HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$97+ Cheap flights from Portland, ME (PWM) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This Super.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:05 pmPWM - CHS
Nonstop2h 38mBreeze Airways
Mon 12/223:04 pmCHS - PWM
Nonstop2h 21mBreeze Airways
Deal found 12/14$337
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:05 pmPWM - CHS
Nonstop2h 38mBreeze Airways
Thu 1/17:00 amCHS - PWM
2 stops27h 41mBreeze Airways
Deal found 12/14$342
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:45 amPWM - MYR
1 stop6h 46mDelta
Wed 12/315:12 pmMYR - PWM
1 stop5h 31mDelta
Deal found 12/13$347
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:05 pmPWM - CHS
Nonstop2h 38mMultiple Airlines
Mon 12/2210:18 pmCHS - PWM
2 stops36h 18mMultiple Airlines
Deal found 12/14$370
This Delta deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:45 amPWM - CLT
1 stop8h 01mDelta
Wed 12/314:51 pmCLT - PWM
1 stop5h 52mDelta
Deal found 12/12$372
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:17 amPWM - CLT
Nonstop2h 46mAmerican Airlines
Tue 12/306:18 pmCLT - PWM
1 stop4h 37mAmerican Airlines
Deal found 12/13$387
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:30 amPWM - CLT
1 stop4h 45mSouthwest
Fri 12/198:05 pmCLT - PWM
1 stop4h 00mSouthwest
Deal found 12/13$397
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:34 amPWM - CLT
1 stop4h 20mAmerican Airlines
Mon 12/157:24 pmCLT - PWM
Nonstop2h 13mAmerican Airlines
Deal found 12/11$413
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:55 pmPWM - CLT
1 stop7h 04mUnited Airlines
Sat 1/37:44 pmCLT - PWM
1 stop4h 15mUnited Airlines
Deal found 12/12$416
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:19 amPWM - CLT
2 stops11h 01mUnited Airlines
Wed 12/317:44 pmCLT - PWM
1 stop4h 15mUnited Airlines
Deal found 12/13$421
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:17 amPWM - CLT
Nonstop2h 46mAmerican Airlines
Sun 12/218:33 pmCLT - PWM
Nonstop2h 18mAmerican Airlines
Deal found 12/13$422
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:53 pmPWM - CLT
1 stop5h 02mDelta
Mon 12/159:59 amCLT - PWM
1 stop6h 04mDelta
Deal found 12/11$423

Find flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated December 14, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$97
(Super.com)

One-way from

$49
(Super.com)

Popular in

April

Cheapest in

January

Average price

$179

Good round-trip deal

$150 or less

Good one-way deal

$59 or less
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
Search Deals
From Portland to South Carolina
Search Deals
One-way flight from Portland to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Portland to South Carolina.
Search Deals
Price to beat on a one-way flight from Portland to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Mon 1/26

5:06 pm-7:48 pm

Nonstop2h 42m

Charleston

Fri 1/30

2:02 pm-4:26 pm

Nonstop2h 24m

$97

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 1/16

5:06 pm-7:48 pm

Nonstop2h 42m

Charleston

Mon 1/19

2:02 pm-4:26 pm

Nonstop2h 24m

$133

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 1/30

11:29 am-5:36 pm

2 stops30h 07m

Charleston

Mon 2/2

2:02 pm-4:26 pm

Nonstop2h 24m

$247

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Sun 1/18

7:15 am-12:45 pm

1 stop5h 30m

Myrtle Beach Intl

Sat 1/24

4:00 pm-10:27 pm

1 stop6h 27m

$256

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 2/27

5:31 am-10:15 am

1 stop4h 44m

Charleston

Wed 3/4

5:38 pm-11:51 pm

2 stops6h 13m

$259

PortlandCharlotte

PWM - CLT

PWMCLT

Portland

Fri 1/9

5:06 pm-12:40 am

2 stops31h 34m

Charlotte Douglas

Tue 1/13

6:01 pm-10:22 am

1 stop16h 21m

$259

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Tue 1/27

6:00 am-11:41 am

1 stop5h 41m

Myrtle Beach Intl

Sat 1/31

12:35 pm-7:38 pm

1 stop7h 03m

$277

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Sat 1/31

6:00 am-11:54 am

1 stop5h 54m

Myrtle Beach Intl

Tue 2/3

4:00 pm-10:27 pm

1 stop6h 27m

$277

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Sat 2/21

5:31 am-11:49 am

1 stop6h 18m

Myrtle Beach Intl

Tue 2/24

6:52 am-6:03 pm

2 stops11h 11m

$282

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Tue 1/27

2:35 pm-11:41 pm

2 stops9h 06m

Myrtle Beach Intl

Tue 2/3

4:00 pm-10:27 pm

1 stop6h 27m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $58). Flying from Portland, Maine to South Carolina in June is currently the most expensive (average of $77). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

One of the essential ways to save on airfare from Portland, Maine to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 57% on airfare.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 14, 2025.
Read reviews from past customers who have flown Breeze Airways, Southwest, and Delta from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
248 reviews

Overall

8.2

Comfort

8.2

Entertainment

6.7

Food

6.7

Boarding

8.4

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Breeze Airways
8.2
Very good
248 reviews
Breeze Airways
8.2
Very good
248 reviews

Overall

8.2

Comfort

8.2

Entertainment

6.7

Food

6.7

Boarding

8.4

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Southwest
7.9
Good
4,250 reviews
Breeze Airways
8.2
Very good
248 reviews

Overall

8.2

Comfort

8.2

Entertainment

6.7

Food

6.7

Boarding

8.4

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Delta
7.9
Good
8,007 reviews
Breeze Airways
8.2
Very good
248 reviews

Overall

8.2

Comfort

8.2

Entertainment

6.7

Food

6.7

Boarding

8.4

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
United Airlines
7.4
Good
9,094 reviews
Breeze Airways
8.2
Very good
248 reviews

Overall

8.2

Comfort

8.2

Entertainment

6.7

Food

6.7

Boarding

8.4

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
American Airlines
7.2
Good
11,054 reviews
Breeze Airways
8.2
Very good
248 reviews

Overall

8.2

Comfort

8.2

Entertainment

6.7

Food

6.7

Boarding

8.4

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PWM), located 2.9 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How popular is this Portland, Maine to South Carolina flight route?

    Flights from Portland to South Carolina have been viewed 6 times in the past calendar month.

  • How long is the flight from Portland, Maine to South Carolina?

    For as low as $97, Breeze Airways can have you in South Carolina from Portland, Maine in 2h 42m. There are 909 mi between Portland, Maine and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?

    One-way options have recently been found by users for as low as $46 on Breeze Airways. Other airlines that offer cheap prices include Southwest from $97 and American Airlines from $118 one-way.

  • What are the most popular routes from Portland, Maine to South Carolina?

    When deciding which route to take from Portland, Maine to South Carolina consider Portland - Charlotte Douglas, Portland - Charleston or Portland - Savannah/Hilton Head as they are the most popular.

  • What are the cheapest flights from Portland, Maine to South Carolina?

    Looking for the cheapest flight from Portland, Maine to South Carolina? While on average our users pay $298, our data indicates the cheapest price to be $56. The most popular route (Portland - Charlotte Douglas), is priced around $268.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $58). Flying from Portland, Maine to South Carolina in June is currently the most expensive (average of $77). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Fort Lauderdale flights
Boston to Miami flights
Boston to Tampa flights
Boston to Orlando flights
Boston to Las Vegas flights
Boston to Los Angeles flights
Boston to Dallas/Fort Worth flights
Boston to Fort Myers flights
Boston to Denver flights
Boston to San Francisco flights
Boston to Sky Harbor Intl flights
Boston to West Palm Beach flights
Boston to New Orleans flights
Boston to Hobby flights
Boston to Atlanta flights
Boston to Salt Lake City flights
Boston to Baltimore flights
Boston to Seattle flights
Boston to Sarasota flights
Boston to George Bush Intcntl flights
Boston to O'Hare Intl flights
Boston to Dulles Intl flights
Boston to Reagan-National flights
Boston to Nashville flights
Boston to LaGuardia flights
Boston to Austin flights
Boston to San Diego flights
Boston to Charlotte flights
Boston to Philadelphia flights
Boston to Raleigh flights
Boston to Charleston flights
Boston to John F Kennedy Intl flights
Boston to Newark flights
Boston to Honolulu flights
Boston to Jacksonville flights
Boston to Key West flights
Boston to Savannah flights
Boston to Ontario flights
Boston to Midway flights
Boston to Detroit flights
Boston to Columbus flights
Boston to Minneapolis flights
Boston to Love Field flights
Boston to Cleveland flights
Boston to Bozeman flights
Portland to Orlando flights
Boston to Portland flights
Boston to Pittsburgh flights
Boston to Santa Ana flights
Boston to Daytona Beach flights

Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$173FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$148Average$353FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$236Average$432FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$236Average$389FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$296Average$386FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.