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South Carolina

$89+ Cheap flights from Madison (MSN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — CHS
Mar 19 — Mar 261
Thu 3/19
Thu 3/26
1 adult, Economy
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Cheap flight deals from Madison to South Carolina

Cheapest flights from Madison to South Carolina
Explore the most affordable flight options available from Madison to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.

This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:44 pm
MSN
-
CHS
1 stop5h 41m
United Airlines
Tue 4/284:55 pm
CHS
-
MSN
1 stop5h 21m
United Airlines
Deal found 2/16$251
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:00 am
MSN
-
GSP
1 stop8h 39m
American Airlines
Sat 4/257:00 am
GSP
-
MSN
1 stop6h 35m
American Airlines
Deal found 2/14$251
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:00 am
MSN
-
CHS
1 stop7h 18m
American Airlines
Mon 3/238:19 pm
CHS
-
MSN
1 stop4h 16m
American Airlines
Deal found 2/14$260
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/113:08 pm
MSN
-
GSP
1 stop5h 18m
Delta
Mon 3/166:14 pm
GSP
-
MSN
1 stop3h 52m
Delta
Deal found 2/15$260
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/139:54 am
MSN
-
CLT
1 stop22h 24m
Multiple Airlines
Sat 5/168:05 pm
CLT
-
MSN
2 stops37h 20m
Multiple Airlines
Deal found 2/17$263
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/73:53 pm
MSN
-
CHS
1 stop4h 04m
United Airlines
Tue 3/108:15 am
CHS
-
MSN
1 stop4h 23m
United Airlines
Deal found 2/16$265
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:30 am
MSN
-
GSP
2 stops6h 47m
United Airlines
Tue 3/245:32 pm
GSP
-
MSN
1 stop6h 00m
United Airlines
Deal found 2/17$265
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:43 am
MSN
-
CHS
1 stop7h 20m
Delta
Wed 6/107:10 am
CHS
-
MSN
1 stop6h 44m
Delta
Deal found 2/17$269
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:01 am
MSN
-
HHH
1 stop8h 13m
American Airlines
Wed 5/63:44 pm
HHH
-
MSN
1 stop7h 24m
American Airlines
Deal found 2/14$269
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:15 pm
MSN
-
SAV
1 stop5h 41m
Delta
Tue 4/145:35 am
SAV
-
MSN
1 stop5h 57m
Delta
Deal found 2/17$269
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:53 pm
MSN
-
GSP
1 stop3h 54m
United Airlines
Sat 4/185:36 pm
GSP
-
MSN
1 stop4h 40m
United Airlines
Deal found 2/17$269
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:20 am
MSN
-
MYR
1 stop6h 57m
American Airlines
Fri 5/89:14 am
MYR
-
MSN
1 stop4h 16m
American Airlines
Deal found 2/14$269

Find flight deals from Madison to South Carolina

Keep the following information in mind while searching for Madison to South Carolina flight deals. Data was last updated February 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$89
(Trip.com)

Popular in

March

Cheapest in

January

Average price

$357
Provider with most accurate pricing for Madison Truax Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madison Truax Field-Myrtle Beach Intl flights.
Search Deals
From Madison Truax Field to South Carolina
Search Deals
One-way flight from Madison Truax Field to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madison to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Madison to South Carolina that are best for you.

Fly from

Madison

Fly to

South Carolina

Route

Depart

Return

Price

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Wed 4/22

11:44 am-7:04 pm

1 stop6h 20m

Charleston

Tue 4/28

5:11 am-11:01 am

1 stop6h 50m

$251

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Wed 4/15

8:05 am-5:39 pm

1 stop8h 34m

Greenville

Sat 4/25

7:31 am-2:30 pm

1 stop7h 59m

$251

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Wed 4/22

2:44 pm-11:59 pm

2 stops8h 15m

Charleston

Tue 4/28

4:55 pm-9:16 pm

1 stop5h 21m

$256

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Wed 3/11

3:08 pm-9:26 pm

1 stop5h 18m

Greenville

Mon 3/16

6:14 pm-9:06 pm

1 stop3h 52m

$260

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Tue 3/10

2:50 pm-9:16 pm

1 stop5h 26m

Charleston

Mon 3/16

6:45 pm-10:32 pm

1 stop4h 47m

$260

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Sat 4/11

5:15 pm-11:54 pm

1 stop5h 39m

Greenville

Sat 4/18

7:30 am-10:28 am

1 stop3h 58m

$260

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Tue 5/19

8:10 am-1:51 pm

1 stop4h 41m

Charleston

Tue 5/26

6:00 am-11:48 am

1 stop6h 48m

$265

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Sat 6/6

5:26 pm-10:56 pm

1 stop4h 30m

Charleston

Wed 6/10

7:10 am-12:54 pm

1 stop6h 44m

$269

MadisonHilton Head Island

MSN - HHH

MSNHHH

Madison Truax Field

Wed 4/29

6:01 am-3:14 pm

1 stop8h 13m

Hilton Head Island

Wed 5/6

3:44 pm-10:08 pm

1 stop7h 24m

$269

MadisonSavannah

MSN - SAV

MSNSAV

Madison Truax Field

Sat 4/11

5:15 pm-11:56 pm

1 stop5h 41m

Savannah/Hilton Head

Tue 4/14

5:35 am-10:32 am

1 stop5h 57m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 60 results
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Best time to book a flight from Madison to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madison with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madison to South Carolina

What is the cheapest month to book a flight from Madison to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Madison to South Carolina (average of $118). Flying from Madison to South Carolina in February is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSN to SC?

Find hourly flight availability from Madison to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 17, 2026.

A simple way to save on the total cost of your ticket is to fly from Madison to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 60% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Madison to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Madison to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Madison to South Carolina flight should consider departing on Saturday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 17, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Madison to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,206 reviews

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,206 reviews
Delta
7.9
Good
8,206 reviews

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,308 reviews
Delta
7.9
Good
8,206 reviews

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,294 reviews
Delta
7.9
Good
8,206 reviews

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Madison to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madison to South Carolina?

    Most people fly from Madison Truax Field (MSN) if they book a flight from Madison to South Carolina. Madison Truax Field is conveniently located just 5.4 mi from Madison’s city center.

  • How long is the flight from Madison to South Carolina?

    For as low as $260, American Airlines can have you in South Carolina from Madison in 5h 18m. The distance from Madison to South Carolina is about 684 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madison to South Carolina?

    The most popular flight routes from Madison to South Carolina are Madison Truax Field - Charleston, Madison Truax Field - Charlotte Douglas and Madison Truax Field - Myrtle Beach Intl.

  • Can I find deals for flights from Madison to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madison to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madison to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madison to South Carolina.

  • Can I find deals for business class flights from Madison to South Carolina?

    Yes. Cheapflights offers flight deals from Madison to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madison to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Madison to South Carolina (average of $118). Flying from Madison to South Carolina in February is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Madison to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Madison to South Carolina

Discover the top 3 airlines that operate flights from Madison to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$395FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$215Average$340FlexibilityNo cancel feeOn-time69%

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