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Spartanburg

$68+ Cheap flights from Milwaukee (MKE) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CLT
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheapflights Tip: The best prices from Milwaukee-Mitchell to Spartanburg are usually found in April or June, booked 34 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Milwaukee to Spartanburg

Keep the following information in mind while searching for Milwaukee to Spartanburg flight deals. Data was last updated January 7, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$128
(Frontier)

One-way from

$68
(Kiwi.com)

Popular in

January

Cheapest in

April

Average price

$479
Provider with most accurate pricing for Milwaukee-Mitchell-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Charlotte Douglas flights.
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From Milwaukee-Mitchell to Spartanburg
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One-way flight from Milwaukee-Mitchell to Spartanburg
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Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Milwaukee to Spartanburg

Cheapest flights from Milwaukee to Spartanburg
Explore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This Frontier deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:48 pmMKE - CLT
1 stop12h 42mFrontier
Tue 2/311:35 amCLT - MKE
1 stop7h 23mFrontier
Deal found 1/6$128
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/276:53 pmMKE - CLT
1 stop21h 01mMultiple Airlines
Mon 2/27:50 pmCLT - MKE
1 stop23h 08mMultiple Airlines
Deal found 1/6$131
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:01 pmMKE - CLT
1 stop14h 39mFrontier
Wed 2/112:46 pmCLT - MKE
1 stop17h 54mFrontier
Deal found 1/6$135
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:01 pmMKE - CLT
1 stop14h 39mFrontier
Fri 2/69:59 pmCLT - MKE
1 stop13h 18mFrontier
Deal found 1/6$142
This Frontier deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:35 pmMKE - CLT
1 stop12h 28mFrontier
Sat 3/149:28 pmCLT - MKE
1 stop11h 02mFrontier
Deal found 1/7$150
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:01 pmMKE - CLT
1 stop14h 39mMultiple Airlines
Wed 2/117:43 pmCLT - MKE
2 stops12h 57mMultiple Airlines
Deal found 1/6$151
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:01 pmMKE - CLT
1 stop14h 39mFrontier
Thu 2/121:17 pmCLT - MKE
1 stop21h 26mFrontier
Deal found 1/6$159
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:48 pmMKE - CLT
1 stop13h 29mMultiple Airlines
Mon 2/29:56 pmCLT - MKE
1 stop21h 02mMultiple Airlines
Deal found 1/7$164
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:48 pmMKE - CLT
1 stop12h 42mFrontier
Wed 2/112:46 pmCLT - MKE
1 stop17h 54mFrontier
Deal found 1/6$170
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/77:48 pmMKE - CLT
1 stop13h 29mMultiple Airlines
Wed 2/117:43 pmCLT - MKE
2 stops12h 57mMultiple Airlines
Deal found 1/6$175
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:48 pmMKE - CLT
2 stops24h 59mMultiple Airlines
Tue 2/311:35 amCLT - MKE
1 stop7h 23mMultiple Airlines
Deal found 1/6$178

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Milwaukee to Spartanburg that are best for you.

Fly from

Milwaukee

Fly to

Spartanburg

Route

Depart

Return

Price

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 4/18

5:40 am-3:10 pm

2 stops8h 30m

Charlotte Douglas

Wed 4/22

7:35 am-10:55 am

1 stop4h 20m

$299

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Fri 2/20

11:22 am-2:40 pm

Nonstop2h 18m

Charlotte Douglas

Mon 2/23

10:48 pm-7:49 am

1 stop10h 01m

$321

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 4/22

2:45 pm-8:45 pm

1 stop5h 00m

Charlotte Douglas

Mon 4/27

8:25 pm-11:25 pm

1 stop4h 00m

$324

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 2/4

5:30 am-12:40 pm

2 stops6h 10m

Charlotte Douglas

Mon 2/9

5:50 am-11:30 am

2 stops6h 40m

$335

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 4/18

9:35 am-4:09 pm

1 stop5h 34m

Charlotte Douglas

Sat 4/25

6:00 am-8:50 am

1 stop3h 50m

$337

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Tue 4/21

5:05 pm-9:34 pm

1 stop3h 29m

Charlotte Douglas

Sat 4/25

5:11 pm-8:50 pm

1 stop4h 39m

$337

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 6/13

2:45 pm-9:05 pm

1 stop5h 20m

Charlotte Douglas

Sat 6/20

5:30 am-9:23 am

1 stop4h 53m

$337

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 2/19

8:00 am-4:42 pm

1 stop7h 42m

Charlotte Douglas

Sun 2/22

7:45 am-11:56 am

1 stop5h 11m

$347

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Tue 1/27

5:30 am-12:40 pm

2 stops6h 10m

Charlotte Douglas

Mon 2/2

7:45 am-7:55 pm

2 stops13h 10m

$359

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 4/20

5:05 pm-9:34 pm

1 stop3h 29m

Charlotte Douglas

Sat 4/25

6:00 am-8:50 am

1 stop3h 50m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Showing 1-10 of 23 results
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Best time to book a flight from Milwaukee to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Spartanburg

How far ahead should I book a flight from Milwaukee to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Milwaukee to Spartanburg. Price data was last updated on January 2, 2026.

The price you pay for your flight from Milwaukee to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Milwaukee to Spartanburg?

Currently, February is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $51). Flying from Milwaukee to Spartanburg in April is currently the most expensive (average of $127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SB1?

Find hourly flight availability from Milwaukee to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 7, 2026.

One of the essential ways to save on airfare from Milwaukee to Spartanburg is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 36% on airfare.

What is the cheapest day to fly from Milwaukee to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Milwaukee to Spartanburg. Price data was last updated on January 3, 2026.

Travelers seeking maximum savings on their Milwaukee to Spartanburg flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated January 7, 2026.
See what other customers who have flown with Southwest, Delta, and American Airlines from Milwaukee to Spartanburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,025 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,095 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to Spartanburg?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to Spartanburg. 4 airlines have flights from Milwaukee-Mitchell to Spartanburg on a regular basis. Booking flights from Milwaukee-Mitchell to Spartanburg should not be difficult; the airport handles an average of 1 outbound flight to Spartanburg per day.

  • How popular is this Milwaukee to Spartanburg flight route?

    Flights from Milwaukee-Mitchell to Spartanburg have been viewed 10 times in the past calendar month.

  • How long is the flight from Milwaukee to Spartanburg?

    Southwest and American Airlines can get you from Milwaukee to Spartanburg in just under 2h 18m. Your travel time can differ by up to 6h 12m. The distance from Milwaukee to Spartanburg is about 650 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest flights from Milwaukee to Spartanburg?

    While on average a flight from Milwaukee to Spartanburg is generally $340, our data shows the cheapest flight currently is $162. When looking at the most popular route, (Milwaukee-Mitchell - Charlotte Douglas), you can expect to pay $131 for that flight.

  • Can I find deals for flights from Milwaukee to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Spartanburg.

  • Can I find deals for business class flights from Milwaukee to Spartanburg?

    Yes. Cheapflights offers flight deals from Milwaukee to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Spartanburg?

    Currently, February is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $51). Flying from Milwaukee to Spartanburg in April is currently the most expensive (average of $127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Milwaukee to Spartanburg

Discover the top 4 airlines that operate flights from Milwaukee to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$123Average$335FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$227Average$380FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$227Average$358FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$370Average$418FlexibilityNo cancel feeOn-time63%

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