South Carolina

$236+ Cheap flights from Moline (MLI) to South Carolina

MLI — CHS
Dec 9 — Dec 161
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Cheap flight deals from Moline to South Carolina

Cheapest flights from Moline to South Carolina

Sat 12/56:42 am -
1 stop6h 18m
Sat 12/1212:10 pm -
1 stop7h 04m
Deal found 11/5$296
Sat 12/56:10 am -
1 stop4h 40m
Thu 12/105:34 pm -
1 stop6h 27m
Deal found 11/5$325
Sat 12/54:10 pm -
1 stop5h 58m
Thu 12/105:04 am -
2 stops6h 52m
Deal found 11/5$330
Fri 12/1111:08 am -
1 stop4h 19m
Sun 12/136:59 pm -
1 stop5h 02m
Deal found 11/4$349
Thu 11/2611:22 am -
1 stop4h 10m
Wed 12/211:58 am -
1 stop4h 44m
Deal found 11/4$349
Sat 11/215:13 pm -
1 stop5h 46m
Thu 11/267:05 am -
1 stop6h 02m
Deal found 11/4$363
Sun 11/225:13 pm -
1 stop5h 46m
Thu 11/267:05 am -
1 stop6h 02m
Deal found 11/4$364
Thu 12/106:10 am -
1 stop6h 23m
Tue 12/156:00 am -
1 stop5h 26m
Deal found 11/5$366
Sun 11/225:46 am -
2 stops9h 22m
Thu 11/267:00 am -
1 stop4h 52m
Deal found 11/4$369
Sat 11/215:13 pm -
1 stop5h 46m
Mon 11/235:34 pm -
1 stop6h 34m
Deal found 11/4$378
Fri 12/45:19 pm -
1 stop4h 28m
Mon 12/76:00 am -
1 stop5h 26m
Deal found 11/8$384
Wed 12/1611:26 am -
1 stop5h 49m
Sat 12/268:36 pm -
1 stop4h 40m
Deal found 11/8$389

Find flight deals from Moline to South Carolina

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(Delta)

One-way from

$236
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$991
Provider with most accurate pricing for Moline Quad-City-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Moline Quad-City-Myrtle Beach Intl flights.
From Moline Quad-City to South Carolina
One-way flight from Moline Quad-City to South Carolina
Highest demand for flights based on searches. 25% potential increase in price ($152 potential increase over avg. RT price).
Cheapest flight prices on average. 12% potential price decrease ($50 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Moline to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Wed 11/25

6:13 pm-10:36 pm

2 stops27h 23m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$236

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Mon 11/30

2:31 pm-9:43 pm

1 stop6h 12m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$289
Quickest round-trip

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 12/10

11:08 am-4:27 pm

1 stop4h 19m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$289

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 1/28

8:15 am-1:46 pm

1 stop4h 31m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$289

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 1/28

7:10 am-6:34 pm

2 stops10h 24m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$294

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 12/10

6:42 am-3:32 pm

2 stops7h 50m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$294

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Mon 11/30

1:38 pm-9:48 am

3 stops43h 10m

Charleston

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$297

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Sat 3/6

11:15 am-6:11 pm

1 stop5h 56m

Charleston

Tue 3/9

4:30 pm-10:30 pm

1 stop7h 00m

$301

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Fri 1/15

2:26 pm-11:59 pm

2 stops8h 33m

Charleston

Tue 1/19

2:42 pm-9:44 pm

2 stops8h 02m

$336

MolineCharleston

MLI Moline Quad-City - CHS Charleston

MLICHS

Moline Quad-City

Thu 4/1

6:03 pm-12:21 am

1 stop5h 18m

Charleston

Mon 4/5

6:18 am-10:51 am

1 stop5h 33m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/7

Showing 1-10 of 26 resultsSorted by cheapest first
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Best time to book a flight from Moline to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Moline with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Moline to South Carolina

What is the cheapest month to book a flight from Moline to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Moline to South Carolina (average of $344). Flying from Moline to South Carolina in April is currently the most expensive (average of $506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Moline to South Carolina?

Airfare is below average for this route at the moment.
Moline to South Carolina flights typically cost between $294 and $388 in April.
The cheapest round-trip price found within the last 5 days was $291 on Delta (Apr 3-Apr 7).

Reviews of airlines servicing South Carolina

See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Moline to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Comfort

7.8

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • What airport do you fly from for flights from Moline to South Carolina?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to South Carolina. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • How long is the flight from Moline to South Carolina?

    There are many flights that can get you from Moline to South Carolina in 5h 18m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. Airlines will cover a distance of 824 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Moline to South Carolina?

  • Can I find deals for flights from Moline to South Carolina that include hotel bookings?

    Yes. In addition to deals on Moline to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South Carolina.

  • Can I find deals for business class flights from Moline to South Carolina?

    Yes. Cheapflights offers flight deals from Moline to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Moline to South Carolina (average of $344). Flying from Moline to South Carolina in April is currently the most expensive (average of $506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Moline to South Carolina

Top 3 airlines flying from Moline to South Carolina

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$260Average$384FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$260Average$430FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$367FlexibilityNo cancel feeOn-timeN/A

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