$378+ Cheap flights from Panama City (PTY) to Syracuse (SYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SYR
Dec 9 — Dec 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama City to Syracuse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Syracuse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to SyracuseExplore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:55 pm -
2 stops21h 35m
Wed 12/306:00 am -
2 stops32h 45m
Deal found 11/8![United Airlines logo]()
$783
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:55 am -
2 stops25h 50m
Sun 11/152:55 pm -
2 stops29h 07m
Deal found 11/9![United Airlines logo]()
$799
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:41 pm -
1 stop9h 14m
Wed 12/307:00 pm -
2 stops18h 41m
Deal found 11/8![American Airlines logo]()
$848
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:29 pm -
1 stop8h 30m
Sun 11/156:00 am -
1 stop8h 02m
Deal found 11/9![Delta logo]()
$913
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:41 pm -
1 stop9h 14m
Sun 12/275:00 am -
1 stop8h 41m
Deal found 11/5![American Airlines logo]()
$1,162
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:55 pm -
2 stops35h 23m
Sun 11/156:45 pm -
1 stop13h 31m
Deal found 11/9![Multiple Airlines logo]()
$1,419
Best flights from Panama City to SyracuseDiscover carefully curated flight deals from Panama City to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Panama City to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/211:35 am -
2 stops23h 01m
Thu 2/186:00 am -
2 stops13h 38m
Deal found 11/8![United Airlines logo]()
$690
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/103:29 pm -
1 stop8h 30m
Wed 2/176:00 am -
1 stop7h 55m
Deal found 11/8![Delta logo]()
$957
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:41 pm -
1 stop9h 14m
Sun 12/275:00 am -
1 stop8h 41m
Deal found 11/5![American Airlines logo]()
$1,162
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/28:55 am -
2 stops25h 41m
Tue 2/97:25 pm -
2 stops24h 13m
Deal found 11/8![United Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1011:35 am -
2 stops22h 56m
Wed 2/175:35 pm -
2 stops26h 03m
Deal found 11/8![United Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/48:55 am -
2 stops25h 41m
Mon 2/87:25 pm -
2 stops21h 47m
Deal found 11/7![United Airlines logo]()
$704
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:55 pm -
2 stops21h 35m
Wed 12/306:00 am -
2 stops32h 45m
Deal found 11/8![United Airlines logo]()
$783
Last-minute flights from Panama City to SyracuseDiscover last-minute flight deals from Panama City to Syracuse. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Syracuse. Data last updated November 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:55 am -
2 stops25h 50m
Sun 11/152:55 pm -
2 stops29h 07m
Deal found 11/9![United Airlines logo]()
$799
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:29 pm -
1 stop8h 30m
Sun 11/156:00 am -
1 stop8h 02m
Deal found 11/9![Delta logo]()
$913
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:55 pm -
2 stops35h 23m
Sun 11/156:45 pm -
1 stop13h 31m
Deal found 11/9![Multiple Airlines logo]()
$1,419
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:41 pm -
1 stop9h 14m
Sun 12/275:00 am -
1 stop8h 41m
Deal found 11/5![American Airlines logo]()
$1,162
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:55 pm -
2 stops21h 35m
Wed 12/306:00 am -
2 stops32h 45m
Deal found 11/8![United Airlines logo]()
$783
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:41 pm -
1 stop9h 14m
Wed 12/307:00 pm -
2 stops18h 41m
Deal found 11/8![American Airlines logo]()
$848
One-way flights from Panama City to SyracuseSearch for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:41 pm -
2 stops21h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1711:35 am -
2 stops22h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/182:25 pm -
1 stop8h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/214:55 pm -
2 stops19h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/233:29 pm -
1 stop19h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$416
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/158:55 am -
2 stops25h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/224:55 pm -
2 stops19h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$469
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2112:03 pm -
1 stop21h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/194:24 pm -
2 stops25h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:00 am -
2 stops24h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2412:03 pm -
1 stop21h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$494
Find flight deals from Panama City to Syracuse
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $690 (United Airlines) |
One-way from | $531 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Panama City to Syracuse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Wed 1/20
4:41 pm-2:19 pm
2 stops21h 38m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$378
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Tue 2/16
4:41 pm-2:17 pm
2 stops21h 36m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$378
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Wed 2/17
11:35 am-9:50 am
2 stops22h 15m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$384
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Sat 1/23
3:29 pm-4:33 pm
2 stops25h 04m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$416
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Tue 1/19
10:00 am-10:36 am
2 stops24h 36m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$490
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Tue 2/16
9:31 pm-8:51 pm
3 stops23h 20m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$579
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Sat 1/16
8:16 am-9:11 am
3 stops24h 55m
Syracuse Hancock Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$580
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Tue 2/2
11:35 am-10:36 am
2 stops23h 01m
Syracuse Hancock Intl
Thu 2/18
6:00 am-7:38 pm
2 stops13h 38m
$690
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Tue 2/2
8:55 am-10:36 am
2 stops25h 41m
Syracuse Hancock Intl
Tue 2/9
7:25 pm-7:38 pm
2 stops24h 13m
$690
Panama CitySyracuse
PTY Panama City Tocumen Intl - SYR Syracuse Hancock Intl
PTYSYR
Panama City Tocumen Intl
Wed 2/10
11:35 am-10:31 am
2 stops22h 56m
Syracuse Hancock Intl
Wed 2/17
5:35 pm-7:38 pm
2 stops26h 03m
$690
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Panama City to Syracuse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Syracuse in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Syracuse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Syracuse
Have a flexible travel schedule? Discover the best time to fly to Syracuse from Panama City with our price prediction graph.
PTY-SYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Panama City to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Syracuse?
Book flights to Syracuse if you plan to visit one of these locationsEast Syracuse
Auburn
Liverpool
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Panama City
Popular flights
Syracuse flight routes