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$48+ Cheap flights from Wilkes-Barre, PA to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to South Carolina

Keep the following information in mind while searching for Wilkes-Barre to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$102
(Priceline)

One-way from

$48
(Kiwi.com)

Popular in

April

Cheapest in

June

Average price

$272
Provider with most accurate pricing for Wilkes-Barre Scranton-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Myrtle Beach Intl flights.
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From Wilkes-Barre to South Carolina
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One-way flight from Wilkes-Barre to South Carolina
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Highest demand for flights based on searches. 32% potential increase in price ($158 potential increase over avg. RT price).
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Cheapest flight prices on average. 15% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Wilkes-Barre to South Carolina

Cheapest flights from Wilkes-Barre to South Carolina
Explore the most affordable flight options available from Wilkes-Barre to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:49 amAVP - MYR
Nonstop1h 45mBreeze Airways
Fri 12/129:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 10/28$102
This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:49 amAVP - MYR
Nonstop1h 45mBreeze Airways
Fri 11/149:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 10/28$105
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:49 amAVP - MYR
Nonstop1h 45mBreeze Airways
Fri 11/79:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 10/28$115
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:54 pmAVP - CLT
Nonstop1h 52mAmerican Airlines
Sat 12/133:01 pmCLT - AVP
Nonstop1h 40mAmerican Airlines
Deal found 10/30$199
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:21 amAVP - MYR
1 stop23h 23mBreeze Airways
Mon 12/89:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 10/28$201
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:36 pmAVP - MYR
2 stops37h 13mMultiple Airlines
Fri 12/129:24 amMYR - AVP
Nonstop1h 45mMultiple Airlines
Deal found 10/28$211
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:25 pmAVP - CHS
1 stop4h 52mAmerican Airlines
Wed 11/197:12 pmCHS - AVP
1 stop3h 58mAmerican Airlines
Deal found 10/29$214
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:49 amAVP - MYR
Nonstop1h 45mMultiple Airlines
Mon 11/246:15 amMYR - AVP
1 stop28h 57mMultiple Airlines
Deal found 10/29$216
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amAVP - CLT
Nonstop2h 01mAmerican Airlines
Sat 12/68:57 amCLT - AVP
Nonstop1h 47mAmerican Airlines
Deal found 10/29$234
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:49 pmAVP - CHS
1 stop3h 55mAmerican Airlines
Wed 11/196:10 amCHS - AVP
1 stop5h 53mAmerican Airlines
Deal found 10/29$244
This Cheapflightsfares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:49 amAVP - MYR
Nonstop1h 45mBreeze Airways
Mon 11/249:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 10/28$249
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:49 amAVP - MYR
Nonstop1h 45mMultiple Airlines
Fri 11/142:46 pmMYR - AVP
2 stops23h 13mMultiple Airlines
Deal found 10/28$252

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Wilkes-Barre to South Carolina that are best for you.

Fly from

Wilkes-Barre

Fly to

South Carolina

Route

Depart

Return

Price

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 11/10

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Fri 11/14

9:24 am-11:09 am

Nonstop1h 45m

$105

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 12/8

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Fri 12/12

9:24 am-11:09 am

Nonstop1h 45m

$112

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Fri 11/21

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Mon 11/24

9:24 am-11:09 am

Nonstop1h 45m

$127

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Thu 12/4

9:21 am-8:44 am

1 stop23h 23m

Myrtle Beach Intl

Mon 12/8

9:24 am-11:09 am

Nonstop1h 45m

$201

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Sat 11/15

5:25 pm-10:17 pm

1 stop4h 52m

Charleston

Wed 11/19

7:12 pm-11:10 pm

1 stop3h 58m

$214

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 12/8

7:36 pm-8:00 am

2 stops36h 24m

Myrtle Beach Intl

Fri 12/12

9:24 am-11:09 am

Nonstop1h 45m

$215

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Fri 11/21

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Mon 11/24

6:15 am-11:12 am

1 stop28h 57m

$216

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Fri 11/14

12:49 pm-4:44 pm

1 stop3h 55m

Charleston

Wed 11/19

6:10 am-12:03 pm

1 stop5h 53m

$244

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Wed 2/11

10:35 am-2:48 pm

1 stop4h 13m

Charleston

Sat 2/14

2:48 pm-6:48 pm

1 stop4h 00m

$249

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 3/10

6:00 am-10:04 am

1 stop4h 04m

Charleston

Tue 3/17

2:30 pm-6:47 pm

1 stop4h 17m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 50 results
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Best time to book a flight from Wilkes-Barre to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to South Carolina

What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $114). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to SC?

Find hourly flight availability from Wilkes-Barre to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Wilkes-Barre to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

What is the cheapest day to fly from Wilkes-Barre to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Wilkes-Barre to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Wilkes-Barre to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2025.
See what other customers who have flown with Breeze Airways, United Airlines, and American Airlines from Wilkes-Barre to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
222 reviews

Crew

8.7

Comfort

8.2

Food

6.7

Entertainment

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
Breeze Airways
8.1
Very good
222 reviews
Breeze Airways
8.1
Very good
222 reviews

Crew

8.7

Comfort

8.2

Food

6.7

Entertainment

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
United Airlines
7.4
Good
8,998 reviews
Breeze Airways
8.1
Very good
222 reviews

Crew

8.7

Comfort

8.2

Food

6.7

Entertainment

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
American Airlines
7.2
Good
11,034 reviews
Breeze Airways
8.1
Very good
222 reviews

Crew

8.7

Comfort

8.2

Food

6.7

Entertainment

6.6

Boarding

8.3

Overall

8.1

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilkes-Barre to South Carolina?

    Departing from Wilkes-Barre to South Carolina will take you 1h 45m. The distance from Wilkes-Barre to South Carolina is about 557 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Wilkes-Barre to South Carolina?

    Most travelers choose Wilkes-Barre Scranton - Charlotte Douglas, Wilkes-Barre Scranton - Myrtle Beach Intl or Wilkes-Barre Scranton - Charleston when deciding on the best route from Wilkes-Barre to South Carolina.

  • Can I find deals for flights from Wilkes-Barre to South Carolina that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to South Carolina.

  • Can I find deals for business class flights from Wilkes-Barre to South Carolina?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

    Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $114). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Wilkes-Barre to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Wilkes-Barre to South Carolina

Discover the top 5 airlines that operate flights from Wilkes-Barre to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$93Average$158FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$111Average$145FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$178Average$466FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$364FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$496FlexibilityNo cancel feeOn-timeN/A

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