What are the cheapest airlines flying from Knoxville to Madrid round-trip?

According to our current data, American Airlines ($592), United Airlines ($593), and Delta ($611) offers the cheapest pricing from Knoxville to Madrid. American Airlines is currently priced 42% below the average price you’ll pay for this route.

What is the cheapest day to fly from Knoxville to Madrid?

Travelers seeking maximum savings on their Knoxville to Madrid flight should consider departing on Thursday afternoons when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Madrid ranges from 0.4 - 2.4 inches per month. November is typically the wettest month, when rainfall can reach 2.4 in. July is typically the driest time to visit Madrid when rainfall is around 0.4 in.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the most popular airlines that fly from Knoxville to Madrid?

The most popular airlines flying from Knoxville to Madrid are American Airlines, British Airways and United Airlines. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Knoxville to Madrid?

Users have found that leaving on a Sunday can be a cost-effective option. It’s possible to save up to 49% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Knoxville to Madrid?

Our data shows that November tends to be the cheapest month to fly to Madrid from Knoxville. Users have commonly found prices around $1,030 for the month, but tickets can be as low as $534. Due to multiple factors, prepare for potentially higher prices in June.

Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Madrid?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

Can I find deals for business class flights from Knoxville to Madrid?

Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$561+ Flights from Knoxville to Madrid, Spain

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Cheap flight deals from Knoxville to Madrid

Round-trip from	$561 (Mytrip)
Popular in	June
Cheapest in	November
Average price	$1,021

From Knoxville McGhee Tyson to Madrid Barajas

Search Deals

Highest demand for flights based on searches. 22% potential increase in price ($293 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Tue 11/115:45 amTYS - MAD

2 stops20h 15mMultiple Airlines

Wed 11/195:55 amMAD - TYS

2 stops24h 04mMultiple Airlines

Deal found 7/2

$561

Tue 11/1110:16 amTYS - MAD

1 stop15h 39mAmerican Airlines

Wed 11/1912:30 pmMAD - TYS

2 stops15h 02mAmerican Airlines

Deal found 7/2

$592

Sat 11/87:20 pmTYS - MAD

1 stop30h 45mUnited Airlines

Wed 11/191:35 pmMAD - TYS

2 stops16h 24mUnited Airlines

Deal found 7/1

$593

Mon 11/1012:00 pmTYS - MAD

1 stop15h 00mDelta

Wed 11/196:00 amMAD - TYS

2 stops22h 59mDelta

Deal found 6/30

$611

Wed 11/57:20 pmTYS - MAD

2 stops22h 15mLufthansa

Tue 11/186:05 amMAD - TYS

2 stops20h 15mLufthansa

Deal found 7/2

$616

Thu 11/64:00 pmTYS - MAD

1 stop11h 00mVirgin Atlantic

Tue 11/1110:00 amMAD - TYS

2 stops17h 32mVirgin Atlantic

Deal found 7/1

$642

Sat 11/87:20 pmTYS - MAD

2 stops30h 40mAir Canada

Sun 11/161:35 pmMAD - TYS

2 stops27h 13mAir Canada

Deal found 7/1

$649

Thu 10/23:13 pmTYS - MAD

1 stop16h 12mBritish Airways

Sat 10/115:25 pmMAD - TYS

2 stops29h 12mBritish Airways

Deal found 7/2

$708

Fri 11/710:50 amTYS - MAD

1 stop16h 10mKLM

Mon 11/171:00 pmMAD - TYS

2 stops16h 46mKLM

Deal found 7/1

$726

Best flights from Knoxville to Madrid
Discover carefully curated flight deals from Knoxville to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Tue 11/115:45 amTYS - MAD

2 stops20h 15mMultiple Airlines

Wed 11/195:55 amMAD - TYS

2 stops24h 04mMultiple Airlines

Deal found 7/2

$561

Tue 11/1110:16 amTYS - MAD

1 stop15h 39mAmerican Airlines

Wed 11/1912:30 pmMAD - TYS

2 stops15h 02mAmerican Airlines

Deal found 7/2

$592

Sat 11/87:20 pmTYS - MAD

1 stop30h 45mUnited Airlines

Wed 11/191:35 pmMAD - TYS

2 stops16h 24mUnited Airlines

Deal found 7/1

$593

Mon 11/1012:00 pmTYS - MAD

1 stop15h 00mDelta

Wed 11/196:00 amMAD - TYS

2 stops22h 59mDelta

Deal found 6/30

$611

Wed 11/57:20 pmTYS - MAD

2 stops16h 30mLufthansa

Thu 11/135:55 amMAD - TYS

2 stops24h 04mLufthansa

Deal found 7/1

$616

Thu 11/64:00 pmTYS - MAD

1 stop11h 00mVirgin Atlantic

Tue 11/1110:00 amMAD - TYS

2 stops17h 32mVirgin Atlantic

Deal found 7/1

$642

Sat 11/87:20 pmTYS - MAD

2 stops30h 40mAir Canada

Sun 11/161:35 pmMAD - TYS

2 stops27h 13mAir Canada

Deal found 7/1

$649

Thu 10/23:13 pmTYS - MAD

1 stop16h 12mBritish Airways

Sat 10/115:25 pmMAD - TYS

2 stops29h 12mBritish Airways

Deal found 7/2

$708

Fri 11/710:50 amTYS - MAD

1 stop16h 10mKLM

Mon 11/171:00 pmMAD - TYS

2 stops16h 46mKLM

Deal found 7/1

$726

Last-minute flights from Knoxville to Madrid
Discover last-minute flight deals from Knoxville to Madrid. Data last updated July 2, 2025 and is based on user searches.

Tue 7/155:46 pmTYS - MAD

2 stops22h 39mLufthansa

Mon 8/411:45 amMAD - TYS

2 stops16h 50mLufthansa

Deal found 7/1

$5,788

Tue 7/2210:59 amTYS - MAD

1 stop16h 36mKLM

Thu 7/317:05 amMAD - TYS

2 stops16h 27mKLM

Deal found 7/1

$1,001

Tue 7/228:08 amTYS - MAD

2 stops19h 47mAer Lingus

Sat 7/2611:35 amMAD - TYS

1 stop15h 57mAer Lingus

Deal found 7/2

$1,675

Tue 7/221:54 pmTYS - MAD

1 stop12h 01mAmerican Airlines

Sat 7/261:00 pmMAD - TYS

1 stop12h 42mAmerican Airlines

Deal found 7/2

$1,802

Fri 8/17:05 amTYS - MAD

1 stop20h 30mDelta

Fri 8/86:00 amMAD - TYS

2 stops17h 32mDelta

Deal found 7/2

$906

Sat 8/165:45 amTYS - MAD

2 stops18h 55mMultiple Airlines

Sat 8/236:00 amMAD - TYS

2 stops23h 57mMultiple Airlines

Deal found 7/2

$774

Sat 8/161:53 pmTYS - MAD

1 stop13h 42mVirgin Atlantic

Sat 8/2310:05 amMAD - TYS

1 stop13h 04mVirgin Atlantic

Deal found 7/2

$777

Sat 8/165:45 amTYS - MAD

3 stops18h 55mAir Canada

Sat 8/2312:45 pmMAD - TYS

3 stops17h 12mAir Canada

Deal found 7/2

$941

Wed 8/279:30 amTYS - MAD

2 stops17h 30mUnited Airlines

Sat 12/208:25 amMAD - TYS

2 stops31h 20mUnited Airlines

Deal found 6/30

$899

Wed 8/2710:55 amTYS - MAD

1 stop16h 40mBritish Airways

Sat 12/207:40 amMAD - TYS

2 stops19h 04mBritish Airways

Deal found 6/30

$903

Wed 8/272:23 pmTYS - MAD

1 stop12h 42mFinnair

Sat 12/2011:30 amMAD - TYS

1 stop18h 19mFinnair

Deal found 6/30

$1,007

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 11/11

5:45 am-8:00 am

2 stops20h 15m

Madrid Barajas

Wed 11/19

5:55 am-11:59 pm

2 stops24h 04m

$561

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 11/11

10:16 am-7:55 am

1 stop15h 39m

Madrid Barajas

Wed 11/19

12:30 pm-9:32 pm

2 stops15h 02m

$592

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 11/8

7:20 pm-8:05 am

1 stop30h 45m

Madrid Barajas

Wed 11/19

1:35 pm-11:59 pm

2 stops16h 24m

$593

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 11/10

12:00 pm-9:00 am

1 stop15h 00m

Madrid Barajas

Wed 11/19

6:00 am-10:59 pm

2 stops22h 59m

$611

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

7:20 pm-11:35 pm

2 stops22h 15m

Madrid Barajas

Thu 11/13

5:55 am-11:59 pm

2 stops24h 04m

$616

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 11/6

4:00 pm-9:00 am

1 stop11h 00m

Madrid Barajas

Tue 11/11

10:00 am-9:32 pm

2 stops17h 32m

$642

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 11/8

7:20 pm-8:00 am

2 stops30h 40m

Madrid Barajas

Sun 11/16

1:35 pm-10:48 am

2 stops27h 13m

$649

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 10/2

3:13 pm-1:25 pm

1 stop16h 12m

Madrid Barajas

Sat 10/11

5:25 pm-4:37 pm

2 stops29h 12m

$708

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 11/7

10:50 am-9:00 am

1 stop16h 10m

Madrid Barajas

Mon 11/17

1:00 pm-11:46 pm

2 stops16h 46m

$726

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $543). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MAD?

Unlike in the evening, when flights are generally more expensive, you can save up to 25% on flights from Knoxville to Madrid by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Knoxville to Madrid?

Reviews of airlines servicing Madrid

See what other customers who have flown with Delta, KLM, and United Airlines from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,975 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

KLM

7.8

Good

1,366 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Virgin Atlantic

7.4

Good

654 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Knoxville to Madrid round-trip?
According to our current data, American Airlines ($592), United Airlines ($593), and Delta ($611) offers the cheapest pricing from Knoxville to Madrid. American Airlines is currently priced 42% below the average price you’ll pay for this route.
Can I find deals for flights from Knoxville to Madrid that include hotel bookings?
Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Madrid?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.
Can I find deals for business class flights from Knoxville to Madrid?
Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Madrid?
Currently, November is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $543). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Segovia

Fuenlabrada

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Knoxville to Madrid

Nashville to Madrid flights

Memphis to Madrid flights

Other flights to Madrid

Top 3 airlines flying from Knoxville to Madrid

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$562	Average$881	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$586	Average$1,139	FlexibilityNo cancel fee	On-time71%
British Airways	Cheapest$594	Average$800	FlexibilityNo cancel fee	On-time70%

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$561+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Madrid with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Madrid

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to MadridExplore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

What is the cheapest time of day to fly from TYS to MAD?

Find hourly flight availability from Knoxville to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

How much does it cost to fly round-trip from Knoxville to Madrid?

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated July 2, 2025.

See what other customers who have flown with Delta, KLM, and United Airlines from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to Madrid round-trip?

Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

How can I find direct flights from Knoxville to Madrid?

Can I find deals for business class flights from Knoxville to Madrid?

What is the cheapest month to book a flight from Knoxville to Madrid?

Traveling to a place near Knoxville?

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Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Knoxville to Madrid

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Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.