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$100+ Cheap flights from Myrtle Beach (MYR) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CLT
Jun 21 — Jun 281
Sun 6/21
Sun 6/28
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Spartanburg

Cheapest flights from Myrtle Beach to Spartanburg
Explore the most affordable flight options available from Myrtle Beach to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.

This Mytrip deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:30 pm
MYR
-
CLT
1 stop17h 30m
Contour
Sat 6/2011:55 am
CLT
-
MYR
1 stop3h 45m
Contour
Deal found 5/20$199
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:42 am
MYR
-
CLT
2 stops24h 20m
Multiple Airlines
Thu 7/166:41 pm
CLT
-
MYR
1 stop15h 09m
Multiple Airlines
Deal found 5/19$285
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:28 pm
MYR
-
CLT
2 stops18h 23m
Multiple Airlines
Sat 6/1311:55 am
CLT
-
MYR
1 stop3h 45m
Multiple Airlines
Deal found 5/21$333
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:18 pm
MYR
-
CLT
1 stop15h 45m
Multiple Airlines
Tue 6/165:45 pm
CLT
-
MYR
1 stop21h 55m
Multiple Airlines
Deal found 5/19$339
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:28 pm
MYR
-
CLT
1 stop21h 06m
Multiple Airlines
Wed 6/2411:55 am
CLT
-
MYR
1 stop3h 45m
Multiple Airlines
Deal found 5/20$341
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:42 pm
MYR
-
CLT
2 stops18h 00m
Multiple Airlines
Sat 6/2011:55 am
CLT
-
MYR
1 stop3h 45m
Multiple Airlines
Deal found 5/20$360
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/64:30 pm
MYR
-
CLT
1 stop17h 30m
Multiple Airlines
Mon 8/310:04 pm
CLT
-
MYR
2 stops35h 01m
Multiple Airlines
Deal found 5/19$371
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:00 pm
MYR
-
CLT
1 stop4h 30m
Southwest
Sun 7/56:00 pm
CLT
-
MYR
1 stop4h 45m
Southwest
Deal found 5/18$377
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:00 pm
MYR
-
CLT
2 stops9h 15m
Southwest
Wed 6/2411:50 am
CLT
-
MYR
2 stops9h 20m
Southwest
Deal found 5/20$387

Find flight deals from Myrtle Beach to Spartanburg

Keep the following information in mind while searching for Myrtle Beach to Spartanburg flight deals. Data was last updated May 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$198
(Booking.com)

One-way from

$100
(Booking.com)

Popular in

March

Cheapest in

February

Average price

$401
Provider with most accurate pricing for Myrtle Beach Intl-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Charlotte Douglas flights.
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From Myrtle Beach Intl to Spartanburg
Search Deals
One-way flight from Myrtle Beach Intl to Spartanburg
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Spartanburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 7/31

2:00 pm-6:30 pm

1 stop4h 30m

Charlotte Douglas

Fri 8/7

7:40 am-1:50 pm

1 stop6h 10m

$377
Quickest round-trip

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 7/3

2:00 pm-6:30 pm

1 stop4h 30m

Charlotte Douglas

Sun 7/5

1:05 pm-7:05 pm

1 stop6h 00m

$377

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 7/9

10:35 am-6:30 pm

2 stops7h 55m

Charlotte Douglas

Thu 7/16

11:35 am-7:30 pm

2 stops7h 55m

$387

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 6/22

2:00 pm-11:15 pm

2 stops9h 15m

Charlotte Douglas

Wed 6/24

11:50 am-9:10 pm

2 stops9h 20m

$387

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 6/15

2:00 pm-11:15 pm

2 stops9h 15m

Charlotte Douglas

Sun 6/21

6:00 pm-10:45 pm

1 stop4h 45m

$393

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Wed 6/17

10:25 am-7:40 pm

2 stops9h 15m

Charlotte Douglas

Sat 6/20

1:00 pm-9:05 pm

2 stops8h 05m

$398

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 7/17

2:00 pm-11:15 pm

2 stops9h 15m

Charlotte Douglas

Mon 7/20

11:35 am-7:30 pm

2 stops7h 55m

$398

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 6/15

2:00 pm-6:30 pm

1 stop4h 30m

Charlotte Douglas

Tue 6/16

3:10 pm-9:45 pm

1 stop6h 35m

$399

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 6/18

2:00 pm-6:30 pm

1 stop4h 30m

Charlotte Douglas

Fri 6/19

6:35 am-1:25 pm

1 stop6h 50m

$399
Cheapest one-way

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Sat 6/13

4:30 pm-5:05 pm

1 stop24h 35m

$114

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/19

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Myrtle Beach to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Spartanburg

What is the cheapest time of day to fly from MYR to SB1?

Find hourly flight availability from Myrtle Beach to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 22, 2026.

One of the essential ways to save on airfare from Myrtle Beach to Spartanburg is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 24% on airfare.

Weekly flight availability from Myrtle Beach to Spartanburg

Explore weekly flight availability from Myrtle Beach to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 22, 2026.

The most flights from MYR to SB1 are scheduled on a Monday (10 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Myrtle Beach to Spartanburg?

What is the cheapest day to fly from Myrtle Beach to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Spartanburg. Price data was last updated on May 16, 2026.

Travelers seeking maximum savings on their Myrtle Beach to Spartanburg flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated May 22, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,644 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.1

Crew

7.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,644 reviews
American Airlines
7.1
Good
11,644 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.1

Crew

7.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Spartanburg?

    For a flight from Myrtle Beach to Spartanburg, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city. Myrtle Beach Intl is the only Myrtle Beach airport and it handles 7 outbound flights to Spartanburg per day. 1 airline has flights to Spartanburg from Myrtle Beach Intl on a regular basis.

  • How popular is this Myrtle Beach to Spartanburg flight route?

    Flights from Myrtle Beach Intl to Spartanburg have been viewed 49 times in the past calendar month.

  • How long is the flight from Myrtle Beach to Spartanburg?

    There are many flights that can get you from Myrtle Beach to Spartanburg in 4h 30m. Fly via Southwest to get the fastest option. Airlines will cover a distance of 157 mi.

  • What are the most reliable airlines from Myrtle Beach to Spartanburg?

    No one likes to see their flight delayed. When booking a flight from Myrtle Beach to Spartanburg consider choosing PSA Airlines (90%), American Airlines (90%) or British Airways (82%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Myrtle Beach to Spartanburg?

    On average you can expect to pay $1,167 for a flight from Myrtle Beach to Spartanburg. The cheapest flight overall is $156 while the most popular route, (Myrtle Beach Intl - Charlotte Douglas) is currently priced at $199.

  • Can I find deals for flights from Myrtle Beach to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Spartanburg.

  • Can I find deals for business class flights from Myrtle Beach to Spartanburg?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Myrtle Beach to Spartanburg

Discover the top airline that operate flights from Myrtle Beach to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$281Average$427FlexibilityNo cancel feeOn-time71%

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