HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Amarillo

$250+ Cheap flights from Des Moines to Amarillo (DSM - AMA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — AMA
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Amarillo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Amarillo

Cheapest flights from Des Moines to Amarillo
Explore the most affordable flight options available from Des Moines to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:31 am
DSM
-
AMA
1 stop5h 01m
United Airlines
Tue 5/193:15 pm
AMA
-
DSM
1 stop7h 30m
United Airlines
Deal found 2/2$303
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:55 am
DSM
-
AMA
2 stops8h 20m
Southwest
Tue 5/197:00 am
AMA
-
DSM
2 stops7h 05m
Southwest
Deal found 2/2$313
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:09 pm
DSM
-
AMA
1 stop3h 54m
American Airlines
Mon 9/216:40 pm
AMA
-
DSM
1 stop3h 50m
American Airlines
Deal found 2/2$367
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:20 pm
DSM
-
AMA
2 stops7h 05m
Southwest
Sun 4/122:00 pm
AMA
-
DSM
2 stops8h 20m
Southwest
Deal found 2/3$377
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:00 am
DSM
-
AMA
2 stops10h 10m
Southwest
Mon 9/211:00 pm
AMA
-
DSM
2 stops9h 10m
Southwest
Deal found 2/2$397
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:06 pm
DSM
-
AMA
1 stop6h 31m
American Airlines
Tue 5/194:47 pm
AMA
-
DSM
2 stops7h 02m
American Airlines
Deal found 2/2$410
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:06 pm
DSM
-
AMA
1 stop4h 11m
American Airlines
Sun 4/127:07 pm
AMA
-
DSM
1 stop4h 52m
American Airlines
Deal found 2/3$414
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/177:52 am
DSM
-
AMA
1 stop6h 29m
United Airlines
Sat 2/219:05 am
AMA
-
DSM
1 stop5h 12m
United Airlines
Deal found 2/2$447
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:20 am
DSM
-
AMA
2 stops6h 40m
Southwest
Sat 2/212:20 pm
AMA
-
DSM
1 stop8h 05m
Southwest
Deal found 2/2$452
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:52 am
DSM
-
AMA
1 stop6h 29m
United Airlines
Sun 2/229:05 am
AMA
-
DSM
1 stop5h 12m
United Airlines
Deal found 2/3$491

Find flight deals from Des Moines to Amarillo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Amarillo (AMA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$303
(United Airlines)

One-way from

$250
(Southwest)
Provider with most accurate pricing for Des Moines-Amarillo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Amarillo flights.
Search Deals
From Des Moines to Amarillo
Search Deals
One-way flight from Des Moines to Amarillo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Des Moines

Fly to

Amarillo

Route

Depart

Return

Price

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 5/12

11:31 am-4:32 pm

1 stop5h 01m

Amarillo

Tue 5/19

3:15 pm-10:45 pm

1 stop7h 30m

$303

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 5/12

6:55 am-3:15 pm

2 stops8h 20m

Amarillo

Tue 5/19

7:00 am-2:05 pm

2 stops7h 05m

$313

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Thu 4/9

4:20 pm-11:25 pm

2 stops7h 05m

Amarillo

Sun 4/12

2:00 pm-10:20 pm

2 stops8h 20m

$377

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 5/12

12:06 pm-6:37 pm

1 stop6h 31m

Amarillo

Tue 5/19

4:47 pm-11:49 pm

2 stops7h 02m

$410

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Thu 4/9

12:06 pm-4:17 pm

1 stop4h 11m

Amarillo

Sun 4/12

7:07 pm-11:59 pm

1 stop4h 52m

$414

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 2/17

7:52 am-2:21 pm

1 stop6h 29m

Amarillo

Sat 2/21

9:05 am-2:17 pm

1 stop5h 12m

$447

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 2/17

5:20 am-12:00 pm

2 stops6h 40m

Amarillo

Sat 2/21

2:20 pm-10:25 pm

1 stop8h 05m

$452

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 2/18

7:52 am-2:21 pm

1 stop6h 29m

Amarillo

Sun 2/22

9:05 am-2:17 pm

1 stop5h 12m

$491

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Wed 2/18

8:35 am-4:30 pm

2 stops7h 55m

Amarillo

Sun 2/22

11:50 am-11:35 pm

2 stops11h 45m

$509

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 2/14

2:59 pm-11:29 am

1 stop20h 30m

Amarillo

Wed 2/18

5:31 pm-11:43 pm

1 stop6h 12m

$607

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 12 results
1
2

Compare providers for flights from Des Moines to Amarillo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Amarillo in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Amarillo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Amarillo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Amarillo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Amarillo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Amarillo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Amarillo?

    There are many flights that can get you from Des Moines to Amarillo in 5h 01m. Fly via United Airlines, Southwest, or American Airlines to get the fastest option. There are 616 mi between Des Moines and Amarillo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Amarillo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Amarillo.

  • Can I find deals for business class flights from Des Moines to Amarillo?

    Yes. Cheapflights offers flight deals from Des Moines to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Amarillo

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Dallas/Fort Worth flights
Des Moines to Dallas/Fort Worth flights
Omaha to Hobby flights
Omaha to George Bush Intcntl flights
Des Moines to Hobby flights
Cedar Rapids to Dallas/Fort Worth flights
Omaha to Love Field flights
Des Moines to George Bush Intcntl flights
Moline to Dallas/Fort Worth flights
Cedar Rapids to Hobby flights
Omaha to Austin flights
Des Moines to San Antonio flights
Cedar Rapids to San Antonio flights
Cedar Rapids to George Bush Intcntl flights
Des Moines to Love Field flights
Cedar Rapids to Austin flights
Des Moines to Austin flights
Omaha to San Antonio flights
Des Moines to McAllen flights
Moline to San Antonio flights
Moline to Love Field flights
Moline to Austin flights
Omaha to El Paso flights
Moline to Hobby flights
Omaha to Brownsville flights
Des Moines to Brownsville flights
Moline to George Bush Intcntl flights
Des Moines to El Paso flights
Cedar Rapids to Love Field flights
Cedar Rapids to McAllen flights
Cedar Rapids to Harlingen flights
Cedar Rapids to Brownsville flights
Cedar Rapids to Amarillo flights
Omaha to Harlingen flights
Omaha to Corpus Christi flights
La Crosse to Hobby flights
Des Moines to Harlingen flights
La Crosse to George Bush Intcntl flights
Omaha to McAllen flights
Sioux City to Austin flights
Cedar Rapids to Corpus Christi flights
Moline to El Paso flights
Waterloo to Dallas/Fort Worth flights
Sioux City to Dallas/Fort Worth flights
La Crosse to Dallas/Fort Worth flights
Cedar Rapids to El Paso flights
Moline to McAllen flights
Omaha to Amarillo flights
Cedar Rapids to Lubbock flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.