
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $167 (Southwest) |
One-way from | $84 (Southwest) |
Popular in | February |
Cheapest in | January |
Average price | $300 |
Good round-trip deal | $330 or less |
Good one-way deal | $194 or less |
Fly from
Fly to
Route
Depart
Return
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Mon 9/28
6:55 am-7:45 am
Nonstop1h 50m
Lambert-St Louis
Wed 9/30
11:10 am-1:40 pm
Nonstop1h 30m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 9/18
5:00 pm-10:00 pm
1 stop6h 00m
Lambert-St Louis
Sat 9/19
7:50 am-5:45 pm
2 stops8h 55m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 10/2
8:25 pm-9:00 pm
Nonstop1h 35m
Lambert-St Louis
Mon 10/5
7:50 pm-10:20 pm
Nonstop1h 30m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Thu 11/12
8:05 pm-8:51 pm
Nonstop1h 46m
Lambert-St Louis
Tue 11/17
7:18 pm-12:59 am
1 stop4h 41m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Thu 9/10
7:30 pm-10:10 pm
1 stop3h 40m
Lambert-St Louis
Sat 9/12
10:15 am-12:45 pm
Nonstop1h 30m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Thu 9/17
2:40 pm-3:10 pm
Nonstop1h 30m
Lambert-St Louis
Thu 10/1
11:40 am-4:20 pm
1 stop3h 40m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Thu 9/24
6:55 am-7:45 am
Nonstop1h 50m
Lambert-St Louis
Fri 9/25
2:45 pm-10:20 pm
2 stops6h 35m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Fri 11/13
7:58 pm-11:23 pm
1 stop4h 25m
Lambert-St Louis
Tue 11/17
5:30 pm-10:55 pm
1 stop4h 25m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Sat 9/12
7:05 am-10:34 am
1 stop4h 29m
Lambert-St Louis
Sun 9/13
6:40 am-9:13 am
Nonstop1h 33m
DetroitSt. Louis
DTW Detroit Metropolitan Wayne County - STL Lambert-St Louis
DTWSTL
Detroit Metropolitan Wayne County
Tue 9/22
6:25 am-7:00 am
Nonstop1h 35m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
Everything you need to know about your flight from Detroit to St. Louis
Crew
Comfort
Overall
Boarding
Entertainment
Food
Reviews
Libby,Jun 2026
TUS - LAS
Crew
Comfort
Overall
Boarding
Entertainment
Food
Reviews
Libby,Jun 2026
TUS - LAS
Crew
Comfort
Overall
Boarding
Entertainment
Food
Reviews
Libby,Jun 2026
TUS - LAS
Crew
Comfort
Overall
Boarding
Entertainment
Food
Reviews
Libby,Jun 2026
TUS - LAS
Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$310 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$177 | Average$373 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$205 | Average$350 | FlexibilityNo cancel fee | On-time63% |