$82+ Cheap flights from St. Louis (STL) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
May 12 — May 191
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Spartanburg are usually found in January or August, booked 73 days in advance, depart on a Wednesday or Friday and return on a Saturday
Cheap flight deals from St. Louis to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to SpartanburgExplore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
Explore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
This Frontier deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:06 pm
STL
- CLT
1 stop8h 53m
Frontier
Tue 5/268:55 am
CLT
- STL
1 stop10h 11m
Frontier
Deal found 4/10![Frontier logo]()
$185
This CheapOair deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- CLT
1 stop22h 36m
Frontier
Sun 4/267:50 am
CLT
- STL
1 stop16h 29m
Frontier
Deal found 4/10![Frontier logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:12 pm
STL
- CLT
Nonstop2h 03m
American Airlines
Wed 6/247:35 am
CLT
- STL
Nonstop1h 58m
American Airlines
Deal found 4/11![American Airlines logo]()
$197
This CheapOair deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:19 pm
STL
- CLT
1 stop18h 15m
Frontier
Sat 6/1312:29 pm
CLT
- STL
1 stop12h 40m
Frontier
Deal found 4/10![Frontier logo]()
$216
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
STL
- CLT
1 stop4h 32m
Delta
Wed 6/245:30 am
CLT
- STL
1 stop3h 46m
Delta
Deal found 4/11![Delta logo]()
$217
This CheapOair deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:19 pm
STL
- CLT
1 stop23h 24m
Frontier
Sat 5/301:00 pm
CLT
- STL
1 stop11h 57m
Frontier
Deal found 4/11![Frontier logo]()
$236
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:45 pm
STL
- CLT
2 stops7h 55m
Southwest
Tue 6/910:40 am
CLT
- STL
2 stops7h 50m
Southwest
Deal found 4/9![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:51 am
STL
- CLT
1 stop7h 35m
American Airlines
Wed 5/137:26 am
CLT
- STL
Nonstop2h 04m
American Airlines
Deal found 4/10![American Airlines logo]()
$249
This Travelocity deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:06 pm
STL
- CLT
1 stop8h 53m
Frontier
Sun 5/247:14 pm
CLT
- STL
1 stop25h 09m
Frontier
Deal found 4/8![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:59 pm
STL
- CLT
1 stop22h 36m
Frontier
Wed 4/228:09 pm
CLT
- STL
2 stops15h 21m
Frontier
Deal found 4/10![Frontier logo]()
$253
Best flights from St. Louis to SpartanburgDiscover carefully curated flight deals from St. Louis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
Discover carefully curated flight deals from St. Louis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:45 pm
STL
- CLT
2 stops7h 55m
Southwest
Tue 6/910:40 am
CLT
- STL
2 stops7h 50m
Southwest
Deal found 4/9![Southwest logo]()
$248
This Frontier deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:21 pm
STL
- CLT
1 stop9h 54m
Frontier
Sun 8/91:12 pm
CLT
- STL
1 stop12h 02m
Frontier
Deal found 4/11![Frontier logo]()
$315
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
STL
- CLT
1 stop6h 31m
Delta
Tue 7/2812:19 pm
CLT
- STL
1 stop4h 55m
Delta
Deal found 4/6![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:41 pm
STL
- CLT
1 stop6h 04m
United Airlines
Tue 6/910:27 am
CLT
- STL
2 stops11h 49m
United Airlines
Deal found 4/8![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 am
STL
- CLT
2 stops7h 55m
Southwest
Sat 8/291:00 pm
CLT
- STL
1 stop6h 15m
Southwest
Deal found 4/7![Southwest logo]()
$288
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:00 am
STL
- CLT
1 stop4h 31m
Delta
Mon 8/1011:45 am
CLT
- STL
1 stop5h 12m
Delta
Deal found 4/11![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:40 am
STL
- CLT
1 stop4h 30m
Southwest
Mon 7/274:40 pm
CLT
- STL
Nonstop2h 10m
Southwest
Deal found 4/6![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:23 am
STL
- CLT
2 stops8h 39m
United Airlines
Sun 5/316:00 am
CLT
- STL
2 stops7h 11m
United Airlines
Deal found 4/9![United Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/23:35 pm
STL
- CLT
2 stops6h 40m
Southwest
Sun 7/59:20 pm
CLT
- STL
1 stop3h 35m
Southwest
Deal found 4/10![Southwest logo]()
$341
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:30 am
STL
- CLT
2 stops9h 50m
Southwest
Sat 9/266:30 am
CLT
- STL
2 stops7h 15m
Southwest
Deal found 4/11![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:30 pm
STL
- CLT
Nonstop1h 50m
Southwest
Tue 8/48:05 am
CLT
- STL
1 stop4h 15m
Southwest
Deal found 4/10![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:10 am
STL
- CLT
2 stops9h 30m
Southwest
Sun 8/94:50 pm
CLT
- STL
2 stops7h 10m
Southwest
Deal found 4/11![Southwest logo]()
$373
Last-minute flights from St. Louis to SpartanburgDiscover last-minute flight deals from St. Louis to Spartanburg. Data last updated April 12, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Spartanburg. Data last updated April 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/194:59 pm
STL
- CLT
2 stops15h 11m
Multiple Airlines
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:59 pm
STL
- CLT
1 stop22h 36m
Frontier
Wed 4/228:09 pm
CLT
- STL
2 stops15h 21m
Frontier
Deal found 4/10![Frontier logo]()
$253
This CheapOair deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- CLT
1 stop22h 36m
Frontier
Sun 4/267:50 am
CLT
- STL
1 stop16h 29m
Frontier
Deal found 4/10![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:59 pm
STL
- CLT
1 stop22h 31m
Frontier
Sun 5/312:16 pm
CLT
- STL
1 stop12h 03m
Frontier
Deal found 4/7![Frontier logo]()
$257
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:51 am
STL
- CLT
1 stop7h 35m
American Airlines
Wed 5/137:26 am
CLT
- STL
Nonstop2h 04m
American Airlines
Deal found 4/10![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:45 pm
STL
- CLT
1 stop6h 10m
Southwest
Wed 5/136:25 pm
CLT
- STL
1 stop4h 45m
Southwest
Deal found 4/10![Southwest logo]()
$259
This CheapOair deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:19 pm
STL
- CLT
1 stop23h 24m
Frontier
Sat 5/301:00 pm
CLT
- STL
1 stop11h 57m
Frontier
Deal found 4/11![Frontier logo]()
$236
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:20 pm
STL
- CLT
1 stop5h 33m
Delta
Sat 5/305:30 pm
CLT
- STL
1 stop5h 08m
Delta
Deal found 4/8![Delta logo]()
$258
This Frontier deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:06 pm
STL
- CLT
1 stop8h 53m
Frontier
Tue 5/268:55 am
CLT
- STL
1 stop10h 11m
Frontier
Deal found 4/10![Frontier logo]()
$185
This Travelocity deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:06 pm
STL
- CLT
1 stop8h 53m
Frontier
Sun 5/247:14 pm
CLT
- STL
1 stop25h 09m
Frontier
Deal found 4/8![Frontier logo]()
$250
One-way flights from St. Louis to SpartanburgSearch for one-way flight options from St. Louis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
Search for one-way flight options from St. Louis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
This CheapOair deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:19 pm
STL
- CLT
1 stop18h 46m
Frontier
Deal found 4/10![Frontier logo]()
$82
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:30 pm
STL
- CLT
1 stop11h 29m
Frontier
Deal found 4/8![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:19 pm
STL
- CLT
1 stop18h 46m
Frontier
Deal found 4/10![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:19 pm
STL
- CLT
1 stop23h 24m
Frontier
Deal found 4/11![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:19 pm
STL
- CLT
1 stop18h 15m
Frontier
Deal found 4/10![Frontier logo]()
$94
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:58 pm
STL
- CLT
1 stop11h 17m
Frontier
Deal found 4/8![Frontier logo]()
$95
This Expedia deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 4/7![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:27 pm
STL
- CLT
2 stops17h 07m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:31 pm
STL
- CLT
2 stops22h 17m
Frontier
Deal found 4/10![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
STL
- CLT
2 stops16h 48m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:27 pm
STL
- CLT
2 stops17h 07m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$106
Find flight deals from St. Louis to Spartanburg
Keep the following information in mind while searching for St. Louis to Spartanburg flight deals. Data was last updated April 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $185 (Frontier) |
One-way from | $82 (CheapOair) |
Popular in | May |
Cheapest in | January |
Average price | $328 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from St. Louis to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 6/1
1:45 pm-10:40 pm
2 stops7h 55m
Charlotte Douglas
Tue 6/9
10:40 am-5:30 pm
2 stops7h 50m
$248
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 6/17
5:40 am-2:35 pm
2 stops7h 55m
Charlotte Douglas
Sat 8/29
1:00 pm-6:15 pm
1 stop6h 15m
$288
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 7/22
5:40 am-11:10 am
1 stop4h 30m
Charlotte Douglas
Mon 7/27
4:40 pm-5:50 pm
Nonstop2h 10m
$309
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 8/6
8:21 pm-7:15 am
1 stop9h 54m
Charlotte Douglas
Sun 8/9
1:12 pm-12:14 am
1 stop12h 02m
$315
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 7/23
6:00 am-1:31 pm
1 stop6h 31m
Charlotte Douglas
Tue 7/28
12:19 pm-4:14 pm
1 stop4h 55m
$325
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sat 8/8
8:00 am-1:31 pm
1 stop4h 31m
Charlotte Douglas
Mon 8/10
11:45 am-3:57 pm
1 stop5h 12m
$325
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 7/2
3:35 pm-11:15 pm
2 stops6h 40m
Charlotte Douglas
Sun 7/5
9:20 pm-11:55 pm
1 stop3h 35m
$341
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sat 9/19
8:30 am-7:20 pm
2 stops9h 50m
Charlotte Douglas
Sat 9/26
6:30 am-12:45 pm
2 stops7h 15m
$348
Quickest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sun 8/2
4:30 pm-7:20 pm
Nonstop1h 50m
Charlotte Douglas
Tue 8/4
8:05 am-11:20 am
1 stop4h 15m
$352
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sun 5/31
5:41 pm-12:45 am
1 stop6h 04m
Charlotte Douglas
Tue 6/9
10:27 am-9:16 pm
2 stops11h 49m
$365
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from St. Louis with our price prediction graph.
STL-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Spartanburg
STL-SB1
STL-CLT
How far ahead should I book a flight from St. Louis to Spartanburg?
Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Spartanburg. Price data was last updated on April 9, 2026.
The price you pay for your flight from St. Louis to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 73 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from St. Louis to Spartanburg?
Currently, January is the cheapest month in which you can book a flight from St. Louis to Spartanburg (average of $137). Flying from St. Louis to Spartanburg in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SB1?
Find hourly flight availability from St. Louis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 12, 2026.
One of the essential ways to save on airfare from St. Louis to Spartanburg is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 32% on airfare.
What is the cheapest day to fly from St. Louis to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spartanburg. Price data was last updated on April 11, 2026.
Travelers seeking maximum savings on their St. Louis to Spartanburg flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from St. Louis to Spartanburg
Explore weekly flight availability from St. Louis to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 12, 2026.
The most flights from STL to SB1 are scheduled on a Sunday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from St. Louis to Spartanburg?
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated April 12, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from St. Louis to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Spartanburg
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Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Spartanburg by cabin class
Find flights from St. Louis to Spartanburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Spartanburg flights
Browse other St. Louis and Spartanburg flight options. Last updated on April 12, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on April 12, 2026.
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St. Louis to Spartanburg flights
Consider these flights traveling from St. Louis to Spartanburg.
Top 4 airlines flying from St. Louis to Spartanburg
Discover the top 4 airlines that operate flights from St. Louis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$132 | Average$336 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$152 | Average$198 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$196 | Average$353 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$213 | Average$341 | FlexibilityNo cancel fee | On-time71% |