$126+ Cheap flights from Milwaukee (MKE) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Milwaukee to South Carolina
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Cheapest flights from Milwaukee to South CarolinaExplore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:15 am -
1 stop21h 22m
Wed 10/149:42 pm -
1 stop12h 38m
Deal found 9/8![Frontier logo]()
$256
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:33 am -
1 stop5h 35m
Wed 11/114:37 pm -
1 stop7h 00m
Deal found 9/8![American Airlines logo]()
$259
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:11 pm -
1 stop5h 23m
Wed 11/256:00 am -
1 stop12h 26m
Deal found 9/7![Frontier logo]()
$260
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:42 am -
1 stop5h 15m
Tue 10/275:37 pm -
1 stop4h 15m
Deal found 9/4![United Airlines logo]()
$266
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:15 am -
1 stop5h 50m
Sat 11/146:05 am -
1 stop28h 11m
Deal found 9/6![Frontier logo]()
$268
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:10 pm -
1 stop5h 09m
Sat 10/315:00 am -
1 stop6h 14m
Deal found 9/4![American Airlines logo]()
$271
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:33 pm -
1 stop26h 11m
Sun 12/69:39 pm -
1 stop19h 59m
Deal found 9/4![Frontier logo]()
$272
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:59 pm -
1 stop6h 52m
Mon 10/127:14 pm -
1 stop5h 39m
Deal found 9/8![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 pm -
1 stop5h 28m
Sat 10/108:30 pm -
1 stop4h 27m
Deal found 9/5![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:10 am -
1 stop4h 27m
Tue 10/132:13 pm -
1 stop7h 14m
Deal found 9/6![American Airlines logo]()
$295
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:11 pm -
1 stop5h 23m
Mon 11/236:50 pm -
1 stop23h 36m
Deal found 9/8![Frontier logo]()
$296
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops7h 17m
Sat 11/75:37 pm -
1 stop4h 13m
Deal found 9/5![United Airlines logo]()
$296
Best flights from Milwaukee to South CarolinaDiscover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:42 am -
1 stop5h 15m
Tue 10/275:37 pm -
1 stop4h 15m
Deal found 9/4![United Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:10 am -
1 stop4h 27m
Tue 10/132:13 pm -
1 stop7h 14m
Deal found 9/6![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:45 pm -
1 stop4h 02m
Sat 11/712:00 pm -
1 stop6h 25m
Deal found 9/5![Delta logo]()
$328
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/184:15 pm -
1 stop5h 30m
Sat 10/248:25 am -
1 stop4h 55m
Deal found 9/7![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:47 am -
1 stop5h 43m
Sun 11/225:37 pm -
1 stop4h 13m
Deal found 9/8![United Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:49 pm -
1 stop5h 39m
Tue 10/66:58 pm -
1 stop5h 55m
Deal found 9/9![Delta logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:03 am -
1 stop7h 07m
Tue 10/65:11 pm -
1 stop4h 16m
Deal found 9/5![American Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:15 am -
2 stops9h 25m
Fri 10/97:35 pm -
1 stop5h 15m
Deal found 9/8![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:59 pm -
1 stop5h 18m
Wed 11/112:43 pm -
1 stop3h 53m
Deal found 9/7![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:03 pm -
1 stop3h 53m
Wed 11/185:50 am -
2 stops10h 08m
Deal found 9/8![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:55 am -
2 stops9h 15m
Fri 10/98:45 pm -
1 stop4h 35m
Deal found 9/8![Southwest logo]()
$360
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:38 am -
1 stop5h 28m
Mon 11/164:37 pm -
1 stop7h 00m
Deal found 9/6![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:20 am -
1 stop4h 06m
Sat 11/1412:55 pm -
1 stop5h 41m
Deal found 9/8![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:52 pm -
2 stops7h 23m
Tue 10/136:50 pm -
1 stop5h 09m
Deal found 9/8![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:30 pm -
1 stop4h 45m
Thu 10/226:50 am -
1 stop3h 55m
Deal found 9/8![Southwest logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:58 pm -
1 stop7h 02m
Wed 11/1111:21 am -
1 stop6h 17m
Deal found 9/4![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:41 pm -
1 stop4h 17m
Sat 11/146:00 am -
1 stop4h 15m
Deal found 9/8![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:48 am -
2 stops11h 12m
Sat 11/75:50 am -
2 stops8h 42m
Deal found 9/8![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
1 stop7h 06m
Fri 11/134:11 pm -
1 stop5h 52m
Deal found 9/8![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:00 am -
2 stops9h 20m
Sat 11/78:20 am -
2 stops8h 50m
Deal found 9/4![Southwest logo]()
$383
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop4h 16m
Sat 10/319:00 am -
1 stop5h 27m
Deal found 9/4![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops7h 17m
Sat 10/315:37 pm -
1 stop4h 13m
Deal found 9/8![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:10 am -
2 stops6h 05m
Tue 10/131:55 pm -
2 stops10h 05m
Deal found 9/8![Southwest logo]()
$387
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:03 am -
1 stop5h 11m
Mon 10/195:59 pm -
1 stop4h 24m
Deal found 9/8![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 am -
2 stops9h 42m
Sun 11/112:12 pm -
1 stop5h 26m
Deal found 9/5![American Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:07 am -
1 stop5h 04m
Wed 11/1811:27 am -
1 stop7h 39m
Deal found 9/8![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:15 pm -
1 stop3h 50m
Sun 11/156:40 am -
1 stop4h 05m
Deal found 9/8![Southwest logo]()
$388
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:30 am -
1 stop4h 13m
Sun 10/115:40 am -
1 stop4h 31m
Deal found 9/6![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
2 stops7h 21m
Sat 9/2610:23 am -
2 stops9h 46m
Deal found 9/7![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:55 am -
2 stops6h 40m
Mon 10/128:40 pm -
1 stop4h 40m
Deal found 9/8![Southwest logo]()
$394
Last-minute flights from Milwaukee to South CarolinaDiscover last-minute flight deals from Milwaukee to South Carolina. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to South Carolina. Data last updated September 9, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:10 am -
1 stop7h 11m
Sat 9/129:40 pm -
1 stop12h 42m
Deal found 9/6![Frontier logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:03 am -
1 stop7h 07m
Tue 10/65:11 pm -
1 stop4h 16m
Deal found 9/6![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:20 pm -
1 stop5h 57m
Sat 10/36:00 am -
1 stop5h 48m
Deal found 9/9![United Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:10 am -
1 stop4h 27m
Tue 10/132:13 pm -
1 stop7h 14m
Deal found 9/6![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:59 pm -
1 stop6h 52m
Mon 10/127:14 pm -
1 stop5h 39m
Deal found 9/8![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 pm -
1 stop5h 28m
Sat 10/108:30 pm -
1 stop4h 27m
Deal found 9/5![American Airlines logo]()
$295
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:15 am -
1 stop21h 22m
Mon 10/129:42 pm -
1 stop12h 38m
Deal found 9/5![Frontier logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:15 am -
1 stop21h 22m
Wed 10/149:42 pm -
1 stop12h 38m
Deal found 9/8![Frontier logo]()
$256
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:42 am -
1 stop5h 15m
Tue 10/275:37 pm -
1 stop4h 15m
Deal found 9/4![United Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:10 pm -
1 stop5h 09m
Sat 10/315:00 am -
1 stop6h 14m
Deal found 9/4![American Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops7h 17m
Sat 11/75:37 pm -
1 stop4h 13m
Deal found 9/5![United Airlines logo]()
$296
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:33 am -
1 stop5h 35m
Wed 11/114:37 pm -
1 stop7h 00m
Deal found 9/8![American Airlines logo]()
$259
One-way flights from Milwaukee to South CarolinaSearch for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:15 am -
1 stop29h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Frontier logo]()
$126
This Priceline deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:15 am -
1 stop5h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$129
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:04 am -
1 stop5h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:50 am -
1 stop9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$135
This Travelocity deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:15 am -
1 stop21h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$137
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$139
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:15 am -
1 stop21h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:10 am -
1 stop21h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:33 pm -
1 stop26h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$148
This Frontier deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:10 am -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:33 pm -
1 stop13h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:03 pm -
1 stop11h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Frontier logo]()
$168
Find flight deals from Milwaukee to South Carolina
Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $256 (Kiwi.com) |
One-way from | $126 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $387 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Mon 11/2
5:04 am-11:07 am
1 stop5h 03m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$130
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Mon 11/2
4:50 pm-10:55 pm
2 stops5h 05m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$135
MilwaukeeSavannah
MKE Milwaukee-Mitchell - SAV Savannah/Hilton Head
MKESAV
Milwaukee-Mitchell
Mon 12/14
5:10 am-11:38 am
1 stop5h 28m
Savannah/Hilton Head
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
MilwaukeeCharleston
MKE Milwaukee-Mitchell - CHS Charleston
MKECHS
Milwaukee-Mitchell
Mon 3/1
6:38 pm-11:58 pm
1 stop4h 20m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
MilwaukeeCharleston
MKE Milwaukee-Mitchell - CHS Charleston
MKECHS
Milwaukee-Mitchell
Wed 10/21
5:30 am-11:35 am
1 stop5h 05m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
MilwaukeeSavannah
MKE Milwaukee-Mitchell - SAV Savannah/Hilton Head
MKESAV
Milwaukee-Mitchell
Mon 12/14
5:00 am-2:41 pm
2 stops8h 41m
Savannah/Hilton Head
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Mon 10/19
6:20 am-1:35 pm
1 stop6h 15m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Fri 10/2
2:20 pm-9:17 pm
1 stop5h 57m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Tue 10/13
5:00 am-9:58 am
1 stop3h 58m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
MilwaukeeMyrtle Beach
MKE Milwaukee-Mitchell - MYR Myrtle Beach Intl
MKEMYR
Milwaukee-Mitchell
Fri 1/8
7:30 am-1:05 pm
1 stop4h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$187
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
MKE-CLT
MKE-GSP
MKE-CAE
MKE-HHH
MKE-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to South Carolina
MKE-USSC
MKE-CLT
MKE-GSP
MKE-CAE
MKE-HHH
What is the cheapest month to book a flight from Milwaukee to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $349). Flying from Milwaukee to South Carolina in June is currently the most expensive (average of $425). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Milwaukee to South Carolina?
Airfare is below average for this route at the moment.
Milwaukee to South Carolina flights typically cost between $446 and $528 in October.The cheapest round-trip price found within the last 5 days was $339 on American Airlines (Oct 6-Oct 13).
How far ahead should I book a flight from Milwaukee to South Carolina?
The best time to book flights from Milwaukee to South Carolina is 7 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 9, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Milwaukee to South Carolina by cabin class
Find flights from Milwaukee to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Milwaukee and South Carolina flights
Browse other Milwaukee and South Carolina flight options. Last updated on September 9, 2026.
Popular flight searches
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Milwaukee to South Carolina flights
Consider these flights traveling from Milwaukee to South Carolina.
Top 4 airlines flying from Milwaukee to South Carolina
Discover the top 4 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$290 | Average$448 | FlexibilityNo cancel fee | On-time63% |