HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spartanburg

$64+ Cheap flights from St. Louis (STL) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Spartanburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to Spartanburg are usually found in August or October, booked 67 days in advance, depart on a Wednesday or Thursday and return on a Saturday

Cheap flight deals from St. Louis to Spartanburg

Cheapest flights from St. Louis to Spartanburg
Explore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This Mytrip deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:30 pmSTL - CLT
1 stop17h 07mFrontier
Sun 12/219:33 pmCLT - STL
1 stop13h 12mFrontier
Deal found 12/7$197
This Booking.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:07 amSTL - CLT
1 stop6h 54mFrontier
Mon 12/299:43 pmCLT - STL
1 stop25h 50mFrontier
Deal found 12/6$225
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:05 amSTL - CLT
Nonstop2h 02mAmerican Airlines
Tue 12/3012:15 pmCLT - STL
Nonstop1h 59mAmerican Airlines
Deal found 12/6$252
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:27 pmSTL - CLT
1 stop20h 29mFrontier
Mon 1/198:19 pmCLT - STL
1 stop28h 14mFrontier
Deal found 12/8$255
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:27 pmSTL - CLT
1 stop20h 29mFrontier
Sun 1/1811:21 amCLT - STL
2 stops20h 30mFrontier
Deal found 12/8$259
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:30 pmSTL - CLT
1 stop5h 08mFrontier
Mon 12/222:51 pmCLT - STL
1 stop8h 42mFrontier
Deal found 12/7$264
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:30 pmSTL - CLT
1 stop27h 55mMultiple Airlines
Sun 12/217:42 pmCLT - STL
2 stops38h 58mMultiple Airlines
Deal found 12/7$267
This Gotogate deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:51 amSTL - CLT
1 stop10h 38mMultiple Airlines
Tue 12/309:24 pmCLT - STL
1 stop26h 09mMultiple Airlines
Deal found 12/6$269
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:27 pmSTL - CLT
1 stop26h 42mMultiple Airlines
Mon 1/199:07 pmCLT - STL
2 stops34h 44mMultiple Airlines
Deal found 12/7$270
This Mytrip deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:37 pmSTL - CLT
1 stop17h 24mFrontier
Sun 12/219:33 pmCLT - STL
1 stop13h 12mFrontier
Deal found 12/7$273
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:04 pmSTL - CLT
Nonstop1h 56mAmerican Airlines
Mon 12/296:26 pmCLT - STL
Nonstop2h 04mAmerican Airlines
Deal found 12/8$276

Find flight deals from St. Louis to Spartanburg

Keep the following information in mind while searching for St. Louis to Spartanburg flight deals. Data was last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$138
(Gotogate)

One-way from

$64
(Frontier)

Popular in

April

Cheapest in

August

Average price

$314
Provider with most accurate pricing for Lambert-St Louis-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Charlotte Douglas flights.
Search Deals
From Lambert-St Louis to Spartanburg
Search Deals
One-way flight from Lambert-St Louis to Spartanburg
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from St. Louis to Spartanburg that are best for you.

Fly from

St. Louis

Fly to

Spartanburg

Route

Depart

Return

Price

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 1/1

5:00 am-7:59 am

Nonstop1h 59m

Charlotte Douglas

Tue 1/6

10:09 pm-11:12 pm

Nonstop2h 03m

$228

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Fri 1/16

2:55 pm-5:40 pm

Nonstop1h 45m

Charlotte Douglas

Sun 1/18

8:25 am-9:35 am

Nonstop2h 10m

$240

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 2/26

5:00 pm-7:45 pm

Nonstop1h 45m

Charlotte Douglas

Mon 3/2

6:30 pm-10:40 pm

1 stop5h 10m

$249

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 1/8

2:30 pm-5:15 pm

Nonstop1h 45m

Charlotte Douglas

Sat 1/10

7:00 am-9:45 am

1 stop3h 45m

$249

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 2/12

5:00 pm-7:45 pm

Nonstop1h 45m

Charlotte Douglas

Tue 2/17

7:30 pm-10:35 pm

1 stop4h 05m

$250

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 1/22

10:01 pm-4:18 pm

2 stops17h 17m

Charlotte Douglas

Thu 1/29

9:58 pm-10:23 am

1 stop13h 25m

$251

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 12/18

4:27 pm-1:56 pm

1 stop20h 29m

Charlotte Douglas

Sun 1/18

11:21 am-6:51 am

2 stops20h 30m

$259

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Thu 2/12

6:35 am-12:08 pm

1 stop4h 33m

Charlotte Douglas

Tue 2/17

5:25 am-9:06 am

1 stop4h 41m

$260

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 1/21

6:30 am-2:13 pm

2 stops6h 43m

Charlotte Douglas

Wed 1/21

6:30 pm-11:59 pm

1 stop6h 29m

$260

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Fri 1/16

2:55 pm-5:40 pm

Nonstop1h 45m

Charlotte Douglas

Mon 1/19

5:05 pm-6:15 pm

Nonstop2h 10m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from St. Louis to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Spartanburg

How far ahead should I book a flight from St. Louis to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Spartanburg. Price data was last updated on December 5, 2025.

The price you pay for your flight from St. Louis to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 67 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Spartanburg?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Spartanburg (average of $126). Flying from St. Louis to Spartanburg in March is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SB1?

Find hourly flight availability from St. Louis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

One of the essential ways to save on airfare from St. Louis to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 25% on airfare.

What is the cheapest day to fly from St. Louis to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their St. Louis to Spartanburg flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from St. Louis to Spartanburg

Explore weekly flight availability from St. Louis to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 8, 2025.

The most flights from STL to SB1 are scheduled on a Friday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated December 8, 2025.
Read reviews from past customers who have flown Southwest, American Airlines, and Frontier from St. Louis to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,252 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,252 reviews
Southwest
8.0
Very good
4,252 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,044 reviews
Southwest
8.0
Very good
4,252 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.8
Fair
3,087 reviews
Southwest
8.0
Very good
4,252 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Spartanburg?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Spartanburg. On average, Lambert-St Louis has 6 outbound flights to Spartanburg per day from 4 airlines. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How popular is this St. Louis to Spartanburg flight route?

    This flight path from Lambert-St Louis to Spartanburg was viewed by 10 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from St. Louis to Spartanburg?

    For as low as $240, American Airlines can have you in Spartanburg from St. Louis in 1h 45m. The distance between St. Louis and Spartanburg is about 574 mi. All flights are typically nonstop.

  • What are the cheapest airlines to fly from St. Louis to Spartanburg one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $112. Delta flights start at $118 while deals on American Airlines start at $143 one-way.

  • What are the most reliable airlines from St. Louis to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from St. Louis to Spartanburg consider choosing American Airlines (84%), British Airways (79%) or Southwest (70%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from St. Louis to Spartanburg?

    While on average a flight from St. Louis to Spartanburg is generally $356, our data shows the cheapest flight currently is $125. When looking at the most popular route, (Lambert-St Louis - Charlotte Douglas), you can expect to pay $143 for that flight.

  • Can I find deals for flights from St. Louis to Spartanburg that include hotel bookings?

    Yes. In addition to deals on St. Louis to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Spartanburg.

  • Can I find deals for business class flights from St. Louis to Spartanburg?

    Yes. Cheapflights offers flight deals from St. Louis to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Spartanburg?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Spartanburg (average of $126). Flying from St. Louis to Spartanburg in March is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Spartanburg

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Charlotte flights
St. Louis to Savannah flights
Kansas City to Charlotte flights
Kansas City to Savannah flights
Kansas City to Charleston flights
St. Louis to Myrtle Beach flights
St. Louis to Charleston flights
Kansas City to Myrtle Beach flights
St. Louis to Columbia flights
Kansas City to Augusta flights
Springfield to Charleston flights
Springfield to Savannah flights
Kansas City to Columbia flights
Kansas City to Greenville flights
Springfield to Charlotte flights
Springfield to Greenville flights
St. Louis to Augusta flights
Columbia to Charleston flights
St. Louis to Greenville flights
Columbia to Charlotte flights
St. Louis to Hilton Head Island flights
Springfield to Columbia flights
Springfield to Myrtle Beach flights
Joplin to Charlotte flights
Kansas City to Hilton Head Island flights
Joplin to Columbia flights
Columbia to Hilton Head Island flights
Joplin to Savannah flights
Joplin to Charleston flights
Columbia to Myrtle Beach flights
Springfield to Hilton Head Island flights
Joplin to Augusta flights
St. Louis to Florence flights
Springfield to Augusta flights
Joplin to Hilton Head Island flights
Cape Girardeau to Charlotte flights
Kansas City to Florence flights

Top 4 airlines flying from St. Louis to Spartanburg

Discover the top 4 airlines that operate flights from St. Louis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$140Average$190FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$197Average$323FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$213Average$337FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$311FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.