HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Amarillo

$196+ Cheap flights from Des Moines to Amarillo (DSM - AMA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — AMA
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Amarillo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Amarillo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$427
(United Airlines)
From Des Moines to Amarillo
Search Deals

Find flight deals from Des Moines to Amarillo

Cheapest flights from Des Moines to Amarillo
Explore the most affordable flight options available from Des Moines to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:25 amDSM - AMA
2 stops9h 50mSouthwest
Wed 12/102:50 pmAMA - DSM
2 stops6h 45mSouthwest
Deal found 9/9$196
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:38 pmDSM - AMA
1 stop6h 54mAmerican Airlines
Wed 12/104:11 pmAMA - DSM
1 stop6h 48mAmerican Airlines
Deal found 9/9$288
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:13 pmDSM - AMA
1 stop4h 28mUnited Airlines
Sun 10/58:00 amAMA - DSM
1 stop4h 37mUnited Airlines
Deal found 9/9$331
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/232:58 pmDSM - AMA
1 stop7h 32mUnited Airlines
Fri 9/263:20 pmAMA - DSM
1 stop7h 08mUnited Airlines
Deal found 9/9$427
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2310:16 amDSM - AMA
2 stops12h 43mAmerican Airlines
Fri 9/266:48 pmAMA - DSM
1 stop4h 25mAmerican Airlines
Deal found 9/9$432
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:30 amDSM - AMA
2 stops9h 00mSouthwest
Fri 9/2612:55 pmAMA - DSM
2 stops9h 55mSouthwest
Deal found 9/9$437
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:12 pmDSM - AMA
1 stop4h 47mAmerican Airlines
Sun 10/55:00 amAMA - DSM
2 stops8h 51mAmerican Airlines
Deal found 9/9$450
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:15 amDSM - AMA
1 stop5h 11mUnited Airlines
Sat 9/273:20 pmAMA - DSM
1 stop7h 08mUnited Airlines
Deal found 9/10$487
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/215:11 amDSM - AMA
1 stop4h 35mAmerican Airlines
Sat 9/2710:16 amAMA - DSM
2 stops10h 05mAmerican Airlines
Deal found 9/10$492
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2111:55 amDSM - AMA
2 stops11h 55mSouthwest
Sat 9/2711:20 amAMA - DSM
2 stops9h 00mSouthwest
Deal found 9/10$640

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Des Moines

Fly to

Amarillo

Route

Depart

Return

Price

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 9/23

2:58 pm-10:30 pm

1 stop7h 32m

Amarillo

Fri 9/26

3:20 pm-10:28 pm

1 stop7h 08m

$427

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 9/23

10:16 am-10:59 pm

2 stops12h 43m

Amarillo

Fri 9/26

6:48 pm-11:13 pm

1 stop4h 25m

$432

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 9/23

6:30 am-3:30 pm

2 stops9h 00m

Amarillo

Fri 9/26

12:55 pm-10:50 pm

2 stops9h 55m

$437

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sun 9/21

6:15 am-11:26 am

1 stop5h 11m

Amarillo

Sat 9/27

3:20 pm-10:28 pm

1 stop7h 08m

$487

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sun 9/21

5:11 am-9:46 am

1 stop4h 35m

Amarillo

Sat 9/27

10:16 am-8:21 pm

2 stops10h 05m

$492

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sun 9/21

11:55 am-11:50 pm

2 stops11h 55m

Amarillo

Sat 9/27

11:20 am-8:20 pm

2 stops9h 00m

$640

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Des Moines to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Amarillo?

    There are many flights that can get you from Des Moines to Amarillo in 7h 32m. Fly via United Airlines, American Airlines, or Southwest to get the fastest option. There are 616 mi between Des Moines and Amarillo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Amarillo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Amarillo.

  • Can I find deals for business class flights from Des Moines to Amarillo?

    Yes. Cheapflights offers flight deals from Des Moines to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Amarillo?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Amarillo (average of $321). Flying from Des Moines to Amarillo in March is currently the most expensive (average of $418). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Amarillo

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Dallas/Fort Worth flights
Cedar Rapids to Dallas/Fort Worth flights
Des Moines to Dallas/Fort Worth flights
Omaha to Hobby flights
Des Moines to Hobby flights
Omaha to George Bush Intcntl flights
Des Moines to George Bush Intcntl flights
Cedar Rapids to Hobby flights
Omaha to Austin flights
Moline to Dallas/Fort Worth flights
Cedar Rapids to George Bush Intcntl flights
Omaha to Love Field flights
Omaha to San Antonio flights
Des Moines to Love Field flights
Cedar Rapids to Austin flights
Moline to Hobby flights
Des Moines to Austin flights
Cedar Rapids to McAllen flights
Moline to San Antonio flights
Moline to Austin flights
Moline to George Bush Intcntl flights
Cedar Rapids to Love Field flights
Cedar Rapids to San Antonio flights
Des Moines to San Antonio flights
Des Moines to El Paso flights
Moline to Love Field flights
Des Moines to Harlingen flights
Cedar Rapids to Corpus Christi flights
Des Moines to McAllen flights
Omaha to Harlingen flights
Omaha to Amarillo flights
Omaha to Brownsville flights
Des Moines to Brownsville flights
La Crosse to Dallas/Fort Worth flights
Omaha to McAllen flights
Moline to El Paso flights
Omaha to Corpus Christi flights
La Crosse to Hobby flights
Sioux City to Dallas/Fort Worth flights
Omaha to El Paso flights
Cedar Rapids to Harlingen flights
Waterloo to Dallas/Fort Worth flights
Moline to Corpus Christi flights
Moline to San Angelo flights
Moline to McAllen flights
Omaha to Lubbock flights
La Crosse to George Bush Intcntl flights
Waterloo to Hobby flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.