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Spartanburg

$86+ Cheap flights from Milwaukee (MKE) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CLT
Apr 1 — Apr 81
Wed 4/1
Wed 4/8
1 adult, Economy
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Cheapflights Tip: The best prices from Milwaukee-Mitchell to Spartanburg are usually found in April or June, booked 34 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Milwaukee to Spartanburg

Cheapest flights from Milwaukee to Spartanburg
Explore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 2, 2026.

This Expedia deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:35 pm
MKE
-
CLT
1 stop12h 28m
Frontier
Wed 3/111:59 pm
CLT
-
MKE
1 stop18h 31m
Frontier
Deal found 2/26$202
This Expedia deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:01 pm
MKE
-
CLT
1 stop9h 57m
Frontier
Mon 3/239:28 pm
CLT
-
MKE
1 stop21h 22m
Frontier
Deal found 2/28$224
This Priceline deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:01 pm
MKE
-
CLT
1 stop9h 57m
Frontier
Thu 3/262:32 pm
CLT
-
MKE
1 stop6h 34m
Frontier
Deal found 3/1$230
This Frontier deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:01 pm
MKE
-
CLT
1 stop10h 59m
Frontier
Mon 3/232:32 pm
CLT
-
MKE
1 stop6h 03m
Frontier
Deal found 2/26$244
This Expedia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:01 pm
MKE
-
CLT
1 stop9h 57m
Frontier
Sun 3/298:13 pm
CLT
-
MKE
1 stop13h 43m
Frontier
Deal found 3/1$250
This Frontier deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:01 pm
MKE
-
CLT
1 stop9h 57m
Frontier
Wed 3/119:08 am
CLT
-
MKE
1 stop9h 42m
Frontier
Deal found 2/27$251
This Frontier deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:20 pm
MKE
-
CLT
1 stop10h 43m
Frontier
Wed 3/259:08 am
CLT
-
MKE
1 stop9h 42m
Frontier
Deal found 2/27$264
This Frontier deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:01 pm
MKE
-
CLT
1 stop9h 57m
Frontier
Sat 3/219:28 pm
CLT
-
MKE
1 stop11h 02m
Frontier
Deal found 2/28$265
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:11 am
MKE
-
CLT
1 stop10h 25m
American Airlines
Tue 4/211:05 pm
CLT
-
MKE
1 stop8h 01m
American Airlines
Deal found 2/26$267
This Expedia deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:47 pm
MKE
-
CLT
1 stop14h 29m
Frontier
Sun 3/227:48 pm
CLT
-
MKE
1 stop16h 53m
Frontier
Deal found 2/28$270
This Frontier deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:37 pm
MKE
-
CLT
1 stop11h 26m
Frontier
Wed 3/119:08 am
CLT
-
MKE
1 stop9h 42m
Frontier
Deal found 2/28$271

Find flight deals from Milwaukee to Spartanburg

Keep the following information in mind while searching for Milwaukee to Spartanburg flight deals. Data was last updated March 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$224
(Expedia)

One-way from

$86
(Expedia)

Popular in

February

Cheapest in

April

Average price

$439
Provider with most accurate pricing for Milwaukee-Mitchell-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Charlotte Douglas flights.
Search Deals
From Milwaukee-Mitchell to Spartanburg
Search Deals
One-way flight from Milwaukee-Mitchell to Spartanburg
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Milwaukee to Spartanburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 4/18

5:40 am-11:35 am

1 stop4h 55m

Charlotte Douglas

Wed 4/22

1:45 pm-9:45 pm

2 stops9h 00m

$286

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 6/13

12:20 pm-8:21 pm

1 stop7h 01m

Charlotte Douglas

Sat 6/20

10:07 am-4:16 pm

1 stop7h 09m

$357

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 5/27

8:00 am-4:10 pm

2 stops7h 10m

Charlotte Douglas

Tue 6/2

7:35 am-4:15 pm

2 stops9h 40m

$367

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 6/20

6:05 am-2:11 pm

2 stops7h 06m

Charlotte Douglas

Wed 6/24

6:15 am-9:57 am

1 stop4h 42m

$372

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 5/29

10:53 am-8:22 pm

1 stop8h 29m

Charlotte Douglas

Sun 5/31

8:05 am-12:48 pm

1 stop5h 43m

$417

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 5/29

5:23 am-11:06 am

1 stop4h 43m

Charlotte Douglas

Sun 5/31

5:35 am-9:08 am

1 stop4h 33m

$417

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 4/24

1:55 pm-9:28 pm

1 stop6h 33m

Charlotte Douglas

Sun 4/26

5:30 am-9:05 am

1 stop4h 35m

$417

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 6/26

1:30 pm-9:29 pm

1 stop6h 59m

Charlotte Douglas

Sun 6/28

8:05 am-12:48 pm

1 stop5h 43m

$417

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 6/5

7:00 am-3:25 pm

1 stop7h 25m

Charlotte Douglas

Mon 6/8

4:00 pm-10:55 pm

2 stops7h 55m

$422

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 4/10

12:13 pm-5:24 pm

1 stop4h 11m

Charlotte Douglas

Sun 4/12

6:00 am-1:47 pm

2 stops8h 47m

$422

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/26

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Milwaukee to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Spartanburg

How far ahead should I book a flight from Milwaukee to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Milwaukee to Spartanburg. Price data was last updated on February 27, 2026.

The price you pay for your flight from Milwaukee to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Milwaukee to Spartanburg?

Currently, December is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $56). Flying from Milwaukee to Spartanburg in June is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SB1?

Find hourly flight availability from Milwaukee to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 2, 2026.

One of the essential ways to save on airfare from Milwaukee to Spartanburg is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 36% on airfare.

What is the cheapest day to fly from Milwaukee to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Milwaukee to Spartanburg. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Milwaukee to Spartanburg flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated March 2, 2026.
See what other customers who have flown with Southwest, Delta, and American Airlines from Milwaukee to Spartanburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,306 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.
Southwest
8.0
Very good
4,306 reviews
Southwest
8.0
Very good
4,306 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.
Delta
7.9
Good
8,237 reviews
Southwest
8.0
Very good
4,306 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.
American Airlines
7.1
Good
11,369 reviews
Southwest
8.0
Very good
4,306 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to Spartanburg?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to Spartanburg. 4 airlines have flights from Milwaukee-Mitchell to Spartanburg on a regular basis. Booking flights from Milwaukee-Mitchell to Spartanburg should not be difficult; the airport handles an average of 1 outbound flight to Spartanburg per day.

  • How popular is this Milwaukee to Spartanburg flight route?

    Flights from Milwaukee-Mitchell to Spartanburg have been viewed 13 times in the past calendar month.

  • How long is the flight from Milwaukee to Spartanburg?

    Southwest, Delta, and United Airlines can get you from Milwaukee to Spartanburg in just under 4h 55m. Your travel time can differ by up to 2h 11m. The distance from Milwaukee to Spartanburg is about 650 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest flights from Milwaukee to Spartanburg?

    While on average a flight from Milwaukee to Spartanburg is generally $337, our data shows the cheapest flight currently is $123. When looking at the most popular route, (Milwaukee-Mitchell - Charlotte Douglas), you can expect to pay $294 for that flight.

  • Can I find deals for flights from Milwaukee to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Spartanburg.

  • Can I find deals for business class flights from Milwaukee to Spartanburg?

    Yes. Cheapflights offers flight deals from Milwaukee to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Spartanburg?

    Currently, December is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $56). Flying from Milwaukee to Spartanburg in June is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Milwaukee to Spartanburg

Discover the top 4 airlines that operate flights from Milwaukee to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$104Average$314FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$371FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$227Average$370FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$294Average$418FlexibilityNo cancel feeOn-time63%

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