How long is the flight from Knoxville to Cusco?

There are many flights that can get you from Knoxville to Cusco in 18h. Fly via GOL to get the fastest option. Knoxville and Cusco are separated by a distance of 3497 mi.

In terms of precipitation, rainfall in Cusco ranges from 0.0 - 5.5 inches per month. January is typically the wettest month, when rainfall can reach 5.5 in. May is typically the driest time to visit Cusco when rainfall is around 0.0 in.

If weather is an important factor for your trip to Cusco, use this chart to help with planning. For those seeking warmer temperatures, October is the ideal time of year to visit, when temperatures reach an average of 55.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

What is the cheapest time of day to fly from TYS to CUZ?

When flying from Knoxville to Cusco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Knoxville-Cusco flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Knoxville-Cusco flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Knoxville-Cusco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Knoxville-Cusco flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Knoxville to Cuzco that include hotel bookings?

Yes. In addition to deals on Knoxville to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Cuzco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cuzco.

Can I find deals for business class flights from Knoxville to Cuzco?

Yes. Cheapflights offers flight deals from Knoxville to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$1,167+ Cheap Flights from Knoxville to Cusco

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Cheap flight deals from Knoxville to Cuzco

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Best flights from Knoxville to Cuzco
Discover carefully curated flight deals from Knoxville to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.

Fri 1/226:30 am -

3 stops33h 40m

Fri 1/297:55 pm -

2 stops23h 56m

Deal found 10/19

$1,167

Fri 1/224:20 pm -

3 stops18h 00m

Fri 1/299:30 pm -

3 stops16h 11m

Deal found 10/19

$1,188

Find flight deals from Knoxville to Cuzco

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$1,159 (KAYAK)

Provider with most accurate pricing for Knoxville McGhee Tyson-Cusco Velazco Astete flight deals.

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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cusco Velazco Astete flights.

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From Knoxville McGhee Tyson to Cusco Velazco Astete

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Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCusco

TYS Knoxville McGhee Tyson - CUZ Cusco Velazco Astete

TYSCUZ

Knoxville McGhee Tyson

Fri 1/22

6:30 am-4:10 pm

3 stops33h 40m

Cusco Velazco Astete

Fri 1/29

7:55 pm-7:51 pm

2 stops23h 56m

$1,167

Quickest round-trip

KnoxvilleCusco

TYS Knoxville McGhee Tyson - CUZ Cusco Velazco Astete

TYSCUZ

Knoxville McGhee Tyson

Fri 1/22

4:20 pm-10:20 am

3 stops18h 00m

Cusco Velazco Astete

Fri 1/29

9:30 pm-1:41 pm

3 stops16h 11m

$1,188

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/19

Sorted by cheapest first

Most accurate provider: When it comes to deals on Knoxville-Cusco flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Knoxville-Cusco flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Knoxville-Cusco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Knoxville-Cusco flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Knoxville with our price prediction graph.

TYS-CUZ

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Knoxville to Cusco?
There are many flights that can get you from Knoxville to Cusco in 18h. Fly via GOL to get the fastest option. Knoxville and Cusco are separated by a distance of 3497 mi.
Can I find deals for flights from Knoxville to Cuzco that include hotel bookings?
Yes. In addition to deals on Knoxville to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Cuzco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cuzco.
Can I find deals for business class flights from Knoxville to Cuzco?
Yes. Cheapflights offers flight deals from Knoxville to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Cuzco with Cheapflights

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Cheap flight deals from Knoxville to Cuzco

Best flights from Knoxville to Cuzco
Discover carefully curated flight deals from Knoxville to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.

Discover carefully curated flight deals from Knoxville to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.

Find flight deals from Knoxville to Cuzco

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Use the filters below to find and compare flights from Knoxville to Cusco that are best for you.

Best time to book a flight from Knoxville to Cuzco

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Related info for your journey

How long is the flight from Knoxville to Cusco?

Can I find deals for flights from Knoxville to Cuzco that include hotel bookings?

How can I find direct flights from Knoxville to Cuzco?

Can I find deals for business class flights from Knoxville to Cuzco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Cuzco

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Complete your trip

Complete your trip to Cuzco by adding a car rental and/or hotel reservation to your travel itinerary.

Other flights to Cuzco

Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.

Search flights from Knoxville to Cuzco by cabin class

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Knoxville and Cuzco flights

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$1,167+ Cheap flights from Knoxville (TYS) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Cuzco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Cuzco

Best flights from Knoxville to CuzcoDiscover carefully curated flight deals from Knoxville to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.

Discover carefully curated flight deals from Knoxville to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.

Find flight deals from Knoxville to Cuzco

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Cusco that are best for you.

Best time to book a flight from Knoxville to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Knoxville with our price prediction graph.

Related info for your journey

How long is the flight from Knoxville to Cusco?

Can I find deals for flights from Knoxville to Cuzco that include hotel bookings?

How can I find direct flights from Knoxville to Cuzco?

Can I find deals for business class flights from Knoxville to Cuzco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Cuzco by adding a car rental and/or hotel reservation to your travel itinerary.

Other flights to Cuzco

Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.

Search flights from Knoxville to Cuzco by cabin class

Find flights from Knoxville to Cuzco, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Knoxville and Cuzco flights

Browse other Knoxville and Cuzco flight options. Last updated on October 20, 2026.

Other flights from Knoxville

Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

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Best flights from Knoxville to Cuzco
Discover carefully curated flight deals from Knoxville to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.