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$329+ Cheap flights from Waterloo, IA (ALO) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
ALO — CHS
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Cheap flight deals from Waterloo to South Carolina

Keep the following information in mind while searching for Waterloo to South Carolina flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$329
(American Airlines)
Provider with most accurate pricing for Waterloo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Waterloo-Myrtle Beach Intl flights.
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From Waterloo to South Carolina
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Find flight deals from Waterloo to South Carolina

Cheapest flights from Waterloo to South Carolina
Explore the most affordable flight options available from Waterloo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:17 pmALO - GSP
1 stop5h 47mAmerican Airlines
Sat 11/228:14 pmGSP - ALO
1 stop4h 34mAmerican Airlines
Deal found 11/17$379
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amALO - CLT
1 stop4h 29mAmerican Airlines
Wed 12/174:45 pmCLT - ALO
1 stop4h 19mAmerican Airlines
Deal found 11/16$526
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amALO - CLT
1 stop4h 29mAmerican Airlines
Wed 12/179:35 amCLT - ALO
1 stop6h 21mAmerican Airlines
Deal found 11/16$534
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amALO - CLT
2 stops8h 16mAmerican Airlines
Tue 12/1612:56 pmCLT - ALO
2 stops8h 08mAmerican Airlines
Deal found 11/16$544
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amALO - CLT
1 stop4h 29mAmerican Airlines
Sat 12/1311:18 amCLT - ALO
1 stop4h 38mAmerican Airlines
Deal found 11/16$553
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amALO - CLT
1 stop4h 29mAmerican Airlines
Sun 12/146:04 pmCLT - ALO
1 stop6h 47mAmerican Airlines
Deal found 11/16$561
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amALO - CLT
1 stop4h 29mAmerican Airlines
Mon 12/151:09 pmCLT - ALO
2 stops11h 42mAmerican Airlines
Deal found 11/16$566
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:27 pmALO - CLT
1 stop4h 08mAmerican Airlines
Sun 12/149:35 amCLT - ALO
1 stop6h 21mAmerican Airlines
Deal found 11/16$569

Cheapflights Fare Finder

 
Customize your flight search to find flights from Waterloo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Waterloo to South Carolina that are best for you.

Fly from

Waterloo

Fly to

South Carolina

Route

Depart

Return

Price

WaterlooGreenville

ALO - GSP

ALOGSP

Waterloo

Tue 2/3

6:00 am-6:26 pm

2 stops11h 26m

Greenville

Sat 2/7

1:45 pm-10:23 pm

2 stops9h 38m

$329

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Tue 12/9

6:00 am-11:29 am

1 stop4h 29m

Charlotte Douglas

Wed 12/17

1:48 pm-8:04 pm

1 stop7h 16m

$526

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Wed 12/10

3:27 pm-9:49 pm

1 stop5h 22m

Charlotte Douglas

Wed 12/17

11:18 am-2:56 pm

1 stop4h 38m

$526

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Sat 12/13

6:00 am-11:29 am

1 stop4h 29m

Charlotte Douglas

Wed 12/17

4:45 pm-8:04 pm

1 stop4h 19m

$526

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Sat 12/13

6:00 am-11:29 am

1 stop4h 29m

Charlotte Douglas

Tue 12/16

12:56 pm-8:04 pm

2 stops8h 08m

$531

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Thu 12/11

3:27 pm-9:49 pm

1 stop5h 22m

Charlotte Douglas

Tue 12/16

4:45 pm-8:04 pm

1 stop4h 19m

$534

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Wed 12/10

6:00 am-5:21 pm

2 stops10h 21m

Charlotte Douglas

Tue 12/16

12:56 pm-8:04 pm

2 stops8h 08m

$536

WaterlooCharlotte

ALO - CLT

ALOCLT

Waterloo

Wed 12/10

3:27 pm-8:41 pm

1 stop4h 14m

Charlotte Douglas

Sat 12/13

6:04 pm-11:51 pm

1 stop6h 47m

$553

WaterlooMyrtle Beach

ALO - MYR

ALOMYR

Waterloo

Tue 1/27

6:00 am-5:04 pm

2 stops10h 04m

Myrtle Beach Intl

Sat 1/31

3:25 pm-10:23 pm

2 stops7h 58m

$587

WaterlooFlorence

ALO - FLO

ALOFLO

Waterloo

Fri 1/9

6:00 am-5:09 pm

2 stops10h 09m

Florence

Sat 1/10

6:15 am-10:23 pm

2 stops17h 08m

$873

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Best time to book a flight from Waterloo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Waterloo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Waterloo to South Carolina

What is the cheapest month to book a flight from Waterloo, Iowa to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Waterloo, Iowa to South Carolina (average of $166). Flying from Waterloo, Iowa to South Carolina in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Waterloo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Waterloo to South Carolina?

    If you book a flight to South Carolina from Waterloo, you will be flying from Waterloo, which is the city’s only airport. Waterloo (ALO) is located 5.3 mi from the center of Waterloo.

  • How long is the flight from Waterloo, Iowa to South Carolina?

    A quick flight from Waterloo, Iowa to South Carolina can take about 11h 26m. American Airlines provides one of the quickest options available for as low as $329. There are 761 mi between Waterloo, Iowa and South Carolina.

  • What are the most popular routes from Waterloo, Iowa to South Carolina?

    While some choose either Waterloo - Greenville or Waterloo - Florence, Waterloo - Charlotte Douglas is the most popular route from Waterloo, Iowa to South Carolina.

  • Can I find deals for flights from Waterloo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Waterloo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Waterloo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Waterloo to South Carolina.

  • Can I find deals for business class flights from Waterloo to South Carolina?

    Yes. Cheapflights offers flight deals from Waterloo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Waterloo, Iowa to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Waterloo, Iowa to South Carolina (average of $166). Flying from Waterloo, Iowa to South Carolina in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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