$112+ Cheap flights from Milwaukee (MKE) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Aug 7 — Aug 141
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to South Carolina with Cheapflights
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Cheapest flights from Milwaukee to South CarolinaExplore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:49 pm
MKE
- MYR
1 stop5h 21m
American Airlines
Tue 8/116:04 pm
MYR
- MKE
1 stop6h 55m
American Airlines
Deal found 7/8![American Airlines logo]()
$243
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:00 am
MKE
- CHS
1 stop4h 36m
United Airlines
Mon 8/3111:40 am
CHS
- MKE
1 stop5h 30m
United Airlines
Deal found 7/7![United Airlines logo]()
$249
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/129:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/4![Frontier logo]()
$258
This Booking.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:10 pm
MKE
- CLT
1 stop23h 55m
Frontier
Sun 10/118:11 pm
CLT
- MKE
1 stop24h 04m
Frontier
Deal found 7/6![Frontier logo]()
$259
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:29 pm
MKE
- CHS
1 stop6h 30m
Delta
Tue 10/277:10 am
CHS
- MKE
1 stop6h 25m
Delta
Deal found 7/8![Delta logo]()
$259
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:45 am
MKE
- CAE
1 stop6h 35m
American Airlines
Sat 10/318:30 pm
CAE
- MKE
1 stop4h 27m
American Airlines
Deal found 7/7![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:02 pm
MKE
- MYR
1 stop3h 43m
American Airlines
Sat 9/1912:10 pm
MYR
- MKE
1 stop5h 53m
American Airlines
Deal found 7/8![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:28 am
MKE
- MYR
1 stop3h 56m
American Airlines
Thu 8/205:15 pm
MYR
- MKE
1 stop5h 32m
American Airlines
Deal found 7/7![American Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:40 am
MKE
- CLT
1 stop4h 05m
Southwest
Sat 8/227:55 am
CLT
- MKE
2 stops8h 50m
Southwest
Deal found 7/7![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:00 am
MKE
- MYR
1 stop4h 10m
Southwest
Thu 8/2710:50 am
MYR
- MKE
1 stop5h 35m
Southwest
Deal found 7/6![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:15 am
MKE
- SAV
1 stop4h 17m
Delta
Tue 10/206:30 pm
SAV
- MKE
1 stop6h 23m
Delta
Deal found 7/7![Delta logo]()
$267
This Mytrip deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:10 pm
MKE
- CLT
1 stop18h 51m
Frontier
Sat 8/229:52 pm
CLT
- MKE
1 stop14h 21m
Frontier
Deal found 7/4![Frontier logo]()
$268
Best flights from Milwaukee to South CarolinaDiscover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
Discover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:40 am
MKE
- CLT
1 stop4h 15m
Southwest
Tue 9/228:05 am
CLT
- MKE
1 stop4h 00m
Southwest
Deal found 7/7![Southwest logo]()
$258
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:14 am
MKE
- HHH
1 stop7h 05m
American Airlines
Tue 11/172:51 pm
HHH
- MKE
1 stop4h 10m
American Airlines
Deal found 7/6![American Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:22 am
MKE
- HHH
1 stop4h 10m
Delta
Tue 8/1112:15 pm
HHH
- MKE
2 stops6h 53m
Delta
Deal found 7/6![Delta logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:43 am
MKE
- GSP
1 stop21h 47m
Multiple Airlines
Mon 7/278:20 am
GSP
- MKE
1 stop24h 38m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:00 am
MKE
- MYR
1 stop4h 37m
United Airlines
Wed 12/911:25 am
MYR
- MKE
1 stop4h 39m
United Airlines
Deal found 7/7![United Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:05 pm
MKE
- MYR
1 stop4h 15m
Southwest
Thu 8/201:55 pm
MYR
- MKE
2 stops8h 30m
Southwest
Deal found 7/7![Southwest logo]()
$270
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:35 am
MKE
- CLT
1 stop4h 50m
Southwest
Thu 9/1011:50 am
CLT
- MKE
2 stops9h 00m
Southwest
Deal found 7/7![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:20 am
MKE
- CAE
1 stop7h 07m
American Airlines
Mon 9/75:51 pm
CAE
- MKE
1 stop5h 03m
American Airlines
Deal found 7/7![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:45 am
MKE
- CAE
1 stop4h 29m
Delta
Sat 8/86:11 am
CAE
- MKE
1 stop6h 28m
Delta
Deal found 7/4![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:18 am
MKE
- GSP
1 stop5h 14m
United Airlines
Sat 8/297:00 am
GSP
- MKE
2 stops11h 25m
United Airlines
Deal found 7/7![United Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:30 pm
MKE
- SAV
1 stop7h 15m
Southwest
Thu 8/274:10 pm
SAV
- MKE
2 stops6h 15m
Southwest
Deal found 7/6![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:03 am
MKE
- CHS
1 stop5h 49m
Delta
Wed 9/98:35 am
CHS
- MKE
1 stop4h 14m
Delta
Deal found 7/8![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:02 am
MKE
- HHH
1 stop7h 31m
American Airlines
Tue 7/284:55 pm
HHH
- MKE
1 stop5h 59m
American Airlines
Deal found 7/7![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am
MKE
- CAE
2 stops7h 06m
United Airlines
Mon 9/76:25 am
CAE
- MKE
1 stop7h 13m
United Airlines
Deal found 7/7![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
MKE
- MYR
2 stops11h 45m
Southwest
Sat 9/511:45 am
MYR
- MKE
2 stops7h 40m
Southwest
Deal found 7/7![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:34 am
MKE
- MYR
1 stop4h 13m
Delta
Thu 8/67:02 pm
MYR
- MKE
1 stop5h 51m
Delta
Deal found 7/3![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:32 pm
MKE
- MYR
1 stop5h 31m
American Airlines
Thu 8/66:04 pm
MYR
- MKE
1 stop6h 55m
American Airlines
Deal found 7/7![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
MKE
- HHH
2 stops8h 29m
Delta
Tue 7/284:14 pm
HHH
- MKE
1 stop7h 16m
Delta
Deal found 7/3![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:19 am
MKE
- SAV
2 stops8h 06m
United Airlines
Mon 9/78:10 am
SAV
- MKE
1 stop5h 28m
United Airlines
Deal found 7/4![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:45 am
MKE
- CAE
2 stops8h 33m
American Airlines
Sat 8/296:00 am
CAE
- MKE
1 stop6h 02m
American Airlines
Deal found 7/8![American Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:03 am
MKE
- HHH
1 stop4h 24m
Delta
Tue 10/64:10 pm
HHH
- MKE
1 stop6h 39m
Delta
Deal found 7/7![Delta logo]()
$330
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:00 am
MKE
- GSP
2 stops6h 55m
Southwest
Tue 8/111:20 pm
GSP
- MKE
2 stops8h 10m
Southwest
Deal found 7/6![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:19 pm
MKE
- CAE
1 stop7h 09m
United Airlines
Wed 9/26:25 am
CAE
- MKE
1 stop7h 13m
United Airlines
Deal found 7/3![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:40 am
MKE
- CAE
1 stop4h 34m
Delta
Sun 8/27:39 pm
CAE
- MKE
1 stop5h 17m
Delta
Deal found 7/3![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:45 am
MKE
- MYR
2 stops6h 25m
Southwest
Sun 8/237:30 am
MYR
- MKE
1 stop5h 40m
Southwest
Deal found 7/7![Southwest logo]()
$341
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:09 pm
MKE
- AGS
1 stop5h 39m
American Airlines
Sat 10/316:30 am
AGS
- MKE
1 stop4h 44m
American Airlines
Deal found 7/6![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am
MKE
- CAE
2 stops7h 06m
United Airlines
Sun 9/66:25 am
CAE
- MKE
1 stop4h 35m
United Airlines
Deal found 7/6![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:03 am
MKE
- CAE
1 stop6h 50m
Delta
Sun 8/167:47 pm
CAE
- MKE
1 stop5h 06m
Delta
Deal found 7/5![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:00 am
MKE
- GSP
1 stop4h 49m
American Airlines
Sun 8/99:27 am
GSP
- MKE
1 stop7h 07m
American Airlines
Deal found 7/3![American Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:35 am
MKE
- CLT
1 stop6h 05m
Southwest
Wed 9/91:30 pm
CLT
- MKE
2 stops8h 55m
Southwest
Deal found 7/7![Southwest logo]()
$353
Last-minute flights from Milwaukee to South CarolinaDiscover last-minute flight deals from Milwaukee to South Carolina. Data last updated July 8, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to South Carolina. Data last updated July 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:49 pm
MKE
- MYR
1 stop5h 21m
American Airlines
Tue 8/116:04 pm
MYR
- MKE
1 stop6h 55m
American Airlines
Deal found 7/8![American Airlines logo]()
$243
This Frontier deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Sat 8/159:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/5![Frontier logo]()
$279
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/129:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/4![Frontier logo]()
$258
This Booking.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Mon 8/179:43 pm
CLT
- MKE
1 stop14h 30m
Frontier
Deal found 7/3![Frontier logo]()
$270
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:40 am
MKE
- CLT
1 stop4h 05m
Southwest
Sat 8/227:55 am
CLT
- MKE
2 stops8h 50m
Southwest
Deal found 7/7![Southwest logo]()
$264
This Mytrip deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:10 pm
MKE
- CLT
1 stop18h 51m
Frontier
Sat 8/229:52 pm
CLT
- MKE
1 stop14h 21m
Frontier
Deal found 7/4![Frontier logo]()
$268
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:28 am
MKE
- MYR
1 stop3h 56m
American Airlines
Thu 8/205:15 pm
MYR
- MKE
1 stop5h 32m
American Airlines
Deal found 7/7![American Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:05 pm
MKE
- MYR
1 stop4h 15m
Southwest
Thu 8/201:55 pm
MYR
- MKE
2 stops8h 30m
Southwest
Deal found 7/7![Southwest logo]()
$270
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:00 am
MKE
- MYR
1 stop4h 10m
Southwest
Thu 8/2710:50 am
MYR
- MKE
1 stop5h 35m
Southwest
Deal found 7/6![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:00 am
MKE
- SAV
1 stop6h 35m
Southwest
Thu 8/2711:25 am
SAV
- MKE
1 stop5h 00m
Southwest
Deal found 7/6![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:45 am
MKE
- CAE
1 stop7h 01m
American Airlines
Sat 8/295:51 pm
CAE
- MKE
1 stop6h 08m
American Airlines
Deal found 7/8![American Airlines logo]()
$261
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:00 am
MKE
- CHS
1 stop4h 36m
United Airlines
Mon 8/3111:40 am
CHS
- MKE
1 stop5h 30m
United Airlines
Deal found 7/7![United Airlines logo]()
$249
One-way flights from Milwaukee to South CarolinaSearch for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
Search for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:09 am
MKE
- CLT
1 stop4h 08m
Delta
Deal found 7/7![Delta logo]()
$112
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:49 pm
MKE
- MYR
1 stop5h 21m
American Airlines
Deal found 7/7![American Airlines logo]()
$122
This Priceline deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Deal found 7/7![Frontier logo]()
$123
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:51 pm
MKE
- CHS
1 stop5h 00m
Delta
Deal found 7/8![Delta logo]()
$125
This Priceline deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Deal found 7/6![Frontier logo]()
$134
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:40 am
MKE
- CLT
2 stops10h 20m
Southwest
Deal found 7/8![Southwest logo]()
$135
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:20 am
MKE
- CHS
2 stops9h 55m
Southwest
Deal found 7/8![Southwest logo]()
$136
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:51 pm
MKE
- CHS
1 stop5h 00m
Delta
Deal found 7/8![Delta logo]()
$137
This Booking.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/812:10 pm
MKE
- CLT
1 stop27h 28m
Frontier
Deal found 7/6![Frontier logo]()
$140
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:55 am
MKE
- CLT
1 stop3h 40m
Southwest
Deal found 7/7![Southwest logo]()
$141
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:00 am
MKE
- CHS
2 stops8h 27m
United Airlines
Deal found 7/8![United Airlines logo]()
$142
This Priceline deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Deal found 7/4![Frontier logo]()
$144
Find flight deals from Milwaukee to South Carolina
Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated July 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (American Airlines) |
One-way from | $112 (Delta) |
Popular in | February |
Cheapest in | January |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Tue 9/8
6:40 am-11:55 am
1 stop4h 15m
Charlotte Douglas
Tue 9/22
8:05 am-11:05 am
1 stop4h 00m
$258
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Wed 8/19
2:05 pm-7:20 pm
1 stop4h 15m
Myrtle Beach Intl
Thu 8/20
1:55 pm-9:25 pm
2 stops8h 30m
$270
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Sat 9/5
8:35 am-2:25 pm
1 stop4h 50m
Charlotte Douglas
Thu 9/10
11:50 am-7:50 pm
2 stops9h 00m
$276
MilwaukeeSavannah
MKE - SAV
MKESAV
Milwaukee-Mitchell
Thu 8/20
12:30 pm-8:45 pm
1 stop7h 15m
Savannah/Hilton Head
Thu 8/27
4:10 pm-9:25 pm
2 stops6h 15m
$282
MilwaukeeHilton Head Island
MKE - HHH
MKEHHH
Milwaukee-Mitchell
Sat 11/14
6:14 am-2:19 pm
1 stop7h 05m
Hilton Head Island
Tue 11/17
2:51 pm-6:01 pm
1 stop4h 10m
$285
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Sat 8/29
6:15 am-7:00 pm
2 stops11h 45m
Myrtle Beach Intl
Sat 9/5
11:45 am-6:25 pm
2 stops7h 40m
$289
MilwaukeeHilton Head Island
MKE - HHH
MKEHHH
Milwaukee-Mitchell
Tue 8/4
10:22 am-3:32 pm
1 stop4h 10m
Hilton Head Island
Tue 8/11
12:15 pm-6:08 pm
2 stops6h 53m
$290
MilwaukeeGreenville
MKE - GSP
MKEGSP
Milwaukee-Mitchell
Thu 7/23
8:43 am-7:30 am
1 stop21h 47m
Greenville
Mon 7/27
8:20 am-7:58 am
1 stop24h 38m
$298
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Thu 9/3
8:20 am-4:27 pm
1 stop7h 07m
Columbia Metropolitan
Mon 9/7
5:51 pm-9:54 pm
1 stop5h 03m
$311
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Sun 8/2
5:45 am-11:14 am
1 stop4h 29m
Columbia Metropolitan
Sat 8/8
6:11 am-11:39 am
1 stop6h 28m
$315
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
MKE-CLT
MKE-HHH
MKE-GSP
MKE-MYR
MKE-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to South Carolina
MKE-USSC
MKE-CLT
MKE-HHH
MKE-GSP
MKE-MYR
What is the cheapest month to book a flight from Milwaukee to South Carolina?
Currently, March is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $100). Flying from Milwaukee to South Carolina in April is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Milwaukee to South Carolina?
How far ahead should I book a flight from Milwaukee to South Carolina?
The best time to book flights from Milwaukee to South Carolina is 70 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 8, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Milwaukee to South Carolina by cabin class
Find flights from Milwaukee to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Milwaukee and South Carolina flights
Browse other Milwaukee and South Carolina flight options. Last updated on July 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Milwaukee to South Carolina flights
Consider these flights traveling from Milwaukee to South Carolina.
Top 4 airlines flying from Milwaukee to South Carolina
Discover the top 4 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$375 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$373 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$290 | Average$424 | FlexibilityNo cancel fee | On-time63% |