$356+ Cheap flights from Knoxville (TYS) to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Spain with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Spain
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Cheapest flights from Knoxville to SpainExplore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This Justfly.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:06 pm -
2 stops20h 44m
Fri 11/612:00 pm -
1 stop14h 49m
Deal found 9/3![British Airways logo]()
$723
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop20h 05m
Fri 11/611:00 am -
1 stop15h 17m
Deal found 9/6![American Airlines logo]()
$726
This Cheapflightsfares deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:25 pm -
2 stops21h 00m
Wed 10/148:00 am -
2 stops21h 59m
Deal found 9/2![Lufthansa logo]()
$729
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
1 stop16h 20m
Thu 10/1511:15 am -
1 stop15h 04m
Deal found 9/3![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
2 stops20h 10m
Wed 10/1411:15 am -
1 stop18h 44m
Deal found 9/4![United Airlines logo]()
$745
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:35 pm -
1 stop12h 45m
Mon 10/261:50 pm -
2 stops39h 09m
Deal found 9/3![United Airlines logo]()
$750
This United deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:55 pm -
1 stop11h 50m
Sun 11/151:25 pm -
2 stops40h 34m
Deal found 9/6![Multiple Airlines logo]()
$761
This FlightHub deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:38 pm -
2 stops34h 47m
Wed 10/1412:50 pm -
1 stop13h 28m
Deal found 9/2![British Airways logo]()
$762
This Orbitz deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:33 am -
1 stop15h 17m
Mon 11/99:40 pm -
2 stops31h 11m
Deal found 9/2![Iberia logo]()
$767
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:05 pm -
2 stops36h 45m
Fri 10/2312:45 pm -
2 stops38h 16m
Deal found 9/3![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:45 am -
1 stop20h 35m
Sun 10/256:50 am -
2 stops22h 09m
Deal found 9/3![United Airlines logo]()
$779
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:45 am -
1 stop20h 20m
Sun 10/256:05 am -
2 stops22h 54m
Deal found 9/3![United Airlines logo]()
$781
Best flights from Knoxville to SpainDiscover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Justfly.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:33 am -
2 stops23h 02m
Wed 11/1812:00 pm -
1 stop14h 49m
Deal found 9/5![British Airways logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
1 stop16h 20m
Thu 10/156:05 am -
2 stops20h 40m
Deal found 9/3![United Airlines logo]()
$731
This Orbitz deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:33 am -
1 stop15h 17m
Mon 11/99:40 pm -
2 stops31h 11m
Deal found 9/2![Iberia logo]()
$767
This Ovago deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
2 stops27h 50m
Mon 10/266:30 am -
2 stops22h 29m
Deal found 9/4![SWISS logo]()
$862
This KLM deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:17 pm -
2 stops19h 13m
Tue 12/2910:40 am -
2 stops28h 51m
Deal found 9/2![KLM logo]()
$924
This KAYAK deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:05 pm -
2 stops17h 15m
Wed 12/301:40 pm -
2 stops40h 35m
Deal found 9/3![Multiple Airlines logo]()
$1,060
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/155:40 am -
2 stops27h 35m
Fri 1/11:00 pm -
2 stops39h 09m
Deal found 9/6![Delta logo]()
$1,264
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
2 stops17h 50m
Wed 10/1411:15 am -
1 stop18h 44m
Deal found 9/6![United Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
2 stops20h 00m
Mon 10/261:50 pm -
2 stops39h 09m
Deal found 9/3![United Airlines logo]()
$753
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/112:20 pm -
1 stop14h 00m
Fri 2/51:35 pm -
3 stops36h 16m
Deal found 9/6![United Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1712:20 pm -
1 stop14h 55m
Thu 1/216:05 am -
2 stops19h 12m
Deal found 9/6![United Airlines logo]()
$759
This FlightHub deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/164:59 pm -
2 stops36h 31m
Wed 12/307:15 pm -
2 stops31h 42m
Deal found 9/2![British Airways logo]()
$1,124
This KAYAK deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:05 pm -
2 stops17h 15m
Thu 12/3111:55 am -
2 stops18h 20m
Deal found 9/3![Multiple Airlines logo]()
$1,133
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:45 am -
1 stop20h 20m
Sun 10/256:05 am -
2 stops22h 54m
Deal found 9/5![United Airlines logo]()
$781
This British Airways deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:42 pm -
2 stops22h 08m
Fri 11/209:10 am -
2 stops20h 37m
Deal found 9/4![British Airways logo]()
$1,300
Last-minute flights from Knoxville to SpainDiscover last-minute flight deals from Knoxville to Spain. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Spain. Data last updated September 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:42 am -
2 stops38h 08m
Thu 10/2210:50 am -
1 stop15h 55m
Deal found 9/3![United Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:05 pm -
2 stops36h 45m
Fri 10/2312:45 pm -
2 stops38h 16m
Deal found 9/3![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:35 pm -
1 stop12h 45m
Mon 10/261:50 pm -
2 stops39h 09m
Deal found 9/3![United Airlines logo]()
$750
This Cheapflightsfares deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:25 pm -
2 stops21h 00m
Wed 10/148:00 am -
2 stops21h 59m
Deal found 9/2![Lufthansa logo]()
$729
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
1 stop16h 20m
Thu 10/156:05 am -
2 stops20h 40m
Deal found 9/3![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
2 stops20h 10m
Wed 10/1411:15 am -
1 stop18h 44m
Deal found 9/4![United Airlines logo]()
$745
This FlightHub deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:38 pm -
2 stops34h 47m
Wed 10/1412:50 pm -
1 stop13h 28m
Deal found 9/2![British Airways logo]()
$762
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:45 am -
1 stop20h 20m
Sun 10/256:05 am -
2 stops22h 54m
Deal found 9/3![United Airlines logo]()
$781
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:45 am -
1 stop20h 35m
Sun 10/256:50 am -
2 stops22h 09m
Deal found 9/3![United Airlines logo]()
$779
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:45 am -
1 stop16h 20m
Thu 10/296:25 am -
2 stops18h 11m
Deal found 9/7![United Airlines logo]()
$782
This Justfly.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:06 pm -
2 stops20h 44m
Fri 11/612:00 pm -
1 stop14h 49m
Deal found 9/3![British Airways logo]()
$723
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop20h 05m
Fri 11/611:00 am -
1 stop15h 17m
Deal found 9/6![American Airlines logo]()
$726
One-way flights from Knoxville to SpainSearch for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:40 pm -
2 stops33h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![United Airlines logo]()
$356
This British Airways deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:12 pm -
1 stop31h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![British Airways logo]()
$361
This FlightHub deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:55 pm -
2 stops16h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![British Airways logo]()
$498
This Air Canada deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:45 am -
3 stops16h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Air Canada logo]()
$565
This Air Canada deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:45 am -
3 stops17h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Air Canada logo]()
$1,111
This Thrive Travel deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:42 pm -
2 stops17h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$2,742
This Thrive Travel deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:42 pm -
1 stop38h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![British Airways logo]()
$3,120
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:45 am -
3 stops17h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Air Canada logo]()
$6,733
Find flight deals from Knoxville to Spain
Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated September 7, 2026.
Round-trip from | $723 (FlightHub) |
|---|---|
One-way from | $356 (United Airlines) |
Popular in | July |
Cheapest in | January |
Average price | $1,022 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
5:40 pm-9:15 am
2 stops33h 35m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$356
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
4:12 pm-5:45 am
1 stop31h 33m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$361
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Fri 10/30
6:55 pm-4:35 pm
2 stops16h 40m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$498
Quickest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
9:45 am-8:00 am
3 stops16h 15m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$565
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Wed 11/11
11:33 am-4:35 pm
2 stops23h 02m
Barcelona-El Prat
Wed 11/18
12:00 pm-8:49 pm
1 stop14h 49m
$723
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Wed 10/7
9:45 am-8:05 am
1 stop16h 20m
Madrid Barajas
Thu 10/15
6:05 am-8:45 pm
2 stops20h 40m
$731
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Wed 10/7
9:45 am-9:35 am
2 stops17h 50m
Barcelona-El Prat
Wed 10/14
11:15 am-11:59 pm
1 stop18h 44m
$746
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Mon 10/5
6:00 am-8:00 am
2 stops20h 00m
Barcelona-El Prat
Mon 10/26
1:50 pm-11:59 pm
2 stops39h 09m
$753
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Mon 2/1
12:20 pm-8:20 am
1 stop14h 00m
Barcelona-El Prat
Fri 2/5
1:35 pm-7:51 pm
3 stops36h 16m
$754
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 1/17
12:20 pm-9:15 am
1 stop14h 55m
Madrid Barajas
Thu 1/21
6:05 am-7:17 pm
2 stops19h 12m
$759
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Spain
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What is the cheapest month to book a flight from Knoxville to Spain?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Spain (average of $483). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated September 7, 2026.
See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Spain by cabin class
Find flights from Knoxville to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Spain flights
Browse other Knoxville and Spain flight options. Last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Spain flights
Consider these flights traveling from Knoxville to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 3 airlines flying from Knoxville to Spain
Discover the top 3 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$432 | Average$933 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$591 | Average$843 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$640 | Average$1,069 | FlexibilityNo cancel fee | On-time71% |