$277+ Cheap flights from Knoxville (TYS) to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Sep 24 — Oct 11
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Spain with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to SpainExplore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 25, 2026.
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 25, 2026.
This Expedia deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:31 am -
1 stop16h 04m
Thu 11/121:00 pm -
1 stop16h 47m
Deal found 8/24![Iberia logo]()
$709
This Expedia deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:33 am -
1 stop15h 17m
Tue 12/156:05 pm -
2 stops35h 42m
Deal found 8/20![Iberia logo]()
$721
This Expedia deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:35 pm -
2 stops22h 00m
Thu 11/1212:00 pm -
2 stops38h 54m
Deal found 8/24![Lufthansa logo]()
$724
This Priceline deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:55 pm -
2 stops16h 35m
Wed 10/211:35 pm -
1 stop16h 24m
Deal found 8/24![Iberia logo]()
$728
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:30 pm -
1 stop10h 45m
Thu 11/126:05 am -
2 stops20h 49m
Deal found 8/24![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:45 am -
2 stops20h 30m
Thu 11/1211:00 am -
1 stop14h 36m
Deal found 8/24![United Airlines logo]()
$735
This KLM deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:29 am -
2 stops13h 51m
Wed 10/216:00 am -
2 stops15h 26m
Deal found 8/24![KLM logo]()
$737
This Air Canada deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:45 am -
2 stops19h 15m
Tue 11/101:25 pm -
2 stops16h 34m
Deal found 8/24![Air Canada logo]()
$738
This Air Canada deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:45 am -
2 stops19h 15m
Thu 11/121:25 pm -
2 stops53h 48m
Deal found 8/24![Air Canada logo]()
$743
This Finnair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:31 am -
1 stop15h 19m
Mon 11/169:40 pm -
2 stops30h 04m
Deal found 8/22![Multiple Airlines logo]()
$745
This Air Canada deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:16 am -
3 stops15h 44m
Tue 12/151:25 pm -
2 stops26h 35m
Deal found 8/20![Multiple Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop25h 15m
Fri 10/1612:15 pm -
2 stops51h 38m
Deal found 8/22![United Airlines logo]()
$795
Best flights from Knoxville to SpainDiscover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 25, 2026.
Discover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 25, 2026.
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:45 am -
2 stops20h 30m
Fri 11/1311:15 am -
2 stops18h 44m
Deal found 8/24![United Airlines logo]()
$735
This KLM deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:29 am -
2 stops13h 51m
Wed 10/216:00 am -
2 stops15h 26m
Deal found 8/24![KLM logo]()
$737
This Gurufare deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:15 pm -
2 stops16h 55m
Fri 10/98:05 pm -
2 stops26h 13m
Deal found 8/21![British Airways logo]()
$1,085
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:43 am -
2 stops15h 02m
Thu 11/1211:15 am -
2 stops28h 38m
Deal found 8/24![United Airlines logo]()
$735
This Expedia deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 pm -
2 stops18h 50m
Mon 10/1211:40 pm -
2 stops24h 44m
Deal found 8/21![KLM logo]()
$801
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:30 am -
1 stop17h 50m
Fri 2/51:35 pm -
2 stops33h 14m
Deal found 8/22![United Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/174:16 pm -
1 stop10h 59m
Thu 1/216:05 am -
2 stops19h 12m
Deal found 8/22![United Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:30 pm -
1 stop10h 45m
Tue 11/1011:00 am -
1 stop18h 59m
Deal found 8/24![United Airlines logo]()
$761
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:20 am -
2 stops23h 25m
Tue 12/226:05 am -
2 stops24h 10m
Deal found 8/23![United Airlines logo]()
$769
This British Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:20 am -
2 stops19h 10m
Fri 10/98:05 pm -
2 stops44h 28m
Deal found 8/21![British Airways logo]()
$1,134
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/162:20 pm -
1 stop12h 40m
Thu 2/1811:00 am -
1 stop15h 54m
Deal found 8/24![United Airlines logo]()
$774
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:16 pm -
1 stop10h 44m
Sun 10/258:35 am -
2 stops20h 24m
Deal found 8/23![United Airlines logo]()
$781
This British Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:42 pm -
2 stops22h 08m
Fri 11/209:10 am -
2 stops20h 32m
Deal found 8/21![British Airways logo]()
$1,299
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop25h 15m
Fri 10/1612:15 pm -
2 stops51h 38m
Deal found 8/22![United Airlines logo]()
$795
This Air Canada deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:45 am -
3 stops20h 40m
Fri 10/910:25 am -
3 stops19h 34m
Deal found 8/21![Air Canada logo]()
$3,393
Last-minute flights from Knoxville to SpainDiscover last-minute flight deals from Knoxville to Spain. Data last updated August 25, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Spain. Data last updated August 25, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:20 pm -
2 stops21h 05m
Fri 9/118:00 am -
2 stops21h 59m
Deal found 8/21![Lufthansa logo]()
$998
This KLM deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:12 pm -
2 stops14h 38m
Fri 9/1111:00 am -
1 stop15h 07m
Deal found 8/24![Multiple Airlines logo]()
$1,013
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:25 pm -
2 stops16h 00m
Fri 9/1111:00 am -
1 stop17h 27m
Deal found 8/21![Delta logo]()
$1,017
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:20 pm -
1 stop30h 45m
Sun 10/118:15 am -
2 stops32h 22m
Deal found 8/22![United Airlines logo]()
$873
This British Airways deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:30 am -
1 stop17h 05m
Sun 10/113:20 pm -
1 stop32h 15m
Deal found 8/22![British Airways logo]()
$925
This Air Canada deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:45 am -
3 stops17h 05m
Sun 10/1112:45 pm -
2 stops27h 00m
Deal found 8/22![Multiple Airlines logo]()
$1,393
This Air Canada deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:45 am -
3 stops17h 05m
Sun 10/1112:45 pm -
3 stops17h 14m
Deal found 8/22![Air Canada logo]()
$2,180
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:06 pm -
2 stops14h 09m
Fri 10/212:20 pm -
1 stop16h 47m
Deal found 8/20![American Airlines logo]()
$800
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops20h 40m
Fri 10/23:15 pm -
2 stops25h 22m
Deal found 8/23![United Airlines logo]()
$808
This FlightHub deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:15 pm -
2 stops16h 20m
Fri 10/27:40 am -
2 stops18h 03m
Deal found 8/21![British Airways logo]()
$818
One-way flights from Knoxville to SpainSearch for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated August 25, 2026.
Search for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated August 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:49 pm -
2 stops23h 06m
Deal found 8/23![Multiple Airlines logo]()
$277
This Expedia deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:00 am -
1 stop20h 55m
Deal found 8/23![British Airways logo]()
$340
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:45 am -
2 stops21h 30m
Deal found 8/23![United Airlines logo]()
$350
This British Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:12 pm -
1 stop31h 33m
Deal found 8/24![British Airways logo]()
$361
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:35 pm -
2 stops31h 40m
Deal found 8/24![United Airlines logo]()
$367
This FlightHub deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:35 am -
1 stop15h 30m
Deal found 8/23![British Airways logo]()
$458
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:30 am -
1 stop21h 10m
Deal found 8/20![Multiple Airlines logo]()
$472
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:34 am -
2 stops36h 46m
Deal found 8/20![Multiple Airlines logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am -
3 stops34h 45m
Deal found 8/24![Multiple Airlines logo]()
$500
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:45 am -
1 stop16h 20m
Deal found 8/20![United Airlines logo]()
$513
This Air Canada deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:45 am -
3 stops16h 15m
Deal found 8/21![Air Canada logo]()
$522
This Cheapflightsfares deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:22 pm -
2 stops27h 08m
Deal found 8/24![Aer Lingus logo]()
$564
Find flight deals from Knoxville to Spain
Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated August 25, 2026.
Round-trip from | $709 (Expedia) |
|---|---|
One-way from | $277 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $887 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 25, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 11/1
6:45 am-9:15 am
2 stops20h 30m
Madrid Barajas
Fri 11/13
11:15 am-11:59 pm
2 stops18h 44m
$735
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Mon 11/2
10:43 am-7:45 am
2 stops15h 02m
Madrid Barajas
Thu 11/12
11:15 am-9:53 am
2 stops28h 38m
$735
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Tue 10/6
10:29 am-6:20 am
2 stops13h 51m
Madrid Barajas
Wed 10/21
6:00 am-3:26 pm
2 stops15h 26m
$737
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Mon 2/1
8:30 am-8:20 am
1 stop17h 50m
Barcelona-El Prat
Fri 2/5
1:35 pm-4:49 pm
2 stops33h 14m
$754
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 1/17
4:16 pm-9:15 am
1 stop10h 59m
Madrid Barajas
Thu 1/21
6:05 am-7:17 pm
2 stops19h 12m
$759
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Wed 11/4
4:30 pm-9:15 am
1 stop10h 45m
Madrid Barajas
Tue 11/10
11:00 am-11:59 pm
1 stop18h 59m
$761
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Tue 12/15
6:20 am-11:45 am
2 stops23h 25m
Madrid Barajas
Tue 12/22
6:05 am-12:15 am
2 stops24h 10m
$769
Quickest round-trip
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Tue 2/16
2:20 pm-9:00 am
1 stop12h 40m
Barcelona-El Prat
Thu 2/18
11:00 am-8:54 pm
1 stop15h 54m
$774
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Wed 10/14
4:16 pm-9:00 am
1 stop10h 44m
Madrid Barajas
Sun 10/25
8:35 am-11:59 pm
2 stops20h 24m
$781
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Mon 10/5
6:00 am-1:15 pm
1 stop25h 15m
Barcelona-El Prat
Fri 10/16
12:15 pm-9:53 am
2 stops51h 38m
$795
Showing 1-10 of 27 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Spain
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What is the cheapest month to book a flight from Knoxville to Spain?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Spain (average of $483). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated August 25, 2026.
See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Comfort
7.3
Overall
7.4
Crew
8.1
Boarding
7.7
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Overall
7.4
Crew
8.1
Boarding
7.7
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Overall
7.4
Crew
8.1
Boarding
7.7
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Overall
7.4
Crew
8.1
Boarding
7.7
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Spain by cabin class
Find flights from Knoxville to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Spain flights
Browse other Knoxville and Spain flight options. Last updated on August 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Spain flights
Consider these flights traveling from Knoxville to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 3 airlines flying from Knoxville to Spain
Discover the top 3 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$432 | Average$933 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$591 | Average$843 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$640 | Average$1,059 | FlexibilityNo cancel fee | On-time71% |