$127+ Cheap flights from Madison (MSN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — CHS
May 8 — May 151
Round-trip
1 adult, Economy
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Find cheap flights from Madison to South Carolina with Cheapflights
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Cheapest flights from Madison to South CarolinaExplore the most affordable flight options available from Madison to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.
Explore the most affordable flight options available from Madison to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.
This Trip.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:37 pm
MSN
- CLT
1 stop25h 58m
Frontier
Sat 4/185:51 pm
CLT
- MSN
1 stop21h 01m
Frontier
Deal found 4/5![Frontier logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:00 pm
MSN
- SAV
1 stop4h 58m
American Airlines
Tue 7/147:45 am
SAV
- MSN
1 stop5h 21m
American Airlines
Deal found 4/5![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:05 pm
MSN
- GSP
1 stop5h 33m
American Airlines
Sat 5/235:25 pm
GSP
- MSN
1 stop6h 42m
American Airlines
Deal found 4/8![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:50 pm
MSN
- SAV
2 stops8h 09m
American Airlines
Wed 6/39:06 am
SAV
- MSN
1 stop7h 58m
American Airlines
Deal found 4/4![American Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:29 pm
MSN
- SAV
1 stop5h 11m
Delta
Wed 5/135:05 pm
SAV
- MSN
1 stop6h 39m
Delta
Deal found 4/6![Delta logo]()
$271
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:40 pm
MSN
- CHS
1 stop7h 20m
American Airlines
Wed 6/38:25 am
CHS
- MSN
1 stop6h 45m
American Airlines
Deal found 4/7![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:08 pm
MSN
- SAV
1 stop5h 45m
American Airlines
Sat 5/235:09 am
SAV
- MSN
2 stops7h 54m
American Airlines
Deal found 4/8![American Airlines logo]()
$276
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:30 am
MSN
- CHS
2 stops6h 57m
United Airlines
Wed 7/156:00 am
CHS
- MSN
1 stop4h 59m
United Airlines
Deal found 4/5![United Airlines logo]()
$280
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:30 pm
MSN
- SAV
2 stops8h 29m
United Airlines
Tue 5/2611:30 am
SAV
- MSN
1 stop4h 27m
United Airlines
Deal found 4/4![United Airlines logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:30 am
MSN
- CHS
2 stops6h 55m
United Airlines
Sat 9/122:51 pm
CHS
- MSN
2 stops7h 14m
United Airlines
Deal found 4/5![United Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:25 pm
MSN
- SAV
1 stop7h 36m
American Airlines
Sat 6/137:09 am
SAV
- MSN
1 stop5h 54m
American Airlines
Deal found 4/8![American Airlines logo]()
$286
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:07 am
MSN
- CHS
1 stop6h 52m
Delta
Tue 7/147:00 am
CHS
- MSN
1 stop8h 17m
Delta
Deal found 4/5![Delta logo]()
$287
Best flights from Madison to South CarolinaDiscover carefully curated flight deals from Madison to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 8, 2026.
Discover carefully curated flight deals from Madison to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 8, 2026.
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:00 am
MSN
- SAV
1 stop4h 23m
United Airlines
Tue 8/412:10 pm
SAV
- MSN
2 stops10h 04m
United Airlines
Deal found 4/4![United Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:23 pm
MSN
- CHS
1 stop6h 36m
American Airlines
Wed 6/37:51 pm
CHS
- MSN
1 stop5h 06m
American Airlines
Deal found 4/8![American Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:32 am
MSN
- CHS
1 stop7h 26m
Delta
Wed 7/156:15 am
CHS
- MSN
1 stop5h 07m
Delta
Deal found 4/5![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
MSN
- GSP
1 stop13h 38m
Multiple Airlines
Sun 5/109:33 am
GSP
- MSN
2 stops23h 52m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:11 am
MSN
- SAV
1 stop5h 39m
Delta
Mon 9/76:50 pm
SAV
- MSN
1 stop4h 45m
Delta
Deal found 4/5![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:00 am
MSN
- SAV
1 stop4h 23m
United Airlines
Mon 6/2211:30 am
SAV
- MSN
1 stop4h 27m
United Airlines
Deal found 4/7![United Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 am
MSN
- MYR
2 stops9h 58m
American Airlines
Tue 6/94:17 pm
MYR
- MSN
2 stops8h 40m
American Airlines
Deal found 4/8![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:45 pm
MSN
- CHS
1 stop7h 19m
Delta
Wed 9/236:30 am
CHS
- MSN
1 stop4h 41m
Delta
Deal found 4/7![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:45 am
MSN
- HHH
1 stop4h 52m
American Airlines
Fri 5/12:58 pm
HHH
- MSN
2 stops8h 12m
American Airlines
Deal found 4/5![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:00 am
MSN
- GSP
1 stop4h 11m
United Airlines
Tue 6/96:00 am
GSP
- MSN
1 stop6h 48m
United Airlines
Deal found 4/4![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:20 pm
MSN
- GSP
1 stop5h 53m
Delta
Wed 5/277:20 am
GSP
- MSN
1 stop6h 21m
Delta
Deal found 4/4![Delta logo]()
$312
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
MSN
- HHH
1 stop6h 40m
American Airlines
Fri 5/156:39 pm
HHH
- MSN
1 stop6h 15m
American Airlines
Deal found 4/4![American Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:35 pm
MSN
- CHS
1 stop7h 01m
Delta
Sun 7/55:10 am
CHS
- MSN
1 stop6h 09m
Delta
Deal found 4/4![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:53 pm
MSN
- SAV
2 stops7h 06m
United Airlines
Sat 4/255:45 am
SAV
- MSN
2 stops6h 53m
United Airlines
Deal found 4/6![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:00 am
MSN
- HHH
1 stop6h 13m
American Airlines
Mon 6/15:21 pm
HHH
- MSN
1 stop7h 38m
American Airlines
Deal found 4/8![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
MSN
- SAV
2 stops8h 43m
United Airlines
Tue 7/1412:10 pm
SAV
- MSN
2 stops11h 49m
United Airlines
Deal found 4/4![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:29 pm
MSN
- MYR
1 stop5h 29m
Delta
Mon 6/16:00 am
MYR
- MSN
1 stop5h 16m
Delta
Deal found 4/5![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:00 am
MSN
- SAV
1 stop4h 16m
United Airlines
Thu 4/307:04 pm
SAV
- MSN
1 stop4h 50m
United Airlines
Deal found 4/7![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
MSN
- HHH
1 stop6h 40m
American Airlines
Sat 5/162:54 pm
HHH
- MSN
2 stops9h 47m
American Airlines
Deal found 4/4![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:04 pm
MSN
- MYR
1 stop6h 10m
Delta
Sat 4/256:00 am
MYR
- MSN
1 stop5h 32m
Delta
Deal found 4/4![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:10 am
MSN
- CHS
1 stop4h 45m
United Airlines
Wed 9/26:43 pm
CHS
- MSN
1 stop4h 59m
United Airlines
Deal found 4/8![United Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:29 pm
MSN
- AGS
1 stop6h 27m
American Airlines
Tue 5/196:20 am
AGS
- MSN
1 stop5h 33m
American Airlines
Deal found 4/5![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:30 am
MSN
- SAV
1 stop6h 41m
United Airlines
Tue 9/13:14 pm
SAV
- MSN
1 stop6h 51m
United Airlines
Deal found 4/6![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:00 am
MSN
- SAV
1 stop6h 30m
Delta
Sun 8/307:00 am
SAV
- MSN
1 stop4h 11m
Delta
Deal found 4/8![Delta logo]()
$378
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:08 pm
MSN
- AGS
1 stop5h 50m
American Airlines
Wed 5/276:00 am
AGS
- MSN
1 stop7h 55m
American Airlines
Deal found 4/6![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 am
MSN
- SAV
2 stops7h 13m
United Airlines
Sun 7/197:00 pm
SAV
- MSN
1 stop6h 22m
United Airlines
Deal found 4/7![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:29 pm
MSN
- AGS
1 stop5h 23m
Delta
Tue 5/197:50 pm
AGS
- MSN
1 stop3h 54m
Delta
Deal found 4/4![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:03 pm
MSN
- AGS
2 stops8h 56m
American Airlines
Sat 5/306:27 pm
AGS
- MSN
1 stop6h 42m
American Airlines
Deal found 4/7![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:29 pm
MSN
- AGS
2 stops6h 58m
Delta
Wed 5/275:42 am
AGS
- MSN
1 stop5h 34m
Delta
Deal found 4/8![Delta logo]()
$384
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:46 pm
MSN
- CLT
2 stops7h 12m
United Airlines
Tue 7/710:24 am
CLT
- MSN
1 stop5h 41m
United Airlines
Deal found 4/6![United Airlines logo]()
$395
Last-minute flights from Madison to South CarolinaDiscover last-minute flight deals from Madison to South Carolina. Data last updated April 8, 2026 and is based on user searches.
Discover last-minute flight deals from Madison to South Carolina. Data last updated April 8, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:37 pm
MSN
- CLT
1 stop25h 58m
Frontier
Sat 4/185:51 pm
CLT
- MSN
1 stop21h 01m
Frontier
Deal found 4/5![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:36 pm
MSN
- CLT
1 stop11h 29m
Multiple Airlines
Mon 4/2710:39 pm
CLT
- MSN
2 stops35h 29m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:12 pm
MSN
- CHS
1 stop6h 23m
American Airlines
Tue 5/126:32 pm
CHS
- MSN
1 stop4h 39m
American Airlines
Deal found 4/8![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:29 pm
MSN
- SAV
1 stop5h 11m
Delta
Wed 5/135:05 pm
SAV
- MSN
1 stop6h 39m
Delta
Deal found 4/6![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:29 pm
MSN
- SAV
1 stop5h 11m
Delta
Fri 5/155:05 pm
SAV
- MSN
1 stop6h 39m
Delta
Deal found 4/6![Delta logo]()
$296
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:08 pm
MSN
- SAV
1 stop5h 45m
American Airlines
Sat 5/235:09 am
SAV
- MSN
2 stops7h 54m
American Airlines
Deal found 4/8![American Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:05 pm
MSN
- GSP
1 stop5h 33m
American Airlines
Sat 5/235:25 pm
GSP
- MSN
1 stop6h 42m
American Airlines
Deal found 4/8![American Airlines logo]()
$261
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:30 pm
MSN
- SAV
2 stops8h 29m
United Airlines
Tue 5/2611:30 am
SAV
- MSN
1 stop4h 27m
United Airlines
Deal found 4/4![United Airlines logo]()
$282
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:33 am
MSN
- GSP
1 stop4h 28m
American Airlines
Wed 5/206:28 pm
GSP
- MSN
1 stop5h 59m
American Airlines
Deal found 4/8![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:40 pm
MSN
- CHS
1 stop7h 20m
American Airlines
Wed 6/38:25 am
CHS
- MSN
1 stop6h 45m
American Airlines
Deal found 4/7![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:18 am
MSN
- SAV
1 stop8h 35m
American Airlines
Wed 6/37:08 am
SAV
- MSN
1 stop5h 55m
American Airlines
Deal found 4/4![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:25 pm
MSN
- SAV
1 stop7h 36m
American Airlines
Sat 6/137:09 am
SAV
- MSN
1 stop5h 54m
American Airlines
Deal found 4/8![American Airlines logo]()
$286
One-way flights from Madison to South CarolinaSearch for one-way flight options from Madison to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 8, 2026.
Search for one-way flight options from Madison to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:36 pm
MSN
- CLT
1 stop12h 33m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
MSN
- CLT
1 stop24h 08m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
MSN
- CLT
1 stop17h 07m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:55 pm
MSN
- CHS
1 stop11h 43m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:36 pm
MSN
- CLT
1 stop12h 33m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:50 pm
MSN
- CLT
2 stops40h 15m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:50 pm
MSN
- CLT
2 stops44h 53m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
MSN
- CHS
1 stop13h 33m
Breeze Airways
Deal found 4/8![Breeze Airways logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:54 am
MSN
- CLT
2 stops25h 11m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:50 pm
MSN
- CLT
2 stops45h 54m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:05 pm
MSN
- CLT
1 stop21h 38m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:55 pm
MSN
- CHS
1 stop11h 43m
Breeze Airways
Deal found 4/8![Breeze Airways logo]()
$162
Find flight deals from Madison to South Carolina
Keep the following information in mind while searching for Madison to South Carolina flight deals. Data was last updated April 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (American Airlines) |
One-way from | $127 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $338 |
Cheapflights Fare Finder
Customize your flight search to find flights from Madison to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Madison to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadisonSavannah
MSN - SAV
MSNSAV
Madison Truax Field
Sat 8/1
5:00 am-10:23 am
1 stop4h 23m
Savannah/Hilton Head
Tue 8/4
12:10 pm-9:14 pm
2 stops10h 04m
$266
MadisonCharleston
MSN - CHS
MSNCHS
Madison Truax Field
Thu 5/28
4:23 pm-11:59 pm
1 stop6h 36m
Charleston
Wed 6/3
7:51 pm-11:57 pm
1 stop5h 06m
$275
MadisonCharleston
MSN - CHS
MSNCHS
Madison Truax Field
Tue 7/7
9:32 am-5:58 pm
1 stop7h 26m
Charleston
Wed 7/15
6:15 am-10:22 am
1 stop5h 07m
$287
MadisonSavannah
MSN - SAV
MSNSAV
Madison Truax Field
Wed 9/2
11:11 am-5:50 pm
1 stop5h 39m
Savannah/Hilton Head
Mon 9/7
6:50 pm-10:35 pm
1 stop4h 45m
$296
Quickest round-trip
MadisonSavannah
MSN - SAV
MSNSAV
Madison Truax Field
Wed 6/17
5:00 am-10:23 am
1 stop4h 23m
Savannah/Hilton Head
Mon 6/22
11:30 am-2:57 pm
1 stop4h 27m
$306
MadisonCharleston
MSN - CHS
MSNCHS
Madison Truax Field
Wed 9/16
1:45 pm-10:04 pm
1 stop7h 19m
Charleston
Wed 9/23
6:30 am-10:11 am
1 stop4h 41m
$307
MadisonGreenville
MSN - GSP
MSNGSP
Madison Truax Field
Sat 5/23
1:20 pm-8:13 pm
1 stop5h 53m
Greenville
Wed 5/27
7:20 am-12:41 pm
1 stop6h 21m
$312
MadisonCharleston
MSN - CHS
MSNCHS
Madison Truax Field
Thu 7/2
4:35 pm-12:36 am
1 stop7h 01m
Charleston
Sun 7/5
5:10 am-10:19 am
1 stop6h 09m
$317
MadisonMyrtle Beach
MSN - MYR
MSNMYR
Madison Truax Field
Fri 5/29
5:29 pm-11:58 pm
1 stop5h 29m
Myrtle Beach Intl
Mon 6/1
6:00 am-10:16 am
1 stop5h 16m
$329
MadisonMyrtle Beach
MSN - MYR
MSNMYR
Madison Truax Field
Tue 6/2
5:00 am-3:58 pm
2 stops9h 58m
Myrtle Beach Intl
Tue 6/9
4:17 pm-11:57 pm
2 stops8h 40m
$333
Showing 1-10 of 58 resultsSorted by cheapest first
Best time to book a flight from Madison to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madison with our price prediction graph.
MSN-CLT
MSN-SAV
MSN-GSP
MSN-CHS
MSN-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madison to South Carolina
MSN-USSC
MSN-CLT
MSN-SAV
MSN-GSP
MSN-CHS
What is the cheapest month to book a flight from Madison to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Madison to South Carolina (average of $120). Flying from Madison to South Carolina in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSN to SC?
Find hourly flight availability from Madison to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 8, 2026.
A simple way to save on the total cost of your ticket is to fly from Madison to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 60% on your trip compared to booking a flight in the afternoon.
What is the cheapest day to fly from Madison to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Madison to South Carolina. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their Madison to South Carolina flight should consider departing on Saturday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Madison to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 8, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Madison to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.9
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Madison to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Madison to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Madison and South Carolina flights
Browse other Madison and South Carolina flight options. Last updated on April 8, 2026.
Popular flight searches
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Madison to South Carolina flights
Consider these flights traveling from Madison to South Carolina.
Top 3 airlines flying from Madison to South Carolina
Discover the top 3 airlines that operate flights from Madison to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$387 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$353 | FlexibilityNo cancel fee | On-time69% |