HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$73+ Cheap flights from Spartanburg, SC to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — STL
dic. 26 — ene. 21
vie. 12/26
vie. 1/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Spartanburg to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Spartanburg to Lambert-St Louis are usually found in August or October, booked 57 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to St. Louis

Keep the following information in mind while searching for Spartanburg to St. Louis flight deals. Data was last updated noviembre 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$156
(Kiwi.com)

One-way from

$73
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$335
Provider with most accurate pricing for Charlotte Douglas-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Lambert-St Louis flights.
Search Deals
From Spartanburg to Lambert-St Louis
Search Deals
One-way flight from Spartanburg to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Spartanburg to St. Louis

Cheapest flights from Spartanburg to St. Louis
Explore the most affordable flight options available from Spartanburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 26, 2025.

This Expedia deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1110:33 pmCLT - STL
1 stop11h 26mFrontier
lun. 12/159:54 amSTL - CLT
1 stop9h 31mFrontier
Deal found 11/26$162
This Priceline deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/192:51 pmCLT - STL
1 stop5h 51mFrontier
lun. 12/229:07 amSTL - CLT
1 stop6h 54mFrontier
Deal found 11/24$187
This Expedia deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/289:33 pmCLT - STL
1 stop13h 12mMultiple Airlines
jue. 1/111:51 amSTL - CLT
1 stop7h 42mMultiple Airlines
Deal found 11/24$199
This Southwest deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2512:55 pmCLT - STL
Nonstop2h 10mSouthwest
jue. 1/12:55 pmSTL - CLT
Nonstop1h 45mSouthwest
Deal found 11/25$217
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/264:23 pmCLT - STL
Nonstop2h 01mAmerican Airlines
mar. 1/66:52 amSTL - CLT
Nonstop1h 50mAmerican Airlines
Deal found 11/26$240
This Southwest deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/265:45 amCLT - STL
1 stop4h 25mSouthwest
mar. 12/305:05 pmSTL - CLT
Nonstop1h 45mSouthwest
Deal found 11/23$250
This Kiwi.com deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/111:57 pmCLT - STL
2 stops20h 50mMultiple Airlines
lun. 12/159:54 amSTL - CLT
1 stop9h 06mMultiple Airlines
Deal found 11/26$251
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2712:16 pmCLT - STL
Nonstop2h 01mAmerican Airlines
sáb. 11/299:12 amSTL - CLT
Nonstop1h 54mAmerican Airlines
Deal found 11/23$252
This Expedia deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/192:51 pmCLT - STL
1 stop5h 51mMultiple Airlines
dom. 12/2111:51 amSTL - CLT
1 stop7h 42mMultiple Airlines
Deal found 11/23$258

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
Use the filters below to find and compare flights from Spartanburg to St. Louis that are best for you.

Fly from

Spartanburg

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

jue. 1/22

6:01 pm-11:33 pm

1 stop6h 32m

Lambert-St Louis

mar. 1/27

5:42 pm-10:40 am

1 stop15h 58m

$177

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

dom. 12/28

9:33 pm-9:45 am

1 stop13h 12m

Lambert-St Louis

jue. 1/1

11:51 am-8:33 pm

1 stop7h 42m

$199

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

jue. 12/25

12:55 pm-2:05 pm

Nonstop2h 10m

Lambert-St Louis

jue. 1/1

2:55 pm-5:40 pm

Nonstop1h 45m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

jue. 1/22

8:25 am-9:35 am

Nonstop2h 10m

Lambert-St Louis

mar. 1/27

2:30 pm-5:15 pm

Nonstop1h 45m

$228

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

sáb. 1/17

11:35 am-4:53 pm

1 stop6h 18m

Lambert-St Louis

lun. 1/19

3:45 pm-9:35 pm

1 stop4h 50m

$248

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

dom. 12/28

9:25 pm-12:05 am

1 stop3h 40m

Lambert-St Louis

jue. 1/1

2:55 pm-5:40 pm

Nonstop1h 45m

$250

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

mié. 12/31

6:20 pm-10:00 pm

1 stop4h 40m

Lambert-St Louis

dom. 1/4

5:05 pm-7:50 pm

Nonstop1h 45m

$250

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

vie. 1/9

8:25 am-9:35 am

Nonstop2h 10m

Lambert-St Louis

lun. 1/12

2:30 pm-5:15 pm

Nonstop1h 45m

$251

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

sáb. 1/10

1:59 pm-3:04 pm

Nonstop2h 05m

Lambert-St Louis

sáb. 1/17

3:54 pm-6:44 pm

Nonstop1h 50m

$254

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

dom. 1/25

5:13 pm-12:50 pm

1 stop20h 37m

$75

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Showing 1-10 of 19 results
1
2

Best time to book a flight from Spartanburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to St. Louis

How far ahead should I book a flight from Spartanburg to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to St. Louis. Price data was last updated on November 21, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to St. Louis, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to St. Louis?

Currently, June is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $108). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to STL?

Find hourly flight availability from Spartanburg to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 26, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 22% on flights from Spartanburg to St. Louis by exploring options for tickets at noon.

What is the cheapest day to fly from Spartanburg to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated noviembre 26, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Spartanburg to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,254 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,038 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,099 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Spartanburg?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Spartanburg to St. Louis. 4 airlines have flights to Lambert-St Louis from Spartanburg on a regular basis. Booking flights from Spartanburg to Lambert-St Louis should not be difficult; the airport handles an average of 4 inbound flights from Spartanburg per day.

  • How popular is this Spartanburg to St. Louis flight route?

    This flight path from Spartanburg to Lambert-St Louis was viewed by 20 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to St. Louis?

    Airlines like Southwest fly from Spartanburg to St. Louis in about 2h 10m. The time it takes to get you to your destination is usually consistent. Spartanburg and St. Louis are separated by a distance of 574 mi. Most flights are nonstop.

  • What are the most reliable airlines from Spartanburg to St. Louis?

    No one likes to see their flight delayed. When booking a flight from Spartanburg to St. Louis consider choosing British Airways (86%), American Airlines (85%) or Southwest (82%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Spartanburg to St. Louis?

    Looking for the cheapest flight from Spartanburg to St. Louis? While on average our users pay $390, our data indicates the cheapest price to be $145. The most popular route (Charlotte Douglas - Lambert-St Louis), is priced around $156.

  • Can I find deals for flights from Spartanburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Spartanburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to St. Louis.

  • Can I find deals for business class flights from Spartanburg to St. Louis?

    Yes. Cheapflights offers flight deals from Spartanburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to St. Louis?

    Currently, June is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $108). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Spartanburg to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to St. Louis flights
Charlotte to Kansas City flights
Columbia to Kansas City flights
Charlotte to Springfield flights
Columbia to St. Louis flights
Charleston to Kansas City flights
Charleston to St. Louis flights
Greenville to Kansas City flights
Greenville to St. Louis flights
Savannah to St. Louis flights
Myrtle Beach to Springfield flights
Myrtle Beach to St. Louis flights
Greenville to Springfield flights
Charleston to Springfield flights
Savannah to Kansas City flights
Columbia to Springfield flights
Savannah to Springfield flights
Augusta to St. Louis flights
Charlotte to Columbia flights
Myrtle Beach to Kansas City flights
Charleston to Columbia flights
Hilton Head Island to St. Louis flights
Charlotte to Fort Leonard Wood flights
Charlotte to Joplin flights
Augusta to Kansas City flights
Myrtle Beach to Joplin flights
Columbia to Columbia flights
Florence to St. Louis flights
Florence to Kansas City flights
Hilton Head Island to Kansas City flights
Augusta to Columbia flights

Top 4 airlines flying from Spartanburg to St. Louis

Discover the top 4 airlines that operate flights from Spartanburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$148Average$212FlexibilityNo cancel feeOn-time62%
DeltaCheapest$173Average$334FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$339FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$217Average$395FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.