$155+ Cheap flights from Buffalo to St. Louis (BUF - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to St. Louis
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Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This CheapOair deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:54 pm -
1 stop11h 22m
Sat 10/314:26 pm -
1 stop25h 26m
Deal found 9/29![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:39 pm -
1 stop10h 33m
Thu 12/106:13 pm -
1 stop18h 31m
Deal found 9/28![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:20 pm -
1 stop27h 39m
Fri 11/271:20 pm -
1 stop6h 04m
Deal found 9/28![Frontier logo]()
$274
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:00 pm -
1 stop6h 25m
Tue 11/36:20 am -
1 stop3h 20m
Deal found 9/29![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:09 pm -
1 stop5h 28m
Mon 12/71:43 pm -
1 stop7h 12m
Deal found 9/27![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:25 am -
2 stops7h 20m
Mon 12/711:20 am -
1 stop8h 25m
Deal found 9/27![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:05 pm -
2 stops6h 55m
Mon 12/213:55 pm -
1 stop5h 35m
Deal found 9/25![Southwest logo]()
$346
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop5h 18m
Fri 10/3011:31 am -
1 stop4h 37m
Deal found 9/25![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:09 pm -
1 stop5h 28m
Sun 12/135:02 am -
1 stop4h 54m
Deal found 9/28![American Airlines logo]()
$353
Best flights from Buffalo to St. LouisDiscover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:00 pm -
1 stop4h 05m
Tue 11/310:55 am -
2 stops6h 15m
Deal found 9/29![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/35:30 am -
1 stop7h 57m
Sun 3/77:05 am -
1 stop7h 20m
Deal found 9/29![American Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:46 am -
1 stop5h 57m
Mon 10/261:08 pm -
1 stop6h 28m
Deal found 9/29![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:35 pm -
1 stop6h 30m
Sat 11/75:45 am -
2 stops8h 10m
Deal found 9/25![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:20 am -
1 stop3h 45m
Fri 11/65:45 am -
1 stop3h 40m
Deal found 9/29![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
2 stops7h 15m
Sat 10/317:00 am -
2 stops8h 05m
Deal found 9/27![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:35 pm -
2 stops7h 30m
Fri 10/305:25 am -
1 stop4h 00m
Deal found 9/25![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:45 pm -
2 stops7h 40m
Mon 12/72:20 pm -
2 stops6h 35m
Deal found 9/27![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/312:45 pm -
2 stops10h 00m
Sun 3/78:20 am -
1 stop6h 20m
Deal found 9/25![Southwest logo]()
$388
Last-minute flights from Buffalo to St. LouisDiscover last-minute flight deals from Buffalo to St. Louis. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated September 30, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:49 pm -
1 stop28h 45m
Sat 10/104:30 pm -
1 stop24h 22m
Deal found 9/28![Frontier logo]()
$412
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:53 am -
1 stop5h 04m
Mon 10/195:00 am -
1 stop4h 53m
Deal found 9/27![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:46 am -
1 stop5h 57m
Mon 10/261:08 pm -
1 stop6h 28m
Deal found 9/27![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop5h 18m
Fri 10/3011:31 am -
1 stop4h 37m
Deal found 9/25![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:35 pm -
2 stops7h 30m
Fri 10/305:25 am -
1 stop4h 00m
Deal found 9/25![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:00 pm -
1 stop6h 25m
Tue 11/36:20 am -
1 stop3h 20m
Deal found 9/29![Southwest logo]()
$309
This CheapOair deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:54 pm -
1 stop11h 22m
Sat 10/314:26 pm -
1 stop25h 26m
Deal found 9/29![Frontier logo]()
$258
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
2 stops7h 15m
Sat 10/317:00 am -
2 stops8h 05m
Deal found 9/27![Southwest logo]()
$373
One-way flights from Buffalo to St. LouisSearch for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:49 pm -
1 stop4h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![United Airlines logo]()
$155
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:10 pm -
2 stops7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$160
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:05 pm -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$175
This Frontier deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:53 pm -
1 stop11h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Frontier logo]()
$185
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/173:45 pm -
1 stop4h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:51 pm -
2 stops23h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Frontier logo]()
$240
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am -
1 stop8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:48 pm -
1 stop6h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$267
Find flight deals from Buffalo to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $258 (CheapOair) |
One-way from | $155 (United Airlines) |
Popular in | March |
Cheapest in | January |
Average price | $361 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Fri 11/6
9:15 am-7:00 pm
1 stop10h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$175
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Mon 10/12
3:53 pm-8:51 pm
1 stop5h 58m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$249
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Tue 10/13
1:48 pm-7:41 pm
1 stop6h 53m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$249
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Mon 10/12
5:30 am-1:20 pm
1 stop8h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$249
Quickest round-trip
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Sun 1/17
1:50 pm-6:08 pm
1 stop5h 18m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$249
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Sun 10/11
12:02 pm-5:19 pm
1 stop6h 17m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$249
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Tue 10/6
12:35 pm-7:00 pm
2 stops7h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$272
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Sun 10/11
6:30 am-3:21 pm
2 stops9h 51m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$304
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Tue 10/27
7:00 pm-10:05 pm
1 stop4h 05m
Lambert-St Louis
Tue 11/3
10:55 am-6:10 pm
2 stops6h 15m
$314
BuffaloSt. Louis
BUF Buffalo - STL Lambert-St Louis
BUFSTL
Buffalo
Mon 11/2
6:35 pm-12:05 am
1 stop6h 30m
Lambert-St Louis
Sat 11/7
5:45 am-2:55 pm
2 stops8h 10m
$314
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Buffalo to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Buffalo-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
BUF-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to St. Louis
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $321). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $676). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to St. Louis?
Airfare is below average for this route at the moment.
Buffalo to St. Louis flights typically cost between $291 and $546 in October.The cheapest round-trip price found within the last 5 days was $258 on Frontier (Oct 29-Oct 31).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 30, 2026.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Chesterfield
Maryland Heights
Collinsville
Edwardsville
Glencoe
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Buffalo and St. Louis flights
Browse other Buffalo and St. Louis flight options. Last updated on September 30, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on September 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 30, 2026.
Top 3 airlines flying from Buffalo to St. Louis
Discover the top 3 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$423 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$317 | Average$412 | FlexibilityNo cancel fee | On-time63% |