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South Carolina

$124+ Cheap flights from Wilkes-Barre, PA to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to South Carolina

Cheapest flights from Wilkes-Barre to South Carolina
Explore the most affordable flight options available from Wilkes-Barre to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:13 pm
AVP
-
MYR
Nonstop1h 49m
Breeze Airways
Sat 5/99:45 am
MYR
-
AVP
Nonstop1h 48m
Breeze Airways
Deal found 1/27$188
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/32:45 pm
AVP
-
CHS
1 stop6h 42m
United Airlines
Tue 3/107:47 pm
CHS
-
AVP
1 stop3h 30m
United Airlines
Deal found 1/27$261
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:13 pm
AVP
-
CHS
2 stops20h 25m
Breeze Airways
Sat 9/58:56 pm
CHS
-
AVP
1 stop11h 56m
Breeze Airways
Deal found 1/27$264
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
AVP
-
GSP
1 stop3h 58m
United Airlines
Sat 4/187:42 pm
GSP
-
AVP
1 stop4h 02m
United Airlines
Deal found 1/26$269
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:55 pm
AVP
-
CHS
1 stop4h 04m
United Airlines
Fri 4/106:00 am
CHS
-
AVP
1 stop3h 48m
United Airlines
Deal found 1/28$269
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:33 pm
AVP
-
CLT
Nonstop1h 59m
American Airlines
Wed 4/810:30 pm
CLT
-
AVP
Nonstop1h 57m
American Airlines
Deal found 1/27$281
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:17 pm
AVP
-
MYR
2 stops35h 41m
Multiple Airlines
Wed 5/279:45 am
MYR
-
AVP
Nonstop1h 48m
Multiple Airlines
Deal found 1/27$283
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:40 pm
AVP
-
SAV
1 stop6h 19m
American Airlines
Wed 4/16:03 pm
SAV
-
AVP
1 stop5h 49m
American Airlines
Deal found 1/27$288
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:40 pm
AVP
-
CHS
1 stop6h 15m
American Airlines
Wed 4/16:34 am
CHS
-
AVP
1 stop5h 29m
American Airlines
Deal found 1/27$296
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:40 pm
AVP
-
CLT
Nonstop2h 00m
American Airlines
Sun 3/1510:00 pm
CLT
-
AVP
Nonstop1h 52m
American Airlines
Deal found 1/28$305
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:17 pm
AVP
-
MYR
1 stop11h 48m
Breeze Airways
Wed 5/279:45 am
MYR
-
AVP
Nonstop1h 48m
Breeze Airways
Deal found 1/27$310
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:40 pm
AVP
-
MYR
1 stop6h 15m
American Airlines
Tue 3/317:10 pm
MYR
-
AVP
1 stop4h 47m
American Airlines
Deal found 1/28$313

Find flight deals from Wilkes-Barre to South Carolina

Keep the following information in mind while searching for Wilkes-Barre to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$188
(Super.com)

One-way from

$124
(Kiwi.com)

Popular in

April

Cheapest in

June

Average price

$457
Provider with most accurate pricing for Wilkes-Barre Scranton-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Myrtle Beach Intl flights.
Search Deals
From Wilkes-Barre to South Carolina
Search Deals
One-way flight from Wilkes-Barre to South Carolina
Search Deals
Highest demand for flights based on searches. 38% potential increase in price ($190 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 15% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to South Carolina that are best for you.

Fly from

Wilkes-Barre

Fly to

South Carolina

Route

Depart

Return

Price

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Sat 4/4

5:40 pm-11:55 pm

1 stop6h 15m

Charleston

Wed 4/8

6:20 pm-12:27 am

1 stop6h 07m

$261

ScrantonGreenville

AVP - GSP

AVPGSP

Wilkes-Barre Scranton

Sat 4/11

6:00 am-9:58 am

1 stop3h 58m

Greenville

Sat 4/18

7:42 pm-11:44 pm

1 stop4h 02m

$269

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Fri 4/3

7:55 pm-11:59 pm

1 stop4h 04m

Charleston

Fri 4/10

6:00 am-9:48 am

1 stop3h 48m

$269

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Sat 3/28

5:40 pm-11:59 pm

1 stop6h 19m

Savannah/Hilton Head

Wed 4/1

6:03 pm-11:52 pm

1 stop5h 49m

$288

ScrantonCharleston

AVP - CHS

AVPCHS

Wilkes-Barre Scranton

Sat 3/28

5:40 pm-11:55 pm

1 stop6h 15m

Charleston

Wed 4/1

6:34 am-12:03 pm

1 stop5h 29m

$296

ScrantonMyrtle Beach

AVP - MYR

AVPMYR

Wilkes-Barre Scranton

Wed 5/6

12:13 pm-2:02 pm

Nonstop1h 49m

Myrtle Beach Intl

Sat 5/9

3:17 pm-8:52 am

2 stops17h 35m

$320

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Wed 2/25

2:12 pm-7:55 pm

1 stop5h 43m

Savannah/Hilton Head

Wed 3/4

9:40 am-4:52 pm

1 stop7h 12m

$329

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Thu 4/9

7:55 pm-11:59 pm

1 stop4h 04m

Savannah/Hilton Head

Tue 4/14

5:45 am-9:48 am

1 stop4h 03m

$332

ScrantonSavannah

AVP - SAV

AVPSAV

Wilkes-Barre Scranton

Fri 3/6

5:40 pm-11:57 pm

1 stop6h 17m

Savannah/Hilton Head

Wed 3/11

6:03 pm-11:52 pm

1 stop5h 49m

$335

ScrantonCharlotte

AVP - CLT

AVPCLT

Wilkes-Barre Scranton

Sat 3/28

5:40 pm-7:40 pm

Nonstop2h 00m

Charlotte Douglas

Mon 3/30

10:12 am-12:03 pm

Nonstop1h 51m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 53 results
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Best time to book a flight from Wilkes-Barre to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to South Carolina

What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to SC?

Find hourly flight availability from Wilkes-Barre to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

One of the essential ways to save on airfare from Wilkes-Barre to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 17% on airfare.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
See what other customers who have flown with Breeze Airways, United Airlines, and American Airlines from Wilkes-Barre to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.2
Very good
263 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
United Airlines
7.4
Good
9,215 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.2
Good
11,206 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilkes-Barre to South Carolina?

    Departing from Wilkes-Barre to South Carolina will take you 3h 58m. The distance from Wilkes-Barre to South Carolina is about 567 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Wilkes-Barre to South Carolina?

    Most travelers choose Wilkes-Barre Scranton - Charlotte Douglas, Wilkes-Barre Scranton - Myrtle Beach Intl or Wilkes-Barre Scranton - Charleston when deciding on the best route from Wilkes-Barre to South Carolina.

  • Can I find deals for flights from Wilkes-Barre to South Carolina that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to South Carolina.

  • Can I find deals for business class flights from Wilkes-Barre to South Carolina?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to South Carolina?

    Currently, November is the cheapest month in which you can book a flight from Wilkes-Barre to South Carolina (average of $83). Flying from Wilkes-Barre to South Carolina in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Wilkes-Barre to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Wilkes-Barre to South Carolina

Discover the top 5 airlines that operate flights from Wilkes-Barre to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$95Average$158FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$100Average$145FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$178Average$453FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$463FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$223Average$372FlexibilityNo cancel feeOn-time69%

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