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St. Louis

$229+ Cheap flights from Biloxi, MS to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — STL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Biloxi to St. Louis

Cheapest flights from Biloxi to St. Louis
Explore the most affordable flight options available from Biloxi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:11 pmGPT - STL
1 stop4h 47mUnited Airlines
Sat 12/64:45 pmSTL - GPT
1 stop4h 37mUnited Airlines
Deal found 10/27$249
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:54 pmGPT - STL
1 stop6h 36mAmerican Airlines
Sat 12/61:59 pmSTL - GPT
2 stops9h 54mAmerican Airlines
Deal found 10/27$254
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:52 amGPT - STL
1 stop6h 55mUnited Airlines
Sat 11/158:20 amSTL - GPT
1 stop7h 42mUnited Airlines
Deal found 10/26$259
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:15 pmGPT - STL
1 stop5h 07mUnited Airlines
Mon 11/248:20 amSTL - GPT
1 stop7h 42mUnited Airlines
Deal found 10/27$263
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:21 pmGPT - STL
1 stop6h 17mDelta
Fri 1/23:41 pmSTL - GPT
1 stop5h 59mDelta
Deal found 10/28$274
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:20 amGPT - STL
1 stop5h 19mAmerican Airlines
Tue 11/117:00 amSTL - GPT
1 stop5h 37mAmerican Airlines
Deal found 10/26$289
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/71:45 pmGPT - STL
2 stops10h 11mAmerican Airlines
Mon 11/102:17 pmSTL - GPT
2 stops8h 27mAmerican Airlines
Deal found 10/26$314
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:45 pmGPT - STL
1 stop6h 19mDelta
Sat 11/83:59 pmSTL - GPT
1 stop5h 51mDelta
Deal found 10/27$319
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:43 amGPT - STL
1 stop6h 31mAmerican Airlines
Sat 11/81:39 pmSTL - GPT
2 stops10h 18mAmerican Airlines
Deal found 10/27$324

Cheap flight deals from Biloxi to St. Louis

Keep the following information in mind while searching for Biloxi to St. Louis flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$229
(Delta)

Popular in

August

Cheapest in

January

Average price

$529
Provider with most accurate pricing for Gulfport Biloxi Regional-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Lambert-St Louis flights.
Search Deals
From Biloxi to Lambert-St Louis
Search Deals
One-way flight from Biloxi to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Biloxi to St. Louis that are best for you.

Fly from

Biloxi

Fly to

St. Louis

Route

Depart

Return

Price

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Thu 12/4

5:11 pm-9:58 pm

1 stop4h 47m

Lambert-St Louis

Sat 12/6

4:45 pm-9:22 pm

1 stop4h 37m

$249

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Thu 12/11

2:53 pm-9:02 pm

1 stop6h 09m

Lambert-St Louis

Thu 12/18

6:00 am-9:50 am

1 stop3h 50m

$249

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 2/21

3:00 pm-7:14 pm

1 stop4h 14m

Lambert-St Louis

Tue 2/24

7:30 am-1:37 pm

1 stop6h 07m

$249

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Thu 12/4

12:54 pm-7:30 pm

1 stop6h 36m

Lambert-St Louis

Sat 12/6

1:59 pm-11:53 pm

2 stops9h 54m

$254

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Mon 11/17

5:15 pm-10:22 pm

1 stop5h 07m

Lambert-St Louis

Mon 11/24

8:20 am-4:02 pm

1 stop7h 42m

$263

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 11/11

11:52 am-6:47 pm

1 stop6h 55m

Lambert-St Louis

Sat 11/15

10:00 am-9:36 pm

2 stops11h 36m

$264

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Wed 12/24

5:21 pm-11:38 pm

1 stop6h 17m

Lambert-St Louis

Fri 1/2

3:41 pm-9:40 pm

1 stop5h 59m

$274

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 2/21

5:00 am-11:00 am

1 stop6h 00m

Lambert-St Louis

Tue 2/24

4:01 pm-11:49 pm

2 stops7h 48m

$324

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 2/21

4:55 pm-10:14 pm

1 stop5h 19m

Lambert-St Louis

Tue 2/24

7:00 am-7:34 pm

2 stops12h 34m

$324

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 11/22

3:30 pm-9:58 pm

1 stop6h 28m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 11 results
1
2

Best time to book a flight from Biloxi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to St. Louis

What is the cheapest month to book a flight from Biloxi to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Biloxi to St. Louis (average of $106). Flying from Biloxi to St. Louis in March is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to STL?

Find hourly flight availability from Biloxi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

One of the essential ways to save on airfare from Biloxi to St. Louis is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 16% on airfare.

What is the cheapest day to fly from Biloxi to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to St. Louis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Biloxi to St. Louis flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Biloxi to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Biloxi to St. Louis, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Biloxi?

    If you book a flight to St. Louis from Biloxi, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis. There are 0 flights from Biloxi to Lambert-St Louis per day from 5 different airlines.

  • How popular is this Biloxi to St. Louis flight route?

    This flight path from Biloxi to Lambert-St Louis was viewed by 10 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Biloxi to St. Louis?

    United Airlines and Delta can get you from Biloxi to St. Louis in just under 4h 47m. Your travel time can differ by up to 1h 22m. The distance between Biloxi and St. Louis is about 581 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest flights from Biloxi to St. Louis?

    While on average a flight from Biloxi to St. Louis is generally $280, our data shows the cheapest flight currently is $124. When looking at the most popular route, (Gulfport Biloxi Regional - Lambert-St Louis), you can expect to pay $249 for that flight.

  • Can I find deals for flights from Biloxi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Biloxi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to St. Louis.

  • Can I find deals for business class flights from Biloxi to St. Louis?

    Yes. Cheapflights offers flight deals from Biloxi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to St. Louis?

    Currently, January is the cheapest month in which you can book a flight from Biloxi to St. Louis (average of $106). Flying from Biloxi to St. Louis in March is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Top 5 airlines flying from Biloxi to St. Louis

Discover the top 5 airlines that operate flights from Biloxi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$72Average$184FlexibilityNo cancel feeOn-time62%
DeltaCheapest$198Average$301FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$218Average$378FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$331FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$278Average$394FlexibilityNo cancel feeOn-time63%

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