$126+ Cheap flights from Greenville to St. Louis (GSP - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
Apr 25 — May 21
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to St. LouisExplore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Wed 4/2211:35 am
STL
- GSP
1 stop3h 45m
Southwest
Deal found 3/23![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:59 pm
GSP
- STL
1 stop4h 37m
Delta
Tue 4/217:25 am
STL
- GSP
1 stop3h 56m
Delta
Deal found 3/23![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:25 pm
GSP
- STL
1 stop5h 50m
Southwest
Mon 4/277:35 am
STL
- GSP
1 stop3h 25m
Southwest
Deal found 3/23![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:25 pm
GSP
- STL
1 stop3h 30m
Southwest
Tue 4/211:15 pm
STL
- GSP
2 stops7h 25m
Southwest
Deal found 3/23![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:25 pm
GSP
- STL
1 stop3h 30m
Southwest
Sat 4/182:25 pm
STL
- GSP
1 stop5h 15m
Southwest
Deal found 3/21![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:50 pm
GSP
- STL
1 stop4h 29m
Delta
Sun 4/266:00 am
STL
- GSP
1 stop5h 21m
Delta
Deal found 3/24![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:40 am
GSP
- STL
1 stop3h 30m
Delta
Sat 5/236:45 am
STL
- GSP
1 stop4h 10m
Delta
Deal found 3/24![Delta logo]()
$338
Best flights from Greenville to St. LouisDiscover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Wed 4/2211:35 am
STL
- GSP
1 stop3h 45m
Southwest
Deal found 3/23![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:59 pm
GSP
- STL
1 stop4h 37m
Delta
Tue 4/217:25 am
STL
- GSP
1 stop3h 56m
Delta
Deal found 3/23![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:41 pm
GSP
- STL
1 stop4h 45m
United Airlines
Mon 6/299:23 am
STL
- GSP
1 stop6h 37m
United Airlines
Deal found 3/25![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:25 pm
GSP
- STL
1 stop5h 50m
Southwest
Mon 4/277:35 am
STL
- GSP
1 stop3h 25m
Southwest
Deal found 3/23![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:50 pm
GSP
- STL
1 stop4h 29m
Delta
Sun 4/266:00 am
STL
- GSP
1 stop3h 20m
Delta
Deal found 3/23![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:05 pm
GSP
- STL
1 stop5h 40m
Southwest
Wed 4/152:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Deal found 3/23![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:05 pm
GSP
- STL
1 stop3h 10m
Southwest
Thu 5/211:45 pm
STL
- GSP
2 stops7h 30m
Southwest
Deal found 3/21![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:50 pm
GSP
- STL
1 stop6h 15m
Southwest
Mon 6/295:50 am
STL
- GSP
1 stop6h 25m
Southwest
Deal found 3/25![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 pm
GSP
- STL
1 stop3h 10m
Southwest
Fri 5/291:45 pm
STL
- GSP
2 stops7h 30m
Southwest
Deal found 3/21![Southwest logo]()
$388
Last-minute flights from Greenville to St. LouisDiscover last-minute flight deals from Greenville to St. Louis. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to St. Louis. Data last updated March 26, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:05 pm
GSP
- STL
1 stop5h 40m
Southwest
Wed 4/152:30 pm
STL
- GSP
1 stop6h 10m
Southwest
Deal found 3/23![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:05 pm
GSP
- STL
1 stop5h 55m
Southwest
Wed 4/2211:35 am
STL
- GSP
1 stop3h 45m
Southwest
Deal found 3/23![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:59 pm
GSP
- STL
1 stop4h 37m
Delta
Tue 4/217:25 am
STL
- GSP
1 stop3h 56m
Delta
Deal found 3/23![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:25 pm
GSP
- STL
1 stop3h 30m
Southwest
Tue 4/211:15 pm
STL
- GSP
2 stops7h 25m
Southwest
Deal found 3/23![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:25 pm
GSP
- STL
1 stop5h 50m
Southwest
Mon 4/277:35 am
STL
- GSP
1 stop3h 25m
Southwest
Deal found 3/23![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:50 pm
GSP
- STL
1 stop4h 29m
Delta
Sun 4/266:00 am
STL
- GSP
1 stop5h 21m
Delta
Deal found 3/24![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:12 pm
GSP
- STL
1 stop6h 47m
American Airlines
Sun 4/265:51 am
STL
- GSP
1 stop4h 10m
American Airlines
Deal found 3/22![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:59 pm
GSP
- STL
1 stop4h 37m
Delta
Sun 4/266:00 am
STL
- GSP
1 stop3h 20m
Delta
Deal found 3/23![Delta logo]()
$345
One-way flights from Greenville to St. LouisSearch for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:09 pm
GSP
- STL
1 stop4h 01m
Delta
Deal found 3/24![Delta logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:28 pm
GSP
- STL
2 stops24h 55m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$152
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:05 pm
GSP
- STL
1 stop3h 10m
Southwest
Deal found 3/21![Southwest logo]()
$164
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
GSP
- STL
1 stop6h 13m
American Airlines
Deal found 3/25![American Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- STL
3 stops30h 42m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$190
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:41 pm
GSP
- STL
1 stop4h 32m
United Airlines
Deal found 3/24![United Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:25 am
GSP
- STL
2 stops8h 10m
Southwest
Deal found 3/24![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:12 pm
GSP
- STL
3 stops34h 46m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:14 pm
GSP
- STL
3 stops45h 25m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$809
Find flight deals from Greenville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $251 (Southwest) |
One-way from | $126 (Delta) |
Popular in | January |
Cheapest in | October |
Average price | $439 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Tue 4/14
5:05 pm-10:00 pm
1 stop5h 55m
Lambert-St Louis
Wed 4/22
11:35 am-4:20 pm
1 stop3h 45m
$251
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Fri 4/17
7:59 pm-11:36 pm
1 stop4h 37m
Lambert-St Louis
Tue 4/21
7:25 am-12:21 pm
1 stop3h 56m
$302
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Mon 4/20
6:25 pm-11:15 pm
1 stop5h 50m
Lambert-St Louis
Mon 4/27
7:35 am-12:00 pm
1 stop3h 25m
$310
Quickest round-trip
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 4/22
5:50 pm-9:19 pm
1 stop4h 29m
Lambert-St Louis
Sun 4/26
6:00 am-10:20 am
1 stop3h 20m
$319
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Sun 4/12
7:05 pm-11:45 pm
1 stop5h 40m
Lambert-St Louis
Wed 4/15
2:30 pm-9:40 pm
1 stop6h 10m
$359
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Tue 5/19
5:05 pm-7:15 pm
1 stop3h 10m
Lambert-St Louis
Thu 5/21
1:45 pm-10:15 pm
2 stops7h 30m
$363
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Thu 6/25
5:41 pm-9:26 pm
1 stop4h 45m
Lambert-St Louis
Mon 6/29
9:23 am-5:00 pm
1 stop6h 37m
$387
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Thu 6/25
6:50 pm-12:05 am
1 stop6h 15m
Lambert-St Louis
Mon 6/29
5:50 am-1:15 pm
1 stop6h 25m
$387
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 5/27
5:05 pm-7:15 pm
1 stop3h 10m
Lambert-St Louis
Fri 5/29
1:45 pm-10:15 pm
2 stops7h 30m
$388
Cheapest one-way
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 5/20
1:09 pm-4:10 pm
1 stop4h 01m
$126
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Greenville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to St. Louis in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
GSP-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to St. Louis
What is the cheapest month to book a flight from Greenville to St. Louis?
Currently, June is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $108). Flying from Greenville to St. Louis in February is currently the most expensive (average of $245). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated March 26, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Greenville to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Greenville and St. Louis flights
Browse other Greenville and St. Louis flight options. Last updated on March 26, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on March 26, 2026.
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Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 26, 2026.
Top 3 airlines flying from Greenville to St. Louis
Discover the top 3 airlines that operate flights from Greenville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$183 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$446 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$367 | FlexibilityNo cancel fee | On-time63% |