How long is the flight from Mississippi to St. Louis?

For as low as $241, Frontier can have you in St. Louis from Mississippi in 6h 41m. There are 445 mi between Mississippi and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

For one-way options, check prices for Frontier. According to our data, you can fly for as low as $84. Users have also found prices from $123 and $128 on American Airlines and Spirit Airlines, respectively.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Mississippi to St. Louis?

Most travelers choose Jackson-Evers Intl - Lambert-St Louis, Memphis - Lambert-St Louis or Baton Rouge Ryan - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.

What is the cheapest month to fly from Mississippi to St. Louis?

Due to multiple factors, expect to potentially pay more when booking in May. For low rates, October can be a great choice for travel to St. Louis. Flights to St. Louis from Mississippi in October are about $356 on average during October, but can be found for as low as $226.

What airport do you fly into for flights to St. Louis from Mississippi?

For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

Can I find deals for business class flights from Mississippi to St. Louis?

Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$84+ Cheap Flights from Mississippi to St. Louis

Q: How much does it cost to fly round-trip from Mississippi to St. Louis?

Airfare is below average for this route at the moment. Mississippi to St. Louis flights typically cost between $317 and $385 in September. The cheapest round-trip price found within the last 3 days was $241 on Delta (Sep 9-Sep 13).

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Cheap flight deals from Mississippi to St. Louis

Round-trip from	$171 (FlightHub)
One-way from	$84 (FlightHub)
Popular in	May
Cheapest in	October
Average price	$301

From Mississippi to Lambert-St Louis

Search Deals

One-way flight from Mississippi to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 20% potential increase in price ($92 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($26 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

Thu 9/46:56 pmMEM - STL

1 stop14h 10mFrontier

Sun 9/77:55 pmSTL - MEM

1 stop18h 56mFrontier

Deal found 8/18

$171

Mon 8/257:53 pmMEM - STL

1 stop13h 18mFrontier

Wed 8/277:54 pmSTL - MEM

1 stop21h 31mFrontier

Deal found 8/19

$195

Sun 9/148:04 pmMEM - STL

1 stop13h 02mFrontier

Wed 9/177:55 pmSTL - MEM

1 stop22h 12mFrontier

Deal found 8/18

$199

Tue 9/95:50 amJAN - STL

1 stop6h 41mDelta

Sat 9/133:55 pmSTL - JAN

1 stop3h 35mDelta

Deal found 8/19

$241

Tue 9/91:15 pmJAN - STL

2 stops8h 10mSouthwest

Sat 9/137:00 amSTL - JAN

1 stop5h 30mSouthwest

Deal found 8/19

$246

Thu 12/42:15 pmGPT - STL

1 stop3h 47mDelta

Sun 12/76:00 amSTL - GPT

1 stop3h 38mDelta

Deal found 8/19

$249

Fri 9/124:39 pmBTR - STL

1 stop4h 36mDelta

Mon 9/151:26 pmSTL - BTR

1 stop4h 40mDelta

Deal found 8/19

$249

Tue 9/912:08 pmJAN - STL

2 stops8h 24mAmerican Airlines

Sat 9/136:10 amSTL - JAN

2 stops8h 52mAmerican Airlines

Deal found 8/19

$251

Tue 9/163:55 pmJAN - STL

1 stop6h 00mSouthwest

Fri 9/195:15 amSTL - JAN

1 stop6h 05mSouthwest

Deal found 8/19

$254

Fri 9/56:41 pmBTR - STL

1 stop4h 09mAmerican Airlines

Mon 9/155:18 amSTL - BTR

1 stop4h 20mAmerican Airlines

Deal found 8/18

$254

Thu 12/43:40 pmJAN - STL

1 stop6h 20mSouthwest

Sun 12/75:05 amSTL - JAN

1 stop6h 10mSouthwest

Deal found 8/19

$258

Thu 9/46:00 amGPT - STL

1 stop6h 26mDelta

Mon 9/85:11 pmSTL - GPT

1 stop4h 27mDelta

Deal found 8/19

$259

Best flights from Mississippi to St. Louis
Discover carefully curated flight deals from Mississippi to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 20, 2025.

Thu 9/46:56 pmMEM - STL

1 stop14h 10mFrontier

Sun 9/77:55 pmSTL - MEM

1 stop18h 56mFrontier

Deal found 8/18

$171

Tue 9/95:50 amJAN - STL

1 stop6h 41mDelta

Sat 9/133:55 pmSTL - JAN

1 stop3h 35mDelta

Deal found 8/19

$241

Tue 9/91:15 pmJAN - STL

2 stops8h 10mSouthwest

Sat 9/137:00 amSTL - JAN

1 stop5h 30mSouthwest

Deal found 8/19

$246

Fri 9/125:00 amBTR - STL

1 stop4h 57mUnited Airlines

Sun 9/146:15 amSTL - BTR

1 stop4h 56mUnited Airlines

Deal found 8/20

$249

Thu 9/256:32 pmBTR - STL

1 stop5h 21mAmerican Airlines

Sun 9/285:18 amSTL - BTR

1 stop4h 20mAmerican Airlines

Deal found 8/18

$249

Sat 9/137:00 amMEM - STL

2 stops26h 40mMultiple Airlines

Sun 9/141:52 pmSTL - MEM

1 stop9h 58mMultiple Airlines

Deal found 8/18

$286

Mon 8/257:53 pmMEM - STL

1 stop13h 18mFrontier

Wed 8/277:54 pmSTL - MEM

1 stop21h 31mFrontier

Deal found 8/19

$195

Mon 8/257:53 pmMEM - STL

1 stop13h 18mFrontier

Sat 8/307:54 pmSTL - MEM

1 stop23h 05mFrontier

Deal found 8/19

$195

Sun 9/148:04 pmMEM - STL

1 stop13h 02mFrontier

Wed 9/177:55 pmSTL - MEM

1 stop22h 12mFrontier

Deal found 8/18

$199

Wed 9/176:08 amGPT - STL

1 stop6h 13mDelta

Mon 9/221:26 pmSTL - GPT

1 stop3h 53mDelta

Deal found 8/18

$249

Tue 9/912:08 pmJAN - STL

2 stops8h 24mAmerican Airlines

Sat 9/136:10 amSTL - JAN

2 stops8h 52mAmerican Airlines

Deal found 8/19

$251

Tue 9/163:55 pmJAN - STL

1 stop6h 00mSouthwest

Fri 9/195:15 amSTL - JAN

1 stop6h 05mSouthwest

Deal found 8/19

$254

Last-minute flights from Mississippi to St. Louis
Discover last-minute flight deals from Mississippi to St. Louis. Data last updated August 20, 2025 and is based on user searches.

Mon 8/257:53 pmMEM - STL

1 stop13h 18mFrontier

Wed 8/277:54 pmSTL - MEM

1 stop21h 31mFrontier

Deal found 8/19

$195

Thu 9/46:56 pmMEM - STL

1 stop14h 10mFrontier

Sun 9/77:55 pmSTL - MEM

1 stop18h 56mFrontier

Deal found 8/18

$171

Thu 9/46:00 amGPT - STL

1 stop6h 26mDelta

Mon 9/85:11 pmSTL - GPT

1 stop4h 27mDelta

Deal found 8/19

$259

Thu 9/46:00 amMOB - STL

1 stop6h 26mDelta

Mon 9/85:11 pmSTL - MOB

1 stop6h 05mDelta

Deal found 8/19

$259

Fri 9/56:41 pmBTR - STL

1 stop4h 09mAmerican Airlines

Mon 9/155:18 amSTL - BTR

1 stop4h 20mAmerican Airlines

Deal found 8/18

$254

Tue 9/95:50 amJAN - STL

1 stop6h 41mDelta

Sat 9/133:55 pmSTL - JAN

1 stop3h 35mDelta

Deal found 8/19

$241

Tue 9/91:15 pmJAN - STL

2 stops8h 10mSouthwest

Sat 9/137:00 amSTL - JAN

1 stop5h 30mSouthwest

Deal found 8/19

$246

Tue 9/912:08 pmJAN - STL

2 stops8h 24mAmerican Airlines

Sat 9/136:10 amSTL - JAN

2 stops8h 52mAmerican Airlines

Deal found 8/19

$251

Fri 9/124:39 pmBTR - STL

1 stop4h 36mDelta

Mon 9/151:26 pmSTL - BTR

1 stop4h 40mDelta

Deal found 8/19

$249

Sun 9/148:04 pmMEM - STL

1 stop13h 02mFrontier

Wed 9/177:55 pmSTL - MEM

1 stop22h 12mFrontier

Deal found 8/18

$199

Tue 9/163:55 pmJAN - STL

1 stop6h 00mSouthwest

Fri 9/195:15 amSTL - JAN

1 stop6h 05mSouthwest

Deal found 8/19

$254

Wed 9/176:08 amGPT - STL

1 stop6h 13mDelta

Mon 9/221:26 pmSTL - GPT

1 stop3h 53mDelta

Deal found 8/18

$249

One-way flights from Mississippi to St. Louis
Search for one-way flight options from Mississippi to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 20, 2025.

Thu 9/46:56 pmMEM - STL

1 stop14h 10mFrontier

Deal found 8/18

$84

Thu 9/186:56 pmMEM - STL

1 stop14h 10mFrontier

Deal found 8/18

$117

Thu 9/187:25 amJAN - STL

1 stop8h 50mAmerican Airlines

Deal found 8/18

$123

Sat 9/137:00 amMEM - STL

2 stops26h 40mSpirit Airlines

Deal found 8/18

$128

Tue 9/167:00 amMEM - STL

1 stop8h 37mAmerican Airlines

Deal found 8/19

$144

Thu 10/27:00 amMEM - STL

2 stops26h 06mMultiple Airlines

Deal found 8/18

$148

Thu 9/185:40 amJAN - STL

2 stops7h 55mSouthwest

Deal found 8/18

$155

Sat 9/1310:42 amMEM - STL

1 stop11h 11mAmerican Airlines

Deal found 8/18

$159

Fri 10/37:00 amMEM - STL

1 stop13h 37mMultiple Airlines

Deal found 8/18

$160

Tue 9/163:01 pmMEM - STL

2 stops18h 05mMultiple Airlines

Deal found 8/19

$167

Fri 9/57:55 pmMEM - STL

2 stops37h 11mMultiple Airlines

Deal found 8/19

$176

Thu 9/187:00 amMEM - STL

2 stops26h 06mMultiple Airlines

Deal found 8/18

$177

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Thu 9/4

6:56 pm-9:06 am

1 stop14h 10m

Lambert-St Louis

Sun 9/7

7:55 pm-2:51 pm

1 stop18h 56m

$171

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Mon 8/25

7:53 pm-9:11 am

1 stop13h 18m

Lambert-St Louis

Wed 8/27

7:54 pm-5:25 pm

1 stop21h 31m

$195

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Mon 8/25

7:53 pm-9:11 am

1 stop13h 18m

Lambert-St Louis

Sat 8/30

7:54 pm-6:59 pm

1 stop23h 05m

$195

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Sun 9/14

8:04 pm-9:06 am

1 stop13h 02m

Lambert-St Louis

Wed 9/17

7:55 pm-6:07 pm

1 stop22h 12m

$199

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

Tue 9/9

5:50 am-12:31 pm

1 stop6h 41m

Lambert-St Louis

Sat 9/13

3:55 pm-7:30 pm

1 stop3h 35m

$241

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

Tue 9/9

1:15 pm-9:25 pm

2 stops8h 10m

Lambert-St Louis

Sat 9/13

7:00 am-12:30 pm

1 stop5h 30m

$246

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Fri 9/12

5:00 am-9:57 am

1 stop4h 57m

Lambert-St Louis

Sun 9/14

6:15 am-11:11 am

1 stop4h 56m

$249

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Thu 9/25

6:32 pm-11:53 pm

1 stop5h 21m

Lambert-St Louis

Sun 9/28

5:18 am-9:38 am

1 stop4h 20m

$249

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Wed 9/17

6:08 am-12:21 pm

1 stop6h 13m

Lambert-St Louis

Mon 9/22

1:26 pm-5:19 pm

1 stop3h 53m

$249

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Thu 12/4

6:00 pm-11:39 pm

1 stop5h 39m

Lambert-St Louis

Sun 12/7

6:00 am-9:38 am

1 stop3h 38m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 44 results

...

Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis

What is the cheapest month to book a flight from Mississippi to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to St. Louis as you normally would.

How much does it cost to fly round-trip from Mississippi to St. Louis?

Related info for your journey

What airport do you fly into for flights to St. Louis from Mississippi?
For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.
How long is the flight from Mississippi to St. Louis?
For as low as $241, Frontier can have you in St. Louis from Mississippi in 6h 41m. There are 445 mi between Mississippi and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from Mississippi to St. Louis one-way?
For one-way options, check prices for Frontier. According to our data, you can fly for as low as $84. Users have also found prices from $123 and $128 on American Airlines and Spirit Airlines, respectively.
What are the most popular routes from Mississippi to St. Louis?
Most travelers choose Jackson-Evers Intl - Lambert-St Louis, Memphis - Lambert-St Louis or Baton Rouge Ryan - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.
Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?
Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.
Can I find deals for business class flights from Mississippi to St. Louis?
Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mississippi to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

O'Fallon

Fairview Heights

Maryland Heights

Collinsville

Eureka

St. Peters

Glencoe

Alton

Chesterfield

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Mississippi to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$226	Average$290	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$246	Average$326	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$317	Average$438	FlexibilityNo cancel fee	On-time69%

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$84+ Cheap flights from Mississippi to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Mississippi to St. Louis

Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated August 20, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. LouisExplore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis

What is the cheapest month to book a flight from Mississippi to St. Louis?

What is the cheapest time of day to fly from MS to STL?

Find hourly flight availability from Mississippi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

How much does it cost to fly round-trip from Mississippi to St. Louis?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Mississippi?

How long is the flight from Mississippi to St. Louis?

What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

What are the most popular routes from Mississippi to St. Louis?

Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

How can I find direct flights from Mississippi to St. Louis?

Can I find deals for business class flights from Mississippi to St. Louis?

What is the cheapest month to book a flight from Mississippi to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Mississippi to St. Louis

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Top 3 airlines flying from Mississippi to St. Louis

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Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.