HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$85+ Cheap flights from Santa Ana, CA (SNA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — CHS
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Ana to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Santa Ana to South Carolina

Cheapest flights from Santa Ana to South Carolina
Explore the most affordable flight options available from Santa Ana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:01 pmSNA - CLT
1 stop26h 16mFrontier
Thu 11/136:07 pmCLT - SNA
1 stop20h 09mFrontier
Deal found 10/31$222
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:15 amSNA - CLT
1 stop26h 34mFrontier
Sun 12/75:44 pmCLT - SNA
1 stop21h 58mFrontier
Deal found 11/1$226
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:01 pmSNA - CLT
1 stop26h 16mFrontier
Mon 11/106:07 pmCLT - SNA
1 stop22h 23mFrontier
Deal found 11/1$252
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:19 pmSNA - CLT
2 stops10h 20mSpirit Airlines
Mon 12/158:55 amCLT - SNA
2 stops16h 28mSpirit Airlines
Deal found 11/1$285
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:19 pmSNA - CLT
2 stops14h 44mSpirit Airlines
Mon 12/82:58 pmCLT - SNA
2 stops10h 25mSpirit Airlines
Deal found 11/1$288
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:20 pmSNA - CLT
1 stop23h 57mMultiple Airlines
Wed 11/197:54 pmCLT - SNA
2 stops29h 19mMultiple Airlines
Deal found 10/30$296
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:46 pmSNA - CLT
2 stops20h 04mSpirit Airlines
Mon 12/152:58 pmCLT - SNA
2 stops10h 25mSpirit Airlines
Deal found 10/31$311
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2012:04 pmSNA - CLT
1 stop25h 19mFrontier
Sat 11/225:08 pmCLT - SNA
1 stop21h 11mFrontier
Deal found 10/31$339
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:19 pmSNA - CLT
3 stops24h 40mSpirit Airlines
Sun 12/78:55 pmCLT - SNA
3 stops28h 28mSpirit Airlines
Deal found 11/1$343
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:19 pmSNA - MYR
3 stops18h 29mSpirit Airlines
Tue 12/96:59 pmMYR - SNA
3 stops30h 24mSpirit Airlines
Deal found 11/1$369
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:45 pmSNA - CHS
1 stop6h 03mDelta
Sat 1/246:30 amCHS - SNA
1 stop8h 19mDelta
Deal found 11/2$372
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:45 amSNA - MYR
1 stop7h 16mDelta
Tue 12/911:29 amMYR - SNA
2 stops13h 52mDelta
Deal found 11/1$377

Cheap flight deals from Santa Ana to South Carolina

Keep the following information in mind while searching for Santa Ana to South Carolina flight deals. Data was last updated November 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$226
(CheapOair)

One-way from

$85
(Kiwi.com)

Popular in

October

Cheapest in

August

Average price

$638
Provider with most accurate pricing for Los Angeles-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Myrtle Beach Intl flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to South Carolina
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to South Carolina
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Santa Ana to South Carolina that are best for you.

Fly from

Santa Ana

Fly to

South Carolina

Route

Depart

Return

Price

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Sat 11/15

2:20 pm-5:17 pm

1 stop23h 57m

Charlotte Douglas

Wed 11/19

7:54 pm-10:13 pm

2 stops29h 19m

$296

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 1/7

10:51 am-9:58 pm

1 stop8h 07m

Columbia Metropolitan

Mon 1/12

8:00 am-5:28 pm

2 stops12h 28m

$314

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

12:33 pm-6:22 pm

1 stop26h 49m

Charleston

Wed 1/21

7:22 pm-10:05 am

1 stop17h 43m

$347

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

7:25 am-11:44 pm

2 stops13h 19m

Charleston

Wed 1/21

11:00 am-5:22 pm

1 stop9h 22m

$353

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Tue 1/27

10:51 am-9:17 pm

1 stop7h 26m

Charleston

Fri 1/30

4:01 pm-9:18 pm

1 stop8h 17m

$363

Santa AnaMyrtle Beach

SNA - MYR

SNAMYR

Santa Ana J. Wayne/Orange Cnty

Sun 12/7

8:19 pm-5:48 pm

3 stops18h 29m

Myrtle Beach Intl

Tue 12/9

6:59 pm-10:23 pm

3 stops30h 24m

$369

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Mon 12/15

6:45 am-5:24 pm

1 stop7h 39m

Charleston

Sat 1/24

3:00 pm-8:32 pm

1 stop8h 32m

$372

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

6:45 am-6:30 pm

2 stops8h 45m

Charlotte Douglas

Sat 2/7

11:10 am-8:15 pm

1 stop12h 05m

$376

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Fri 12/5

10:41 am-10:12 pm

1 stop8h 31m

Charleston

Sun 12/7

7:00 am-1:57 pm

1 stop9h 57m

$377

Santa AnaMyrtle Beach

SNA - MYR

SNAMYR

Santa Ana J. Wayne/Orange Cnty

Sun 12/7

12:45 pm-11:43 pm

1 stop7h 58m

Myrtle Beach Intl

Wed 12/10

11:29 am-10:30 pm

2 stops14h 01m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Santa Ana to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South Carolina

What is the cheapest month to book a flight from Santa Ana, California to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to South Carolina (average of $117). Flying from Santa Ana, California to South Carolina in January is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to SC?

Find hourly flight availability from Santa Ana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

When flying from Santa Ana, California to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 31% versus a flight in the morning.

What is the cheapest day to fly from Santa Ana, California to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Santa Ana to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Santa Ana, California to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 2, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Santa Ana to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,240 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,997 reviews
Southwest
8.0
Very good
4,240 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,034 reviews
Southwest
8.0
Very good
4,240 reviews

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Ana to South Carolina?

    Santa Ana J. Wayne/Orange Cnty (SNA), located 4.8 mi from the city center, is the airport you fly out of when you book flights from Santa Ana to South Carolina.

  • How long is the flight from Santa Ana, California to South Carolina?

    Airlines like United Airlines, Alaska Airlines, and Spirit Airlines fly from Santa Ana, California to South Carolina in about 8h 07m. The time it takes to get you to your destination can typically vary by up to 18h 42m. The distance between Santa Ana, California and South Carolina is about 2096 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Santa Ana, California to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $117. Users have also found prices from $118 and $180 on Spirit Airlines and Delta, respectively.

  • What are the most popular routes from Santa Ana, California to South Carolina?

    The most popular flight routes from Santa Ana, California to South Carolina are Santa Ana J. Wayne/Orange Cnty - Charlotte Douglas, Santa Ana J. Wayne/Orange Cnty - Charleston and Santa Ana J. Wayne/Orange Cnty - Savannah/Hilton Head.

  • Can I find deals for flights from Santa Ana to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santa Ana to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South Carolina.

  • Can I find deals for business class flights from Santa Ana to South Carolina?

    Yes. Cheapflights offers flight deals from Santa Ana to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to South Carolina (average of $117). Flying from Santa Ana, California to South Carolina in January is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Los Angeles to Newark flights
San Francisco to Los Angeles flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to San Francisco flights
Los Angeles to LaGuardia flights
Los Angeles to Honolulu flights
Los Angeles to Seattle flights
San Francisco to Newark flights
San Francisco to Ontario flights
San Francisco to Las Vegas flights
Ontario to San Francisco flights
San Francisco to Dallas/Fort Worth flights
San Francisco to Honolulu flights
San Francisco to Santa Ana flights
Ontario to Dallas/Fort Worth flights
Los Angeles to Las Vegas flights
San Francisco to LaGuardia flights
Los Angeles to Orlando flights
San Francisco to Seattle flights
Los Angeles to Miami flights
San Francisco to O'Hare Intl flights
Burbank to Las Vegas flights
Los Angeles to O'Hare Intl flights
Los Angeles to Fort Lauderdale flights
San Jose to Los Angeles flights
San Diego to John F Kennedy Intl flights
Los Angeles to Boston flights
Los Angeles to Reagan-National flights
Santa Ana to San Francisco flights
Los Angeles to Portland flights
San Jose to Las Vegas flights
Los Angeles to Denver flights
Los Angeles to Sky Harbor Intl flights
Los Angeles to Dulles Intl flights
Santa Ana to Dallas/Fort Worth flights
Santa Ana to Seattle flights
San Francisco to Kahului flights
Santa Ana to Las Vegas flights
San Diego to Seattle flights
Ontario to John F Kennedy Intl flights
Los Angeles to Baltimore flights
Los Angeles to Kahului flights
Ontario to Seattle flights
Los Angeles to Hobby flights
Los Angeles to San Jose flights
San Francisco to Orlando flights
Burbank to LaGuardia flights
Sacramento to Los Angeles flights

Top 4 airlines flying from Santa Ana to South Carolina

Discover the top 4 airlines that operate flights from Santa Ana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$300Average$538FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$300Average$485FlexibilityNo cancel feeOn-time71%
DeltaCheapest$328Average$466FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$388Average$466FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.