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Amarillo

$347+ Cheap flights from Des Moines to Amarillo (DSM - AMA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — AMA
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheap flight deals from Des Moines to Amarillo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$347
(American Airlines)
Provider with most accurate pricing for Des Moines-Amarillo flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Amarillo flights.
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From Des Moines to Amarillo
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Find flight deals from Des Moines to Amarillo

Cheapest flights from Des Moines to Amarillo
Explore the most affordable flight options available from Des Moines to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:39 pmDSM - AMA
1 stop6h 15mAmerican Airlines
Thu 12/256:26 pmAMA - DSM
1 stop5h 09mAmerican Airlines
Deal found 11/4$347
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:52 pmDSM - AMA
1 stop7h 42mUnited Airlines
Sun 11/236:30 amAMA - DSM
1 stop7h 41mUnited Airlines
Deal found 11/2$417
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:53 pmDSM - AMA
2 stops10h 02mAmerican Airlines
Sun 11/2310:18 amAMA - DSM
1 stop4h 33mAmerican Airlines
Deal found 11/2$422
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:14 pmDSM - AMA
1 stop4h 24mUnited Airlines
Sun 11/235:45 pmAMA - DSM
1 stop5h 59mUnited Airlines
Deal found 11/4$447
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:00 amDSM - AMA
1 stop6h 51mAmerican Airlines
Sun 11/234:16 pmAMA - DSM
2 stops7h 28mAmerican Airlines
Deal found 11/4$452
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:20 amDSM - AMA
2 stops8h 55mSouthwest
Sun 11/235:50 amAMA - DSM
2 stops9h 40mSouthwest
Deal found 11/4$457
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:46 pmDSM - AMA
2 stops27h 48mUnited Airlines
Thu 12/257:35 amAMA - DSM
2 stops14h 05mUnited Airlines
Deal found 11/4$641

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Des Moines

Fly to

Amarillo

Route

Depart

Return

Price

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Mon 12/22

5:39 pm-11:54 pm

1 stop6h 15m

Amarillo

Thu 12/25

6:26 pm-11:35 pm

1 stop5h 09m

$347

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 3/31

3:30 pm-10:23 pm

1 stop6h 53m

Amarillo

Wed 4/1

5:05 am-12:05 pm

1 stop7h 00m

$367

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Fri 11/21

2:52 pm-10:34 pm

1 stop7h 42m

Amarillo

Sun 11/23

6:30 am-2:11 pm

1 stop7h 41m

$417

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Fri 11/21

1:53 pm-11:55 pm

2 stops10h 02m

Amarillo

Sun 11/23

10:18 am-2:51 pm

1 stop4h 33m

$422

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 11/19

2:52 pm-8:22 pm

1 stop5h 30m

Amarillo

Sun 11/23

3:14 pm-10:20 pm

1 stop7h 06m

$447

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 11/18

5:14 pm-9:38 pm

1 stop4h 24m

Amarillo

Sun 11/23

5:45 pm-11:44 pm

1 stop5h 59m

$447

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 11/18

5:00 am-11:51 am

1 stop6h 51m

Amarillo

Sun 11/23

4:16 pm-11:44 pm

2 stops7h 28m

$452

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 11/19

5:42 am-3:47 pm

2 stops10h 05m

Amarillo

Sun 11/23

12:23 pm-4:41 pm

1 stop4h 18m

$452

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Compare providers for flights from Des Moines to Amarillo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Amarillo in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Amarillo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Amarillo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Amarillo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Amarillo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Amarillo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Amarillo?

    There are many flights that can get you from Des Moines to Amarillo in 6h 15m. Fly via American Airlines or United Airlines to get the fastest option. There are 616 mi between Des Moines and Amarillo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Amarillo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Amarillo.

  • Can I find deals for business class flights from Des Moines to Amarillo?

    Yes. Cheapflights offers flight deals from Des Moines to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

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