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South Carolina

$109+ Cheap flights from Wilkes-Barre, PA to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — CHS
Apr 23 — Apr 301
Thu 4/23
Thu 4/30
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to South Carolina

Cheapest flights from Wilkes-Barre to South Carolina
Explore the most affordable flight options available from Wilkes-Barre to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:13 pm
AVP
-
MYR
Nonstop1h 49m
Breeze Airways
Wed 9/99:25 am
MYR
-
AVP
Nonstop1h 52m
Breeze Airways
Deal found 3/22$123
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:13 pm
AVP
-
MYR
Nonstop1h 49m
Breeze Airways
Sat 5/309:45 am
MYR
-
AVP
Nonstop1h 48m
Breeze Airways
Deal found 3/22$157
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:37 am
AVP
-
MYR
1 stop11h 50m
Multiple Airlines
Wed 9/99:25 am
MYR
-
AVP
Nonstop1h 52m
Multiple Airlines
Deal found 3/22$192
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:13 pm
AVP
-
MYR
Nonstop1h 49m
Breeze Airways
Wed 5/279:45 am
MYR
-
AVP
Nonstop1h 48m
Breeze Airways
Deal found 3/23$197
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:13 pm
AVP
-
MYR
Nonstop1h 49m
Breeze Airways
Wed 6/39:45 am
MYR
-
AVP
Nonstop1h 48m
Breeze Airways
Deal found 3/21$208
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:57 am
AVP
-
MYR
Nonstop1h 53m
Breeze Airways
Sun 9/206:25 pm
MYR
-
AVP
1 stop14h 38m
Breeze Airways
Deal found 3/23$266
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:29 pm
AVP
-
CLT
1 stop14h 37m
American Airlines
Sun 4/269:05 am
CLT
-
AVP
Nonstop2h 08m
American Airlines
Deal found 3/22$283
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:25 pm
AVP
-
SAV
1 stop5h 43m
United Airlines
Sat 5/212:18 pm
SAV
-
AVP
1 stop8h 38m
United Airlines
Deal found 3/23$295
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:19 pm
AVP
-
CHS
1 stop6h 45m
United Airlines
Tue 11/1010:23 am
CHS
-
AVP
1 stop3h 28m
United Airlines
Deal found 3/24$301
This Breeze Airways deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2512:13 pm
AVP
-
MYR
Nonstop1h 49m
Breeze Airways
Sat 8/19:45 am
MYR
-
AVP
Nonstop1h 48m
Breeze Airways
Deal found 3/22$308
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/183:25 pm
AVP
-
SAV
1 stop5h 43m
United Airlines
Tue 4/215:45 am
SAV
-
AVP
1 stop4h 03m
United Airlines
Deal found 3/21$312
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:59 pm
AVP
-
CHS
1 stop4h 00m
United Airlines
Tue 5/127:44 pm
CHS
-
AVP
1 stop3h 35m
United Airlines
Deal found 3/21$315

Find flight deals from Wilkes-Barre to South Carolina

Keep the following information in mind while searching for Wilkes-Barre to South Carolina flight deals. Data was last updated March 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$123
(Kiwi.com)

One-way from

$109
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$522
Provider with most accurate pricing for Wilkes-Barre Scranton-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Myrtle Beach Intl flights.
Search Deals
From Wilkes-Barre to South Carolina
Search Deals
One-way flight from Wilkes-Barre to South Carolina
Search Deals
Highest demand for flights based on searches. 38% potential increase in price ($168 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Sat 4/25

3:25 pm-9:08 pm

1 stop5h 43m

Savannah/Hilton Head

Sat 5/2

12:18 pm-8:56 pm

1 stop8h 38m

$295

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Sat 4/18

3:25 pm-9:25 pm

1 stop6h 00m

Charleston

Wed 4/22

6:00 am-9:48 am

1 stop3h 48m

$329

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Tue 4/21

6:00 am-11:29 am

1 stop5h 29m

Myrtle Beach Intl

Tue 4/28

6:30 pm-11:48 pm

1 stop5h 18m

$353

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Tue 4/7

5:12 pm-9:46 pm

1 stop4h 34m

Charleston

Sat 4/11

5:00 am-11:18 am

1 stop6h 18m

$371

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Sat 5/2

3:10 pm-9:13 pm

1 stop6h 03m

Savannah/Hilton Head

Wed 5/6

8:01 am-2:12 pm

1 stop6h 11m

$375

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Sat 5/2

7:59 pm-11:59 pm

1 stop4h 00m

Charleston

Wed 5/6

7:44 pm-11:19 pm

1 stop3h 35m

$381

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Thu 5/7

7:59 pm-11:59 pm

1 stop4h 00m

Charlotte Douglas

Sat 5/9

7:43 pm-11:19 pm

1 stop3h 36m

$407
Quickest round-trip

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Wed 7/8

10:35 am-2:12 pm

1 stop3h 37m

Charlotte Douglas

Sat 7/11

6:00 am-9:48 am

1 stop3h 48m

$407

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Thu 9/17

8:59 pm-8:45 am

1 stop11h 46m

Myrtle Beach Intl

Sun 9/20

6:25 pm-9:03 am

1 stop14h 38m

$408

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Thu 5/7

7:59 pm-11:59 pm

1 stop4h 00m

Savannah/Hilton Head

Sun 5/10

5:45 am-9:48 am

1 stop4h 03m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Wilkes-Barre to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to South Carolina

What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to SC?

Find hourly flight availability from Wilkes-Barre to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 24, 2026.

One of the essential ways to save on airfare from Wilkes-Barre to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 22% on airfare.

How much does it cost to fly round-trip from Wilkes-Barre to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 24, 2026.
See what other customers who have flown with Breeze Airways,United Airlines, andAmerican Airlines from Wilkes-Barre to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
273 reviews

Entertainment

6.6

Boarding

8.3

Food

6.6

Overall

8.1

Comfort

8.2

Crew

8.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
Breeze Airways
8.1
Very good
273 reviews
Breeze Airways
8.1
Very good
273 reviews

Entertainment

6.6

Boarding

8.3

Food

6.6

Overall

8.1

Comfort

8.2

Crew

8.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
United Airlines
7.4
Good
9,469 reviews
Breeze Airways
8.1
Very good
273 reviews

Entertainment

6.6

Boarding

8.3

Food

6.6

Overall

8.1

Comfort

8.2

Crew

8.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.
American Airlines
7.1
Good
11,491 reviews
Breeze Airways
8.1
Very good
273 reviews

Entertainment

6.6

Boarding

8.3

Food

6.6

Overall

8.1

Comfort

8.2

Crew

8.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilkes-Barre to South Carolina?

    Departing from Wilkes-Barre to South Carolina will take you 5h 29m. The distance from Wilkes-Barre to South Carolina is about 557 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Wilkes-Barre to South Carolina?

    Most travelers choose Wilkes-Barre Scranton - Charlotte Douglas, Wilkes-Barre Scranton - Charleston or Wilkes-Barre Scranton - Myrtle Beach Intl when deciding on the best route from Wilkes-Barre to South Carolina.

  • Can I find deals for flights from Wilkes-Barre to South Carolina that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to South Carolina.

  • Can I find deals for business class flights from Wilkes-Barre to South Carolina?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

    Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Wilkes-Barre to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Wilkes-Barre to South Carolina

Discover the top 5 airlines that operate flights from Wilkes-Barre to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$96Average$162FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$100Average$150FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$178Average$471FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$467FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$223Average$436FlexibilityNo cancel feeOn-time69%

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