HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$83+ Cheap flights from Denver (DEN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to South Carolina

Cheapest flights from Denver to South Carolina
Explore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:36 pm
DEN
-
CLT
Nonstop3h 12m
Frontier
Sat 3/147:43 pm
CLT
-
DEN
Nonstop4h 02m
Frontier
Deal found 1/28$117
This deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/161:36 pm
DEN
-
CLT
Nonstop3h 12m
Frontier
Mon 3/237:43 pm
CLT
-
DEN
Nonstop4h 02m
Frontier
Deal found 1/28$118
This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/131:45 pm
DEN
-
CLT
Nonstop3h 12m
Frontier
Mon 2/165:13 pm
CLT
-
DEN
Nonstop4h 05m
Frontier
Deal found 1/27$121
This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:42 pm
DEN
-
CLT
1 stop6h 57m
Frontier
Thu 3/55:13 pm
CLT
-
DEN
Nonstop4h 05m
Frontier
Deal found 1/27$126
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
DEN
-
CLT
1 stop11h 43m
Frontier
Mon 3/25:13 pm
CLT
-
DEN
Nonstop4h 05m
Frontier
Deal found 1/27$127
This Frontier deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:35 pm
DEN
-
CLT
1 stop17h 28m
Frontier
Sun 3/15:03 pm
CLT
-
DEN
Nonstop4h 05m
Frontier
Deal found 1/27$129
This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1511:05 am
DEN
-
CLT
Nonstop3h 13m
Frontier
Fri 2/207:42 pm
CLT
-
DEN
Nonstop4h 02m
Frontier
Deal found 1/27$131
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/131:45 pm
DEN
-
CLT
Nonstop3h 12m
Frontier
Wed 3/42:46 pm
CLT
-
DEN
1 stop19h 09m
Frontier
Deal found 1/28$132
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:59 pm
DEN
-
CLT
1 stop6h 14m
Frontier
Mon 2/235:13 pm
CLT
-
DEN
Nonstop4h 05m
Frontier
Deal found 1/27$137
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2311:59 pm
DEN
-
CLT
1 stop11h 52m
Frontier
Wed 2/252:46 pm
CLT
-
DEN
1 stop10h 13m
Frontier
Deal found 1/26$138
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:24 pm
DEN
-
CLT
1 stop11h 40m
Frontier
Sun 2/225:13 pm
CLT
-
DEN
Nonstop4h 05m
Frontier
Deal found 1/27$139
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:15 pm
DEN
-
CHS
2 stops25h 25m
Multiple Airlines
Sun 3/89:36 pm
CHS
-
DEN
1 stop13h 04m
Multiple Airlines
Deal found 1/28$197

Find flight deals from Denver to South Carolina

Keep the following information in mind while searching for Denver to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$117
(Cheapflightsfares)

One-way from

$83
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$456

Good round-trip deal

$329 or less

Good one-way deal

$285 or less
Provider with most accurate pricing for Denver Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Myrtle Beach Intl flights.
Search Deals
From Denver Intl to South Carolina
Search Deals
One-way flight from Denver Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Denver Intl to South Carolina.
Search Deals
Price to beat on a one-way flight from Denver Intl to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Denver to South Carolina that are best for you.

Fly from

Denver

Fly to

South Carolina

Route

Depart

Return

Price

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 3/3

5:35 pm-10:48 pm

Nonstop3h 13m

Charlotte Douglas

Wed 3/11

8:07 am-10:01 am

Nonstop3h 54m

$198

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Wed 3/4

10:10 am-3:23 pm

Nonstop3h 13m

Charlotte Douglas

Tue 3/10

4:00 pm-6:18 pm

Nonstop4h 18m

$198

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sun 3/1

11:05 am-4:18 pm

Nonstop3h 13m

Charlotte Douglas

Tue 3/3

7:00 am-9:11 am

1 stop28h 11m

$208

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sun 3/8

8:07 am-1:22 pm

Nonstop3h 15m

Charlotte Douglas

Tue 3/10

11:16 am-1:10 pm

Nonstop3h 54m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 3/6

5:28 pm-10:38 pm

Nonstop3h 10m

Charlotte Douglas

Wed 3/11

8:07 am-10:01 am

Nonstop3h 54m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sun 3/8

5:28 pm-10:38 pm

Nonstop3h 10m

Charlotte Douglas

Tue 3/10

8:07 am-10:01 am

Nonstop3h 54m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Mon 3/9

5:28 pm-10:38 pm

Nonstop3h 10m

Charlotte Douglas

Tue 3/10

4:00 pm-6:18 pm

Nonstop4h 18m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Wed 3/11

8:17 am-8:21 am

2 stops22h 04m

Charlotte Douglas

Sun 3/15

7:38 pm-11:09 pm

1 stop29h 31m

$222

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Wed 2/25

8:45 am-5:20 pm

1 stop6h 35m

Charlotte Douglas

Tue 3/3

1:35 pm-3:30 pm

Nonstop3h 55m

$228

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 2/27

4:43 pm-11:49 pm

1 stop5h 06m

Charlotte Douglas

Sat 3/7

6:59 pm-12:23 am

1 stop7h 24m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Denver to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South Carolina

What is the cheapest month to book a flight from Denver to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Denver to South Carolina (average of $140). Flying from Denver to South Carolina in January is currently the most expensive (average of $270). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SC?

Find hourly flight availability from Denver to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

A simple way to save on the total cost of your ticket is to fly from Denver to South Carolina in the afternoon. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Denver to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Denver to South Carolina. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Denver to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Denver to South Carolina

Explore weekly flight availability from Denver to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.

The most flights from DEN to USSC are scheduled on a Monday (2 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Denver to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,056 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Denver to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to South Carolina?

    Located just 18.5 mi from the city center, Denver Intl (DEN) is the airport most travelers will use when flying to South Carolina from Denver.

  • How popular is this Denver to South Carolina flight route?

    Within the past month, 4 users have taken a look at flights from Denver Intl to South Carolina.

  • How long is the flight from Denver to South Carolina?

    United Airlines, American Airlines, and Southwest can get you from Denver to South Carolina in just under 3h 13m. Your travel time can differ by up to 2h 37m. Airlines will cover a distance of 1334 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Denver to South Carolina one-way?

    $17 is the cheapest one-way deal found within the past few days, from Viva. You may also be able to find cheap deals on Volaris and Frontier, with prices starting from $45 and $79, respectively.

  • What are the most popular routes from Denver to South Carolina?

    While some choose either Denver Intl - Charleston or Denver Intl - Savannah/Hilton Head, Denver Intl - Charlotte Douglas is the most popular route from Denver to South Carolina.

  • What are the cheapest flights from Denver to South Carolina?

    Looking for the cheapest flight from Denver to South Carolina? While on average our users pay $355, our data indicates the cheapest price to be $168. The most popular route (Denver Intl - Charlotte Douglas), is priced around $128.

  • Can I find deals for flights from Denver to South Carolina that include hotel bookings?

    Yes. In addition to deals on Denver to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South Carolina.

  • Can I find deals for business class flights from Denver to South Carolina?

    Yes. Cheapflights offers flight deals from Denver to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Denver to South Carolina (average of $140). Flying from Denver to South Carolina in January is currently the most expensive (average of $270). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Las Vegas flights
Denver to Sky Harbor Intl flights
Denver to Orlando flights
Denver to LaGuardia flights
Denver to John F Kennedy Intl flights
Denver to Los Angeles flights
Denver to Dallas/Fort Worth flights
Denver to Miami flights
Denver to Newark flights
Denver to Seattle flights
Denver to Tampa flights
Denver to O'Hare Intl flights
Denver to San Francisco flights
Denver to Ontario flights
Denver to New Orleans flights
Denver to San Diego flights
Denver to Fort Lauderdale flights
Denver to Hobby flights
Denver to Atlanta flights
Denver to Honolulu flights
Denver to Boston flights
Denver to Santa Ana flights
Denver to Nashville flights
Denver to Kahului flights
Denver to Baltimore flights
Denver to George Bush Intcntl flights
Denver to Austin flights
Denver to Philadelphia flights
Denver to Dulles Intl flights
Denver to Fort Myers flights
Denver to Minneapolis flights
Denver to Reagan-National flights
Denver to Midway flights
Denver to Palm Springs flights
Denver to Salt Lake City flights
Denver to Charlotte flights
Denver to Knoxville flights
Denver to San Antonio flights
Denver to Raleigh flights
Denver to Tucson flights
Denver to San Jose flights
Denver to Detroit flights
Denver to Lihue flights
Denver to West Palm Beach flights
Denver to Charleston flights
Denver to Jacksonville flights
Denver to Burbank flights
Denver to Portland flights
Denver to Anchorage flights
Denver to Cincinnati flights

Top 6 airlines flying from Denver to South Carolina

Discover the top 6 airlines that operate flights from Denver to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$78Average$252FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$139Average$250FlexibilityNo cancel feeOn-time62%
DeltaCheapest$154Average$347FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$188Average$374FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$450FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$246Average$473FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.