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$339+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:48 pm
TYS
-
BCN
1 stop13h 27m
United Airlines
Fri 4/2412:15 pm
BCN
-
TYS
2 stops40h 14m
United Airlines
Deal found 2/4$467
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:00 am
TYS
-
BCN
2 stops19h 20m
United Airlines
Tue 4/2812:15 pm
BCN
-
TYS
2 stops40h 48m
United Airlines
Deal found 2/3$471
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:53 am
TYS
-
BCN
2 stops16h 07m
United Airlines
Wed 3/1810:30 am
BCN
-
TYS
1 stop29h 19m
United Airlines
Deal found 2/1$474
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
TYS
-
BCN
2 stops23h 05m
British Airways
Wed 4/2210:30 am
BCN
-
TYS
1 stop15h 48m
British Airways
Deal found 2/2$475
This oojo deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
TYS
-
BCN
2 stops23h 05m
British Airways
Fri 4/247:40 am
BCN
-
TYS
2 stops22h 15m
British Airways
Deal found 2/3$485
This Air Canada deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:20 pm
TYS
-
MAD
2 stops29h 30m
Air Canada
Mon 5/412:45 pm
MAD
-
TYS
2 stops31h 49m
Air Canada
Deal found 2/2$525
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:20 pm
TYS
-
MAD
1 stop30h 45m
United Airlines
Mon 5/45:55 am
MAD
-
TYS
2 stops20h 50m
United Airlines
Deal found 2/2$543
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
TYS
-
MAD
2 stops19h 05m
United Airlines
Mon 5/411:15 am
MAD
-
TYS
2 stops15h 30m
United Airlines
Deal found 2/2$546
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:38 pm
TYS
-
MAD
1 stop13h 37m
Delta
Sun 5/32:35 pm
MAD
-
TYS
1 stop27h 15m
Delta
Deal found 2/2$548
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:30 am
TYS
-
MAD
2 stops20h 25m
Delta
Sun 5/32:35 pm
MAD
-
TYS
1 stop27h 15m
Delta
Deal found 2/2$552
This Air Canada deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:40 am
TYS
-
MAD
2 stops39h 10m
Air Canada
Mon 5/412:45 pm
MAD
-
TYS
2 stops38h 00m
Air Canada
Deal found 2/2$581
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:25 pm
TYS
-
MAD
1 stop11h 40m
United Airlines
Sat 5/25:55 am
MAD
-
TYS
2 stops20h 50m
United Airlines
Deal found 2/2$593

Find flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated February 4, 2026.

Round-trip from

$467
(United Airlines)

One-way from

$339
(KAYAK)

Popular in

June

Cheapest in

January

Average price

$484
From Knoxville McGhee Tyson to Spain
Search Deals
One-way flight from Knoxville McGhee Tyson to Spain
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($385 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($55 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Wed 4/15

7:00 am-1:15 pm

1 stop24h 15m

Barcelona-El Prat

Fri 4/24

12:15 pm-10:08 am

2 stops51h 53m

$467

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Tue 4/21

2:25 pm-8:20 am

1 stop11h 55m

Barcelona-El Prat

Tue 4/28

12:15 pm-11:03 pm

2 stops40h 48m

$467

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

Mon 3/2

10:53 am-9:00 am

2 stops16h 07m

Barcelona-El Prat

Wed 3/18

10:30 am-10:49 am

1 stop29h 19m

$474

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 4/28

9:40 am-6:50 am

2 stops15h 10m

Madrid Barajas

Mon 5/4

12:45 pm-8:45 pm

2 stops38h 00m

$525

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 4/26

2:25 pm-8:05 am

1 stop11h 40m

Madrid Barajas

Mon 5/4

5:55 am-8:45 pm

2 stops20h 50m

$543

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 4/25

7:20 pm-8:05 am

1 stop30h 45m

Madrid Barajas

Mon 5/4

5:55 am-8:45 pm

2 stops20h 50m

$543

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 4/28

7:20 pm-8:05 am

1 stop30h 45m

Madrid Barajas

Mon 5/4

5:55 am-8:45 pm

2 stops20h 50m

$543

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 4/27

11:02 am-9:55 am

2 stops16h 53m

Madrid Barajas

Mon 5/4

2:35 pm-11:54 pm

2 stops15h 19m

$546

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 4/27

2:25 pm-8:05 am

1 stop11h 40m

Madrid Barajas

Mon 5/4

11:15 am-10:49 am

1 stop29h 34m

$547

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 4/29

12:03 pm-12:15 pm

1 stop18h 12m

Madrid Barajas

Sun 5/3

2:35 pm-11:50 am

1 stop27h 15m

$548

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 40 results
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Spain (average of $181). Flying from Knoxville to Spain in June is currently the most expensive (average of $940). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated February 4, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,146 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,146 reviews
Delta
7.9
Good
8,146 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,236 reviews
Delta
7.9
Good
8,146 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,222 reviews
Delta
7.9
Good
8,146 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,716 reviews
Delta
7.9
Good
8,146 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Spain?

    Airlines like United Airlines, Air Canada, and Delta fly from Knoxville to Spain in about 15h 10m. The time it takes to get you to your destination can typically vary by up to 9h 05m. The distance between Knoxville and Spain is about 4222 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Barcelona-El Prat. You may also consider Knoxville McGhee Tyson - Madrid Barajas or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Spain (average of $181). Flying from Knoxville to Spain in June is currently the most expensive (average of $940). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Spain

Discover the top 4 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$432Average$805FlexibilityNo cancel feeOn-time70%
DeltaCheapest$433Average$1,237FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$512Average$977FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$691Average$993FlexibilityNo cancel feeOn-time69%

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