Spain

$340+ Cheap flights from Knoxville (TYS) to Spain

TYS — MAD
Nov 29 — Dec 61
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Cheap flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain

Sun 11/297:22 pm -
1 stop32h 23m
Tue 12/159:20 am -
2 stops18h 57m
Deal found 10/27$745
Sun 11/295:45 am -
2 stops21h 45m
Tue 12/156:05 am -
2 stops38h 48m
Deal found 10/27$759
Wed 11/2511:34 am -
1 stop15h 51m
Wed 12/29:00 pm -
2 stops32h 46m
Deal found 10/28$782
Thu 12/32:07 pm -
1 stop11h 38m
Tue 12/81:25 pm -
2 stops33h 35m
Deal found 10/26$799
Wed 10/285:45 am -
1 stop22h 15m
Fri 11/61:35 pm -
2 stops51h 09m
Deal found 10/28$806
Thu 12/31:38 pm -
1 stop10h 07m
Tue 12/812:40 pm -
1 stop16h 13m
Deal found 10/26$819
Thu 12/36:17 pm -
2 stops17h 28m
Tue 12/86:05 am -
2 stops21h 28m
Deal found 10/26$823
Thu 12/106:00 am -
2 stops19h 45m
Thu 12/1711:15 am -
1 stop15h 39m
Deal found 10/26$824
Sun 12/136:20 am -
1 stop20h 00m
Sun 12/201:15 pm -
2 stops31h 27m
Deal found 10/29$829
Wed 11/254:30 pm -
2 stops25h 05m
Wed 12/26:35 pm -
2 stops35h 24m
Deal found 10/28$843
Wed 11/256:05 pm -
2 stops14h 45m
Wed 12/25:20 pm -
2 stops30h 11m
Deal found 10/28$854
Wed 11/258:50 am -
1 stop14h 55m
Wed 12/212:40 pm -
1 stop14h 03m
Deal found 10/28$874

Find flight deals from Knoxville to Spain

Round-trip from

$724
(United Airlines)

One-way from

$340
(KLM)

Popular in

July

Cheapest in

January

Average price

$910
From Knoxville McGhee Tyson to Spain
One-way flight from Knoxville McGhee Tyson to Spain
Highest demand for flights based on searches. 16% potential increase in price ($174 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($35 potential savings vs. average RT price).
Average for round-trip flights in October 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleBarcelona

TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat

TYSBCN

Knoxville McGhee Tyson

Sun 4/25

12:00 pm-12:50 pm

1 stop18h 50m

Barcelona-El Prat

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$340

KnoxvilleBarcelona

TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat

TYSBCN

Knoxville McGhee Tyson

Sun 4/25

5:06 pm-10:30 pm

2 stops23h 24m

Barcelona-El Prat

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$341

KnoxvilleBarcelona

TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat

TYSBCN

Knoxville McGhee Tyson

Wed 1/27

12:20 pm-8:20 am

1 stop14h 00m

Barcelona-El Prat

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$343

KnoxvilleBarcelona

TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat

TYSBCN

Knoxville McGhee Tyson

Wed 1/27

12:02 pm-9:15 am

2 stops39h 13m

Barcelona-El Prat

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$344
Quickest round-trip

KnoxvilleBarcelona

TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat

TYSBCN

Knoxville McGhee Tyson

Sun 4/25

11:31 am-6:45 am

1 stop13h 14m

Barcelona-El Prat

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$345

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sat 12/12

4:24 pm-7:55 pm

2 stops45h 31m

Madrid Barajas

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$471

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Tue 11/17

7:52 am-9:55 am

2 stops20h 03m

Madrid Barajas

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$506

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Tue 11/17

9:45 am-8:00 am

3 stops16h 15m

Madrid Barajas

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$565

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sat 12/12

5:17 pm-5:45 am

1 stop30h 28m

Madrid Barajas

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$570

KnoxvilleBarcelona

TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat

TYSBCN

Knoxville McGhee Tyson

Tue 2/16

2:07 pm-9:00 am

1 stop12h 53m

Barcelona-El Prat

Thu 2/18

1:35 pm-7:51 pm

2 stops36h 16m

$724

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Spain (average of $483). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Spain

See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Crew

8.1

Overall

7.3

Food

6.7

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Crew

8.1

Overall

7.3

Food

6.7

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Crew

8.1

Overall

7.3

Food

6.7

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Crew

8.1

Overall

7.3

Food

6.7

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Related info for your journey

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Spain?

    Airlines like United Airlines, KLM, and Delta fly from Knoxville to Spain in about 12h 53m. The time it takes to get you to your destination can typically vary by up to 7h 23m. The distance between Knoxville and Spain is about 4465 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Spain?

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Spain (average of $483). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Knoxville to Spain

AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$432Average$950FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$591Average$829FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$640Average$1,069FlexibilityNo cancel feeOn-time71%

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