HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spartanburg

$95+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Spartanburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Myrtle Beach to Spartanburg

Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated September 16, 2025.

Round-trip from

$191
(Kiwi.com)

One-way from

$95
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$426
From Myrtle Beach Intl to Spartanburg
Search Deals
One-way flight from Myrtle Beach Intl to Spartanburg
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Myrtle Beach to Spartanburg

Cheapest flights from Myrtle Beach to Spartanburg
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:14 amMYR - CLT
1 stop14h 47mSpirit Airlines
Tue 11/46:00 amCLT - MYR
1 stop14h 55mSpirit Airlines
Deal found 9/15$191
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:59 amMYR - CLT
1 stop13h 23mSpirit Airlines
Sat 12/135:45 amCLT - MYR
1 stop9h 13mSpirit Airlines
Deal found 9/14$204
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:54 pmMYR - CLT
1 stop5h 53mSpirit Airlines
Tue 11/115:06 pmCLT - MYR
2 stops17h 35mSpirit Airlines
Deal found 9/14$206
This KAYAK deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:46 amMYR - CLT
2 stops20h 51mSpirit Airlines
Wed 11/129:46 pmCLT - MYR
2 stops14h 10mSpirit Airlines
Deal found 9/14$210
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:54 pmMYR - CLT
1 stop5h 53mMultiple Airlines
Sat 11/152:16 pmCLT - MYR
1 stop18h 33mMultiple Airlines
Deal found 9/14$213
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:59 amMYR - CLT
1 stop8h 37mMultiple Airlines
Sat 11/152:16 pmCLT - MYR
1 stop18h 33mMultiple Airlines
Deal found 9/14$216
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:54 pmMYR - CLT
1 stop5h 53mSpirit Airlines
Fri 11/149:46 pmCLT - MYR
2 stops12h 55mSpirit Airlines
Deal found 9/14$217
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:59 amMYR - CLT
1 stop8h 37mSpirit Airlines
Fri 11/149:46 pmCLT - MYR
2 stops12h 55mSpirit Airlines
Deal found 9/14$219
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:54 pmMYR - CLT
1 stop5h 53mSpirit Airlines
Mon 11/101:39 pmCLT - MYR
1 stop7h 15mSpirit Airlines
Deal found 9/14$221
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:12 amMYR - CLT
1 stop11h 35mSpirit Airlines
Fri 11/149:46 pmCLT - MYR
2 stops12h 55mSpirit Airlines
Deal found 9/14$228
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:43 pmMYR - CLT
1 stop13h 04mMultiple Airlines
Tue 10/212:35 pmCLT - MYR
1 stop22h 13mMultiple Airlines
Deal found 9/15$232

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.

Fly from

Myrtle Beach

Fly to

Spartanburg

Route

Depart

Return

Price

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 10/29

8:14 am-11:01 pm

1 stop14h 47m

Charlotte Douglas

Tue 11/4

6:00 am-8:55 pm

1 stop14h 55m

$191

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Tue 12/9

9:59 am-11:22 pm

1 stop13h 23m

Charlotte Douglas

Sat 12/13

5:45 am-2:58 pm

1 stop9h 13m

$204

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 11/8

12:54 pm-6:47 pm

1 stop5h 53m

Charlotte Douglas

Wed 11/12

1:39 pm-8:54 pm

1 stop7h 15m

$210

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 11/8

12:54 pm-6:47 pm

1 stop5h 53m

Charlotte Douglas

Tue 11/11

7:31 pm-2:58 pm

1 stop19h 27m

$212

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 11/8

12:54 pm-6:47 pm

1 stop5h 53m

Charlotte Douglas

Sat 11/15

2:16 pm-8:49 am

1 stop18h 33m

$213

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 11/8

12:54 pm-6:47 pm

1 stop5h 53m

Charlotte Douglas

Fri 11/14

9:46 pm-10:41 am

2 stops12h 55m

$217

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 10/13

6:43 pm-7:47 am

1 stop13h 04m

Charlotte Douglas

Tue 10/21

6:00 am-12:48 pm

1 stop6h 48m

$232

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 10/17

8:14 am-11:29 pm

1 stop15h 15m

Charlotte Douglas

Wed 10/22

6:00 am-12:48 pm

1 stop6h 48m

$234

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 11/8

12:54 pm-6:47 pm

1 stop5h 53m

Charlotte Douglas

Sun 11/9

5:06 pm-10:41 am

2 stops17h 35m

$234

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 11/8

12:54 pm-6:47 pm

1 stop5h 53m

Charlotte Douglas

Sat 11/15

9:46 pm-10:41 am

2 stops12h 55m

$236

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 17 results
1
2

Best time to book a flight from Myrtle Beach to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spartanburg

What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $248). Flying from Myrtle Beach to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SB1?

Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Spartanburg as you normally would.

What is the cheapest day to fly from Myrtle Beach to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Myrtle Beach to Spartanburg

Explore weekly flight availability from Myrtle Beach to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from MYR to SB1 are scheduled on a Thursday (11 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (7 on average).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spartanburg?

    For a flight from Myrtle Beach to Spartanburg, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city. Myrtle Beach Intl is the only Myrtle Beach airport and it handles 9 outbound flights to Spartanburg per day. 1 airline has flights to Spartanburg from Myrtle Beach Intl on a regular basis.

  • How long is the flight from Myrtle Beach to Spartanburg?

    There are many flights that can get you from Myrtle Beach to Spartanburg in 14h 47m. Fly via Spirit Airlines to get the fastest option. Airlines will cover a distance of 157 mi.

  • What are the most reliable airlines from Myrtle Beach to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from Myrtle Beach to Spartanburg consider choosing Piedmont Airlines (96%), American Airlines (83%) or Envoy Air (80%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Myrtle Beach to Spartanburg?

    On average you can expect to pay $664 for a flight from Myrtle Beach to Spartanburg. The cheapest flight overall is $110 while the most popular route, (Myrtle Beach Intl - Charlotte Douglas) is currently priced at $191.

  • Can I find deals for flights from Myrtle Beach to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spartanburg.

  • Can I find deals for business class flights from Myrtle Beach to Spartanburg?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $248). Flying from Myrtle Beach to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Spartanburg

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Myrtle Beach flights
Greenville to Charleston flights
Greenville to Savannah flights
Charlotte to Charleston flights
Savannah to Charlotte flights
Myrtle Beach to Charlotte flights
Charlotte to Greenville flights
Charlotte to Savannah flights
Charleston to Charlotte flights
Columbia to Charlotte flights
Greenville to Charlotte flights
Charleston to Myrtle Beach flights
Myrtle Beach to Greenville flights
Charlotte to Hilton Head Island flights
Charlotte to Columbia flights
Greenville to Myrtle Beach flights
Myrtle Beach to Charleston flights
Charleston to Savannah flights
Charlotte to Augusta flights
Augusta to Myrtle Beach flights
Columbia to Charleston flights
Hilton Head Island to Savannah flights

Top airline flying from Myrtle Beach to Spartanburg

Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$246Average$347FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.