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$578+ Cheap flights from Knoxville (TYS) to Istanbul (IST)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/114:02 pm
TYS
-
IST
2 stops18h 23m
British Airways
Wed 3/187:35 am
IST
-
TYS
2 stops20h 30m
British Airways
Deal found 2/9$578
This KLM deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:00 pm
TYS
-
IST
2 stops19h 55m
Multiple Airlines
Tue 3/104:50 am
IST
-
TYS
2 stops26h 07m
Multiple Airlines
Deal found 2/10$740
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:21 pm
TYS
-
IST
2 stops24h 24m
United Airlines
Sun 3/16:30 am
IST
-
TYS
2 stops35h 42m
United Airlines
Deal found 2/10$778
This BusinessClass deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:20 pm
TYS
-
IST
2 stops19h 05m
Lufthansa
Sun 9/205:55 pm
IST
-
TYS
2 stops37h 04m
Lufthansa
Deal found 2/12$924
This BusinessClass deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm
TYS
-
IST
2 stops25h 05m
Scandinavian Airlines
Thu 9/34:25 am
IST
-
TYS
2 stops20h 52m
Scandinavian Airlines
Deal found 2/12$930
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:40 am
TYS
-
IST
2 stops25h 25m
United Airlines
Thu 3/196:30 am
IST
-
TYS
2 stops35h 19m
United Airlines
Deal found 2/10$938
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:21 pm
TYS
-
IST
2 stops19h 44m
Lufthansa
Wed 2/256:30 am
IST
-
TYS
2 stops22h 07m
Lufthansa
Deal found 2/10$984
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:00 am
TYS
-
IST
2 stops23h 00m
United Airlines
Sat 4/45:50 am
IST
-
TYS
2 stops24h 51m
United Airlines
Deal found 2/11$1,014
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:05 am
TYS
-
IST
2 stops31h 40m
Lufthansa
Thu 3/56:30 am
IST
-
TYS
2 stops22h 17m
Lufthansa
Deal found 2/9$1,015
This Air Canada deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:40 am
TYS
-
IST
3 stops24h 25m
Air Canada
Wed 2/256:30 am
IST
-
TYS
3 stops20h 59m
Air Canada
Deal found 2/10$1,025
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:38 pm
TYS
-
IST
2 stops25h 47m
Delta
Fri 4/34:25 am
IST
-
TYS
2 stops26h 32m
Delta
Deal found 2/9$1,053

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$578
(Expedia)

Popular in

June

Cheapest in

February

Average price

$554
Provider with most accurate pricing for Knoxville McGhee Tyson-Istanbul flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Istanbul flights.
Search Deals
From Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($304 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 3/11

4:02 pm-5:25 pm

2 stops18h 23m

Istanbul

Wed 3/18

7:35 am-9:05 pm

2 stops20h 30m

$578

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/3

1:00 pm-4:55 pm

2 stops19h 55m

Istanbul

Tue 3/10

4:50 am-11:57 pm

2 stops26h 07m

$740

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 2/25

9:40 am-6:05 pm

2 stops24h 25m

Istanbul

Sun 3/1

6:30 am-10:12 am

2 stops35h 42m

$778

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 3/30

7:20 pm-9:25 pm

2 stops19h 05m

Istanbul

Sun 9/20

5:55 pm-11:59 pm

2 stops37h 04m

$924

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/12

9:40 am-6:05 pm

2 stops25h 25m

Istanbul

Thu 3/19

6:30 am-10:49 am

2 stops35h 19m

$938

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 3/28

7:00 am-1:00 pm

2 stops23h 00m

Istanbul

Sat 4/4

5:50 am-11:41 pm

2 stops24h 51m

$1,014

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 3/27

6:38 pm-3:25 am

2 stops25h 47m

Istanbul

Fri 4/3

4:25 am-11:57 pm

2 stops26h 32m

$1,053

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 3/11

9:40 am-6:05 pm

3 stops25h 25m

Istanbul

Wed 3/18

6:30 am-10:49 am

3 stops35h 19m

$1,057

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/12

6:30 am-7:30 am

1 stop18h 00m

Istanbul

Thu 3/19

8:30 am-5:22 pm

1 stop15h 52m

$1,071

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/3

9:40 am-5:45 pm

3 stops24h 05m

Istanbul

Tue 3/10

11:35 am-10:49 am

3 stops30h 14m

$1,110

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Compare providers for flights from Knoxville to Istanbul

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Istanbul in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Istanbul Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Istanbul Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Istanbul Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated February 13, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Istanbul Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,192 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,192 reviews
Delta
7.9
Good
8,192 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,285 reviews
Delta
7.9
Good
8,192 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,276 reviews
Delta
7.9
Good
8,192 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,737 reviews
Delta
7.9
Good
8,192 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Istanbul. On average, McGhee Tyson has 0 outbound flights to Istanbul per day from 4 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Istanbul Airport?

    For as low as $578, British Airways can have you in Istanbul Airport from Knoxville in 18h 23m. The distance from Knoxville to Istanbul Airport is about 5617 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Istanbul Airport round-trip?

    Our cheapest airline available from Knoxville to Istanbul Airport is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. You may be able to fly from Knoxville to Istanbul Airport for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Alternative routes for Knoxville to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,016FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,208FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,061Average$1,316FlexibilityNo cancel feeOn-timeN/A

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