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South Carolina

$49+ Cheap flights from Portland, ME (PWM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated July 29, 2025.

Round-trip from

$99
(Breeze Airways)

One-way from

$49
(Breeze Airways)

Popular in

April

Cheapest in

August

Average price

$436

Good round-trip deal

$218 or less

Good one-way deal

$94 or less
From Portland to South Carolina
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One-way flight from Portland to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Portland to South Carolina.
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Price to beat on a one-way flight from Portland to South Carolina.
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Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Breeze Airways deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:05 pmPWM - CHS
Nonstop2h 38mBreeze Airways
Mon 9/223:04 pmCHS - PWM
Nonstop2h 21mBreeze Airways
Deal found 7/27$99
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:15 pmPWM - GSP
1 stop4h 08mBreeze Airways
Sun 9/1410:33 amGSP - PWM
1 stop3h 57mBreeze Airways
Deal found 7/29$150
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/96:58 pmPWM - CLT
1 stop16h 44mFrontier
Fri 8/159:17 pmCLT - PWM
1 stop20h 56mFrontier
Deal found 7/29$215
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:30 amPWM - SAV
1 stop10h 18mDelta
Sat 10/1812:10 pmSAV - PWM
1 stop11h 55mDelta
Deal found 7/28$233
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:44 amPWM - MYR
1 stop6h 27mAmerican Airlines
Sat 10/259:57 amMYR - PWM
1 stop7h 12mAmerican Airlines
Deal found 7/27$237
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:00 amPWM - CHS
1 stop7h 50mDelta
Wed 8/277:00 amCHS - PWM
1 stop6h 56mDelta
Deal found 7/28$237
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:12 pmPWM - SAV
1 stop4h 24mAmerican Airlines
Sat 10/255:00 amSAV - PWM
2 stops6h 54mAmerican Airlines
Deal found 7/29$242
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:00 amPWM - GSP
2 stops9h 23mDelta
Sun 9/146:00 amGSP - PWM
1 stop7h 00mDelta
Deal found 7/29$242
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/207:09 amPWM - CHS
2 stops6h 59mAmerican Airlines
Wed 8/273:54 pmCHS - PWM
1 stop4h 42mAmerican Airlines
Deal found 7/28$242
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:21 pmPWM - CAE
1 stop6h 22mAmerican Airlines
Tue 11/46:13 pmCAE - PWM
1 stop4h 34mAmerican Airlines
Deal found 7/29$249
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/161:40 pmPWM - MYR
2 stops10h 09mDelta
Mon 9/226:55 pmMYR - PWM
1 stop5h 16mDelta
Deal found 7/28$252
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2910:00 amPWM - CAE
2 stops9h 02mDelta
Tue 11/42:58 pmCAE - PWM
2 stops8h 09mDelta
Deal found 7/29$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 9/19

6:05 pm-8:43 pm

Nonstop2h 38m

Charleston

Mon 9/22

3:04 pm-5:25 pm

Nonstop2h 21m

$99

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 9/11

3:15 pm-7:23 pm

1 stop4h 08m

Greenville

Sun 9/14

10:33 am-2:30 pm

1 stop3h 57m

$150

PortlandCharlotte

PWM - CLT

PWMCLT

Portland

Sat 8/9

6:58 pm-11:42 am

1 stop16h 44m

Charlotte Douglas

Fri 8/15

9:17 pm-6:13 pm

1 stop20h 56m

$215

PortlandSavannah

PWM - SAV

PWMSAV

Portland

Sat 10/11

6:30 am-4:48 pm

1 stop10h 18m

Savannah/Hilton Head

Wed 10/22

12:10 pm-12:05 am

1 stop11h 55m

$233

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Tue 10/21

7:44 am-2:11 pm

1 stop6h 27m

Myrtle Beach Intl

Sat 10/25

9:57 am-5:09 pm

1 stop7h 12m

$237

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 8/20

6:00 am-1:50 pm

1 stop7h 50m

Charleston

Wed 8/27

7:00 am-1:56 pm

1 stop6h 56m

$237

PortlandSavannah

PWM - SAV

PWMSAV

Portland

Sat 10/18

6:00 am-10:10 am

1 stop4h 10m

Savannah/Hilton Head

Sat 10/25

5:00 am-11:54 am

2 stops6h 54m

$242

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 9/11

6:00 am-3:23 pm

2 stops9h 23m

Greenville

Sun 9/14

6:00 am-1:00 pm

1 stop7h 00m

$242

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 8/20

7:09 am-2:08 pm

2 stops6h 59m

Charleston

Wed 8/27

3:54 pm-8:36 pm

1 stop4h 42m

$242

PortlandColumbia

PWM - CAE

PWMCAE

Portland

Sat 10/4

7:00 am-1:42 pm

1 stop6h 42m

Columbia Metropolitan

Tue 10/7

5:32 pm-10:19 pm

1 stop4h 47m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 60 results
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Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $217). Flying from Portland, Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from Portland, Maine to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2025.
Read reviews from past customers who have flown Southwest, Delta, and Breeze Airways from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Breeze Airways
8.0
Very good
190 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PWM), located 2.9 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How popular is this Portland, Maine to South Carolina flight route?

    Flights from Portland to South Carolina have been viewed 3 times in the past calendar month.

  • What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?

    One-way options have recently been found by users for as low as $49 on Breeze Airways. Other airlines that offer cheap prices include Frontier from $99 and Southwest from $118 one-way.

  • What are the most popular routes from Portland, Maine to South Carolina?

    When deciding which route to take from Portland, Maine to South Carolina consider Portland - Charlotte Douglas, Portland - Charleston or Portland - Myrtle Beach Intl as they are the most popular.

  • What are the cheapest flights from Portland, Maine to South Carolina?

    Looking for the cheapest flight from Portland, Maine to South Carolina? While on average our users pay $226, our data indicates the cheapest price to be $75. The most popular route (Portland - Charlotte Douglas), is priced around $282.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $217). Flying from Portland, Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$185FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$147Average$348FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$176Average$399FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$188Average$395FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$256Average$426FlexibilityNo cancel feeOn-time63%

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