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Des Moines

$28+ Cheap flights from Des Moines

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — DEN
May 22 — May 291
Fri 5/22
Fri 5/29
1 adult, Economy
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Find flights from Des Moines within your budget

 
Find flights departing from Des Moines that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on April 22, 2026. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Wed 5/27

1:04 pm-10:58 pm

2 stops10h 54m

Denver Intl

Sat 5/30

9:12 am-3:44 pm

1 stop5h 32m

$221

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Sat 8/22

12:10 pm-8:10 pm

2 stops9h 00m

Denver Intl

Tue 8/25

6:30 am-11:50 am

1 stop4h 20m

$222

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 9/16

12:30 pm-5:35 pm

1 stop7h 05m

Phoenix Sky Harbor Intl

Sat 9/26

5:25 am-4:10 pm

1 stop8h 45m

$277

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

Wed 7/22

2:48 pm-9:51 pm

1 stop7h 03m

Houston Hobby

Tue 7/28

5:14 pm-10:29 pm

1 stop5h 15m

$289

Des MoinesHouston

DSM - IAH

DSMIAH

Des Moines

Fri 7/17

2:45 pm-9:35 pm

1 stop6h 50m

Houston George Bush Intcntl

Thu 7/30

10:49 am-4:53 pm

1 stop6h 04m

$289

Des MoinesHouston

DSM - IAH

DSMIAH

Des Moines

Fri 6/12

2:48 pm-9:23 pm

1 stop6h 35m

Houston George Bush Intcntl

Sun 6/14

6:30 am-2:05 pm

1 stop7h 35m

$289

Des MoinesHouston

DSM - IAH

DSMIAH

Des Moines

Thu 5/14

6:41 pm-11:54 pm

1 stop5h 13m

Houston George Bush Intcntl

Tue 5/19

4:28 pm-10:32 pm

1 stop6h 04m

$289

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Wed 5/20

7:01 am-1:59 pm

2 stops7h 58m

Denver Intl

Fri 5/22

12:55 am-10:16 am

2 stops8h 21m

$290

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

Sat 6/6

6:55 pm-12:45 am

1 stop5h 50m

Houston Hobby

Sat 6/13

5:00 am-11:35 am

1 stop6h 35m

$294

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

Wed 8/12

6:10 am-2:40 pm

2 stops8h 30m

Houston Hobby

Mon 8/17

3:20 pm-10:10 pm

2 stops6h 50m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 60 resultsSorted by cheapest first
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Compare providers for flights from Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines in April
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
Super.comPrice Accuracy-Trust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*2 stars
Trip.comPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: Among all the travel providers offering deals on flights from Des Moines, FlightHub has been found to have the most accurate pricing. Users can find the same prices on deals on Cheapflights as FlightHub about >95% of the time. This is based on searches for flights from Des Moines made on Cheapflights over the past month and is updated monthly.
  • Most trusted provider: In terms of trustworthiness, Cheapflights users rate FlightHub the highest out of those offering flight deals from Des Moines. FlightHub has a user feedback rating of 3 out of 3 stars (3 being the best) and has received the most positive sentiment from Cheapflights users searching for flights from Des Moines. This info is gathered from Cheapflights searches over the past month.

Best time to book a flight from Des Moines

Have a flexible travel schedule? Discover the best time to fly from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines

Get recent, data-driven insights about flights from Des Moines including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Denver. Price data was last updated on April 17, 2026.

To ensure you get the cheapest price possible for a flight from Des Moines, you should look to book at least 44 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines?

Currently, September is the cheapest month in which you can book a flight from Des Moines (average of $158). Flying from Des Moines in April will prove the most costly (average of $287). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

When is the cheapest time to fly from Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Denver. Price data was last updated on April 18, 2026.

Those who are seeking the cheapest fare on flights departing from Des Moines would be wise to consider leaving during Tuesday evenings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Sunday mornings when fares are usually the most expensive.

Which airlines fly from Des Moines?

For flights departing from Des Moines check dates and pricing for the following: Frontier, United Airlines, Southwest, JetBlue. These airlines depart to the following popular destinations: Denver.

American Airlines
American Airlines
From $148
United Airlines
United Airlines
From $118
Allegiant Air
Allegiant Air
From $53
Delta
Delta
From $85

What are popular destinations to fly to from Des Moines?

Some of the most frequent flights departing from Des Moines everyday are: Chicago (736 flights per day), Atlanta (164 flights per day), and Detroit (156 flights per day).

Chicago
Chicago
From $166
Denver Intl
Denver Intl
From $96
Atlanta Hartsfield-Jackson
Atlanta Hartsfield-Jackson
From $130
Phoenix Sky Harbor Intl
Phoenix Sky Harbor Intl
From $76

What is the cheapest place to fly to from Des Moines?

The cheapest city to fly to from Des Moines is Boston Logan Intl, with prices starting at $45. Explore other affordable destinations below.

Boston Logan Intl
Boston Logan Intl
From $45
Nashville Intl
Nashville Intl
From $45
Philadelphia
Philadelphia
From $49
Fort Lauderdale
Fort Lauderdale
From $56

Airline reviews for flights from Des Moines

Read reviews and ratings of airlines operating flights from Des Moines. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Des Moines travel. Please note that the reviews are sourced from user searches and were last updated on April 22, 2026. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Read reviews from past customers who have flown Southwest,United Airlines, andJetBlue from Des Moines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,327 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,327 reviews
Southwest
8.0
Very good
4,327 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,637 reviews
Southwest
8.0
Very good
4,327 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
JetBlue
7.2
Good
2,950 reviews
Southwest
8.0
Very good
4,327 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Frontier
5.7
Fair
2,981 reviews
Southwest
8.0
Very good
4,327 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

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Related info for your journey

Access useful and relevant information related to your journey from Des Moines. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated April 22, 2026.

  • What are the most popular destinations to fly to from Des Moines?

    This month, the top selected destinations from Des Moines are Las Vegas, Denver, Cancún. Throughout the year, Las Vegas, Denver, Los Angeles are some of the top choices made by users flying from Des Moines.

  • What is the cheapest flight from Des Moines to anywhere?

    Users have flown out of Des Moines for as low as $45 to Nashville (prices may vary depending on the airline and departure time). On average, users have booked flights for $399 to fly from Des Moines.

  • What are the cheapest airlines flying from Des Moines to anywhere?

    Over the past few days, we've found that Allegiant Air, Frontier, and Delta have the cheapest prices from Des Moines. Allegiant Air flights from Des Moines to Austin Bergstrom ($53), Frontier flights from Des Moines to Atlanta Hartsfield-Jackson ($62), and Delta flights from Des Moines to Allentown-Bethlehem ($85).

  • What is the cheapest premium economy flight from Des Moines?

    Options for some of the cheapest premium economy flights from Des Moines we have found on Cheapflights are as follows:
    Fly from Des Moines to Detroit Metropolitan Wayne County Airport starting at $667
    Fly from Des Moines to New York LaGuardia Airport starting at $739
    Fly from Des Moines to Minneapolis starting at $749
    Fly from Des Moines to Washington, D.C. Reagan-National Airport starting at $763

  • What is the cheapest first class flight from Des Moines?

    If you’re looking for a cheap first-class flight from Des Moines, consider Houston. Prices start at $555 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Des Moines?

    September is currently the cheapest month to fly from Des Moines. At this moment in time April is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Des Moines?

    Check out the cheapest flights from Des Moines to embark to:
    Fly from Des Moines to Nashville from $76 round trip
    Fly from Des Moines to Philadelphia from $85 round trip
    Fly from Des Moines to Fort Myers from $92 round trip
    Fly from Des Moines to Las Vegas from $95 round trip
    Fly from Des Moines to Denver from $111 round trip

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