HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Syracuse

$172+ Cheap flights from Iowa to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SYR
Nov 16 — Nov 231
Sun 11/16
Sun 11/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Syracuse with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Syracuse

Keep the following information in mind while searching for Iowa to Syracuse flight deals. Data was last updated October 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(American Airlines)

One-way from

$172
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$287
Provider with most accurate pricing for Des Moines-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Syracuse Hancock Intl flights.
Search Deals
From Iowa to Syracuse Hancock Intl
Search Deals
One-way flight from Iowa to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Iowa to Syracuse

Cheapest flights from Iowa to Syracuse
Explore the most affordable flight options available from Iowa to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2025.

This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:17 amMLI - SYR
1 stop4h 46mAmerican Airlines
Mon 11/38:06 pmSYR - MLI
1 stop4h 15mAmerican Airlines
Deal found 10/15$259
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:32 pmDSM - SYR
1 stop4h 52mDelta
Sun 11/96:00 amSYR - DSM
1 stop4h 41mDelta
Deal found 10/16$259
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:24 amCID - SYR
1 stop4h 39mAmerican Airlines
Mon 11/36:12 pmSYR - CID
1 stop5h 53mAmerican Airlines
Deal found 10/14$259
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/291:00 pmMLI - SYR
2 stops9h 13mUnited Airlines
Sun 11/25:15 amSYR - MLI
1 stop5h 00mUnited Airlines
Deal found 10/14$264
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:02 pmDSM - SYR
1 stop5h 54mAmerican Airlines
Tue 11/182:41 pmSYR - DSM
2 stops8h 27mAmerican Airlines
Deal found 10/16$264
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:30 amCID - SYR
1 stop7h 11mAmerican Airlines
Thu 1/15:59 amSYR - CID
1 stop4h 48mAmerican Airlines
Deal found 10/14$274
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:08 pmMLI - SYR
1 stop5h 38mDelta
Wed 12/175:30 amSYR - MLI
2 stops11h 53mDelta
Deal found 10/14$279
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/301:00 pmMLI - SYR
2 stops9h 13mUnited Airlines
Mon 11/36:15 amSYR - MLI
1 stop5h 00mUnited Airlines
Deal found 10/15$284
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:00 amOMA - SYR
1 stop7h 03mAmerican Airlines
Mon 11/35:47 pmSYR - OMA
1 stop7h 12mAmerican Airlines
Deal found 10/15$289
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:15 pmDSM - SYR
1 stop6h 51mDelta
Mon 11/36:00 amSYR - DSM
1 stop8h 28mDelta
Deal found 10/15$289
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:27 pmMLI - SYR
1 stop5h 04mAmerican Airlines
Wed 12/173:57 pmSYR - MLI
1 stop7h 50mAmerican Airlines
Deal found 10/14$304
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amMLI - SYR
1 stop3h 57mAmerican Airlines
Tue 10/217:40 amSYR - MLI
1 stop4h 12mAmerican Airlines
Deal found 10/14$324

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 17, 2025.
Use the filters below to find and compare flights from Iowa to Syracuse that are best for you.

Fly from

Iowa

Fly to

Syracuse

Route

Depart

Return

Price

MolineSyracuse

MLI - SYR

MLISYR

Moline Quad-City

Thu 10/30

8:17 am-2:03 pm

1 stop4h 46m

Syracuse Hancock Intl

Mon 11/3

8:06 pm-11:21 pm

1 stop4h 15m

$259

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Fri 11/7

3:15 pm-9:02 pm

1 stop4h 47m

Syracuse Hancock Intl

Sun 11/9

6:15 am-10:30 am

1 stop5h 15m

$259

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Fri 11/7

5:56 pm-11:04 pm

1 stop4h 08m

Syracuse Hancock Intl

Sun 11/9

6:00 am-9:41 am

1 stop4h 41m

$259

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 11/15

6:17 am-12:08 pm

1 stop4h 51m

Syracuse Hancock Intl

Tue 11/18

12:56 pm-4:19 pm

1 stop4h 23m

$259

Cedar RapidsSyracuse

CID - SYR

CIDSYR

Cedar Rapids

Thu 10/30

8:24 am-2:03 pm

1 stop4h 39m

Syracuse Hancock Intl

Mon 11/3

6:12 pm-11:05 pm

1 stop5h 53m

$259

MolineSyracuse

MLI - SYR

MLISYR

Moline Quad-City

Wed 10/29

1:00 pm-11:13 pm

2 stops9h 13m

Syracuse Hancock Intl

Sun 11/2

5:15 am-9:15 am

1 stop5h 00m

$264

Des MoinesSyracuse

DSM - SYR

DSMSYR

Des Moines

Sat 11/15

4:02 pm-10:56 pm

1 stop5h 54m

Syracuse Hancock Intl

Tue 11/18

2:41 pm-10:08 pm

2 stops8h 27m

$264

Cedar RapidsSyracuse

CID - SYR

CIDSYR

Cedar Rapids

Thu 12/25

8:30 am-4:41 pm

1 stop7h 11m

Syracuse Hancock Intl

Thu 1/1

5:59 am-9:47 am

1 stop4h 48m

$274

MolineSyracuse

MLI - SYR

MLISYR

Moline Quad-City

Thu 10/30

1:00 pm-11:13 pm

2 stops9h 13m

Syracuse Hancock Intl

Mon 11/3

6:15 am-10:15 am

1 stop5h 00m

$284

MolineSyracuse

MLI - SYR

MLISYR

Moline Quad-City

Wed 12/3

6:00 am-4:53 pm

2 stops9h 53m

Syracuse Hancock Intl

Wed 12/17

5:30 am-4:23 pm

2 stops11h 53m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 30 results
1
2
3

Best time to book a flight from Iowa to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Syracuse

What is the cheapest month to book a flight from Iowa to Syracuse?

Currently, May is the cheapest month in which you can book a flight from Iowa to Syracuse (average of $159). Flying from Iowa to Syracuse in March is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Syracuse from Iowa?

    Most people fly into Syracuse Hancock Intl (SYR) if they book a flight to Syracuse from Iowa. Hancock Intl is conveniently located just 4.8 mi from Syracuse’s city center.

  • How long is the flight from Iowa to Syracuse?

    A quick flight from Iowa to Syracuse can take about 4h 08m. American Airlines provides one of the quickest options available for as low as $259. Iowa and Syracuse are separated by a distance of 901 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Iowa to Syracuse one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $172. Users have also found prices from $239 and $271 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Iowa to Syracuse?

    The most popular flight routes from Iowa to Syracuse are Cedar Rapids - Syracuse Hancock Intl, Des Moines - Syracuse Hancock Intl and Omaha Eppley Airfield - Syracuse Hancock Intl.

  • Can I find deals for flights from Iowa to Syracuse that include hotel bookings?

    Yes. In addition to deals on Iowa to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Syracuse.

  • Can I find deals for business class flights from Iowa to Syracuse?

    Yes. Cheapflights offers flight deals from Iowa to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Syracuse?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Syracuse (average of $159). Flying from Iowa to Syracuse in March is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Cicero
Liverpool
East Syracuse
Waterloo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
Los Angeles to Newark flights
San Francisco to John F Kennedy Intl flights
O'Hare Intl to John F Kennedy Intl flights
San Francisco to Newark flights
Dallas/Fort Worth to Newark flights
Los Angeles to LaGuardia flights
Orlando to John F Kennedy Intl flights
Atlanta to LaGuardia flights
O'Hare Intl to Newark flights
O'Hare Intl to LaGuardia flights
Atlanta to John F Kennedy Intl flights
Hobby to LaGuardia flights
Hobby to John F Kennedy Intl flights
Seattle to John F Kennedy Intl flights
Hobby to Newark flights
Miami to John F Kennedy Intl flights
Tampa to John F Kennedy Intl flights
Fort Lauderdale to LaGuardia flights
San Francisco to LaGuardia flights
Fort Lauderdale to John F Kennedy Intl flights
Atlanta to Newark flights
Fort Lauderdale to Newark flights
George Bush Intcntl to John F Kennedy Intl flights
George Bush Intcntl to Newark flights
Denver to John F Kennedy Intl flights
Austin to John F Kennedy Intl flights
Tampa to LaGuardia flights
Miami to Newark flights
Raleigh to John F Kennedy Intl flights
Orlando to LaGuardia flights
Tampa to Newark flights
Denver to LaGuardia flights
George Bush Intcntl to LaGuardia flights
Raleigh to LaGuardia flights
Minneapolis to John F Kennedy Intl flights
Denver to Newark flights
Seattle to Newark flights
Charlotte to John F Kennedy Intl flights
Sky Harbor Intl to John F Kennedy Intl flights
San Diego to John F Kennedy Intl flights
Miami to LaGuardia flights
Austin to Newark flights
Minneapolis to LaGuardia flights
Orlando to Newark flights
Minneapolis to Newark flights
Boston to LaGuardia flights
Indianapolis to John F Kennedy Intl flights

Top 2 airlines flying from Iowa to Syracuse

Discover the top 2 airlines that operate flights from Iowa to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$328FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$362FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.