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South Carolina

$67+ Cheap flights from Portland, ME (PWM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Booking.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
PWM
-
CHS
Nonstop2h 35m
Breeze Airways
Wed 5/132:55 pm
CHS
-
PWM
Nonstop2h 25m
Breeze Airways
Deal found 1/26$124
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:13 pm
PWM
-
CHS
Nonstop2h 35m
Breeze Airways
Mon 8/313:08 pm
CHS
-
PWM
Nonstop2h 25m
Breeze Airways
Deal found 1/27$142
This Travelocity deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
PWM
-
CHS
Nonstop2h 35m
Multiple Airlines
Wed 5/133:30 pm
CHS
-
PWM
1 stop8h 06m
Multiple Airlines
Deal found 1/26$148
This JetBlue deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:18 pm
PWM
-
CHS
1 stop4h 47m
JetBlue
Wed 5/133:30 pm
CHS
-
PWM
1 stop8h 06m
JetBlue
Deal found 1/25$163
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:06 pm
PWM
-
CHS
Nonstop2h 42m
Breeze Airways
Mon 2/92:02 pm
CHS
-
PWM
Nonstop2h 24m
Breeze Airways
Deal found 1/26$170
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:06 pm
PWM
-
CHS
Nonstop2h 42m
Breeze Airways
Mon 5/42:02 pm
CHS
-
PWM
Nonstop2h 24m
Breeze Airways
Deal found 1/27$172
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:13 pm
PWM
-
CHS
Nonstop2h 35m
Breeze Airways
Mon 8/103:08 pm
CHS
-
PWM
Nonstop2h 25m
Breeze Airways
Deal found 1/27$176
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/65:06 pm
PWM
-
CHS
Nonstop2h 42m
Breeze Airways
Fri 2/132:02 pm
CHS
-
PWM
Nonstop2h 24m
Breeze Airways
Deal found 1/25$191
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:13 pm
PWM
-
CHS
Nonstop2h 35m
Breeze Airways
Mon 5/253:08 pm
CHS
-
PWM
Nonstop2h 25m
Breeze Airways
Deal found 1/26$207
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:06 pm
PWM
-
CHS
Nonstop2h 42m
Breeze Airways
Fri 2/272:02 pm
CHS
-
PWM
Nonstop2h 24m
Breeze Airways
Deal found 1/26$210
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:29 am
PWM
-
MYR
1 stop4h 49m
American Airlines
Tue 2/245:40 pm
MYR
-
PWM
2 stops6h 10m
American Airlines
Deal found 1/26$285
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/284:30 pm
PWM
-
SAV
1 stop5h 10m
Southwest
Wed 3/47:45 am
SAV
-
PWM
1 stop7h 05m
Southwest
Deal found 1/27$290

Find flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$124
(Booking.com)

One-way from

$86
(Booking.com)

Popular in

April

Cheapest in

August

Average price

$370

Good round-trip deal

$163 or less

Good one-way deal

$81 or less
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
Search Deals
From Portland to South Carolina
Search Deals
One-way flight from Portland to South Carolina
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Portland to South Carolina.
Search Deals
Price to beat on a one-way flight from Portland to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 5/6

6:05 pm-8:40 pm

Nonstop2h 35m

Charleston

Wed 5/13

3:30 pm-11:36 pm

1 stop8h 06m

$148

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Wed 5/6

2:18 pm-7:05 pm

1 stop4h 47m

Charleston

Wed 5/13

3:30 pm-11:36 pm

1 stop8h 06m

$163

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 5/1

5:06 pm-7:48 pm

Nonstop2h 42m

Charleston

Mon 5/4

2:02 pm-4:26 pm

Nonstop2h 24m

$173

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 2/20

5:06 pm-7:48 pm

Nonstop2h 42m

Charleston

Fri 2/27

2:02 pm-4:26 pm

Nonstop2h 24m

$222

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Sat 5/9

6:00 am-10:15 am

1 stop4h 15m

Charleston

Mon 5/11

3:30 pm-11:36 pm

1 stop8h 06m

$232

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 5/29

6:13 pm-8:48 pm

Nonstop2h 35m

Charleston

Mon 6/1

3:08 pm-5:33 pm

Nonstop2h 25m

$248

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 5/29

2:18 pm-7:05 pm

1 stop4h 47m

Charleston

Mon 6/1

3:30 pm-11:36 pm

1 stop8h 06m

$272

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Thu 5/28

2:18 pm-7:05 pm

1 stop4h 47m

Charleston

Tue 6/2

3:30 pm-11:36 pm

1 stop8h 06m

$272

PortlandCharleston

PWM - CHS

PWMCHS

Portland

Fri 2/20

5:07 pm-11:51 pm

2 stops6h 44m

Charleston

Fri 2/27

6:36 pm-10:59 pm

1 stop4h 23m

$282

PortlandMyrtle Beach

PWM - MYR

PWMMYR

Portland

Sat 2/21

7:00 am-2:26 pm

2 stops7h 26m

Myrtle Beach Intl

Tue 2/24

5:40 pm-10:30 pm

1 stop4h 50m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 60 results
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6

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland, Maine to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $58). Flying from Portland, Maine to South Carolina in January is currently the most expensive (average of $83). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

One of the essential ways to save on airfare from Portland, Maine to South Carolina is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 63% on airfare.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 28, 2026.
Read reviews from past customers who have flown Breeze Airways, Southwest, and Delta from Portland to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
263 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Entertainment

6.6

Boarding

8.3

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.2
Very good
263 reviews
Breeze Airways
8.2
Very good
263 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Entertainment

6.6

Boarding

8.3

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Southwest
8.0
Very good
4,267 reviews
Breeze Airways
8.2
Very good
263 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Entertainment

6.6

Boarding

8.3

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,124 reviews
Breeze Airways
8.2
Very good
263 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Entertainment

6.6

Boarding

8.3

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.2
Good
11,201 reviews
Breeze Airways
8.2
Very good
263 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Entertainment

6.6

Boarding

8.3

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PWM), located 2.9 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How popular is this Portland, Maine to South Carolina flight route?

    Flights from Portland to South Carolina have been viewed 7 times in the past calendar month.

  • How long is the flight from Portland, Maine to South Carolina?

    For as low as $124, Breeze Airways can have you in South Carolina from Portland, Maine in 2h 35m. There are 909 mi between Portland, Maine and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland, Maine to South Carolina one-way?

    One-way options have recently been found by users for as low as $46 on Breeze Airways. Other airlines that offer cheap prices include Southwest from $97 and American Airlines from $118 one-way.

  • What are the most popular routes from Portland, Maine to South Carolina?

    When deciding which route to take from Portland, Maine to South Carolina consider Portland - Charlotte Douglas, Portland - Myrtle Beach Intl or Portland - Charleston as they are the most popular.

  • What are the cheapest flights from Portland, Maine to South Carolina?

    Looking for the cheapest flight from Portland, Maine to South Carolina? While on average our users pay $335, our data indicates the cheapest price to be $49. The most popular route (Portland - Charlotte Douglas), is priced around $327.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to South Carolina (average of $58). Flying from Portland, Maine to South Carolina in January is currently the most expensive (average of $83). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

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Top 4 airlines flying from Portland to South Carolina

Discover the top 4 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$170FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$147Average$342FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$236Average$430FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$236Average$385FlexibilityNo cancel feeOn-time71%

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