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$256+ Cheap flights from Knoxville (TYS) to Istanbul (IST)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Best flights from Knoxville to Istanbul
Discover carefully curated flight deals from Knoxville to Istanbul that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:21 pmTYS - IST
2 stops19h 44mUnited Airlines
Mon 2/236:30 amIST - TYS
2 stops25h 14mUnited Airlines
Deal found 12/25$577
This Ethiopian Air deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ethiopian Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:21 pmTYS - IST
3 stops30h 39mEthiopian Air
Mon 2/2311:55 pmIST - TYS
3 stops47h 20mEthiopian Air
Deal found 12/25$3,173
This oojo deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/107:54 amTYS - IST
2 stops29h 11mRoyal Jordanian
Thu 1/152:20 amIST - TYS
2 stops27h 49mRoyal Jordanian
Deal found 12/26$4,608
This Air Canada deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/109:30 amTYS - IST
3 stops24h 35mAir Canada
Fri 1/166:30 amIST - TYS
3 stops20h 57mAir Canada
Deal found 12/26$12,025

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$561
(oojo)

One-way from

$256
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$799
Provider with most accurate pricing for Knoxville McGhee Tyson-Istanbul flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Istanbul flights.
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From Knoxville McGhee Tyson to Istanbul
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One-way flight from Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($321 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/19

2:21 pm-6:05 pm

2 stops19h 44m

Istanbul

Mon 2/23

6:30 am-11:44 pm

2 stops25h 14m

$577

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/19

2:21 pm-5:00 am

3 stops30h 39m

Istanbul

Mon 2/23

11:55 pm-3:15 pm

3 stops47h 20m

$3,173

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 1/10

7:54 am-9:05 pm

2 stops29h 11m

Istanbul

Thu 1/15

2:20 am-10:09 pm

2 stops27h 49m

$4,608

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 1/10

9:30 am-6:05 pm

3 stops24h 35m

Istanbul

Fri 1/16

6:30 am-7:27 pm

3 stops20h 57m

$12,025

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 2/6

12:55 pm-9:05 pm

2 stops24h 10m

$256

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/5

1:39 pm-9:05 pm

3 stops47h 26m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Compare providers for flights from Knoxville to Istanbul

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Istanbul in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Istanbul Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Istanbul Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Istanbul Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul Airport

What is the cheapest month to book a flight from Knoxville to Istanbul Airport?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul Airport (average of $554). Flying from Knoxville to Istanbul Airport in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IST?

Find hourly flight availability from Knoxville to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 15% on flights from Knoxville to Istanbul Airport by exploring options for tickets at noon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated December 28, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Istanbul Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,021 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,021 reviews
Delta
7.9
Good
8,021 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,116 reviews
Delta
7.9
Good
8,021 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,069 reviews
Delta
7.9
Good
8,021 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,614 reviews
Delta
7.9
Good
8,021 reviews

Entertainment

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Istanbul. On average, McGhee Tyson has 0 outbound flights to Istanbul per day from 4 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Istanbul Airport?

    For as low as $577, United Airlines can have you in Istanbul Airport from Knoxville in 19h 44m. The distance from Knoxville to Istanbul Airport is about 5617 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Istanbul Airport round-trip?

    Our cheapest airline available from Knoxville to Istanbul Airport is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. You may be able to fly from Knoxville to Istanbul Airport for 27% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul Airport?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul Airport (average of $554). Flying from Knoxville to Istanbul Airport in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Alternative routes for Knoxville to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,170FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,252FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,040Average$1,185FlexibilityNo cancel feeOn-timeN/A

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