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St. Louis

$64+ Cheap flights from Spartanburg, SC to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — STL
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Spartanburg to Lambert-St Louis are usually found in January or August, booked 57 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to St. Louis

Cheapest flights from Spartanburg to St. Louis
Explore the most affordable flight options available from Spartanburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:26 pmCLT - STL
Nonstop2h 04mAmerican Airlines
Sat 1/108:13 amSTL - CLT
Nonstop1h 58mAmerican Airlines
Deal found 12/26$252
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:15 pmCLT - STL
1 stop5h 13mDelta
Sat 1/35:55 amSTL - CLT
1 stop3h 58mDelta
Deal found 12/27$272
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:15 pmCLT - STL
Nonstop1h 59mAmerican Airlines
Fri 1/27:05 amSTL - CLT
Nonstop2h 02mAmerican Airlines
Deal found 12/27$276
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:02 amCLT - STL
1 stop7h 52mUnited Airlines
Sat 1/109:57 amSTL - CLT
2 stops8h 00mUnited Airlines
Deal found 12/26$277
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:15 amCLT - STL
1 stop5h 06mDelta
Fri 1/26:29 amSTL - CLT
1 stop4h 56mDelta
Deal found 12/27$296
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:02 amCLT - STL
1 stop6h 25mUnited Airlines
Fri 1/23:10 pmSTL - CLT
2 stops7h 49mUnited Airlines
Deal found 12/27$301
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:23 pmCLT - STL
Nonstop2h 01mAmerican Airlines
Fri 1/25:00 amSTL - CLT
Nonstop1h 59mAmerican Airlines
Deal found 12/27$311
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:05 pmCLT - STL
1 stop4h 56mDelta
Fri 1/26:00 amSTL - CLT
1 stop3h 53mDelta
Deal found 12/27$331
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:55 pmCLT - STL
Nonstop2h 00mAmerican Airlines
Sun 1/113:54 pmSTL - CLT
Nonstop1h 50mAmerican Airlines
Deal found 12/26$335

Find flight deals from Spartanburg to St. Louis

Keep the following information in mind while searching for Spartanburg to St. Louis flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$145
(Expedia)

One-way from

$64
(Frontier)

Popular in

March

Cheapest in

January

Average price

$299
Provider with most accurate pricing for Charlotte Douglas-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Lambert-St Louis flights.
Search Deals
From Spartanburg to Lambert-St Louis
Search Deals
One-way flight from Spartanburg to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Spartanburg to St. Louis that are best for you.

Fly from

Spartanburg

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 1/21

6:01 pm-11:33 pm

1 stop6h 32m

Lambert-St Louis

Wed 1/28

5:42 pm-4:54 pm

1 stop22h 12m

$132

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 1/17

7:00 am-9:45 am

1 stop3h 45m

Lambert-St Louis

Sun 1/18

2:30 pm-5:15 pm

Nonstop1h 45m

$209

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 2/10

2:46 pm-10:27 pm

1 stop8h 41m

Lambert-St Louis

Fri 2/13

1:59 pm-5:48 pm

2 stops26h 49m

$218

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 1/21

8:25 am-9:35 am

Nonstop2h 10m

Lambert-St Louis

Wed 1/28

2:30 pm-5:15 pm

Nonstop1h 45m

$225

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 1/28

6:10 am-11:02 am

1 stop5h 52m

Lambert-St Louis

Sat 1/31

1:15 pm-9:37 pm

1 stop7h 22m

$237

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 1/28

5:50 pm-9:00 pm

1 stop4h 10m

Lambert-St Louis

Sat 1/31

1:45 pm-7:15 pm

1 stop4h 30m

$237

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 1/31

7:00 am-9:45 am

1 stop3h 45m

Lambert-St Louis

Mon 2/2

2:30 pm-5:15 pm

Nonstop1h 45m

$243

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 2/10

8:25 am-9:35 am

Nonstop2h 10m

Lambert-St Louis

Fri 2/13

3:00 pm-9:25 pm

1 stop5h 25m

$250

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 1/1

7:24 am-8:35 am

Nonstop2h 11m

Lambert-St Louis

Sat 1/3

7:05 am-10:07 am

Nonstop2h 02m

$252

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 12/31

6:26 pm-7:30 pm

Nonstop2h 04m

Lambert-St Louis

Sat 1/3

9:09 am-12:15 pm

Nonstop2h 06m

$252

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 19 results
1
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Best time to book a flight from Spartanburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to St. Louis

How far ahead should I book a flight from Spartanburg to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to St. Louis. Price data was last updated on December 26, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to St. Louis, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to St. Louis?

Currently, June is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $108). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to STL?

Find hourly flight availability from Spartanburg to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 37% on flights from Spartanburg to St. Louis by exploring options for tickets at noon.

What is the cheapest day to fly from Spartanburg to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to St. Louis. Price data was last updated on December 27, 2025.

Travelers seeking maximum savings on their Spartanburg to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Spartanburg to St. Louis

Explore weekly flight availability from Spartanburg to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 28, 2025.

The most flights from SB1 to STL are scheduled on a Monday (9 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 28, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Spartanburg to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,256 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,256 reviews
Southwest
8.0
Very good
4,256 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,019 reviews
Southwest
8.0
Very good
4,256 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,073 reviews
Southwest
8.0
Very good
4,256 reviews

Crew

8.6

Overall

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Spartanburg?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Spartanburg to St. Louis. 4 airlines have flights to Lambert-St Louis from Spartanburg on a regular basis. Booking flights from Spartanburg to Lambert-St Louis should not be difficult; the airport handles an average of 8 inbound flights from Spartanburg per day.

  • How popular is this Spartanburg to St. Louis flight route?

    This flight path from Spartanburg to Lambert-St Louis was viewed by 21 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to St. Louis?

    Airlines like Southwest and Frontier fly from Spartanburg to St. Louis in about 3h 45m. The time it takes to get you to your destination can typically vary by up to 4h 56m. Spartanburg and St. Louis are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Spartanburg to St. Louis one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $62. Users have also found prices from $108 and $125 on Delta and Southwest, respectively.

  • What are the most reliable airlines from Spartanburg to St. Louis?

    No one likes to see their flight delayed. When booking a flight from Spartanburg to St. Louis consider choosing PSA Airlines (83%), American Airlines (80%) or Southwest (79%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Spartanburg to St. Louis?

    Looking for the cheapest flight from Spartanburg to St. Louis? While on average our users pay $294, our data indicates the cheapest price to be $152. The most popular route (Charlotte Douglas - Lambert-St Louis), is priced around $151.

  • Can I find deals for flights from Spartanburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Spartanburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to St. Louis.

  • Can I find deals for business class flights from Spartanburg to St. Louis?

    Yes. Cheapflights offers flight deals from Spartanburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to St. Louis?

    Currently, June is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $108). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Spartanburg to St. Louis

Discover the top 4 airlines that operate flights from Spartanburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$133Average$205FlexibilityNo cancel feeOn-time62%
DeltaCheapest$149Average$323FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$337FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$217Average$320FlexibilityNo cancel feeOn-time63%

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