$85+ Cheap flights from Mississippi to St. Louis (STL)

For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

For as low as $279, American Airlines can have you in St. Louis from Mississippi in 4h 32m. There are 570 mi between Mississippi and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $163 and $193 on Delta and Southwest, respectively.

Most travelers choose Memphis - Lambert-St Louis, Baton Rouge Ryan - Lambert-St Louis or Jackson-Evers Intl - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.

Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.