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$576+ Cheap flights from Knoxville (TYS) to Istanbul (IST)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$576
(British Airways)

Popular in

December

Cheapest in

February

Average price

$945
Provider with most accurate pricing for Knoxville McGhee Tyson-Istanbul flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Istanbul flights.
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From Knoxville McGhee Tyson to Istanbul
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:53 pmTYS - IST
2 stops17h 02mKLM
Mon 11/174:50 amIST - TYS
2 stops20h 01mKLM
Deal found 10/27$738
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:25 pmTYS - IST
2 stops24h 20mLufthansa
Tue 11/186:30 amIST - TYS
2 stops22h 03mLufthansa
Deal found 10/27$759
This Air Canada deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/119:50 amTYS - IST
3 stops24h 35mAir Canada
Tue 11/188:50 amIST - TYS
3 stops23h 09mAir Canada
Deal found 10/27$781
This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:57 pmTYS - IST
2 stops16h 58mKLM
Wed 12/174:50 amIST - TYS
2 stops23h 10mKLM
Deal found 10/27$793
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:10 amTYS - IST
2 stops29h 35mUnited Airlines
Thu 12/187:55 amIST - TYS
2 stops19h 56mUnited Airlines
Deal found 10/27$840
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:50 amTYS - IST
2 stops27h 55mUnited Airlines
Thu 12/187:55 amIST - TYS
2 stops24h 04mUnited Airlines
Deal found 10/26$915
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:40 pmTYS - IST
2 stops17h 45mBritish Airways
Fri 12/198:10 amIST - TYS
2 stops21h 48mBritish Airways
Deal found 10/27$1,019
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:15 amTYS - IST
1 stop26h 55mMultiple Airlines
Thu 12/183:00 pmIST - TYS
2 stops29h 00mMultiple Airlines
Deal found 10/27$1,229
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:15 amTYS - IST
3 stops27h 10mMultiple Airlines
Fri 12/192:00 pmIST - TYS
2 stops32h 55mMultiple Airlines
Deal found 10/27$1,283
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/23:59 pmTYS - IST
2 stops27h 51mDelta
Sun 11/95:55 pmIST - TYS
2 stops34h 05mDelta
Deal found 10/28$1,548

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 1/8

7:44 am-1:10 am

2 stops33h 26m

Istanbul

Fri 1/23

8:10 am-10:09 pm

2 stops21h 59m

$576

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 11/11

3:53 pm-4:55 pm

2 stops17h 02m

Istanbul

Mon 11/17

4:50 am-4:51 pm

2 stops20h 01m

$738

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 11/11

2:25 pm-10:45 pm

2 stops24h 20m

Istanbul

Tue 11/18

6:30 am-8:33 pm

2 stops22h 03m

$759

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 11/11

9:50 am-6:25 pm

3 stops24h 35m

Istanbul

Tue 11/18

8:50 am-11:59 pm

3 stops23h 09m

$781

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 12/8

3:57 pm-4:55 pm

2 stops16h 58m

Istanbul

Wed 12/17

4:50 am-8:00 pm

2 stops23h 10m

$793

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 1/8

2:37 pm-4:55 pm

2 stops18h 18m

Istanbul

Thu 1/22

4:50 am-5:54 pm

2 stops21h 04m

$793

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 12/8

9:10 am-10:45 pm

2 stops29h 35m

Istanbul

Thu 12/18

7:55 am-7:51 pm

2 stops19h 56m

$840

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 12/11

10:50 am-10:45 pm

2 stops27h 55m

Istanbul

Thu 12/18

7:55 am-11:59 pm

2 stops24h 04m

$915

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 12/12

3:40 pm-5:25 pm

2 stops17h 45m

Istanbul

Fri 12/19

8:10 am-9:58 pm

2 stops21h 48m

$1,019

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 3/27

7:25 pm-6:05 pm

2 stops15h 40m

Istanbul

Tue 3/31

2:00 pm-11:59 pm

2 stops16h 59m

$1,125

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 12 results
1
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Compare providers for flights from Knoxville to Istanbul

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Istanbul in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Istanbul Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Istanbul Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Istanbul Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul Airport

What is the cheapest month to book a flight from Knoxville to Istanbul Airport?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul Airport (average of $554). Flying from Knoxville to Istanbul Airport in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IST?

Find hourly flight availability from Knoxville to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 15% on flights from Knoxville to Istanbul Airport by exploring options for tickets at noon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated October 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Istanbul Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
9,001 reviews
Delta
7.9
Good
7,994 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Lufthansa
6.8
Okay
7,538 reviews
Delta
7.9
Good
7,994 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
British Airways
6.7
Okay
7,483 reviews
Delta
7.9
Good
7,994 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Istanbul. On average, McGhee Tyson has 0 outbound flights to Istanbul per day from 5 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Istanbul Airport?

    For as low as $738, British Airways can have you in Istanbul Airport from Knoxville in 17h 02m. The distance from Knoxville to Istanbul Airport is about 5617 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Istanbul Airport round-trip?

    Our cheapest airline available from Knoxville to Istanbul Airport is Lufthansa. Our recent data shows that you can find tickets from as low as $648 on this airline. Additional options worth looking into are British Airways and American Airlines, starting at $758 and $770 round-trip. You may be able to fly from Knoxville to Istanbul Airport for 41% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul Airport?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul Airport (average of $554). Flying from Knoxville to Istanbul Airport in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Alternative routes for Knoxville to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
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Chattanooga to Istanbul flights

Top 5 airlines flying from Knoxville to Istanbul

Discover the top 5 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$648Average$1,231FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,173FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,180FlexibilityNo cancel feeOn-time69%
DeltaCheapest$954Average$1,185FlexibilityNo cancel feeOn-timeN/A

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