St. Louis

$85+ Cheap flights from Mississippi to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
Feb 14 — Feb 211
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Cheap flight deals from Mississippi to St. Louis

Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$150
(Kiwi.com)

One-way from

$85
(Kiwi.com)
Provider with most accurate pricing for Jackson-Evers Intl-Lambert-St Louis flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Lambert-St Louis flights.
From Mississippi to Lambert-St Louis
One-way flight from Mississippi to Lambert-St Louis

Find flight deals from Mississippi to St. Louis

Cheapest flights from Mississippi to St. Louis
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:06 pm
MEM
-
STL
1 stop17h 50m
Multiple Airlines
Tue 3/33:49 pm
STL
-
MEM
1 stop18h 31m
Multiple Airlines
Deal found 1/13$150
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:06 pm
MEM
-
STL
1 stop17h 50m
Multiple Airlines
Tue 2/243:49 pm
STL
-
MEM
1 stop18h 31m
Multiple Airlines
Deal found 1/14$166
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/16:10 pm
MEM
-
STL
1 stop12h 41m
Frontier
Sat 2/78:22 pm
STL
-
MEM
1 stop20h 48m
Frontier
Deal found 1/14$175
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:15 am
MEM
-
STL
1 stop13h 12m
Multiple Airlines
Sat 2/282:51 pm
STL
-
MEM
1 stop28h 33m
Multiple Airlines
Deal found 1/14$184
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:06 pm
MEM
-
STL
1 stop17h 50m
Multiple Airlines
Fri 2/208:20 pm
STL
-
MEM
2 stops14h 00m
Multiple Airlines
Deal found 1/14$196
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:15 am
MEM
-
STL
1 stop11h 12m
Multiple Airlines
Fri 2/208:20 pm
STL
-
MEM
2 stops14h 00m
Multiple Airlines
Deal found 1/14$206
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:15 am
MEM
-
STL
1 stop21h 41m
Multiple Airlines
Sun 2/223:49 pm
STL
-
MEM
1 stop18h 31m
Multiple Airlines
Deal found 1/15$208
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1711:15 am
MEM
-
STL
2 stops19h 36m
Multiple Airlines
Mon 2/233:49 pm
STL
-
MEM
1 stop18h 31m
Multiple Airlines
Deal found 1/13$224
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2910:44 am
MOB
-
STL
1 stop5h 30m
American Airlines
Mon 2/23:54 pm
STL
-
MOB
1 stop7h 22m
American Airlines
Deal found 1/14$279
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:36 pm
BTR
-
STL
1 stop5h 01m
Delta
Mon 2/26:00 am
STL
-
BTR
1 stop6h 48m
Delta
Deal found 1/15$279
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/301:55 pm
BTR
-
STL
2 stops9h 03m
United Airlines
Mon 2/24:35 pm
STL
-
BTR
1 stop4h 57m
United Airlines
Deal found 1/15$284
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:33 pm
GPT
-
STL
1 stop4h 26m
American Airlines
Tue 2/176:18 pm
STL
-
GPT
1 stop4h 41m
American Airlines
Deal found 1/13$289

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.

Fly from

Mississippi

Fly to

St. Louis

Route

Depart

Return

Price

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 2/27

11:15 am-12:27 am

1 stop13h 12m

Lambert-St Louis

Sat 2/28

2:51 pm-7:24 pm

1 stop28h 33m

$184

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Wed 2/18

11:15 am-10:27 pm

1 stop11h 12m

Lambert-St Louis

Fri 2/20

8:20 pm-10:20 am

2 stops14h 00m

$206

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 2/27

8:06 pm-11:59 pm

2 stops27h 53m

Lambert-St Louis

Tue 3/3

3:49 pm-10:20 am

1 stop18h 31m

$213

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 2/20

8:06 pm-8:56 am

2 stops12h 50m

Lambert-St Louis

Tue 2/24

3:49 pm-10:20 am

1 stop18h 31m

$219

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Tue 2/17

11:15 am-6:51 am

2 stops19h 36m

Lambert-St Louis

Mon 2/23

3:49 pm-10:20 am

1 stop18h 31m

$224

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 2/13

8:06 pm-1:56 pm

1 stop17h 50m

Lambert-St Louis

Fri 2/20

3:49 pm-10:20 am

1 stop18h 31m

$227

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Fri 1/30

3:12 pm-2:46 pm

1 stop23h 34m

Lambert-St Louis

Sun 2/1

12:03 pm-2:17 pm

1 stop26h 14m

$242

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Sun 1/25

6:10 pm-6:51 am

1 stop12h 41m

Lambert-St Louis

Mon 1/26

8:22 pm-10:49 am

2 stops38h 27m

$275

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Thu 1/29

10:44 am-4:14 pm

1 stop5h 30m

Lambert-St Louis

Mon 2/2

3:54 pm-11:16 pm

1 stop7h 22m

$279

MobileSt. Louis

MOB - STL

MOBSTL

Mobile

Fri 1/30

7:05 pm-11:37 pm

1 stop4h 32m

Lambert-St Louis

Tue 2/3

9:59 am-3:11 pm

1 stop5h 12m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Showing 1-10 of 59 results
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Best time to book a flight from Mississippi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to St. Louis
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to St. Louis from Mississippi?

    For a flight from Mississippi to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How long is the flight from Mississippi to St. Louis?

    For as low as $279, American Airlines can have you in St. Louis from Mississippi in 4h 32m. There are 570 mi between Mississippi and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to St. Louis one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $163 and $193 on Delta and Southwest, respectively.

  • What are the most popular routes from Mississippi to St. Louis?

  • Can I find deals for flights from Mississippi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mississippi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to St. Louis.

  • Can I find deals for business class flights from Mississippi to St. Louis?

    Yes. Cheapflights offers flight deals from Mississippi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to St. Louis

Discover the top 2 airlines that operate flights from Mississippi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$240Average$369FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$340FlexibilityNo cancel feeOn-time71%

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