How popular is this Fort Myers to St. Louis flight route?

Flights from Fort Myers SW Florida Intl to Lambert-St Louis have been viewed 16 times in the past calendar month.

What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $177. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $186 and $196, respectively. Users have found that Southwest is 55% cheaper than the other options available to this destination.

What is the cheapest day to fly from Fort Myers to St. Louis?

Travelers seeking maximum savings on their Fort Myers to St. Louis flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the cheapest flights from Fort Myers to St. Louis?

While on average a flight from Fort Myers to St. Louis is generally $294, our data shows the cheapest flight currently is $88. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $163 for that flight.

What are the most popular airlines that fly from Fort Myers to St. Louis?

American Airlines, Delta and Southwest are the most popular airlines when flying from Fort Myers to St. Louis.

What is the cheapest day to fly round-trip from Fort Myers to St. Louis?

Travelers have found that booking a Wednesday departure is the best way to save up to 26% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Fort Myers to St. Louis?

To save up to 293% on this flight, we recommend booking at least 58 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Fort Myers to St. Louis from $378 1-2 weeks out and tickets from $618 for flights departing within the next 72 hours.

What is the cheapest month to fly from Fort Myers to St. Louis?

August can be a great time to fly to St. Louis from Fort Myers with a flight ticket averaging about $394. Cheapflights users have found deals in the month of August for as cheap as $147. The most expensive prices can be found in the month of February.

What airports do I use to fly from Fort Myers to St. Louis?

If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There is 1 flight from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 30m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.

Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.

Can I find deals for business class flights from Fort Myers to St. Louis?

Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$69+ Cheap Flights from Fort Myers to St. Louis

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Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in August or July, booked 58 days in advance, depart on a Thursday or Wednesday and return on a Wednesday

Cheap flight deals from Fort Myers to St. Louis

Round-trip from	$163 (Southwest)
One-way from	$69 (Southwest)
Popular in	February
Cheapest in	August
Average price	$241

From Fort Myers SW Florida Intl to Lambert-St Louis

Search Deals

One-way flight from Fort Myers SW Florida Intl to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($61 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Wed 10/228:00 amRSW - STL

Nonstop2h 35mSouthwest

Tue 10/286:40 pmSTL - RSW

Nonstop2h 20mSouthwest

Deal found 8/14

$163

Thu 11/137:30 amRSW - STL

Nonstop2h 40mSouthwest

Mon 11/178:15 amSTL - RSW

Nonstop2h 25mSouthwest

Deal found 8/14

$177

Wed 11/127:50 amRSW - STL

Nonstop2h 40mSouthwest

Sun 11/165:10 amSTL - RSW

1 stop9h 20mSouthwest

Deal found 8/14

$179

Thu 9/118:00 amRSW - STL

1 stop8h 25mAmerican Airlines

Tue 9/167:16 amSTL - RSW

1 stop5h 34mAmerican Airlines

Deal found 8/15

$187

Wed 10/221:00 pmRSW - STL

1 stop8h 14mAmerican Airlines

Tue 10/286:00 amSTL - RSW

2 stops8h 54mAmerican Airlines

Deal found 8/14

$198

Best flights from Fort Myers to St. Louis
Discover carefully curated flight deals from Fort Myers to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2025.

Wed 10/228:00 amRSW - STL

Nonstop2h 35mSouthwest

Tue 10/286:40 pmSTL - RSW

Nonstop2h 20mSouthwest

Deal found 8/14

$163

Thu 9/112:37 pmRSW - STL

1 stop7h 29mAmerican Airlines

Thu 9/187:22 amSTL - RSW

1 stop7h 10mAmerican Airlines

Deal found 8/14

$187

Wed 11/127:50 amRSW - STL

Nonstop2h 40mSouthwest

Sun 11/168:10 pmSTL - RSW

Nonstop2h 25mSouthwest

Deal found 8/14

$163

Thu 9/118:15 amRSW - STL

1 stop4h 42mAmerican Airlines

Tue 9/167:16 amSTL - RSW

1 stop5h 34mAmerican Airlines

Deal found 8/14

$187

Thu 11/137:30 amRSW - STL

Nonstop2h 40mSouthwest

Mon 11/178:15 amSTL - RSW

Nonstop2h 25mSouthwest

Deal found 8/14

$177

Last-minute flights from Fort Myers to St. Louis
Discover last-minute flight deals from Fort Myers to St. Louis. Data last updated August 16, 2025 and is based on user searches.

Thu 8/217:22 pmRSW - STL

1 stop18h 34mMultiple Airlines

Mon 8/252:30 pmSTL - RSW

1 stop17h 08mMultiple Airlines

Deal found 8/14

$279

Thu 8/217:22 pmRSW - STL

1 stop18h 34mMultiple Airlines

Thu 8/282:30 pmSTL - RSW

1 stop17h 08mMultiple Airlines

Deal found 8/14

$289

Thu 8/2112:04 pmRSW - STL

1 stop6h 06mAmerican Airlines

Mon 8/256:01 amSTL - RSW

2 stops8h 42mAmerican Airlines

Deal found 8/15

$384

Thu 8/216:50 pmRSW - STL

Nonstop2h 35mSouthwest

Thu 8/282:00 pmSTL - RSW

1 stop6h 55mSouthwest

Deal found 8/14

$552

Thu 8/217:05 amRSW - STL

2 stops9h 39mUnited Airlines

Mon 8/256:35 amSTL - RSW

2 stops8h 22mUnited Airlines

Deal found 8/15

$584

Fri 8/229:15 amRSW - STL

1 stop6h 18mUnited Airlines

Sun 8/248:10 amSTL - RSW

1 stop5h 34mUnited Airlines

Deal found 8/15

$449

Sun 8/248:58 pmRSW - STL

2 stops16h 58mFrontier

Wed 8/277:54 pmSTL - RSW

2 stops13h 26mFrontier

Deal found 8/15

$389

Thu 8/285:35 amRSW - STL

1 stop4h 40mDelta

Sun 8/315:11 pmSTL - RSW

1 stop6h 25mDelta

Deal found 8/14

$247

Fri 9/56:50 pmRSW - STL

Nonstop2h 35mSouthwest

Tue 9/96:40 pmSTL - RSW

Nonstop2h 25mSouthwest

Deal found 8/14

$210

Fri 9/57:40 amRSW - STL

Nonstop2h 30mSouthwest

Mon 9/87:55 amSTL - RSW

Nonstop2h 25mSouthwest

Deal found 8/14

$240

Fri 9/511:14 amRSW - STL

2 stops8h 08mAmerican Airlines

Tue 9/97:23 amSTL - RSW

2 stops7h 20mAmerican Airlines

Deal found 8/14

$245

Wed 9/1011:15 amRSW - STL

1 stop6h 34mDelta

Mon 9/156:01 amSTL - RSW

1 stop4h 46mDelta

Deal found 8/14

$213

One-way flights from Fort Myers to St. Louis
Search for one-way flight options from Fort Myers to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 16, 2025.

Tue 9/168:05 amRSW - STL

Nonstop2h 30mSouthwest

Deal found 8/15

$69

Thu 9/186:10 pmRSW - STL

1 stop6h 15mSouthwest

Deal found 8/15

$79

Sun 9/147:24 pmRSW - STL

1 stop20h 40mFrontier

Deal found 8/15

$84

Sun 9/217:24 pmRSW - STL

1 stop20h 40mFrontier

Deal found 8/13

$86

Thu 8/217:22 pmRSW - STL

1 stop18h 34mFrontier

Deal found 8/14

$91

Tue 9/168:00 amRSW - STL

1 stop6h 23mAmerican Airlines

Deal found 8/15

$94

Wed 9/178:05 amRSW - STL

Nonstop2h 30mSouthwest

Deal found 8/14

$95

Tue 9/165:35 amRSW - STL

1 stop5h 24mDelta

Deal found 8/16

$99

Wed 9/177:00 amRSW - STL

1 stop6h 21mDelta

Deal found 8/14

$100

Wed 9/171:09 pmRSW - STL

2 stops8h 23mAmerican Airlines

Deal found 8/15

$105

Mon 9/156:50 pmRSW - STL

Nonstop2h 35mSouthwest

Deal found 8/15

$109

Sun 9/147:50 amRSW - STL

Nonstop2h 30mSouthwest

Deal found 8/15

$114

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 10/22

8:00 am-9:35 am

Nonstop2h 35m

Lambert-St Louis

Tue 10/28

6:40 pm-10:00 pm

Nonstop2h 20m

$163

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 11/12

7:50 am-9:30 am

Nonstop2h 40m

Lambert-St Louis

Sun 11/16

8:10 pm-11:35 pm

Nonstop2h 25m

$163

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 11/13

7:30 am-9:10 am

Nonstop2h 40m

Lambert-St Louis

Mon 11/17

8:15 am-11:40 am

Nonstop2h 25m

$177

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 9/11

2:37 pm-9:06 pm

1 stop7h 29m

Lambert-St Louis

Thu 9/18

7:22 am-3:32 pm

1 stop7h 10m

$187

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 9/11

8:15 am-11:57 am

1 stop4h 42m

Lambert-St Louis

Tue 9/16

7:16 am-1:50 pm

1 stop5h 34m

$187

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 12/4

7:50 am-9:30 am

Nonstop2h 40m

$69

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 10/30

7:25 am-9:00 am

Nonstop2h 35m

$69

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 11/4

7:50 am-9:30 am

Nonstop2h 40m

$69

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 10/21

6:25 pm-8:00 pm

Nonstop2h 35m

$69

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 10/2

11:50 am-1:30 pm

Nonstop2h 40m

$69

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 11 results

The best insider tips for Fort Myers to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Fort Myers to St. Louis trip

Airports

RSW

During peak tourist seasons, plan an extra 20 minutes at RSW for check-in due to smaller airline ticket counters.

STL

Use the MetroLink light rail for a convenient and economical way to reach downtown St. Louis from STL.

Our travel experts

Matt Meltzer

Expert on RSW

Taryn White

Expert on STL

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

The best time to book flights from Fort Myers to St. Louis is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Fort Myers to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $311). Flying from Fort Myers to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to STL?

One of the essential ways to save on airfare from Fort Myers to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 12% on airfare.

Reviews of airlines servicing St. Louis

Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,246 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

8.0

Very good

7,985 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from Fort Myers to St. Louis?
If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There is 1 flight from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 30m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.
How popular is this Fort Myers to St. Louis flight route?
Flights from Fort Myers SW Florida Intl to Lambert-St Louis have been viewed 16 times in the past calendar month.
What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?
Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $177. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $186 and $196, respectively. Users have found that Southwest is 55% cheaper than the other options available to this destination.
What are the cheapest flights from Fort Myers to St. Louis?
While on average a flight from Fort Myers to St. Louis is generally $294, our data shows the cheapest flight currently is $88. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $163 for that flight.
Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?
Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.
Can I find deals for business class flights from Fort Myers to St. Louis?
Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $311). Flying from Fort Myers to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Eureka

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Glencoe

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Chesterfield

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Top 3 airlines flying from Fort Myers to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Southwest	Cheapest$177	Average$378	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$186	Average$320	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$196	Average$364	FlexibilityNo cancel fee	On-timeN/A

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$69+ Cheap flights from Fort Myers to St. Louis (RSW - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in August or July, booked 58 days in advance, depart on a Thursday or Wednesday and return on a Wednesday

Cheap flight deals from Fort Myers to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. LouisExplore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

The best insider tips for Fort Myers to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Fort Myers to St. Louis trip

Airports

RSW

STL

Our travel experts

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to St. Louis. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Fort Myers to St. Louis?

What is the cheapest time of day to fly from RSW to STL?

Find hourly flight availability from Fort Myers to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

Reviews of airlines servicing St. Louis

Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Fort Myers to St. Louis?

How popular is this Fort Myers to St. Louis flight route?

What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

What are the cheapest flights from Fort Myers to St. Louis?

Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

How can I find direct flights from Fort Myers to St. Louis?

Can I find deals for business class flights from Fort Myers to St. Louis?

What is the cheapest month to book a flight from Fort Myers to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Fort Myers to St. Louis

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Top 3 airlines flying from Fort Myers to St. Louis

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Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.