HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$341+ Cheap flights from Biloxi, MS to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/21. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — STL
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Biloxi to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Biloxi to St. Louis

Cheapest flights from Biloxi to St. Louis
Explore the most affordable flight options available from Biloxi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Delta deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amGPT - STL
1 stop6h 03mDelta
Wed 12/315:13 pmSTL - GPT
1 stop4h 27mDelta
Deal found 12/12$349
This Delta deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amGPT - STL
1 stop6h 57mDelta
Tue 12/233:41 pmSTL - GPT
1 stop5h 59mDelta
Deal found 12/12$394
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:15 pmGPT - STL
1 stop4h 40mUnited Airlines
Mon 1/58:15 amSTL - GPT
2 stops13h 22mUnited Airlines
Deal found 12/12$414
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:17 amGPT - STL
1 stop5h 19mAmerican Airlines
Tue 12/233:30 pmSTL - GPT
1 stop7h 27mAmerican Airlines
Deal found 12/12$503
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:19 amGPT - STL
1 stop5h 31mAmerican Airlines
Wed 12/316:00 amSTL - GPT
2 stops12h 27mAmerican Airlines
Deal found 12/12$514
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:58 pmGPT - STL
1 stop4h 58mAmerican Airlines
Mon 12/297:00 amSTL - GPT
1 stop7h 02mAmerican Airlines
Deal found 12/13$544
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:05 amGPT - STL
2 stops48h 51mMultiple Airlines
Sat 12/274:27 pmSTL - GPT
1 stop26h 43mMultiple Airlines
Deal found 12/14$637

Find flight deals from Biloxi to St. Louis

Keep the following information in mind while searching for Biloxi to St. Louis flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$344
(United Airlines)

One-way from

$341
(Delta)

Popular in

August

Cheapest in

January

Average price

$480
Provider with most accurate pricing for Gulfport Biloxi Regional-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Lambert-St Louis flights.
Search Deals
From Biloxi to Lambert-St Louis
Search Deals
One-way flight from Biloxi to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Biloxi to St. Louis that are best for you.

Fly from

Biloxi

Fly to

St. Louis

Route

Depart

Return

Price

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Fri 1/30

5:13 pm-10:00 pm

1 stop4h 47m

Lambert-St Louis

Tue 2/3

7:00 am-7:48 pm

2 stops12h 48m

$344

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 12/27

6:00 am-12:03 pm

1 stop6h 03m

Lambert-St Louis

Wed 12/31

5:13 pm-9:40 pm

1 stop4h 27m

$349

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Mon 12/29

5:15 pm-9:55 pm

1 stop4h 40m

Lambert-St Louis

Mon 1/5

8:15 am-9:37 pm

2 stops13h 22m

$414

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 12/27

5:19 am-10:50 am

1 stop5h 31m

Lambert-St Louis

Wed 12/31

6:00 am-6:27 pm

2 stops12h 27m

$514

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sun 12/21

5:21 pm-11:42 pm

1 stop6h 21m

$341

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sun 12/21

1:57 pm-10:43 pm

2 stops8h 46m

$555

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Best time to book a flight from Biloxi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to St. Louis

What is the cheapest month to book a flight from Biloxi to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Biloxi to St. Louis (average of $75). Flying from Biloxi to St. Louis in March is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to STL?

Find hourly flight availability from Biloxi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

One of the essential ways to save on airfare from Biloxi to St. Louis is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 13% on airfare.

What is the cheapest day to fly from Biloxi to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Biloxi to St. Louis flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 15, 2025.
Read through reviews of airlines operating flights from Biloxi to St. Louis, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Biloxi?

    If you book a flight to St. Louis from Biloxi, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis. There are 0 flights from Biloxi to Lambert-St Louis per day from 5 different airlines.

  • How popular is this Biloxi to St. Louis flight route?

    This flight path from Biloxi to Lambert-St Louis was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Biloxi to St. Louis?

    United Airlines can get you from Biloxi to St. Louis in just under 4h 47m. Your travel time can differ by up to . The distance between Biloxi and St. Louis is about 581 mi.

  • What are the cheapest flights from Biloxi to St. Louis?

    While on average a flight from Biloxi to St. Louis is generally $350, our data shows the cheapest flight currently is $108. When looking at the most popular route, (Gulfport Biloxi Regional - Lambert-St Louis), you can expect to pay $344 for that flight.

  • Can I find deals for flights from Biloxi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Biloxi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to St. Louis.

  • Can I find deals for business class flights from Biloxi to St. Louis?

    Yes. Cheapflights offers flight deals from Biloxi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Biloxi to St. Louis (average of $75). Flying from Biloxi to St. Louis in March is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Biloxi to St. Louis

Discover the top 5 airlines that operate flights from Biloxi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$72Average$184FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$218Average$314FlexibilityNo cancel feeOn-time69%
DeltaCheapest$239Average$320FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$364FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$278Average$391FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.