/1912:35 pm -
1 stop8h 15m
Deal found 9/28![Southwest logo]()
$709
Last-minute flights from Knoxville to CancúnDiscover last-minute flight deals from Knoxville to Cancún. Data last updated October 3, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Cancún. Data last updated October 3, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:20 am -
1 stop7h 40m
Fri 10/231:00 pm -
1 stop7h 35m
Deal found 9/29![Southwest logo]()
$629
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 am -
1 stop7h 14m
Mon 11/212:28 pm -
1 stop9h 29m
Deal found 9/28![United Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:45 am -
1 stop7h 10m
Tue 11/38:39 am -
1 stop9h 15m
Deal found 9/29![United Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
2 stops10h 05m
Tue 11/33:25 pm -
1 stop7h 23m
Deal found 9/29![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:00 pm -
1 stop6h 01m
Fri 11/611:48 am -
1 stop12h 11m
Deal found 9/28![American Airlines logo]()
$600
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:05 am -
2 stops12h 40m
Wed 11/1112:35 pm -
1 stop8h 15m
Deal found 10/2![Southwest logo]()
$553
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:10 am -
2 stops8h 55m
Wed 11/188:20 am -
2 stops11h 30m
Deal found 9/29![Southwest logo]()
$519
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:10 am -
2 stops8h 55m
Sat 11/212:30 pm -
1 stop7h 10m
Deal found 9/30![Southwest logo]()
$630
One-way flights from Knoxville to CancúnSearch for one-way flight options from Knoxville to Cancún. Find affordable one-way fares based on user searches. Data last updated October 3, 2026.
Search for one-way flight options from Knoxville to Cancún. Find affordable one-way fares based on user searches. Data last updated October 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/249:45 am -
3 stops47h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:26 am -
2 stops25h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:32 pm -
2 stops37h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:04 am -
2 stops23h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:56 am -
2 stops25h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$311
This Aeromexico deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2412:00 pm -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Aeromexico logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:08 pm -
2 stops37h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:20 am -
2 stops28h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:30 am -
2 stops50h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Multiple Airlines logo]()
$386
Find flight deals from Knoxville to Cancún
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Cancún (CUN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $481 (Southwest) |
One-way from | $240 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $616 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Cancún that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
Use the filters below to find and compare flights from Knoxville to Cancún that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Tue 12/22
9:26 am-10:30 am
2 stops25h 04m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$262
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Sun 11/22
11:04 am-10:34 am
2 stops23h 30m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$269
Quickest round-trip
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Wed 12/23
7:00 am-2:55 pm
1 stop7h 55m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$330
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Sun 12/20
9:08 pm-10:30 am
2 stops37h 22m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$349
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Wed 12/23
8:52 pm-10:30 am
3 stops37h 38m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$393
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Thu 12/24
1:50 pm-12:45 am
3 stops34h 55m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$398
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Tue 10/6
12:06 pm-7:55 pm
1 stop8h 49m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$401
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Mon 12/21
12:21 pm-10:27 am
1 stop22h 06m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$432
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Mon 10/5
6:06 pm-11:32 am
2 stops18h 26m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$463
KnoxvilleCancún
TYS Knoxville McGhee Tyson - CUN Cancun
TYSCUN
Knoxville McGhee Tyson
Sat 11/14
8:15 am-2:55 pm
1 stop6h 40m
Cancun
Wed 11/18
8:20 am-7:50 pm
2 stops11h 30m
$519
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Cancún
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Cancún in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Cancún flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Cancún flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Cancún flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Cancún flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Cancún flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Cancún
Have a flexible travel schedule? Discover the best time to fly to Cancún from Knoxville with our price prediction graph.
TYS-CUN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Cancún
How far ahead should I book a flight from Knoxville to Cancún?
Booking 28 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Cancún. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Knoxville to Cancún?
Currently, April is the cheapest month in which you can book a flight from Knoxville to Cancún (average of $531). Flying from Knoxville to Cancún in December is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Cancún?
Airfare is below average for this route at the moment.
Knoxville to Cancún flights typically cost between $531 and $674 in January.The cheapest round-trip price found within the last 5 days was $481 on Southwest (Jan 17-Jan 27).
Reviews of airlines servicing Cancún
Get insights into the airlines that provide service to Cancún. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cancún. Reviews last updated October 3, 2026.
See what other customers who have flown with Southwest,Delta, andAeromexico from Knoxville to Cancún have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Cancún. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cancún?
Book flights to Cancún if you plan to visit one of these locationsPuerto Aventuras
Punta Sam
Holbox
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Knoxville to Cancún
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Other flights to Cancún
Explore flights to Cancún departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 3, 2026.
Complete your trip
Complete your trip to Cancún by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Knoxville to Cancún, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Cancún flights
Browse other Knoxville and Cancún flight options. Last updated on October 3, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Knoxville to Cancún
Discover the top 5 airlines that operate flights from Knoxville to Cancún. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$473 | Average$705 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$485 | Average$623 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$511 | Average$593 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$526 | Average$618 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$531 | Average$624 | FlexibilityNo cancel fee | On-time71% |