How popular is this Portland, Maine to South Carolina flight route?

Flights from Portland to South Carolina have been viewed 2 times in the past calendar month.

What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?

One-way options have recently been found by users for as low as $49 on Breeze Airways. Other airlines that offer cheap prices include Frontier from $116 and Delta from $129 one-way.

What are the most popular routes from Portland, Maine to South Carolina?

When deciding which route to take from Portland, Maine to South Carolina consider Portland - Charlotte Douglas, Portland - Myrtle Beach Intl or Portland - Savannah/Hilton Head as they are the most popular.

What are the cheapest flights from Portland, Maine to South Carolina?

Looking for the cheapest flight from Portland, Maine to South Carolina? While on average our users pay $171, our data indicates the cheapest price to be $45. The most popular route (Portland - Charlotte Douglas), is priced around $316.

What are the most popular airlines that fly from Portland, Maine to South Carolina?

When booking a flight from Portland, Maine to South Carolina, you may want to consider flying on American Airlines, Delta or Breeze Airways as they are the most popular for this route.

How far in advance should I book a flight from Portland, Maine to South Carolina?

Travelers have found it’s best to book a flight 32 days in advance to save up to 71% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 32 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Portland, Maine to South Carolina 1-2 weeks in advance for as low as $521, or $526 for flights within the next 24 hours.

What is the cheapest month to fly from Portland, Maine to South Carolina?

December can be a great time to fly to South Carolina from Portland, Maine with a flight ticket averaging about $396. Cheapflights users have found deals in the month of December for as cheap as $296. The most expensive prices can be found in the month of April.

What airport do you fly from for flights from Portland to South Carolina?

Portland (PWM), located 2.9 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

Can I find deals for flights from Portland to South Carolina that include hotel bookings?

Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

Can I find deals for business class flights from Portland to South Carolina?

Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$49+ Flights from Portland, ME to South Carolina - Compare & Save Big

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Cheap flight deals from Portland to South Carolina

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$104 (CheapOair)
One-way from	$49 (Breeze Airways)
Popular in	April
Cheapest in	December
Average price	$466
Good round-trip deal	$124 or less
Good one-way deal	$73 or less

Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.

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Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.

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From Portland to South Carolina

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One-way flight from Portland to South Carolina

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Price to beat on a round-trip flight from Portland to South Carolina.

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Price to beat on a one-way flight from Portland to South Carolina.

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Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Mon 5/56:16 pmPWM - CHS

Nonstop2h 35mBreeze Airways

Wed 5/145:17 pmCHS - PWM

Nonstop2h 23mBreeze Airways

Deal found 4/28

$98

Mon 6/166:00 amPWM - SAV

1 stop7h 39mDelta

Thu 6/196:44 pmSAV - PWM

1 stop4h 46mDelta

Deal found 4/28

$237

Fri 6/65:30 pmPWM - CAE

1 stop5h 26mDelta

Sun 6/84:30 pmCAE - PWM

1 stop7h 00mDelta

Deal found 4/28

$249

Sun 5/257:35 amPWM - HHH

1 stop4h 45mAmerican Airlines

Wed 5/286:20 pmHHH - PWM

1 stop4h 46mAmerican Airlines

Deal found 4/27

$249

Sun 6/296:00 amPWM - MYR

1 stop6h 29mDelta

Wed 7/25:25 pmMYR - PWM

1 stop7h 01mDelta

Deal found 4/28

$257

Sun 6/83:17 pmPWM - GSP

1 stop4h 09mBreeze Airways

Sun 6/1510:34 amGSP - PWM

1 stop3h 58mBreeze Airways

Deal found 4/28

$259

Sat 8/308:00 amPWM - MYR

2 stops9h 15mAmerican Airlines

Sat 9/137:20 amMYR - PWM

2 stops5h 53mAmerican Airlines

Deal found 4/29

$267

Wed 5/215:30 amPWM - CHS

1 stop5h 47mDelta

Sat 5/246:50 pmCHS - PWM

1 stop5h 09mDelta

Deal found 4/29

$271

Tue 6/176:00 amPWM - SAV

2 stops6h 20mAmerican Airlines

Tue 6/246:24 pmSAV - PWM

1 stop4h 39mAmerican Airlines

Deal found 4/29

$276

Wed 5/212:05 pmPWM - CHS

2 stops7h 59mAmerican Airlines

Tue 5/277:24 pmCHS - PWM

1 stop4h 31mAmerican Airlines

Deal found 4/29

$276

Fri 6/65:30 amPWM - AGS

1 stop5h 29mDelta

Sun 6/87:54 pmAGS - PWM

1 stop4h 32mDelta

Deal found 4/28

$277

Thu 5/19:29 pmPWM - CLT

1 stop9h 25mFrontier

Sun 5/410:36 pmCLT - PWM

1 stop22h 04mFrontier

Deal found 4/27

$282

Best flights from Portland to South Carolina
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2025.

Wed 6/118:07 pmPWM - CHS

Nonstop2h 34mBreeze Airways

Wed 6/185:04 pmCHS - PWM

Nonstop2h 23mBreeze Airways

Deal found 4/29

$104

Mon 6/166:00 amPWM - SAV

1 stop7h 39mDelta

Thu 6/196:44 pmSAV - PWM

1 stop4h 46mDelta

Deal found 4/28

$237

Wed 5/2111:07 amPWM - MYR

2 stops6h 32mAmerican Airlines

Wed 5/285:00 amMYR - PWM

2 stops8h 22mAmerican Airlines

Deal found 4/27

$267

Wed 6/412:30 pmPWM - CHS

1 stop5h 50mSouthwest

Mon 6/98:05 pmCHS - PWM

1 stop4h 00mSouthwest

Deal found 4/28

$287

Wed 6/44:04 pmPWM - CHS

2 stops7h 53mUnited Airlines

Mon 6/96:30 amCHS - PWM

1 stop8h 01mUnited Airlines

Deal found 4/28

$292

Thu 5/2912:47 pmPWM - CLT

1 stop27h 54mMultiple Airlines

Mon 6/211:52 amCLT - PWM

3 stops25h 13mMultiple Airlines

Deal found 4/29

$412

Fri 6/65:30 pmPWM - CAE

1 stop5h 26mDelta

Sun 6/87:41 pmCAE - PWM

1 stop4h 45mDelta

Deal found 4/29

$249

Sun 6/83:17 pmPWM - GSP

1 stop4h 09mBreeze Airways

Sun 6/1510:34 amGSP - PWM

1 stop3h 58mBreeze Airways

Deal found 4/28

$259

Tue 6/176:00 amPWM - SAV

2 stops6h 20mAmerican Airlines

Tue 6/246:24 pmSAV - PWM

1 stop4h 39mAmerican Airlines

Deal found 4/29

$276

Sun 6/296:00 amPWM - MYR

1 stop6h 29mDelta

Wed 7/25:25 pmMYR - PWM

1 stop7h 01mDelta

Deal found 4/28

$257

Tue 7/85:50 pmPWM - CLT

1 stop4h 50mSouthwest

Tue 7/156:55 pmCLT - PWM

1 stop4h 30mSouthwest

Deal found 4/29

$297

Wed 5/212:05 pmPWM - CHS

2 stops7h 59mAmerican Airlines

Tue 5/277:24 pmCHS - PWM

1 stop4h 31mAmerican Airlines

Deal found 4/29

$276

Last-minute flights from Portland to South Carolina
Discover last-minute flight deals from Portland to South Carolina. Data last updated April 29, 2025 and is based on user searches.

Wed 4/306:15 amPWM - CLT

1 stop4h 10mSouthwest

Wed 5/71:55 pmCLT - PWM

1 stop8h 35mSouthwest

Deal found 4/29

$308

Fri 5/29:30 pmPWM - CLT

1 stop20h 22mFrontier

Mon 5/59:47 amCLT - PWM

1 stop10h 53mFrontier

Deal found 4/29

$310

Sun 5/45:38 amPWM - HHH

1 stop5h 25mAmerican Airlines

Wed 5/146:20 pmHHH - PWM

1 stop4h 46mAmerican Airlines

Deal found 4/29

$335

Mon 5/56:16 pmPWM - CHS

Nonstop2h 35mBreeze Airways

Wed 5/145:17 pmCHS - PWM

Nonstop2h 23mBreeze Airways

Deal found 4/28

$98

Tue 5/64:40 pmPWM - GSP

1 stop4h 58mDelta

Thu 5/86:00 amGSP - PWM

1 stop6h 57mDelta

Deal found 4/29

$444

Tue 5/63:43 pmPWM - SAV

1 stop8h 16mUnited Airlines

Sat 5/176:30 amSAV - PWM

1 stop7h 25mUnited Airlines

Deal found 4/28

$477

Tue 5/64:01 pmPWM - SAV

2 stops7h 55mAmerican Airlines

Sat 5/175:00 amSAV - PWM

2 stops8h 22mAmerican Airlines

Deal found 4/28

$487

Wed 5/76:15 amPWM - CHS

1 stop7h 00mSouthwest

Mon 5/127:10 pmCHS - PWM

1 stop4h 10mSouthwest

Deal found 4/28

$327

Wed 5/74:05 pmPWM - CLT

1 stop4h 15mSouthwest

Sat 5/107:30 amCLT - PWM

1 stop4h 35mSouthwest

Deal found 4/29

$433

Wed 5/77:45 amPWM - CLT

Nonstop2h 29mAmerican Airlines

Sat 5/1011:05 amCLT - PWM

Nonstop2h 27mAmerican Airlines

Deal found 4/29

$437

Thu 5/86:55 pmPWM - CLT

1 stop5h 03mUnited Airlines

Fri 5/166:00 amCLT - PWM

2 stops7h 56mUnited Airlines

Deal found 4/29

$560

Fri 5/92:30 pmPWM - CHS

1 stop6h 13mDelta

Mon 5/126:24 pmCHS - PWM

1 stop5h 35mDelta

Deal found 4/28

$317

One-way flights from Portland to South Carolina
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 29, 2025.

Wed 5/78:20 pmPWM - CHS

Nonstop2h 34mBreeze Airways

Deal found 4/29

$49

Thu 5/153:17 pmPWM - GSP

1 stop4h 09mBreeze Airways

Deal found 4/28

$92

Thu 5/159:29 pmPWM - CLT

1 stop9h 25mFrontier

Deal found 4/28

$116

Thu 5/296:05 amPWM - MYR

1 stop5h 34mDelta

Deal found 4/29

$129

Thu 5/292:05 pmPWM - MYR

2 stops8h 26mAmerican Airlines

Deal found 4/29

$134

Fri 7/412:55 pmPWM - SAV

1 stop5h 10mDelta

Deal found 4/28

$136

Wed 6/185:08 amPWM - GSP

1 stop5h 34mAmerican Airlines

Deal found 4/29

$136

Sat 7/56:03 amPWM - CHS

1 stop6h 39mDelta

Deal found 4/28

$136

Fri 7/46:00 amPWM - SAV

2 stops8h 23mAmerican Airlines

Deal found 4/28

$141

Tue 6/247:41 amPWM - CHS

2 stops7h 08mAmerican Airlines

Deal found 4/29

$141

Wed 5/284:05 pmPWM - CLT

1 stop4h 15mSouthwest

Deal found 4/27

$152

Sun 5/256:05 amPWM - CLT

1 stop6h 34mDelta

Deal found 4/27

$154

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 6/11

8:07 pm-10:41 pm

Nonstop2h 34m

Charleston

Wed 6/18

5:04 pm-7:27 pm

Nonstop2h 23m

$104

PortlandSavannah

PWM - SAV

PWMSAV

Portland

Mon 6/16

6:00 am-1:39 pm

1 stop7h 39m

Savannah/Hilton Head

Thu 6/19

6:44 pm-11:30 pm

1 stop4h 46m

$237

PortlandColumbia

PWM - CAE

PWMCAE

Portland

Fri 6/6

5:30 pm-10:56 pm

1 stop5h 26m

Columbia Metropolitan

Sun 6/8

7:41 pm-12:26 am

1 stop4h 45m

$249

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Sun 6/29

6:00 am-12:29 pm

1 stop6h 29m

Myrtle Beach Intl

Tue 7/1

5:25 pm-12:26 am

1 stop7h 01m

$257

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Sun 6/8

3:17 pm-7:26 pm

1 stop4h 09m

Greenville

Sun 6/15

10:34 am-2:32 pm

1 stop3h 58m

$259

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Wed 5/21

11:07 am-5:39 pm

2 stops6h 32m

Myrtle Beach Intl

Wed 5/28

5:00 am-1:22 pm

2 stops8h 22m

$267

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 5/21

5:30 am-11:17 am

1 stop5h 47m

Charleston

Sat 5/24

6:50 pm-11:59 pm

1 stop5h 09m

$271

PortlandSavannah

PWM - SAV

PWMSAV

Portland

Tue 6/17

6:00 am-12:20 pm

2 stops6h 20m

Savannah/Hilton Head

Tue 6/24

6:24 pm-11:03 pm

1 stop4h 39m

$276

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 5/21

2:05 pm-10:04 pm

2 stops7h 59m

Charleston

Tue 5/27

7:24 pm-11:55 pm

1 stop4h 31m

$276

PortlandAugusta

PWM - AGS

PWMAGS

Portland

Fri 6/6

5:30 am-10:59 am

1 stop5h 29m

Augusta Bush Field

Sun 6/8

7:54 pm-12:26 am

1 stop4h 32m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 58 results

...

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $217). Flying from Portland, Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to SC?

When flying from Portland, Maine to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

To help decide which airline to fly from Portland to South Carolina, see what other customers have to say about Breeze Airways, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Breeze Airways

8.1

Very good

160 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Breeze Airways

8.1

Very good

160 reviews

Breeze Airways

8.1

Very good

160 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Southwest

8.0

Very good

4,295 reviews

Breeze Airways

8.1

Very good

160 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Delta

8.0

Very good

7,929 reviews

Breeze Airways

8.1

Very good

160 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

United Airlines

7.4

Good

8,696 reviews

Breeze Airways

8.1

Very good

160 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

JetBlue

7.3

Good

2,922 reviews

Breeze Airways

8.1

Very good

160 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

What airport do you fly from for flights from Portland to South Carolina?
Portland (PWM), located 2.9 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.
How popular is this Portland, Maine to South Carolina flight route?
Flights from Portland to South Carolina have been viewed 2 times in the past calendar month.
What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?
One-way options have recently been found by users for as low as $49 on Breeze Airways. Other airlines that offer cheap prices include Frontier from $116 and Delta from $129 one-way.
What are the most popular routes from Portland, Maine to South Carolina?
When deciding which route to take from Portland, Maine to South Carolina consider Portland - Charlotte Douglas, Portland - Myrtle Beach Intl or Portland - Savannah/Hilton Head as they are the most popular.
What are the cheapest flights from Portland, Maine to South Carolina?
Looking for the cheapest flight from Portland, Maine to South Carolina? While on average our users pay $171, our data indicates the cheapest price to be $45. The most popular route (Portland - Charlotte Douglas), is priced around $316.
Can I find deals for flights from Portland to South Carolina that include hotel bookings?
Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.
Can I find deals for business class flights from Portland to South Carolina?
Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland, Maine to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $217). Flying from Portland, Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

South Carolina car rentals

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Top 5 airlines flying from Portland to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
Breeze Airways	Cheapest$90	Average$189	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$180	Average$406	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$188	Average$324	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$188	Average$347	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$236	Average$429	FlexibilityNo cancel fee	On-time63%

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$49+ Cheap flights from Portland, ME (PWM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to South Carolina with Cheapflights

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Cheap flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated April 29, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

What is the cheapest time of day to fly from PWM to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

Reviews of airlines servicing South Carolina

To help decide which airline to fly from Portland to South Carolina, see what other customers have to say about Breeze Airways, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Portland to South Carolina?

How popular is this Portland, Maine to South Carolina flight route?

What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?

What are the most popular routes from Portland, Maine to South Carolina?

What are the cheapest flights from Portland, Maine to South Carolina?

Can I find deals for flights from Portland to South Carolina that include hotel bookings?

How can I find direct flights from Portland to South Carolina?

Can I find deals for business class flights from Portland to South Carolina?

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Portland to South Carolina

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Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.