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$448+ Cheap flights from Knoxville (TYS) to Brazil

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GRU
Apr 18 — Apr 251
Sat 4/18
Sat 4/25
1 adult, Economy
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Cheap flight deals from Knoxville to Brazil

Cheapest flights from Knoxville to Brazil
Explore the most affordable flight options available from Knoxville to Brazil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:30 am
TYS
-
GRU
1 stop19h 30m
Multiple Airlines
Sun 9/271:20 am
GRU
-
TYS
2 stops21h 15m
Multiple Airlines
Deal found 3/17$871
This KAYAK deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:05 am
TYS
-
GRU
2 stops16h 05m
Copa Airlines
Mon 4/202:00 am
GRU
-
TYS
2 stops21h 34m
Copa Airlines
Deal found 3/15$1,244
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:53 pm
TYS
-
GRU
1 stop18h 07m
American Airlines
Wed 6/2411:15 pm
GRU
-
TYS
1 stop20h 49m
American Airlines
Deal found 3/18$1,263
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:45 am
TYS
-
GRU
2 stops26h 55m
United Airlines
Wed 6/2410:20 pm
GRU
-
TYS
2 stops17h 07m
United Airlines
Deal found 3/18$1,267
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:27 am
TYS
-
GRU
1 stop21h 13m
Multiple Airlines
Mon 7/131:00 am
GRU
-
TYS
2 stops15h 30m
Multiple Airlines
Deal found 3/18$1,290
This Orbitz deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:30 pm
TYS
-
GRU
2 stops36h 50m
LATAM Airlines
Mon 7/133:40 am
GRU
-
TYS
2 stops21h 06m
LATAM Airlines
Deal found 3/18$1,305
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:01 pm
TYS
-
GRU
1 stop14h 39m
United Airlines
Tue 7/1410:20 pm
GRU
-
TYS
1 stop15h 59m
United Airlines
Deal found 3/18$1,309
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:25 pm
TYS
-
GRU
1 stop18h 05m
United Airlines
Sat 5/309:30 pm
GRU
-
TYS
1 stop17h 57m
United Airlines
Deal found 3/18$1,318
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:48 pm
TYS
-
CWB
2 stops27h 22m
United Airlines
Mon 9/213:05 pm
CWB
-
TYS
2 stops26h 54m
United Airlines
Deal found 3/15$1,328
This Ovago deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:03 pm
TYS
-
GRU
1 stop16h 37m
LATAM Airlines
Tue 4/2110:50 pm
GRU
-
TYS
1 stop21h 11m
LATAM Airlines
Deal found 3/15$1,331

Find flight deals from Knoxville to Brazil

Keep the following information in mind while searching for Knoxville to Brazil flight deals. Data was last updated March 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,244
(KAYAK)

One-way from

$448
(Kiwi.com)
Provider with most accurate pricing for Knoxville McGhee Tyson-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sao Paulo (SAO) flights.
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From Knoxville McGhee Tyson to Brazil
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One-way flight from Knoxville McGhee Tyson to Brazil
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Brazil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
Use the filters below to find and compare flights from Knoxville to Brazil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 4/14

7:05 am-12:10 am

2 stops16h 05m

Sao Paulo Guarulhos Intl

Mon 4/20

2:00 am-10:34 pm

2 stops21h 34m

$1,244

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/17

3:30 pm-5:20 am

2 stops36h 50m

Sao Paulo Guarulhos Intl

Mon 7/13

3:40 am-11:46 pm

2 stops21h 06m

$1,305
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/17

6:01 pm-9:40 am

1 stop14h 39m

Sao Paulo Guarulhos Intl

Tue 7/14

10:20 pm-2:27 pm

2 stops17h 07m

$1,313

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

11:40 am-6:30 am

1 stop17h 50m

Sao Paulo Guarulhos Intl

Sat 5/30

9:30 pm-10:42 am

1 stop14h 12m

$1,318

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

1:20 pm-9:00 am

1 stop18h 40m

Sao Paulo Guarulhos Intl

Sat 5/30

10:00 pm-1:02 pm

1 stop16h 02m

$1,368

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 5/28

3:25 pm-6:30 am

1 stop14h 05m

Sao Paulo Guarulhos Intl

Mon 6/1

9:30 pm-2:27 pm

1 stop17h 57m

$1,403
Cheapest one-way

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/17

11:27 am-8:40 am

3 stops44h 13m

$448
Quickest one-way

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 4/23

3:58 pm-8:20 am

2 stops15h 22m

$718

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 4/23

1:52 pm-9:45 am

1 stop18h 53m

$743

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 3/27

12:21 pm-8:05 am

2 stops18h 44m

$956

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 11 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Brazil

Have a flexible travel schedule? Discover the best time to fly to Brazil from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Brazil
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Brazil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Brazil?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Brazil. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Brazil?

    Airlines like Copa Airlines, LATAM Airlines, and United Airlines fly from Knoxville to Brazil in about 14h 39m. The time it takes to get you to your destination can typically vary by up to 22h 11m. The distance between Knoxville and Brazil is about 4768 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Knoxville to Brazil that include hotel bookings?

    Yes. In addition to deals on Knoxville to Brazil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Brazil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Brazil.

  • Can I find deals for business class flights from Knoxville to Brazil?

    Yes. Cheapflights offers flight deals from Knoxville to Brazil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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