How long is the flight from Buffalo to St. Louis?

There are many flights that can get you from Buffalo to St. Louis in 4h 36m. Fly via Southwest, American Airlines, or Delta to get the fastest option. There are 672 mi between Buffalo and St. Louis. This flight may include one or multiple stops.

What are the cheapest airlines flying from Buffalo to St. Louis round-trip?

Our cheapest airline available from Buffalo to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $164 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $243 and $296 round-trip. Delta is currently priced 53% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Buffalo to St. Louis one-way?

To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $95. Southwest flights start at $119 while deals on Delta start at $125 one-way.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Buffalo to St. Louis?

Consider Delta, American Airlines or Southwest when booking your flight. These represent the most popular airlines when flying from Buffalo to St. Louis.

Most accurate provider : When it comes to deals on Buffalo-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

Can I find deals for business class flights from Buffalo to St. Louis?

Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$98+ Flights from Buffalo to St. Louis

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Find cheap flights from Buffalo to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Buffalo to Lambert-St Louis are usually found in September or July, booked 29 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Sat 12/63:18 pmBUF - STL

1 stop18h 41mFrontier

Wed 12/173:30 pmSTL - BUF

1 stop20h 42mFrontier

Deal found 12/3

$224

Thu 12/182:07 pmBUF - STL

1 stop9h 26mFrontier

Mon 12/2210:40 amSTL - BUF

1 stop9h 28mFrontier

Deal found 12/3

$234

Wed 12/176:00 amBUF - STL

1 stop7h 57mDelta

Sun 12/215:59 pmSTL - BUF

1 stop4h 29mDelta

Deal found 12/2

$352

Tue 12/231:47 pmBUF - STL

1 stop9h 46mFrontier

Mon 12/294:27 pmSTL - BUF

1 stop19h 25mFrontier

Deal found 12/3

$397

Fri 12/199:42 amBUF - STL

1 stop13h 51mMultiple Airlines

Tue 12/2310:48 amSTL - BUF

2 stops32h 52mMultiple Airlines

Deal found 12/4

$399

Thu 12/185:50 pmBUF - STL

1 stop3h 57mDelta

Sun 1/45:13 pmSTL - BUF

1 stop5h 37mDelta

Deal found 12/2

$407

Fri 12/199:42 amBUF - STL

1 stop11h 00mFrontier

Tue 12/234:27 pmSTL - BUF

1 stop27h 13mFrontier

Deal found 12/4

$416

Tue 12/2312:40 pmBUF - STL

2 stops10h 20mSouthwest

Mon 12/292:15 pmSTL - BUF

1 stop7h 10mSouthwest

Deal found 12/3

$438

Fri 12/195:35 pmBUF - STL

1 stop6h 08mUnited Airlines

Sun 12/213:10 pmSTL - BUF

1 stop4h 44mUnited Airlines

Deal found 12/1

$447

Fri 12/196:55 amBUF - STL

2 stops8h 05mSouthwest

Sun 12/214:50 pmSTL - BUF

1 stop5h 45mSouthwest

Deal found 12/1

$452

Sat 12/275:50 amBUF - STL

1 stop4h 10mSouthwest

Mon 12/292:15 pmSTL - BUF

1 stop7h 10mSouthwest

Deal found 12/2

$472

Wed 12/173:00 pmBUF - STL

2 stops9h 42mUnited Airlines

Sun 12/219:55 amSTL - BUF

1 stop5h 59mUnited Airlines

Deal found 12/2

$474

Best flights from Buffalo to St. Louis
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

Tue 1/136:20 amBUF - STL

1 stop5h 55mSouthwest

Wed 1/216:50 amSTL - BUF

1 stop4h 40mSouthwest

Deal found 12/1

$154

Tue 1/134:17 pmBUF - STL

2 stops7h 55mAmerican Airlines

Wed 1/216:44 pmSTL - BUF

1 stop4h 04mAmerican Airlines

Deal found 12/1

$164

Sun 1/186:03 amBUF - STL

1 stop4h 36mDelta

Thu 1/229:45 amSTL - BUF

1 stop6h 19mDelta

Deal found 12/1

$227

Fri 1/1612:15 pmBUF - STL

2 stops27h 33mFrontier

Fri 1/2311:18 amSTL - BUF

1 stop23h 16mFrontier

Deal found 12/2

$228

Sun 1/188:30 amBUF - STL

1 stop7h 00mUnited Airlines

Thu 1/228:05 amSTL - BUF

1 stop4h 19mUnited Airlines

Deal found 12/2

$296

Thu 12/182:07 pmBUF - STL

1 stop9h 26mFrontier

Mon 12/2210:40 amSTL - BUF

1 stop9h 28mFrontier

Deal found 12/3

$234

Wed 1/712:20 pmBUF - STL

2 stops7h 25mSouthwest

Thu 1/1512:05 pmSTL - BUF

2 stops8h 10mSouthwest

Deal found 12/2

$252

Sat 2/145:30 amBUF - STL

1 stop8h 01mAmerican Airlines

Thu 2/196:00 amSTL - BUF

1 stop5h 04mAmerican Airlines

Deal found 12/2

$310

Fri 1/28:50 amBUF - STL

2 stops9h 40mSouthwest

Tue 1/68:15 amSTL - BUF

1 stop5h 55mSouthwest

Deal found 12/2

$313

Last-minute flights from Buffalo to St. Louis
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated December 4, 2025 and is based on user searches.

Sat 12/63:18 pmBUF - STL

1 stop18h 41mFrontier

Wed 12/173:30 pmSTL - BUF

1 stop20h 42mFrontier

Deal found 12/3

$224

Thu 12/182:07 pmBUF - STL

1 stop9h 26mFrontier

Mon 12/2210:40 amSTL - BUF

1 stop9h 28mFrontier

Deal found 12/3

$234

Fri 1/26:10 amBUF - STL

1 stop4h 14mDelta

Tue 1/65:56 pmSTL - BUF

1 stop4h 01mDelta

Deal found 12/2

$282

Wed 1/75:27 pmBUF - STL

1 stop5h 24mAmerican Airlines

Thu 1/156:52 amSTL - BUF

1 stop4h 16mAmerican Airlines

Deal found 12/2

$177

Wed 1/712:20 pmBUF - STL

2 stops7h 25mSouthwest

Thu 1/1512:05 pmSTL - BUF

2 stops8h 10mSouthwest

Deal found 12/2

$252

Tue 1/136:20 amBUF - STL

1 stop5h 55mSouthwest

Wed 1/216:50 amSTL - BUF

1 stop4h 40mSouthwest

Deal found 12/1

$154

Tue 1/134:17 pmBUF - STL

2 stops7h 55mAmerican Airlines

Wed 1/216:44 pmSTL - BUF

1 stop4h 04mAmerican Airlines

Deal found 12/1

$164

Fri 1/1612:15 pmBUF - STL

1 stop19h 36mFrontier

Fri 1/235:42 pmSTL - BUF

1 stop16h 52mFrontier

Deal found 12/2

$208

Sun 1/186:03 amBUF - STL

1 stop4h 36mDelta

Thu 1/229:45 amSTL - BUF

1 stop6h 19mDelta

Deal found 12/1

$227

One-way flights from Buffalo to St. Louis
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 4, 2025.

Mon 3/26:45 amBUF - STL

1 stop5h 28mAmerican Airlines

Deal found 12/4

$98

Fri 12/1212:37 pmBUF - STL

1 stop10h 56mFrontier

Deal found 12/2

$112

Mon 3/29:57 amBUF - STL

2 stops49h 05mFrontier

Deal found 12/4

$114

Thu 12/182:07 pmBUF - STL

1 stop9h 26mFrontier

Deal found 12/2

$132

Sun 12/217:58 pmBUF - STL

1 stop13h 14mFrontier

Deal found 12/2

$157

Thu 1/158:30 amBUF - STL

1 stop4h 59mUnited Airlines

Deal found 12/3

$171

Thu 12/1112:35 pmBUF - STL

2 stops21h 24mFrontier

Deal found 12/2

$175

Mon 1/55:45 pmBUF - STL

1 stop6h 30mSouthwest

Deal found 12/1

$184

Mon 3/212:47 pmBUF - STL

3 stops46h 15mMultiple Airlines

Deal found 12/4

$188

Sun 12/217:58 pmBUF - STL

2 stops39h 58mMultiple Airlines

Deal found 12/2

$199

Fri 12/199:35 pmBUF - STL

2 stops37h 05mFrontier

Deal found 12/2

$202

Sat 12/207:05 pmBUF - STL

1 stop15h 35mFrontier

Deal found 12/2

$204

Find flight deals from Buffalo to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$154 (Southwest)
One-way from	$98 (American Airlines)
Popular in	December
Cheapest in	September
Average price	$406

Provider with most accurate pricing for Buffalo-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Buffalo-Lambert-St Louis flights.

Search Deals

From Buffalo to Lambert-St Louis

Search Deals

One-way flight from Buffalo to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($15 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 1/13

6:20 am-11:15 am

1 stop5h 55m

Lambert-St Louis

Wed 1/21

6:50 am-12:30 pm

1 stop4h 40m

$154

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 1/13

4:17 pm-11:12 pm

2 stops7h 55m

Lambert-St Louis

Wed 1/21

6:44 pm-11:48 pm

1 stop4h 04m

$164

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 1/18

6:03 am-9:39 am

1 stop4h 36m

Lambert-St Louis

Thu 1/22

9:45 am-5:04 pm

1 stop6h 19m

$227

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 1/16

12:15 pm-2:48 pm

2 stops27h 33m

Lambert-St Louis

Fri 1/23

11:18 am-11:34 am

1 stop23h 16m

$228

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 12/18

2:07 pm-10:33 pm

1 stop9h 26m

Lambert-St Louis

Mon 12/22

10:40 am-9:08 pm

1 stop9h 28m

$234

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 1/7

12:20 pm-6:45 pm

2 stops7h 25m

Lambert-St Louis

Thu 1/15

12:05 pm-9:15 pm

2 stops8h 10m

$252

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 1/18

8:30 am-2:30 pm

1 stop7h 00m

Lambert-St Louis

Thu 1/22

8:05 am-1:24 pm

1 stop4h 19m

$296

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 2/14

5:30 am-12:31 pm

1 stop8h 01m

Lambert-St Louis

Thu 2/19

6:00 am-12:04 pm

1 stop5h 04m

$310

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 1/2

8:50 am-5:30 pm

2 stops9h 40m

Lambert-St Louis

Tue 1/6

8:15 am-3:10 pm

1 stop5h 55m

$313

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 3/2

6:45 am-11:13 am

1 stop5h 28m

$98

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 20 results

Compare providers for flights from Buffalo to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Cheapfaremart	Price Accuracy-	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Buffalo-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

How far ahead should I book a flight from Buffalo to St. Louis?

The best time to book flights from Buffalo to St. Louis is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $112). Flying from Buffalo to St. Louis in November is currently the most expensive (average of $291). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STL?

One of the essential ways to save on airfare from Buffalo to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 21% on airfare.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,250 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,011 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,066 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,047 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Buffalo to St. Louis?
There are many flights that can get you from Buffalo to St. Louis in 4h 36m. Fly via Southwest, American Airlines, or Delta to get the fastest option. There are 672 mi between Buffalo and St. Louis. This flight may include one or multiple stops.
What are the cheapest airlines flying from Buffalo to St. Louis round-trip?
Our cheapest airline available from Buffalo to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $164 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $243 and $296 round-trip. Delta is currently priced 53% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Buffalo to St. Louis one-way?
To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $95. Southwest flights start at $119 while deals on Delta start at $125 one-way.
Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?
Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.
Can I find deals for business class flights from Buffalo to St. Louis?
Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $112). Flying from Buffalo to St. Louis in November is currently the most expensive (average of $291). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

St. Louis car rentals

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Other flights to St. Louis

Top 4 airlines flying from Buffalo to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$164	Average$346	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$243	Average$338	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$296	Average$517	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$338	Average$467	FlexibilityNo cancel fee	On-time63%

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$98+ Cheap flights from Buffalo to St. Louis (BUF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Buffalo to St. Louis with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheapflights Tip: The best prices from Buffalo to Lambert-St Louis are usually found in September or July, booked 29 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Find flight deals from Buffalo to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Compare providers for flights from Buffalo to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in December.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

How far ahead should I book a flight from Buffalo to St. Louis?

What is the cheapest month to book a flight from Buffalo to St. Louis?

What is the cheapest time of day to fly from BUF to STL?

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Buffalo to St. Louis?

What are the cheapest airlines flying from Buffalo to St. Louis round-trip?

What are the cheapest airlines to fly from Buffalo to St. Louis one-way?

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

How can I find direct flights from Buffalo to St. Louis?

Can I find deals for business class flights from Buffalo to St. Louis?

What is the cheapest month to book a flight from Buffalo to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Buffalo to St. Louis

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Top 4 airlines flying from Buffalo to St. Louis

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Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.