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St. Louis

$104+ Cheap flights from Mississippi to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
ene. 3 — ene. 101
sáb. 1/3
sáb. 1/10
1 adult, Economy
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Cheap flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 4, 2025.

This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:59 pmBTR - STL
1 stop4h 43mDelta
mié. 1/75:00 pmSTL - BTR
1 stop5h 01mDelta
Deal found 12/2$249
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:10 amBTR - STL
1 stop4h 39mUnited Airlines
mié. 1/711:20 amSTL - BTR
2 stops8h 13mUnited Airlines
Deal found 12/2$254
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/308:17 pmMEM - STL
1 stop26h 16mMultiple Airlines
mar. 1/65:11 pmSTL - MEM
1 stop26h 11mMultiple Airlines
Deal found 12/2$262
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:59 pmBTR - STL
1 stop4h 43mDelta
mar. 12/305:13 pmSTL - BTR
1 stop4h 40mDelta
Deal found 12/2$264
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:08 pmMEM - STL
1 stop26h 25mMultiple Airlines
mié. 1/77:43 pmSTL - MEM
2 stops40h 48mMultiple Airlines
Deal found 12/3$276
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/185:13 amMOB - STL
1 stop5h 43mAmerican Airlines
lun. 12/225:16 amSTL - MOB
1 stop4h 41mAmerican Airlines
Deal found 12/3$279
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/177:39 amBTR - STL
1 stop5h 18mDelta
dom. 12/215:13 pmSTL - BTR
1 stop4h 40mDelta
Deal found 12/2$279
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/147:39 amBTR - STL
1 stop5h 23mDelta
lun. 1/127:10 amSTL - BTR
1 stop6h 20mDelta
Deal found 12/1$294
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/145:31 amBTR - STL
2 stops7h 58mAmerican Airlines
lun. 1/123:54 pmSTL - BTR
1 stop5h 05mAmerican Airlines
Deal found 12/1$299
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/117:17 pmMOB - STL
1 stop4h 25mDelta
jue. 12/187:05 amSTL - MOB
1 stop5h 33mDelta
Deal found 12/4$309
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/153:57 pmBTR - STL
1 stop6h 01mUnited Airlines
lun. 12/226:00 amSTL - BTR
1 stop7h 07mUnited Airlines
Deal found 12/4$309
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/154:23 pmBTR - STL
2 stops7h 15mAmerican Airlines
lun. 12/227:00 amSTL - BTR
1 stop6h 48mAmerican Airlines
Deal found 12/4$314

Find flight deals from Mississippi to St. Louis

Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated diciembre 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$177
(American Airlines)

One-way from

$104
(Kiwi.com)

Popular in

May

Cheapest in

February

Average price

$384
Provider with most accurate pricing for Jackson-Evers Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Lambert-St Louis flights.
Search Deals
From Mississippi to Lambert-St Louis
Search Deals
One-way flight from Mississippi to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 4, 2025.
Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Fly from

Mississippi

Fly to

St. Louis

Route

Depart

Return

Price

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

jue. 1/15

8:19 pm-6:32 pm

1 stop22h 13m

Lambert-St Louis

sáb. 1/24

3:46 pm-2:17 pm

1 stop22h 31m

$163

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

mar. 1/27

2:51 pm-8:37 pm

1 stop5h 46m

Lambert-St Louis

mié. 1/28

9:59 am-4:09 pm

1 stop6h 10m

$177

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

vie. 1/23

3:12 pm-2:46 pm

1 stop23h 34m

Lambert-St Louis

lun. 2/9

8:22 pm-10:49 am

2 stops38h 27m

$198

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

lun. 3/2

6:50 pm-10:55 pm

1 stop4h 05m

Lambert-St Louis

mié. 3/4

8:15 am-2:40 pm

1 stop6h 25m

$199

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

jue. 1/15

8:19 pm-6:32 pm

1 stop22h 13m

Lambert-St Louis

sáb. 1/24

8:22 pm-7:28 pm

2 stops23h 06m

$199

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

lun. 1/26

1:25 pm-6:45 pm

1 stop5h 20m

Lambert-St Louis

mié. 1/28

6:50 am-2:40 pm

2 stops7h 50m

$204

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

sáb. 1/10

11:44 am-2:48 pm

2 stops27h 04m

Lambert-St Louis

sáb. 1/17

3:43 pm-7:15 pm

1 stop27h 32m

$212

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

mar. 1/27

5:14 pm-10:59 pm

1 stop5h 45m

Lambert-St Louis

mié. 1/28

11:05 am-11:45 pm

2 stops12h 40m

$224

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

sáb. 1/24

6:18 am-11:54 am

1 stop5h 36m

Lambert-St Louis

mar. 1/27

5:04 pm-10:01 pm

1 stop4h 57m

$249

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

lun. 12/29

6:59 pm-11:42 pm

1 stop4h 43m

Lambert-St Louis

mié. 1/7

5:00 pm-10:01 pm

1 stop5h 01m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 46 results
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Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis

What is the cheapest month to book a flight from Mississippi to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $209). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $410). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to STL?

Find hourly flight availability from Mississippi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 4, 2025.

A simple way to save on the total cost of your ticket is to fly from Mississippi to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 24% on your trip compared to booking a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Mississippi?

    For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How long is the flight from Mississippi to St. Louis?

    For as low as $199, Frontier can have you in St. Louis from Mississippi in 4h 05m. There are 445 mi between Mississippi and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $139 and $193 on Delta and Southwest, respectively.

  • What are the most popular routes from Mississippi to St. Louis?

    Most travelers choose Memphis - Lambert-St Louis, Mobile - Lambert-St Louis or Baton Rouge Ryan - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.

  • Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

  • Can I find deals for business class flights from Mississippi to St. Louis?

    Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $209). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $410). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Alternative routes for Mississippi to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to St. Louis

Discover the top 2 airlines that operate flights from Mississippi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$240Average$334FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$347FlexibilityNo cancel feeOn-time71%

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