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Syracuse

$321+ Cheap flights from Panama City (PTY) to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SYR
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Panama City to Syracuse

Cheapest flights from Panama City to Syracuse
Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:55 am
PTY
-
SYR
2 stops14h 26m
United Airlines
Thu 10/296:30 am
SYR
-
PTY
2 stops13h 08m
United Airlines
Deal found 1/20$571
This Faresmojo deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/152:20 pm
PTY
-
SYR
1 stop8h 39m
JetBlue
Mon 7/136:00 am
SYR
-
PTY
1 stop8h 07m
JetBlue
Deal found 1/20$657
This KAYAK deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:20 pm
PTY
-
SYR
2 stops17h 42m
Copa Airlines
Mon 7/136:07 am
SYR
-
PTY
1 stop22h 57m
Copa Airlines
Deal found 1/19$840
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:20 pm
PTY
-
SYR
2 stops24h 37m
United Airlines
Mon 7/135:33 pm
SYR
-
PTY
2 stops21h 41m
United Airlines
Deal found 1/20$889
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:10 pm
PTY
-
SYR
2 stops22h 39m
American Airlines
Mon 7/133:05 pm
SYR
-
PTY
2 stops22h 05m
American Airlines
Deal found 1/19$904

Find flight deals from Panama City to Syracuse

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$657
(Faresmojo)

One-way from

$321
(American Airlines)
Provider with most accurate pricing for Panama City Tocumen Intl-Syracuse Hancock Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Syracuse Hancock Intl flights.
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From Panama City Tocumen Intl to Syracuse Hancock Intl
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One-way flight from Panama City Tocumen Intl to Syracuse Hancock Intl
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Panama City to Syracuse that are best for you.

Fly from

Panama City

Fly to

Syracuse

Route

Depart

Return

Price

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 6/15

2:20 pm-11:59 pm

1 stop8h 39m

Syracuse Hancock Intl

Mon 7/13

6:00 am-1:07 pm

1 stop8h 07m

$657

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 6/15

3:20 pm-10:02 am

2 stops17h 42m

Syracuse Hancock Intl

Mon 7/13

6:07 am-4:04 am

1 stop22h 57m

$840

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 6/15

3:20 pm-4:57 pm

2 stops24h 37m

Syracuse Hancock Intl

Mon 7/13

5:33 pm-2:14 pm

2 stops21h 41m

$889

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 6/15

1:10 pm-12:49 pm

2 stops22h 39m

Syracuse Hancock Intl

Mon 7/13

3:05 pm-12:10 pm

2 stops22h 05m

$904

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Thu 3/19

3:10 pm-11:39 am

2 stops19h 29m

$321

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Thu 3/19

2:55 pm-11:22 am

3 stops19h 27m

$389

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Thu 3/19

9:30 am-8:18 pm

1 stop9h 48m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

  • Most accurate provider: When it comes to deals on Panama City-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Syracuse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Syracuse?

    JetBlue, Copa Airlines, and United Airlines can get you from Panama City to Syracuse in just under 8h 39m. Your travel time can differ by up to 15h 58m. Panama City and Syracuse are separated by a distance of 2359 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama City to Syracuse that include hotel bookings?

    Yes. In addition to deals on Panama City to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Syracuse.

  • Can I find deals for business class flights from Panama City to Syracuse?

    Yes. Cheapflights offers flight deals from Panama City to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Liverpool
East Syracuse
Waterloo

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Alternative routes for Panama City to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
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