$73+ Cheap flights from Detroit (DTT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — MCI
Aug 19 — Aug 261
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Detroit to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to MissouriExplore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:56 pm
DTW
- STL
1 stop19h 01m
Frontier
Mon 8/104:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 7/15![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/203:34 pm
DTW
- STL
1 stop19h 06m
Frontier
Sat 9/2610:35 am
STL
- DTW
1 stop13h 07m
Frontier
Deal found 7/18![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:10 am
DTW
- STL
1 stop12h 27m
Frontier
Thu 8/206:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/16![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
DTW
- STL
1 stop12h 22m
Frontier
Sun 8/236:17 pm
STL
- DTW
1 stop18h 22m
Frontier
Deal found 7/19![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 am
DTW
- STL
1 stop27h 47m
Frontier
Fri 8/144:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 7/18![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:10 am
DTW
- STL
1 stop27h 47m
Frontier
Fri 8/144:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 7/16![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:50 am
DTW
- STL
1 stop27h 50m
Frontier
Sun 9/1310:35 am
STL
- DTW
1 stop13h 07m
Frontier
Deal found 7/16![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:34 pm
DTW
- STL
1 stop19h 06m
Frontier
Wed 9/1610:35 am
STL
- DTW
1 stop13h 07m
Frontier
Deal found 7/16![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/246:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/16![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 am
DTW
- STL
1 stop27h 47m
Frontier
Tue 8/116:34 pm
STL
- DTW
1 stop20h 54m
Frontier
Deal found 7/17![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 am
DTW
- STL
1 stop27h 47m
Frontier
Thu 8/136:34 pm
STL
- DTW
1 stop29h 06m
Frontier
Deal found 7/16![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:10 am
DTW
- MCI
1 stop12h 00m
Frontier
Mon 8/176:17 pm
MCI
- DTW
1 stop14h 03m
Frontier
Deal found 7/19![Frontier logo]()
$164
Best flights from Detroit to MissouriDiscover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 20, 2026.
Discover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 20, 2026.
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:00 am
DTW
- STL
Nonstop1h 37m
Delta
Mon 8/106:25 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 7/15![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:20 pm
DTW
- STL
1 stop4h 00m
Southwest
Thu 8/206:50 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 7/16![Southwest logo]()
$227
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:20 am
DTW
- MCI
1 stop7h 02m
Frontier
Sun 10/42:17 pm
MCI
- DTW
1 stop9h 07m
Frontier
Deal found 7/19![Frontier logo]()
$278
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:05 pm
DTW
- STL
2 stops8h 55m
United Airlines
Wed 8/129:30 am
STL
- DTW
1 stop6h 30m
United Airlines
Deal found 7/15![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
DTW
- STL
2 stops8h 30m
Southwest
Sun 9/65:50 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 7/19![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:35 pm
DTW
- STL
Nonstop1h 39m
Delta
Sun 8/236:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 7/15![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:50 am
DTW
- COU
1 stop7h 00m
United Airlines
Sat 8/153:12 pm
COU
- DTW
1 stop6h 13m
United Airlines
Deal found 7/15![United Airlines logo]()
$313
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:40 am
DTW
- MCI
1 stop6h 20m
Frontier
Fri 8/146:17 pm
MCI
- DTW
1 stop5h 23m
Frontier
Deal found 7/19![Frontier logo]()
$325
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:40 pm
DTW
- STL
Nonstop1h 30m
Southwest
Sun 9/134:20 pm
STL
- DTW
1 stop4h 10m
Southwest
Deal found 7/16![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:50 am
DTW
- STL
Nonstop1h 39m
Delta
Sun 9/1310:29 am
STL
- DTW
Nonstop1h 33m
Delta
Deal found 7/17![Delta logo]()
$300
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:35 pm
DTW
- JLN
2 stops12h 09m
United Airlines
Sun 8/231:53 pm
JLN
- DTW
1 stop7h 45m
United Airlines
Deal found 7/17![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:30 pm
DTW
- STL
Nonstop1h 36m
Delta
Sat 9/264:10 pm
STL
- DTW
Nonstop1h 32m
Delta
Deal found 7/18![Delta logo]()
$300
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:35 am
DTW
- STL
Nonstop1h 35m
Southwest
Mon 8/106:05 am
STL
- DTW
1 stop3h 25m
Southwest
Deal found 7/19![Southwest logo]()
$310
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:30 am
DTW
- COU
1 stop5h 00m
United Airlines
Sun 8/306:15 am
COU
- DTW
1 stop4h 12m
United Airlines
Deal found 7/15![United Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:25 am
DTW
- SGF
1 stop7h 12m
Delta
Sat 10/106:06 am
SGF
- DTW
1 stop6h 01m
Delta
Deal found 7/19![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DTW
- STL
2 stops7h 15m
Southwest
Sun 8/236:00 am
STL
- DTW
2 stops7h 35m
Southwest
Deal found 7/19![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:15 am
DTW
- STL
1 stop3h 42m
United Airlines
Sat 8/227:25 am
STL
- DTW
2 stops10h 33m
United Airlines
Deal found 7/17![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:25 am
DTW
- SGF
1 stop7h 09m
Delta
Mon 9/285:34 pm
SGF
- DTW
1 stop6h 20m
Delta
Deal found 7/16![Delta logo]()
$378
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:30 am
DTW
- JLN
1 stop5h 39m
United Airlines
Wed 10/287:02 am
JLN
- DTW
1 stop7h 29m
United Airlines
Deal found 7/18![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:35 am
DTW
- MCI
1 stop4h 10m
Southwest
Tue 9/110:20 am
MCI
- DTW
1 stop3h 40m
Southwest
Deal found 7/17![Southwest logo]()
$389
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:41 am
DTW
- MCI
Nonstop2h 04m
Delta
Sun 8/165:46 pm
MCI
- DTW
Nonstop1h 57m
Delta
Deal found 7/15![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:35 pm
DTW
- SGF
1 stop6h 27m
United Airlines
Sun 8/236:37 pm
SGF
- DTW
1 stop4h 22m
United Airlines
Deal found 7/16![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:20 pm
DTW
- MCI
Nonstop1h 58m
Delta
Tue 10/62:15 pm
MCI
- DTW
Nonstop1h 54m
Delta
Deal found 7/18![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:22 pm
DTW
- COU
1 stop5h 11m
United Airlines
Sun 7/263:25 pm
COU
- DTW
1 stop3h 57m
United Airlines
Deal found 7/20![United Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:50 pm
DTW
- MCI
1 stop4h 37m
Delta
Sun 8/236:20 am
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 7/16![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:30 am
DTW
- COU
1 stop5h 43m
United Airlines
Mon 8/33:25 pm
COU
- DTW
1 stop5h 54m
United Airlines
Deal found 7/17![United Airlines logo]()
$438
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:50 pm
DTW
- MCI
Nonstop2h 00m
Delta
Tue 8/182:13 pm
MCI
- DTW
Nonstop1h 57m
Delta
Deal found 7/15![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:15 am
DTW
- SGF
2 stops13h 27m
United Airlines
Sat 10/106:25 pm
SGF
- DTW
1 stop4h 34m
United Airlines
Deal found 7/18![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:41 am
DTW
- MCI
Nonstop2h 04m
Delta
Sun 8/235:40 pm
MCI
- DTW
1 stop4h 01m
Delta
Deal found 7/19![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:35 pm
DTW
- COU
2 stops9h 58m
United Airlines
Sun 8/910:49 am
COU
- DTW
1 stop6h 49m
United Airlines
Deal found 7/19![United Airlines logo]()
$444
Last-minute flights from Detroit to MissouriDiscover last-minute flight deals from Detroit to Missouri. Data last updated July 20, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Missouri. Data last updated July 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:56 pm
DTW
- STL
1 stop19h 01m
Frontier
Mon 8/104:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 7/15![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:10 am
DTW
- STL
1 stop27h 47m
Frontier
Fri 8/144:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 7/16![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 am
DTW
- STL
1 stop27h 47m
Frontier
Fri 8/144:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 7/18![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 am
DTW
- STL
1 stop27h 47m
Frontier
Tue 8/116:34 pm
STL
- DTW
1 stop20h 54m
Frontier
Deal found 7/17![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 am
DTW
- STL
1 stop27h 47m
Frontier
Thu 8/136:34 pm
STL
- DTW
1 stop29h 06m
Frontier
Deal found 7/16![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:56 pm
DTW
- MCI
1 stop27h 14m
Frontier
Mon 8/176:17 pm
MCI
- DTW
1 stop14h 03m
Frontier
Deal found 7/18![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:10 am
DTW
- STL
1 stop12h 27m
Frontier
Thu 8/206:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/16![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:10 am
DTW
- MCI
1 stop12h 00m
Frontier
Mon 8/176:17 pm
MCI
- DTW
1 stop14h 03m
Frontier
Deal found 7/19![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:10 am
DTW
- MCI
1 stop12h 00m
Frontier
Mon 8/2411:26 am
MCI
- DTW
1 stop12h 38m
Frontier
Deal found 7/18![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
DTW
- STL
1 stop12h 22m
Frontier
Sun 8/236:17 pm
STL
- DTW
1 stop18h 22m
Frontier
Deal found 7/19![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/246:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/16![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/316:17 pm
STL
- DTW
2 stops17h 27m
Frontier
Deal found 7/18![Frontier logo]()
$164
One-way flights from Detroit to MissouriSearch for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated July 20, 2026.
Search for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated July 20, 2026.
This Trip.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:00 am
DTW
- STL
1 stop12h 22m
Frontier
Deal found 7/15![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
DTW
- STL
1 stop12h 22m
Frontier
Deal found 7/15![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:34 pm
DTW
- STL
1 stop19h 06m
Frontier
Deal found 7/19![Frontier logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:40 pm
DTW
- STL
1 stop23h 42m
Frontier
Deal found 7/15![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:34 pm
DTW
- STL
1 stop19h 06m
Frontier
Deal found 7/15![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:38 pm
DTW
- STL
1 stop19h 02m
Frontier
Deal found 7/16![Frontier logo]()
$78
This Trip.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DTW
- STL
1 stop12h 22m
Frontier
Deal found 7/17![Frontier logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:56 pm
DTW
- STL
1 stop19h 01m
Frontier
Deal found 7/17![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:34 pm
DTW
- STL
1 stop19h 06m
Frontier
Deal found 7/16![Frontier logo]()
$82
This Trip.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:50 am
DTW
- MCI
1 stop11h 26m
Frontier
Deal found 7/18![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:38 pm
DTW
- STL
1 stop19h 02m
Frontier
Deal found 7/16![Frontier logo]()
$83
This Trip.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
DTW
- MCI
1 stop11h 05m
Frontier
Deal found 7/15![Frontier logo]()
$83
Find flight deals from Detroit to Missouri
Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated July 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $141 (Kiwi.com) |
One-way from | $73 (Trip.com) |
Popular in | April |
Cheapest in | August |
Average price | $361 |
Good round-trip deal | $348 or less |
Good one-way deal | $184 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
Use the filters below to find and compare flights from Detroit to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 8/6
9:00 am-9:37 am
Nonstop1h 37m
Lambert-St Louis
Mon 8/10
6:25 pm-9:00 pm
Nonstop1h 35m
$217
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 8/13
1:20 pm-4:20 pm
1 stop4h 00m
Lambert-St Louis
Thu 8/20
6:50 pm-9:20 pm
Nonstop1h 30m
$227
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 9/5
6:00 am-1:30 pm
2 stops8h 30m
Lambert-St Louis
Sun 9/6
5:50 pm-8:20 pm
Nonstop1h 30m
$232
DetroitKansas City
DTW - MCI
DTWMCI
Detroit Metropolitan Wayne County
Fri 10/2
7:20 am-1:22 pm
1 stop7h 02m
Kansas City
Sun 10/4
2:17 pm-12:24 am
1 stop9h 07m
$278
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 8/15
4:35 pm-5:14 pm
Nonstop1h 39m
Lambert-St Louis
Sun 8/23
6:30 am-9:04 am
Nonstop1h 34m
$289
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 9/10
2:40 pm-3:10 pm
Nonstop1h 30m
Lambert-St Louis
Sun 9/13
4:20 pm-9:30 pm
1 stop4h 10m
$299
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 9/10
8:50 am-9:29 am
Nonstop1h 39m
Lambert-St Louis
Sun 9/13
10:29 am-1:02 pm
Nonstop1h 33m
$300
Quickest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sun 9/20
12:30 pm-1:06 pm
Nonstop1h 36m
Lambert-St Louis
Sat 9/26
4:10 pm-6:42 pm
Nonstop1h 32m
$300
DetroitSpringfield
DTW - SGF
DTWSGF
Detroit Metropolitan Wayne County
Wed 10/7
8:25 am-2:37 pm
1 stop7h 12m
Springfield-Branson
Sat 10/10
6:06 am-1:07 pm
1 stop6h 01m
$309
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sun 8/9
6:35 am-7:10 am
Nonstop1h 35m
Lambert-St Louis
Mon 8/10
6:05 am-10:30 am
1 stop3h 25m
$310
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
DTW-STL
DTW-SGF
DTW-COU
DTW-MCI
DTW-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Missouri
DTT-USMO
DTW-STL
DTW-SGF
DTW-COU
DTW-MCI
What is the cheapest month to book a flight from Detroit to Missouri?
Currently, August is the cheapest month in which you can book a flight from Detroit to Missouri (average of $269). Flying from Detroit to Missouri in February is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to MO?
Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 20, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit to Missouri in the afternoon. If you’re flexible enough to do this you can expect to save up to 5% on your trip compared to booking a flight in the morning.
Weekly flight availability from Detroit to Missouri
Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 20, 2026.
The most flights from DTT to USMO are scheduled on a Sunday (15 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (11 on average).
How much does it cost to fly round-trip from Detroit to Missouri?
How far ahead should I book a flight from Detroit to Missouri?
The price you pay for your flight from Detroit to Missouri may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Detroit to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Detroit to Missouri. Price data was last updated on July 18, 2026.
Travelers seeking maximum savings on their Detroit to Missouri flight should consider departing on Tuesday at noon when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 20, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Detroit to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Detroit to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Missouri by cabin class
Find flights from Detroit to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Missouri flights
Browse other Detroit and Missouri flight options. Last updated on July 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to Missouri flights
Consider these flights traveling from Detroit to Missouri.
Top 5 airlines flying from Detroit to Missouri
Discover the top 5 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$117 | Average$246 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$192 | Average$388 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$253 | Average$386 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$406 | FlexibilityNo cancel fee | On-time71% |