$95+ Cheap flights from St. Louis (STL) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
Aug 9 — Aug 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Spartanburg are usually found in January or August, booked 79 days in advance, depart on a Wednesday or Friday and return on a Saturday
Cheap flight deals from St. Louis to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to SpartanburgExplore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:54 am
STL
- CLT
Nonstop1h 55m
American Airlines
Tue 8/1810:00 pm
CLT
- STL
Nonstop1h 55m
American Airlines
Deal found 7/8![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/2411:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/8![Southwest logo]()
$194
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am
STL
- CLT
1 stop5h 00m
Southwest
Tue 11/106:20 pm
CLT
- STL
Nonstop2h 10m
Southwest
Deal found 7/8![Southwest logo]()
$199
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Wed 8/268:30 am
CLT
- STL
1 stop7h 20m
Southwest
Deal found 7/8![Southwest logo]()
$202
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:45 pm
STL
- CLT
1 stop5h 05m
Southwest
Mon 8/1711:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/9![Southwest logo]()
$204
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
STL
- CLT
1 stop6h 10m
Delta
Wed 8/125:30 am
CLT
- STL
1 stop5h 24m
Delta
Deal found 7/7![Delta logo]()
$209
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:23 pm
STL
- CLT
1 stop5h 34m
Delta
Mon 8/1011:50 am
CLT
- STL
1 stop5h 27m
Delta
Deal found 7/7![Delta logo]()
$211
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:45 pm
STL
- CLT
Nonstop1h 45m
Southwest
Mon 10/199:00 pm
CLT
- STL
1 stop3h 35m
Southwest
Deal found 7/8![Southwest logo]()
$212
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:52 pm
STL
- CLT
1 stop6h 33m
Delta
Mon 8/248:10 am
CLT
- STL
1 stop4h 36m
Delta
Deal found 7/8![Delta logo]()
$213
Best flights from St. Louis to SpartanburgDiscover carefully curated flight deals from St. Louis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from St. Louis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:23 pm
STL
- CLT
1 stop5h 34m
Delta
Mon 8/1011:50 am
CLT
- STL
1 stop5h 27m
Delta
Deal found 7/7![Delta logo]()
$211
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:20 pm
STL
- CLT
1 stop6h 30m
Southwest
Mon 8/247:40 am
CLT
- STL
2 stops8h 40m
Southwest
Deal found 7/8![Southwest logo]()
$219
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:25 am
STL
- CLT
2 stops10h 31m
United Airlines
Wed 9/27:00 am
CLT
- STL
2 stops8h 57m
United Airlines
Deal found 7/9![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:25 pm
STL
- CLT
Nonstop1h 45m
Southwest
Wed 10/711:15 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/7![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
STL
- CLT
1 stop4h 11m
Delta
Sun 10/47:39 pm
CLT
- STL
1 stop5h 03m
Delta
Deal found 7/9![Delta logo]()
$268
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:05 am
STL
- CLT
2 stops9h 20m
Southwest
Sat 9/56:30 am
CLT
- STL
2 stops10h 00m
Southwest
Deal found 7/9![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:25 am
STL
- CLT
2 stops8h 30m
United Airlines
Fri 8/287:00 am
CLT
- STL
2 stops9h 38m
United Airlines
Deal found 7/9![United Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:10 am
STL
- CLT
2 stops9h 30m
Southwest
Sun 9/277:35 am
CLT
- STL
1 stop5h 45m
Southwest
Deal found 7/9![Southwest logo]()
$287
Last-minute flights from St. Louis to SpartanburgDiscover last-minute flight deals from St. Louis to Spartanburg. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Spartanburg. Data last updated July 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- CLT
1 stop4h 03m
Delta
Tue 8/1111:50 am
CLT
- STL
1 stop5h 27m
Delta
Deal found 7/7![Delta logo]()
$211
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:10 am
STL
- CLT
2 stops9h 30m
Southwest
Mon 8/1011:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/8![Southwest logo]()
$217
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
STL
- CLT
1 stop6h 10m
Delta
Wed 8/125:30 am
CLT
- STL
1 stop5h 24m
Delta
Deal found 7/7![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:45 pm
STL
- CLT
1 stop5h 05m
Southwest
Mon 8/1711:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/9![Southwest logo]()
$204
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:54 am
STL
- CLT
Nonstop1h 55m
American Airlines
Tue 8/1810:00 pm
CLT
- STL
Nonstop1h 55m
American Airlines
Deal found 7/8![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:45 am
STL
- CLT
1 stop5h 35m
Southwest
Tue 8/188:30 am
CLT
- STL
2 stops9h 15m
Southwest
Deal found 7/8![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/2411:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/8![Southwest logo]()
$194
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Wed 8/268:30 am
CLT
- STL
1 stop7h 20m
Southwest
Deal found 7/8![Southwest logo]()
$202
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:52 pm
STL
- CLT
1 stop6h 33m
Delta
Mon 8/248:10 am
CLT
- STL
1 stop4h 36m
Delta
Deal found 7/8![Delta logo]()
$213
One-way flights from St. Louis to SpartanburgSearch for one-way flight options from St. Louis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
Search for one-way flight options from St. Louis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:45 pm
STL
- CLT
Nonstop1h 45m
Southwest
Deal found 7/8![Southwest logo]()
$95
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:35 pm
STL
- CLT
Nonstop1h 45m
Southwest
Deal found 7/9![Southwest logo]()
$97
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:04 pm
STL
- CLT
1 stop4h 17m
Delta
Deal found 7/8![Delta logo]()
$105
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:59 pm
STL
- CLT
1 stop3h 46m
Delta
Deal found 7/8![Delta logo]()
$107
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:45 am
STL
- CLT
2 stops7h 40m
Southwest
Deal found 7/7![Southwest logo]()
$110
This Trip.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:09 pm
STL
- CLT
1 stop23h 49m
Frontier
Deal found 7/6![Frontier logo]()
$114
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- CLT
1 stop4h 03m
Delta
Deal found 7/8![Delta logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:34 pm
STL
- CLT
2 stops17h 19m
Frontier
Deal found 7/9![Frontier logo]()
$125
This Travelocity deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:34 pm
STL
- CLT
1 stop23h 31m
Frontier
Deal found 7/5![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:35 am
STL
- CLT
2 stops26h 12m
Frontier
Deal found 7/8![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:57 pm
STL
- CLT
2 stops24h 06m
Frontier
Deal found 7/8![Frontier logo]()
$129
Find flight deals from St. Louis to Spartanburg
Keep the following information in mind while searching for St. Louis to Spartanburg flight deals. Data was last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $189 (American Airlines) |
One-way from | $95 (Southwest) |
Popular in | May |
Cheapest in | January |
Average price | $350 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from St. Louis to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Tue 8/4
5:23 pm-11:57 pm
1 stop5h 34m
Charlotte Douglas
Mon 8/10
11:50 am-4:17 pm
1 stop5h 27m
$211
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 8/20
2:20 pm-9:50 pm
1 stop6h 30m
Charlotte Douglas
Mon 8/24
7:40 am-3:20 pm
2 stops8h 40m
$219
Quickest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sun 10/4
4:25 pm-7:10 pm
Nonstop1h 45m
Charlotte Douglas
Wed 10/7
11:15 am-12:10 pm
Nonstop1h 55m
$266
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 10/1
6:00 am-11:11 am
1 stop4h 11m
Charlotte Douglas
Sun 10/4
7:39 pm-11:42 pm
1 stop5h 03m
$268
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 9/3
6:05 am-4:25 pm
2 stops9h 20m
Charlotte Douglas
Sat 9/5
6:30 am-3:30 pm
2 stops10h 00m
$276
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 9/24
10:10 am-8:40 pm
2 stops9h 30m
Charlotte Douglas
Sun 9/27
7:35 am-12:20 pm
1 stop5h 45m
$287
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Tue 9/1
7:25 am-6:56 pm
2 stops10h 31m
Charlotte Douglas
Wed 9/2
7:00 am-2:57 pm
2 stops8h 57m
$300
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 8/26
7:25 am-4:55 pm
2 stops8h 30m
Charlotte Douglas
Fri 8/28
7:00 am-3:38 pm
2 stops9h 38m
$328
Cheapest one-way
Quickest one-way
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Tue 10/6
3:45 pm-6:30 pm
Nonstop1h 45m
$95
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 10/8
5:35 pm-8:20 pm
Nonstop1h 45m
$97
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from St. Louis with our price prediction graph.
STL-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Spartanburg
STL-SB1
STL-CLT
What is the cheapest time of day to fly from STL to SB1?
Find hourly flight availability from St. Louis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 10, 2026.
One of the essential ways to save on airfare from St. Louis to Spartanburg is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 31% on airfare.
Weekly flight availability from St. Louis to Spartanburg
Explore weekly flight availability from St. Louis to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 10, 2026.
The most flights from STL to SB1 are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from St. Louis to Spartanburg?
What is the cheapest day to fly from St. Louis to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spartanburg. Price data was last updated on July 4, 2026.
Travelers seeking maximum savings on their St. Louis to Spartanburg flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated July 10, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from St. Louis to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Top destinations
Alternative routes for St. Louis to Spartanburg
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Spartanburg by cabin class
Find flights from St. Louis to Spartanburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Spartanburg flights
Browse other St. Louis and Spartanburg flight options. Last updated on July 10, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
St. Louis to Spartanburg flights
Consider these flights traveling from St. Louis to Spartanburg.
Top 4 airlines flying from St. Louis to Spartanburg
Discover the top 4 airlines that operate flights from St. Louis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$132 | Average$326 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$152 | Average$291 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$197 | Average$413 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$217 | Average$358 | FlexibilityNo cancel fee | On-time71% |