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$60+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
feb. 28 — mar. 71
sáb. 2/28
sáb. 3/7
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Spartanburg

Cheapest flights from Myrtle Beach to Spartanburg
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/2410:09 am
MYR
-
CLT
1 stop9h 08m
Multiple Airlines
mar. 3/35:54 pm
CLT
-
MYR
1 stop21h 01m
Multiple Airlines
Deal found 1/27$145
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/259:54 pm
MYR
-
CLT
1 stop21h 23m
Multiple Airlines
mié. 3/43:12 pm
CLT
-
MYR
1 stop5h 27m
Multiple Airlines
Deal found 1/27$152
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2811:57 am
MYR
-
CLT
1 stop7h 52m
Multiple Airlines
dom. 3/19:21 am
CLT
-
MYR
1 stop11h 18m
Multiple Airlines
Deal found 1/27$157
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/2410:09 am
MYR
-
CLT
1 stop27h 34m
Spirit Airlines
mar. 3/39:21 am
CLT
-
MYR
1 stop5h 34m
Spirit Airlines
Deal found 1/27$160
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/139:54 pm
MYR
-
CLT
1 stop21h 55m
Multiple Airlines
mar. 2/175:54 pm
CLT
-
MYR
1 stop15h 04m
Multiple Airlines
Deal found 1/27$177
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/118:15 pm
MYR
-
CLT
1 stop15h 51m
Multiple Airlines
sáb. 2/145:54 pm
CLT
-
MYR
1 stop26h 45m
Multiple Airlines
Deal found 1/28$181
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/186:15 am
MYR
-
CLT
1 stop7h 28m
Spirit Airlines
mié. 2/187:13 pm
CLT
-
MYR
1 stop13h 00m
Spirit Airlines
Deal found 1/27$186
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/29:58 am
MYR
-
CLT
1 stop11h 19m
Multiple Airlines
mar. 3/35:54 pm
CLT
-
MYR
1 stop21h 01m
Multiple Airlines
Deal found 1/27$187
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/2510:09 am
MYR
-
CLT
1 stop10h 03m
Spirit Airlines
mié. 3/49:21 am
CLT
-
MYR
3 stops22h 52m
Spirit Airlines
Deal found 1/27$190

Find flight deals from Myrtle Beach to Spartanburg

Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated enero 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$145
(Kiwi.com)

One-way from

$60
(Expedia)

Popular in

October

Cheapest in

August

Average price

$473
Provider with most accurate pricing for Myrtle Beach Intl-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Charlotte Douglas flights.
Search Deals
From Myrtle Beach Intl to Spartanburg
Search Deals
One-way flight from Myrtle Beach Intl to Spartanburg
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($120 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.

Fly from

Myrtle Beach

Fly to

Spartanburg

Route

Depart

Return

Price

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mar. 2/24

10:09 am-7:17 pm

1 stop9h 08m

Charlotte Douglas

mar. 3/3

5:54 pm-2:55 pm

1 stop21h 01m

$145

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mié. 2/25

9:54 pm-7:17 pm

1 stop21h 23m

Charlotte Douglas

mié. 3/4

3:12 pm-8:39 pm

1 stop5h 27m

$152

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

sáb. 2/28

11:57 am-7:49 pm

1 stop7h 52m

Charlotte Douglas

dom. 3/1

9:21 am-8:39 pm

1 stop11h 18m

$157

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

vie. 2/13

9:54 pm-7:49 pm

1 stop21h 55m

Charlotte Douglas

mar. 2/17

5:54 pm-8:58 am

1 stop15h 04m

$177

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mié. 2/18

6:15 am-1:43 pm

1 stop7h 28m

Charlotte Douglas

mié. 2/18

7:13 pm-8:13 am

1 stop13h 00m

$186

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

sáb. 2/28

11:57 am-8:26 am

2 stops20h 29m

Charlotte Douglas

dom. 3/1

9:07 pm-8:58 am

1 stop11h 51m

$190

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mié. 2/25

10:09 am-8:12 pm

1 stop10h 03m

Charlotte Douglas

mié. 3/4

9:21 am-8:13 am

3 stops22h 52m

$190

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mar. 2/24

10:09 am-11:56 pm

2 stops13h 47m

Charlotte Douglas

mar. 3/3

1:24 pm-2:55 pm

3 stops25h 31m

$201

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mié. 2/11

8:15 pm-8:13 am

2 stops11h 58m

Charlotte Douglas

sáb. 2/14

5:54 pm-8:39 pm

1 stop26h 45m

$206

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

mié. 4/15

7:51 pm-12:40 am

1 stop4h 49m

Charlotte Douglas

jue. 4/16

6:30 am-11:48 am

1 stop5h 18m

$206

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 19 results
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Best time to book a flight from Myrtle Beach to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spartanburg

What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $166). Flying from Myrtle Beach to Spartanburg in November is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SB1?

Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 29, 2026.

One of the essential ways to save on airfare from Myrtle Beach to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 62% on airfare.

What is the cheapest day to fly from Myrtle Beach to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Myrtle Beach to Spartanburg

Explore weekly flight availability from Myrtle Beach to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated enero 29, 2026.

The most flights from MYR to SB1 are scheduled on a Thursday (9 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (6 on average).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated enero 29, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,205 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,205 reviews
American Airlines
7.2
Good
11,205 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spartanburg?

    For a flight from Myrtle Beach to Spartanburg, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city. Myrtle Beach Intl is the only Myrtle Beach airport and it handles 8 outbound flights to Spartanburg per day. 1 airline has flights to Spartanburg from Myrtle Beach Intl on a regular basis.

  • How popular is this Myrtle Beach to Spartanburg flight route?

    Flights from Myrtle Beach Intl to Spartanburg have been viewed 25 times in the past calendar month.

  • What are the most reliable airlines from Myrtle Beach to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from Myrtle Beach to Spartanburg consider choosing PSA Airlines (85%), American Airlines (82%) or Envoy Air (78%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Myrtle Beach to Spartanburg?

    On average you can expect to pay $954 for a flight from Myrtle Beach to Spartanburg. The cheapest flight overall is $100 while the most popular route, (Myrtle Beach Intl - Charlotte Douglas) is currently priced at $181.

  • Can I find deals for flights from Myrtle Beach to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spartanburg.

  • Can I find deals for business class flights from Myrtle Beach to Spartanburg?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $166). Flying from Myrtle Beach to Spartanburg in November is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Myrtle Beach to Spartanburg

Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$369FlexibilityNo cancel feeOn-time71%

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