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$89+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Spartanburg

Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$178
(Cheapflightsfares)

One-way from

$89
(Cheapflightsfares)

Popular in

March

Cheapest in

January

Average price

$551
Provider with most accurate pricing for Myrtle Beach Intl-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Charlotte Douglas flights.
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From Myrtle Beach Intl to Spartanburg
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One-way flight from Myrtle Beach Intl to Spartanburg
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Highest demand for flights based on searches. 11% potential increase in price ($52 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Myrtle Beach to Spartanburg

Cheapest flights from Myrtle Beach to Spartanburg
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:46 amMYR - CLT
1 stop7h 04mSpirit Airlines
Fri 12/58:55 amCLT - MYR
1 stop8h 53mSpirit Airlines
Deal found 10/30$178
This Cheapflightsfares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:15 amMYR - CLT
1 stop7h 51mSpirit Airlines
Mon 11/245:59 pmCLT - MYR
1 stop5h 55mSpirit Airlines
Deal found 10/28$188
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:15 amMYR - CLT
1 stop10h 58mMultiple Airlines
Wed 12/310:17 amCLT - MYR
1 stop9h 37mMultiple Airlines
Deal found 10/30$205
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:46 pmMYR - CLT
1 stop4h 55mSpirit Airlines
Mon 12/88:10 pmCLT - MYR
1 stop12h 39mSpirit Airlines
Deal found 10/30$206
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:15 amMYR - CLT
2 stops15h 41mMultiple Airlines
Mon 11/172:35 pmCLT - MYR
1 stop23h 16mMultiple Airlines
Deal found 10/29$207
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:15 amMYR - CLT
1 stop13h 42mSpirit Airlines
Thu 12/48:55 amCLT - MYR
1 stop8h 53mSpirit Airlines
Deal found 10/28$208
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:22 amMYR - CLT
1 stop5h 25mMultiple Airlines
Wed 12/310:17 amCLT - MYR
1 stop9h 37mMultiple Airlines
Deal found 10/30$209
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:46 pmMYR - CLT
1 stop4h 55mSpirit Airlines
Sun 12/78:55 amCLT - MYR
1 stop8h 53mSpirit Airlines
Deal found 10/30$211
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:22 amMYR - CLT
1 stop5h 25mMultiple Airlines
Mon 12/88:10 pmCLT - MYR
1 stop12h 39mMultiple Airlines
Deal found 10/30$212
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:15 amMYR - CLT
1 stop10h 58mMultiple Airlines
Sun 12/78:55 amCLT - MYR
1 stop8h 53mMultiple Airlines
Deal found 10/30$213
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:13 amMYR - CLT
1 stop8h 45mMultiple Airlines
Mon 11/172:35 pmCLT - MYR
1 stop23h 16mMultiple Airlines
Deal found 10/29$214

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.

Fly from

Myrtle Beach

Fly to

Spartanburg

Route

Depart

Return

Price

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 12/3

9:46 am-4:50 pm

1 stop7h 04m

Charlotte Douglas

Fri 12/5

8:55 am-5:48 pm

1 stop8h 53m

$178

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 12/1

6:15 am-5:13 pm

1 stop10h 58m

Charlotte Douglas

Wed 12/3

10:17 am-7:54 pm

1 stop9h 37m

$205

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 11/13

6:15 am-9:56 pm

2 stops15h 41m

Charlotte Douglas

Mon 11/17

2:35 pm-1:51 pm

1 stop23h 16m

$207

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Tue 12/2

9:22 am-2:47 pm

1 stop5h 25m

Charlotte Douglas

Wed 12/3

10:17 am-7:54 pm

1 stop9h 37m

$209

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 12/3

1:46 pm-6:41 pm

1 stop4h 55m

Charlotte Douglas

Sun 12/7

8:55 am-5:48 pm

1 stop8h 53m

$211

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 12/1

6:15 am-5:13 pm

1 stop10h 58m

Charlotte Douglas

Tue 12/2

10:45 am-8:03 pm

1 stop9h 18m

$211

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 12/4

9:54 am-11:59 pm

1 stop14h 05m

Charlotte Douglas

Fri 12/5

8:55 am-5:48 pm

1 stop8h 53m

$213

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 12/1

6:15 am-5:13 pm

1 stop10h 58m

Charlotte Douglas

Fri 12/5

8:55 am-5:48 pm

1 stop8h 53m

$213

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 11/12

11:13 am-7:58 pm

1 stop8h 45m

Charlotte Douglas

Mon 11/17

2:35 pm-1:51 pm

1 stop23h 16m

$214

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Tue 12/2

9:22 am-2:47 pm

1 stop5h 25m

Charlotte Douglas

Fri 12/5

8:55 am-5:48 pm

1 stop8h 53m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 21 results
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Best time to book a flight from Myrtle Beach to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spartanburg

What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $191). Flying from Myrtle Beach to Spartanburg in April is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SB1?

Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 51% on airfare.

What is the cheapest day to fly from Myrtle Beach to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,034 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,034 reviews
American Airlines
7.2
Good
11,034 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spartanburg?

    For a flight from Myrtle Beach to Spartanburg, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city. Myrtle Beach Intl is the only Myrtle Beach airport and it handles 2 outbound flights to Spartanburg per day. 1 airline has flights to Spartanburg from Myrtle Beach Intl on a regular basis.

  • How popular is this Myrtle Beach to Spartanburg flight route?

    Flights from Myrtle Beach Intl to Spartanburg have been viewed 2 times in the past calendar month.

  • How long is the flight from Myrtle Beach to Spartanburg?

    There are many flights that can get you from Myrtle Beach to Spartanburg in 7h 04m. Fly via Spirit Airlines to get the fastest option. Airlines will cover a distance of 157 mi.

  • What are the most reliable airlines from Myrtle Beach to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from Myrtle Beach to Spartanburg consider choosing Envoy Air (100%), PSA Airlines (89%) or American Airlines (86%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Myrtle Beach to Spartanburg?

    On average you can expect to pay $679 for a flight from Myrtle Beach to Spartanburg. The cheapest flight overall is $138 while the most popular route, (Myrtle Beach Intl - Charlotte Douglas) is currently priced at $188.

  • Can I find deals for flights from Myrtle Beach to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spartanburg.

  • Can I find deals for business class flights from Myrtle Beach to Spartanburg?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

    Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $191). Flying from Myrtle Beach to Spartanburg in April is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Myrtle Beach to Spartanburg

Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$343FlexibilityNo cancel feeOn-time71%

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