$101+ Cheap flights from Mississippi to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to St. Louis
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Cheapest flights from Mississippi to St. LouisExplore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
GPT
- STL
1 stop6h 54m
Delta
Mon 7/273:42 pm
STL
- GPT
1 stop6h 25m
Delta
Deal found 3/11![Delta logo]()
$257
This Frontier deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:47 pm
MEM
- STL
1 stop23h 45m
Frontier
Sat 4/258:17 pm
STL
- MEM
1 stop22h 45m
Frontier
Deal found 3/11![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/12![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:25 am
GPT
- STL
1 stop4h 51m
United Airlines
Wed 5/278:35 am
STL
- GPT
1 stop4h 50m
United Airlines
Deal found 3/14![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/15![Delta logo]()
$285
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:04 pm
BTR
- STL
1 stop4h 55m
Delta
Sun 5/106:00 am
STL
- BTR
1 stop6h 51m
Delta
Deal found 3/11![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:10 am
GPT
- STL
1 stop6h 11m
American Airlines
Mon 5/256:12 pm
STL
- GPT
1 stop5h 49m
American Airlines
Deal found 3/12![American Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:32 pm
BTR
- STL
1 stop4h 27m
American Airlines
Sun 5/105:20 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/14![American Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:42 pm
MEM
- STL
1 stop12h 08m
Multiple Airlines
Sat 4/258:23 pm
STL
- MEM
2 stops34h 52m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:07 am
BTR
- STL
1 stop5h 02m
Delta
Mon 4/67:03 am
STL
- BTR
1 stop5h 48m
Delta
Deal found 3/11![Delta logo]()
$305
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 pm
MOB
- STL
1 stop4h 23m
Delta
Mon 7/277:05 pm
STL
- MOB
1 stop3h 50m
Delta
Deal found 3/11![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:00 am
BTR
- STL
2 stops8h 39m
American Airlines
Mon 4/65:12 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/11![American Airlines logo]()
$310
Best flights from Mississippi to St. LouisDiscover carefully curated flight deals from Mississippi to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Mississippi to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
GPT
- STL
1 stop6h 54m
Delta
Mon 7/273:42 pm
STL
- GPT
1 stop6h 25m
Delta
Deal found 3/11![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:25 am
GPT
- STL
1 stop4h 51m
United Airlines
Wed 5/278:35 am
STL
- GPT
1 stop4h 50m
United Airlines
Deal found 3/14![United Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:32 pm
BTR
- STL
1 stop4h 27m
American Airlines
Sun 5/105:20 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/14![American Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:30 am
JAN
- STL
1 stop6h 00m
Southwest
Tue 4/712:40 pm
STL
- JAN
2 stops7h 40m
Southwest
Deal found 3/11![Southwest logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:43 pm
MEM
- STL
2 stops14h 07m
Multiple Airlines
Sun 4/264:59 pm
STL
- MEM
1 stop22h 41m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/14![Delta logo]()
$285
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:53 pm
BTR
- STL
1 stop6h 06m
American Airlines
Sun 4/125:20 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/15![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:57 pm
JAN
- STL
1 stop5h 30m
United Airlines
Tue 4/710:09 am
STL
- JAN
1 stop6h 03m
United Airlines
Deal found 3/11![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Tue 4/141:02 pm
STL
- GPT
1 stop4h 06m
Delta
Deal found 3/13![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:20 pm
JAN
- STL
1 stop4h 20m
Southwest
Sat 6/65:20 am
STL
- JAN
1 stop6h 20m
Southwest
Deal found 3/12![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:55 pm
GPT
- STL
1 stop5h 21m
United Airlines
Mon 3/306:00 am
STL
- GPT
1 stop7h 21m
United Airlines
Deal found 3/11![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:45 pm
JAN
- STL
1 stop4h 10m
Southwest
Mon 4/135:40 am
STL
- JAN
1 stop6h 00m
Southwest
Deal found 3/14![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:06 pm
JAN
- STL
1 stop4h 52m
Delta
Mon 4/136:50 pm
STL
- JAN
1 stop4h 25m
Delta
Deal found 3/12![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:45 am
MEM
- STL
2 stops8h 05m
Southwest
Wed 4/812:40 pm
STL
- MEM
2 stops8h 00m
Southwest
Deal found 3/11![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:08 pm
BTR
- STL
1 stop6h 20m
United Airlines
Wed 4/156:00 am
STL
- BTR
1 stop7h 25m
United Airlines
Deal found 3/10![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:01 pm
MOB
- STL
1 stop4h 58m
Delta
Tue 6/26:00 am
STL
- MOB
1 stop6h 05m
Delta
Deal found 3/13![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:55 pm
MEM
- STL
1 stop5h 15m
Southwest
Tue 4/215:35 am
STL
- MEM
1 stop6h 10m
Southwest
Deal found 3/14![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:15 pm
GPT
- STL
1 stop5h 12m
United Airlines
Tue 4/146:30 am
STL
- GPT
2 stops7h 43m
United Airlines
Deal found 3/10![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:20 pm
MEM
- STL
1 stop5h 35m
Southwest
Sat 5/95:15 am
STL
- MEM
2 stops7h 10m
Southwest
Deal found 3/13![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:55 pm
MOB
- STL
1 stop5h 32m
United Airlines
Tue 4/146:00 am
STL
- MOB
1 stop5h 50m
United Airlines
Deal found 3/10![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:57 pm
GPT
- STL
1 stop6h 01m
Delta
Fri 4/37:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/15![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:30 am
JAN
- STL
2 stops7h 20m
Southwest
Mon 4/62:35 pm
STL
- JAN
1 stop5h 05m
Southwest
Deal found 3/12![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:15 pm
GPT
- STL
1 stop5h 13m
United Airlines
Fri 4/176:00 am
STL
- GPT
1 stop7h 21m
United Airlines
Deal found 3/12![United Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:02 am
MEM
- STL
1 stop5h 30m
United Airlines
Wed 5/69:21 am
STL
- MEM
1 stop12h 43m
United Airlines
Deal found 3/12![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:25 pm
MEM
- STL
2 stops6h 45m
Southwest
Mon 5/258:25 am
STL
- MEM
2 stops8h 15m
Southwest
Deal found 3/11![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:01 pm
MOB
- STL
1 stop4h 58m
Delta
Sun 5/317:01 pm
STL
- MOB
1 stop4h 27m
Delta
Deal found 3/10![Delta logo]()
$464
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:02 am
MEM
- STL
1 stop5h 30m
United Airlines
Mon 5/255:41 pm
STL
- MEM
1 stop4h 18m
United Airlines
Deal found 3/11![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/194:20 pm
MEM
- STL
2 stops7h 25m
Southwest
Sat 4/255:15 am
STL
- MEM
2 stops7h 10m
Southwest
Deal found 3/11![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:09 pm
BTR
- STL
1 stop4h 19m
United Airlines
Thu 4/26:00 am
STL
- BTR
1 stop5h 21m
United Airlines
Deal found 3/13![United Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:30 am
JAN
- STL
1 stop6h 00m
Southwest
Sun 4/55:10 am
STL
- JAN
1 stop6h 25m
Southwest
Deal found 3/14![Southwest logo]()
$423
Last-minute flights from Mississippi to St. LouisDiscover last-minute flight deals from Mississippi to St. Louis. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to St. Louis. Data last updated March 15, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:07 am
BTR
- STL
1 stop5h 02m
Delta
Sat 4/46:00 am
STL
- BTR
1 stop6h 51m
Delta
Deal found 3/13![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:07 am
BTR
- STL
1 stop5h 02m
Delta
Mon 4/67:03 am
STL
- BTR
1 stop5h 48m
Delta
Deal found 3/11![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:00 am
BTR
- STL
2 stops8h 39m
American Airlines
Mon 4/65:12 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/11![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/15![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:57 pm
JAN
- STL
1 stop5h 30m
United Airlines
Tue 4/710:09 am
STL
- JAN
1 stop6h 03m
United Airlines
Deal found 3/11![United Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:14 am
MEM
- STL
1 stop12h 11m
Multiple Airlines
Wed 4/88:16 pm
STL
- MEM
1 stop17h 46m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/12![Delta logo]()
$265
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Tue 4/141:02 pm
STL
- GPT
1 stop4h 06m
Delta
Deal found 3/13![Delta logo]()
$312
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:06 pm
JAN
- STL
1 stop4h 52m
Delta
Mon 4/136:50 pm
STL
- JAN
1 stop4h 25m
Delta
Deal found 3/12![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:15 pm
GPT
- STL
1 stop5h 13m
United Airlines
Fri 4/176:00 am
STL
- GPT
1 stop7h 21m
United Airlines
Deal found 3/11![United Airlines logo]()
$331
This Frontier deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:47 pm
MEM
- STL
1 stop23h 45m
Frontier
Sat 4/258:17 pm
STL
- MEM
1 stop22h 45m
Frontier
Deal found 3/11![Frontier logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:42 pm
MEM
- STL
1 stop12h 08m
Multiple Airlines
Sat 4/258:23 pm
STL
- MEM
2 stops34h 52m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$302
One-way flights from Mississippi to St. LouisSearch for one-way flight options from Mississippi to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Mississippi to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:51 pm
MEM
- STL
1 stop24h 32m
Frontier
Deal found 3/15![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:30 pm
MEM
- STL
2 stops38h 20m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$135
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:00 pm
BTR
- STL
1 stop5h 19m
Delta
Deal found 3/12![Delta logo]()
$149
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:05 pm
BTR
- STL
1 stop4h 53m
Delta
Deal found 3/11![Delta logo]()
$153
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:06 am
BTR
- STL
2 stops8h 54m
American Airlines
Deal found 3/13![American Airlines logo]()
$154
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:00 pm
BTR
- STL
2 stops9h 11m
United Airlines
Deal found 3/11![United Airlines logo]()
$158
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:20 pm
MEM
- STL
1 stop5h 30m
Southwest
Deal found 3/14![Southwest logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:00 am
MEM
- STL
2 stops37h 21m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$184
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:25 am
JAN
- STL
1 stop7h 15m
Southwest
Deal found 3/12![Southwest logo]()
$189
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:00 pm
BTR
- STL
2 stops11h 57m
United Airlines
Deal found 3/10![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:23 pm
MEM
- STL
1 stop13h 56m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$190
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:36 pm
BTR
- STL
1 stop4h 17m
Delta
Deal found 3/14![Delta logo]()
$199
Find flight deals from Mississippi to St. Louis
Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated March 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $257 (Delta) |
One-way from | $101 (Booking.com) |
Popular in | May |
Cheapest in | February |
Average price | $577 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Thu 7/23
6:00 am-12:54 pm
1 stop6h 54m
Lambert-St Louis
Mon 7/27
3:42 pm-10:07 pm
1 stop6h 25m
$257
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Sun 5/24
9:25 am-2:16 pm
1 stop4h 51m
Lambert-St Louis
Wed 5/27
8:35 am-1:25 pm
1 stop4h 50m
$277
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Tue 4/7
5:57 pm-11:58 pm
1 stop6h 01m
Lambert-St Louis
Thu 4/9
7:03 am-2:00 pm
1 stop6h 57m
$285
Quickest round-trip
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Fri 5/8
6:32 pm-10:59 pm
1 stop4h 27m
Lambert-St Louis
Sun 5/10
5:20 am-10:02 am
1 stop4h 42m
$301
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Sat 4/11
4:53 pm-10:59 pm
1 stop6h 06m
Lambert-St Louis
Sun 4/12
5:20 am-10:02 am
1 stop4h 42m
$305
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Tue 4/7
5:57 pm-11:58 pm
1 stop6h 01m
Lambert-St Louis
Tue 4/14
1:02 pm-5:08 pm
1 stop4h 06m
$312
JacksonSt. Louis
JAN - STL
JANSTL
Jackson-Evers Intl
Thu 4/9
7:06 pm-11:58 pm
1 stop4h 52m
Lambert-St Louis
Mon 4/13
6:50 pm-11:15 pm
1 stop4h 25m
$325
JacksonSt. Louis
JAN - STL
JANSTL
Jackson-Evers Intl
Fri 4/3
4:57 pm-10:27 pm
1 stop5h 30m
Lambert-St Louis
Tue 4/7
10:09 am-4:12 pm
1 stop6h 03m
$329
JacksonSt. Louis
JAN - STL
JANSTL
Jackson-Evers Intl
Fri 4/3
5:30 am-11:30 am
1 stop6h 00m
Lambert-St Louis
Tue 4/7
12:40 pm-8:20 pm
2 stops7h 40m
$334
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Thu 3/26
4:55 pm-10:16 pm
1 stop5h 21m
Lambert-St Louis
Mon 3/30
6:00 am-1:21 pm
1 stop7h 21m
$341
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.
MEM-STL
BTR-STL
JAN-STL
MOB-STL
GPT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to St. Louis
USMS-STL
MEM-STL
BTR-STL
JAN-STL
MOB-STL
What is the cheapest month to book a flight from Mississippi to St. Louis?
Currently, March is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $242). Flying from Mississippi to St. Louis in December is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mississippi to St. Louis?
Related info for your journey
Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Mississippi and St. Louis flights
Browse other Mississippi and St. Louis flight options. Last updated on March 15, 2026.
Popular flight searches
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Mississippi to St. Louis flights
Consider these flights traveling from Mississippi to St. Louis.
Top 2 airlines flying from Mississippi to St. Louis
Discover the top 2 airlines that operate flights from Mississippi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$240 | Average$416 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$424 | FlexibilityNo cancel fee | On-time71% |