$99+ Cheap flights from St. Louis (STL) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
Jun 27 — Jul 41
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Spartanburg are usually found in January or August, booked 73 days in advance, depart on a Wednesday or Friday and return on a Saturday
Cheap flight deals from St. Louis to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to SpartanburgExplore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 28, 2026.
Explore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 28, 2026.
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Tue 6/301:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/26![Southwest logo]()
$197
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Wed 7/157:50 am
CLT
- STL
1 stop4h 40m
Southwest
Deal found 5/27![Southwest logo]()
$207
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
STL
- CLT
1 stop4h 32m
Delta
Tue 6/302:20 pm
CLT
- STL
1 stop4h 47m
Delta
Deal found 5/27![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:00 pm
STL
- CLT
Nonstop1h 50m
Southwest
Sat 10/246:40 am
CLT
- STL
1 stop3h 45m
Southwest
Deal found 5/26![Southwest logo]()
$219
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:54 am
STL
- CLT
Nonstop1h 55m
American Airlines
Wed 9/28:31 pm
CLT
- STL
1 stop4h 43m
American Airlines
Deal found 5/26![American Airlines logo]()
$228
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:58 pm
STL
- CLT
1 stop11h 17m
Frontier
Wed 8/261:12 pm
CLT
- STL
1 stop12h 02m
Frontier
Deal found 5/24![Frontier logo]()
$230
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:40 am
STL
- CLT
2 stops7h 55m
Southwest
Wed 7/221:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/25![Southwest logo]()
$232
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:40 pm
STL
- CLT
1 stop4h 30m
Southwest
Wed 6/241:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/23![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:35 am
STL
- CLT
2 stops8h 10m
Southwest
Tue 6/91:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/26![Southwest logo]()
$236
Best flights from St. Louis to SpartanburgDiscover carefully curated flight deals from St. Louis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 28, 2026.
Discover carefully curated flight deals from St. Louis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 28, 2026.
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:40 am
STL
- CLT
1 stop4h 30m
Southwest
Wed 7/11:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/23![Southwest logo]()
$227
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
STL
- CLT
1 stop4h 32m
Delta
Sun 6/215:30 am
CLT
- STL
1 stop3h 46m
Delta
Deal found 5/25![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
STL
- CLT
1 stop6h 50m
United Airlines
Sun 6/288:05 am
CLT
- STL
1 stop5h 06m
United Airlines
Deal found 5/26![United Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:40 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 6/224:40 pm
CLT
- STL
Nonstop2h 10m
Southwest
Deal found 5/27![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:20 am
STL
- CLT
1 stop5h 10m
Delta
Sun 9/1311:45 am
CLT
- STL
1 stop5h 12m
Delta
Deal found 5/25![Delta logo]()
$290
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Fri 6/194:40 pm
CLT
- STL
Nonstop2h 10m
Southwest
Deal found 5/27![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:13 pm
STL
- CLT
1 stop7h 16m
United Airlines
Thu 6/258:05 am
CLT
- STL
1 stop5h 06m
United Airlines
Deal found 5/23![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:39 pm
STL
- CLT
1 stop5h 41m
Delta
Tue 6/165:30 am
CLT
- STL
1 stop5h 16m
Delta
Deal found 5/25![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:35 pm
STL
- CLT
1 stop4h 40m
Southwest
Wed 6/107:50 am
CLT
- STL
1 stop4h 40m
Southwest
Deal found 5/24![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:12 pm
STL
- CLT
1 stop3h 47m
Delta
Mon 6/227:45 pm
CLT
- STL
1 stop5h 11m
Delta
Deal found 5/26![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:20 pm
STL
- CLT
1 stop6h 30m
Southwest
Sun 9/131:35 pm
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 5/25![Southwest logo]()
$294
Last-minute flights from St. Louis to SpartanburgDiscover last-minute flight deals from St. Louis to Spartanburg. Data last updated May 28, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Spartanburg. Data last updated May 28, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:35 am
STL
- CLT
2 stops8h 10m
Southwest
Tue 6/91:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/26![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:35 am
STL
- CLT
2 stops8h 10m
Southwest
Tue 6/301:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/24![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
STL
- CLT
1 stop4h 32m
Delta
Tue 6/236:59 am
CLT
- STL
1 stop3h 47m
Delta
Deal found 5/25![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:30 pm
STL
- CLT
1 stop6h 35m
Southwest
Tue 6/231:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/23![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Tue 6/301:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/26![Southwest logo]()
$197
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
STL
- CLT
1 stop4h 32m
Delta
Tue 6/302:20 pm
CLT
- STL
1 stop4h 47m
Delta
Deal found 5/27![Delta logo]()
$217
One-way flights from St. Louis to SpartanburgSearch for one-way flight options from St. Louis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated May 28, 2026.
Search for one-way flight options from St. Louis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated May 28, 2026.
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 5/27![Southwest logo]()
$99
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:58 pm
STL
- CLT
1 stop4h 59m
Delta
Deal found 5/27![Delta logo]()
$109
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 5/27![Southwest logo]()
$111
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:58 pm
STL
- CLT
1 stop11h 17m
Frontier
Deal found 5/24![Frontier logo]()
$115
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:00 am
STL
- CLT
1 stop4h 35m
Delta
Deal found 5/25![Delta logo]()
$119
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 5/24![Southwest logo]()
$120
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/64:40 pm
STL
- CLT
1 stop4h 30m
Southwest
Deal found 5/27![Southwest logo]()
$121
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:40 am
STL
- CLT
2 stops7h 55m
Southwest
Deal found 5/23![Southwest logo]()
$124
This Frontier deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:21 pm
STL
- CLT
1 stop9h 54m
Frontier
Deal found 5/27![Frontier logo]()
$129
Find flight deals from St. Louis to Spartanburg
Keep the following information in mind while searching for St. Louis to Spartanburg flight deals. Data was last updated May 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $197 (Southwest) |
One-way from | $99 (Southwest) |
Popular in | May |
Cheapest in | January |
Average price | $373 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 28, 2026.
Use the filters below to find and compare flights from St. Louis to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 7/1
5:40 am-11:10 am
1 stop4h 30m
Charlotte Douglas
Wed 7/1
1:25 pm-2:25 pm
Nonstop2h 00m
$227
Quickest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Fri 6/19
3:40 pm-6:30 pm
Nonstop1h 50m
Charlotte Douglas
Mon 6/22
4:40 pm-5:50 pm
Nonstop2h 10m
$271
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Tue 6/16
4:50 pm-7:40 pm
Nonstop1h 50m
Charlotte Douglas
Fri 6/19
4:40 pm-5:50 pm
Nonstop2h 10m
$275
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 6/17
6:00 am-11:32 am
1 stop4h 32m
Charlotte Douglas
Sun 6/21
5:30 am-8:16 am
1 stop3h 46m
$279
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 6/8
5:35 pm-11:15 pm
1 stop4h 40m
Charlotte Douglas
Wed 6/10
7:50 am-11:30 am
1 stop4h 40m
$281
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 9/10
7:20 am-1:30 pm
1 stop5h 10m
Charlotte Douglas
Sun 9/13
11:45 am-3:57 pm
1 stop5h 12m
$290
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 6/15
1:39 pm-8:20 pm
1 stop5h 41m
Charlotte Douglas
Tue 6/16
5:30 am-9:46 am
1 stop5h 16m
$293
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 9/10
2:20 pm-9:50 pm
1 stop6h 30m
Charlotte Douglas
Sun 9/13
1:35 pm-2:30 pm
Nonstop1h 55m
$294
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Fri 6/26
6:00 am-1:50 pm
1 stop6h 50m
Charlotte Douglas
Sun 6/28
8:05 am-12:11 pm
1 stop5h 06m
$311
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 6/22
1:13 pm-9:29 pm
1 stop7h 16m
Charlotte Douglas
Thu 6/25
8:05 am-12:11 pm
1 stop5h 06m
$311
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from St. Louis with our price prediction graph.
STL-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Spartanburg
STL-SB1
STL-CLT
What is the cheapest time of day to fly from STL to SB1?
Find hourly flight availability from St. Louis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 28, 2026.
One of the essential ways to save on airfare from St. Louis to Spartanburg is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 30% on airfare.
Weekly flight availability from St. Louis to Spartanburg
Explore weekly flight availability from St. Louis to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 28, 2026.
The most flights from STL to SB1 are scheduled on a Monday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from St. Louis to Spartanburg?
What is the cheapest day to fly from St. Louis to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spartanburg. Price data was last updated on May 23, 2026.
Travelers seeking maximum savings on their St. Louis to Spartanburg flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated May 28, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from St. Louis to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
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St. Louis and Spartanburg flights
Browse other St. Louis and Spartanburg flight options. Last updated on May 28, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on May 28, 2026.
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St. Louis to Spartanburg flights
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Top 4 airlines flying from St. Louis to Spartanburg
Discover the top 4 airlines that operate flights from St. Louis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$132 | Average$330 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$152 | Average$198 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$196 | Average$412 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$216 | Average$353 | FlexibilityNo cancel fee | On-time71% |