$121+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
Oct 4 — Oct 111
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Spartanburg
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Cheapest flights from Myrtle Beach to SpartanburgExplore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:10 pm -
1 stop21h 40m
Wed 9/238:05 pm -
Nonstop1h 03m
Deal found 8/31![American Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:55 am -
1 stop18h 32m
Fri 10/167:35 am -
Nonstop1h 02m
Deal found 8/31![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:41 pm -
1 stop17h 54m
Wed 9/309:32 am -
1 stop23h 18m
Deal found 9/1![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:46 pm -
1 stop17h 51m
Mon 11/26:05 am -
1 stop28h 00m
Deal found 8/31![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:41 pm -
1 stop17h 56m
Sat 10/175:37 pm -
1 stop15h 10m
Deal found 9/4![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:35 pm -
1 stop18h 02m
Sat 11/75:37 pm -
1 stop15h 14m
Deal found 8/31![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:32 am -
1 stop23h 00m
Fri 10/165:38 pm -
1 stop15h 30m
Deal found 8/31![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/112:46 pm -
1 stop17h 51m
Fri 10/165:38 pm -
1 stop15h 30m
Deal found 8/31![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:41 pm -
1 stop17h 54m
Sun 9/205:38 pm -
1 stop14h 20m
Deal found 8/30![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:02 pm -
1 stop16h 33m
Wed 9/235:37 pm -
1 stop15h 15m
Deal found 8/31![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:02 pm -
1 stop16h 33m
Tue 10/65:37 pm -
2 stops42h 37m
Deal found 9/1![Multiple Airlines logo]()
$357
Best flights from Myrtle Beach to SpartanburgDiscover carefully curated flight deals from Myrtle Beach to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from Myrtle Beach to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:41 pm -
1 stop17h 54m
Sun 9/205:38 pm -
1 stop14h 20m
Deal found 8/30![Multiple Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:23 am -
1 stop10h 32m
Mon 10/58:54 pm -
1 stop14h 31m
Deal found 9/3![American Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 pm -
1 stop4h 00m
Sun 10/256:35 am -
1 stop6h 00m
Deal found 9/3![Southwest logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:12 pm -
2 stops14h 20m
Sun 10/255:38 pm -
1 stop14h 20m
Deal found 8/30![Multiple Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:35 am -
1 stop7h 05m
Wed 12/2312:35 pm -
1 stop6h 05m
Deal found 8/30![Southwest logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:19 pm -
1 stop12h 31m
Wed 9/3010:20 am -
Nonstop1h 00m
Deal found 9/1![American Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:20 pm -
2 stops6h 35m
Wed 9/306:50 am -
2 stops7h 00m
Deal found 9/1![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:25 am -
2 stops9h 55m
Sun 10/256:35 am -
2 stops8h 50m
Deal found 8/30![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:25 pm -
1 stop4h 40m
Wed 9/236:50 am -
2 stops7h 00m
Deal found 8/31![Southwest logo]()
$475
Last-minute flights from Myrtle Beach to SpartanburgDiscover last-minute flight deals from Myrtle Beach to Spartanburg. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Spartanburg. Data last updated September 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:41 pm -
1 stop17h 54m
Sun 9/205:38 pm -
1 stop14h 20m
Deal found 8/30![Multiple Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:10 pm -
1 stop21h 40m
Wed 9/238:05 pm -
Nonstop1h 03m
Deal found 8/31![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:02 pm -
1 stop16h 33m
Wed 9/235:37 pm -
1 stop15h 15m
Deal found 8/31![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:41 pm -
1 stop17h 54m
Wed 9/309:32 am -
1 stop23h 18m
Deal found 9/1![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:02 pm -
1 stop16h 33m
Tue 10/65:37 pm -
2 stops42h 37m
Deal found 9/1![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/112:46 pm -
1 stop17h 51m
Fri 10/165:38 pm -
1 stop15h 30m
Deal found 8/31![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:41 pm -
1 stop17h 56m
Sat 10/175:37 pm -
1 stop15h 10m
Deal found 9/4![Multiple Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:55 am -
1 stop18h 32m
Fri 10/167:35 am -
Nonstop1h 02m
Deal found 8/31![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:32 am -
1 stop23h 00m
Fri 10/165:38 pm -
1 stop15h 30m
Deal found 8/31![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:41 pm -
1 stop17h 16m
Sun 10/255:38 pm -
1 stop14h 20m
Deal found 8/30![Multiple Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:46 pm -
1 stop17h 51m
Mon 11/26:05 am -
1 stop28h 00m
Deal found 8/31![Multiple Airlines logo]()
$325
One-way flights from Myrtle Beach to SpartanburgSearch for one-way flight options from Myrtle Beach to Spartanburg. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from Myrtle Beach to Spartanburg. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:58 pm -
1 stop20h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:12 pm -
2 stops25h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/30![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:12 pm -
2 stops25h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:02 pm -
1 stop23h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:03 pm -
1 stop25h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:02 pm -
1 stop16h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$147
Find flight deals from Myrtle Beach to Spartanburg
Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated September 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (American Airlines) |
One-way from | $121 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Fri 10/30
6:12 pm-7:13 pm
2 stops25h 01m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$138
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Thu 10/29
9:36 am-10:40 am
1 stop25h 04m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
Quickest round-trip
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Sat 10/31
1:10 pm-5:00 pm
1 stop3h 50m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$204
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Wed 3/3
3:40 pm-7:55 pm
1 stop4h 15m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$204
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Tue 3/2
3:40 pm-7:55 pm
1 stop4h 15m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$204
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Mon 11/2
10:45 am-7:25 pm
2 stops8h 40m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Sun 2/28
1:45 pm-9:55 pm
1 stop8h 10m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Thu 12/3
10:45 am-8:00 pm
2 stops9h 15m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Mon 3/1
1:40 pm-9:05 pm
1 stop7h 25m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Myrtle BeachCharlotte
MYR Myrtle Beach Intl - CLT Charlotte Douglas
MYRCLT
Myrtle Beach Intl
Wed 12/2
2:35 pm-8:44 pm
1 stop6h 09m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$226
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Myrtle Beach to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
MYR-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Spartanburg
MYR-SB1
MYR-CLT
What is the cheapest time of day to fly from MYR to SB1?
Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 4, 2026.
One of the essential ways to save on airfare from Myrtle Beach to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 29% on airfare.
What is the cheapest day to fly from Myrtle Beach to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on August 29, 2026.
Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated September 4, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Crew
7.9
Boarding
7.5
Entertainment
6.8
Overall
7.1
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Comfort
7.2
Crew
7.9
Boarding
7.5
Entertainment
6.8
Overall
7.1
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Myrtle Beach and Spartanburg flights
Browse other Myrtle Beach and Spartanburg flight options. Last updated on September 4, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on September 4, 2026.
Popular flight searches
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Myrtle Beach to Spartanburg flights
Consider these flights traveling from Myrtle Beach to Spartanburg.
Top airline flying from Myrtle Beach to Spartanburg
Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$356 | Average$483 | FlexibilityNo cancel fee | On-time71% |