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$240+ Cheap flights from Knoxville (TYS) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
gen 7 — gen 141
mer 1/7
mer 1/14
1 adult, Economy
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Cheap flight deals from Knoxville to Spain

Cheapest flights from Knoxville to Spain
Explore the most affordable flight options available from Knoxville to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on dicembre 8, 2025.

This oojo deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/2810:49 amTYS - MAD
2 stops19h 06mBritish Airways
lun 1/1212:50 pmMAD - TYS
2 stops39h 19mBritish Airways
Deal found 12/7$862
This Finnair deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/285:15 amTYS - MAD
1 stop18h 35mMultiple Airlines
lun 1/1212:00 pmMAD - TYS
1 stop16h 09mMultiple Airlines
Deal found 12/7$869
This Finnair deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/285:15 amTYS - MAD
1 stop18h 35mMultiple Airlines
ven 1/97:40 amMAD - TYS
2 stops21h 07mMultiple Airlines
Deal found 12/6$1,039
This Finnair deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/1411:00 amTYS - MAD
1 stop12h 45mMultiple Airlines
gio 1/81:15 pmMAD - TYS
1 stop13h 41mMultiple Airlines
Deal found 12/7$1,191
This Ovago deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/2810:49 amTYS - MAD
2 stops19h 06mBritish Airways
ven 1/96:45 amMAD - TYS
2 stops18h 01mBritish Airways
Deal found 12/7$1,238
This Delta deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/286:59 pmTYS - MAD
2 stops18h 41mDelta
ven 1/910:00 amMAD - TYS
2 stops19h 45mDelta
Deal found 12/6$1,256
This oojo deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/147:00 amTYS - MAD
1 stop19h 55mBritish Airways
gio 1/84:45 pmMAD - TYS
2 stops34h 11mBritish Airways
Deal found 12/7$1,338
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/145:40 amTYS - MAD
2 stops20h 20mDelta
gio 1/810:00 amMAD - TYS
2 stops19h 45mDelta
Deal found 12/7$1,395
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/289:50 amTYS - BCN
1 stop16h 30mUnited Airlines
dom 1/411:55 amBCN - TYS
2 stops42h 04mUnited Airlines
Deal found 12/7$1,632
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 12/237:15 amTYS - BCN
2 stops30h 35mMultiple Airlines
sab 12/276:10 pmBCN - TYS
1 stop23h 21mMultiple Airlines
Deal found 12/7$1,649
This KLM deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 12/236:59 pmTYS - BCN
1 stop31h 41mKLM
sab 12/2710:55 amBCN - TYS
1 stop16h 20mKLM
Deal found 12/7$1,676
This Finnair deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/285:15 amTYS - BCN
1 stop19h 50mMultiple Airlines
dom 1/411:00 amBCN - TYS
1 stop19h 38mMultiple Airlines
Deal found 12/7$1,909

Find flight deals from Knoxville to Spain

Keep the following information in mind while searching for Knoxville to Spain flight deals. Data was last updated dicembre 8, 2025.

Round-trip from

$468
(United Airlines)

One-way from

$240
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$894
From Knoxville McGhee Tyson to Spain
Search Deals
One-way flight from Knoxville McGhee Tyson to Spain
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($360 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($58 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dicembre 8, 2025.
Use the filters below to find and compare flights from Knoxville to Spain that are best for you.

Fly from

Knoxville

Fly to

Spain

Route

Depart

Return

Price

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

lun 1/19

6:45 am-9:35 am

2 stops20h 50m

Barcelona-El Prat

lun 1/26

1:35 pm-7:27 pm

2 stops35h 52m

$468

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

ven 2/6

6:45 am-9:00 am

2 stops20h 15m

Barcelona-El Prat

mar 2/10

1:35 pm-2:49 pm

2 stops31h 14m

$469

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

sab 1/31

2:19 pm-5:55 pm

2 stops21h 36m

Barcelona-El Prat

mer 2/11

12:30 pm-8:56 pm

1 stop14h 26m

$472

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

ven 1/23

1:59 pm-9:15 am

2 stops13h 16m

Madrid Barajas

mar 1/27

1:35 pm-2:49 pm

2 stops31h 14m

$473

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

lun 1/19

12:19 pm-8:50 am

1 stop14h 31m

Barcelona-El Prat

lun 1/26

12:30 pm-8:56 pm

1 stop14h 26m

$484

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

lun 1/19

6:00 am-8:50 am

1 stop20h 50m

Barcelona-El Prat

lun 1/26

12:30 pm-8:56 pm

1 stop14h 26m

$484

KnoxvilleBarcelona

TYS - BCN

TYSBCN

Knoxville McGhee Tyson

sab 2/14

10:41 am-8:50 am

1 stop16h 09m

Barcelona-El Prat

sab 2/21

10:40 am-9:39 pm

1 stop16h 59m

$484

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

dom 3/8

6:05 am-7:00 am

1 stop19h 55m

Madrid Barajas

lun 3/30

6:00 am-11:51 pm

2 stops23h 51m

$640

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

mar 4/28

11:55 am-7:50 am

1 stop13h 55m

Madrid Barajas

ven 9/18

10:05 am-6:17 pm

1 stop14h 12m

$647

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

mar 3/17

2:38 pm-8:05 am

1 stop12h 27m

Madrid Barajas

ven 4/17

10:05 am-6:15 pm

1 stop14h 10m

$647

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 28 results
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Best time to book a flight from Knoxville to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spain

What is the cheapest month to book a flight from Knoxville to Spain?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Spain (average of $181). Flying from Knoxville to Spain in June is currently the most expensive (average of $919). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ES?

Find hourly flight availability from Knoxville to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated dicembre 8, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Spain in the evening. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated dicembre 8, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Spain have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,078 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,044 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,564 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spain?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Spain. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Spain?

    Airlines like United Airlines, British Airways, and Delta fly from Knoxville to Spain in about 19h 55m. The time it takes to get you to your destination can typically vary by up to 1h 41m. The distance between Knoxville and Spain is about 4222 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Spain?

    The most popular route from Knoxville to Spain is Knoxville McGhee Tyson - Madrid Barajas. You may also consider Knoxville McGhee Tyson - Barcelona-El Prat or Knoxville McGhee Tyson - Malaga.

  • Can I find deals for flights from Knoxville to Spain that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spain.

  • Can I find deals for business class flights from Knoxville to Spain?

    Yes. Cheapflights offers flight deals from Knoxville to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spain?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Spain (average of $181). Flying from Knoxville to Spain in June is currently the most expensive (average of $919). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Spain

Discover the top 4 airlines that operate flights from Knoxville to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dicembre 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$433Average$1,276FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$605Average$1,183FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$632Average$864FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$732Average$1,106FlexibilityNo cancel feeOn-time69%

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