$112+ Cheap flights from Greenville to St. Louis (GSP - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
Jun 21 — Jun 281
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to St. Louis
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Cheapest flights from Greenville to St. LouisExplore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:30 pm
GSP
- STL
1 stop28h 29m
Multiple Airlines
Tue 8/46:33 pm
STL
- GSP
2 stops35h 55m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:50 pm
GSP
- STL
1 stop4h 10m
Southwest
Wed 8/510:15 am
STL
- GSP
1 stop5h 30m
Southwest
Deal found 5/19![Southwest logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:24 am
GSP
- STL
1 stop16h 25m
Multiple Airlines
Sun 6/284:17 pm
STL
- GSP
1 stop14h 17m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:30 pm
GSP
- STL
1 stop28h 29m
Multiple Airlines
Fri 8/74:52 pm
STL
- GSP
2 stops37h 36m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:30 pm
GSP
- STL
1 stop28h 29m
Multiple Airlines
Wed 8/54:52 pm
STL
- GSP
2 stops41h 34m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:30 pm
GSP
- STL
1 stop28h 29m
Multiple Airlines
Thu 8/66:33 pm
STL
- GSP
2 stops20h 34m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:25 am
GSP
- STL
1 stop16h 34m
Multiple Airlines
Tue 8/46:33 pm
STL
- GSP
2 stops35h 55m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:10 pm
GSP
- STL
2 stops42h 47m
Multiple Airlines
Sat 8/84:09 pm
STL
- GSP
1 stop14h 19m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:44 am
GSP
- STL
1 stop3h 35m
Delta
Sat 8/87:00 am
STL
- GSP
1 stop5h 45m
Delta
Deal found 5/19![Delta logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:25 am
GSP
- STL
1 stop16h 34m
Multiple Airlines
Fri 8/74:52 pm
STL
- GSP
2 stops37h 36m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$303
Best flights from Greenville to St. LouisDiscover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:50 pm
GSP
- STL
1 stop4h 10m
Southwest
Sun 6/286:40 am
STL
- GSP
1 stop5h 25m
Southwest
Deal found 5/19![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:35 pm
GSP
- STL
1 stop4h 25m
Southwest
Sun 6/2111:45 am
STL
- GSP
1 stop6h 05m
Southwest
Deal found 5/17![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:55 pm
GSP
- STL
1 stop7h 25m
Southwest
Wed 6/103:10 pm
STL
- GSP
1 stop5h 50m
Southwest
Deal found 5/19![Southwest logo]()
$367
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:55 pm
GSP
- STL
2 stops7h 55m
Southwest
Sat 6/135:10 am
STL
- GSP
1 stop7h 10m
Southwest
Deal found 5/21![Southwest logo]()
$367
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:50 pm
GSP
- STL
1 stop4h 55m
Southwest
Mon 7/275:35 pm
STL
- GSP
1 stop4h 15m
Southwest
Deal found 5/21![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:50 pm
GSP
- STL
1 stop4h 55m
Southwest
Sun 6/216:15 pm
STL
- GSP
1 stop4h 05m
Southwest
Deal found 5/18![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:30 am
GSP
- STL
2 stops8h 25m
Southwest
Sun 7/196:15 pm
STL
- GSP
1 stop4h 05m
Southwest
Deal found 5/21![Southwest logo]()
$392
Last-minute flights from Greenville to St. LouisDiscover last-minute flight deals from Greenville to St. Louis. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to St. Louis. Data last updated May 22, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:55 pm
GSP
- STL
2 stops7h 55m
Southwest
Wed 6/103:10 pm
STL
- GSP
1 stop5h 50m
Southwest
Deal found 5/17![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:25 am
GSP
- STL
2 stops11h 00m
Southwest
Mon 6/152:15 pm
STL
- GSP
2 stops7h 35m
Southwest
Deal found 5/19![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:50 pm
GSP
- STL
1 stop6h 25m
Southwest
Mon 6/155:50 am
STL
- GSP
1 stop6h 25m
Southwest
Deal found 5/19![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:50 pm
GSP
- STL
1 stop4h 55m
Southwest
Sat 6/132:30 pm
STL
- GSP
1 stop5h 45m
Southwest
Deal found 5/21![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:35 pm
GSP
- STL
1 stop4h 25m
Southwest
Sun 6/213:05 pm
STL
- GSP
2 stops7h 15m
Southwest
Deal found 5/17![Southwest logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:48 pm
GSP
- STL
2 stops26h 42m
Multiple Airlines
Sun 6/284:17 pm
STL
- GSP
1 stop14h 17m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:50 pm
GSP
- STL
1 stop4h 10m
Southwest
Sun 6/286:40 am
STL
- GSP
1 stop5h 25m
Southwest
Deal found 5/19![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:19 am
GSP
- STL
2 stops25h 33m
Multiple Airlines
Sun 6/284:17 pm
STL
- GSP
1 stop14h 17m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:24 am
GSP
- STL
1 stop16h 25m
Multiple Airlines
Sun 6/284:17 pm
STL
- GSP
1 stop14h 17m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$275
One-way flights from Greenville to St. LouisSearch for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/173:48 pm
GSP
- STL
2 stops26h 42m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$112
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:15 am
GSP
- STL
1 stop4h 17m
American Airlines
Deal found 5/18![American Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1910:26 am
GSP
- STL
2 stops23h 26m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$171
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 pm
GSP
- STL
1 stop3h 10m
Southwest
Deal found 5/19![Southwest logo]()
$189
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:20 am
GSP
- STL
1 stop6h 55m
American Airlines
Deal found 5/19![American Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:25 am
GSP
- STL
2 stops35h 58m
Multiple Airlines
Deal found 5/21![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:44 pm
GSP
- STL
3 stops22h 52m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$227
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:30 pm
GSP
- STL
1 stop5h 27m
American Airlines
Deal found 5/21![American Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:25 pm
GSP
- STL
1 stop7h 34m
American Airlines
Deal found 5/20![American Airlines logo]()
$234
Find flight deals from Greenville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $264 (Kiwi.com) |
One-way from | $112 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 6/24
7:50 pm-11:00 pm
1 stop4h 10m
Lambert-St Louis
Sun 6/28
6:40 am-1:05 pm
1 stop5h 25m
$327
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 6/17
7:35 pm-11:00 pm
1 stop4h 25m
Lambert-St Louis
Sun 6/21
11:45 am-6:50 pm
1 stop6h 05m
$337
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Mon 6/8
1:55 pm-8:20 pm
1 stop7h 25m
Lambert-St Louis
Wed 6/10
3:10 pm-10:00 pm
1 stop5h 50m
$367
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Thu 6/11
1:55 pm-8:50 pm
2 stops7h 55m
Lambert-St Louis
Sat 6/13
5:10 am-1:20 pm
1 stop7h 10m
$367
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Fri 7/24
6:50 pm-10:45 pm
1 stop4h 55m
Lambert-St Louis
Mon 7/27
5:35 pm-10:50 pm
1 stop4h 15m
$387
Quickest round-trip
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Thu 6/18
6:50 pm-10:45 pm
1 stop4h 55m
Lambert-St Louis
Sun 6/21
6:15 pm-11:20 pm
1 stop4h 05m
$387
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Thu 7/16
8:30 am-3:55 pm
2 stops8h 25m
Lambert-St Louis
Sun 7/19
6:15 pm-11:20 pm
1 stop4h 05m
$392
Cheapest one-way
Quickest one-way
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 6/17
5:15 am-8:32 am
1 stop4h 17m
$134
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Fri 6/19
10:26 am-8:52 am
2 stops23h 26m
$171
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Sun 7/5
7:30 pm-11:55 pm
1 stop5h 25m
$194
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Greenville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to St. Louis in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
GSP-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to St. Louis
What is the cheapest month to book a flight from Greenville to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $298). Flying from Greenville to St. Louis in January is currently the most expensive (average of $666). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 22, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Greenville to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Find flights from Greenville to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and St. Louis flights
Browse other Greenville and St. Louis flight options. Last updated on May 22, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
Popular flight searches
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
Top 2 airlines flying from Greenville to St. Louis
Discover the top 2 airlines that operate flights from Greenville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$471 | FlexibilityNo cancel fee | On-time71% |