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Amarillo

$364+ Cheap flights from Des Moines to Amarillo (DSM - AMA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — AMA
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Des Moines to Amarillo

Cheapest flights from Des Moines to Amarillo
Explore the most affordable flight options available from Des Moines to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:06 pmDSM - AMA
1 stop4h 43mUnited Airlines
Sun 1/45:35 pmAMA - DSM
1 stop6h 23mUnited Airlines
Deal found 12/16$386
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:09 pmDSM - AMA
1 stop5h 15mAmerican Airlines
Sun 1/45:00 amAMA - DSM
2 stops9h 53mAmerican Airlines
Deal found 12/16$465
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/223:28 pmDSM - AMA
1 stop6h 58mAmerican Airlines
Thu 12/2510:08 amAMA - DSM
1 stop6h 57mAmerican Airlines
Deal found 12/16$541

Find flight deals from Des Moines to Amarillo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$364
(United Airlines)
Provider with most accurate pricing for Des Moines-Amarillo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Amarillo flights.
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From Des Moines to Amarillo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Des Moines

Fly to

Amarillo

Route

Depart

Return

Price

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 1/17

3:04 pm-9:59 pm

1 stop6h 55m

Amarillo

Wed 1/21

3:20 pm-10:30 pm

1 stop7h 10m

$364

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Fri 1/30

4:00 pm-8:30 pm

1 stop4h 30m

Amarillo

Fri 2/6

6:38 pm-11:23 pm

1 stop4h 45m

$369

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 12/31

5:06 pm-9:49 pm

1 stop4h 43m

Amarillo

Sun 1/4

5:35 pm-11:58 pm

1 stop6h 23m

$386

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 1/3

5:40 am-4:25 pm

2 stops10h 45m

Amarillo

Sat 1/10

10:55 am-8:20 pm

2 stops9h 25m

$439

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 12/31

1:09 pm-6:24 pm

1 stop5h 15m

Amarillo

Sun 1/4

5:00 am-2:53 pm

2 stops9h 53m

$465

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Compare providers for flights from Des Moines to Amarillo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Amarillo in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Amarillo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Amarillo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Amarillo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Amarillo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Amarillo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Amarillo?

    There are many flights that can get you from Des Moines to Amarillo in 4h 30m. Fly via United Airlines or American Airlines to get the fastest option. There are 616 mi between Des Moines and Amarillo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Amarillo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Amarillo.

  • Can I find deals for business class flights from Des Moines to Amarillo?

    Yes. Cheapflights offers flight deals from Des Moines to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

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