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$396+ Cheap flights from Knoxville (TYS) to Istanbul (IST)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$883
(KLM)

One-way from

$396
(Kiwi.com)

Popular in

October

Cheapest in

November

Average price

$1,115
From Knoxville McGhee Tyson to Istanbul
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One-way flight from Knoxville McGhee Tyson to Istanbul
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Highest demand for flights based on searches. 7% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($112 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This KLM deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/284:13 pmTYS - IST
2 stops17h 07mKLM
Sun 10/54:20 amIST - TYS
2 stops19h 43mKLM
Deal found 8/14$883
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:08 pmTYS - IST
2 stops26h 17mDelta
Sat 10/115:05 pmIST - TYS
2 stops30h 26mDelta
Deal found 8/14$1,056
This Expedia deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/143:04 pmTYS - IST
2 stops26h 36mBritish Airways
Wed 8/205:35 pmIST - TYS
2 stops34h 20mBritish Airways
Deal found 8/13$1,089
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:10 amTYS - IST
1 stop27h 05mMultiple Airlines
Sat 10/118:35 pmIST - TYS
2 stops44h 21mMultiple Airlines
Deal found 8/14$1,160
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/287:00 amTYS - IST
1 stop26h 35mMultiple Airlines
Sun 10/56:55 pmIST - TYS
1 stop24h 00mMultiple Airlines
Deal found 8/14$1,261
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:00 amTYS - IST
3 stops27h 00mUnited Airlines
Sat 10/117:15 amIST - TYS
2 stops34h 14mUnited Airlines
Deal found 8/14$1,289
This Air Canada deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/42:16 pmTYS - IST
3 stops19h 54mAir Canada
Sat 10/118:30 pmIST - TYS
3 stops31h 41mAir Canada
Deal found 8/14$1,458

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 9/28

4:13 pm-4:20 pm

2 stops17h 07m

Istanbul

Sun 10/5

4:20 am-5:03 pm

2 stops19h 43m

$883

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 10/4

6:08 pm-3:25 am

2 stops26h 17m

Istanbul

Sat 10/11

5:05 pm-4:31 pm

2 stops30h 26m

$1,056

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 10/4

7:10 am-5:15 pm

1 stop27h 05m

Istanbul

Sat 10/11

8:35 pm-9:56 am

2 stops44h 21m

$1,160

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 9/28

7:00 am-4:35 pm

1 stop26h 35m

Istanbul

Sun 10/5

6:55 pm-11:55 am

1 stop24h 00m

$1,261

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 10/4

7:00 am-5:00 pm

3 stops27h 00m

Istanbul

Sat 10/11

7:15 am-10:29 am

2 stops34h 14m

$1,289

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 10/4

2:16 pm-5:10 pm

3 stops19h 54m

Istanbul

Sat 10/11

8:30 pm-9:11 pm

3 stops31h 41m

$1,458

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 8/29

2:00 pm-5:00 pm

2 stops20h 00m

Istanbul

Sun 8/31

5:55 pm-10:45 pm

2 stops35h 50m

$1,522

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 9/11

6:19 pm-7:25 pm

3 stops42h 06m

$396

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul Airport

What is the cheapest time of day to fly from TYS to IST?

Find hourly flight availability from Knoxville to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 16% on flights from Knoxville to Istanbul Airport by exploring options for tickets at noon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated August 14, 2025.
See what other customers who have flown with Delta, Air France, and United Airlines from Knoxville to Istanbul Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.4
Good
1,468 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
British Airways
6.7
Okay
7,266 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Istanbul. On average, McGhee Tyson has 0 outbound flights to Istanbul per day from 6 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines flying from Knoxville to Istanbul Airport round-trip?

    Our cheapest airline available from Knoxville to Istanbul Airport is Lufthansa. Our recent data shows that you can find tickets from as low as $648 on this airline. Additional options worth looking into are American Airlines and British Airways, starting at $770 and $833 round-trip. You may be able to fly from Knoxville to Istanbul Airport for 49% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul Airport?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Istanbul Airport (average of $923). Flying from Knoxville to Istanbul Airport in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Alternative routes for Knoxville to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Istanbul flights
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Chattanooga to Istanbul flights

Top 6 airlines flying from Knoxville to Istanbul

Discover the top 6 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$648Average$1,231FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$770Average$1,173FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$833Average$1,071FlexibilityNo cancel feeOn-time70%
DeltaCheapest$953Average$1,185FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$987Average$1,180FlexibilityNo cancel feeOn-time69%
Air FranceCheapest$2,396Average$2,396FlexibilityNo cancel feeOn-time77%

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