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$129+ Cheap flights from Buffalo to St. Louis (BUF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Buffalo to Lambert-St Louis are usually found in September or July, booked 82 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$154
(Mytrip)

One-way from

$129
(Flightnetwork)

Popular in

October

Cheapest in

September

Average price

$341
Provider with most accurate pricing for Buffalo-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Lambert-St Louis flights.
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From Buffalo to Lambert-St Louis
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One-way flight from Buffalo to Lambert-St Louis
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:40 amBUF - STL
1 stop13h 17mFrontier
Mon 11/244:13 pmSTL - BUF
1 stop24h 39mFrontier
Deal found 11/5$154
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2211:47 amBUF - STL
1 stop22h 42mFrontier
Mon 11/244:13 pmSTL - BUF
1 stop24h 39mFrontier
Deal found 11/5$222
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:40 amBUF - STL
1 stop13h 17mMultiple Airlines
Mon 11/247:04 pmSTL - BUF
2 stops37h 25mMultiple Airlines
Deal found 11/5$265
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amBUF - STL
1 stop5h 24mDelta
Mon 12/86:05 pmSTL - BUF
1 stop3h 53mDelta
Deal found 11/4$279
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:27 amBUF - STL
1 stop9h 52mAmerican Airlines
Tue 12/166:52 amSTL - BUF
1 stop4h 13mAmerican Airlines
Deal found 11/5$285
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:05 pmBUF - STL
1 stop4h 59mAmerican Airlines
Wed 12/310:13 amSTL - BUF
1 stop6h 37mAmerican Airlines
Deal found 11/3$288
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:52 amBUF - STL
1 stop13h 05mFrontier
Sun 11/233:14 pmSTL - BUF
1 stop17h 12mFrontier
Deal found 11/5$292
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amBUF - STL
1 stop7h 40mDelta
Mon 12/85:15 pmSTL - BUF
1 stop4h 47mDelta
Deal found 11/5$301
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:24 amBUF - STL
2 stops23h 33mMultiple Airlines
Sun 11/233:14 pmSTL - BUF
1 stop17h 12mMultiple Airlines
Deal found 11/5$303
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:50 pmBUF - STL
1 stop10h 09mAmerican Airlines
Mon 12/84:49 pmSTL - BUF
1 stop5h 50mAmerican Airlines
Deal found 11/4$307
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:40 pmBUF - STL
1 stop6h 10mSouthwest
Tue 12/165:10 amSTL - BUF
2 stops8h 10mSouthwest
Deal found 11/5$317

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Buffalo

Fly to

St. Louis

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 11/20

11:40 am-11:57 pm

1 stop13h 17m

Lambert-St Louis

Mon 11/24

4:13 pm-5:52 pm

1 stop24h 39m

$154

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 1/17

6:00 am-12:36 pm

1 stop7h 36m

Lambert-St Louis

Tue 1/20

5:56 pm-10:59 pm

1 stop4h 03m

$257

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 11/20

11:40 am-11:57 pm

1 stop13h 17m

Lambert-St Louis

Mon 11/24

7:04 pm-9:29 am

2 stops37h 25m

$265

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 1/12

6:38 pm-11:39 pm

1 stop6h 01m

Lambert-St Louis

Tue 1/13

9:45 am-4:55 pm

1 stop6h 10m

$279

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 12/6

6:00 am-10:24 am

1 stop5h 24m

Lambert-St Louis

Mon 12/8

6:05 pm-10:58 pm

1 stop3h 53m

$279

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 12/12

7:27 am-4:19 pm

1 stop9h 52m

Lambert-St Louis

Tue 12/16

6:52 am-12:05 pm

1 stop4h 13m

$285

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 1/12

3:45 pm-9:55 pm

2 stops7h 10m

Lambert-St Louis

Tue 1/13

11:35 am-8:30 pm

2 stops7h 55m

$289

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 11/21

11:52 am-11:57 pm

1 stop13h 05m

Lambert-St Louis

Sun 11/23

3:14 pm-9:26 am

1 stop17h 12m

$292

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 12/4

6:00 am-12:40 pm

1 stop7h 40m

Lambert-St Louis

Mon 12/8

5:15 pm-11:02 pm

1 stop4h 47m

$301

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 2/26

9:57 am-10:33 pm

1 stop13h 36m

Lambert-St Louis

Sun 3/1

8:45 am-8:13 pm

1 stop10h 28m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 21 results
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Compare providers for flights from Buffalo to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

How far ahead should I book a flight from Buffalo to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to St. Louis. Price data was last updated on October 31, 2025.

The best time to book flights from Buffalo to St. Louis is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $112). Flying from Buffalo to St. Louis in November is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STL?

Find hourly flight availability from Buffalo to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

One of the essential ways to save on airfare from Buffalo to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 21% on airfare.

How much does it cost to fly round-trip from Buffalo to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,007 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    There are many flights that can get you from Buffalo to St. Louis in 7h 36m. Fly via Frontier or Delta to get the fastest option. There are 672 mi between Buffalo and St. Louis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Buffalo to St. Louis round-trip?

    Our cheapest airline available from Buffalo to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $166 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $243 and $296 round-trip. Delta is currently priced 53% below the average price you’ll pay for this route.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $112). Flying from Buffalo to St. Louis in November is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Buffalo to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Buffalo to St. Louis

Discover the top 4 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$166Average$346FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$356FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$296Average$517FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$326Average$436FlexibilityNo cancel feeOn-time63%

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