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St. Louis

$73+ Cheap flights from Spartanburg, SC to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — STL
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Lambert-St Louis are usually found in August or September, booked 40 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to St. Louis

Keep the following information in mind while searching for Spartanburg to St. Louis flight deals. Data was last updated August 20, 2025.

Round-trip from

$222
(FlightHub)

One-way from

$73
(Priceline)

Popular in

March

Cheapest in

August

Average price

$281
From Spartanburg to Lambert-St Louis
Search Deals
One-way flight from Spartanburg to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Spartanburg to St. Louis

Cheapest flights from Spartanburg to St. Louis
Explore the most affordable flight options available from Spartanburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:51 pmCLT - STL
1 stop17h 11mFrontier
Sun 9/2110:39 amSTL - CLT
1 stop23h 13mFrontier
Deal found 8/18$222
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:09 pmCLT - STL
1 stop19h 53mMultiple Airlines
Fri 10/314:29 pmSTL - CLT
2 stops19h 01mMultiple Airlines
Deal found 8/19$223
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:25 pmCLT - STL
Nonstop2h 05mSouthwest
Sun 10/54:20 pmSTL - CLT
Nonstop1h 50mSouthwest
Deal found 8/18$224
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/229:42 amCLT - STL
1 stop5h 39mFrontier
Sun 8/242:02 pmSTL - CLT
1 stop5h 44mFrontier
Deal found 8/18$226
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:50 pmCLT - STL
Nonstop2h 00mSouthwest
Mon 9/226:30 amSTL - CLT
1 stop5h 50mSouthwest
Deal found 8/18$227
This Frontier deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/259:42 amCLT - STL
1 stop5h 39mFrontier
Thu 9/44:00 pmSTL - CLT
2 stops16h 15mFrontier
Deal found 8/19$230
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:10 pmCLT - STL
1 stop6h 15mSouthwest
Wed 9/248:15 amSTL - CLT
2 stops7h 20mSouthwest
Deal found 8/18$232
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/34:48 pmCLT - STL
1 stop17h 52mMultiple Airlines
Sun 9/710:39 amSTL - CLT
1 stop23h 13mMultiple Airlines
Deal found 8/19$236
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1612:10 pmCLT - STL
1 stop7h 12mAmerican Airlines
Sat 9/206:29 amSTL - CLT
Nonstop1h 58mAmerican Airlines
Deal found 8/19$237
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:50 pmCLT - STL
Nonstop2h 00mSouthwest
Wed 10/16:25 amSTL - CLT
1 stop9h 10mSouthwest
Deal found 8/18$239
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:05 pmCLT - STL
Nonstop2h 02mAmerican Airlines
Sun 10/56:00 amSTL - CLT
1 stop5h 17mAmerican Airlines
Deal found 8/18$240

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Spartanburg to St. Louis that are best for you.

Fly from

Spartanburg

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 9/18

8:51 pm-1:02 pm

1 stop17h 11m

Lambert-St Louis

Sun 9/21

10:39 am-10:52 am

1 stop23h 13m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 10/10

12:05 pm-5:10 pm

1 stop6h 05m

Lambert-St Louis

Sun 10/12

10:57 am-9:00 pm

1 stop9h 03m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 9/17

4:50 pm-9:25 pm

1 stop5h 35m

Lambert-St Louis

Wed 9/24

8:15 am-4:35 pm

2 stops7h 20m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 9/22

7:50 pm-8:50 pm

Nonstop2h 00m

Lambert-St Louis

Wed 9/24

6:25 am-4:35 pm

1 stop9h 10m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 9/11

1:11 pm-9:06 am

2 stops20h 55m

Lambert-St Louis

Sun 9/14

10:39 am-7:55 am

2 stops20h 16m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 9/29

7:50 pm-8:50 pm

Nonstop2h 00m

Lambert-St Louis

Wed 10/1

6:25 am-4:35 pm

1 stop9h 10m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 10/27

3:09 pm-10:02 am

1 stop19h 53m

Lambert-St Louis

Fri 10/31

4:29 pm-12:30 pm

2 stops19h 01m

$223

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/1

5:25 pm-6:30 pm

Nonstop2h 05m

Lambert-St Louis

Sun 10/5

4:20 pm-7:10 pm

Nonstop1h 50m

$224

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sun 8/31

6:00 am-1:07 pm

1 stop8h 07m

Lambert-St Louis

Fri 9/5

1:57 pm-1:01 pm

1 stop22h 04m

$226

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 9/15

7:50 pm-8:50 pm

Nonstop2h 00m

Lambert-St Louis

Mon 9/22

6:30 am-1:20 pm

1 stop5h 50m

$227

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 20 results
1
2

Best time to book a flight from Spartanburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to St. Louis

How far ahead should I book a flight from Spartanburg to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to St. Louis. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to St. Louis, you should look to book at least 40 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $311). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to STL?

Find hourly flight availability from Spartanburg to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

When flying from Spartanburg to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Spartanburg to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to St. Louis flight should consider departing on Saturday at noon when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 20, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Spartanburg to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,207 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Spartanburg?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Spartanburg to St. Louis. 4 airlines have flights to Lambert-St Louis from Spartanburg on a regular basis. Booking flights from Spartanburg to Lambert-St Louis should not be difficult; the airport handles an average of 3 inbound flights from Spartanburg per day.

  • How popular is this Spartanburg to St. Louis flight route?

    This flight path from Spartanburg to Lambert-St Louis was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to St. Louis?

    Airlines like Frontier and Southwest fly from Spartanburg to St. Louis in about 5h 35m. The time it takes to get you to your destination can typically vary by up to 11h 36m. Spartanburg and St. Louis are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Spartanburg to St. Louis?

    No one likes to see their flight delayed. When booking a flight from Spartanburg to St. Louis consider choosing PSA Airlines (86%), Southwest (73%) or American Airlines (66%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Spartanburg to St. Louis?

    Looking for the cheapest flight from Spartanburg to St. Louis? While on average our users pay $253, our data indicates the cheapest price to be $118. The most popular route (Charlotte Douglas - Lambert-St Louis), is priced around $192.

  • Can I find deals for flights from Spartanburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Spartanburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to St. Louis.

  • Can I find deals for business class flights from Spartanburg to St. Louis?

    Yes. Cheapflights offers flight deals from Spartanburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $311). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Farmington
Festus

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Top 4 airlines flying from Spartanburg to St. Louis

Discover the top 4 airlines that operate flights from Spartanburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$132Average$205FlexibilityNo cancel feeOn-time62%
DeltaCheapest$192Average$330FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$348FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$221Average$349FlexibilityNo cancel feeOn-time63%

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