$80+ Cheap flights from Denver (DEN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Apr 24 — May 11
Round-trip
1 adult, Economy
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Find cheap flights from Denver to South Carolina with Cheapflights
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Cheapest flights from Denver to South CarolinaExplore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
Explore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Wed 4/227:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/24![Frontier logo]()
$127
This Priceline deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:00 am
DEN
- CLT
Nonstop3h 25m
Frontier
Tue 5/121:00 pm
CLT
- DEN
1 stop12h 04m
Frontier
Deal found 3/24![Frontier logo]()
$134
This Gotogate deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
DEN
- CLT
1 stop7h 57m
Frontier
Wed 4/297:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/22![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Tue 5/55:20 pm
CLT
- DEN
Nonstop4h 06m
Frontier
Deal found 3/21![Frontier logo]()
$136
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Thu 5/75:20 pm
CLT
- DEN
Nonstop4h 06m
Frontier
Deal found 3/23![Frontier logo]()
$142
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:54 pm
DEN
- CLT
1 stop16h 50m
Frontier
Tue 4/217:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/20![Frontier logo]()
$143
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:59 pm
DEN
- CLT
1 stop14h 36m
Frontier
Wed 4/297:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/20![Frontier logo]()
$144
This eDestinos deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:22 pm
DEN
- CLT
1 stop25h 48m
Frontier
Wed 4/298:09 pm
CLT
- DEN
1 stop14h 12m
Frontier
Deal found 3/23![Frontier logo]()
$145
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Mon 4/273:12 pm
CLT
- DEN
1 stop20h 15m
Frontier
Deal found 3/24![Frontier logo]()
$148
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:54 pm
DEN
- MYR
1 stop18h 50m
Frontier
Sat 5/24:01 pm
MYR
- DEN
1 stop9h 08m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:20 am
DEN
- MYR
1 stop8h 24m
Frontier
Mon 4/273:09 pm
MYR
- DEN
1 stop10h 00m
Frontier
Deal found 3/20![Frontier logo]()
$185
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:59 pm
DEN
- MYR
1 stop12h 14m
Frontier
Sat 5/24:01 pm
MYR
- DEN
1 stop9h 08m
Frontier
Deal found 3/23![Frontier logo]()
$205
Best flights from Denver to South CarolinaDiscover carefully curated flight deals from Denver to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
Discover carefully curated flight deals from Denver to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:40 pm
DEN
- GSP
2 stops7h 00m
Southwest
Sat 6/61:55 pm
GSP
- DEN
1 stop11h 20m
Southwest
Deal found 3/23![Southwest logo]()
$249
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:55 am
DEN
- AGS
1 stop6h 21m
Delta
Wed 4/296:22 pm
AGS
- DEN
1 stop8h 14m
Delta
Deal found 3/24![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:45 pm
DEN
- CLT
Nonstop3h 23m
United Airlines
Mon 7/62:53 pm
CLT
- DEN
1 stop6h 52m
United Airlines
Deal found 3/21![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:41 pm
DEN
- AGS
1 stop6h 15m
American Airlines
Wed 4/294:15 pm
AGS
- DEN
2 stops9h 30m
American Airlines
Deal found 3/24![American Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:15 am
DEN
- MYR
1 stop5h 15m
Southwest
Tue 5/1211:15 am
MYR
- DEN
1 stop7h 05m
Southwest
Deal found 3/21![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:30 am
DEN
- MYR
1 stop5h 45m
Southwest
Sat 5/27:10 am
MYR
- DEN
2 stops9h 25m
Southwest
Deal found 3/20![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
DEN
- HHH
1 stop6h 24m
American Airlines
Mon 5/46:39 pm
HHH
- DEN
1 stop5h 47m
American Airlines
Deal found 3/20![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:55 am
DEN
- CLT
1 stop5h 51m
Delta
Fri 5/16:56 pm
CLT
- DEN
1 stop7h 40m
Delta
Deal found 3/21![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:13 am
DEN
- GSP
Nonstop3h 06m
United Airlines
Mon 6/295:10 pm
GSP
- DEN
1 stop8h 47m
United Airlines
Deal found 3/21![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:40 pm
DEN
- GSP
2 stops8h 05m
Southwest
Mon 6/86:50 pm
GSP
- DEN
1 stop6h 45m
Southwest
Deal found 3/25![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
DEN
- CLT
1 stop8h 26m
Delta
Mon 7/67:48 pm
CLT
- DEN
1 stop6h 46m
Delta
Deal found 3/21![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:59 pm
DEN
- MYR
1 stop9h 15m
United Airlines
Wed 4/2211:00 am
MYR
- DEN
1 stop7h 29m
United Airlines
Deal found 3/22![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:44 am
DEN
- CLT
1 stop6h 09m
Delta
Thu 7/25:30 am
CLT
- DEN
1 stop5h 05m
Delta
Deal found 3/24![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:45 am
DEN
- CLT
2 stops7h 10m
Southwest
Wed 4/296:40 am
CLT
- DEN
2 stops6h 55m
Southwest
Deal found 3/24![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:59 pm
DEN
- CHS
1 stop8h 17m
United Airlines
Tue 6/164:16 pm
CHS
- DEN
Nonstop3h 55m
United Airlines
Deal found 3/21![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:00 am
DEN
- HHH
1 stop5h 26m
American Airlines
Fri 5/152:58 pm
HHH
- DEN
2 stops10h 47m
American Airlines
Deal found 3/25![American Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:15 pm
DEN
- CLT
2 stops6h 25m
Southwest
Fri 4/176:15 am
CLT
- DEN
2 stops9h 15m
Southwest
Deal found 3/24![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:56 am
DEN
- CAE
1 stop6h 19m
Delta
Fri 6/126:01 pm
CAE
- DEN
1 stop5h 56m
Delta
Deal found 3/24![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:14 pm
DEN
- CHS
Nonstop3h 23m
United Airlines
Mon 5/47:44 pm
CHS
- DEN
1 stop7h 00m
United Airlines
Deal found 3/23![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:39 am
DEN
- HHH
1 stop5h 43m
American Airlines
Sat 4/115:04 pm
HHH
- DEN
1 stop7h 22m
American Airlines
Deal found 3/23![American Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:40 am
DEN
- CHS
2 stops9h 15m
Southwest
Mon 6/81:30 pm
CHS
- DEN
1 stop8h 35m
Southwest
Deal found 3/24![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:56 am
DEN
- CAE
1 stop6h 19m
Delta
Sat 6/131:47 pm
CAE
- DEN
1 stop6h 06m
Delta
Deal found 3/24![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:59 pm
DEN
- CHS
1 stop6h 53m
United Airlines
Mon 9/143:25 pm
CHS
- DEN
1 stop6h 14m
United Airlines
Deal found 3/21![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:40 pm
DEN
- GSP
2 stops7h 00m
Southwest
Sat 5/96:25 am
GSP
- DEN
1 stop5h 20m
Southwest
Deal found 3/22![Southwest logo]()
$334
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:55 am
DEN
- CAE
1 stop6h 19m
Delta
Sun 5/105:38 am
CAE
- DEN
1 stop5h 06m
Delta
Deal found 3/20![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
DEN
- HHH
1 stop6h 21m
United Airlines
Thu 7/23:05 pm
HHH
- DEN
1 stop7h 17m
United Airlines
Deal found 3/23![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:55 pm
DEN
- CHS
1 stop8h 25m
Southwest
Sat 5/307:15 pm
CHS
- DEN
1 stop5h 20m
Southwest
Deal found 3/22![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:55 am
DEN
- CAE
1 stop6h 19m
Delta
Mon 4/277:12 pm
CAE
- DEN
1 stop7h 24m
Delta
Deal found 3/22![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:22 am
DEN
- AGS
1 stop7h 08m
American Airlines
Sun 5/315:00 am
AGS
- DEN
1 stop6h 16m
American Airlines
Deal found 3/20![American Airlines logo]()
$505
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
DEN
- HHH
1 stop6h 21m
United Airlines
Wed 6/33:05 pm
HHH
- DEN
1 stop8h 54m
United Airlines
Deal found 3/20![United Airlines logo]()
$407
Last-minute flights from Denver to South CarolinaDiscover last-minute flight deals from Denver to South Carolina. Data last updated March 25, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to South Carolina. Data last updated March 25, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Wed 4/227:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/24![Frontier logo]()
$127
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:15 am
DEN
- GSP
1 stop5h 55m
Southwest
Sat 4/188:00 am
GSP
- DEN
1 stop9h 15m
Southwest
Deal found 3/24![Southwest logo]()
$239
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:54 pm
DEN
- CLT
1 stop16h 50m
Frontier
Tue 4/217:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/20![Frontier logo]()
$143
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:00 pm
DEN
- CLT
1 stop11h 32m
Frontier
Thu 4/236:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/24![Frontier logo]()
$151
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:59 pm
DEN
- CLT
1 stop14h 36m
Frontier
Wed 4/297:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/20![Frontier logo]()
$144
This eDestinos deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:22 pm
DEN
- CLT
1 stop25h 48m
Frontier
Wed 4/298:09 pm
CLT
- DEN
1 stop14h 12m
Frontier
Deal found 3/23![Frontier logo]()
$145
This Gotogate deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
DEN
- CLT
1 stop7h 57m
Frontier
Wed 4/297:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/22![Frontier logo]()
$135
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Mon 4/273:12 pm
CLT
- DEN
1 stop20h 15m
Frontier
Deal found 3/24![Frontier logo]()
$148
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:20 am
DEN
- MYR
1 stop8h 24m
Frontier
Mon 4/273:09 pm
MYR
- DEN
1 stop10h 00m
Frontier
Deal found 3/20![Frontier logo]()
$185
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:54 pm
DEN
- MYR
1 stop18h 50m
Frontier
Sat 5/24:01 pm
MYR
- DEN
1 stop9h 08m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:59 pm
DEN
- MYR
1 stop12h 14m
Frontier
Sat 5/24:01 pm
MYR
- DEN
1 stop9h 08m
Frontier
Deal found 3/23![Frontier logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Tue 5/55:20 pm
CLT
- DEN
Nonstop4h 06m
Frontier
Deal found 3/21![Frontier logo]()
$136
One-way flights from Denver to South CarolinaSearch for one-way flight options from Denver to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
Search for one-way flight options from Denver to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:20 am
DEN
- MYR
1 stop8h 24m
Frontier
Deal found 3/23![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:59 pm
DEN
- MYR
1 stop13h 07m
Frontier
Deal found 3/24![Frontier logo]()
$86
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
DEN
- MYR
1 stop6h 46m
Frontier
Deal found 3/20![Frontier logo]()
$105
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:59 pm
DEN
- CLT
1 stop8h 04m
Frontier
Deal found 3/22![Frontier logo]()
$105
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:56 pm
DEN
- CHS
1 stop13h 03m
Frontier
Deal found 3/24![Frontier logo]()
$106
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:25 am
DEN
- CLT
1 stop13h 11m
Frontier
Deal found 3/22![Frontier logo]()
$106
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:35 am
DEN
- CLT
1 stop6h 34m
Delta
Deal found 3/24![Delta logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:45 pm
DEN
- CLT
1 stop15h 28m
Frontier
Deal found 3/25![Frontier logo]()
$110
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:59 pm
DEN
- MYR
1 stop9h 49m
Frontier
Deal found 3/25![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:07 pm
DEN
- CLT
2 stops21h 11m
Frontier
Deal found 3/20![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:53 pm
DEN
- CLT
2 stops39h 17m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$112
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:05 pm
DEN
- CLT
2 stops7h 35m
Southwest
Deal found 3/24![Southwest logo]()
$114
Find flight deals from Denver to South Carolina
Keep the following information in mind while searching for Denver to South Carolina flight deals. Data was last updated March 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $127 (Cheapflightsfares) |
One-way from | $80 (Frontier) |
Popular in | January |
Cheapest in | August |
Average price | $453 |
Good round-trip deal | $329 or less |
Good one-way deal | $208 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Denver to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverGreenville
DEN - GSP
DENGSP
Denver Intl
Wed 6/3
12:40 pm-9:40 pm
2 stops7h 00m
Greenville
Sat 6/6
1:55 pm-11:15 pm
1 stop11h 20m
$249
DenverMyrtle Beach
DEN - MYR
DENMYR
Denver Intl
Tue 5/5
6:15 am-1:30 pm
1 stop5h 15m
Myrtle Beach Intl
Tue 5/12
11:15 am-4:20 pm
1 stop7h 05m
$271
DenverMyrtle Beach
DEN - MYR
DENMYR
Denver Intl
Sat 4/25
10:30 am-6:15 pm
1 stop5h 45m
Myrtle Beach Intl
Sat 5/2
7:10 am-2:35 pm
2 stops9h 25m
$276
DenverGreenville
DEN - GSP
DENGSP
Denver Intl
Fri 6/5
12:40 pm-10:45 pm
2 stops8h 05m
Greenville
Mon 6/8
6:50 pm-11:35 pm
1 stop6h 45m
$286
DenverAugusta
DEN - AGS
DENAGS
Denver Intl
Tue 4/21
12:55 am-9:16 am
1 stop6h 21m
Augusta Bush Field
Wed 4/29
6:22 pm-12:36 am
1 stop8h 14m
$299
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Wed 4/22
11:45 am-8:55 pm
2 stops7h 10m
Charlotte Douglas
Wed 4/29
6:40 am-11:35 am
2 stops6h 55m
$308
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Wed 4/15
1:15 pm-9:40 pm
2 stops6h 25m
Charlotte Douglas
Fri 4/17
6:15 am-1:30 pm
2 stops9h 15m
$310
Quickest round-trip
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Fri 7/3
5:45 pm-11:08 pm
Nonstop3h 23m
Charlotte Douglas
Mon 7/6
2:53 pm-7:45 pm
1 stop6h 52m
$319
DenverAugusta
DEN - AGS
DENAGS
Denver Intl
Wed 4/22
2:41 pm-10:56 pm
1 stop6h 15m
Augusta Bush Field
Wed 4/29
4:15 pm-11:45 pm
2 stops9h 30m
$323
DenverCharleston
DEN - CHS
DENCHS
Denver Intl
Fri 6/5
7:40 am-6:55 pm
2 stops9h 15m
Charleston
Mon 6/8
1:30 pm-8:05 pm
1 stop8h 35m
$325
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Denver to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Denver with our price prediction graph.
DEN-CLT
DEN-MYR
DEN-GSP
DEN-CHS
DEN-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to South Carolina
DEN-USSC
DEN-CLT
DEN-MYR
DEN-GSP
DEN-CHS
What is the cheapest month to book a flight from Denver to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Denver to South Carolina (average of $154). Flying from Denver to South Carolina in January is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to SC?
Find hourly flight availability from Denver to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2026.
A simple way to save on the total cost of your ticket is to fly from Denver to South Carolina at noon. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the afternoon.
What is the cheapest day to fly from Denver to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Denver to South Carolina. Price data was last updated on March 23, 2026.
Travelers seeking maximum savings on their Denver to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Denver to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 25, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Denver to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Denver to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Denver to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to South Carolina by cabin class
Find flights from Denver to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and South Carolina flights
Browse other Denver and South Carolina flight options. Last updated on March 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Denver to South Carolina flights
Consider these flights traveling from Denver to South Carolina.
Top 6 airlines flying from Denver to South Carolina
Discover the top 6 airlines that operate flights from Denver to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$78 | Average$252 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$139 | Average$326 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$154 | Average$334 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$188 | Average$380 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$211 | Average$432 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$231 | Average$427 | FlexibilityNo cancel fee | On-time63% |