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$75+ Cheap flights from Milwaukee (MKE) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CLT
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Cheapflights Tip: The best prices from Milwaukee-Mitchell to Spartanburg are usually found in April or December, booked 37 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Milwaukee to Spartanburg

Keep the following information in mind while searching for Milwaukee to Spartanburg flight deals. Data was last updated November 17, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$194
(Kiwi.com)

One-way from

$75
(Frontier)

Popular in

February

Cheapest in

April

Average price

$447
Provider with most accurate pricing for Milwaukee-Mitchell-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Charlotte Douglas flights.
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From Milwaukee-Mitchell to Spartanburg
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One-way flight from Milwaukee-Mitchell to Spartanburg
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Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Milwaukee to Spartanburg

Cheapest flights from Milwaukee to Spartanburg
Explore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Expedia deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:21 pmMKE - CLT
1 stop23h 48mFrontier
Sun 12/219:33 pmCLT - MKE
1 stop14h 40mFrontier
Deal found 11/16$198
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:48 pmMKE - CLT
1 stop16h 49mMultiple Airlines
Wed 12/249:04 pmCLT - MKE
1 stop23h 16mMultiple Airlines
Deal found 11/14$249
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:48 pmMKE - CLT
1 stop16h 49mMultiple Airlines
Thu 12/259:34 pmCLT - MKE
1 stop20h 47mMultiple Airlines
Deal found 11/14$261
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:15 pmMKE - CLT
1 stop22h 54mMultiple Airlines
Wed 12/249:04 pmCLT - MKE
1 stop23h 16mMultiple Airlines
Deal found 11/14$272
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:48 pmMKE - CLT
1 stop16h 49mMultiple Airlines
Mon 12/299:43 pmCLT - MKE
1 stop22h 37mMultiple Airlines
Deal found 11/14$277
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:15 pmMKE - CLT
1 stop16h 41mMultiple Airlines
Thu 12/259:34 pmCLT - MKE
1 stop20h 47mMultiple Airlines
Deal found 11/14$284
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:48 pmMKE - CLT
1 stop16h 49mMultiple Airlines
Sun 12/289:34 pmCLT - MKE
2 stops13h 19mMultiple Airlines
Deal found 11/14$286
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:21 pmMKE - CLT
1 stop18h 40mMultiple Airlines
Sun 12/219:00 amCLT - MKE
2 stops11h 20mMultiple Airlines
Deal found 11/16$298

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Milwaukee to Spartanburg that are best for you.

Fly from

Milwaukee

Fly to

Spartanburg

Route

Depart

Return

Price

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 12/17

10:54 am-5:20 pm

1 stop5h 26m

Charlotte Douglas

Tue 12/30

11:02 am-5:07 pm

1 stop7h 05m

$359

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 12/17

5:45 am-10:45 am

1 stop4h 00m

Charlotte Douglas

Thu 12/25

10:04 am-2:53 pm

1 stop5h 49m

$359

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 12/24

5:40 am-1:46 pm

1 stop7h 06m

Charlotte Douglas

Tue 12/30

6:00 am-8:49 am

1 stop3h 49m

$359

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 12/25

8:15 pm-8:09 pm

1 stop22h 54m

Charlotte Douglas

Sun 12/28

9:34 pm-9:53 am

2 stops13h 19m

$380

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 12/19

4:52 pm-9:55 pm

1 stop4h 03m

Charlotte Douglas

Wed 12/31

6:00 am-9:33 am

1 stop4h 33m

$395

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sun 12/14

11:41 am-6:28 pm

1 stop5h 47m

Charlotte Douglas

Sat 12/27

6:00 am-9:31 am

1 stop4h 31m

$395

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 12/22

3:38 pm-10:11 pm

1 stop5h 33m

Charlotte Douglas

Tue 12/30

9:46 am-1:17 pm

1 stop4h 31m

$395

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 12/17

5:45 am-10:45 am

1 stop4h 00m

Charlotte Douglas

Mon 12/29

6:00 am-9:33 am

1 stop4h 33m

$395

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sun 12/21

7:00 am-12:25 pm

1 stop4h 25m

Charlotte Douglas

Tue 12/30

6:00 am-9:33 am

1 stop4h 33m

$395

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 1/1

5:40 am-1:46 pm

1 stop7h 06m

Charlotte Douglas

Sun 1/4

1:05 pm-5:15 pm

1 stop5h 10m

$396

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 20 results
1
2

Best time to book a flight from Milwaukee to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Spartanburg

How far ahead should I book a flight from Milwaukee to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Milwaukee to Spartanburg. Price data was last updated on November 14, 2025.

The price you pay for your flight from Milwaukee to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 37 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Milwaukee to Spartanburg?

Currently, February is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $51). Flying from Milwaukee to Spartanburg in April is currently the most expensive (average of $127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SB1?

Find hourly flight availability from Milwaukee to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

One of the essential ways to save on airfare from Milwaukee to Spartanburg is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 23% on airfare.

What is the cheapest day to fly from Milwaukee to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Milwaukee to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Milwaukee to Spartanburg flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Milwaukee to Spartanburg?

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated November 17, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Milwaukee to Spartanburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,008 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,048 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,145 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,103 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to Spartanburg?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to Spartanburg. 6 airlines have flights from Milwaukee-Mitchell to Spartanburg on a regular basis. Booking flights from Milwaukee-Mitchell to Spartanburg should not be difficult; the airport handles an average of 2 outbound flights to Spartanburg per day.

  • How popular is this Milwaukee to Spartanburg flight route?

    Flights from Milwaukee-Mitchell to Spartanburg have been viewed 4 times in the past calendar month.

  • How long is the flight from Milwaukee to Spartanburg?

    United Airlines and Delta can get you from Milwaukee to Spartanburg in just under 4h. Your travel time can differ by up to 1h 26m. The distance from Milwaukee to Spartanburg is about 650 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest flights from Milwaukee to Spartanburg?

    While on average a flight from Milwaukee to Spartanburg is generally $336, our data shows the cheapest flight currently is $131. When looking at the most popular route, (Milwaukee-Mitchell - Charlotte Douglas), you can expect to pay $277 for that flight.

  • Can I find deals for flights from Milwaukee to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Spartanburg.

  • Can I find deals for business class flights from Milwaukee to Spartanburg?

    Yes. Cheapflights offers flight deals from Milwaukee to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Spartanburg?

    Currently, February is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $51). Flying from Milwaukee to Spartanburg in April is currently the most expensive (average of $127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Milwaukee to Spartanburg

Discover the top 6 airlines that operate flights from Milwaukee to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$128FlexibilityNo cancel feeOn-time62%
DeltaCheapest$123Average$331FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$139Average$238FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$227Average$394FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$227Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$294Average$418FlexibilityNo cancel feeOn-time63%

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