South Carolina

$126+ Cheap flights from Madison (MSN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — CHS
Jan 7 — Jan 141
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Cheap flight deals from Madison to South Carolina

Cheapest flights from Madison to South Carolina
Explore the most affordable flight options available from Madison to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:45 amMSN - CHS
1 stop3h 58mAmerican Airlines
Tue 12/306:44 amCHS - MSN
1 stop4h 24mAmerican Airlines
Deal found 12/7$294
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:15 pmMSN - CHS
1 stop6h 11mAmerican Airlines
Sat 1/36:44 amCHS - MSN
1 stop4h 24mAmerican Airlines
Deal found 12/8$304
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/164:02 pmMSN - CHS
1 stop4h 42mAmerican Airlines
Mon 12/226:27 pmCHS - MSN
1 stop6h 32mAmerican Airlines
Deal found 12/7$309
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:15 amMSN - SAV
1 stop5h 12mUnited Airlines
Thu 12/254:55 pmSAV - MSN
1 stop6h 35mUnited Airlines
Deal found 12/7$309
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:40 amMSN - CHS
2 stops7h 42mUnited Airlines
Tue 12/306:05 amCHS - MSN
1 stop6h 43mUnited Airlines
Deal found 12/7$313
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:10 amMSN - CLT
1 stop4h 09mAmerican Airlines
Sat 1/38:59 amCLT - MSN
Nonstop2h 09mAmerican Airlines
Deal found 12/7$347
This Delta deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amMSN - CHS
1 stop7h 16mDelta
Tue 12/165:00 pmCHS - MSN
1 stop6h 26mDelta
Deal found 12/6$354
This Delta deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amMSN - SAV
1 stop7h 22mDelta
Mon 12/157:10 pmSAV - MSN
1 stop4h 16mDelta
Deal found 12/8$354
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:02 pmMSN - CHS
2 stops6h 11mAmerican Airlines
Tue 12/165:05 pmCHS - MSN
1 stop5h 51mAmerican Airlines
Deal found 12/6$359
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:00 amMSN - SAV
2 stops8h 13mAmerican Airlines
Mon 12/1511:12 amSAV - MSN
1 stop5h 11mAmerican Airlines
Deal found 12/8$359
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:18 pmMSN - MYR
1 stop5h 31mAmerican Airlines
Mon 12/157:34 pmMYR - MSN
1 stop5h 06mAmerican Airlines
Deal found 12/8$364
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 amMSN - CLT
Nonstop2h 19mAmerican Airlines
Wed 12/318:59 amCLT - MSN
Nonstop2h 09mAmerican Airlines
Deal found 12/6$371

Find flight deals from Madison to South Carolina

Keep the following information in mind while searching for Madison to South Carolina flight deals. Data was last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$126
(Delta)

Popular in

June

Cheapest in

September

Average price

$362
Provider with most accurate pricing for Madison Truax Field-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Madison Truax Field-Myrtle Beach Intl flights.
From Madison Truax Field to South Carolina
One-way flight from Madison Truax Field to South Carolina
Highest demand for flights based on searches. 11% potential increase in price ($46 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madison to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Madison to South Carolina that are best for you.

Fly from

Madison

Fly to

South Carolina

Route

Depart

Return

Price

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Fri 1/23

6:30 am-12:32 pm

1 stop5h 02m

Charleston

Sun 1/25

7:01 pm-11:44 pm

1 stop5h 43m

$249

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Wed 2/18

8:04 am-4:20 pm

1 stop7h 16m

Charleston

Sat 2/21

6:35 am-10:10 am

1 stop4h 35m

$249

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Tue 2/17

11:31 am-5:38 pm

1 stop5h 07m

Charleston

Tue 2/24

11:39 am-7:13 pm

1 stop8h 34m

$249

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Sat 2/21

6:30 am-1:52 pm

1 stop6h 22m

Charleston

Wed 2/25

1:11 pm-7:08 pm

1 stop6h 57m

$249

MadisonSavannah

MSN - SAV

MSNSAV

Madison Truax Field

Fri 1/16

6:30 am-2:07 pm

1 stop6h 37m

Savannah/Hilton Head

Wed 1/21

11:48 am-3:44 pm

1 stop4h 56m

$249

MadisonSavannah

MSN - SAV

MSNSAV

Madison Truax Field

Wed 1/14

7:20 am-3:12 pm

1 stop6h 52m

Savannah/Hilton Head

Tue 1/20

5:21 pm-11:47 pm

1 stop7h 26m

$249

MadisonCharleston

MSN - CHS

MSNCHS

Madison Truax Field

Wed 2/4

12:38 pm-8:02 pm

1 stop6h 24m

Charleston

Mon 2/9

4:41 pm-9:05 pm

1 stop5h 24m

$249

MadisonSavannah

MSN - SAV

MSNSAV

Madison Truax Field

Thu 2/5

3:25 pm-10:33 pm

1 stop6h 08m

Savannah/Hilton Head

Tue 2/10

5:30 am-10:28 am

1 stop5h 58m

$249

MadisonMyrtle Beach

MSN - MYR

MSNMYR

Madison Truax Field

Fri 2/6

6:00 am-11:44 am

1 stop4h 44m

Myrtle Beach Intl

Tue 2/10

7:19 pm-11:47 pm

1 stop5h 28m

$249

MadisonMyrtle Beach

MSN - MYR

MSNMYR

Madison Truax Field

Wed 2/4

5:06 pm-11:41 pm

1 stop5h 35m

Myrtle Beach Intl

Tue 2/10

12:25 pm-7:15 pm

1 stop7h 50m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 56 results
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Best time to book a flight from Madison to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madison with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madison to South Carolina

What is the cheapest month to book a flight from Madison to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Madison to South Carolina (average of $118). Flying from Madison to South Carolina in December is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSN to SC?

Find hourly flight availability from Madison to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

A simple way to save on the total cost of your ticket is to fly from Madison to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 65% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Madison to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Madison to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Madison to South Carolina flight should consider departing on Saturday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 8, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Madison to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Comfort

7.9

Food

7.3

Crew

8.5

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Comfort

7.9

Food

7.3

Crew

8.5

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Comfort

7.9

Food

7.3

Crew

8.5

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Comfort

7.9

Food

7.3

Crew

8.5

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Madison to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Madison to South Carolina?

    Most people fly from Madison Truax Field (MSN) if they book a flight from Madison to South Carolina. Madison Truax Field is conveniently located just 5.4 mi from Madison’s city center.

  • How long is the flight from Madison to South Carolina?

    For as low as $249, United Airlines can have you in South Carolina from Madison in 5h 02m. The distance from Madison to South Carolina is about 868 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madison to South Carolina?

  • Can I find deals for flights from Madison to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madison to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madison to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madison to South Carolina.

  • Can I find deals for business class flights from Madison to South Carolina?

    Yes. Cheapflights offers flight deals from Madison to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madison to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Madison to South Carolina (average of $118). Flying from Madison to South Carolina in December is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Madison to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Madison to South Carolina

Discover the top 3 airlines that operate flights from Madison to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$334FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$400FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$342FlexibilityNo cancel feeOn-time69%

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