HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$102+ Cheap flights from Irvine, CA to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — CHS
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Irvine to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Irvine to South Carolina

Cheapest flights from Irvine to South Carolina
Explore the most affordable flight options available from Irvine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:11 pm
LAX
-
CLT
2 stops22h 43m
Frontier
Tue 4/217:49 pm
CLT
-
LAX
1 stop22h 31m
Frontier
Deal found 3/14$234
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:21 pm
LAX
-
CLT
1 stop9h 51m
Frontier
Sat 5/301:00 pm
CLT
-
LAX
1 stop12h 47m
Frontier
Deal found 3/16$235
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:54 pm
LAX
-
GSP
Nonstop4h 46m
Breeze Airways
Mon 5/1110:03 am
GSP
-
LAX
Nonstop5h 06m
Breeze Airways
Deal found 3/13$237
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:11 pm
LAX
-
CLT
2 stops11h 54m
Frontier
Sat 4/255:51 pm
CLT
-
LAX
1 stop8h 23m
Frontier
Deal found 3/14$237
This Expedia deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:51 pm
LAX
-
CLT
1 stop9h 06m
Multiple Airlines
Fri 4/101:20 pm
CLT
-
LAX
1 stop13h 36m
Multiple Airlines
Deal found 3/13$238
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:11 pm
LAX
-
CLT
2 stops13h 07m
Frontier
Tue 4/217:49 pm
CLT
-
LAX
1 stop22h 31m
Frontier
Deal found 3/13$239
This Frontier deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:59 pm
LAX
-
CLT
1 stop12h 46m
Frontier
Sat 4/255:51 pm
CLT
-
LAX
1 stop8h 23m
Frontier
Deal found 3/14$241
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:36 pm
LAX
-
CLT
1 stop12h 48m
Frontier
Sun 4/268:17 pm
CLT
-
LAX
2 stops46h 58m
Frontier
Deal found 3/16$242
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:15 am
LAX
-
CLT
1 stop8h 39m
Frontier
Mon 4/2010:39 pm
CLT
-
LAX
2 stops20h 36m
Frontier
Deal found 3/16$243
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:15 am
LAX
-
CLT
1 stop7h 41m
Multiple Airlines
Tue 4/219:32 pm
CLT
-
LAX
2 stops16h 52m
Multiple Airlines
Deal found 3/15$244
This Expedia deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:51 pm
LAX
-
CLT
1 stop9h 06m
Frontier
Tue 4/1410:00 am
CLT
-
LAX
1 stop16h 14m
Frontier
Deal found 3/13$245
This CheapOair deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:04 pm
LAX
-
CLT
1 stop16h 31m
Frontier
Fri 4/246:30 pm
CLT
-
LAX
1 stop19h 59m
Frontier
Deal found 3/16$246

Find flight deals from Irvine to South Carolina

Keep the following information in mind while searching for Irvine to South Carolina flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$234
(Kiwi.com)

One-way from

$102
(Booking.com)

Popular in

November

Cheapest in

August

Average price

$466
Provider with most accurate pricing for Los Angeles Los Angeles-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles Los Angeles-Myrtle Beach Intl flights.
Search Deals
From Irvine to South Carolina
Search Deals
One-way flight from Irvine to South Carolina
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($113 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Irvine to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Los AngelesCharleston

LAX - CHS

LAXCHS

Los Angeles Los Angeles

Sat 5/9

12:23 pm-8:24 pm

Nonstop5h 01m

Charleston

Fri 5/15

5:47 pm-9:50 pm

1 stop7h 03m

$313

Los AngelesMyrtle Beach

LAX - MYR

LAXMYR

Los Angeles Los Angeles

Fri 5/1

11:00 pm-3:50 pm

1 stop13h 50m

Myrtle Beach Intl

Sun 5/10

9:50 pm-9:03 am

2 stops38h 13m

$323

Los AngelesMyrtle Beach

LAX - MYR

LAXMYR

Los Angeles Los Angeles

Sat 4/18

11:59 pm-10:18 am

1 stop7h 19m

Myrtle Beach Intl

Sat 5/2

3:14 pm-10:35 pm

1 stop10h 21m

$331

Los AngelesMyrtle Beach

LAX - MYR

LAXMYR

Los Angeles Los Angeles

Fri 4/10

12:15 am-10:18 am

1 stop7h 03m

Myrtle Beach Intl

Sat 4/18

11:00 am-6:39 pm

1 stop10h 39m

$347

Los AngelesCharleston

LAX - CHS

LAXCHS

Los Angeles Los Angeles

Sat 5/9

11:39 pm-10:51 am

1 stop8h 12m

Charleston

Wed 5/13

5:26 pm-10:59 pm

1 stop8h 33m

$348

Los AngelesMyrtle Beach

LAX - MYR

LAXMYR

Los Angeles Los Angeles

Sat 5/9

6:00 am-4:07 pm

1 stop7h 07m

Myrtle Beach Intl

Wed 5/13

3:21 pm-9:31 pm

1 stop9h 10m

$351

Los AngelesSavannah

LAX - SAV

LAXSAV

Los Angeles Los Angeles

Fri 4/17

8:40 pm-9:55 am

1 stop10h 15m

Savannah/Hilton Head

Tue 4/21

10:45 am-5:09 pm

1 stop9h 24m

$361

Los AngelesHilton Head Island

LAX - HHH

LAXHHH

Los Angeles Los Angeles

Mon 4/6

10:02 pm-10:47 am

1 stop9h 45m

Hilton Head Island

Mon 4/13

5:04 pm-12:41 am

1 stop10h 37m

$369

Los AngelesCharlotte

LAX - CLT

LAXCLT

Los Angeles Los Angeles

Fri 5/22

10:55 pm-8:56 am

1 stop7h 01m

Charlotte Douglas

Tue 5/26

2:38 pm-8:57 pm

1 stop9h 19m

$373

Los AngelesCharleston

LAX - CHS

LAXCHS

Los Angeles Los Angeles

Wed 5/13

7:30 am-8:00 pm

2 stops9h 30m

Charleston

Wed 5/20

7:15 pm-11:40 pm

1 stop7h 25m

$382

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Irvine to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to South Carolina

What is the cheapest month to book a flight from Irvine to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Irvine to South Carolina (average of $112). Flying from Irvine to South Carolina in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to SC?

Find hourly flight availability from Irvine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 24% on flights from Irvine to South Carolina by exploring options for tickets in the morning.

What is the cheapest day to fly from Irvine to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Irvine to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Irvine to South Carolina flight should consider departing on Friday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Irvine to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 17, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Irvine to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Food

6.6

Overall

8.1

Boarding

8.3

Entertainment

6.6

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Food

6.6

Overall

8.1

Boarding

8.3

Entertainment

6.6

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Southwest
8.0
Very good
4,320 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Food

6.6

Overall

8.1

Boarding

8.3

Entertainment

6.6

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,288 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Food

6.6

Overall

8.1

Boarding

8.3

Entertainment

6.6

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
United Airlines
7.4
Good
9,431 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Food

6.6

Overall

8.1

Boarding

8.3

Entertainment

6.6

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.1
Good
11,466 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Food

6.6

Overall

8.1

Boarding

8.3

Entertainment

6.6

Crew

8.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Irvine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Irvine to South Carolina flight route?

    This flight path from Irvine to South Carolina was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Irvine to South Carolina?

    There are many flights that can get you from Irvine to South Carolina in 5h 01m. Fly via Breeze Airways, United Airlines, or Delta to get the fastest option. The distance between Irvine and South Carolina is about 2200 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Irvine to South Carolina one-way?

    To fly one-way, consider booking your trip with Viva, which is currently one of the cheapest options available, starting at $14. Volaris flights start at $42 while deals on Alaska Airlines start at $88 one-way.

  • What are the most popular routes from Irvine to South Carolina?

    When deciding which route to take from Irvine to South Carolina consider Los Angeles Los Angeles - Charlotte Douglas, Los Angeles Los Angeles - Charleston or Los Angeles Los Angeles - Savannah/Hilton Head as they are the most popular.

  • What are the cheapest flights from Irvine to South Carolina?

    The cheapest flight price from Irvine to South Carolina is $89. On average you can expect to pay $224. The most popular route, (Los Angeles Los Angeles - Charlotte Douglas), can usually be booked for $215.

  • Can I find deals for flights from Irvine to South Carolina that include hotel bookings?

    Yes. In addition to deals on Irvine to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to South Carolina.

  • Can I find deals for business class flights from Irvine to South Carolina?

    Yes. Cheapflights offers flight deals from Irvine to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Irvine to South Carolina (average of $112). Flying from Irvine to South Carolina in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Irvine to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Honolulu flights
San Francisco to John F Kennedy Intl flights
San Francisco to Newark flights
San Francisco to LaGuardia flights
Long Beach to Honolulu flights
Los Angeles to John F Kennedy Intl flights
Burbank to Honolulu flights
Los Angeles to Seattle flights
Ontario to Honolulu flights
Los Angeles to Newark flights
San Francisco to Las Vegas flights
San Francisco to Los Angeles flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to LaGuardia flights
Los Angeles to Miami flights
San Francisco to Seattle flights
Los Angeles to San Francisco flights
San Francisco to Honolulu flights
Los Angeles to Orlando flights
San Francisco to Ontario flights
Ontario to Seattle flights
Los Angeles to Las Vegas flights
San Francisco to O'Hare Intl flights
San Francisco to Santa Ana flights
San Francisco to Dallas/Fort Worth flights
Los Angeles to O'Hare Intl flights
Ontario to San Francisco flights
Los Angeles to Kahului flights
Burbank to Las Vegas flights
San Francisco to San Diego flights
San Jose to Seattle flights
Los Angeles to Boston flights
Los Angeles to Fort Lauderdale flights
San Jose to Los Angeles flights
Los Angeles to Reagan-National flights
Los Angeles to Atlanta flights
Ontario to Dallas/Fort Worth flights
San Francisco to Sky Harbor Intl flights
San Francisco to Boston flights
Los Angeles to Denver flights
Los Angeles to Dulles Intl flights
Santa Ana to Seattle flights
San Francisco to Denver flights
Los Angeles to Sky Harbor Intl flights
Los Angeles to Baltimore flights
Los Angeles to Hobby flights
San Francisco to Miami flights
Los Angeles to Portland flights
Santa Ana to Las Vegas flights

Top 7 airlines flying from Irvine to South Carolina

Discover the top 7 airlines that operate flights from Irvine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$105Average$310FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$122Average$252FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$141Average$453FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$478FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$256Average$292FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$270Average$487FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$300Average$497FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.