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$47+ Cheap flights from Spartanburg, SC to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — STL
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Lambert-St Louis are usually found in August or September, booked 74 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to St. Louis

Keep the following information in mind while searching for Spartanburg to St. Louis flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$119
(Mytrip)

One-way from

$47
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$387
Provider with most accurate pricing for Charlotte Douglas-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Lambert-St Louis flights.
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From Spartanburg to Lambert-St Louis
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One-way flight from Spartanburg to Lambert-St Louis
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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Spartanburg to St. Louis

Cheapest flights from Spartanburg to St. Louis
Explore the most affordable flight options available from Spartanburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:45 amCLT - STL
1 stop12h 48mFrontier
Tue 12/163:30 pmSTL - CLT
1 stop17h 20mFrontier
Deal found 11/4$119
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:20 pmCLT - STL
1 stop26h 13mFrontier
Thu 12/113:30 pmSTL - CLT
1 stop5h 08mFrontier
Deal found 11/3$120
This Booking.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:45 amCLT - STL
1 stop12h 48mFrontier
Wed 12/103:30 pmSTL - CLT
1 stop21h 11mFrontier
Deal found 11/5$121
This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:33 pmCLT - STL
1 stop11h 26mFrontier
Fri 12/53:30 pmSTL - CLT
1 stop5h 08mFrontier
Deal found 11/6$124
This Frontier deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:33 pmCLT - STL
1 stop11h 26mFrontier
Mon 12/89:54 amSTL - CLT
1 stop9h 31mFrontier
Deal found 11/5$128
This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:52 amCLT - STL
1 stop14h 41mFrontier
Mon 12/89:54 amSTL - CLT
1 stop9h 31mFrontier
Deal found 11/6$129
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:45 amCLT - STL
1 stop12h 48mFrontier
Tue 12/93:30 pmSTL - CLT
1 stop17h 20mFrontier
Deal found 11/4$133
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/182:27 pmCLT - STL
1 stop20h 38mFrontier
Fri 11/214:13 pmSTL - CLT
1 stop20h 13mFrontier
Deal found 11/4$136
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:33 pmCLT - STL
1 stop11h 26mFrontier
Sun 12/149:54 amSTL - CLT
1 stop22h 43mFrontier
Deal found 11/4$137
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/182:27 pmCLT - STL
1 stop20h 38mFrontier
Sat 11/224:13 pmSTL - CLT
1 stop14h 46mFrontier
Deal found 11/4$138
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/251:54 pmCLT - STL
1 stop20h 35mFrontier
Thu 11/274:13 pmSTL - CLT
1 stop15h 26mFrontier
Deal found 11/4$148
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:33 pmCLT - STL
1 stop25h 00mFrontier
Sun 12/149:54 amSTL - CLT
1 stop22h 43mFrontier
Deal found 11/4$154

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Spartanburg to St. Louis that are best for you.

Fly from

Spartanburg

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 12/8

9:20 pm-10:33 pm

1 stop26h 13m

Lambert-St Louis

Thu 12/11

3:30 pm-9:38 pm

1 stop5h 08m

$120

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 12/11

12:55 pm-2:05 pm

Nonstop2h 10m

Lambert-St Louis

Sun 12/14

4:15 pm-7:00 pm

Nonstop1h 45m

$181

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 12/12

6:25 pm-7:35 pm

Nonstop2h 10m

Lambert-St Louis

Wed 12/17

2:55 pm-5:40 pm

Nonstop1h 45m

$211

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sun 12/7

5:50 am-10:25 am

1 stop5h 35m

Lambert-St Louis

Tue 12/9

2:55 pm-5:40 pm

Nonstop1h 45m

$232

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 12/12

6:25 pm-7:35 pm

Nonstop2h 10m

Lambert-St Louis

Mon 12/15

2:55 pm-5:40 pm

Nonstop1h 45m

$233

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 12/10

6:33 am-10:45 am

1 stop5h 12m

Lambert-St Louis

Wed 12/17

2:02 pm-8:19 pm

1 stop5h 17m

$237

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 12/6

7:25 am-10:24 am

1 stop3h 59m

Lambert-St Louis

Sat 12/13

10:45 am-4:13 pm

1 stop4h 28m

$237

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 12/26

6:26 pm-7:30 pm

Nonstop2h 04m

Lambert-St Louis

Tue 1/6

3:54 pm-6:44 pm

Nonstop1h 50m

$240

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 12/26

5:09 pm-9:43 pm

1 stop5h 34m

Lambert-St Louis

Tue 1/6

8:30 am-2:13 pm

1 stop4h 43m

$242

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 12/8

12:55 pm-2:05 pm

Nonstop2h 10m

Lambert-St Louis

Thu 12/11

2:55 pm-5:40 pm

Nonstop1h 45m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 23 results
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Best time to book a flight from Spartanburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to St. Louis

How far ahead should I book a flight from Spartanburg to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to St. Louis. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to St. Louis, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to St. Louis?

Currently, June is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $108). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to STL?

Find hourly flight availability from Spartanburg to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 22% on flights from Spartanburg to St. Louis by exploring options for tickets at noon.

What is the cheapest day to fly from Spartanburg to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Spartanburg to St. Louis

Explore weekly flight availability from Spartanburg to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 6, 2025.

The most flights from SB1 to STL are scheduled on a Thursday (9 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

How much does it cost to fly round-trip from Spartanburg to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated November 6, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Spartanburg to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,004 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,041 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,116 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Spartanburg?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Spartanburg to St. Louis. 4 airlines have flights to Lambert-St Louis from Spartanburg on a regular basis. Booking flights from Spartanburg to Lambert-St Louis should not be difficult; the airport handles an average of 6 inbound flights from Spartanburg per day.

  • How popular is this Spartanburg to St. Louis flight route?

    This flight path from Spartanburg to Lambert-St Louis was viewed by 20 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to St. Louis?

    Airlines like Frontier and Southwest fly from Spartanburg to St. Louis in about 2h 10m. The time it takes to get you to your destination can typically vary by up to 24h 03m. Spartanburg and St. Louis are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Spartanburg to St. Louis?

    No one likes to see their flight delayed. When booking a flight from Spartanburg to St. Louis consider choosing Southwest (90%), American Airlines (85%) or British Airways (81%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Spartanburg to St. Louis?

    Looking for the cheapest flight from Spartanburg to St. Louis? While on average our users pay $263, our data indicates the cheapest price to be $145. The most popular route (Charlotte Douglas - Lambert-St Louis), is priced around $161.

  • Can I find deals for flights from Spartanburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Spartanburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to St. Louis.

  • Can I find deals for business class flights from Spartanburg to St. Louis?

    Yes. Cheapflights offers flight deals from Spartanburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to St. Louis?

    Currently, June is the cheapest month in which you can book a flight from Spartanburg to St. Louis (average of $108). Flying from Spartanburg to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Spartanburg to St. Louis

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Top 4 airlines flying from Spartanburg to St. Louis

Discover the top 4 airlines that operate flights from Spartanburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$132Average$212FlexibilityNo cancel feeOn-time62%
DeltaCheapest$173Average$332FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$341FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$217Average$396FlexibilityNo cancel feeOn-time63%

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