$124+ Cheap flights from Milwaukee (MKE) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Milwaukee to South CarolinaExplore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:08 am -
1 stop4h 41m
Fri 11/2711:19 am -
1 stop6h 19m
Deal found 11/1![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:20 am -
1 stop6h 50m
Wed 12/92:50 pm -
2 stops8h 30m
Deal found 11/1![Southwest logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:11 pm -
1 stop13h 39m
Mon 11/232:41 pm -
1 stop27h 45m
Deal found 10/31![Multiple Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:49 pm -
1 stop4h 03m
Wed 1/65:32 pm -
1 stop3h 59m
Deal found 11/1![American Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:45 am -
1 stop5h 01m
Wed 1/62:59 pm -
2 stops7h 00m
Deal found 11/1![United Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:12 pm -
1 stop6h 35m
Sat 12/54:04 pm -
1 stop7h 24m
Deal found 11/3![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:00 am -
1 stop6h 22m
Sat 12/52:00 pm -
1 stop7h 00m
Deal found 10/31![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:00 am -
1 stop4h 16m
Thu 12/106:00 am -
1 stop6h 17m
Deal found 11/3![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm -
1 stop4h 43m
Thu 11/2612:58 pm -
1 stop5h 38m
Deal found 10/31![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:33 pm -
1 stop4h 25m
Fri 11/2710:27 am -
2 stops8h 39m
Deal found 11/1![United Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:00 am -
2 stops8h 27m
Thu 12/106:15 am -
1 stop4h 48m
Deal found 11/3![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:34 pm -
1 stop4h 20m
Sat 12/510:18 am -
2 stops10h 42m
Deal found 11/3![American Airlines logo]()
$344
Best flights from Milwaukee to South CarolinaDiscover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:20 am -
1 stop6h 50m
Wed 12/92:50 pm -
2 stops8h 30m
Deal found 11/1![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:45 am -
1 stop5h 01m
Wed 1/62:59 pm -
2 stops7h 00m
Deal found 11/1![United Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:12 pm -
1 stop6h 35m
Sat 12/56:00 am -
1 stop6h 48m
Deal found 10/31![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:37 pm -
2 stops10h 17m
Sat 12/512:11 pm -
2 stops8h 49m
Deal found 10/31![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:45 am -
2 stops10h 30m
Sat 1/910:10 am -
2 stops9h 45m
Deal found 11/1![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm -
1 stop4h 43m
Thu 11/2612:58 pm -
1 stop5h 38m
Deal found 10/31![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop5h 02m
Mon 12/75:00 pm -
1 stop4h 55m
Deal found 11/2![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:43 pm -
1 stop4h 21m
Fri 12/45:34 pm -
1 stop7h 25m
Deal found 11/1![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:33 pm -
1 stop4h 25m
Fri 11/2710:27 am -
2 stops8h 39m
Deal found 11/1![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:15 pm -
1 stop4h 20m
Thu 12/101:30 pm -
2 stops9h 00m
Deal found 11/1![Southwest logo]()
$344
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:17 am -
1 stop7h 27m
Sat 11/215:47 pm -
1 stop7h 05m
Deal found 11/2![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:00 am -
2 stops8h 27m
Thu 12/106:15 am -
1 stop4h 48m
Deal found 11/3![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:20 am -
1 stop7h 05m
Mon 11/307:55 pm -
1 stop4h 59m
Deal found 10/31![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:40 am -
1 stop4h 44m
Thu 11/195:47 pm -
1 stop7h 05m
Deal found 11/3![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:38 pm -
2 stops8h 21m
Tue 12/155:00 pm -
1 stop4h 55m
Deal found 11/4![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
2 stops9h 25m
Tue 12/83:25 pm -
2 stops7h 55m
Deal found 11/2![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:50 pm -
1 stop4h 12m
Wed 12/236:30 am -
1 stop6h 30m
Deal found 11/3![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 am -
1 stop6h 30m
Thu 12/317:05 pm -
1 stop5h 54m
Deal found 10/31![American Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:15 am -
2 stops9h 30m
Sun 1/176:40 am -
2 stops9h 00m
Deal found 11/3![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/203:51 pm -
1 stop4h 12m
Thu 1/2110:40 am -
1 stop4h 20m
Deal found 11/3![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:01 am -
1 stop6h 58m
Mon 12/75:40 am -
1 stop4h 33m
Deal found 11/3![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:17 am -
1 stop3h 56m
Sun 11/228:28 pm -
1 stop4h 24m
Deal found 11/2![American Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:45 am -
2 stops9h 45m
Wed 12/239:15 pm -
1 stop4h 10m
Deal found 11/3![Southwest logo]()
$386
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/191:55 pm -
2 stops9h 20m
Wed 12/239:15 pm -
1 stop4h 10m
Deal found 11/3![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:00 am -
2 stops8h 30m
Tue 1/124:25 pm -
1 stop5h 06m
Deal found 11/1![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:41 pm -
1 stop4h 18m
Sat 11/285:20 am -
1 stop4h 55m
Deal found 10/31![Delta logo]()
$408
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:23 pm -
2 stops8h 36m
Mon 11/307:00 pm -
1 stop4h 15m
Deal found 11/2![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
2 stops7h 30m
Thu 12/101:30 pm -
2 stops9h 00m
Deal found 11/4![Southwest logo]()
$413
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:44 am -
1 stop6h 48m
Mon 12/287:05 pm -
1 stop5h 54m
Deal found 10/31![American Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:00 am -
2 stops8h 24m
Mon 2/86:15 am -
1 stop4h 45m
Deal found 11/4![United Airlines logo]()
$420
Last-minute flights from Milwaukee to South CarolinaDiscover last-minute flight deals from Milwaukee to South Carolina. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to South Carolina. Data last updated November 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:11 pm -
1 stop13h 39m
Mon 11/232:41 pm -
1 stop27h 45m
Deal found 10/31![Multiple Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm -
1 stop4h 43m
Thu 11/2612:58 pm -
1 stop5h 38m
Deal found 10/31![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:08 am -
1 stop4h 41m
Fri 11/2711:19 am -
1 stop6h 19m
Deal found 11/1![American Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:33 pm -
1 stop4h 25m
Fri 11/2710:27 am -
2 stops8h 39m
Deal found 11/1![United Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:12 pm -
1 stop6h 35m
Sat 12/54:04 pm -
1 stop7h 24m
Deal found 11/3![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:34 pm -
1 stop4h 20m
Sat 12/510:18 am -
2 stops10h 42m
Deal found 11/3![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:00 am -
1 stop6h 22m
Sat 12/52:00 pm -
1 stop7h 00m
Deal found 10/31![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:00 am -
1 stop4h 16m
Thu 12/106:00 am -
1 stop6h 17m
Deal found 11/3![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:00 am -
2 stops8h 27m
Thu 12/106:15 am -
1 stop4h 48m
Deal found 11/3![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:20 am -
1 stop6h 50m
Wed 12/92:50 pm -
2 stops8h 30m
Deal found 11/1![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:49 pm -
1 stop4h 03m
Wed 1/65:32 pm -
1 stop3h 59m
Deal found 11/1![American Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:45 am -
1 stop5h 01m
Wed 1/62:59 pm -
2 stops7h 00m
Deal found 11/1![United Airlines logo]()
$320
One-way flights from Milwaukee to South CarolinaSearch for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:24 pm -
1 stop14h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$124
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:15 am -
1 stop6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![United Airlines logo]()
$130
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:24 am -
1 stop5h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$169
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:40 am -
1 stop6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:23 pm -
2 stops8h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$175
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1311:25 am -
1 stop6h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$180
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:39 am -
2 stops9h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$218
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:25 pm -
1 stop4h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![American Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:49 pm -
1 stop4h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$242
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/158:10 am -
1 stop5h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:11 pm -
3 stops38h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:11 pm -
2 stops25h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$254
Find flight deals from Milwaukee to South Carolina
Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (American Airlines) |
One-way from | $124 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Sat 12/12
9:15 am-4:53 pm
1 stop6h 38m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$130
MilwaukeeCharleston
MKE Milwaukee-Mitchell - CHS Charleston
MKECHS
Milwaukee-Mitchell
Fri 12/4
5:00 am-3:32 pm
2 stops9h 32m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
MilwaukeeCharleston
MKE Milwaukee-Mitchell - CHS Charleston
MKECHS
Milwaukee-Mitchell
Fri 11/27
2:23 pm-11:59 pm
2 stops8h 36m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
MilwaukeeMyrtle Beach
MKE Milwaukee-Mitchell - MYR Myrtle Beach Intl
MKEMYR
Milwaukee-Mitchell
Sat 1/9
7:39 am-5:48 pm
2 stops9h 09m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$218
MilwaukeeMyrtle Beach
MKE Milwaukee-Mitchell - MYR Myrtle Beach Intl
MKEMYR
Milwaukee-Mitchell
Mon 11/30
6:25 pm-11:54 pm
1 stop4h 29m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Quickest round-trip
MilwaukeeCharleston
MKE Milwaukee-Mitchell - CHS Charleston
MKECHS
Milwaukee-Mitchell
Mon 12/28
6:49 pm-11:59 pm
1 stop4h 10m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$242
MilwaukeeHilton Head Island
MKE Milwaukee-Mitchell - HHH Hilton Head Island
MKEHHH
Milwaukee-Mitchell
Sat 2/13
6:45 am-6:26 pm
2 stops10h 41m
Hilton Head Island
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$246
MilwaukeeHilton Head Island
MKE Milwaukee-Mitchell - HHH Hilton Head Island
MKEHHH
Milwaukee-Mitchell
Mon 2/15
8:10 am-3:02 pm
1 stop5h 52m
Hilton Head Island
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$251
MilwaukeeMyrtle Beach
MKE Milwaukee-Mitchell - MYR Myrtle Beach Intl
MKEMYR
Milwaukee-Mitchell
Mon 11/30
6:11 pm-9:28 am
3 stops38h 17m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$252
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Thu 11/19
6:47 am-2:16 pm
2 stops6h 29m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$264
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
MKE-GSP
MKE-MYR
MKE-CHS
MKE-HHH
MKE-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to South Carolina
MKE-USSC
MKE-GSP
MKE-MYR
MKE-CHS
MKE-HHH
What is the cheapest month to book a flight from Milwaukee to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $356). Flying from Milwaukee to South Carolina in June is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Milwaukee to South Carolina?
The best time to book flights from Milwaukee to South Carolina is 55 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 4, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Milwaukee to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Milwaukee and South Carolina flights
Browse other Milwaukee and South Carolina flight options. Last updated on November 4, 2026.
Popular flight searches
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Milwaukee to South Carolina flights
Consider these flights traveling from Milwaukee to South Carolina.
Top 4 airlines flying from Milwaukee to South Carolina
Discover the top 4 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$389 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$395 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$290 | Average$439 | FlexibilityNo cancel fee | On-time63% |