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South Carolina

$74+ Cheap flights from Wilkes-Barre, PA to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — CHS
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to South Carolina

Cheapest flights from Wilkes-Barre to South Carolina
Explore the most affordable flight options available from Wilkes-Barre to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:21 pmAVP - CLT
Nonstop2h 01mAmerican Airlines
Fri 1/99:45 pmCLT - AVP
Nonstop1h 41mAmerican Airlines
Deal found 12/15$328
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amAVP - SAV
1 stop6h 13mAmerican Airlines
Sun 12/215:05 amSAV - AVP
1 stop5h 44mAmerican Airlines
Deal found 12/15$348
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:21 pmAVP - CLT
Nonstop2h 01mAmerican Airlines
Sun 1/189:43 pmCLT - AVP
Nonstop1h 41mAmerican Airlines
Deal found 12/17$354
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:32 pmAVP - CLT
1 stop24h 07mMultiple Airlines
Mon 12/299:34 pmCLT - AVP
1 stop22h 18mMultiple Airlines
Deal found 12/16$356
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amAVP - CLT
Nonstop2h 07mAmerican Airlines
Sat 1/39:58 pmCLT - AVP
Nonstop1h 45mAmerican Airlines
Deal found 12/17$357
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amAVP - SAV
1 stop6h 24mAmerican Airlines
Tue 12/235:05 amSAV - AVP
1 stop5h 44mAmerican Airlines
Deal found 12/17$366
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:54 pmAVP - MYR
1 stop6h 08mAmerican Airlines
Mon 12/227:46 pmMYR - AVP
1 stop3h 57mAmerican Airlines
Deal found 12/15$378
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amAVP - CLT
Nonstop2h 07mAmerican Airlines
Mon 12/299:00 amCLT - AVP
Nonstop1h 49mAmerican Airlines
Deal found 12/15$383
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:39 pmAVP - CLT
1 stop22h 58mMultiple Airlines
Fri 1/96:00 pmCLT - AVP
1 stop20h 01mMultiple Airlines
Deal found 12/15$389
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:19 amAVP - CLT
Nonstop1h 54mAmerican Airlines
Sat 12/279:58 pmCLT - AVP
Nonstop1h 45mAmerican Airlines
Deal found 12/16$391
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:31 amAVP - GSP
1 stop3h 44mUnited Airlines
Sat 1/38:34 amGSP - AVP
1 stop7h 51mUnited Airlines
Deal found 12/17$394
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amAVP - CLT
Nonstop2h 07mAmerican Airlines
Fri 12/269:58 pmCLT - AVP
Nonstop1h 45mAmerican Airlines
Deal found 12/17$399

Find flight deals from Wilkes-Barre to South Carolina

Keep the following information in mind while searching for Wilkes-Barre to South Carolina flight deals. Data was last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$199
(American Airlines)

One-way from

$74
(Kiwi.com)

Popular in

April

Cheapest in

June

Average price

$213
Provider with most accurate pricing for Wilkes-Barre Scranton-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Myrtle Beach Intl flights.
Search Deals
From Wilkes-Barre to South Carolina
Search Deals
One-way flight from Wilkes-Barre to South Carolina
Search Deals
Highest demand for flights based on searches. 40% potential increase in price ($204 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 17% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Wilkes-Barre to South Carolina that are best for you.

Fly from

Wilkes-Barre

Fly to

South Carolina

Route

Depart

Return

Price

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Wed 1/28

12:50 pm-2:49 pm

Nonstop1h 59m

Charlotte Douglas

Sat 1/31

10:25 am-12:05 pm

Nonstop1h 40m

$199

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 1/5

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Sat 1/10

3:39 pm-9:43 am

2 stops42h 04m

$208

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Sat 1/17

12:50 pm-2:49 pm

Nonstop1h 59m

Charlotte Douglas

Sun 1/18

10:25 am-12:05 pm

Nonstop1h 40m

$251

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Sat 1/17

12:50 pm-4:55 pm

1 stop4h 05m

Savannah/Hilton Head

Wed 1/21

7:00 am-12:05 pm

1 stop5h 05m

$268

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 2/24

10:35 am-2:49 pm

1 stop4h 14m

Charleston

Tue 3/3

2:48 pm-6:48 pm

1 stop4h 00m

$269

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Wed 3/4

2:45 pm-9:27 pm

1 stop6h 42m

Charleston

Wed 3/11

2:48 pm-6:27 pm

1 stop3h 39m

$269

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 3/10

6:30 am-1:52 pm

1 stop7h 22m

Charleston

Tue 3/17

8:15 am-1:57 pm

1 stop5h 42m

$269

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 3/24

10:32 am-2:54 pm

1 stop4h 22m

Charleston

Sat 3/28

6:00 am-1:53 pm

1 stop7h 53m

$269

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 2/24

4:30 pm-11:01 pm

1 stop6h 31m

Charleston

Tue 3/3

7:45 pm-11:58 pm

1 stop4h 13m

$271

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Fri 1/16

6:57 am-9:00 am

Nonstop2h 03m

Charlotte Douglas

Fri 1/23

10:25 am-12:05 pm

Nonstop1h 40m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 54 results
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Best time to book a flight from Wilkes-Barre to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to South Carolina

What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $114). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to SC?

Find hourly flight availability from Wilkes-Barre to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

One of the essential ways to save on airfare from Wilkes-Barre to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

What is the cheapest day to fly from Wilkes-Barre to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Wilkes-Barre to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Wilkes-Barre to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 17, 2025.
See what other customers who have flown with Breeze Airways, United Airlines, and American Airlines from Wilkes-Barre to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
248 reviews

Comfort

8.2

Entertainment

6.7

Boarding

8.4

Crew

8.8

Overall

8.2

Food

6.7

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Breeze Airways
8.2
Very good
248 reviews
Breeze Airways
8.2
Very good
248 reviews

Comfort

8.2

Entertainment

6.7

Boarding

8.4

Crew

8.8

Overall

8.2

Food

6.7

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
United Airlines
7.4
Good
9,092 reviews
Breeze Airways
8.2
Very good
248 reviews

Comfort

8.2

Entertainment

6.7

Boarding

8.4

Crew

8.8

Overall

8.2

Food

6.7

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
American Airlines
7.2
Good
11,053 reviews
Breeze Airways
8.2
Very good
248 reviews

Comfort

8.2

Entertainment

6.7

Boarding

8.4

Crew

8.8

Overall

8.2

Food

6.7

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilkes-Barre to South Carolina?

    Departing from Wilkes-Barre to South Carolina will take you 1h 59m. The distance from Wilkes-Barre to South Carolina is about 508 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Wilkes-Barre to South Carolina?

    Most travelers choose Wilkes-Barre Scranton - Myrtle Beach Intl, Wilkes-Barre Scranton - Charlotte Douglas or Wilkes-Barre Scranton - Charleston when deciding on the best route from Wilkes-Barre to South Carolina.

  • Can I find deals for flights from Wilkes-Barre to South Carolina that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to South Carolina.

  • Can I find deals for business class flights from Wilkes-Barre to South Carolina?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

    Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $114). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Wilkes-Barre to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Wilkes-Barre to South Carolina

Discover the top 5 airlines that operate flights from Wilkes-Barre to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$95Average$158FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$108Average$147FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$178Average$462FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$481FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$223Average$362FlexibilityNo cancel feeOn-time69%

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