$89+ Cheap flights from Detroit to St. Louis (DTT - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — STL
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to St. Louis
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Best
Last-minute
One-way
Cheapest flights from Detroit to St. LouisExplore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:35 pm -
1 stop23h 39m
Fri 11/137:59 pm -
1 stop26h 52m
Deal found 10/7![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:25 am -
1 stop12h 17m
Wed 11/116:34 pm -
1 stop5h 10m
Deal found 10/5![Frontier logo]()
$175
This Expedia deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:07 pm -
1 stop27h 09m
Thu 11/1212:14 pm -
1 stop8h 29m
Deal found 10/8![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:28 pm -
1 stop13h 51m
Mon 11/212:14 pm -
1 stop20h 05m
Deal found 10/8![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:36 pm -
1 stop14h 41m
Mon 12/1412:02 pm -
1 stop26h 21m
Deal found 10/7![Frontier logo]()
$211
This Expedia deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
1 stop13h 14m
Mon 11/27:59 pm -
1 stop26h 52m
Deal found 10/6![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:25 am -
2 stops17h 51m
Mon 11/166:34 pm -
1 stop16h 09m
Deal found 10/6![Frontier logo]()
$214
This Priceline deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:49 pm -
1 stop6h 27m
Fri 10/3012:14 pm -
1 stop8h 29m
Deal found 10/6![Frontier logo]()
$219
This Priceline deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:02 pm -
1 stop11h 14m
Mon 11/912:14 pm -
1 stop8h 29m
Deal found 10/5![Frontier logo]()
$220
Best flights from Detroit to St. LouisDiscover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:20 pm -
Nonstop1h 50m
Tue 11/1010:15 am -
Nonstop1h 25m
Deal found 10/5![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:40 am -
Nonstop1h 45m
Tue 11/176:00 pm -
Nonstop1h 36m
Deal found 10/8![Delta logo]()
$290
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:15 pm -
Nonstop1h 45m
Wed 11/1110:15 am -
Nonstop1h 25m
Deal found 10/5![Southwest logo]()
$253
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:20 pm -
Nonstop1h 50m
Thu 12/32:25 pm -
1 stop5h 05m
Deal found 10/7![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:45 pm -
Nonstop1h 47m
Sat 12/124:38 pm -
Nonstop1h 37m
Deal found 10/6![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:10 am -
Nonstop1h 35m
Mon 11/21:05 pm -
1 stop3h 10m
Deal found 10/8![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:35 am -
2 stops8h 45m
Thu 11/124:30 pm -
2 stops6h 25m
Deal found 10/8![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:45 pm -
1 stop5h 15m
Tue 11/36:20 am -
2 stops7h 55m
Deal found 10/7![Southwest logo]()
$322
Last-minute flights from Detroit to St. LouisDiscover last-minute flight deals from Detroit to St. Louis. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to St. Louis. Data last updated October 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:35 pm -
1 stop19h 48m
Fri 10/307:59 pm -
1 stop18h 35m
Deal found 10/7![Frontier logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:28 pm -
1 stop13h 51m
Mon 11/212:14 pm -
1 stop20h 05m
Deal found 10/8![Frontier logo]()
$183
This Priceline deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:49 pm -
1 stop6h 27m
Fri 10/3012:14 pm -
1 stop8h 29m
Deal found 10/6![Frontier logo]()
$219
This Expedia deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
1 stop13h 14m
Mon 11/27:59 pm -
1 stop26h 52m
Deal found 10/6![Frontier logo]()
$213
This Priceline deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:02 pm -
1 stop11h 14m
Mon 11/912:14 pm -
1 stop8h 29m
Deal found 10/5![Frontier logo]()
$220
This Expedia deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:07 pm -
1 stop27h 09m
Thu 11/1212:14 pm -
1 stop8h 29m
Deal found 10/8![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:35 pm -
1 stop23h 39m
Fri 11/137:59 pm -
1 stop26h 52m
Deal found 10/7![Frontier logo]()
$174
This Frontier deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
1 stop13h 14m
Mon 11/912:14 pm -
1 stop8h 29m
Deal found 10/7![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:25 am -
1 stop12h 17m
Wed 11/116:34 pm -
1 stop5h 10m
Deal found 10/5![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:25 am -
2 stops17h 51m
Mon 11/166:34 pm -
1 stop16h 09m
Deal found 10/6![Frontier logo]()
$214
One-way flights from Detroit to St. LouisSearch for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:37 pm -
1 stop16h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:40 pm -
2 stops30h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:11 pm -
2 stops44h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Frontier logo]()
$96
This Trip.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:55 pm -
1 stop27h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:33 am -
1 stop28h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Frontier logo]()
$99
This Priceline deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:35 pm -
1 stop7h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:07 am -
2 stops32h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Frontier logo]()
$107
This CheapOair deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:35 pm -
1 stop23h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Frontier logo]()
$108
Find flight deals from Detroit to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $174 (Kiwi.com) |
One-way from | $89 (Kiwi.com) |
Popular in | January |
Cheapest in | June |
Average price | $405 |
Good round-trip deal | $308 or less |
Good one-way deal | $205 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Detroit to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Tue 10/27
12:07 pm-5:40 pm
2 stops30h 33m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$118
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Tue 11/10
7:45 pm-8:29 pm
Nonstop1h 44m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$123
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Sat 10/31
2:57 pm-3:37 pm
Nonstop1h 40m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Wed 11/4
8:10 pm-8:51 pm
Nonstop1h 41m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Mon 11/9
7:45 pm-8:29 pm
Nonstop1h 44m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Wed 1/6
4:55 pm-9:49 pm
1 stop5h 54m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$133
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Wed 11/4
5:30 am-12:40 pm
2 stops8h 10m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$138
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Thu 12/31
7:55 pm-8:43 pm
Nonstop1h 48m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$156
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 1/1
7:00 am-10:35 am
1 stop4h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$166
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 11/6
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$168
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Detroit to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.
DTT-STL
DTW-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to St. Louis
DTT-STL
DTW-STL
What is the cheapest month to book a flight from Detroit to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Detroit to St. Louis (average of $307). Flying from Detroit to St. Louis in February is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to STL?
Find hourly flight availability from Detroit to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 8, 2026.
When flying from Detroit to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 19% versus a flight in the morning.
Weekly flight availability from Detroit to St. Louis
Explore weekly flight availability from Detroit to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 8, 2026.
The most flights from DTT to STL are scheduled on a Wednesday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).
How far ahead should I book a flight from Detroit to St. Louis?
The price you pay for your flight from Detroit to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Detroit to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Detroit to St. Louis. Price data was last updated on October 3, 2026.
Travelers seeking maximum savings on their Detroit to St. Louis flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 8, 2026.
See what other customers who have flown with Southwest,Delta, andFrontier from Detroit to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Chesterfield
Maryland Heights
Collinsville
Edwardsville
Glencoe
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Alternative routes for Detroit to St. Louis
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Detroit and St. Louis flights
Browse other Detroit and St. Louis flight options. Last updated on October 8, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Top 3 airlines flying from Detroit to St. Louis
Discover the top 3 airlines that operate flights from Detroit to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$177 | Average$378 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$181 | Average$348 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$215 | Average$360 | FlexibilityNo cancel fee | On-time63% |