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$354+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Aug 10 — Aug 171
Mon 8/10
Mon 8/17
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.

This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:00 pm
TYS
-
MAD
1 stop11h 45m
United Airlines
Thu 11/121:25 pm
MAD
-
TYS
2 stops37h 19m
United Airlines
Deal found 7/6$733
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:45 am
TYS
-
BCN
1 stop21h 15m
United Airlines
Fri 11/131:35 pm
BCN
-
TYS
2 stops31h 08m
United Airlines
Deal found 7/9$749
This British Airways deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:06 pm
TYS
-
MAD
2 stops14h 49m
British Airways
Wed 10/281:00 pm
MAD
-
TYS
1 stop15h 55m
British Airways
Deal found 7/8$750
This Air Canada deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:45 am
TYS
-
BCN
2 stops17h 50m
Air Canada
Fri 11/131:35 pm
BCN
-
TYS
2 stops31h 08m
Air Canada
Deal found 7/9$752
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:15 am
TYS
-
MAD
2 stops19h 45m
United Airlines
Wed 10/2811:00 am
MAD
-
TYS
2 stops27h 50m
United Airlines
Deal found 7/8$758
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:51 pm
TYS
-
BCN
2 stops14h 54m
American Airlines
Tue 11/1011:00 am
BCN
-
TYS
1 stop18h 45m
American Airlines
Deal found 7/9$765
This British Airways deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:57 pm
TYS
-
BCN
2 stops15h 18m
British Airways
Wed 10/2812:00 pm
BCN
-
TYS
1 stop13h 18m
British Airways
Deal found 7/7$766
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:59 pm
TYS
-
BCN
2 stops24h 56m
United Airlines
Fri 11/61:35 pm
BCN
-
TYS
2 stops37h 09m
United Airlines
Deal found 7/10$767
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:57 pm
TYS
-
BCN
1 stop11h 38m
American Airlines
Fri 11/612:00 pm
BCN
-
TYS
1 stop15h 04m
American Airlines
Deal found 7/8$769
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:51 pm
TYS
-
BCN
2 stops14h 49m
American Airlines
Thu 11/1911:50 am
BCN
-
TYS
2 stops15h 41m
American Airlines
Deal found 7/10$770
This Orbitz deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:45 am
TYS
-
MAD
2 stops43h 05m
Multiple Airlines
Sat 10/245:55 am
MAD
-
TYS
2 stops24h 04m
Multiple Airlines
Deal found 7/9$771
This FlightHub deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:57 pm
TYS
-
BCN
1 stop11h 38m
British Airways
Fri 11/612:00 pm
BCN
-
TYS
1 stop15h 04m
British Airways
Deal found 7/9$776

Find flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated July 11, 2026.

Round-trip from

$733
(United Airlines)

One-way from

$354
(oojo)

Popular in

July

Cheapest in

January

Average price

$1,244
From Knoxville McGhee Tyson to Spain
Search Deals
One-way flight from Knoxville McGhee Tyson to Spain
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($182 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 11/8

2:00 pm-7:45 am

1 stop11h 45m

Madrid Barajas

Thu 11/12

1:25 pm-8:44 pm

2 stops37h 19m

$733

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 11/11

10:48 am-1:15 pm

1 stop20h 27m

Barcelona-El Prat

Fri 11/13

1:35 pm-11:56 pm

2 stops40h 21m

$749

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 11/11

5:45 am-9:00 am

1 stop21h 15m

Barcelona-El Prat

Fri 11/13

1:35 pm-2:43 pm

2 stops31h 08m

$749

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 10/14

6:06 pm-2:55 pm

2 stops14h 49m

Madrid Barajas

Wed 10/28

1:00 pm-11:55 pm

1 stop15h 55m

$750

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 11/4

7:00 am-9:35 am

2 stops20h 35m

Barcelona-El Prat

Thu 11/19

10:30 am-11:56 pm

1 stop19h 26m

$772

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Tue 11/3

10:48 am-9:00 am

2 stops16h 12m

Barcelona-El Prat

Tue 11/10

11:00 am-11:56 pm

2 stops18h 56m

$773

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 10/28

6:57 pm-4:30 pm

2 stops16h 33m

Barcelona-El Prat

Fri 11/6

10:50 am-11:59 pm

1 stop19h 09m

$777

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 1/4

7:30 am-8:50 am

1 stop19h 20m

Madrid Barajas

Thu 1/14

10:00 am-11:59 pm

1 stop19h 59m

$783

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 10/10

7:25 pm-8:05 am

1 stop30h 40m

Madrid Barajas

Sat 10/24

5:55 am-8:19 pm

2 stops20h 24m

$785

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 9/23

1:10 pm-8:20 am

1 stop13h 10m

Barcelona-El Prat

Fri 10/2

11:15 am-11:59 pm

1 stop18h 44m

$803

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/11

Showing 1-10 of 25 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Spain (average of $432). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated July 11, 2026.
See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,980 reviews

Boarding

7.7

Food

6.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
United Airlines
7.4
Good
9,980 reviews
United Airlines
7.4
Good
9,980 reviews

Boarding

7.7

Food

6.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
American Airlines
7.1
Good
11,806 reviews
United Airlines
7.4
Good
9,980 reviews

Boarding

7.7

Food

6.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
British Airways
6.7
Okay
8,107 reviews
United Airlines
7.4
Good
9,980 reviews

Boarding

7.7

Food

6.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Spain?

    Airlines like United Airlines, British Airways, and Delta fly from Knoxville to Spain in about 11h 45m. The time it takes to get you to your destination can typically vary by up to 4h 48m. The distance between Knoxville and Spain is about 4222 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Barcelona-El Prat. You may also consider Knoxville McGhee Tyson - Madrid Barajas or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Spain (average of $432). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to Spain

Discover the top 3 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$432Average$795FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$605Average$873FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$664Average$864FlexibilityNo cancel feeOn-time69%

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