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$570+ Cheap flights from Knoxville (TYS) to Istanbul (IST)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Mar 9 — Mar 161
Mon 3/9
Mon 3/16
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.

This Justfly.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:20 pm
TYS
-
IST
2 stops38h 40m
Lufthansa
Tue 5/53:45 am
IST
-
TYS
2 stops23h 27m
Lufthansa
Deal found 2/6$570
This Lufthansa deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:20 pm
TYS
-
IST
2 stops19h 15m
Lufthansa
Tue 5/53:45 am
IST
-
TYS
2 stops23h 27m
Lufthansa
Deal found 2/6$578
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:52 pm
TYS
-
IST
2 stops24h 33m
Lufthansa
Mon 5/43:45 am
IST
-
TYS
2 stops23h 27m
Lufthansa
Deal found 2/6$583
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:15 pm
TYS
-
IST
2 stops45h 20m
United Airlines
Wed 5/65:40 am
IST
-
TYS
2 stops22h 05m
United Airlines
Deal found 2/6$584
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:20 pm
TYS
-
IST
2 stops38h 40m
Lufthansa
Mon 5/43:45 am
IST
-
TYS
2 stops23h 27m
Lufthansa
Deal found 2/6$588
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:54 pm
TYS
-
IST
2 stops26h 36m
Delta
Mon 5/45:20 pm
IST
-
TYS
2 stops30h 48m
Delta
Deal found 2/6$589
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:20 pm
TYS
-
IST
2 stops43h 15m
Lufthansa
Thu 5/71:55 pm
IST
-
TYS
2 stops37h 17m
Lufthansa
Deal found 2/6$594
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:48 pm
TYS
-
IST
2 stops25h 17m
Lufthansa
Thu 5/73:45 am
IST
-
TYS
2 stops23h 27m
Lufthansa
Deal found 2/6$622
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:48 pm
TYS
-
IST
2 stops25h 17m
Lufthansa
Thu 5/71:55 pm
IST
-
TYS
2 stops37h 17m
Lufthansa
Deal found 2/6$627
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:00 am
TYS
-
IST
2 stops23h 00m
United Airlines
Mon 5/45:50 am
IST
-
TYS
2 stops21h 06m
United Airlines
Deal found 2/6$628
This Justfly.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:52 pm
TYS
-
IST
2 stops24h 33m
Lufthansa
Mon 4/131:55 pm
IST
-
TYS
2 stops39h 43m
Lufthansa
Deal found 2/5$636
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:20 pm
TYS
-
IST
2 stops38h 40m
Lufthansa
Sun 5/33:45 am
IST
-
TYS
2 stops23h 27m
Lufthansa
Deal found 2/6$638

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$570
(Justfly.com)

Popular in

June

Cheapest in

February

Average price

$554
Provider with most accurate pricing for Knoxville McGhee Tyson-Istanbul flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Istanbul flights.
Search Deals
From Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($304 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 4/25

7:20 pm-5:00 pm

2 stops38h 40m

Istanbul

Tue 5/5

3:45 am-8:12 pm

2 stops23h 27m

$570

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 4/27

9:40 am-1:00 pm

2 stops20h 20m

Istanbul

Wed 5/6

5:40 am-8:45 pm

2 stops22h 05m

$578

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 4/26

7:20 pm-9:35 pm

2 stops19h 15m

Istanbul

Mon 5/4

3:45 am-8:12 pm

2 stops23h 27m

$578

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 4/26

7:20 pm-9:35 pm

2 stops19h 15m

Istanbul

Tue 5/5

3:45 am-8:12 pm

2 stops23h 27m

$578

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 4/27

1:52 pm-9:25 pm

2 stops24h 33m

Istanbul

Thu 5/7

3:45 am-8:12 pm

2 stops23h 27m

$583

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 4/27

1:52 pm-9:25 pm

2 stops24h 33m

Istanbul

Mon 5/4

3:45 am-8:12 pm

2 stops23h 27m

$583

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 4/26

7:20 pm-9:35 pm

2 stops19h 15m

Istanbul

Thu 5/7

3:45 am-8:12 pm

2 stops23h 27m

$583

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 4/27

7:00 am-1:00 pm

2 stops23h 00m

Istanbul

Thu 5/7

1:55 pm-10:49 am

2 stops27h 54m

$584

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 4/26

7:00 am-1:00 pm

2 stops23h 00m

Istanbul

Thu 5/7

1:55 pm-10:49 am

2 stops27h 54m

$584

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 4/25

5:15 pm-9:35 pm

2 stops45h 20m

Istanbul

Wed 5/6

5:40 am-8:45 pm

2 stops22h 05m

$584

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/6

Showing 1-10 of 12 results
1
2

Compare providers for flights from Knoxville to Istanbul

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Istanbul in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Istanbul Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Istanbul Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Istanbul Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated February 7, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Istanbul Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,162 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,162 reviews
Delta
7.9
Good
8,162 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,245 reviews
Delta
7.9
Good
8,162 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,248 reviews
Delta
7.9
Good
8,162 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,719 reviews
Delta
7.9
Good
8,162 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Istanbul. On average, McGhee Tyson has 0 outbound flights to Istanbul per day from 4 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Istanbul Airport?

    For as low as $578, Lufthansa can have you in Istanbul Airport from Knoxville in 20h 20m. The distance from Knoxville to Istanbul Airport is about 5617 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Istanbul Airport round-trip?

    Our cheapest airline available from Knoxville to Istanbul Airport is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. You may be able to fly from Knoxville to Istanbul Airport for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Alternative routes for Knoxville to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Istanbul flights
Nashville to Sabiha Gokcen flights
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Knoxville to Sabiha Gokcen flights

Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,102FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,208FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,061Average$1,316FlexibilityNo cancel feeOn-timeN/A

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