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St. Louis

$72+ Cheap flights from Spartanburg, SC to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — STL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Lambert-St Louis are usually found in August or September, booked 74 days in advance, depart on a Thursday or Saturday and return on a Wednesday

Cheap flight deals from Spartanburg to St. Louis

Keep the following information in mind while searching for Spartanburg to St. Louis flight deals. Data was last updated September 16, 2025.

Round-trip from

$217
(United Airlines)

One-way from

$72
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$303
From Spartanburg to Lambert-St Louis
Search Deals
One-way flight from Spartanburg to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Spartanburg to St. Louis

Cheapest flights from Spartanburg to St. Louis
Explore the most affordable flight options available from Spartanburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:30 amCLT - STL
1 stop5h 19mUnited Airlines
Wed 10/223:23 pmSTL - CLT
1 stop5h 18mUnited Airlines
Deal found 9/15$217
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:05 amCLT - STL
1 stop5h 40mSouthwest
Wed 10/2210:05 amSTL - CLT
2 stops6h 30mSouthwest
Deal found 9/15$222
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1110:19 amCLT - STL
1 stop8h 51mMultiple Airlines
Tue 10/147:52 pmSTL - CLT
2 stops37h 03mMultiple Airlines
Deal found 9/15$226
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:00 amCLT - STL
2 stops9h 10mSouthwest
Tue 10/2110:05 amSTL - CLT
2 stops9h 25mSouthwest
Deal found 9/16$227
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:01 pmCLT - STL
2 stops20h 05mFrontier
Mon 10/69:32 pmSTL - CLT
2 stops15h 18mFrontier
Deal found 9/14$230
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:20 pmCLT - STL
1 stop5h 00mSouthwest
Tue 10/146:40 pmSTL - CLT
Nonstop1h 50mSouthwest
Deal found 9/15$231
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:20 pmCLT - STL
1 stop6h 45mSouthwest
Mon 10/272:05 pmSTL - CLT
2 stops8h 15mSouthwest
Deal found 9/15$232
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:01 pmCLT - STL
2 stops20h 05mFrontier
Sun 10/510:39 amSTL - CLT
2 stops20h 16mFrontier
Deal found 9/13$233
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:20 pmCLT - STL
1 stop16h 46mFrontier
Thu 10/27:55 pmSTL - CLT
1 stop19h 48mFrontier
Deal found 9/15$236
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:30 amCLT - STL
1 stop3h 46mDelta
Thu 11/276:40 amSTL - CLT
1 stop7h 10mDelta
Deal found 9/15$237
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1410:00 pmCLT - STL
Nonstop2h 05mAmerican Airlines
Sat 10/186:00 amSTL - CLT
1 stop4h 21mAmerican Airlines
Deal found 9/14$238
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:23 amCLT - STL
Nonstop2h 04mAmerican Airlines
Thu 11/277:11 amSTL - CLT
Nonstop1h 58mAmerican Airlines
Deal found 9/14$240

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Spartanburg to St. Louis that are best for you.

Fly from

Spartanburg

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/22

7:05 am-11:45 am

1 stop5h 40m

Lambert-St Louis

Wed 10/22

6:40 pm-9:30 pm

Nonstop1h 50m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 10/11

5:25 pm-8:33 pm

1 stop4h 08m

Lambert-St Louis

Tue 10/14

9:10 am-4:40 pm

1 stop6h 30m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 10/30

3:50 pm-4:50 pm

Nonstop2h 00m

Lambert-St Louis

Mon 11/3

2:55 pm-5:40 pm

Nonstop1h 45m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 10/14

9:39 am-12:35 pm

1 stop3h 56m

Lambert-St Louis

Sat 10/18

10:45 am-3:55 pm

1 stop4h 10m

$227

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 10/21

7:05 am-2:10 pm

2 stops8h 05m

Lambert-St Louis

Wed 10/22

10:05 am-5:35 pm

2 stops6h 30m

$227

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 10/11

4:20 pm-8:20 pm

1 stop5h 00m

Lambert-St Louis

Tue 10/14

6:40 pm-9:30 pm

Nonstop1h 50m

$231

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/15

4:20 pm-10:05 pm

1 stop6h 45m

Lambert-St Louis

Mon 10/27

2:05 pm-11:20 pm

2 stops8h 15m

$232

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 12/4

6:00 am-12:15 pm

2 stops7h 15m

Lambert-St Louis

Sat 12/6

3:13 pm-11:59 pm

2 stops7h 46m

$237

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 11/25

5:30 am-8:16 am

1 stop3h 46m

Lambert-St Louis

Thu 11/27

6:40 am-2:50 pm

1 stop7h 10m

$237

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 11/19

5:10 pm-10:10 pm

1 stop6h 00m

Lambert-St Louis

Sun 11/23

4:15 pm-7:00 pm

Nonstop1h 45m

$240

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 18 results
1
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Best time to book a flight from Spartanburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to St. Louis

How far ahead should I book a flight from Spartanburg to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to St. Louis. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to St. Louis, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $311). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to STL?

Find hourly flight availability from Spartanburg to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Spartanburg to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Spartanburg to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to St. Louis flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Spartanburg to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,957 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,174 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Spartanburg?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Spartanburg to St. Louis. 4 airlines have flights to Lambert-St Louis from Spartanburg on a regular basis. Booking flights from Spartanburg to Lambert-St Louis should not be difficult; the airport handles an average of 4 inbound flights from Spartanburg per day.

  • How popular is this Spartanburg to St. Louis flight route?

    This flight path from Spartanburg to Lambert-St Louis was viewed by 21 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to St. Louis?

    Airlines like Southwest and Delta fly from Spartanburg to St. Louis in about 4h 08m. The time it takes to get you to your destination can typically vary by up to 1h 32m. Spartanburg and St. Louis are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Spartanburg to St. Louis?

    No one likes to see their flight delayed. When booking a flight from Spartanburg to St. Louis consider choosing PSA Airlines (100%), Southwest (78%) or American Airlines (72%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Spartanburg to St. Louis?

    Looking for the cheapest flight from Spartanburg to St. Louis? While on average our users pay $243, our data indicates the cheapest price to be $118. The most popular route (Charlotte Douglas - Lambert-St Louis), is priced around $200.

  • Can I find deals for flights from Spartanburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Spartanburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to St. Louis.

  • Can I find deals for business class flights from Spartanburg to St. Louis?

    Yes. Cheapflights offers flight deals from Spartanburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $311). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Spartanburg to St. Louis

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Top 4 airlines flying from Spartanburg to St. Louis

Discover the top 4 airlines that operate flights from Spartanburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$132Average$205FlexibilityNo cancel feeOn-time62%
DeltaCheapest$198Average$346FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$347FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$221Average$357FlexibilityNo cancel feeOn-time63%

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