$351+ Cheap flights from Knoxville (TYS) to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to SpainExplore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:26 am -
2 stops18h 54m
Fri 11/139:20 am -
2 stops20h 39m
Deal found 9/18![Delta logo]()
$584
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:40 am -
1 stop22h 05m
Tue 11/2412:20 pm -
1 stop15h 52m
Deal found 9/18![Delta logo]()
$585
This Air France deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:34 pm -
1 stop14h 06m
Wed 11/186:00 am -
2 stops17h 22m
Deal found 9/20![Air France logo]()
$602
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:26 am -
2 stops18h 54m
Wed 11/116:00 am -
2 stops22h 12m
Deal found 9/17![Delta logo]()
$608
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:00 am -
2 stops15h 35m
Wed 10/711:10 am -
2 stops28h 24m
Deal found 9/20![Delta logo]()
$612
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:40 am -
1 stop25h 10m
Wed 10/711:10 am -
2 stops28h 24m
Deal found 9/20![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:40 pm -
2 stops17h 20m
Wed 11/186:00 am -
2 stops23h 11m
Deal found 9/20![Delta logo]()
$620
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:40 am -
1 stop21h 00m
Sun 11/2210:50 am -
1 stop15h 19m
Deal found 9/16![Delta logo]()
$625
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:23 pm -
2 stops17h 07m
Fri 11/66:00 am -
2 stops19h 49m
Deal found 9/21![Delta logo]()
$632
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:35 am -
1 stop20h 10m
Fri 11/139:20 am -
2 stops15h 07m
Deal found 9/17![Delta logo]()
$634
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:23 pm -
1 stop10h 22m
Wed 11/1110:50 am -
2 stops16h 39m
Deal found 9/17![Delta logo]()
$653
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:55 pm -
1 stop11h 50m
Sun 11/151:25 pm -
2 stops37h 29m
Deal found 9/20![United Airlines logo]()
$690
Best flights from Knoxville to SpainDiscover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Knoxville to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:22 pm -
2 stops16h 23m
Tue 11/2412:20 pm -
1 stop15h 52m
Deal found 9/18![Delta logo]()
$599
This KLM deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/510:05 am -
2 stops15h 15m
Fri 2/129:20 am -
2 stops18h 25m
Deal found 9/18![KLM logo]()
$639
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:55 pm -
1 stop11h 50m
Sun 11/151:25 pm -
2 stops37h 29m
Deal found 9/20![United Airlines logo]()
$690
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:40 pm -
2 stops17h 20m
Wed 11/186:00 am -
2 stops23h 11m
Deal found 9/20![Delta logo]()
$620
This British Airways deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:42 pm -
2 stops22h 08m
Fri 11/209:10 am -
2 stops20h 37m
Deal found 9/20![British Airways logo]()
$1,320
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:23 pm -
2 stops17h 07m
Fri 11/66:00 am -
2 stops19h 49m
Deal found 9/20![Delta logo]()
$632
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:45 am -
1 stop17h 15m
Wed 11/1810:30 am -
1 stop19h 29m
Deal found 9/20![United Airlines logo]()
$706
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/58:47 am -
1 stop20h 58m
Fri 2/129:20 am -
2 stops29h 52m
Deal found 9/20![Delta logo]()
$639
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1312:45 pm -
1 stop14h 45m
Wed 1/1311:15 am -
1 stop14h 36m
Deal found 9/19![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:25 pm -
1 stop30h 40m
Sun 10/256:05 am -
2 stops22h 54m
Deal found 9/19![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:45 am -
1 stop20h 20m
Wed 10/218:25 am -
2 stops21h 34m
Deal found 9/16![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:35 pm -
1 stop31h 10m
Mon 11/96:25 am -
2 stops35h 05m
Deal found 9/17![United Airlines logo]()
$712
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:25 pm -
2 stops16h 30m
Wed 10/146:40 am -
2 stops19h 39m
Deal found 9/20![United Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:45 am -
2 stops20h 25m
Fri 11/610:30 am -
1 stop31h 00m
Deal found 9/18![United Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 am -
2 stops21h 50m
Wed 10/76:00 am -
2 stops20h 49m
Deal found 9/20![United Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:42 am -
2 stops21h 43m
Wed 10/711:15 am -
1 stop29h 22m
Deal found 9/20![United Airlines logo]()
$809
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:42 am -
2 stops21h 43m
Wed 10/76:00 am -
2 stops20h 49m
Deal found 9/20![United Airlines logo]()
$811
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:45 am -
2 stops30h 10m
Fri 10/1611:15 am -
1 stop18h 44m
Deal found 9/20![United Airlines logo]()
$837
This BusinessClass deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:30 am -
2 stops22h 00m
Sun 11/16:45 pm -
2 stops29h 59m
Deal found 9/20![Multiple Airlines logo]()
$5,407
This Air Canada deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:35 pm -
3 stops18h 55m
Sun 11/16:00 am -
3 stops23h 59m
Deal found 9/20![Air Canada logo]()
$6,421
This Scandinavian Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:38 pm -
2 stops23h 42m
Sat 10/3112:55 am -
3 stops27h 13m
Deal found 9/20![Scandinavian Airlines logo]()
$10,573
Last-minute flights from Knoxville to SpainDiscover last-minute flight deals from Knoxville to Spain. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Spain. Data last updated September 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:00 am -
2 stops15h 35m
Wed 10/711:10 am -
2 stops28h 24m
Deal found 9/20![Delta logo]()
$612
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:45 am -
1 stop16h 35m
Wed 10/711:15 am -
1 stop29h 22m
Deal found 9/20![United Airlines logo]()
$706
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:40 am -
1 stop25h 10m
Wed 10/711:10 am -
2 stops28h 24m
Deal found 9/20![Delta logo]()
$613
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:25 pm -
2 stops16h 15m
Wed 10/217:00 am -
2 stops22h 59m
Deal found 9/16![Lufthansa logo]()
$712
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:26 am -
2 stops18h 54m
Fri 11/139:20 am -
2 stops20h 39m
Deal found 9/18![Delta logo]()
$584
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:26 am -
2 stops18h 54m
Wed 11/116:00 am -
2 stops22h 12m
Deal found 9/17![Delta logo]()
$608
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:23 pm -
2 stops17h 07m
Fri 11/66:00 am -
2 stops19h 49m
Deal found 9/21![Delta logo]()
$632
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:35 pm -
1 stop31h 10m
Sun 11/156:05 am -
2 stops23h 54m
Deal found 9/17![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:55 pm -
1 stop12h 50m
Wed 11/1111:00 am -
1 stop30h 30m
Deal found 9/17![United Airlines logo]()
$711
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:35 am -
1 stop20h 10m
Fri 11/139:20 am -
2 stops15h 07m
Deal found 9/17![Delta logo]()
$634
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:23 pm -
1 stop10h 22m
Wed 11/1110:50 am -
2 stops16h 39m
Deal found 9/17![Delta logo]()
$653
This United deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:55 pm -
2 stops38h 35m
Thu 11/121:25 pm -
2 stops53h 48m
Deal found 9/17![Multiple Airlines logo]()
$695
One-way flights from Knoxville to SpainSearch for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Knoxville to Spain. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Expedia deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/164:20 pm -
1 stop31h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![British Airways logo]()
$351
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/165:20 pm -
2 stops34h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:01 pm -
3 stops54h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:28 am -
3 stops48h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$433
This Thrive Travel deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 pm -
2 stops21h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Lufthansa logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:04 pm -
3 stops36h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$495
This FlightHub deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:07 pm -
2 stops15h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![British Airways logo]()
$498
This KLM deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:38 pm -
1 stop16h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![KLM logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:01 pm -
3 stops33h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$530
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:00 am -
2 stops35h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:45 pm -
2 stops31h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$592
This TravelUp deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
1 stop16h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Lufthansa logo]()
$624
Find flight deals from Knoxville to Spain
Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated September 21, 2026.
Round-trip from | $584 (Delta) |
|---|---|
One-way from | $351 (Expedia) |
Popular in | July |
Cheapest in | January |
Average price | $1,022 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 1/16
4:20 pm-5:45 am
1 stop31h 25m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$351
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 1/16
6:15 am-8:00 am
3 stops19h 45m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$404
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Wed 10/7
10:28 am-5:25 pm
3 stops48h 57m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$433
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Wed 10/7
7:25 pm-5:55 pm
2 stops16h 30m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$442
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Tue 10/6
7:25 pm-10:25 pm
2 stops21h 00m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$442
Quickest round-trip
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Fri 10/30
5:07 pm-1:40 pm
2 stops15h 33m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$498
KnoxvilleBarcelona
TYS Knoxville McGhee Tyson - BCN Barcelona-El Prat
TYSBCN
Knoxville McGhee Tyson
Tue 10/6
2:38 pm-12:50 pm
1 stop16h 12m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$509
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Mon 12/21
6:33 pm-11:40 pm
3 stops47h 07m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$575
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
7:45 pm-9:30 am
2 stops31h 45m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$592
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Mon 11/9
7:22 pm-5:45 pm
2 stops16h 23m
Madrid Barajas
Tue 11/24
12:20 pm-10:12 pm
1 stop15h 52m
$599
Showing 1-10 of 31 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
TYS-MAD
TYS-BCN
TYS-AGP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Spain
TYS-ES0
TYS-MAD
TYS-BCN
TYS-AGP
What is the cheapest month to book a flight from Knoxville to Spain?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Spain (average of $483). Flying from Knoxville to Spain in June is currently the most expensive (average of $1,477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated September 21, 2026.
See what other customers who have flown with United Airlines,American Airlines, andBritish Airways from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Comfort
7.3
Food
6.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Comfort
7.3
Food
6.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Comfort
7.3
Food
6.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Comfort
7.3
Food
6.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Spain
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Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Spain by cabin class
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Knoxville and Spain flights
Browse other Knoxville and Spain flight options. Last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Spain flights
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Fly to Spain regions
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Top 3 airlines flying from Knoxville to Spain
Discover the top 3 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$432 | Average$930 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$591 | Average$843 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$640 | Average$1,069 | FlexibilityNo cancel fee | On-time71% |