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Spartanburg

$124+ Cheap flights from Milwaukee (MKE) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CLT
Nov 1 — Nov 81
Sat 11/1
Sat 11/8
1 adult, Economy
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Cheapflights Tip: The best prices from Milwaukee-Mitchell to Spartanburg are usually found in April or December, booked 37 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Milwaukee to Spartanburg

Keep the following information in mind while searching for Milwaukee to Spartanburg flight deals. Data was last updated October 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$245
(Frontier)

One-way from

$124
(American Airlines)

Popular in

February

Cheapest in

April

Average price

$411
Provider with most accurate pricing for Milwaukee-Mitchell-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Charlotte Douglas flights.
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From Milwaukee-Mitchell to Spartanburg
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One-way flight from Milwaukee-Mitchell to Spartanburg
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Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Milwaukee to Spartanburg

Cheapest flights from Milwaukee to Spartanburg
Explore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2025.

This Frontier deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:04 pmMKE - CLT
2 stops13h 08mFrontier
Sun 11/169:20 pmCLT - MKE
2 stops22h 59mFrontier
Deal found 9/29$245
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/218:00 amMKE - CLT
Nonstop2h 06mAmerican Airlines
Tue 10/2810:06 pmCLT - MKE
Nonstop2h 10mAmerican Airlines
Deal found 9/30$247
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:12 amMKE - CLT
Nonstop2h 06mAmerican Airlines
Wed 10/2910:06 pmCLT - MKE
Nonstop2h 10mAmerican Airlines
Deal found 10/2$266
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2112:06 pmMKE - CLT
1 stop5h 24mDelta
Tue 10/286:45 amCLT - MKE
1 stop5h 16mDelta
Deal found 9/30$267
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/215:45 amMKE - CLT
2 stops6h 40mSouthwest
Tue 10/284:20 pmCLT - MKE
1 stop7h 05mSouthwest
Deal found 9/30$272
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:35 amMKE - CLT
2 stops9h 00mSouthwest
Wed 11/512:55 pmCLT - MKE
1 stop9h 35mSouthwest
Deal found 9/29$278
This Frontier deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:04 pmMKE - CLT
2 stops13h 08mFrontier
Sun 11/29:20 pmCLT - MKE
2 stops22h 59mFrontier
Deal found 9/29$282
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/283:06 pmMKE - CLT
Nonstop2h 09mAmerican Airlines
Sat 11/810:53 pmCLT - MKE
Nonstop2h 09mAmerican Airlines
Deal found 9/30$284
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:29 amMKE - CLT
Nonstop2h 11mAmerican Airlines
Thu 11/204:54 pmCLT - MKE
Nonstop2h 07mAmerican Airlines
Deal found 10/1$285
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:44 pmMKE - CLT
1 stop4h 06mDelta
Wed 10/299:32 amCLT - MKE
1 stop3h 53mDelta
Deal found 10/2$286

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Milwaukee to Spartanburg that are best for you.

Fly from

Milwaukee

Fly to

Spartanburg

Route

Depart

Return

Price

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Wed 10/29

7:35 am-5:35 pm

2 stops9h 00m

Charlotte Douglas

Wed 11/5

12:55 pm-9:30 pm

1 stop9h 35m

$278

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 10/23

10:35 am-4:40 pm

1 stop5h 05m

Charlotte Douglas

Mon 10/27

5:05 pm-8:42 pm

1 stop4h 37m

$305

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 11/6

5:00 am-12:15 pm

1 stop6h 15m

Charlotte Douglas

Sat 11/8

6:45 am-9:55 am

1 stop4h 10m

$318

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Tue 12/2

4:05 pm-9:10 pm

1 stop4h 05m

Charlotte Douglas

Fri 12/5

5:10 pm-8:20 pm

1 stop4h 10m

$320

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sat 10/25

7:16 am-12:11 pm

1 stop3h 55m

Charlotte Douglas

Mon 10/27

5:05 pm-8:42 pm

1 stop4h 37m

$323

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 10/27

1:20 pm-11:20 pm

1 stop9h 00m

Charlotte Douglas

Wed 10/29

12:55 pm-10:25 pm

2 stops10h 30m

$333

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 12/4

4:05 pm-9:10 pm

1 stop4h 05m

Charlotte Douglas

Sun 12/7

6:55 pm-11:25 pm

1 stop5h 30m

$339

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Sun 11/9

5:00 am-12:15 pm

1 stop6h 15m

Charlotte Douglas

Wed 11/12

6:20 pm-9:45 pm

1 stop4h 25m

$342

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Mon 11/17

6:00 am-7:55 pm

2 stops12h 55m

Charlotte Douglas

Thu 11/20

10:50 am-9:45 pm

2 stops11h 55m

$344

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

Thu 11/13

7:03 pm-9:02 am

1 stop12h 59m

$132

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/2

Showing 1-10 of 19 results
1
2

Best time to book a flight from Milwaukee to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Spartanburg

How far ahead should I book a flight from Milwaukee to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Milwaukee to Spartanburg. Price data was last updated on September 26, 2025.

The price you pay for your flight from Milwaukee to Spartanburg may vary depending on when you book. For the best chance of a lower fare, look to book 37 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Milwaukee to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $248). Flying from Milwaukee to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SB1?

Find hourly flight availability from Milwaukee to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Milwaukee to Spartanburg as you normally would.

What is the cheapest day to fly from Milwaukee to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Milwaukee to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Milwaukee to Spartanburg flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated October 2, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Milwaukee to Spartanburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,962 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,033 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,070 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,155 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to Spartanburg?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to Spartanburg. 6 airlines have flights from Milwaukee-Mitchell to Spartanburg on a regular basis. Booking flights from Milwaukee-Mitchell to Spartanburg should not be difficult; the airport handles an average of 1 outbound flight to Spartanburg per day.

  • How popular is this Milwaukee to Spartanburg flight route?

    Flights from Milwaukee-Mitchell to Spartanburg have been viewed 2 times in the past calendar month.

  • How long is the flight from Milwaukee to Spartanburg?

    United Airlines and Southwest can get you from Milwaukee to Spartanburg in just under 7h 10m. Your travel time can differ by up to 1h 50m. The distance from Milwaukee to Spartanburg is about 650 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest flights from Milwaukee to Spartanburg?

    While on average a flight from Milwaukee to Spartanburg is generally $457, our data shows the cheapest flight currently is $110. When looking at the most popular route, (Milwaukee-Mitchell - Charlotte Douglas), you can expect to pay $267 for that flight.

  • Can I find deals for flights from Milwaukee to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Spartanburg.

  • Can I find deals for business class flights from Milwaukee to Spartanburg?

    Yes. Cheapflights offers flight deals from Milwaukee to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to Spartanburg (average of $248). Flying from Milwaukee to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Milwaukee to Spartanburg

Discover the top 6 airlines that operate flights from Milwaukee to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$128FlexibilityNo cancel feeOn-time62%
DeltaCheapest$123Average$338FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$139Average$238FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$227Average$366FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$274Average$365FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$359Average$418FlexibilityNo cancel feeOn-time63%

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