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Italy

$423+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Aug 25 — Sep 11
Tue 8/25
Tue 9/1
1 adult, Economy
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Cheap flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.

This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:59 pm
TYS
-
MXP
1 stop17h 21m
United Airlines
Wed 10/79:45 am
MXP
-
TYS
1 stop17h 00m
United Airlines
Deal found 7/23$776
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:59 pm
TYS
-
MXP
1 stop17h 21m
United Airlines
Tue 8/2512:20 pm
MXP
-
TYS
2 stops32h 17m
United Airlines
Deal found 7/21$793
This oojo deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:45 am
TYS
-
BLQ
2 stops30h 55m
Lufthansa
Tue 8/256:05 am
BLQ
-
TYS
2 stops20h 19m
Lufthansa
Deal found 7/21$795
This United deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:40 am
TYS
-
MXP
1 stop20h 40m
Multiple Airlines
Tue 8/2512:20 pm
MXP
-
TYS
3 stops38h 04m
Multiple Airlines
Deal found 7/21$798
This Air Canada deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:20 pm
TYS
-
MXP
2 stops33h 00m
Air Canada
Wed 8/2612:20 pm
MXP
-
TYS
2 stops32h 17m
Air Canada
Deal found 7/21$802
This FlightHub deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:20 pm
TYS
-
BLQ
2 stops15h 10m
Lufthansa
Tue 8/2510:30 am
BLQ
-
TYS
2 stops15h 54m
Lufthansa
Deal found 7/21$806
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:16 pm
TYS
-
FLR
2 stops18h 19m
United Airlines
Wed 11/42:20 pm
FLR
-
TYS
2 stops36h 34m
United Airlines
Deal found 7/22$807
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:20 pm
TYS
-
FCO
1 stop11h 55m
United Airlines
Wed 8/2611:30 am
FCO
-
TYS
2 stops31h 47m
United Airlines
Deal found 7/21$809
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:57 am
TYS
-
MXP
1 stop21h 08m
American Airlines
Tue 8/251:20 pm
MXP
-
TYS
1 stop16h 31m
American Airlines
Deal found 7/21$813
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:15 am
TYS
-
BLQ
2 stops23h 35m
United Airlines
Fri 8/2810:30 am
BLQ
-
TYS
2 stops19h 29m
United Airlines
Deal found 7/21$813
This Cheapflightsfares deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:20 pm
TYS
-
LIN
2 stops16h 25m
Lufthansa
Tue 8/256:50 am
LIN
-
TYS
2 stops19h 34m
Lufthansa
Deal found 7/21$814
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:40 am
TYS
-
MXP
1 stop20h 40m
United Airlines
Wed 8/2611:20 am
MXP
-
TYS
2 stops18h 39m
United Airlines
Deal found 7/21$815

Find flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated July 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$775
(United Airlines)

One-way from

$423
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$1,191
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Italy
Search Deals
One-way flight from Knoxville McGhee Tyson to Italy
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($355 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($57 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 1/17

2:20 pm-8:30 am

1 stop12h 10m

Rome Fiumicino

Wed 1/20

1:15 pm-8:54 pm

2 stops37h 39m

$775
Quickest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 1/13

7:35 pm-4:30 pm

2 stops14h 55m

Florence Peretola

Wed 1/20

10:20 am-7:17 pm

2 stops14h 57m

$776

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Tue 9/22

10:45 am-1:20 pm

1 stop20h 35m

Milan Malpensa

Wed 10/7

11:20 am-11:59 pm

2 stops18h 39m

$779

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 1/10

7:00 am-8:55 am

2 stops19h 55m

Rome Fiumicino

Wed 1/27

7:05 am-7:17 pm

2 stops18h 12m

$797

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 1/18

8:30 am-7:55 am

1 stop17h 25m

Rome Fiumicino

Mon 2/8

2:20 pm-7:17 pm

2 stops34h 57m

$805

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

10:42 am-4:35 pm

2 stops23h 53m

Florence Peretola

Wed 11/4

2:20 pm-5:02 pm

2 stops32h 42m

$807

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 8/19

7:20 pm-1:15 pm

1 stop11h 55m

Rome Fiumicino

Wed 8/26

11:30 am-1:17 pm

2 stops31h 47m

$809

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Tue 8/18

6:02 pm-1:20 pm

1 stop13h 18m

Milan Malpensa

Fri 8/28

3:20 pm-1:18 pm

1 stop27h 58m

$819

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 8/19

1:00 pm-1:20 pm

2 stops18h 20m

Milan Malpensa

Fri 8/28

10:40 am-11:59 pm

2 stops19h 19m

$822

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Sun 10/4

5:45 am-7:30 am

2 stops19h 45m

Milan Malpensa

Sun 10/11

11:20 am-11:59 pm

2 stops18h 39m

$844

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/25

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Italy (average of $684). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated July 26, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Italy have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,489 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,489 reviews
Delta
7.8
Good
8,489 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,041 reviews
Delta
7.8
Good
8,489 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,845 reviews
Delta
7.8
Good
8,489 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Lufthansa
6.8
Okay
8,157 reviews
Delta
7.8
Good
8,489 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
British Airways
6.7
Okay
8,132 reviews
Delta
7.8
Good
8,489 reviews

Overall

7.8

Comfort

7.8

Entertainment

7.8

Crew

8.5

Boarding

8.1

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Knoxville to Italy?

    There are many flights that can get you from Knoxville to Italy in 12h 10m. Fly via United Airlines, Lufthansa, or Delta to get the fastest option. Airlines will cover a distance of 4908 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Milan Malpensa and Knoxville McGhee Tyson - Milan Linate.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Italy (average of $684). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Italy

Discover the top 4 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$501Average$974FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$582Average$867FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$592Average$1,109FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$787Average$1,270FlexibilityNo cancel feeOn-time76%

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