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Italy

$360+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Aug 19 — Aug 261
Wed 8/19
Wed 8/26
1 adult, Economy
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Cheap flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.

This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:00 pm
TYS
-
FCO
1 stop11h 45m
United Airlines
Wed 1/137:05 am
FCO
-
TYS
2 stops18h 29m
United Airlines
Deal found 7/17$788
This oojo deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:38 am
TYS
-
FCO
1 stop19h 22m
British Airways
Wed 12/231:00 pm
FCO
-
TYS
1 stop27h 24m
British Airways
Deal found 7/19$791
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:38 am
TYS
-
FCO
1 stop19h 22m
American Airlines
Wed 12/231:00 pm
FCO
-
TYS
1 stop27h 24m
American Airlines
Deal found 7/19$795
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:00 am
TYS
-
FCO
2 stops19h 30m
United Airlines
Wed 12/237:05 am
FCO
-
TYS
2 stops33h 25m
United Airlines
Deal found 7/19$798
This oojo deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:20 pm
TYS
-
FLR
2 stops18h 55m
Lufthansa
Wed 8/2610:20 am
FLR
-
TYS
2 stops16h 04m
Lufthansa
Deal found 7/17$800
This oojo deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:20 pm
TYS
-
FCO
2 stops16h 55m
Lufthansa
Tue 8/256:50 am
FCO
-
TYS
2 stops19h 34m
Lufthansa
Deal found 7/16$801
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:42 am
TYS
-
FLR
2 stops23h 53m
United Airlines
Wed 11/42:20 pm
FLR
-
TYS
2 stops32h 42m
United Airlines
Deal found 7/16$802
This United deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:00 am
TYS
-
FCO
2 stops19h 30m
Multiple Airlines
Wed 12/231:15 pm
FCO
-
TYS
2 stops51h 15m
Multiple Airlines
Deal found 7/19$803
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:00 pm
TYS
-
FCO
1 stop13h 15m
United Airlines
Wed 8/2611:30 am
FCO
-
TYS
2 stops35h 28m
United Airlines
Deal found 7/16$804
This Air Canada deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:45 am
TYS
-
FCO
2 stops21h 30m
Air Canada
Thu 8/2711:30 am
FCO
-
TYS
2 stops38h 54m
Air Canada
Deal found 7/19$807
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:45 am
TYS
-
VCE
1 stop16h 10m
United Airlines
Mon 8/242:50 pm
VCE
-
TYS
2 stops32h 08m
United Airlines
Deal found 7/18$815
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:45 am
TYS
-
FLR
2 stops24h 50m
United Airlines
Mon 8/2410:45 am
FLR
-
TYS
2 stops36h 13m
United Airlines
Deal found 7/20$819

Find flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated July 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$788
(United Airlines)

One-way from

$360
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$1,191
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Italy
Search Deals
One-way flight from Knoxville McGhee Tyson to Italy
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($368 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($59 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 12/9

2:20 pm-8:30 am

1 stop12h 10m

Rome Fiumicino

Wed 1/13

11:00 am-7:17 pm

1 stop14h 17m

$790

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 8/17

1:00 pm-8:15 am

1 stop13h 15m

Rome Fiumicino

Wed 8/26

11:30 am-4:58 pm

2 stops35h 28m

$804

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 8/19

1:00 pm-8:15 am

1 stop13h 15m

Rome Fiumicino

Tue 8/25

12:25 pm-8:24 pm

2 stops37h 59m

$808

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Mon 8/17

9:45 am-7:55 am

1 stop16h 10m

Venice Marco Polo

Mon 8/24

2:50 pm-4:58 pm

2 stops32h 08m

$815

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Tue 8/18

9:45 am-4:35 pm

2 stops24h 50m

Florence Peretola

Mon 8/24

10:45 am-4:58 pm

2 stops36h 13m

$819

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 8/18

7:20 pm-1:15 pm

1 stop11h 55m

Rome Fiumicino

Fri 8/28

6:50 am-11:59 pm

2 stops23h 09m

$822

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 8/18

9:45 am-8:15 am

1 stop16h 30m

Rome Fiumicino

Wed 8/26

3:20 pm-11:59 pm

1 stop14h 39m

$824

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 12/13

7:13 pm-5:50 pm

2 stops16h 37m

Rome Fiumicino

Wed 12/23

8:30 pm-8:43 pm

2 stops30h 13m

$827

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Tue 8/18

6:02 pm-1:20 pm

1 stop13h 18m

Milan Malpensa

Mon 8/24

11:20 am-11:59 pm

2 stops42h 39m

$830

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Tue 8/18

6:02 pm-5:45 pm

2 stops17h 43m

Milan Linate

Mon 8/24

7:30 pm-8:24 pm

2 stops30h 54m

$841

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/20

Showing 1-10 of 54 resultsSorted by cheapest first
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6

Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Italy (average of $686). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated July 20, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Italy have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,476 reviews

Comfort

7.8

Crew

8.5

Food

7.2

Overall

7.8

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,476 reviews
Delta
7.8
Good
8,476 reviews

Comfort

7.8

Crew

8.5

Food

7.2

Overall

7.8

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,014 reviews
Delta
7.8
Good
8,476 reviews

Comfort

7.8

Crew

8.5

Food

7.2

Overall

7.8

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,827 reviews
Delta
7.8
Good
8,476 reviews

Comfort

7.8

Crew

8.5

Food

7.2

Overall

7.8

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Lufthansa
6.8
Okay
8,150 reviews
Delta
7.8
Good
8,476 reviews

Comfort

7.8

Crew

8.5

Food

7.2

Overall

7.8

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
British Airways
6.7
Okay
8,124 reviews
Delta
7.8
Good
8,476 reviews

Comfort

7.8

Crew

8.5

Food

7.2

Overall

7.8

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Knoxville to Italy?

    There are many flights that can get you from Knoxville to Italy in 12h 10m. Fly via United Airlines, Lufthansa, or KLM to get the fastest option. Airlines will cover a distance of 4908 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Milan Malpensa and Knoxville McGhee Tyson - Venice Marco Polo.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Italy (average of $686). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Italy

Discover the top 4 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$501Average$974FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$582Average$867FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$592Average$1,109FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$787Average$1,270FlexibilityNo cancel feeOn-time76%

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