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$341+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Jun 14 — Jun 211
Sun 6/14
Sun 6/21
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.

This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:35 pm
TYS
-
MAD
1 stop30h 10m
United Airlines
Tue 11/101:35 pm
MAD
-
TYS
2 stops40h 02m
United Airlines
Deal found 5/13$740
This oojo deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:21 am
TYS
-
MAD
1 stop17h 09m
British Airways
Fri 11/61:15 pm
MAD
-
TYS
1 stop13h 49m
British Airways
Deal found 5/10$749
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:30 am
TYS
-
BCN
1 stop23h 10m
Multiple Airlines
Wed 7/86:30 pm
BCN
-
TYS
1 stop24h 32m
Multiple Airlines
Deal found 5/14$751
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:35 pm
TYS
-
MAD
1 stop12h 30m
United Airlines
Wed 10/215:55 am
MAD
-
TYS
2 stops24h 00m
United Airlines
Deal found 5/13$755
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:45 am
TYS
-
MAD
1 stop20h 20m
United Airlines
Fri 11/66:25 am
MAD
-
TYS
2 stops16h 24m
United Airlines
Deal found 5/10$756
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:02 pm
TYS
-
BCN
1 stop13h 13m
United Airlines
Fri 10/211:15 am
BCN
-
TYS
1 stop18h 40m
United Airlines
Deal found 5/15$769
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:20 pm
TYS
-
BCN
1 stop13h 40m
United Airlines
Fri 11/63:05 pm
BCN
-
TYS
1 stop15h 09m
United Airlines
Deal found 5/13$770
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:42 am
TYS
-
MAD
2 stops38h 08m
United Airlines
Fri 10/1612:45 pm
MAD
-
TYS
2 stops35h 20m
United Airlines
Deal found 5/15$772
This KLM deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:20 pm
TYS
-
BCN
2 stops13h 40m
Multiple Airlines
Fri 11/610:50 am
BCN
-
TYS
1 stop18h 56m
Multiple Airlines
Deal found 5/13$774
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:59 pm
TYS
-
MAD
2 stops16h 36m
British Airways
Mon 11/98:50 pm
MAD
-
TYS
2 stops30h 34m
British Airways
Deal found 5/14$791
This Ovago deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:04 pm
TYS
-
MAD
1 stop27h 41m
British Airways
Tue 11/1012:35 pm
MAD
-
TYS
1 stop17h 10m
British Airways
Deal found 5/13$798
This British Airways deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:30 pm
TYS
-
BCN
2 stops15h 25m
British Airways
Fri 10/210:15 am
BCN
-
TYS
2 stops17h 00m
British Airways
Deal found 5/15$801

Find flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated May 15, 2026.

Round-trip from

$740
(United Airlines)

One-way from

$341
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$1,341
From Knoxville McGhee Tyson to Spain
Search Deals
One-way flight from Knoxville McGhee Tyson to Spain
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($369 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($50 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 11/7

7:35 pm-11:45 am

2 stops34h 10m

Madrid Barajas

Tue 11/10

1:35 pm-7:17 pm

2 stops35h 42m

$748

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 9/23

5:45 am-8:05 am

1 stop20h 20m

Madrid Barajas

Fri 11/6

6:25 am-4:49 pm

2 stops16h 24m

$756

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 10/28

10:16 am-9:00 am

1 stop17h 44m

Barcelona-El Prat

Fri 11/6

10:30 am-7:17 pm

1 stop14h 47m

$769

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 10/10

10:42 am-6:50 am

2 stops38h 08m

Madrid Barajas

Fri 10/16

12:45 pm-6:05 pm

2 stops35h 20m

$772

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 9/23

5:45 am-8:00 am

2 stops20h 15m

Barcelona-El Prat

Fri 10/2

3:15 pm-12:30 am

1 stop15h 15m

$773
Quickest round-trip

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 9/23

6:30 pm-3:55 pm

2 stops15h 25m

Barcelona-El Prat

Fri 10/2

10:15 am-9:15 pm

2 stops17h 00m

$801

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 10/2

7:20 pm-8:05 am

1 stop30h 45m

Madrid Barajas

Mon 10/12

12:45 pm-11:55 pm

2 stops41h 10m

$840

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 9/8

5:45 am-8:05 am

1 stop20h 20m

Madrid Barajas

Fri 9/25

6:00 am-11:55 pm

2 stops23h 55m

$841
Cheapest one-way

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 10/28

9:10 am-1:40 pm

2 stops23h 30m

$341

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Fri 11/6

7:10 am-1:40 pm

2 stops24h 30m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/12

Showing 1-10 of 23 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Spain (average of $432). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,415). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated May 15, 2026.
See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,724 reviews

Boarding

7.7

Food

6.6

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,724 reviews
United Airlines
7.4
Good
9,724 reviews

Boarding

7.7

Food

6.6

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
American Airlines
7.1
Good
11,665 reviews
United Airlines
7.4
Good
9,724 reviews

Boarding

7.7

Food

6.6

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
British Airways
6.7
Okay
7,981 reviews
United Airlines
7.4
Good
9,724 reviews

Boarding

7.7

Food

6.6

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Spain?

    Airlines like United Airlines fly from Knoxville to Spain in about 34h 10m. The time it takes to get you to your destination can typically vary by up to . The distance between Knoxville and Spain is about 4222 mi.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Madrid Barajas. You may also consider Knoxville McGhee Tyson - Barcelona-El Prat or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Spain (average of $432). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,415). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to Spain

Discover the top 3 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$432Average$835FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$512Average$896FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$587Average$773FlexibilityNo cancel feeOn-time69%

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