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$109+ Cheap flights from Mississippi to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Mississippi to St. Louis

Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated July 3, 2025.

Round-trip from

$177
(Southwest)

One-way from

$109
(Mytrip)

Popular in

May

Cheapest in

November

Average price

$293
From Mississippi to Lambert-St Louis
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One-way flight from Mississippi to Lambert-St Louis
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Highest demand for flights based on searches. 22% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:40 amJAN - STL
1 stop4h 20mSouthwest
Mon 8/1811:00 amSTL - JAN
1 stop7h 00mSouthwest
Deal found 7/2$177
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/126:00 pmGPT - STL
1 stop4h 02mDelta
Sat 8/165:11 pmSTL - GPT
1 stop4h 27mDelta
Deal found 7/2$219
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/121:48 pmGPT - STL
2 stops8h 29mAmerican Airlines
Sat 8/167:19 amSTL - GPT
1 stop5h 42mAmerican Airlines
Deal found 7/2$224
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/255:34 pmMEM - STL
1 stop16h 06mSpirit Airlines
Sun 7/2710:47 amSTL - MEM
1 stop4h 20mSpirit Airlines
Deal found 7/1$242
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/77:48 pmMEM - STL
1 stop13h 23mMultiple Airlines
Sun 8/1010:47 amSTL - MEM
1 stop4h 20mMultiple Airlines
Deal found 7/1$249
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:59 pmMOB - STL
1 stop4h 15mDelta
Fri 8/225:11 pmSTL - MOB
1 stop6h 05mDelta
Deal found 7/1$249
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:49 pmBTR - STL
1 stop4h 25mDelta
Tue 8/199:17 amSTL - BTR
1 stop6h 36mDelta
Deal found 7/1$249
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/155:07 pmMOB - STL
1 stop5h 58mAmerican Airlines
Fri 8/2210:10 amSTL - MOB
2 stops10h 37mAmerican Airlines
Deal found 7/1$255
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:35 pmMEM - STL
2 stops7h 50mSouthwest
Sun 9/142:25 pmSTL - MEM
1 stop4h 35mSouthwest
Deal found 7/2$263
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:20 pmMEM - STL
1 stop4h 25mUnited Airlines
Sat 8/169:09 amSTL - MEM
1 stop5h 37mUnited Airlines
Deal found 7/2$303
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/83:35 pmJAN - STL
1 stop5h 59mDelta
Sun 8/107:11 pmSTL - JAN
1 stop4h 20mDelta
Deal found 7/2$307
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/185:10 amBTR - STL
1 stop4h 18mUnited Airlines
Tue 7/225:00 amSTL - BTR
2 stops8h 18mUnited Airlines
Deal found 7/3$320

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Fly from

Mississippi

Fly to

St. Louis

Route

Depart

Return

Price

JacksonSt. Louis

JAN - STL

JANSTL

Jackson-Evers Intl

Thu 8/7

5:40 am-10:00 am

1 stop4h 20m

Lambert-St Louis

Mon 8/18

11:00 am-6:00 pm

1 stop7h 00m

$177

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 8/12

6:00 pm-10:02 pm

1 stop4h 02m

Lambert-St Louis

Sat 8/16

5:11 pm-9:38 pm

1 stop4h 27m

$219

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 8/12

1:48 pm-10:17 pm

2 stops8h 29m

Lambert-St Louis

Sat 8/16

7:19 am-1:01 pm

1 stop5h 42m

$224

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 7/25

5:34 pm-9:40 am

1 stop16h 06m

Lambert-St Louis

Sun 7/27

10:47 am-3:07 pm

1 stop4h 20m

$242

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Thu 8/7

7:48 pm-9:11 am

1 stop13h 23m

Lambert-St Louis

Sun 8/10

10:47 am-3:07 pm

1 stop4h 20m

$249

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Fri 8/15

6:59 pm-11:14 pm

1 stop4h 15m

Lambert-St Louis

Fri 8/22

5:11 pm-11:16 pm

1 stop6h 05m

$249

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Thu 8/14

6:49 pm-11:14 pm

1 stop4h 25m

Lambert-St Louis

Tue 8/19

9:17 am-3:53 pm

1 stop6h 36m

$249

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Fri 8/15

5:07 pm-11:05 pm

1 stop5h 58m

Lambert-St Louis

Fri 8/22

10:10 am-8:47 pm

2 stops10h 37m

$255

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Thu 9/11

3:35 pm-11:25 pm

2 stops7h 50m

Lambert-St Louis

Sun 9/14

2:25 pm-7:00 pm

1 stop4h 35m

$263

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 8/15

6:20 pm-10:45 pm

1 stop4h 25m

Lambert-St Louis

Sat 8/16

9:09 am-2:46 pm

1 stop5h 37m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 34 results
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Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis

What is the cheapest month to book a flight from Mississippi to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to STL?

Find hourly flight availability from Mississippi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to St. Louis as you normally would.

How much does it cost to fly round-trip from Mississippi to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 3, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Mississippi to St. Louis. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Spirit Airlines
6.3
Okay
8,086 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Mississippi?

    For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $143. Users have also found prices from $158 and $164 on Spirit Airlines and American Airlines, respectively.

  • What are the most popular routes from Mississippi to St. Louis?

    Most travelers choose Memphis - Lambert-St Louis, Mobile - Lambert-St Louis or Gulfport Biloxi Regional - Lambert-St Louis when deciding on the best route from Mississippi to St. Louis.

  • Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

  • Can I find deals for business class flights from Mississippi to St. Louis?

    Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $311). Flying from Mississippi to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mississippi?

Book flights to Mississippi if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Festus
Chesterfield
Farmington

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Alternative routes for Mississippi to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to St. Louis

Discover the top 2 airlines that operate flights from Mississippi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$226Average$285FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$344FlexibilityNo cancel feeOn-timeN/A

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