HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$443+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This oojo deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/93:41 pm
TYS
-
FCO
1 stop12h 39m
British Airways
Tue 8/251:30 pm
FCO
-
TYS
1 stop15h 28m
British Airways
Deal found 4/28$786
This FlightHub deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:00 pm
TYS
-
FCO
2 stops34h 50m
Scandinavian Airlines
Mon 10/1211:55 am
FCO
-
TYS
2 stops39h 50m
Scandinavian Airlines
Deal found 4/24$809
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:57 pm
TYS
-
BLQ
2 stops22h 43m
United Airlines
Tue 8/181:30 pm
BLQ
-
TYS
2 stops37h 18m
United Airlines
Deal found 4/27$827
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am
TYS
-
FLR
2 stops19h 15m
United Airlines
Wed 11/41:15 pm
FLR
-
TYS
2 stops36h 02m
United Airlines
Deal found 4/24$831
This oojo deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:23 pm
TYS
-
FLR
2 stops26h 57m
British Airways
Wed 11/412:10 pm
FLR
-
TYS
2 stops38h 54m
British Airways
Deal found 4/28$838
This Gotogate deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:45 am
TYS
-
FCO
2 stops24h 00m
Air Canada
Tue 8/2511:30 am
FCO
-
TYS
2 stops29h 06m
Air Canada
Deal found 4/28$842
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:21 am
TYS
-
FCO
1 stop18h 44m
British Airways
Sun 11/17:50 am
FCO
-
TYS
2 stops19h 14m
British Airways
Deal found 4/26$894
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:39 pm
TYS
-
MXP
2 stops15h 06m
American Airlines
Fri 9/251:20 pm
MXP
-
TYS
1 stop16h 11m
American Airlines
Deal found 4/26$906
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:45 am
TYS
-
VCE
1 stop20h 10m
United Airlines
Tue 9/229:40 am
VCE
-
TYS
1 stop20h 17m
United Airlines
Deal found 4/24$910
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:20 pm
TYS
-
MXP
2 stops16h 15m
Delta
Thu 9/2411:40 am
MXP
-
TYS
1 stop18h 07m
Delta
Deal found 4/25$914
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:20 pm
TYS
-
MXP
2 stops16h 15m
Delta
Tue 9/229:00 am
MXP
-
TYS
2 stops17h 42m
Delta
Deal found 4/25$918
This Cheapflightsfares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:57 pm
TYS
-
VCE
2 stops18h 03m
Lufthansa
Tue 9/226:40 am
VCE
-
TYS
2 stops23h 17m
Lufthansa
Deal found 4/24$918

Find flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$786
(oojo)

One-way from

$443
(Kiwi.com)

Popular in

May

Cheapest in

December

Average price

$845
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Italy
Search Deals
One-way flight from Knoxville McGhee Tyson to Italy
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($233 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleBologna

TYS - BLQ

TYSBLQ

Knoxville McGhee Tyson

Tue 8/11

5:57 pm-10:40 pm

2 stops22h 43m

Bologna Guglielmo Marconi

Tue 8/18

1:30 pm-8:48 pm

2 stops37h 18m

$827

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

9:45 am-11:00 am

2 stops19h 15m

Florence Peretola

Wed 11/4

1:15 pm-7:17 pm

2 stops36h 02m

$831

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/21

1:23 pm-10:20 pm

2 stops26h 57m

Florence Peretola

Wed 11/4

12:10 pm-9:04 pm

2 stops38h 54m

$838

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Sun 9/13

7:20 pm-5:35 pm

2 stops16h 15m

Milan Malpensa

Thu 9/24

11:40 am-11:47 pm

1 stop18h 07m

$914

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Sun 9/13

7:20 pm-5:35 pm

2 stops16h 15m

Milan Malpensa

Tue 9/22

9:00 am-8:42 pm

2 stops17h 42m

$918

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Mon 9/14

5:57 pm-1:55 pm

2 stops13h 58m

Milan Linate

Fri 9/25

6:40 am-4:34 pm

2 stops15h 54m

$921

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Sun 9/13

7:20 pm-7:45 pm

2 stops18h 25m

Milan Linate

Thu 9/24

6:40 am-9:28 pm

2 stops20h 48m

$921

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Sun 9/13

7:19 pm-7:30 am

2 stops30h 11m

Milan Malpensa

Thu 9/24

11:20 am-11:55 pm

2 stops18h 35m

$928

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 9/9

5:57 pm-1:20 pm

1 stop13h 23m

Milan Malpensa

Mon 9/21

11:20 am-4:59 pm

2 stops35h 39m

$933

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Mon 9/14

5:45 am-7:30 am

2 stops19h 45m

Milan Malpensa

Fri 9/25

12:20 pm-2:37 pm

2 stops32h 17m

$951

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Showing 1-10 of 51 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Italy (average of $467). Flying from Knoxville to Italy in June is currently the most expensive (average of $872). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated April 29, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Italy have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,467 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,467 reviews
Delta
7.9
Good
8,467 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,680 reviews
Delta
7.9
Good
8,467 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,680 reviews
Delta
7.9
Good
8,467 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,959 reviews
Delta
7.9
Good
8,467 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,931 reviews
Delta
7.9
Good
8,467 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Knoxville to Italy?

    There are many flights that can get you from Knoxville to Italy in 16h 15m. Fly via United Airlines, British Airways, or Delta to get the fastest option. Airlines will cover a distance of 4624 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Milan Malpensa and Knoxville McGhee Tyson - Milan Linate.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Italy (average of $467). Flying from Knoxville to Italy in June is currently the most expensive (average of $872). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Knoxville to Italy

Discover the top 4 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$582Average$918FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$592Average$1,061FlexibilityNo cancel feeOn-time70%
DeltaCheapest$660Average$928FlexibilityNo cancel feeOn-timeN/A
LufthansaCheapest$787Average$986FlexibilityNo cancel feeOn-time76%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.