HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$98+ Cheap flights from Wilkes-Barre, PA to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — CHS
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Wilkes-Barre to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Wilkes-Barre to South Carolina

Keep the following information in mind while searching for Wilkes-Barre to South Carolina flight deals. Data was last updated September 16, 2025.

Round-trip from

$98
(Breeze Airways)

Popular in

April

Cheapest in

June

Average price

$218
From Wilkes-Barre to South Carolina
Search Deals
Highest demand for flights based on searches. 31% potential increase in price ($154 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Wilkes-Barre to South Carolina

Cheapest flights from Wilkes-Barre to South Carolina
Explore the most affordable flight options available from Wilkes-Barre to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Breeze Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:49 amAVP - MYR
Nonstop1h 45mBreeze Airways
Fri 11/149:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 9/15$98
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:32 pmAVP - CHS
1 stop4h 07mAmerican Airlines
Wed 11/56:10 amCHS - AVP
1 stop5h 53mAmerican Airlines
Deal found 9/14$189
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:21 amAVP - MYR
1 stop23h 23mBreeze Airways
Mon 11/39:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 9/15$203
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:36 pmAVP - MYR
1 stop23h 59mMultiple Airlines
Fri 11/149:24 amMYR - AVP
Nonstop1h 45mMultiple Airlines
Deal found 9/15$208
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:49 amAVP - CLT
2 stops7h 16mMultiple Airlines
Sat 10/43:34 pmCLT - AVP
1 stop17h 07mMultiple Airlines
Deal found 9/14$216
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:21 amAVP - CLT
1 stop26h 22mMultiple Airlines
Sat 10/43:34 pmCLT - AVP
1 stop17h 07mMultiple Airlines
Deal found 9/14$218
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:49 amAVP - MYR
Nonstop1h 45mBreeze Airways
Mon 11/39:24 amMYR - AVP
Nonstop1h 45mBreeze Airways
Deal found 9/14$230
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amAVP - CLT
Nonstop1h 51mAmerican Airlines
Sat 11/158:36 pmCLT - AVP
Nonstop1h 46mAmerican Airlines
Deal found 9/14$234
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:21 amAVP - CLT
1 stop26h 22mMultiple Airlines
Fri 10/38:51 pmCLT - AVP
1 stop17h 08mMultiple Airlines
Deal found 9/14$240
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/297:36 pmAVP - CHS
1 stop13h 01mBreeze Airways
Fri 10/32:39 pmCHS - AVP
1 stop19h 18mBreeze Airways
Deal found 9/14$241
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/67:36 pmAVP - MYR
1 stop13h 51mMultiple Airlines
Fri 10/109:24 amMYR - AVP
Nonstop1h 45mMultiple Airlines
Deal found 9/14$242
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:16 pmAVP - CLT
1 stop13h 46mAmerican Airlines
Tue 11/410:20 amCLT - AVP
Nonstop1h 43mAmerican Airlines
Deal found 9/15$243

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Wilkes-Barre to South Carolina that are best for you.

Fly from

Wilkes-Barre

Fly to

South Carolina

Route

Depart

Return

Price

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 11/10

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Fri 11/14

9:24 am-11:09 am

Nonstop1h 45m

$98

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 11/4

12:49 pm-4:44 pm

1 stop3h 55m

Charleston

Tue 11/11

8:00 am-12:03 pm

1 stop4h 03m

$189

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Thu 10/30

9:21 am-8:44 am

1 stop23h 23m

Myrtle Beach Intl

Mon 11/3

9:24 am-11:09 am

Nonstop1h 45m

$203

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Thu 10/2

9:21 am-11:43 am

1 stop26h 22m

Charlotte Douglas

Fri 10/3

8:51 pm-1:59 pm

1 stop17h 08m

$240

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Mon 9/29

7:36 pm-8:37 am

1 stop13h 01m

Charleston

Fri 10/3

2:39 pm-9:57 am

1 stop19h 18m

$241

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 10/6

7:36 pm-9:27 am

1 stop13h 51m

Myrtle Beach Intl

Fri 10/10

9:24 am-11:09 am

Nonstop1h 45m

$242

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Mon 11/3

6:16 pm-8:02 am

1 stop13h 46m

Charlotte Douglas

Tue 11/4

10:20 am-12:03 pm

Nonstop1h 43m

$243

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 9/29

11:49 am-1:34 pm

Nonstop1h 45m

Myrtle Beach Intl

Sun 10/5

7:43 pm-6:56 pm

1 stop23h 13m

$244

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Mon 11/10

7:36 pm-10:41 am

2 stops15h 05m

Myrtle Beach Intl

Fri 11/14

9:24 am-11:09 am

Nonstop1h 45m

$245

ScrantonHilton Head Island

AVP - HHH

AVPHHH

Wilkes-Barre Scranton

Tue 11/11

6:00 am-12:29 pm

1 stop6h 29m

Hilton Head Island

Tue 11/18

7:07 pm-11:10 pm

1 stop4h 03m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 54 results
1
2
3
...
6

Best time to book a flight from Wilkes-Barre to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to South Carolina

What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $217). Flying from Wilkes-Barre to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to SC?

Find hourly flight availability from Wilkes-Barre to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Wilkes-Barre to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 16, 2025.
See what other customers who have flown with Breeze Airways, United Airlines, and American Airlines from Wilkes-Barre to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.0
Very good
205 reviews

Crew

8.7

Entertainment

6.5

Comfort

8.1

Overall

8.0

Boarding

8.2

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
Breeze Airways
8.0
Very good
205 reviews
Breeze Airways
8.0
Very good
205 reviews

Crew

8.7

Entertainment

6.5

Comfort

8.1

Overall

8.0

Boarding

8.2

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
United Airlines
7.4
Good
8,929 reviews
Breeze Airways
8.0
Very good
205 reviews

Crew

8.7

Entertainment

6.5

Comfort

8.1

Overall

8.0

Boarding

8.2

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.0
Very good
205 reviews

Crew

8.7

Entertainment

6.5

Comfort

8.1

Overall

8.0

Boarding

8.2

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilkes-Barre to South Carolina?

    Departing from Wilkes-Barre to South Carolina will take you 1h 45m. The distance from Wilkes-Barre to South Carolina is about 557 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Wilkes-Barre to South Carolina?

    Most travelers choose Wilkes-Barre Scranton - Charlotte Douglas, Wilkes-Barre Scranton - Myrtle Beach Intl or Wilkes-Barre Scranton - Charleston when deciding on the best route from Wilkes-Barre to South Carolina.

  • Can I find deals for flights from Wilkes-Barre to South Carolina that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to South Carolina.

  • Can I find deals for business class flights from Wilkes-Barre to South Carolina?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $217). Flying from Wilkes-Barre to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Wilkes-Barre to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Miami flights
LaGuardia to Dallas/Fort Worth flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to O'Hare Intl flights
Newark to Las Vegas flights
LaGuardia to O'Hare Intl flights
LaGuardia to Fort Lauderdale flights
Newark to O'Hare Intl flights
Newark to Miami flights
John F Kennedy Intl to Atlanta flights
John F Kennedy Intl to Orlando flights
Newark to Dallas/Fort Worth flights
John F Kennedy Intl to Dallas/Fort Worth flights
John F Kennedy Intl to San Francisco flights
Newark to Los Angeles flights
LaGuardia to Miami flights
Newark to Orlando flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Sky Harbor Intl flights
Dulles Intl to Dallas/Fort Worth flights
John F Kennedy Intl to Hobby flights
LaGuardia to Orlando flights
Newark to Hobby flights
John F Kennedy Intl to New Orleans flights
Newark to Sky Harbor Intl flights
Newark to San Francisco flights
LaGuardia to Los Angeles flights
John F Kennedy Intl to Denver flights
LaGuardia to Hobby flights
LaGuardia to Las Vegas flights
LaGuardia to Atlanta flights
Dulles Intl to Los Angeles flights
Reagan-National to Dallas/Fort Worth flights
Reagan-National to Los Angeles flights
Dulles Intl to Atlanta flights
LaGuardia to New Orleans flights
Dulles Intl to Las Vegas flights
Philadelphia to Orlando flights
Dulles Intl to Orlando flights
John F Kennedy Intl to George Bush Intcntl flights
Reagan-National to O'Hare Intl flights
John F Kennedy Intl to West Palm Beach flights
Newark to Denver flights
LaGuardia to Denver flights
Dulles Intl to Boston flights
Dulles Intl to O'Hare Intl flights
Newark to Atlanta flights
John F Kennedy Intl to Austin flights

Top 5 airlines flying from Wilkes-Barre to South Carolina

Discover the top 5 airlines that operate flights from Wilkes-Barre to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$92Average$158FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$108Average$148FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$180Average$460FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$364FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$494FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.