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$457+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated July 1, 2025.

Round-trip from

$457
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$996
From Knoxville McGhee Tyson to Spain
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($285 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($50 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/297:15 amTYS - BCN
1 stop24h 20mMultiple Airlines
Mon 10/136:30 pmBCN - TYS
1 stop23h 25mMultiple Airlines
Deal found 7/1$457
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/187:00 amTYS - MAD
2 stops41h 40mUnited Airlines
Fri 12/121:35 pmMAD - TYS
2 stops29h 42mUnited Airlines
Deal found 6/29$564
This Booking.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:45 amTYS - MAD
2 stops20h 15mAir Canada
Wed 11/191:35 pmMAD - TYS
2 stops16h 24mAir Canada
Deal found 6/29$578
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:45 amTYS - BCN
2 stops21h 50mUnited Airlines
Thu 11/1310:30 amBCN - TYS
1 stop15h 50mUnited Airlines
Deal found 6/29$583
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:20 pmTYS - MAD
2 stops16h 30mMultiple Airlines
Fri 11/141:35 pmMAD - TYS
2 stops31h 13mMultiple Airlines
Deal found 6/30$586
This British Airways deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:54 pmTYS - MAD
2 stops15h 51mBritish Airways
Fri 11/141:15 pmMAD - TYS
1 stop13h 21mBritish Airways
Deal found 6/30$591
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:47 amTYS - MAD
2 stops17h 13mDelta
Wed 11/1210:00 amMAD - TYS
2 stops16h 39mDelta
Deal found 6/29$592
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:23 pmTYS - BCN
2 stops14h 22mAmerican Airlines
Thu 11/1310:35 amBCN - TYS
2 stops16h 01mAmerican Airlines
Deal found 6/29$603
This Travelocity deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/293:13 pmTYS - BCN
1 stop13h 17mBritish Airways
Mon 10/138:25 pmBCN - TYS
2 stops50h 13mBritish Airways
Deal found 7/1$613
This Lufthansa deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:20 pmTYS - MAD
2 stops16h 30mLufthansa
Thu 11/135:55 amMAD - TYS
2 stops24h 04mLufthansa
Deal found 6/30$616
This KLM deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:00 pmTYS - MAD
1 stop11h 00mKLM
Tue 11/1111:00 amMAD - TYS
1 stop13h 13mKLM
Deal found 6/29$662
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:10 pmTYS - AGP
2 stops16h 25mDelta
Tue 11/1812:40 pmAGP - TYS
2 stops35h 33mDelta
Deal found 6/28$684

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Mon 9/29

7:15 am-1:35 pm

1 stop24h 20m

Barcelona-El Prat

Mon 10/13

6:30 pm-11:55 am

1 stop23h 25m

$457

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 8/18

7:00 am-6:40 am

2 stops41h 40m

Madrid Barajas

Fri 12/12

1:35 pm-1:17 pm

2 stops29h 42m

$564

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 11/11

5:45 am-8:00 am

2 stops20h 15m

Madrid Barajas

Wed 11/19

1:35 pm-11:59 pm

2 stops16h 24m

$578

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Tue 11/4

5:45 am-9:35 am

2 stops21h 50m

Barcelona-El Prat

Thu 11/13

10:30 am-8:20 pm

1 stop15h 50m

$583

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

7:20 pm-5:50 pm

2 stops16h 30m

Madrid Barajas

Fri 11/14

1:35 pm-2:48 pm

2 stops31h 13m

$586

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 8/18

7:10 am-9:35 am

1 stop20h 25m

Madrid Barajas

Wed 12/10

11:00 am-6:13 pm

1 stop13h 13m

$587

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

6:54 pm-4:45 pm

2 stops15h 51m

Madrid Barajas

Fri 11/14

1:15 pm-8:36 pm

1 stop13h 21m

$591

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Tue 11/4

6:23 pm-2:45 pm

2 stops14h 22m

Barcelona-El Prat

Thu 11/13

10:35 am-8:36 pm

2 stops16h 01m

$603

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Mon 9/29

3:13 pm-10:30 am

1 stop13h 17m

Barcelona-El Prat

Mon 10/13

8:25 pm-4:38 pm

2 stops50h 13m

$613

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

7:20 pm-5:50 pm

2 stops16h 30m

Madrid Barajas

Thu 11/13

5:55 am-11:59 pm

2 stops24h 04m

$616

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 20 results
1
2

Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ES?

Find hourly flight availability from Knoxville to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

When flying from Knoxville to Spain, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated July 1, 2025.
See what other customers who have flown with Delta, KLM, and United Airlines from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,366 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Virgin Atlantic
7.4
Good
654 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Madrid Barajas. You may also consider Knoxville McGhee Tyson - Barcelona-El Prat or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Knoxville to Spain

Discover the top 5 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$530Average$828FlexibilityNo cancel feeOn-time75%
DeltaCheapest$530Average$1,054FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$562Average$960FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$586Average$1,122FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$594Average$909FlexibilityNo cancel feeOn-time70%

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