In terms of precipitation, rainfall in Syracuse ranges from 2.1 - 3.8 inches per month. July is typically the wettest month, when rainfall can reach 3.8 in. February is typically the driest time to visit Syracuse when rainfall is around 2.1 in.

If weather is an important factor for your trip to Syracuse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What is the cheapest time of day to fly from PTY to SYR?

When flying from Panama City to Syracuse, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Panama City-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Syracuse flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to Syracuse that include hotel bookings?

Yes. In addition to deals on Panama City to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Syracuse?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Syracuse.

Can I find deals for business class flights from Panama City to Syracuse?

Yes. Cheapflights offers flight deals from Panama City to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$401+ Flights from Panama City to Syracuse

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Cheap flight deals from Panama City to Syracuse

Cheapest

One-way

Cheapest flights from Panama City to Syracuse
Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

Tue 10/279:30 am

PTY

SYR

2 stops13h 03m

United Airlines

Thu 10/296:30 am

SYR

PTY

2 stops13h 08m

United Airlines

Deal found 2/1

$791

One-way flights from Panama City to Syracuse
Search for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.

Mon 3/303:51 pm

PTY

SYR

2 stops19h 50m

American Airlines

Deal found 1/31

$401

Fri 4/310:00 am

PTY

SYR

2 stops22h 55m

United Airlines

Deal found 2/1

$436

Mon 3/3010:10 am

PTY

SYR

3 stops51h 01m

Multiple Airlines

Deal found 1/31

$443

Fri 4/39:33 pm

PTY

SYR

3 stops45h 52m

Multiple Airlines

Deal found 2/1

$573

Mon 3/309:45 am

PTY

SYR

1 stop9h 35m

United Airlines

Deal found 1/31

$594

Find flight deals from Panama City to Syracuse

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars

Provider with most accurate pricing for Panama City Tocumen Intl-Syracuse Hancock Intl flight deals.

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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Syracuse Hancock Intl flights.

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Use the filters below to find and compare flights from Panama City to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 3/30

3:51 pm-12:41 pm

2 stops19h 50m

$401

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Fri 4/3

10:00 am-9:55 am

2 stops22h 55m

$436

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 3/30

10:10 am-2:11 pm

3 stops51h 01m

$443

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Fri 4/3

9:33 pm-8:25 pm

3 stops45h 52m

$573

Panama CitySyracuse

PTY - SYR

PTYSYR

Panama City Tocumen Intl

Mon 3/30

9:45 am-8:20 pm

1 stop9h 35m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/31

Most accurate provider: When it comes to deals on Panama City-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Syracuse flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Panama City with our price prediction graph.

PTY-SYR

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Can I find deals for flights from Panama City to Syracuse that include hotel bookings?
Yes. In addition to deals on Panama City to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Syracuse?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Syracuse.
Can I find deals for business class flights from Panama City to Syracuse?
Yes. Cheapflights offers flight deals from Panama City to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$401+ Cheap flights from Panama City (PTY) to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Syracuse with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Syracuse

Cheapest flights from Panama City to SyracuseExplore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

One-way flights from Panama City to SyracuseSearch for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.

Search for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.

Find flight deals from Panama City to Syracuse

Most accurate provider

Most trusted provider

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Syracuse that are best for you.

Best time to book a flight from Panama City to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Panama City with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Panama City to Syracuse that include hotel bookings?

How can I find direct flights from Panama City to Syracuse?

Can I find deals for business class flights from Panama City to Syracuse?

Traveling to a place near Syracuse?

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Alternative routes for Panama City to Syracuse

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Cheapest flights from Panama City to Syracuse
Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

One-way flights from Panama City to Syracuse
Search for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.