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South Carolina

$91+ Cheap flights from Milwaukee (MKE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Milwaukee to South Carolina

Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$195
(JetBlue)

One-way from

$91
(Southwest)

Popular in

March

Cheapest in

October

Average price

$368
From Milwaukee-Mitchell to South Carolina
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One-way flight from Milwaukee-Mitchell to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Milwaukee to South Carolina

Cheapest flights from Milwaukee to South Carolina
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This JetBlue deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/54:29 pmMKE - CHS
1 stop5h 49mJetBlue
lun. 9/87:00 amCHS - MKE
1 stop9h 33mJetBlue
Deal found 6/9$195
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/232:54 pmMKE - CLT
1 stop4h 39mDelta
sáb. 8/3011:21 amCLT - MKE
1 stop6h 16mDelta
Deal found 6/12$197
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/1912:10 pmMKE - MYR
1 stop7h 36mSpirit Airlines
dom. 9/2112:18 pmMYR - MKE
1 stop19h 22mSpirit Airlines
Deal found 6/9$214
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/712:02 pmMKE - CLT
1 stop5h 59mSpirit Airlines
lun. 7/146:20 amCLT - MKE
1 stop10h 22mSpirit Airlines
Deal found 6/9$219
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/96:45 amMKE - CAE
1 stop6h 32mDelta
jue. 8/145:40 amCAE - MKE
1 stop6h 19mDelta
Deal found 6/10$229
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/176:03 amMKE - CAE
1 stop6h 21mAmerican Airlines
mar. 9/306:15 amCAE - MKE
2 stops8h 48mAmerican Airlines
Deal found 6/9$234
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/136:32 amMKE - HHH
1 stop5h 12mAmerican Airlines
lun. 8/185:28 pmHHH - MKE
1 stop6h 36mAmerican Airlines
Deal found 6/10$234
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/236:00 amMKE - CAE
2 stops7h 15mUnited Airlines
mar. 9/302:53 pmCAE - MKE
2 stops8h 03mUnited Airlines
Deal found 6/9$239
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/279:01 amMKE - CHS
1 stop4h 30mSpirit Airlines
lun. 6/303:31 pmCHS - MKE
2 stops27h 34mSpirit Airlines
Deal found 6/10$255
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/205:30 pmMKE - MYR
1 stop5h 19mDelta
lun. 8/256:56 pmMYR - MKE
1 stop5h 40mDelta
Deal found 6/10$271
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/212:20 pmMKE - SAV
1 stop5h 24mDelta
lun. 10/66:30 pmSAV - MKE
1 stop5h 55mDelta
Deal found 6/12$271
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/231:35 pmMKE - CHS
1 stop4h 43mAmerican Airlines
lun. 10/278:46 pmCHS - MKE
1 stop4h 16mAmerican Airlines
Deal found 6/11$271

Cheapflights Fare Finder

Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.

Fly from

Milwaukee

Fly to

South Carolina

Route

Depart

Return

Price

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

vie. 9/5

4:29 pm-11:18 pm

1 stop5h 49m

Charleston

lun. 9/8

7:00 am-3:33 pm

1 stop9h 33m

$195

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

sáb. 8/23

2:54 pm-8:33 pm

1 stop4h 39m

Charlotte Douglas

sáb. 8/30

11:21 am-4:37 pm

1 stop6h 16m

$197

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

vie. 9/19

12:10 pm-8:46 pm

1 stop7h 36m

Myrtle Beach Intl

dom. 9/21

12:18 pm-6:40 am

1 stop19h 22m

$214

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

lun. 7/7

12:02 pm-7:01 pm

1 stop5h 59m

Charlotte Douglas

lun. 7/14

6:20 am-3:42 pm

1 stop10h 22m

$219

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

mié. 7/9

5:40 am-10:15 am

1 stop3h 35m

Columbia Metropolitan

mar. 8/19

9:56 am-1:49 pm

1 stop4h 53m

$229

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

mié. 9/17

6:03 am-1:24 pm

1 stop6h 21m

Columbia Metropolitan

mar. 9/30

6:15 am-2:03 pm

2 stops8h 48m

$234

MilwaukeeHilton Head Island

MKE - HHH

MKEHHH

Milwaukee-Mitchell

mié. 8/13

6:32 am-12:44 pm

1 stop5h 12m

Hilton Head Island

lun. 8/18

5:28 pm-11:04 pm

1 stop6h 36m

$234

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

mar. 9/23

6:00 am-2:15 pm

2 stops7h 15m

Columbia Metropolitan

mar. 9/30

2:53 pm-9:56 pm

2 stops8h 03m

$239

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

vie. 6/27

9:01 am-2:31 pm

1 stop4h 30m

Charleston

lun. 6/30

3:31 pm-6:05 pm

2 stops27h 34m

$255

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

mié. 8/20

5:30 pm-11:49 pm

1 stop5h 19m

Myrtle Beach Intl

lun. 8/25

6:56 pm-11:36 pm

1 stop5h 40m

$271

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 results
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Best time to book a flight from Milwaukee to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to South Carolina

What is the cheapest month to book a flight from Milwaukee to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SC?

Find hourly flight availability from Milwaukee to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Milwaukee to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
To help decide which airline to fly from Milwaukee to South Carolina, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
JetBlue
7.3
Good
2,925 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to South Carolina?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to South Carolina.

  • What are the cheapest airlines to fly from Milwaukee to South Carolina one-way?

    For one-way options, check prices for Southwest. According to our data, you can fly for as low as $91. Users have also found prices from $99 and $101 on Delta and Spirit Airlines, respectively.

  • What are the most popular routes from Milwaukee to South Carolina?

    While some choose either Milwaukee-Mitchell - Myrtle Beach Intl or Milwaukee-Mitchell - Charleston, Milwaukee-Mitchell - Savannah/Hilton Head is the most popular route from Milwaukee to South Carolina.

  • Can I find deals for flights from Milwaukee to South Carolina that include hotel bookings?

    Yes. In addition to deals on Milwaukee to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to South Carolina.

  • Can I find deals for business class flights from Milwaukee to South Carolina?

    Yes. Cheapflights offers flight deals from Milwaukee to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Milwaukee to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Milwaukee to South Carolina

Discover the top 5 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$141Average$244FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$211Average$369FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$366FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$376FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$256Average$403FlexibilityNo cancel feeOn-time63%

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