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South Carolina

$71+ Cheap flights from Santa Ana, CA (SNA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Santa Ana to South Carolina

Cheapest flights from Santa Ana to South Carolina
Explore the most affordable flight options available from Santa Ana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:02 pm
SNA
-
CLT
2 stops22h 46m
Multiple Airlines
Fri 3/67:43 pm
CLT
-
SNA
1 stop18h 04m
Multiple Airlines
Deal found 1/28$211
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:45 am
SNA
-
CLT
2 stops32h 40m
Multiple Airlines
Thu 3/55:13 pm
CLT
-
SNA
1 stop20h 34m
Multiple Airlines
Deal found 1/28$234
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:25 pm
SNA
-
CLT
2 stops17h 53m
Frontier
Thu 3/55:13 pm
CLT
-
SNA
1 stop20h 34m
Frontier
Deal found 1/28$252
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/128:58 am
SNA
-
CLT
2 stops30h 13m
Multiple Airlines
Thu 3/55:13 pm
CLT
-
SNA
1 stop20h 34m
Multiple Airlines
Deal found 1/28$255
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:20 pm
SNA
-
CLT
2 stops16h 06m
Spirit Airlines
Fri 3/61:24 pm
CLT
-
SNA
2 stops26h 01m
Spirit Airlines
Deal found 1/26$274
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:37 pm
SNA
-
CLT
2 stops23h 11m
Multiple Airlines
Sun 3/87:43 pm
CLT
-
SNA
1 stop18h 04m
Multiple Airlines
Deal found 1/27$280
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:45 am
SNA
-
CLT
2 stops28h 06m
Multiple Airlines
Thu 3/55:13 pm
CLT
-
SNA
1 stop20h 34m
Multiple Airlines
Deal found 1/28$287
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:45 am
SNA
-
CLT
3 stops22h 41m
Spirit Airlines
Thu 3/51:24 pm
CLT
-
SNA
2 stops26h 01m
Spirit Airlines
Deal found 1/28$288
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:37 pm
SNA
-
CLT
2 stops12h 49m
Multiple Airlines
Thu 3/55:13 pm
CLT
-
SNA
1 stop20h 34m
Multiple Airlines
Deal found 1/29$300
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:37 pm
SNA
-
CHS
2 stops15h 14m
Multiple Airlines
Sat 6/138:48 pm
CHS
-
SNA
1 stop20h 56m
Multiple Airlines
Deal found 1/27$362
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:48 pm
SNA
-
MYR
2 stops9h 52m
American Airlines
Thu 3/53:17 pm
MYR
-
SNA
1 stop9h 00m
American Airlines
Deal found 1/27$364
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:50 am
SNA
-
CHS
1 stop7h 35m
United Airlines
Mon 4/202:51 pm
CHS
-
SNA
2 stops10h 07m
United Airlines
Deal found 1/27$376

Find flight deals from Santa Ana to South Carolina

Keep the following information in mind while searching for Santa Ana to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$211
(Kiwi.com)

One-way from

$71
(Expedia)

Popular in

November

Cheapest in

August

Average price

$586
Provider with most accurate pricing for Los Angeles-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Myrtle Beach Intl flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to South Carolina
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to South Carolina
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($116 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Ana to South Carolina that are best for you.

Fly from

Santa Ana

Fly to

South Carolina

Route

Depart

Return

Price

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

11:32 am-6:54 pm

1 stop28h 22m

Charlotte Douglas

Wed 4/29

7:49 pm-10:46 am

1 stop17h 57m

$252

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Sun 3/29

7:45 am-8:21 am

2 stops21h 36m

Charlotte Douglas

Wed 4/1

1:24 pm-8:56 pm

2 stops34h 32m

$341

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Thu 2/12

6:45 am-8:26 am

3 stops22h 41m

Charlotte Douglas

Tue 2/17

7:13 pm-8:57 pm

3 stops28h 44m

$354

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

12:15 pm-9:41 pm

1 stop6h 26m

Charlotte Douglas

Tue 4/7

8:06 am-3:03 pm

1 stop9h 57m

$367

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

6:45 am-5:24 pm

1 stop7h 39m

Charlotte Douglas

Tue 4/28

4:45 pm-9:45 pm

1 stop8h 00m

$367

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Wed 4/15

10:50 am-9:25 pm

1 stop7h 35m

Charleston

Mon 4/20

2:51 pm-9:58 pm

2 stops10h 07m

$376

Santa AnaMyrtle Beach

SNA - MYR

SNAMYR

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

9:20 pm-12:05 pm

2 stops11h 45m

Myrtle Beach Intl

Wed 4/15

3:57 pm-8:57 pm

1 stop8h 00m

$379

Santa AnaAugusta

SNA - AGS

SNAAGS

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

10:55 am-10:19 pm

1 stop8h 24m

Augusta Bush Field

Wed 3/4

3:25 pm-9:18 pm

1 stop8h 53m

$379

Santa AnaAugusta

SNA - AGS

SNAAGS

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

1:23 pm-10:54 pm

1 stop6h 31m

Augusta Bush Field

Sat 5/2

4:15 pm-9:14 pm

1 stop7h 59m

$379

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

6:45 am-9:15 pm

2 stops11h 30m

Charlotte Douglas

Tue 3/31

8:06 am-3:03 pm

1 stop9h 57m

$382

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 60 results
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Best time to book a flight from Santa Ana to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South Carolina

What is the cheapest month to book a flight from Santa Ana, California to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to South Carolina (average of $112). Flying from Santa Ana, California to South Carolina in February is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to SC?

Find hourly flight availability from Santa Ana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

When flying from Santa Ana, California to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 56% versus a flight at noon.

What is the cheapest day to fly from Santa Ana, California to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Santa Ana to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Santa Ana, California to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Santa Ana to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Ana to South Carolina?

    Santa Ana J. Wayne/Orange Cnty (SNA), located 4.8 mi from the city center, is the airport you fly out of when you book flights from Santa Ana to South Carolina.

  • How long is the flight from Santa Ana, California to South Carolina?

    Airlines like Frontier, Spirit Airlines, and United Airlines fly from Santa Ana, California to South Carolina in about 6h 26m. The time it takes to get you to your destination can typically vary by up to 21h 56m. The distance between Santa Ana, California and South Carolina is about 2093 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Santa Ana, California to South Carolina one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $145. Users have also found prices from $156 and $165 on Alaska Airlines and United Airlines, respectively.

  • What are the most popular routes from Santa Ana, California to South Carolina?

    The most popular flight routes from Santa Ana, California to South Carolina are Santa Ana J. Wayne/Orange Cnty - Charlotte Douglas, Santa Ana J. Wayne/Orange Cnty - Charleston and Santa Ana J. Wayne/Orange Cnty - Savannah/Hilton Head.

  • Can I find deals for flights from Santa Ana to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santa Ana to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South Carolina.

  • Can I find deals for business class flights from Santa Ana to South Carolina?

    Yes. Cheapflights offers flight deals from Santa Ana to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to South Carolina (average of $112). Flying from Santa Ana, California to South Carolina in February is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santa Ana to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Santa Ana to South Carolina

Discover the top 4 airlines that operate flights from Santa Ana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$300Average$513FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$300Average$487FlexibilityNo cancel feeOn-time71%
DeltaCheapest$313Average$475FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$388Average$486FlexibilityNo cancel feeOn-time63%

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