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$439+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
TYS
-
BCN
1 stop24h 15m
United Airlines
Fri 4/2412:15 pm
BCN
-
TYS
2 stops51h 53m
United Airlines
Deal found 2/9$467
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
TYS
-
BCN
1 stop17h 45m
American Airlines
Fri 4/243:30 pm
BCN
-
TYS
1 stop14h 29m
American Airlines
Deal found 2/11$487
This Finnair deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:31 am
TYS
-
MAD
1 stop14h 24m
Multiple Airlines
Tue 4/1411:35 am
MAD
-
TYS
1 stop14h 43m
Multiple Airlines
Deal found 2/11$491
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:49 am
TYS
-
MAD
2 stops16h 11m
United Airlines
Tue 4/1410:50 am
MAD
-
TYS
2 stops14h 52m
United Airlines
Deal found 2/11$496
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:48 pm
TYS
-
BCN
1 stop13h 27m
United Airlines
Fri 5/112:15 pm
BCN
-
TYS
2 stops37h 57m
United Airlines
Deal found 2/10$517
This Gurufare deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:45 am
TYS
-
MAD
1 stop18h 20m
Scandinavian Airlines
Thu 3/2610:05 am
MAD
-
TYS
1 stop12h 40m
Scandinavian Airlines
Deal found 2/10$591
This KLM deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:00 pm
TYS
-
AGP
2 stops20h 35m
Multiple Airlines
Fri 2/276:05 am
AGP
-
TYS
2 stops23h 12m
Multiple Airlines
Deal found 2/10$600
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:05 am
TYS
-
MAD
1 stop20h 10m
Air Europa
Thu 9/2412:45 pm
MAD
-
TYS
2 stops15h 01m
Air Europa
Deal found 2/9$622
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:50 am
TYS
-
MAD
1 stop20h 15m
United Airlines
Fri 9/2511:15 am
MAD
-
TYS
1 stop33h 27m
United Airlines
Deal found 2/9$626
This oojo deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:45 pm
TYS
-
MAD
2 stops24h 20m
British Airways
Sat 10/245:30 pm
MAD
-
TYS
2 stops32h 24m
British Airways
Deal found 2/11$627
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:50 am
TYS
-
MAD
2 stops21h 00m
United Airlines
Thu 9/2411:15 am
MAD
-
TYS
1 stop33h 27m
United Airlines
Deal found 2/11$634
This KLM deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:00 pm
TYS
-
MAD
1 stop18h 15m
Multiple Airlines
Sat 10/242:35 pm
MAD
-
TYS
2 stops15h 11m
Multiple Airlines
Deal found 2/11$635

Find flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated February 12, 2026.

Round-trip from

$467
(United Airlines)

One-way from

$439
(Mytrip)

Popular in

June

Cheapest in

January

Average price

$484
From Knoxville McGhee Tyson to Spain
Search Deals
One-way flight from Knoxville McGhee Tyson to Spain
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($365 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 4/15

5:48 pm-1:15 pm

1 stop13h 27m

Barcelona-El Prat

Fri 4/24

12:15 pm-10:29 pm

2 stops40h 14m

$467

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 4/15

7:00 am-6:45 am

1 stop17h 45m

Barcelona-El Prat

Fri 4/24

3:30 pm-11:59 pm

1 stop14h 29m

$487

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 4/8

11:31 am-7:55 am

1 stop14h 24m

Madrid Barajas

Tue 4/14

11:35 am-8:18 pm

1 stop14h 43m

$491

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 4/8

10:49 am-9:00 am

2 stops16h 11m

Madrid Barajas

Tue 4/14

11:15 am-7:42 pm

1 stop14h 27m

$491

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Fri 4/17

5:48 pm-1:15 pm

1 stop13h 27m

Barcelona-El Prat

Fri 5/1

12:15 pm-8:12 pm

2 stops37h 57m

$517

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/19

8:45 am-8:05 am

1 stop18h 20m

Madrid Barajas

Thu 3/26

10:05 am-5:45 pm

1 stop12h 40m

$591

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 2/26

10:53 am-9:15 am

2 stops16h 22m

Madrid Barajas

Mon 3/2

1:35 pm-8:37 pm

2 stops37h 02m

$676

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 3/1

6:45 am-4:40 pm

2 stops27h 55m

Madrid Barajas

Sun 3/8

5:55 am-9:49 am

2 stops33h 54m

$701

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

9:40 am-1:00 pm

2 stops21h 20m

Madrid Barajas

Fri 3/13

8:35 am-10:49 am

2 stops31h 14m

$712

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 3/6

9:49 am-9:15 am

1 stop17h 26m

Madrid Barajas

Sat 3/14

10:05 am-11:57 pm

1 stop18h 52m

$737

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 24 results
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Spain (average of $181). Flying from Knoxville to Spain in June is currently the most expensive (average of $940). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated February 12, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,181 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,181 reviews
Delta
7.9
Good
8,181 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,279 reviews
Delta
7.9
Good
8,181 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,271 reviews
Delta
7.9
Good
8,181 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,731 reviews
Delta
7.9
Good
8,181 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Spain?

    Airlines like United Airlines, Scandinavian Airlines, and British Airways fly from Knoxville to Spain in about 13h 27m. The time it takes to get you to your destination can typically vary by up to 22h 12m. The distance between Knoxville and Spain is about 4465 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Barcelona-El Prat. You may also consider Knoxville McGhee Tyson - Madrid Barajas or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Spain (average of $181). Flying from Knoxville to Spain in June is currently the most expensive (average of $940). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Spain

Discover the top 4 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$432Average$807FlexibilityNo cancel feeOn-time70%
DeltaCheapest$433Average$1,237FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$512Average$1,007FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$691Average$993FlexibilityNo cancel feeOn-time69%

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