Brazil

$587+ Cheap flights from Knoxville (TYS) to Brazil

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GRU
Dec 21 — Dec 281
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Brazil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Brazil

Keep the following information in mind while searching for Knoxville to Brazil flight deals. Data was last updated November 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,029
(KAYAK)

One-way from

$587
(123 Milhas)
Provider with most accurate pricing for Knoxville McGhee Tyson-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sao Paulo (SAO) flights.
From Knoxville McGhee Tyson to Brazil
One-way flight from Knoxville McGhee Tyson to Brazil

Find flight deals from Knoxville to Brazil

Cheapest flights from Knoxville to Brazil
Explore the most affordable flight options available from Knoxville to Brazil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:27 pmTYS - GRU
2 stops50h 43mMultiple Airlines
Sat 11/2912:55 pmGRU - TYS
1 stop25h 35mMultiple Airlines
Deal found 11/19$1,304
This Expedia deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:57 pmTYS - GRU
3 stops27h 03mLATAM Airlines
Mon 1/127:45 pmGRU - TYS
2 stops30h 00mLATAM Airlines
Deal found 11/20$1,400
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/121:05 pmTYS - GRU
1 stop16h 05mMultiple Airlines
Mon 1/127:45 pmGRU - TYS
2 stops46h 12mMultiple Airlines
Deal found 11/20$1,577
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:03 pmTYS - GRU
1 stop13h 02mAmerican Airlines
Mon 1/1211:30 pmGRU - TYS
1 stop19h 36mAmerican Airlines
Deal found 11/20$1,595
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:37 pmTYS - GRU
1 stop14h 53mUnited Airlines
Sat 11/2910:25 pmGRU - TYS
1 stop14h 23mUnited Airlines
Deal found 11/19$1,845
This KAYAK deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:53 pmTYS - GRU
2 stops22h 37mLATAM Airlines
Sat 11/2910:20 amGRU - TYS
2 stops15h 21mLATAM Airlines
Deal found 11/19$1,932

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Brazil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Knoxville to Brazil that are best for you.

Fly from

Knoxville

Fly to

Brazil

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:41 pm-8:00 pm

2 stops23h 19m

Sao Paulo Guarulhos Intl

Wed 4/1

11:45 pm-11:44 pm

2 stops24h 59m

$1,029

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

4:06 pm-5:40 am

1 stop11h 34m

Sao Paulo Guarulhos Intl

Wed 4/1

10:50 pm-1:26 pm

1 stop15h 36m

$1,080

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 2/19

6:41 pm-9:35 am

1 stop12h 54m

Sao Paulo Guarulhos Intl

Mon 2/23

7:35 am-11:50 pm

2 stops18h 15m

$1,140

KnoxvilleCuritiba

TYS - CWB

TYSCWB

Knoxville McGhee Tyson

Thu 3/26

4:00 pm-9:15 am

2 stops16h 15m

Curitiba Afonso Pena

Sun 3/29

7:25 pm-6:14 pm

2 stops23h 49m

$1,196

KnoxvilleCuritiba

TYS - CWB

TYSCWB

Knoxville McGhee Tyson

Sun 2/15

2:37 pm-5:15 pm

2 stops24h 38m

Curitiba Afonso Pena

Wed 2/18

7:10 am-11:10 am

2 stops30h 00m

$1,213

KnoxvilleCuritiba

TYS - CWB

TYSCWB

Knoxville McGhee Tyson

Sun 2/15

4:55 pm-2:25 pm

2 stops19h 30m

Curitiba Afonso Pena

Wed 2/18

7:00 pm-1:46 pm

2 stops20h 46m

$1,286

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 3/27

7:20 pm-9:35 am

1 stop13h 15m

$587

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 3/27

7:00 am-10:20 am

2 stops26h 20m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Best time to book a flight from Knoxville to Brazil

Have a flexible travel schedule? Discover the best time to fly to Brazil from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Brazil

What is the cheapest time of day to fly from TYS to BR?

Find hourly flight availability from Knoxville to Brazil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2025.

One of the essential ways to save on airfare from Knoxville to Brazil is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 35% on airfare.

Reviews of airlines servicing Brazil

Get insights into the airlines that provide service to Brazil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brazil. Reviews last updated November 21, 2025.
Get a feel of what it's like to fly with United Airlines from Knoxville to Brazil by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.6

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Food

6.6

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Brazil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Brazil?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Brazil. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Brazil?

    Airlines like LATAM Airlines, Delta, and United Airlines fly from Knoxville to Brazil in about 11h 34m. The time it takes to get you to your destination can typically vary by up to 11h 45m. The distance between Knoxville and Brazil is about 4768 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Knoxville to Brazil that include hotel bookings?

    Yes. In addition to deals on Knoxville to Brazil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Brazil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Brazil.

  • Can I find deals for business class flights from Knoxville to Brazil?

    Yes. Cheapflights offers flight deals from Knoxville to Brazil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Brazil

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.