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South Carolina

$45+ Cheap flights from Portland, ME (PWM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated September 11, 2025.

Round-trip from

$193
(American Airlines)

One-way from

$90
(Southwest)

Popular in

April

Cheapest in

August

Average price

$426

Good round-trip deal

$123 or less

Good one-way deal

$99 or less
From Portland to South Carolina
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One-way flight from Portland to South Carolina
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Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Portland to South Carolina.
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Price to beat on a one-way flight from Portland to South Carolina.
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Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:46 amPWM - MYR
1 stop5h 22mAmerican Airlines
Sat 1/177:57 pmMYR - PWM
1 stop3h 53mAmerican Airlines
Deal found 9/10$193
This Breeze Airways deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:05 pmPWM - CHS
Nonstop2h 38mBreeze Airways
Fri 12/263:04 pmCHS - PWM
Nonstop2h 21mBreeze Airways
Deal found 9/11$194
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/153:15 pmPWM - CHS
1 stop4h 35mSouthwest
Wed 12/35:45 pmCHS - PWM
1 stop4h 30mSouthwest
Deal found 9/10$197
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:50 amPWM - CLT
1 stop10h 29mAmerican Airlines
Sat 11/18:37 pmCLT - PWM
Nonstop2h 25mAmerican Airlines
Deal found 9/10$209
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/37:02 amPWM - CLT
Nonstop2h 43mAmerican Airlines
Mon 11/31:00 pmCLT - PWM
1 stop10h 59mAmerican Airlines
Deal found 9/10$217
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:38 pmPWM - CHS
1 stop6h 22mDelta
Thu 11/138:00 amCHS - PWM
1 stop4h 30mDelta
Deal found 9/11$217
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amPWM - SAV
1 stop4h 10mAmerican Airlines
Wed 10/222:47 pmSAV - PWM
1 stop5h 35mAmerican Airlines
Deal found 9/10$219
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:43 amPWM - CHS
2 stops9h 03mAmerican Airlines
Thu 11/137:44 pmCHS - PWM
1 stop4h 15mAmerican Airlines
Deal found 9/11$222
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:34 pmPWM - CHS
1 stop6h 26mAmerican Airlines
Sat 11/19:01 amCHS - PWM
2 stops6h 09mAmerican Airlines
Deal found 9/10$223
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:38 pmPWM - CHS
1 stop6h 22mDelta
Tue 10/285:52 pmCHS - PWM
1 stop5h 17mDelta
Deal found 9/10$228
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:02 amPWM - CLT
Nonstop2h 43mAmerican Airlines
Mon 11/101:00 pmCLT - PWM
1 stop10h 59mAmerican Airlines
Deal found 9/10$231
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:33 amPWM - SAV
1 stop9h 27mDelta
Fri 10/37:10 amSAV - PWM
1 stop17h 24mDelta
Deal found 9/10$233

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Tue 11/4

7:02 am-11:35 am

1 stop4h 33m

Myrtle Beach Intl

Sat 11/15

3:56 pm-9:47 pm

1 stop5h 51m

$193

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 12/12

6:05 pm-8:43 pm

Nonstop2h 38m

Charleston

Fri 12/26

3:04 pm-5:25 pm

Nonstop2h 21m

$194

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Sat 11/15

3:15 pm-7:50 pm

1 stop4h 35m

Charleston

Wed 12/3

5:45 pm-10:15 pm

1 stop4h 30m

$197

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Sat 11/8

2:38 pm-9:00 pm

1 stop6h 22m

Charleston

Thu 11/13

8:00 am-12:30 pm

1 stop4h 30m

$217

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 10/22

6:50 am-12:10 pm

1 stop5h 20m

Charleston

Sat 11/1

6:52 pm-12:05 am

1 stop5h 13m

$217

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Thu 12/11

12:23 pm-7:16 pm

1 stop6h 53m

Charleston

Mon 12/15

5:38 pm-9:37 pm

1 stop3h 59m

$217

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Mon 2/23

5:30 am-1:45 pm

1 stop8h 15m

Charleston

Fri 2/27

2:25 pm-9:59 pm

1 stop7h 34m

$228

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 10/24

2:38 pm-9:00 pm

1 stop6h 22m

Charleston

Tue 10/28

5:52 pm-11:09 pm

1 stop5h 17m

$228

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Mon 2/23

5:06 pm-7:48 pm

Nonstop2h 42m

Charleston

Fri 2/27

2:02 pm-4:26 pm

Nonstop2h 24m

$232

PortlandSavannah

PWM - SAV

PWMSAV

Portland

Tue 9/23

1:40 pm-11:38 pm

1 stop9h 58m

Savannah/Hilton Head

Fri 10/3

7:10 am-12:34 am

1 stop17h 24m

$233

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 60 results
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6

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $217). Flying from Portland, Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Portland, Maine to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Southwest, Breeze Airways, and Delta from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Breeze Airways
8.0
Very good
205 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PWM), located 2.9 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How popular is this Portland, Maine to South Carolina flight route?

    Flights from Portland to South Carolina have been viewed 3 times in the past calendar month.

  • How long is the flight from Portland, Maine to South Carolina?

    For as low as $194, American Airlines can have you in South Carolina from Portland, Maine in 2h 38m. There are 909 mi between Portland, Maine and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?

    One-way options have recently been found by users for as low as $45 on Breeze Airways. Other airlines that offer cheap prices include Southwest from $90 and American Airlines from $109 one-way.

  • What are the most popular routes from Portland, Maine to South Carolina?

    When deciding which route to take from Portland, Maine to South Carolina consider Portland - Charlotte Douglas, Portland - Charleston or Portland - Savannah/Hilton Head as they are the most popular.

  • What are the cheapest flights from Portland, Maine to South Carolina?

    Looking for the cheapest flight from Portland, Maine to South Carolina? While on average our users pay $183, our data indicates the cheapest price to be $63. The most popular route (Portland - Charlotte Douglas), is priced around $299.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $217). Flying from Portland, Maine to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$178FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$150Average$343FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$188Average$365FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$236Average$396FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$256Average$429FlexibilityNo cancel feeOn-time63%

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