$65+ Cheap flights from Detroit to St. Louis (DTT - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — STL
Jun 4 — Jun 111
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit All airports to Lambert-St Louis are usually found in August or July, booked 42 days in advance, depart on a Thursday or Friday and return on a Friday
Cheap flight deals from Detroit to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to St. LouisExplore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
DTW
- STL
1 stop11h 43m
Frontier
Sun 6/76:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/4![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Fri 6/125:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Deal found 5/4![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/1![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:50 am
DTW
- STL
1 stop11h 43m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/4![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
DTW
- STL
1 stop12h 03m
Multiple Airlines
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$137
This Travelocity deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/268:08 pm
STL
- DTW
1 stop15h 27m
Frontier
Deal found 4/30![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/3![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:45 am
DTW
- STL
1 stop27h 07m
Frontier
Tue 9/16:33 pm
STL
- DTW
1 stop5h 09m
Frontier
Deal found 5/3![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Thu 6/46:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/2![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/85:27 pm
STL
- DTW
2 stops17h 08m
Frontier
Deal found 5/2![Frontier logo]()
$159
This Frontier deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:44 pm
DTW
- STL
1 stop12h 13m
Frontier
Wed 5/275:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/2![Frontier logo]()
$160
Best flights from Detroit to St. LouisDiscover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
Discover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Tue 6/96:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/3![Delta logo]()
$197
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:35 pm
DTW
- STL
1 stop5h 40m
Southwest
Mon 6/17:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/4![Southwest logo]()
$223
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:13 am
DTW
- STL
2 stops12h 08m
United Airlines
Wed 6/36:00 am
STL
- DTW
2 stops7h 34m
United Airlines
Deal found 5/1![United Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Mon 6/16:04 pm
STL
- DTW
Nonstop1h 33m
Delta
Deal found 4/30![Delta logo]()
$213
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:25 pm
DTW
- STL
2 stops8h 35m
Southwest
Sat 6/612:50 pm
STL
- DTW
2 stops9h 55m
Southwest
Deal found 5/3![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:36 pm
DTW
- STL
Nonstop1h 40m
Delta
Fri 6/510:19 am
STL
- DTW
Nonstop1h 31m
Delta
Deal found 5/1![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:40 pm
DTW
- STL
2 stops7h 20m
Southwest
Fri 6/1211:25 am
STL
- DTW
2 stops8h 35m
Southwest
Deal found 5/4![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:05 am
DTW
- STL
1 stop5h 41m
United Airlines
Wed 5/271:13 pm
STL
- DTW
2 stops9h 38m
United Airlines
Deal found 4/30![United Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:36 pm
DTW
- STL
Nonstop1h 40m
Delta
Sun 5/316:45 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/2![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:25 pm
DTW
- STL
2 stops8h 35m
Southwest
Sun 6/76:00 am
STL
- DTW
2 stops8h 00m
Southwest
Deal found 5/4![Southwest logo]()
$349
Last-minute flights from Detroit to St. LouisDiscover last-minute flight deals from Detroit to St. Louis. Data last updated May 5, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to St. Louis. Data last updated May 5, 2026 and is based on user searches.
This Travelocity deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/268:08 pm
STL
- DTW
1 stop15h 27m
Frontier
Deal found 4/30![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:44 pm
DTW
- STL
1 stop12h 13m
Frontier
Wed 5/275:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/2![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:50 am
DTW
- STL
1 stop11h 43m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/4![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/1![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/3![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Thu 6/46:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/2![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Fri 6/125:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Deal found 5/4![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
DTW
- STL
1 stop11h 43m
Frontier
Sun 6/76:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/4![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
DTW
- STL
1 stop12h 03m
Multiple Airlines
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/85:27 pm
STL
- DTW
2 stops17h 08m
Frontier
Deal found 5/2![Frontier logo]()
$159
One-way flights from Detroit to St. LouisSearch for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
Search for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Deal found 5/5![Frontier logo]()
$65
This Expedia deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:44 pm
DTW
- STL
1 stop12h 13m
Frontier
Deal found 5/1![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Deal found 5/1![Frontier logo]()
$77
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:20 pm
DTW
- STL
1 stop7h 03m
Frontier
Deal found 5/1![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:19 pm
DTW
- STL
1 stop7h 04m
Frontier
Deal found 5/1![Frontier logo]()
$95
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:55 am
DTW
- STL
1 stop12h 28m
Frontier
Deal found 5/1![Frontier logo]()
$96
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Deal found 5/1![Southwest logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:38 pm
DTW
- STL
1 stop16h 14m
Frontier
Deal found 5/4![Frontier logo]()
$100
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 am
DTW
- STL
1 stop12h 23m
Frontier
Deal found 4/30![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:30 am
DTW
- STL
1 stop27h 22m
Frontier
Deal found 5/3![Frontier logo]()
$104
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:10 pm
DTW
- STL
Nonstop1h 45m
Southwest
Deal found 5/1![Southwest logo]()
$107
This Priceline deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:31 pm
DTW
- STL
1 stop5h 02m
Frontier
Deal found 4/30![Frontier logo]()
$111
Find flight deals from Detroit to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $124 (Kiwi.com) |
One-way from | $65 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $257 |
Good round-trip deal | $360 or less |
Good one-way deal | $187 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/2
12:31 pm-1:10 pm
Nonstop1h 39m
Lambert-St Louis
Tue 6/9
6:30 am-9:04 am
Nonstop1h 34m
$197
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 5/28
12:31 pm-1:10 pm
Nonstop1h 39m
Lambert-St Louis
Mon 6/1
6:04 pm-8:37 pm
Nonstop1h 33m
$213
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 5/28
3:35 pm-8:15 pm
1 stop5h 40m
Lambert-St Louis
Mon 6/1
7:40 pm-10:10 pm
Nonstop1h 30m
$223
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 6/5
1:25 pm-9:00 pm
2 stops8h 35m
Lambert-St Louis
Sat 6/6
12:50 pm-11:45 pm
2 stops9h 55m
$275
Quickest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 5/29
4:36 pm-5:16 pm
Nonstop1h 40m
Lambert-St Louis
Fri 6/5
10:19 am-12:50 pm
Nonstop1h 31m
$277
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/2
10:13 am-9:21 pm
2 stops12h 08m
Lambert-St Louis
Wed 6/3
6:00 am-2:34 pm
2 stops7h 34m
$292
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 6/3
1:40 pm-8:00 pm
2 stops7h 20m
Lambert-St Louis
Fri 6/12
11:25 am-9:00 pm
2 stops8h 35m
$309
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 5/29
4:36 pm-5:16 pm
Nonstop1h 40m
Lambert-St Louis
Sun 5/31
6:45 am-9:19 am
Nonstop1h 34m
$319
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 6/5
1:25 pm-9:00 pm
2 stops8h 35m
Lambert-St Louis
Sun 6/7
6:00 am-3:00 pm
2 stops8h 00m
$349
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 5/26
11:05 am-3:46 pm
1 stop5h 41m
Lambert-St Louis
Wed 5/27
1:13 pm-11:51 pm
2 stops9h 38m
$360
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Detroit to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to St. Louis in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.
DTT-STL
DTW-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to St. Louis
DTT-STL
DTW-STL
How far ahead should I book a flight from Detroit to St. Louis?
The price you pay for your flight from Detroit to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Detroit to St. Louis?
Currently, June is the cheapest month in which you can book a flight from Detroit to St. Louis (average of $26). Flying from Detroit to St. Louis in April is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to STL?
Find hourly flight availability from Detroit to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 5, 2026.
When flying from Detroit to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the morning.
What is the cheapest day to fly from Detroit to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Detroit to St. Louis. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Detroit to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Detroit to St. Louis
Explore weekly flight availability from Detroit to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 5, 2026.
The most flights from DTT to STL are scheduled on a Monday (18 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Detroit to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 5, 2026.
See what other customers who have flown with Southwest,Delta, andSpirit Airlines from Detroit to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Detroit and St. Louis flights
Browse other Detroit and St. Louis flight options. Last updated on May 5, 2026.
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Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on May 5, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 5, 2026.
Top 4 airlines flying from Detroit to St. Louis
Discover the top 4 airlines that operate flights from Detroit to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$98 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$250 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$357 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$149 | Average$325 | FlexibilityNo cancel fee | On-time63% |