$76+ Cheap flights from Detroit (DTT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — MCI
Jun 25 — Jul 21
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Missouri with Cheapflights
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Cheapest flights from Detroit to MissouriExplore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:56 pm
DTW
- STL
1 stop19h 01m
Frontier
Mon 7/134:57 pm
STL
- DTW
1 stop6h 43m
Frontier
Deal found 5/21![Frontier logo]()
$166
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Sat 6/207:05 pm
STL
- DTW
1 stop3h 52m
United Airlines
Deal found 5/25![United Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:50 am
DTW
- STL
Nonstop1h 42m
Delta
Tue 6/236:10 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/25![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:50 am
DTW
- STL
2 stops13h 40m
Southwest
Mon 7/135:40 am
STL
- DTW
1 stop3h 25m
Southwest
Deal found 5/25![Southwest logo]()
$188
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Sat 6/204:40 pm
STL
- DTW
1 stop4h 45m
Southwest
Deal found 5/25![Southwest logo]()
$193
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Tue 6/305:33 pm
STL
- DTW
1 stop3h 46m
United Airlines
Deal found 5/24![United Airlines logo]()
$198
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 pm
DTW
- STL
Nonstop1h 35m
Southwest
Sat 7/410:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/24![Southwest logo]()
$209
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:50 am
DTW
- STL
1 stop4h 21m
United Airlines
Mon 6/225:29 pm
STL
- DTW
1 stop5h 28m
United Airlines
Deal found 5/26![United Airlines logo]()
$212
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:00 pm
DTW
- STL
Nonstop1h 39m
Delta
Thu 7/96:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/21![Delta logo]()
$213
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:28 pm
DTW
- STL
Nonstop1h 37m
Delta
Mon 7/136:04 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/22![Delta logo]()
$217
This Frontier deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Wed 7/16:16 pm
MCI
- DTW
1 stop5h 28m
Frontier
Deal found 5/25![Frontier logo]()
$258
This Frontier deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Sat 6/201:45 pm
MCI
- DTW
1 stop9h 14m
Frontier
Deal found 5/22![Frontier logo]()
$263
Best flights from Detroit to MissouriDiscover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 26, 2026.
Discover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 26, 2026.
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:45 pm
DTW
- STL
Nonstop1h 39m
Delta
Mon 7/206:09 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/26![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Wed 7/227:40 pm
STL
- DTW
Nonstop1h 35m
Southwest
Deal found 5/25![Southwest logo]()
$209
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:58 am
DTW
- STL
1 stop5h 48m
United Airlines
Mon 8/35:33 pm
STL
- DTW
1 stop3h 46m
United Airlines
Deal found 5/26![United Airlines logo]()
$228
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:36 pm
DTW
- COU
2 stops8h 25m
American Airlines
Fri 7/105:19 pm
COU
- DTW
1 stop5h 22m
American Airlines
Deal found 5/21![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:00 am
DTW
- STL
Nonstop1h 37m
Delta
Sun 8/910:33 am
STL
- DTW
Nonstop1h 32m
Delta
Deal found 5/26![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:50 am
DTW
- STL
Nonstop1h 42m
Delta
Sun 6/286:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/24![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:50 am
DTW
- STL
Nonstop1h 41m
Delta
Mon 8/36:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/26![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:50 am
DTW
- STL
1 stop6h 00m
Southwest
Sun 7/54:40 pm
STL
- DTW
1 stop4h 20m
Southwest
Deal found 5/24![Southwest logo]()
$252
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Fri 6/195:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Deal found 5/22![United Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:20 pm
DTW
- STL
2 stops9h 30m
Southwest
Mon 8/37:10 pm
STL
- DTW
1 stop4h 00m
Southwest
Deal found 5/26![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:50 am
DTW
- STL
Nonstop1h 41m
Delta
Tue 8/46:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/22![Delta logo]()
$217
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:30 am
DTW
- COU
1 stop4h 03m
United Airlines
Sun 10/186:15 am
COU
- DTW
1 stop4h 09m
United Airlines
Deal found 5/25![United Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:55 am
DTW
- STL
1 stop6h 10m
Southwest
Tue 7/143:15 pm
STL
- DTW
2 stops6h 40m
Southwest
Deal found 5/24![Southwest logo]()
$283
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:20 pm
DTW
- SGF
1 stop6h 07m
United Airlines
Mon 6/226:35 pm
SGF
- DTW
1 stop4h 22m
United Airlines
Deal found 5/26![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:25 am
DTW
- SGF
1 stop6h 23m
United Airlines
Sun 9/206:37 pm
SGF
- DTW
1 stop4h 22m
United Airlines
Deal found 5/21![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:34 am
DTW
- COU
1 stop3h 42m
United Airlines
Wed 9/210:55 am
COU
- DTW
1 stop5h 05m
United Airlines
Deal found 5/21![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:50 am
DTW
- MCI
2 stops7h 10m
Southwest
Sun 6/285:05 am
MCI
- DTW
1 stop4h 40m
Southwest
Deal found 5/24![Southwest logo]()
$424
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:22 pm
DTW
- MCI
Nonstop2h 01m
Delta
Sun 6/286:25 am
MCI
- DTW
Nonstop2h 00m
Delta
Deal found 5/22![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:07 pm
DTW
- JLN
1 stop5h 39m
United Airlines
Wed 9/21:53 pm
JLN
- DTW
1 stop7h 46m
United Airlines
Deal found 5/24![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/263:55 pm
DTW
- MCI
Nonstop2h 02m
Delta
Sun 6/286:25 am
MCI
- DTW
Nonstop2h 00m
Delta
Deal found 5/21![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:50 am
DTW
- JLN
1 stop5h 32m
United Airlines
Fri 7/101:57 pm
JLN
- DTW
2 stops8h 57m
United Airlines
Deal found 5/24![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:40 am
DTW
- MCI
Nonstop2h 04m
Delta
Sat 7/256:23 am
MCI
- DTW
1 stop4h 19m
Delta
Deal found 5/25![Delta logo]()
$409
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:30 pm
DTW
- MCI
1 stop3h 45m
Southwest
Tue 6/92:10 pm
MCI
- DTW
2 stops7h 00m
Southwest
Deal found 5/25![Southwest logo]()
$532
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:01 am
DTW
- MCI
1 stop5h 45m
Delta
Sun 8/26:25 am
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 5/23![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:25 am
DTW
- SGF
1 stop6h 23m
United Airlines
Wed 9/235:30 am
SGF
- DTW
2 stops8h 59m
United Airlines
Deal found 5/21![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:40 am
DTW
- MCI
2 stops7h 25m
Southwest
Sun 6/142:30 pm
MCI
- DTW
2 stops7h 40m
Southwest
Deal found 5/25![Southwest logo]()
$538
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:15 am
DTW
- MCI
1 stop5h 11m
Delta
Sat 8/810:31 am
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 5/22![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:30 am
DTW
- SGF
2 stops8h 26m
United Airlines
Tue 10/276:15 pm
SGF
- DTW
1 stop4h 37m
United Airlines
Deal found 5/25![United Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:35 pm
DTW
- SGF
2 stops9h 12m
United Airlines
Mon 8/316:37 pm
SGF
- DTW
1 stop4h 22m
United Airlines
Deal found 5/24![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:35 am
DTW
- SGF
2 stops13h 38m
Delta
Sat 7/46:00 am
SGF
- DTW
1 stop5h 04m
Delta
Deal found 5/25![Delta logo]()
$476
Last-minute flights from Detroit to MissouriDiscover last-minute flight deals from Detroit to Missouri. Data last updated May 26, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Missouri. Data last updated May 26, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Sat 6/201:45 pm
MCI
- DTW
1 stop9h 14m
Frontier
Deal found 5/22![Frontier logo]()
$263
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Sat 6/207:05 pm
STL
- DTW
1 stop3h 52m
United Airlines
Deal found 5/25![United Airlines logo]()
$172
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Sat 6/204:40 pm
STL
- DTW
1 stop4h 45m
Southwest
Deal found 5/25![Southwest logo]()
$193
This Frontier deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 am
DTW
- STL
1 stop12h 00m
Frontier
Wed 6/175:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Deal found 5/25![Frontier logo]()
$230
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:50 am
DTW
- STL
Nonstop1h 42m
Delta
Tue 6/236:10 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/25![Delta logo]()
$177
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:50 am
DTW
- STL
1 stop4h 21m
United Airlines
Mon 6/225:29 pm
STL
- DTW
1 stop5h 28m
United Airlines
Deal found 5/26![United Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Tue 6/305:33 pm
STL
- DTW
1 stop3h 46m
United Airlines
Deal found 5/24![United Airlines logo]()
$198
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:00 pm
DTW
- STL
Nonstop1h 39m
Delta
Thu 7/96:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/21![Delta logo]()
$213
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:50 pm
DTW
- STL
1 stop3h 35m
Southwest
Tue 6/307:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/24![Southwest logo]()
$219
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:58 pm
DTW
- STL
1 stop4h 46m
American Airlines
Tue 6/3012:45 pm
STL
- DTW
1 stop5h 33m
American Airlines
Deal found 5/24![American Airlines logo]()
$228
This Frontier deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Wed 7/16:16 pm
MCI
- DTW
1 stop5h 28m
Frontier
Deal found 5/25![Frontier logo]()
$258
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 pm
DTW
- STL
Nonstop1h 35m
Southwest
Sat 7/410:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/24![Southwest logo]()
$209
One-way flights from Detroit to MissouriSearch for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated May 26, 2026.
Search for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated May 26, 2026.
This Trip.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:10 am
DTW
- MCI
1 stop12h 00m
Frontier
Deal found 5/21![Frontier logo]()
$76
This Trip.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:10 am
DTW
- MCI
1 stop12h 00m
Frontier
Deal found 5/21![Frontier logo]()
$77
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:15 pm
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/25![Southwest logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:38 pm
DTW
- STL
1 stop16h 14m
Frontier
Deal found 5/21![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:02 pm
DTW
- MCI
1 stop28h 19m
Frontier
Deal found 5/21![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:38 pm
DTW
- STL
1 stop24h 52m
Frontier
Deal found 5/21![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:56 pm
DTW
- MCI
1 stop27h 14m
Frontier
Deal found 5/21![Frontier logo]()
$82
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Deal found 5/25![United Airlines logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:56 pm
DTW
- STL
1 stop19h 01m
Frontier
Deal found 5/21![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:56 pm
DTW
- STL
1 stop19h 01m
Frontier
Deal found 5/21![Frontier logo]()
$88
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:22 pm
DTW
- STL
1 stop5h 07m
United Airlines
Deal found 5/26![United Airlines logo]()
$89
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:30 am
DTW
- STL
2 stops7h 35m
Southwest
Deal found 5/25![Southwest logo]()
$94
Find flight deals from Detroit to Missouri
Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated May 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $166 (Kiwi.com) |
One-way from | $76 (Trip.com) |
Popular in | April |
Cheapest in | August |
Average price | $327 |
Good round-trip deal | $361 or less |
Good one-way deal | $234 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Detroit to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 7/17
4:45 pm-5:24 pm
Nonstop1h 39m
Lambert-St Louis
Mon 7/20
6:09 pm-8:44 pm
Nonstop1h 35m
$177
Quickest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 8/6
9:00 am-9:37 am
Nonstop1h 37m
Lambert-St Louis
Sun 8/9
10:33 am-1:05 pm
Nonstop1h 32m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 6/24
8:50 am-9:32 am
Nonstop1h 42m
Lambert-St Louis
Sun 6/28
6:30 am-9:04 am
Nonstop1h 34m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 8/1
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Mon 8/3
6:30 am-9:04 am
Nonstop1h 34m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 7/22
7:05 am-7:40 am
Nonstop1h 35m
Lambert-St Louis
Wed 7/22
7:40 pm-10:15 pm
Nonstop1h 35m
$209
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 7/29
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Tue 8/4
6:30 am-9:04 am
Nonstop1h 34m
$217
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 8/1
10:58 am-3:46 pm
1 stop5h 48m
Lambert-St Louis
Mon 8/3
5:33 pm-10:19 pm
1 stop3h 46m
$228
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 7/3
5:50 am-10:50 am
1 stop6h 00m
Lambert-St Louis
Sun 7/5
4:40 pm-10:00 pm
1 stop4h 20m
$252
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 8/1
1:20 pm-9:50 pm
2 stops9h 30m
Lambert-St Louis
Mon 8/3
7:10 pm-12:10 am
1 stop4h 00m
$257
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 6/17
7:05 am-12:11 pm
1 stop6h 06m
Lambert-St Louis
Fri 6/19
5:29 pm-10:19 pm
1 stop3h 50m
$277
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
DTW-STL
DTW-COU
DTW-SGF
DTW-MCI
DTW-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Missouri
DTT-USMO
DTW-STL
DTW-COU
DTW-SGF
DTW-MCI
What is the cheapest month to book a flight from Detroit to Missouri?
Currently, August is the cheapest month in which you can book a flight from Detroit to Missouri (average of $27). Flying from Detroit to Missouri in April is currently the most expensive (average of $181). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to MO?
Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 26, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit to Missouri at noon. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the evening.
Weekly flight availability from Detroit to Missouri
Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 26, 2026.
The most flights from DTT to USMO are scheduled on a Monday (15 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (8 on average).
How much does it cost to fly round-trip from Detroit to Missouri?
How far ahead should I book a flight from Detroit to Missouri?
The price you pay for your flight from Detroit to Missouri may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Detroit to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Detroit to Missouri. Price data was last updated on May 23, 2026.
Travelers seeking maximum savings on their Detroit to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 26, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Detroit to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Spirit Airlines
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Missouri by cabin class
Find flights from Detroit to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Missouri flights
Browse other Detroit and Missouri flight options. Last updated on May 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to Missouri flights
Consider these flights traveling from Detroit to Missouri.
Top 6 airlines flying from Detroit to Missouri
Discover the top 6 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$149 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$227 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$149 | Average$379 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$253 | Average$389 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$292 | Average$406 | FlexibilityNo cancel fee | On-time71% |