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Spartanburg

$83+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
Apr 28 — May 51
Tue 4/28
Tue 5/5
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Spartanburg

Cheapest flights from Myrtle Beach to Spartanburg
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.

This Spirit deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:52 am
MYR
-
CLT
1 stop8h 57m
Spirit Airlines
Sat 5/22:59 pm
CLT
-
MYR
1 stop8h 30m
Spirit Airlines
Deal found 3/26$177
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:23 pm
MYR
-
CLT
1 stop6h 29m
Multiple Airlines
Sun 4/269:54 pm
CLT
-
MYR
1 stop25h 35m
Multiple Airlines
Deal found 3/27$185
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:52 am
MYR
-
CLT
1 stop8h 57m
Spirit Airlines
Fri 5/112:50 pm
CLT
-
MYR
1 stop10h 39m
Spirit Airlines
Deal found 3/25$187
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:52 am
MYR
-
CLT
1 stop8h 57m
Spirit Airlines
Tue 4/219:54 pm
CLT
-
MYR
1 stop18h 37m
Spirit Airlines
Deal found 3/24$192
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:28 pm
MYR
-
CLT
1 stop14h 42m
Spirit Airlines
Tue 4/219:54 pm
CLT
-
MYR
1 stop18h 37m
Spirit Airlines
Deal found 3/24$193
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 am
MYR
-
CLT
1 stop11h 41m
Spirit Airlines
Sat 4/182:59 pm
CLT
-
MYR
1 stop8h 30m
Spirit Airlines
Deal found 3/24$196
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:23 pm
MYR
-
CLT
1 stop7h 38m
Spirit Airlines
Tue 4/219:54 pm
CLT
-
MYR
1 stop18h 37m
Spirit Airlines
Deal found 3/24$197
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:52 am
MYR
-
CLT
1 stop8h 57m
Spirit Airlines
Tue 4/219:54 pm
CLT
-
MYR
1 stop18h 37m
Spirit Airlines
Deal found 3/24$199
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:43 pm
MYR
-
CLT
1 stop22h 31m
Multiple Airlines
Fri 4/248:56 am
CLT
-
MYR
1 stop14h 33m
Multiple Airlines
Deal found 3/24$203
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:23 pm
MYR
-
CLT
1 stop7h 38m
Multiple Airlines
Fri 4/248:56 am
CLT
-
MYR
1 stop14h 33m
Multiple Airlines
Deal found 3/24$204

Find flight deals from Myrtle Beach to Spartanburg

Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated March 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$177
(Spirit)

One-way from

$83
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$334
Provider with most accurate pricing for Myrtle Beach Intl-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Charlotte Douglas flights.
Search Deals
From Myrtle Beach Intl to Spartanburg
Search Deals
One-way flight from Myrtle Beach Intl to Spartanburg
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($144 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 4/24

11:52 am-8:49 pm

1 stop8h 57m

Charlotte Douglas

Fri 5/1

12:50 pm-11:29 pm

1 stop10h 39m

$177

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 6/24

10:25 am-8:20 pm

2 stops9h 55m

Charlotte Douglas

Tue 6/30

1:25 pm-9:10 pm

2 stops7h 45m

$387

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 6/22

2:00 pm-11:15 pm

2 stops9h 15m

Charlotte Douglas

Wed 6/24

1:25 pm-8:30 pm

2 stops7h 05m

$387

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Tue 4/14

11:15 am-8:45 pm

2 stops9h 30m

Charlotte Douglas

Fri 4/17

6:15 am-3:10 pm

2 stops8h 55m

$420
Quickest round-trip

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 5/28

10:00 am-3:09 pm

1 stop5h 09m

Charlotte Douglas

Sun 5/31

6:15 am-2:12 pm

1 stop7h 57m

$485

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 5/14

11:30 am-5:11 pm

1 stop5h 41m

Charlotte Douglas

Sun 5/17

6:15 am-2:18 pm

1 stop8h 03m

$485

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 4/16

11:00 am-5:24 pm

1 stop6h 24m

Charlotte Douglas

Sun 4/19

6:15 am-2:17 pm

1 stop8h 02m

$513

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Tue 4/14

5:55 pm-10:06 am

2 stops16h 11m

Charlotte Douglas

Tue 4/21

7:30 pm-2:17 pm

2 stops18h 47m

$552

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 4/15

5:55 pm-10:06 am

2 stops16h 11m

Charlotte Douglas

Tue 4/21

7:30 pm-2:17 pm

2 stops18h 47m

$568
Cheapest one-way

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Tue 6/9

11:52 am-8:19 pm

1 stop8h 27m

$86

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Myrtle Beach to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spartanburg

What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $154). Flying from Myrtle Beach to Spartanburg in November is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SB1?

Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 29, 2026.

One of the essential ways to save on airfare from Myrtle Beach to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 61% on airfare.

What is the cheapest day to fly from Myrtle Beach to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on March 28, 2026.

Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Myrtle Beach to Spartanburg?

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated March 29, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,521 reviews

Comfort

7.2

Overall

7.1

Crew

7.9

Food

6.4

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,521 reviews
American Airlines
7.1
Good
11,521 reviews

Comfort

7.2

Overall

7.1

Crew

7.9

Food

6.4

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spartanburg?

    For a flight from Myrtle Beach to Spartanburg, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city. Myrtle Beach Intl is the only Myrtle Beach airport and it handles 6 outbound flights to Spartanburg per day. 1 airline has flights to Spartanburg from Myrtle Beach Intl on a regular basis.

  • How popular is this Myrtle Beach to Spartanburg flight route?

    Flights from Myrtle Beach Intl to Spartanburg have been viewed 41 times in the past calendar month.

  • How long is the flight from Myrtle Beach to Spartanburg?

    There are many flights that can get you from Myrtle Beach to Spartanburg in 5h 09m. Fly via Spirit Airlines, Southwest, or United Airlines to get the fastest option. Airlines will cover a distance of 157 mi. This flight may include one or multiple stops.

  • What are the most reliable airlines from Myrtle Beach to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from Myrtle Beach to Spartanburg consider choosing Piedmont Airlines (75%), British Airways (73%) or Envoy Air (72%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Myrtle Beach to Spartanburg?

    On average you can expect to pay $751 for a flight from Myrtle Beach to Spartanburg. The cheapest flight overall is $143 while the most popular route, (Myrtle Beach Intl - Charlotte Douglas) is currently priced at $177.

  • Can I find deals for flights from Myrtle Beach to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spartanburg.

  • Can I find deals for business class flights from Myrtle Beach to Spartanburg?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Spartanburg?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Spartanburg (average of $154). Flying from Myrtle Beach to Spartanburg in November is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Myrtle Beach to Spartanburg

Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$391FlexibilityNo cancel feeOn-time71%

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