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$412+ Cheap flights from Florence, SC to Buffalo (FLO - BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — BUF
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Florence to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$412
(American Airlines)
From Florence to Buffalo
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Find flight deals from Florence to Buffalo

Cheapest flights from Florence to Buffalo
Explore the most affordable flight options available from Florence to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:14 amFLO - BUF
2 stops10h 52mAmerican Airlines
Sun 11/212:35 pmBUF - FLO
2 stops11h 28mAmerican Airlines
Deal found 7/28$412

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Florence to Buffalo that are best for you.

Fly from

Florence

Fly to

Buffalo

Route

Depart

Return

Price

FlorenceBuffalo

FLO - BUF

FLOBUF

Florence

Fri 10/31

6:14 am-5:06 pm

2 stops10h 52m

Buffalo

Sun 11/2

12:35 pm-12:03 am

2 stops11h 28m

$412

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Florence to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Buffalo

What is the cheapest month to book a flight from Florence, South Carolina to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to Buffalo (average of $256). Flying from Florence, South Carolina to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with American Airlines from Florence to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Florence to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Florence to Buffalo that include hotel bookings?

    Yes. In addition to deals on Florence to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Buffalo.

  • Can I find deals for business class flights from Florence to Buffalo?

    Yes. Cheapflights offers flight deals from Florence to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to Buffalo (average of $256). Flying from Florence, South Carolina to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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