HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Istanbul

$629+ Cheap flights from Knoxville (TYS) to Istanbul (IST)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Istanbul with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:00 am
TYS
-
IST
2 stops29h 25m
United Airlines
Wed 4/85:40 am
IST
-
TYS
2 stops24h 23m
United Airlines
Deal found 2/15$629
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/189:40 am
TYS
-
IST
2 stops30h 05m
United Airlines
Wed 3/256:30 am
IST
-
TYS
2 stops39h 20m
United Airlines
Deal found 2/16$685
This KLM deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:00 pm
TYS
-
IST
2 stops19h 55m
Multiple Airlines
Tue 3/104:50 am
IST
-
TYS
2 stops25h 13m
Multiple Airlines
Deal found 2/13$741
This Justfly.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:16 am
TYS
-
IST
2 stops27h 59m
Lufthansa
Mon 8/173:45 am
IST
-
TYS
2 stops27h 14m
Lufthansa
Deal found 2/15$767
This Justfly.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:35 pm
TYS
-
IST
2 stops18h 40m
Lufthansa
Mon 9/143:45 am
IST
-
TYS
2 stops27h 14m
Lufthansa
Deal found 2/15$807
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:25 pm
TYS
-
IST
2 stops19h 20m
United Airlines
Sun 3/16:30 am
IST
-
TYS
2 stops22h 07m
United Airlines
Deal found 2/15$1,014
This KAYAK deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:50 pm
TYS
-
IST
2 stops20h 15m
Lufthansa
Sun 2/226:30 am
IST
-
TYS
2 stops22h 07m
Lufthansa
Deal found 2/16$1,015
This KAYAK deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/22:21 pm
TYS
-
IST
2 stops19h 34m
Lufthansa
Fri 3/66:30 am
IST
-
TYS
2 stops20h 59m
Lufthansa
Deal found 2/17$1,016
This lastminute.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:57 pm
TYS
-
IST
2 stops26h 33m
Multiple Airlines
Sat 5/165:20 pm
IST
-
TYS
2 stops31h 07m
Multiple Airlines
Deal found 2/16$1,032
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1710:18 am
TYS
-
IST
2 stops23h 27m
American Airlines
Tue 2/247:35 am
IST
-
TYS
2 stops19h 37m
American Airlines
Deal found 2/16$1,047
This BusinessClass deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:21 pm
TYS
-
IST
2 stops19h 44m
Lufthansa
Sat 2/217:00 pm
IST
-
TYS
2 stops32h 29m
Lufthansa
Deal found 2/15$1,050
This Air Canada deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:40 am
TYS
-
IST
3 stops24h 05m
Air Canada
Tue 3/1011:35 am
IST
-
TYS
3 stops30h 14m
Air Canada
Deal found 2/13$1,115

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$629
(United Airlines)

Popular in

June

Cheapest in

February

Average price

$554
Provider with most accurate pricing for Knoxville McGhee Tyson-Istanbul flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Istanbul flights.
Search Deals
From Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($308 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($47 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 4/1

9:00 am-9:25 pm

2 stops29h 25m

Istanbul

Wed 4/8

5:40 am-11:03 pm

2 stops24h 23m

$629

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 3/18

9:40 am-10:45 pm

2 stops30h 05m

Istanbul

Wed 3/25

6:30 am-2:50 pm

2 stops39h 20m

$685

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/3

1:00 pm-4:55 pm

2 stops19h 55m

Istanbul

Tue 3/10

4:50 am-11:03 pm

2 stops25h 13m

$741

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 8/11

10:16 am-9:15 pm

2 stops27h 59m

Istanbul

Mon 8/17

3:45 am-11:59 pm

2 stops27h 14m

$767

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 3/2

2:21 pm-5:55 pm

2 stops19h 34m

Istanbul

Fri 3/6

6:30 am-7:29 pm

2 stops20h 59m

$1,016

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 5/14

5:57 pm-3:30 am

2 stops26h 33m

Istanbul

Sat 5/16

5:20 pm-5:27 pm

2 stops31h 07m

$1,032

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/3

9:40 am-5:45 pm

3 stops24h 05m

Istanbul

Tue 3/10

11:35 am-10:49 am

3 stops30h 14m

$1,115

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 7/17

7:20 pm-1:20 am

2 stops23h 00m

Istanbul

Sun 7/26

6:00 am-4:34 pm

2 stops17h 34m

$1,135

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 3/2

7:15 am-6:30 am

1 stop15h 15m

Istanbul

Fri 3/6

8:15 am-6:58 pm

2 stops42h 43m

$1,157

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 3/18

8:30 am-1:25 pm

2 stops21h 55m

Istanbul

Wed 3/25

3:35 pm-1:02 pm

1 stop28h 27m

$1,166

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/15

Showing 1-10 of 11 results
1
2

Compare providers for flights from Knoxville to Istanbul

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Istanbul in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Istanbul Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Istanbul Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Istanbul Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated February 18, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Istanbul Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,208 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,208 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,312 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,304 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,751 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Istanbul. On average, McGhee Tyson has 0 outbound flights to Istanbul per day from 4 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Istanbul Airport?

    For as low as $767, United Airlines can have you in Istanbul Airport from Knoxville in 27h 59m. The distance from Knoxville to Istanbul Airport is about 5617 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Istanbul Airport round-trip?

    Our cheapest airline available from Knoxville to Istanbul Airport is United Airlines. Our recent data shows that you can find tickets from as low as $628 on this airline. Additional options worth looking into are British Airways and American Airlines, starting at $758 and $770 round-trip. You may be able to fly from Knoxville to Istanbul Airport for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Istanbul flights
Nashville to Sabiha Gokcen flights
Knoxville to Sabiha Gokcen flights
Chattanooga to Istanbul flights

Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,016FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,208FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,061Average$1,316FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.