Syracuse

$305+ Cheap flights from Iowa to Syracuse (SYR)

DSM — SYR
Dec 10 — Dec 171
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Syracuse with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Syracuse

Cheapest flights from Iowa to Syracuse

Fri 12/41:23 pm -
1 stop9h 13m
Sat 12/55:25 pm -
1 stop6h 50m
Deal found 11/7$359
Fri 12/42:05 pm -
2 stops9h 21m
Sat 12/512:13 pm -
1 stop7h 48m
Deal found 11/7$364
Fri 12/41:23 pm -
1 stop9h 13m
Sun 12/66:00 am -
1 stop7h 30m
Deal found 11/7$369
Tue 11/245:15 am -
1 stop5h 06m
Tue 12/112:10 pm -
2 stops12h 00m
Deal found 11/8$369
Fri 12/46:09 am -
1 stop5h 44m
Sat 12/126:00 am -
1 stop6h 53m
Deal found 11/7$375
Wed 11/256:17 pm -
1 stop4h 35m
Tue 12/16:00 am -
1 stop7h 26m
Deal found 11/7$378
Wed 11/255:00 pm -
1 stop5h 40m
Tue 12/112:10 pm -
2 stops12h 00m
Deal found 11/7$399
Mon 11/233:24 pm -
1 stop5h 02m
Fri 11/276:00 am -
1 stop5h 32m
Deal found 11/8$409
Mon 11/239:31 am -
1 stop7h 27m
Fri 11/276:00 am -
2 stops8h 28m
Deal found 11/8$414
Thu 11/2610:59 am -
2 stops6h 54m
Sun 11/299:47 pm -
1 stop4h 56m
Deal found 11/8$458
Fri 11/275:00 pm -
1 stop5h 05m
Tue 12/112:10 pm -
2 stops12h 00m
Deal found 11/8$489
Wed 11/251:27 pm -
1 stop8h 26m
Sun 11/299:47 pm -
1 stop4h 57m
Deal found 11/9$533

Find flight deals from Iowa to Syracuse

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(American Airlines)

One-way from

$305
(Kiwi.com)

Popular in

April

Cheapest in

February

Average price

$497
Provider with most accurate pricing for Des Moines-Syracuse Hancock Intl flight deals.
Provider most trusted by Cheapflights users for Des Moines-Syracuse Hancock Intl flights.
From Iowa to Syracuse Hancock Intl
One-way flight from Iowa to Syracuse Hancock Intl
Highest demand for flights based on searches. 17% potential increase in price ($97 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Iowa to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Thu 11/26

8:28 pm-8:41 pm

2 stops23h 13m

Syracuse Hancock Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$351

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 5/1

1:45 pm-11:23 pm

1 stop8h 38m

Syracuse Hancock Intl

Wed 5/12

6:30 am-10:20 am

1 stop4h 50m

$359

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Fri 4/16

5:53 am-11:36 am

1 stop4h 43m

Syracuse Hancock Intl

Fri 5/14

5:12 pm-9:53 pm

1 stop5h 41m

$359

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Fri 12/4

1:23 pm-11:36 pm

1 stop9h 13m

Syracuse Hancock Intl

Sat 12/5

5:25 pm-11:15 pm

1 stop6h 50m

$359

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Fri 12/4

2:05 pm-12:26 am

2 stops9h 21m

Syracuse Hancock Intl

Sun 12/6

6:35 pm-12:33 am

1 stop6h 58m

$364

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Sat 5/1

1:45 pm-11:23 pm

1 stop8h 38m

Syracuse Hancock Intl

Sun 5/9

6:30 am-12:22 pm

1 stop6h 52m

$369

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Fri 12/4

6:09 am-12:53 pm

1 stop5h 44m

Syracuse Hancock Intl

Sat 12/12

6:00 am-11:53 am

1 stop6h 53m

$375

Cedar RapidsSyracuse

CID Cedar Rapids - SYR Syracuse Hancock Intl

CIDSYR

Cedar Rapids

Wed 1/20

5:00 am-10:36 am

1 stop4h 36m

Syracuse Hancock Intl

Sat 1/23

5:24 pm-9:58 pm

1 stop5h 34m

$401

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Wed 11/25

8:00 am-6:53 pm

2 stops9h 53m

Syracuse Hancock Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$404

Des MoinesSyracuse

DSM Des Moines - SYR Syracuse Hancock Intl

DSMSYR

Des Moines

Fri 11/27

8:00 am-6:53 pm

2 stops9h 53m

Syracuse Hancock Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$404

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Iowa to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Iowa with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Iowa to Syracuse

What is the cheapest month to book a flight from Iowa to Syracuse?

Currently, February is the cheapest month in which you can book a flight from Iowa to Syracuse (average of $353). Flying from Iowa to Syracuse in September is currently the most expensive (average of $801). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • What airport do you fly into for flights to Syracuse from Iowa?

    Most people fly into Syracuse Hancock Intl (SYR) if they book a flight to Syracuse from Iowa. Hancock Intl is conveniently located just 4.8 mi from Syracuse’s city center.

  • How long is the flight from Iowa to Syracuse?

    A quick flight from Iowa to Syracuse can take about 4h 43m. American Airlines provides one of the quickest options available for as low as $359. Iowa and Syracuse are separated by a distance of 901 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Syracuse?

  • Can I find deals for flights from Iowa to Syracuse that include hotel bookings?

    Yes. In addition to deals on Iowa to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Syracuse.

  • Can I find deals for business class flights from Iowa to Syracuse?

    Yes. Cheapflights offers flight deals from Iowa to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Syracuse?

    Currently, February is the cheapest month in which you can book a flight from Iowa to Syracuse (average of $353). Flying from Iowa to Syracuse in September is currently the most expensive (average of $801). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
East Syracuse
Auburn
Liverpool

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Iowa to Syracuse

Top 3 airlines flying from Iowa to Syracuse

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$326Average$436FlexibilityNo cancel feeOn-time69%
DeltaCheapest$328Average$391FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.