How popular is this Fort Myers to St. Louis flight route?

Flights from Fort Myers SW Florida Intl to Lambert-St Louis have been viewed 19 times in the past calendar month.

How long is the flight from Fort Myers to St. Louis?

A quick flight from Fort Myers to St. Louis can take about 5h 05m. Frontier provides one of the quickest options available for as low as $299. The distance from Fort Myers to St. Louis is about 980 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $177. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $181 and $196, respectively. Users have found that Southwest is 52% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?

The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Fort Myers to St. Louis for a low price.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the cheapest flights from Fort Myers to St. Louis?

While on average a flight from Fort Myers to St. Louis is generally $338, our data shows the cheapest flight currently is $122. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $299 for that flight.

What are the most popular airlines that fly from Fort Myers to St. Louis?

Southwest, Delta and American Airlines are the most popular airlines when flying from Fort Myers to St. Louis.

Most accurate provider : When it comes to deals on Fort Myers-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Fort Myers to St. Louis?

If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There are 2 flights from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 40m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.

Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.

Can I find deals for business class flights from Fort Myers to St. Louis?

Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$67+ Flights from Fort Myers to St. Louis

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Find cheap flights from Fort Myers to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in August or November, booked 32 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Sun 12/287:00 amRSW - STL

1 stop6h 27mUnited Airlines

Fri 1/211:05 amSTL - RSW

1 stop6h 24mUnited Airlines

Deal found 12/21

$403

Tue 12/304:27 pmRSW - STL

1 stop7h 16mUnited Airlines

Thu 1/13:10 pmSTL - RSW

1 stop5h 42mUnited Airlines

Deal found 12/21

$447

Sun 12/2112:27 pmRSW - STL

1 stop7h 51mUnited Airlines

Fri 1/28:05 amSTL - RSW

2 stops12h 44mUnited Airlines

Deal found 12/21

$478

Sun 12/286:40 amRSW - STL

1 stop5h 45mSouthwest

Fri 1/28:55 amSTL - RSW

2 stops9h 35mSouthwest

Deal found 12/21

$504

Sun 12/214:27 pmRSW - STL

1 stop7h 16mUnited Airlines

Mon 12/229:55 amSTL - RSW

2 stops10h 50mUnited Airlines

Deal found 12/21

$513

Sun 12/2811:37 amRSW - STL

2 stops12h 06mUnited Airlines

Sun 1/46:30 amSTL - RSW

2 stops8h 11mUnited Airlines

Deal found 12/21

$611

Mon 12/224:27 pmRSW - STL

1 stop7h 16mUnited Airlines

Wed 12/248:15 amSTL - RSW

1 stop6h 26mUnited Airlines

Deal found 12/22

$626

Best flights from Fort Myers to St. Louis
Discover carefully curated flight deals from Fort Myers to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

Thu 4/91:13 pmRSW - STL

1 stop21h 49mFrontier

Sun 4/1210:42 amSTL - RSW

1 stop6h 47mFrontier

Deal found 12/22

$248

Wed 1/287:04 amRSW - STL

1 stop8h 39mAmerican Airlines

Thu 2/59:54 amSTL - RSW

1 stop6h 23mAmerican Airlines

Deal found 12/23

$297

Fri 2/137:25 amRSW - STL

Nonstop2h 45mSouthwest

Sun 2/157:00 pmSTL - RSW

Nonstop2h 25mSouthwest

Deal found 12/22

$299

Sat 2/211:53 pmRSW - STL

1 stop6h 37mAmerican Airlines

Mon 2/231:36 pmSTL - RSW

1 stop6h 09mAmerican Airlines

Deal found 12/22

$299

Wed 2/45:00 pmRSW - STL

Nonstop2h 50mSouthwest

Thu 2/512:30 pmSTL - RSW

1 stop7h 00mSouthwest

Deal found 12/21

$299

Wed 1/287:50 amRSW - STL

Nonstop2h 45mSouthwest

Thu 2/512:30 pmSTL - RSW

1 stop7h 00mSouthwest

Deal found 12/23

$299

Fri 2/138:08 amRSW - STL

1 stop5h 38mAmerican Airlines

Sun 2/153:31 pmSTL - RSW

1 stop6h 04mAmerican Airlines

Deal found 12/22

$299

Tue 1/207:50 amRSW - STL

Nonstop2h 45mSouthwest

Tue 1/2712:05 pmSTL - RSW

Nonstop2h 35mSouthwest

Deal found 12/21

$309

Last-minute flights from Fort Myers to St. Louis
Discover last-minute flight deals from Fort Myers to St. Louis. Data last updated December 23, 2025 and is based on user searches.

Thu 1/16:20 amRSW - STL

1 stop11h 03mAmerican Airlines

Mon 1/123:37 pmSTL - RSW

1 stop6h 13mAmerican Airlines

Deal found 12/21

$338

Tue 1/66:35 pmRSW - STL

1 stop5h 37mAmerican Airlines

Sat 1/109:54 amSTL - RSW

1 stop6h 23mAmerican Airlines

Deal found 12/21

$351

Wed 1/78:36 amRSW - STL

1 stop7h 07mAmerican Airlines

Mon 1/126:00 amSTL - RSW

1 stop5h 33mAmerican Airlines

Deal found 12/22

$333

Wed 1/141:12 pmRSW - STL

1 stop6h 22mAmerican Airlines

Mon 1/196:52 amSTL - RSW

1 stop6h 25mAmerican Airlines

Deal found 12/22

$305

Wed 1/147:03 amRSW - STL

2 stops10h 00mUnited Airlines

Mon 1/196:30 amSTL - RSW

1 stop5h 59mUnited Airlines

Deal found 12/22

$380

Tue 1/206:35 pmRSW - STL

1 stop5h 37mAmerican Airlines

Tue 1/273:40 pmSTL - RSW

1 stop6h 10mAmerican Airlines

Deal found 12/21

$295

Tue 1/207:50 amRSW - STL

Nonstop2h 45mSouthwest

Tue 1/276:20 amSTL - RSW

1 stop9h 40mSouthwest

Deal found 12/21

$309

Wed 1/287:04 amRSW - STL

1 stop8h 39mAmerican Airlines

Thu 2/59:54 amSTL - RSW

1 stop6h 23mAmerican Airlines

Deal found 12/23

$297

Wed 1/287:50 amRSW - STL

Nonstop2h 45mSouthwest

Thu 2/512:30 pmSTL - RSW

1 stop7h 00mSouthwest

Deal found 12/23

$299

One-way flights from Fort Myers to St. Louis
Search for one-way flight options from Fort Myers to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 23, 2025.

Fri 2/202:41 pmRSW - STL

1 stop17h 10mFrontier

Deal found 12/21

$67

Thu 1/297:36 pmRSW - STL

1 stop12h 15mFrontier

Deal found 12/21

$98

Tue 1/207:31 amRSW - STL

2 stops24h 20mMultiple Airlines

Deal found 12/20

$102

Thu 1/297:36 pmRSW - STL

2 stops28h 57mMultiple Airlines

Deal found 12/21

$103

Thu 1/227:36 pmRSW - STL

2 stops15h 47mFrontier

Deal found 12/22

$106

Mon 2/236:00 amRSW - STL

2 stops41h 27mMultiple Airlines

Deal found 12/21

$110

Sat 2/216:00 amRSW - STL

2 stops18h 59mMultiple Airlines

Deal found 12/22

$113

Wed 1/217:31 amRSW - STL

3 stops41h 02mMultiple Airlines

Deal found 12/22

$119

Thu 2/199:31 pmRSW - STL

2 stops36h 25mFrontier

Deal found 12/21

$123

Sat 1/247:45 pmRSW - STL

2 stops38h 36mMultiple Airlines

Deal found 12/22

$125

Find flight deals from Fort Myers to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$248 (Expedia)
One-way from	$67 (Kiwi.com)
Popular in	February
Cheapest in	August
Average price	$518

Provider with most accurate pricing for Fort Myers SW Florida Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Lambert-St Louis flights.

Search Deals

From Fort Myers SW Florida Intl to Lambert-St Louis

Search Deals

One-way flight from Fort Myers SW Florida Intl to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 19% potential increase in price ($89 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 4/9

1:13 pm-10:02 am

1 stop21h 49m

Lambert-St Louis

Sun 4/12

10:42 am-6:29 pm

1 stop6h 47m

$248

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 1/28

7:04 am-2:43 pm

1 stop8h 39m

Lambert-St Louis

Thu 2/5

9:54 am-5:17 pm

1 stop6h 23m

$297

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Fri 2/13

7:25 am-9:10 am

Nonstop2h 45m

Lambert-St Louis

Sun 2/15

7:00 pm-10:25 pm

Nonstop2h 25m

$299

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Sat 2/21

1:53 pm-7:30 pm

1 stop6h 37m

Lambert-St Louis

Mon 2/23

1:36 pm-8:45 pm

1 stop6h 09m

$299

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 2/4

5:00 pm-6:50 pm

Nonstop2h 50m

Lambert-St Louis

Thu 2/5

12:30 pm-8:30 pm

1 stop7h 00m

$299

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 1/28

7:50 am-9:35 am

Nonstop2h 45m

Lambert-St Louis

Thu 2/5

12:30 pm-8:30 pm

1 stop7h 00m

$299

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Fri 2/13

8:08 am-12:46 pm

1 stop5h 38m

Lambert-St Louis

Sun 2/15

3:31 pm-10:35 pm

1 stop6h 04m

$299

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 1/20

7:50 am-9:35 am

Nonstop2h 45m

Lambert-St Louis

Tue 1/27

12:05 pm-3:40 pm

Nonstop2h 35m

$309

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 1/22

7:36 pm-6:51 am

1 stop12h 15m

$98

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Mon 2/23

6:00 am-10:27 pm

2 stops41h 27m

$110

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 17 results

Compare providers for flights from Fort Myers to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to St. Louis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Priceline	Price Accuracy1 star	Trust Score*3 stars
JustAirTicket	Price Accuracy-	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Fort Myers-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

The best time to book flights from Fort Myers to St. Louis is 32 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Fort Myers to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $147). Flying from Fort Myers to St. Louis in April is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to STL?

One of the essential ways to save on airfare from Fort Myers to St. Louis is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 8% on airfare.

The best insider tips for Fort Myers to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Fort Myers to St. Louis trip

Airports

RSW

During peak tourist seasons, plan an extra 20 minutes at RSW for check-in due to smaller airline ticket counters.

STL

Use the MetroLink light rail for a convenient and economical way to reach downtown St. Louis from STL.

Our travel experts

Matt Meltzer

Expert on RSW

Taryn White

Expert on STL

Reviews of airlines servicing St. Louis

Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,253 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,014 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airports do I use to fly from Fort Myers to St. Louis?
If you wish to fly to St. Louis from Fort Myers, then you need to book flights from Fort Myers SW Florida Intl to Lambert-St Louis. There are 2 flights from SW Florida Intl (RSW) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from SW Florida Intl are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 2h 40m is how long a nonstop flight from Fort Myers to Lambert-St Louis typically takes.
How popular is this Fort Myers to St. Louis flight route?
Flights from Fort Myers SW Florida Intl to Lambert-St Louis have been viewed 19 times in the past calendar month.
How long is the flight from Fort Myers to St. Louis?
A quick flight from Fort Myers to St. Louis can take about 5h 05m. Frontier provides one of the quickest options available for as low as $299. The distance from Fort Myers to St. Louis is about 980 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?
Flying on Southwest is currently your cheapest option to St. Louis, with prices starting at $177. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $181 and $196, respectively. Users have found that Southwest is 52% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?
The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Fort Myers to St. Louis for a low price.
What are the cheapest flights from Fort Myers to St. Louis?
While on average a flight from Fort Myers to St. Louis is generally $338, our data shows the cheapest flight currently is $122. When looking at the most popular route, (Fort Myers SW Florida Intl - Lambert-St Louis), you can expect to pay $299 for that flight.
Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?
Yes. In addition to deals on Fort Myers to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to St. Louis.
Can I find deals for business class flights from Fort Myers to St. Louis?
Yes. Cheapflights offers flight deals from Fort Myers to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Fort Myers to St. Louis (average of $147). Flying from Fort Myers to St. Louis in April is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

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Other flights to St. Louis

Top 3 airlines flying from Fort Myers to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Southwest	Cheapest$177	Average$359	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$181	Average$296	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$196	Average$356	FlexibilityNo cancel fee	On-timeN/A

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$67+ Cheap flights from Fort Myers to St. Louis (RSW - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Lambert-St Louis are usually found in August or November, booked 32 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Fort Myers to St. Louis

Cheapest flights from Fort Myers to St. LouisExplore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Find flight deals from Fort Myers to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to St. Louis that are best for you.

Compare providers for flights from Fort Myers to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to St. Louis in December.

Best time to book a flight from Fort Myers to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to St. Louis

How far ahead should I book a flight from Fort Myers to St. Louis?

What is the cheapest month to book a flight from Fort Myers to St. Louis?

What is the cheapest time of day to fly from RSW to STL?

The best insider tips for Fort Myers to St. Louis flights

AI-powered summary based on content written by travel experts. AI can make mistakes.

Cheapflights partnered with top experts to bring you the best recommendations for your Fort Myers to St. Louis trip

Airports

RSW

STL

Our travel experts

Reviews of airlines servicing St. Louis

Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Fort Myers to St. Louis?

How popular is this Fort Myers to St. Louis flight route?

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What are the cheapest airlines flying from Fort Myers to St. Louis round-trip?

What are the cheapest airlines to fly from Fort Myers to St. Louis one-way?

What are the cheapest flights from Fort Myers to St. Louis?

Can I find deals for flights from Fort Myers to St. Louis that include hotel bookings?

How can I find direct flights from Fort Myers to St. Louis?

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Alternative routes for Fort Myers to St. Louis

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Top 3 airlines flying from Fort Myers to St. Louis

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Cheapest flights from Fort Myers to St. Louis
Explore the most affordable flight options available from Fort Myers to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.