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Amarillo

$397+ Cheap flights from Des Moines to Amarillo (DSM - AMA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — AMA
May 4 — May 111
Mon 5/4
Mon 5/11
1 adult, Economy
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Cheap flight deals from Des Moines to Amarillo

Cheapest flights from Des Moines to Amarillo
Explore the most affordable flight options available from Des Moines to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.

This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:28 am
DSM
-
AMA
1 stop5h 12m
United Airlines
Wed 4/293:04 pm
AMA
-
DSM
1 stop7h 39m
United Airlines
Deal found 3/30$397
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:06 pm
DSM
-
AMA
1 stop4h 11m
American Airlines
Sun 4/267:07 pm
AMA
-
DSM
1 stop4h 52m
American Airlines
Deal found 3/30$438
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:10 am
DSM
-
AMA
2 stops10h 45m
Southwest
Wed 6/241:00 pm
AMA
-
DSM
2 stops8h 40m
Southwest
Deal found 4/3$458
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/183:04 pm
DSM
-
AMA
1 stop7h 30m
United Airlines
Wed 4/225:19 pm
AMA
-
DSM
1 stop6h 23m
United Airlines
Deal found 4/3$467
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:56 am
DSM
-
AMA
2 stops9h 41m
American Airlines
Wed 4/225:00 am
AMA
-
DSM
1 stop6h 26m
American Airlines
Deal found 4/3$472
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/214:50 pm
DSM
-
AMA
1 stop7h 09m
American Airlines
Wed 6/247:06 pm
AMA
-
DSM
1 stop4h 53m
American Airlines
Deal found 4/3$523
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:20 pm
DSM
-
AMA
2 stops7h 05m
Southwest
Mon 4/2010:15 am
AMA
-
DSM
2 stops11h 40m
Southwest
Deal found 4/2$562

Find flight deals from Des Moines to Amarillo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$397
(United Airlines)
Provider with most accurate pricing for Des Moines-Amarillo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Amarillo flights.
Search Deals
From Des Moines to Amarillo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 4/28

11:28 am-4:40 pm

1 stop5h 12m

Amarillo

Wed 4/29

3:04 pm-10:43 pm

1 stop7h 39m

$397
Quickest round-trip

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 4/22

12:06 pm-4:17 pm

1 stop4h 11m

Amarillo

Sun 4/26

7:07 pm-11:59 pm

1 stop4h 52m

$438

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 4/18

3:04 pm-10:34 pm

1 stop7h 30m

Amarillo

Wed 4/22

5:19 pm-11:42 pm

1 stop6h 23m

$467

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 4/18

12:00 pm-9:42 pm

2 stops9h 42m

Amarillo

Wed 4/22

1:05 pm-11:49 pm

2 stops10h 44m

$477

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sun 6/21

4:50 pm-11:59 pm

1 stop7h 09m

Amarillo

Wed 6/24

7:06 pm-11:59 pm

1 stop4h 53m

$523

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Sorted by cheapest first

Compare providers for flights from Des Moines to Amarillo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Amarillo in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Amarillo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Amarillo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Amarillo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Amarillo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Amarillo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Amarillo?

    There are many flights that can get you from Des Moines to Amarillo in 5h 12m. Fly via United Airlines to get the fastest option. There are 616 mi between Des Moines and Amarillo.

  • Can I find deals for flights from Des Moines to Amarillo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Amarillo.

  • Can I find deals for business class flights from Des Moines to Amarillo?

    Yes. Cheapflights offers flight deals from Des Moines to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

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