$407+ Cheap flights from Knoxville (TYS) to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to SpainExplore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:07 pm -
1 stop11h 38m
Tue 12/81:25 pm -
2 stops37h 12m
Deal found 10/17![United Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:34 am -
1 stop15h 16m
Tue 12/810:00 am -
1 stop18h 10m
Deal found 10/17![American Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:07 pm -
1 stop11h 38m
Thu 12/101:25 pm -
2 stops40h 34m
Deal found 10/19![United Airlines logo]()
$789
This KLM deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:10 pm -
2 stops20h 20m
Wed 12/910:40 am -
2 stops16h 53m
Deal found 10/18![KLM logo]()
$790
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:45 am -
1 stop22h 15m
Fri 11/61:35 pm -
2 stops51h 09m
Deal found 10/20![United Airlines logo]()
$796
This FlightHub deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:06 pm -
2 stops23h 24m
Fri 11/612:00 pm -
1 stop14h 49m
Deal found 10/16![British Airways logo]()
$802
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:27 am -
1 stop14h 18m
Thu 12/1012:00 pm -
1 stop17h 26m
Deal found 10/19![American Airlines logo]()
$809
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:32 pm -
2 stops16h 58m
Thu 12/106:05 am -
2 stops21h 28m
Deal found 10/19![Delta logo]()
$813
This Cheapflightsfares deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
2 stops21h 00m
Wed 11/116:50 am -
2 stops23h 09m
Deal found 10/18![Lufthansa logo]()
$836
This United deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
1 stop32h 35m
Wed 11/111:35 pm -
2 stops55h 13m
Deal found 10/18![Multiple Airlines logo]()
$846
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop21h 05m
Wed 11/1111:00 am -
1 stop17h 01m
Deal found 10/18![American Airlines logo]()
$855
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
1 stop17h 15m
Sun 12/2011:00 am -
2 stops30h 04m
Deal found 10/15![United Airlines logo]()
$859
Best flights from Knoxville to SpainDiscover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/112:20 pm -
2 stops39h 15m
Fri 2/51:35 pm -
2 stops36h 16m
Deal found 10/16![Air Canada logo]()
$717
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/112:20 pm -
1 stop14h 00m
Fri 2/511:00 am -
2 stops29h 10m
Deal found 10/15![United Airlines logo]()
$738
This KLM deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:32 pm -
2 stops15h 28m
Wed 12/98:15 pm -
2 stops31h 18m
Deal found 10/18![KLM logo]()
$869
This FlightHub deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/103:50 pm -
2 stops15h 25m
Sat 1/161:45 pm -
2 stops39h 06m
Deal found 10/18![British Airways logo]()
$948
This Ovago deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:38 pm -
3 stops57h 52m
Thu 12/109:40 pm -
2 stops28h 36m
Deal found 10/19![Multiple Airlines logo]()
$1,194
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:10 am -
1 stop21h 20m
Thu 1/211:25 pm -
2 stops40h 34m
Deal found 10/19![United Airlines logo]()
$738
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:46 pm -
1 stop14h 44m
Wed 12/91:25 pm -
2 stops36h 22m
Deal found 10/18![United Airlines logo]()
$739
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:20 am -
2 stops19h 25m
Tue 12/81:25 pm -
2 stops33h 35m
Deal found 10/17![United Airlines logo]()
$743
This Ovago deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:46 pm -
2 stops43h 24m
Thu 12/108:25 am -
2 stops21h 01m
Deal found 10/19![British Airways logo]()
$1,066
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:45 am -
1 stop17h 15m
Thu 12/1711:00 am -
2 stops19h 15m
Deal found 10/15![United Airlines logo]()
$809
This KAYAK deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1012:02 pm -
2 stops41h 43m
Sat 1/1612:55 pm -
2 stops37h 59m
Deal found 10/18![British Airways logo]()
$1,101
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
1 stop17h 15m
Sun 12/2011:00 am -
2 stops30h 04m
Deal found 10/15![United Airlines logo]()
$859
This British Airways deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:50 am -
2 stops27h 00m
Fri 11/2011:55 am -
2 stops36h 57m
Deal found 10/15![British Airways logo]()
$1,295
Last-minute flights from Knoxville to SpainDiscover last-minute flight deals from Knoxville to Spain. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Spain. Data last updated October 20, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:55 pm -
2 stops31h 35m
Mon 10/2612:30 pm -
2 stops51h 33m
Deal found 10/17![British Airways logo]()
$1,221
This Cheapflightsfares deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
2 stops21h 00m
Wed 11/116:50 am -
2 stops23h 09m
Deal found 10/18![Lufthansa logo]()
$836
This United deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
1 stop32h 35m
Wed 11/111:35 pm -
2 stops55h 13m
Deal found 10/18![Multiple Airlines logo]()
$846
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop21h 05m
Wed 11/1111:00 am -
1 stop17h 01m
Deal found 10/18![American Airlines logo]()
$855
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:45 am -
1 stop22h 15m
Fri 11/61:35 pm -
2 stops51h 09m
Deal found 10/20![United Airlines logo]()
$796
This FlightHub deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:06 pm -
2 stops23h 24m
Fri 11/612:00 pm -
1 stop14h 49m
Deal found 10/16![British Airways logo]()
$802
This Air Canada deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:19 am -
2 stops16h 16m
Fri 11/66:50 am -
3 stops18h 46m
Deal found 10/19![Multiple Airlines logo]()
$1,544
This FlightHub deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:59 pm -
2 stops21h 01m
Mon 11/99:00 pm -
2 stops27h 46m
Deal found 10/15![British Airways logo]()
$890
This Ovago deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:33 am -
1 stop15h 17m
Mon 11/94:30 pm -
1 stop35h 31m
Deal found 10/15![Iberia logo]()
$1,193
This Air Canada deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:35 pm -
2 stops30h 25m
Mon 11/98:35 am -
3 stops21h 24m
Deal found 10/15![Multiple Airlines logo]()
$1,243
This Air Canada deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:45 am -
3 stops16h 15m
Mon 11/98:35 am -
3 stops21h 24m
Deal found 10/15![Air Canada logo]()
$1,770
This British Airways deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:50 am -
2 stops27h 00m
Fri 11/2011:55 am -
2 stops36h 57m
Deal found 10/18![British Airways logo]()
$1,295
One-way flights from Knoxville to SpainSearch for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/127:35 pm -
2 stops16h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$407
This Iberia deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/126:00 am -
1 stop25h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$478
This Cheapflightsfares deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 am -
2 stops22h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Aer Lingus logo]()
$481
This Cheapflightsfares deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:44 am -
2 stops20h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Aer Lingus logo]()
$491
This British Airways deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:17 pm -
1 stop30h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![British Airways logo]()
$565
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:56 pm -
1 stop12h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![British Airways logo]()
$600
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 pm -
1 stop14h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![United Airlines logo]()
$619
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:45 am -
3 stops16h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Air Canada logo]()
$798
This Air Canada deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:45 am -
3 stops17h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Air Canada logo]()
$1,068
Find flight deals from Knoxville to Spain
Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated October 20, 2026.
Round-trip from | $717 (Air Canada) |
|---|---|
One-way from | $407 (United Airlines) |
Popular in | July |
Cheapest in | January |
Average price | $910 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Fri 10/30
7:30 am-10:50 am
2 stops22h 20m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$481
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
7:44 am-9:55 am
2 stops20h 11m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$491
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
5:17 pm-5:45 am
1 stop30h 28m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$565
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Fri 10/30
3:56 pm-9:10 am
1 stop12h 14m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$600
Quickest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Fri 10/23
4:16 pm-9:00 am
1 stop10h 44m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$603
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Fri 10/30
5:40 pm-1:15 pm
1 stop14h 35m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$619
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Mon 2/1
12:20 pm-9:35 am
2 stops39h 15m
Barcelona-El Prat
Fri 2/5
1:35 pm-7:51 pm
2 stops36h 16m
$717
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Mon 2/1
12:20 pm-8:20 am
1 stop14h 00m
Barcelona-El Prat
Fri 2/5
11:00 am-10:10 am
2 stops29h 10m
$738
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 1/17
6:10 am-9:30 am
1 stop21h 20m
Madrid Barajas
Thu 1/21
1:25 pm-11:59 pm
2 stops40h 34m
$738
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Wed 12/2
12:46 pm-9:30 am
1 stop14h 44m
Madrid Barajas
Wed 12/9
1:25 pm-7:47 pm
2 stops36h 22m
$739
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
TYS-MAD
TYS-AGP
TYS-BCN
TYS-SVQ
TYS-GRX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Spain
TYS-ES0
TYS-MAD
TYS-AGP
TYS-BCN
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What is the cheapest month to book a flight from Knoxville to Spain?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Spain (average of $483). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated October 20, 2026.
See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Food
6.7
Overall
7.3
Crew
8.1
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Food
6.7
Overall
7.3
Crew
8.1
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Food
6.7
Overall
7.3
Crew
8.1
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Food
6.7
Overall
7.3
Crew
8.1
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Spain by cabin class
Find flights from Knoxville to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Spain flights
Browse other Knoxville and Spain flight options. Last updated on October 20, 2026.
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Knoxville to Spain flights
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Top 3 airlines flying from Knoxville to Spain
Discover the top 3 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$432 | Average$950 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$591 | Average$829 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$640 | Average$1,069 | FlexibilityNo cancel fee | On-time71% |