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Spartanburg

$82+ Cheap flights from St. Louis (STL) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Spartanburg are usually found in January or August, booked 67 days in advance, depart on a Wednesday or Thursday and return on a Saturday

Cheap flight deals from St. Louis to Spartanburg

Cheapest flights from St. Louis to Spartanburg
Explore the most affordable flight options available from St. Louis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:39 am
STL
-
CLT
1 stop6h 34m
Frontier
Fri 5/16:30 pm
CLT
-
STL
1 stop26h 02m
Frontier
Deal found 3/30$151
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:59 pm
STL
-
CLT
1 stop22h 36m
Frontier
Tue 4/215:30 pm
CLT
-
STL
1 stop6h 49m
Frontier
Deal found 3/31$171
This Expedia deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:41 am
STL
-
CLT
1 stop14h 55m
Frontier
Sun 4/128:10 am
CLT
-
STL
1 stop24h 41m
Frontier
Deal found 3/27$180
This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:59 pm
STL
-
CLT
1 stop22h 36m
Frontier
Fri 4/176:30 pm
CLT
-
STL
1 stop26h 02m
Frontier
Deal found 3/30$191
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:19 pm
STL
-
CLT
1 stop18h 46m
Frontier
Sun 5/107:58 pm
CLT
-
STL
1 stop5h 23m
Frontier
Deal found 3/31$192
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:30 am
STL
-
CLT
Nonstop2h 00m
American Airlines
Tue 6/97:35 am
CLT
-
STL
Nonstop1h 58m
American Airlines
Deal found 3/31$197
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:59 pm
STL
-
CLT
1 stop15h 38m
Frontier
Tue 4/145:30 pm
CLT
-
STL
1 stop6h 49m
Frontier
Deal found 3/30$201
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:30 pm
STL
-
CLT
1 stop6h 10m
Southwest
Tue 6/91:25 pm
CLT
-
STL
Nonstop2h 00m
Southwest
Deal found 3/31$207
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:58 pm
STL
-
CLT
1 stop11h 17m
Frontier
Sun 6/147:14 pm
CLT
-
STL
1 stop25h 09m
Frontier
Deal found 3/31$210
This Expedia deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
STL
-
CLT
1 stop21h 06m
Frontier
Mon 5/251:00 pm
CLT
-
STL
1 stop12h 21m
Frontier
Deal found 3/27$211
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:59 pm
STL
-
CLT
1 stop22h 36m
Frontier
Mon 5/411:33 am
CLT
-
STL
1 stop12h 46m
Frontier
Deal found 3/27$212

Find flight deals from St. Louis to Spartanburg

Keep the following information in mind while searching for St. Louis to Spartanburg flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$151
(CheapOair)

One-way from

$82
(CheapOair)

Popular in

March

Cheapest in

January

Average price

$317
Provider with most accurate pricing for Lambert-St Louis-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Charlotte Douglas flights.
Search Deals
From Lambert-St Louis to Spartanburg
Search Deals
One-way flight from Lambert-St Louis to Spartanburg
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from St. Louis to Spartanburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 6/2

2:30 pm-9:40 pm

1 stop6h 10m

Charlotte Douglas

Tue 6/9

7:50 am-2:50 pm

2 stops8h 00m

$222
Quickest round-trip

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 6/10

4:50 pm-7:40 pm

Nonstop1h 50m

Charlotte Douglas

Sun 6/14

9:20 pm-11:55 pm

1 stop3h 35m

$260

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Mon 5/4

5:28 pm-12:45 am

1 stop6h 17m

Charlotte Douglas

Wed 5/6

6:25 pm-11:57 pm

1 stop6h 32m

$318

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 4/14

1:45 pm-8:55 pm

1 stop6h 10m

Charlotte Douglas

Tue 5/12

6:20 pm-10:10 pm

1 stop4h 50m

$322

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 4/15

5:35 am-12:55 pm

2 stops6h 20m

Charlotte Douglas

Wed 5/6

6:40 am-3:15 pm

2 stops9h 35m

$332

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Mon 6/1

1:13 pm-9:29 pm

1 stop7h 16m

Charlotte Douglas

Tue 6/9

10:27 am-9:16 pm

2 stops11h 49m

$344
Cheapest one-way

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Sat 5/30

10:19 am-3:50 pm

1 stop4h 31m

$109

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 4/28

6:00 am-1:43 pm

1 stop6h 43m

$109

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Fri 5/15

4:19 pm-12:05 pm

1 stop18h 46m

$123

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Mon 4/27

4:41 pm-9:27 pm

1 stop3h 46m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Best time to book a flight from St. Louis to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Spartanburg

How far ahead should I book a flight from St. Louis to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Spartanburg. Price data was last updated on March 13, 2026.

The price you pay for your flight from St. Louis to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 67 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Spartanburg?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Spartanburg (average of $137). Flying from St. Louis to Spartanburg in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SB1?

Find hourly flight availability from St. Louis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2026.

One of the essential ways to save on airfare from St. Louis to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 44% on airfare.

What is the cheapest day to fly from St. Louis to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spartanburg. Price data was last updated on March 28, 2026.

Travelers seeking maximum savings on their St. Louis to Spartanburg flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from St. Louis to Spartanburg?

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated April 1, 2026.
Read reviews from past customers who have flown Southwest,American Airlines, andFrontier from St. Louis to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,336 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,336 reviews
Southwest
8.0
Very good
4,336 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,545 reviews
Southwest
8.0
Very good
4,336 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Frontier
5.7
Fair
3,006 reviews
Southwest
8.0
Very good
4,336 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Spartanburg?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Spartanburg. On average, Lambert-St Louis has 2 outbound flights to Spartanburg per day from 4 airlines. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How popular is this St. Louis to Spartanburg flight route?

    This flight path from Lambert-St Louis to Spartanburg was viewed by 22 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from St. Louis to Spartanburg?

    For as low as $222, Southwest can have you in Spartanburg from St. Louis in 6h 10m. The distance between St. Louis and Spartanburg is about 574 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Spartanburg one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $112. Delta flights start at $118 while deals on American Airlines start at $157 one-way.

  • What are the most reliable airlines from St. Louis to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from St. Louis to Spartanburg consider choosing American Airlines (85%), Southwest (80%) or British Airways (76%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from St. Louis to Spartanburg?

    While on average a flight from St. Louis to Spartanburg is generally $424, our data shows the cheapest flight currently is $142. When looking at the most popular route, (Lambert-St Louis - Charlotte Douglas), you can expect to pay $197 for that flight.

  • Can I find deals for flights from St. Louis to Spartanburg that include hotel bookings?

    Yes. In addition to deals on St. Louis to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Spartanburg.

  • Can I find deals for business class flights from St. Louis to Spartanburg?

    Yes. Cheapflights offers flight deals from St. Louis to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Spartanburg?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Spartanburg (average of $137). Flying from St. Louis to Spartanburg in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from St. Louis to Spartanburg

Discover the top 4 airlines that operate flights from St. Louis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$152Average$220FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$196Average$353FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$213Average$344FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$325FlexibilityNo cancel feeOn-timeN/A

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