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$265+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated junio 12, 2025.

Round-trip from

$559
(United Airlines)

One-way from

$265
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$1,579
From Knoxville McGhee Tyson to Spain
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One-way flight from Knoxville McGhee Tyson to Spain
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Highest demand for flights based on searches. 23% potential increase in price ($316 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($48 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/410:35 amTYS - BCN
1 stop20h 30mUnited Airlines
jue. 11/131:35 pmBCN - TYS
2 stops38h 46mUnited Airlines
Deal found 6/12$559
This Gotogate deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:26 pmTYS - BCN
2 stops32h 09mMultiple Airlines
mié. 11/56:20 pmBCN - TYS
2 stops35h 39mMultiple Airlines
Deal found 6/12$572
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/115:45 amTYS - MAD
2 stops20h 20mUnited Airlines
mié. 11/191:20 pmMAD - TYS
2 stops16h 39mUnited Airlines
Deal found 6/10$586
This Finnair deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/911:09 amTYS - MAD
1 stop12h 36mMultiple Airlines
mié. 11/191:15 pmMAD - TYS
1 stop13h 21mMultiple Airlines
Deal found 6/9$587
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/55:30 amTYS - MAD
2 stops20h 30mDelta
vie. 11/1410:00 amMAD - TYS
2 stops17h 32mDelta
Deal found 6/10$591
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/44:10 pmTYS - BCN
2 stops15h 30mAmerican Airlines
jue. 11/1310:35 amBCN - TYS
2 stops16h 01mAmerican Airlines
Deal found 6/11$602
This Lufthansa deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/57:20 pmTYS - MAD
2 stops16h 30mLufthansa
mar. 11/186:05 amMAD - TYS
2 stops20h 15mLufthansa
Deal found 6/11$614
This British Airways deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/1410:55 amTYS - BCN
1 stop16h 10mBritish Airways
mar. 9/162:00 pmBCN - TYS
1 stop13h 14mBritish Airways
Deal found 6/9$632
This Kissandfly.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/35:45 amTYS - BCN
2 stops25h 30mLufthansa
mar. 8/1911:15 amBCN - TYS
2 stops28h 58mLufthansa
Deal found 6/12$640
This Air Canada deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/149:55 amTYS - BCN
3 stops15h 55mAir Canada
mar. 9/1610:20 amBCN - TYS
3 stops19h 37mAir Canada
Deal found 6/10$647
This Expedia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:54 pmTYS - MAD
2 stops35h 16mBritish Airways
dom. 11/167:40 amMAD - TYS
2 stops18h 56mBritish Airways
Deal found 6/11$666
This KLM deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/87:07 amTYS - MAD
1 stop19h 53mKLM
sáb. 11/1511:00 amMAD - TYS
1 stop13h 13mKLM
Deal found 6/10$686

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

mar. 11/4

10:35 am-1:05 pm

1 stop20h 30m

Barcelona-El Prat

jue. 11/13

1:35 pm-10:21 pm

2 stops38h 46m

$559

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

sáb. 10/25

7:26 pm-9:35 am

2 stops32h 09m

Barcelona-El Prat

mié. 11/5

6:20 pm-11:59 pm

2 stops35h 39m

$572

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

mar. 11/11

5:45 am-8:05 am

2 stops20h 20m

Madrid Barajas

mié. 11/19

1:20 pm-11:59 pm

2 stops16h 39m

$586

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

dom. 11/9

11:09 am-5:45 am

1 stop12h 36m

Madrid Barajas

mié. 11/19

1:15 pm-8:36 pm

1 stop13h 21m

$587

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

mié. 11/5

5:30 am-8:00 am

2 stops20h 30m

Madrid Barajas

jue. 11/13

11:00 am-11:46 pm

1 stop18h 46m

$591

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

mar. 11/4

4:10 pm-1:40 pm

2 stops15h 30m

Barcelona-El Prat

jue. 11/13

10:35 am-8:36 pm

2 stops16h 01m

$602

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

mié. 11/5

7:20 pm-5:50 pm

2 stops16h 30m

Madrid Barajas

mar. 11/18

6:05 am-8:20 pm

2 stops20h 15m

$614

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

jue. 8/14

10:55 am-9:05 am

1 stop16h 10m

Barcelona-El Prat

mar. 9/16

2:00 pm-9:14 pm

1 stop13h 14m

$632

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

dom. 8/3

5:45 am-1:15 pm

2 stops25h 30m

Barcelona-El Prat

mar. 8/19

11:15 am-10:13 am

2 stops28h 58m

$640

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

jue. 8/14

9:55 am-7:50 am

3 stops15h 55m

Barcelona-El Prat

mar. 9/16

10:20 am-11:57 pm

3 stops19h 37m

$647

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 29 results
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,057). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ES?

Find hourly flight availability from Knoxville to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Knoxville to Spain, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated junio 12, 2025.
Peruse reviews from past customers who have flown with Delta, KLM and Brussels Airlines from Knoxville to Spain to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,358 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Brussels Airlines
7.4
Good
355 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Virgin Atlantic
7.4
Good
652 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Spain one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $468. Users have also found prices from $475 and $481 on Air Canada and United Airlines, respectively.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Madrid Barajas. You may also consider Knoxville McGhee Tyson - Barcelona-El Prat or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Spain (average of $543). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,057). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Knoxville to Spain

Discover the top 5 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$530Average$828FlexibilityNo cancel feeOn-time75%
DeltaCheapest$530Average$1,054FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$562Average$974FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$594Average$880FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$690Average$1,279FlexibilityNo cancel feeOn-time71%

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