$115+ Cheap flights from Buffalo to St. Louis (BUF - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Oct 3 — Oct 101
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to St. Louis
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Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
This CheapOair deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:49 pm -
1 stop28h 45m
Mon 9/285:19 pm -
1 stop23h 30m
Deal found 8/29![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:53 pm -
1 stop11h 20m
Wed 10/286:44 pm -
2 stops22h 08m
Deal found 8/31![Frontier logo]()
$286
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:41 pm -
1 stop14h 06m
Sun 12/66:05 pm -
1 stop15h 38m
Deal found 8/30![Frontier logo]()
$289
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:20 am -
1 stop3h 45m
Thu 11/125:45 am -
1 stop3h 40m
Deal found 9/1![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:35 pm -
1 stop5h 35m
Thu 10/295:25 am -
1 stop4h 00m
Deal found 9/2![Southwest logo]()
$309
This Trip.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:40 pm -
2 stops22h 52m
Wed 10/72:29 pm -
2 stops20h 29m
Deal found 9/2![Frontier logo]()
$316
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:20 am -
1 stop4h 09m
Wed 10/76:47 am -
1 stop3h 48m
Deal found 9/2![Delta logo]()
$322
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:20 pm -
1 stop5h 40m
Wed 10/78:30 am -
2 stops5h 50m
Deal found 9/2![Southwest logo]()
$327
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:36 am -
1 stop6h 46m
Sat 9/55:02 pm -
1 stop15h 21m
Deal found 8/30![Frontier logo]()
$330
Best flights from Buffalo to St. LouisDiscover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop7h 45m
Mon 11/26:40 am -
1 stop4h 20m
Deal found 9/1![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:58 pm -
1 stop4h 40m
Sat 9/269:04 am -
1 stop6h 39m
Deal found 9/2![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
1 stop6h 00m
Sun 11/13:51 pm -
1 stop7h 08m
Deal found 8/30![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:20 pm -
1 stop5h 40m
Wed 10/78:30 am -
2 stops5h 50m
Deal found 9/2![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:45 pm -
1 stop6h 35m
Wed 10/285:50 am -
1 stop3h 35m
Deal found 8/31![Southwest logo]()
$356
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:10 am -
1 stop5h 19m
Sat 9/268:54 am -
1 stop7h 49m
Deal found 8/29![American Airlines logo]()
$392
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
2 stops7h 15m
Thu 10/295:25 am -
2 stops5h 35m
Deal found 8/31![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:00 pm -
2 stops6h 55m
Sat 9/268:30 am -
2 stops8h 10m
Deal found 9/2![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
1 stop6h 00m
Sun 11/15:45 am -
1 stop3h 40m
Deal found 9/1![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:35 pm -
2 stops7h 30m
Sun 10/115:50 pm -
1 stop5h 25m
Deal found 8/29![Southwest logo]()
$407
Last-minute flights from Buffalo to St. LouisDiscover last-minute flight deals from Buffalo to St. Louis. Data last updated September 3, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated September 3, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:29 pm -
1 stop18h 59m
Mon 9/74:23 pm -
1 stop16h 00m
Deal found 8/31![Frontier logo]()
$340
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:36 am -
1 stop6h 46m
Sat 9/55:02 pm -
1 stop15h 21m
Deal found 8/30![Frontier logo]()
$330
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:20 am -
1 stop4h 09m
Wed 9/94:10 pm -
1 stop5h 25m
Deal found 8/31![Delta logo]()
$345
This CheapOair deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:49 pm -
1 stop28h 45m
Mon 9/285:19 pm -
1 stop23h 30m
Deal found 8/29![Frontier logo]()
$251
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:58 pm -
1 stop4h 40m
Sat 9/269:04 am -
1 stop6h 39m
Deal found 9/2![United Airlines logo]()
$337
This Trip.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:40 pm -
2 stops22h 52m
Wed 10/72:29 pm -
2 stops20h 29m
Deal found 9/2![Frontier logo]()
$316
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:20 am -
1 stop4h 09m
Wed 10/76:47 am -
1 stop3h 48m
Deal found 9/2![Delta logo]()
$322
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:20 pm -
1 stop5h 40m
Wed 10/78:30 am -
2 stops5h 50m
Deal found 9/2![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:53 pm -
1 stop11h 20m
Wed 10/286:44 pm -
2 stops22h 08m
Deal found 8/31![Frontier logo]()
$286
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:35 pm -
1 stop5h 35m
Thu 10/295:25 am -
1 stop4h 00m
Deal found 9/2![Southwest logo]()
$309
One-way flights from Buffalo to St. LouisSearch for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 3, 2026.
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:51 pm -
2 stops19h 19m
Deal found 9/1![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:51 pm -
2 stops23h 49m
Deal found 8/30![Frontier logo]()
$116
This CheapOair deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2712:49 pm -
1 stop28h 45m
Deal found 8/29![Frontier logo]()
$122
This Frontier deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:53 pm -
1 stop11h 20m
Deal found 8/31![Frontier logo]()
$135
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:00 pm -
1 stop4h 40m
Deal found 9/1![Southwest logo]()
$155
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:00 pm -
1 stop7h 15m
Deal found 9/2![Southwest logo]()
$173
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:53 pm -
2 stops7h 38m
Deal found 9/2![United Airlines logo]()
$178
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:05 am -
1 stop3h 55m
Deal found 8/30![Southwest logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:40 pm -
2 stops22h 37m
Deal found 9/2![Frontier logo]()
$201
Find flight deals from Buffalo to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $251 (CheapOair) |
One-way from | $115 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $321 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 3, 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Mon 10/26
4:30 pm-11:15 pm
1 stop7h 45m
Lambert-St Louis
Mon 11/2
6:40 am-12:00 pm
1 stop4h 20m
$309
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Fri 10/2
2:20 pm-7:00 pm
1 stop5h 40m
Lambert-St Louis
Wed 10/7
8:30 am-3:20 pm
2 stops5h 50m
$327
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Wed 9/23
5:58 pm-9:38 pm
1 stop4h 40m
Lambert-St Louis
Sat 9/26
9:04 am-4:43 pm
1 stop6h 39m
$337
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Thu 10/22
5:45 pm-11:20 pm
1 stop6h 35m
Lambert-St Louis
Wed 10/28
5:50 am-10:25 am
1 stop3h 35m
$356
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Thu 10/22
6:00 am-12:15 pm
2 stops7h 15m
Lambert-St Louis
Thu 10/29
5:25 am-12:00 pm
2 stops5h 35m
$377
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Thu 10/29
8:00 am-1:00 pm
1 stop6h 00m
Lambert-St Louis
Sun 11/1
3:51 pm-11:59 pm
1 stop7h 08m
$381
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Wed 9/23
12:00 pm-5:55 pm
2 stops6h 55m
Lambert-St Louis
Sat 9/26
8:30 am-5:40 pm
2 stops8h 10m
$383
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Wed 9/23
6:10 am-10:29 am
1 stop5h 19m
Lambert-St Louis
Sat 9/26
8:54 am-5:43 pm
1 stop7h 49m
$392
Quickest round-trip
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Sun 10/25
8:00 am-1:00 pm
1 stop6h 00m
Lambert-St Louis
Sun 11/1
5:45 am-10:25 am
1 stop3h 40m
$397
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Fri 10/9
12:35 pm-7:05 pm
2 stops7h 30m
Lambert-St Louis
Sun 10/11
5:50 pm-12:15 am
1 stop5h 25m
$407
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Buffalo to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Buffalo-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
BUF-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to St. Louis
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $321). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $676). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to St. Louis?
Airfare is below average for this route at the moment.
Buffalo to St. Louis flights typically cost between $308 and $386 in September.The cheapest round-trip price found within the last 5 days was $251 on Frontier (Sep 17-Sep 28).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 3, 2026.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
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Buffalo and St. Louis flights
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 3, 2026.
Top 3 airlines flying from Buffalo to St. Louis
Discover the top 3 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$256 | Average$387 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$317 | Average$413 | FlexibilityNo cancel fee | On-time63% |