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Biloxi

$259+ Cheap flights from Iowa to Biloxi, MS

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Iowa to Biloxi

Cheapest flights from Iowa to Biloxi
Explore the most affordable flight options available from Iowa to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:08 pmOMA - GPT
1 stop6h 32mDelta
Thu 1/16:00 amGPT - OMA
1 stop4h 54mDelta
Deal found 12/20$354
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:30 pmCID - GPT
1 stop4h 57mAmerican Airlines
Sat 1/35:58 pmGPT - CID
1 stop5h 12mAmerican Airlines
Deal found 12/19$381
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:55 pmOMA - GPT
2 stops7h 42mUnited Airlines
Thu 1/15:15 pmGPT - OMA
1 stop5h 07mUnited Airlines
Deal found 12/20$480
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:09 pmDSM - GPT
1 stop5h 18mAmerican Airlines
Sun 1/44:48 pmGPT - DSM
1 stop7h 49mAmerican Airlines
Deal found 12/19$485
This Delta deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:25 amCID - GPT
2 stops9h 20mDelta
Sun 1/45:21 pmGPT - CID
1 stop4h 58mDelta
Deal found 12/18$494
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:30 amCID - GPT
1 stop7h 44mAmerican Airlines
Sun 1/45:19 amGPT - CID
1 stop7h 23mAmerican Airlines
Deal found 12/18$535
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:09 amOMA - GPT
2 stops9h 05mAmerican Airlines
Thu 1/112:35 pmGPT - OMA
2 stops9h 35mAmerican Airlines
Deal found 12/20$604
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:30 amCID - GPT
2 stops9h 33mUnited Airlines
Sun 1/41:57 pmGPT - CID
2 stops23h 53mUnited Airlines
Deal found 12/18$751

Find flight deals from Iowa to Biloxi

Keep the following information in mind while searching for Iowa to Biloxi flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$248
Provider with most accurate pricing for Des Moines-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Gulfport Biloxi Regional flights.
Search Deals
From Iowa to Biloxi
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($110 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Iowa to Biloxi that are best for you.

Fly from

Iowa

Fly to

Biloxi

Route

Depart

Return

Price

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Sun 1/18

4:12 pm-9:53 pm

1 stop5h 41m

Gulfport Biloxi Regional

Sun 1/25

6:08 pm-11:59 pm

1 stop5h 51m

$259

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Mon 2/9

4:25 pm-10:41 pm

1 stop6h 16m

Gulfport Biloxi Regional

Sat 2/14

6:07 am-1:17 pm

1 stop7h 10m

$269

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Wed 1/21

7:00 am-1:51 pm

1 stop6h 51m

Gulfport Biloxi Regional

Sat 1/24

10:21 am-3:14 pm

1 stop4h 53m

$269

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Wed 1/14

8:15 am-1:22 pm

1 stop5h 07m

Gulfport Biloxi Regional

Wed 1/21

1:57 pm-11:07 pm

2 stops9h 10m

$274

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Wed 1/21

8:00 am-7:48 pm

2 stops11h 48m

Gulfport Biloxi Regional

Sat 1/24

5:13 pm-10:21 pm

1 stop5h 08m

$274

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Tue 2/10

6:00 am-4:55 pm

2 stops10h 55m

Gulfport Biloxi Regional

Sat 2/14

6:07 am-1:17 pm

1 stop7h 10m

$274

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Wed 1/14

12:14 pm-10:41 pm

2 stops10h 27m

Gulfport Biloxi Regional

Wed 1/21

6:32 am-4:36 pm

2 stops10h 04m

$279

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Wed 1/21

12:14 pm-10:41 pm

2 stops10h 27m

Gulfport Biloxi Regional

Sat 1/24

6:32 am-5:49 pm

2 stops11h 17m

$279

OmahaGulfport

OMA - GPT

OMAGPT

Omaha Eppley Airfield

Sun 1/18

11:26 am-7:48 pm

2 stops8h 22m

Gulfport Biloxi Regional

Sun 1/25

5:13 pm-10:21 pm

1 stop5h 08m

$294

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Wed 4/22

5:50 pm-10:22 pm

1 stop4h 32m

Gulfport Biloxi Regional

Tue 4/28

7:27 am-12:14 pm

1 stop4h 47m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 21 results
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Best time to book a flight from Iowa to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Biloxi

What is the cheapest month to book a flight from Iowa to Biloxi?

Currently, November is the cheapest month in which you can book a flight from Iowa to Biloxi (average of $100). Flying from Iowa to Biloxi in June is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to B1L?

Find hourly flight availability from Iowa to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2025.

It’s typically best to fly out from Iowa to Biloxi in the evening. Doing so could potentially save you 46% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Biloxi?

    Departing from Iowa to Biloxi will take you 6h 16m. Airlines will cover a distance of 810 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Biloxi?

    While some choose either Des Moines - Gulfport Biloxi Regional or Omaha Eppley Airfield - Gulfport Biloxi Regional, Cedar Rapids - Gulfport Biloxi Regional is the most popular route from Iowa to Biloxi.

  • Can I find deals for flights from Iowa to Biloxi that include hotel bookings?

    Yes. In addition to deals on Iowa to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Biloxi.

  • Can I find deals for business class flights from Iowa to Biloxi?

    Yes. Cheapflights offers flight deals from Iowa to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Biloxi?

    Currently, November is the cheapest month in which you can book a flight from Iowa to Biloxi (average of $100). Flying from Iowa to Biloxi in June is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Biloxi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Iowa to Biloxi

Discover the top 5 airlines that operate flights from Iowa to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$114Average$194FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$236Average$373FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$347FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$428FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$277Average$404FlexibilityNo cancel feeOn-time63%

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