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$297+ Cheap flights from Des Moines to Amarillo (DSM - AMA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — AMA
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Des Moines to Amarillo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$297
(United Airlines)
From Des Moines to Amarillo
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Cheapest flights from Des Moines to Amarillo
Explore the most affordable flight options available from Des Moines to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/48:15 amDSM - AMA
1 stop6h 03mUnited Airlines
lun. 12/83:25 pmAMA - DSM
1 stop7h 04mUnited Airlines
Deal found 9/16$297
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/45:25 pmDSM - AMA
1 stop6h 29mAmerican Airlines
lun. 12/84:11 pmAMA - DSM
2 stops7h 39mAmerican Airlines
Deal found 9/16$302
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:12 pmDSM - AMA
1 stop4h 49mAmerican Airlines
mar. 10/2112:36 pmAMA - DSM
1 stop5h 06mAmerican Airlines
Deal found 9/16$312
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/75:14 pmDSM - AMA
1 stop4h 24mUnited Airlines
mar. 11/115:45 pmAMA - DSM
1 stop5h 59mUnited Airlines
Deal found 9/15$352
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:39 pmDSM - AMA
1 stop4h 14mAmerican Airlines
mar. 11/1112:23 pmAMA - DSM
2 stops9h 45mAmerican Airlines
Deal found 9/15$378
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/13:31 pmDSM - AMA
1 stop4h 22mAmerican Airlines
lun. 12/86:47 pmAMA - DSM
1 stop4h 12mAmerican Airlines
Deal found 9/16$412
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:13 pmDSM - AMA
1 stop4h 28mUnited Airlines
vie. 10/35:27 pmAMA - DSM
1 stop6h 29mUnited Airlines
Deal found 9/16$427

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Des Moines

Fly to

Amarillo

Route

Depart

Return

Price

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

jue. 12/4

8:15 am-2:18 pm

1 stop6h 03m

Amarillo

lun. 12/8

3:25 pm-10:29 pm

1 stop7h 04m

$297

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

mar. 11/25

5:26 pm-11:55 pm

1 stop6h 29m

Amarillo

mar. 12/2

6:00 am-10:40 am

1 stop4h 40m

$297

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

jue. 12/4

5:25 pm-11:54 pm

1 stop6h 29m

Amarillo

lun. 12/8

4:11 pm-11:50 pm

2 stops7h 39m

$302

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

mar. 10/14

6:12 pm-11:01 pm

1 stop4h 49m

Amarillo

mar. 10/21

12:36 pm-5:42 pm

1 stop5h 06m

$312

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

vie. 11/7

5:14 pm-9:38 pm

1 stop4h 24m

Amarillo

mar. 11/11

5:45 pm-11:44 pm

1 stop5h 59m

$352

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

vie. 11/7

3:39 pm-7:53 pm

1 stop4h 14m

Amarillo

mar. 11/11

12:23 pm-10:08 pm

2 stops9h 45m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Des Moines to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Amarillo?

    There are many flights that can get you from Des Moines to Amarillo in 6h 03m. Fly via United Airlines or American Airlines to get the fastest option. There are 616 mi between Des Moines and Amarillo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Amarillo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Amarillo.

  • Can I find deals for business class flights from Des Moines to Amarillo?

    Yes. Cheapflights offers flight deals from Des Moines to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Amarillo?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Amarillo (average of $321). Flying from Des Moines to Amarillo in March is currently the most expensive (average of $418). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

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