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$545+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated April 29, 2025.

Round-trip from

$653
(United Airlines)

One-way from

$545
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$863
From Knoxville McGhee Tyson to Spain
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One-way flight from Knoxville McGhee Tyson to Spain
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 4% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:39 pmTYS - BCN
1 stop13h 26mUnited Airlines
Thu 11/133:05 pmBCN - TYS
1 stop13h 18mUnited Airlines
Deal found 4/29$622
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:55 amTYS - MAD
1 stop16h 10mUnited Airlines
Wed 10/1512:45 pmMAD - TYS
2 stops32h 05mUnited Airlines
Deal found 4/28$653
This Finnair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/101:01 pmTYS - MAD
1 stop12h 54mMultiple Airlines
Wed 10/1511:35 amMAD - TYS
1 stop15h 59mMultiple Airlines
Deal found 4/28$676
This Justfly.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:45 amTYS - BCN
2 stops21h 35mAir Canada
Sun 9/211:15 pmBCN - TYS
2 stops31h 25mAir Canada
Deal found 4/29$722
This Finnair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:27 pmTYS - BCN
1 stop13h 43mMultiple Airlines
Sun 9/216:30 pmBCN - TYS
2 stops25h 27mMultiple Airlines
Deal found 4/29$728
This Justfly.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/234:00 pmTYS - BCN
2 stops20h 10mScandinavian Airlines
Sat 8/307:00 pmBCN - TYS
2 stops34h 29mScandinavian Airlines
Deal found 4/29$732
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2210:05 amTYS - BCN
1 stop15h 10mDelta
Sat 8/309:30 amBCN - TYS
1 stop19h 59mDelta
Deal found 4/29$762
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/137:00 amTYS - AGP
2 stops18h 35mUnited Airlines
Wed 8/209:35 amAGP - TYS
2 stops20h 09mUnited Airlines
Deal found 4/29$789
This British Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:27 pmTYS - MAD
2 stops16h 38mBritish Airways
Thu 5/221:45 pmMAD - TYS
1 stop13h 10mBritish Airways
Deal found 4/28$800
This Gurufare deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/104:02 pmTYS - BCN
1 stop11h 03mBritish Airways
Sun 9/212:00 pmBCN - TYS
1 stop33h 27mBritish Airways
Deal found 4/29$837
This Air Canada deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/225:45 amTYS - MAD
3 stops18h 55mAir Canada
Thu 7/3112:30 pmMAD - TYS
3 stops27h 57mAir Canada
Deal found 4/28$1,069
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2210:53 amTYS - MAD
1 stop16h 42mAmerican Airlines
Thu 7/3111:35 amMAD - TYS
1 stop15h 59mAmerican Airlines
Deal found 4/28$1,081

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 10/10

9:55 am-8:05 am

1 stop16h 10m

Madrid Barajas

Wed 10/15

12:45 pm-2:50 pm

2 stops32h 05m

$653

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 10/10

1:01 pm-7:55 am

1 stop12h 54m

Madrid Barajas

Wed 10/15

11:35 am-9:34 pm

1 stop15h 59m

$676

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/14

6:27 pm-5:05 pm

2 stops16h 38m

Madrid Barajas

Thu 5/22

1:45 pm-8:55 pm

1 stop13h 10m

$800

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 7/22

5:45 am-6:40 am

3 stops18h 55m

Madrid Barajas

Thu 7/31

12:30 pm-10:27 am

3 stops27h 57m

$1,069

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 7/22

10:53 am-9:35 am

1 stop16h 42m

Madrid Barajas

Thu 7/31

11:35 am-9:34 pm

1 stop15h 59m

$1,081

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Thu 5/22

7:25 pm-5:55 pm

2 stops16h 30m

Barcelona-El Prat

Fri 5/30

12:15 pm-1:23 pm

2 stops31h 08m

$1,231

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Thu 5/22

7:25 pm-5:55 pm

2 stops16h 30m

Barcelona-El Prat

Fri 5/30

3:15 pm-10:40 pm

1 stop13h 25m

$1,251

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Mon 5/19

3:00 pm-10:30 am

1 stop13h 30m

Barcelona-El Prat

Mon 5/26

8:25 pm-5:33 pm

2 stops27h 08m

$1,274

KnoxvilleMálaga

TYS - AGP

TYSAGP

Knoxville McGhee Tyson

Fri 6/13

9:55 am-7:35 am

2 stops15h 40m

Malaga

Fri 6/20

9:35 am-11:39 pm

2 stops20h 04m

$1,329

KnoxvilleMálaga

TYS - AGP

TYSAGP

Knoxville McGhee Tyson

Fri 6/13

5:45 am-1:05 pm

3 stops25h 20m

Malaga

Fri 6/20

6:10 am-11:59 pm

3 stops23h 49m

$1,369

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 18 results
1
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,086). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ES?

Find hourly flight availability from Knoxville to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

When flying from Knoxville to Spain, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated April 29, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Spain to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,244 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aer Lingus
7.0
Good
1,076 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Spain one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $637. Users have also found prices from $806 and $1,266 on Aer Lingus and British Airways, respectively.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Barcelona-El Prat. You may also consider Knoxville McGhee Tyson - Madrid Barajas or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,086). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Knoxville to Spain

Discover the top 5 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$530Average$906FlexibilityNo cancel feeOn-time75%
DeltaCheapest$530Average$1,054FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$556Average$1,304FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$562Average$1,088FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$594Average$854FlexibilityNo cancel feeOn-time70%

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