HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Syracuse

$661+ Cheap flights from Panama City (PTY) to Syracuse (SYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SYR
Apr 29 — May 61
Wed 4/29
Wed 5/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Syracuse with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Syracuse

Cheapest flights from Panama City to Syracuse
Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:25 am
PTY
-
SYR
2 stops29h 16m
Multiple Airlines
Sun 5/176:03 pm
SYR
-
PTY
1 stop27h 16m
Multiple Airlines
Deal found 3/26$661
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:49 pm
PTY
-
SYR
2 stops26h 34m
American Airlines
Sun 5/176:15 pm
SYR
-
PTY
2 stops19h 31m
American Airlines
Deal found 3/26$714
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm
PTY
-
SYR
2 stops24h 37m
United Airlines
Fri 10/235:33 pm
SYR
-
PTY
2 stops21h 41m
United Airlines
Deal found 3/29$804
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:03 pm
PTY
-
SYR
1 stop29h 33m
Multiple Airlines
Mon 7/208:02 pm
SYR
-
PTY
2 stops29h 33m
Multiple Airlines
Deal found 3/30$861
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:14 pm
PTY
-
SYR
2 stops20h 06m
American Airlines
Mon 7/207:24 pm
SYR
-
PTY
2 stops17h 50m
American Airlines
Deal found 3/30$875
This BusinessClass deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:24 pm
PTY
-
SYR
1 stop8h 34m
LATAM Airlines
Mon 7/206:00 am
SYR
-
PTY
1 stop8h 05m
LATAM Airlines
Deal found 3/30$1,827

Find flight deals from Panama City to Syracuse

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$661
(Kiwi.com)
Provider with most accurate pricing for Panama City Tocumen Intl-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Syracuse Hancock Intl flights.
Search Deals
From Panama City Tocumen Intl to Syracuse Hancock Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Panama City to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Sun 5/10

4:25 am-10:41 am

2 stops29h 16m

Syracuse Hancock Intl

Sun 5/17

6:03 pm-8:19 pm

1 stop27h 16m

$661

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Sun 5/10

1:49 pm-5:23 pm

2 stops26h 34m

Syracuse Hancock Intl

Sun 5/17

6:15 pm-12:46 pm

2 stops19h 31m

$714

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Wed 7/8

12:03 pm-6:36 pm

1 stop29h 33m

Syracuse Hancock Intl

Mon 7/20

8:02 pm-12:35 am

2 stops29h 33m

$861

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Wed 7/8

1:14 pm-10:20 am

2 stops20h 06m

Syracuse Hancock Intl

Mon 7/20

7:24 pm-12:14 pm

2 stops17h 50m

$875
Quickest round-trip

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Wed 7/8

2:24 pm-11:58 pm

1 stop8h 34m

Syracuse Hancock Intl

Mon 7/20

6:00 am-1:05 pm

1 stop8h 05m

$1,827

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Panama City-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Syracuse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Syracuse?

    American Airlines and LATAM Airlines can get you from Panama City to Syracuse in just under 8h 34m. Your travel time can differ by up to 18h. Panama City and Syracuse are separated by a distance of 2359 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama City to Syracuse that include hotel bookings?

    Yes. In addition to deals on Panama City to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Syracuse.

  • Can I find deals for business class flights from Panama City to Syracuse?

    Yes. Cheapflights offers flight deals from Panama City to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
East Syracuse
Liverpool
Waterloo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to John F Kennedy Intl flights
Panama City to Newark flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.