$464+ Cheap flights from Italy to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — TYS
Dec 11 — Dec 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Italy to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Italy to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Italy to KnoxvilleExplore the most affordable flight options available from Italy to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
Explore the most affordable flight options available from Italy to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops20h 00m
Tue 12/2910:11 am -
2 stops17h 24m
Deal found 11/7![Delta logo]()
$890
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:25 am -
1 stop29h 36m
Sat 12/267:25 am -
1 stop20h 10m
Deal found 11/7![Delta logo]()
$891
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:00 am -
1 stop33h 42m
Sat 1/99:45 am -
2 stops22h 15m
Deal found 11/9![United Airlines logo]()
$1,037
This Justfly.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:05 am -
3 stops18h 42m
Tue 12/291:30 pm -
3 stops18h 30m
Deal found 11/7![Air Canada logo]()
$2,533
This Air Canada deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1211:15 am -
2 stops18h 44m
Tue 12/299:30 am -
3 stops17h 10m
Deal found 11/7![Multiple Airlines logo]()
$2,574
This Air Canada deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:55 am -
3 stops20h 20m
Sat 1/910:45 am -
2 stops18h 10m
Deal found 11/9![Multiple Airlines logo]()
$2,999
This Ethiopian Air deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ethiopian Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:00 pm -
3 stops50h 49m
Sat 1/92:04 pm -
3 stops32h 31m
Deal found 11/9![Ethiopian Air logo]()
$3,366
This Cathay Pacific deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:40 am -
3 stops42h 59m
Sat 12/262:55 pm -
3 stops47h 15m
Deal found 11/7![Multiple Airlines logo]()
$14,777
Best flights from Italy to KnoxvilleDiscover carefully curated flight deals from Italy to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
Discover carefully curated flight deals from Italy to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1610:55 am -
2 stops29h 05m
Tue 4/208:30 am -
2 stops23h 20m
Deal found 11/7![United Airlines logo]()
$861
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/216:25 am -
2 stops20h 56m
Sun 4/253:58 pm -
2 stops14h 07m
Deal found 11/10![American Airlines logo]()
$868
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops20h 00m
Sat 12/267:25 am -
1 stop20h 10m
Deal found 11/7![Delta logo]()
$890
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2110:55 am -
2 stops18h 24m
Sun 4/258:30 am -
1 stop18h 35m
Deal found 11/10![United Airlines logo]()
$868
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/166:25 am -
2 stops19h 35m
Tue 4/202:49 pm -
1 stop13h 06m
Deal found 11/6![American Airlines logo]()
$878
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops20h 00m
Tue 12/296:50 am -
1 stop21h 40m
Deal found 11/7![Delta logo]()
$890
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:00 am -
1 stop33h 42m
Sat 1/99:45 am -
2 stops22h 15m
Deal found 11/9![United Airlines logo]()
$1,037
This Air Canada deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:55 am -
3 stops20h 20m
Sat 1/910:45 am -
2 stops18h 10m
Deal found 11/9![Multiple Airlines logo]()
$2,999
This Ethiopian Air deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ethiopian Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:00 pm -
3 stops50h 49m
Sat 1/92:04 pm -
3 stops32h 31m
Deal found 11/9![Ethiopian Air logo]()
$3,366
This Cathay Pacific deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:40 am -
3 stops42h 59m
Sat 12/262:55 pm -
3 stops47h 15m
Deal found 11/7![Multiple Airlines logo]()
$14,777
Last-minute flights from Italy to KnoxvilleDiscover last-minute flight deals from Italy to Knoxville. Data last updated November 11, 2026 and is based on user searches.
Discover last-minute flight deals from Italy to Knoxville. Data last updated November 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops20h 00m
Tue 12/2910:11 am -
2 stops17h 24m
Deal found 11/7![Delta logo]()
$890
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:25 am -
1 stop29h 36m
Sat 12/267:25 am -
1 stop20h 10m
Deal found 11/7![Delta logo]()
$891
This Justfly.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:05 am -
3 stops18h 42m
Tue 12/291:30 pm -
3 stops18h 30m
Deal found 11/7![Air Canada logo]()
$2,533
This Air Canada deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1211:15 am -
2 stops18h 44m
Tue 12/299:30 am -
3 stops17h 10m
Deal found 11/7![Multiple Airlines logo]()
$2,574
This Cathay Pacific deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:40 am -
3 stops42h 59m
Sat 12/262:55 pm -
3 stops47h 15m
Deal found 11/7![Multiple Airlines logo]()
$14,777
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:00 am -
1 stop33h 42m
Sat 1/99:45 am -
2 stops22h 15m
Deal found 11/9![United Airlines logo]()
$1,037
This Air Canada deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:55 am -
3 stops20h 20m
Sat 1/910:45 am -
2 stops18h 10m
Deal found 11/9![Multiple Airlines logo]()
$2,999
This Ethiopian Air deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ethiopian Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:00 pm -
3 stops50h 49m
Sat 1/92:04 pm -
3 stops32h 31m
Deal found 11/9![Ethiopian Air logo]()
$3,366
One-way flights from Italy to KnoxvilleSearch for one-way flight options from Italy to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 11, 2026.
Search for one-way flight options from Italy to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:50 pm -
3 stops56h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:55 am -
3 stops47h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm -
3 stops47h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:15 am -
3 stops57h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$555
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:10 am -
3 stops32h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$620
This FlightHub deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:15 am -
2 stops37h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Aer Lingus logo]()
$644
Find flight deals from Italy to Knoxville
Keep the following information in mind while searching for Italy to Knoxville flight deals. Data was last updated November 11, 2026.
Round-trip from | $852 (Expedia) |
|---|---|
One-way from | $464 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Italy to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
Use the filters below to find and compare flights from Italy to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RomeKnoxville
FCO Rome Fiumicino - TYS Knoxville McGhee Tyson
FCOTYS
Rome Fiumicino
Mon 11/23
8:50 pm-11:28 pm
3 stops56h 38m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$464
RomeKnoxville
FCO Rome Fiumicino - TYS Knoxville McGhee Tyson
FCOTYS
Rome Fiumicino
Thu 11/19
6:10 am-8:39 am
3 stops32h 29m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$620
RomeKnoxville
FCO Rome Fiumicino - TYS Knoxville McGhee Tyson
FCOTYS
Rome Fiumicino
Wed 12/23
11:15 am-6:19 pm
2 stops37h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$644
RomeKnoxville
FCO Rome Fiumicino - TYS Knoxville McGhee Tyson
FCOTYS
Rome Fiumicino
Sun 11/22
10:10 am-10:04 pm
1 stop17h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$814
VeniceKnoxville
VCE Venice Marco Polo - TYS Knoxville McGhee Tyson
VCETYS
Venice Marco Polo
Fri 4/16
10:55 am-10:00 am
2 stops29h 05m
Knoxville McGhee Tyson
Tue 4/20
8:30 am-1:50 pm
2 stops23h 20m
$861
Quickest round-trip
RomeKnoxville
FCO Rome Fiumicino - TYS Knoxville McGhee Tyson
FCOTYS
Rome Fiumicino
Sat 11/21
11:00 am-8:50 pm
1 stop15h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$863
VeniceKnoxville
VCE Venice Marco Polo - TYS Knoxville McGhee Tyson
VCETYS
Venice Marco Polo
Wed 4/21
6:25 am-9:21 pm
2 stops20h 56m
Knoxville McGhee Tyson
Sun 4/25
3:58 pm-12:05 pm
2 stops14h 07m
$868
VeniceKnoxville
VCE Venice Marco Polo - TYS Knoxville McGhee Tyson
VCETYS
Venice Marco Polo
Wed 4/21
10:55 am-11:19 pm
2 stops18h 24m
Knoxville McGhee Tyson
Sun 4/25
8:30 am-9:05 am
1 stop18h 35m
$868
VeniceKnoxville
VCE Venice Marco Polo - TYS Knoxville McGhee Tyson
VCETYS
Venice Marco Polo
Fri 4/16
6:25 am-8:00 pm
2 stops19h 35m
Knoxville McGhee Tyson
Tue 4/20
2:49 pm-9:55 am
1 stop13h 06m
$878
RomeKnoxville
FCO Rome Fiumicino - TYS Knoxville McGhee Tyson
FCOTYS
Rome Fiumicino
Sat 12/12
6:00 am-8:00 pm
2 stops20h 00m
Knoxville McGhee Tyson
Sat 12/26
7:25 am-9:35 am
1 stop20h 10m
$890
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Italy to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Italy with our price prediction graph.
VCE-TYS
FCO-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Italy to Knoxville
IT0-TYS
VCE-TYS
FCO-TYS
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Italy to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Newport
Bryson City
Crossville
Morristown
Murphy
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Popular flights