HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$319+ Cheap flights from Columbia, MO (COU) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
COU — CHS
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to South Carolina

Keep the following information in mind while searching for Columbia to South Carolina flight deals. Data was last updated septiembre 17, 2025.

Round-trip from

$319
(American Airlines)
From Columbia Regional to South Carolina
Search Deals

Find flight deals from Columbia to South Carolina

Cheapest flights from Columbia to South Carolina
Explore the most affordable flight options available from Columbia to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/286:01 amCOU - HHH
2 stops8h 01mAmerican Airlines
sáb. 11/111:16 amHHH - COU
2 stops9h 03mAmerican Airlines
Deal found 9/14$319
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/306:24 amCOU - HHH
2 stops9h 23mAmerican Airlines
sáb. 10/41:57 pmHHH - COU
1 stop7h 24mAmerican Airlines
Deal found 9/15$334
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/306:33 pmCOU - CLT
1 stop4h 55mAmerican Airlines
sáb. 10/412:10 pmCLT - COU
1 stop6h 53mAmerican Airlines
Deal found 9/14$378
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/307:24 amCOU - CHS
1 stop5h 40mAmerican Airlines
sáb. 10/47:06 amCHS - COU
1 stop5h 52mAmerican Airlines
Deal found 9/14$430
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/156:01 amCOU - MYR
2 stops11h 50mAmerican Airlines
mié. 10/224:47 pmMYR - COU
1 stop6h 53mAmerican Airlines
Deal found 9/15$504
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/24:23 pmCOU - CHS
1 stop5h 08mAmerican Airlines
lun. 10/610:46 amCHS - COU
2 stops9h 33mAmerican Airlines
Deal found 9/17$514
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/302:52 pmCOU - CLT
2 stops22h 18mUnited Airlines
sáb. 10/46:00 amCLT - COU
2 stops16h 27mUnited Airlines
Deal found 9/14$557
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/14:23 pmCOU - CHS
1 stop5h 21mAmerican Airlines
dom. 10/57:06 amCHS - COU
1 stop5h 54mAmerican Airlines
Deal found 9/15$627
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/308:00 amCOU - CHS
1 stop11h 08mUnited Airlines
sáb. 10/46:02 amCHS - COU
1 stop9h 15mUnited Airlines
Deal found 9/15$737
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/152:52 pmCOU - MYR
1 stop22h 50mUnited Airlines
mié. 10/224:33 pmMYR - COU
1 stop22h 44mUnited Airlines
Deal found 9/15$753

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Columbia to South Carolina that are best for you.

Fly from

Columbia

Fly to

South Carolina

Route

Depart

Return

Price

ColumbiaHilton Head Island

COU - HHH

COUHHH

Columbia Regional

mar. 10/28

6:01 am-3:02 pm

2 stops8h 01m

Hilton Head Island

sáb. 11/1

11:16 am-7:19 pm

2 stops9h 03m

$319

ColumbiaHilton Head Island

COU - HHH

COUHHH

Columbia Regional

mar. 9/30

6:24 am-4:47 pm

2 stops9h 23m

Hilton Head Island

sáb. 10/4

1:57 pm-8:21 pm

1 stop7h 24m

$334

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

mar. 9/30

6:33 pm-12:28 am

1 stop4h 55m

Charlotte Douglas

sáb. 10/4

12:10 pm-6:03 pm

1 stop6h 53m

$378

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

mar. 9/30

7:24 am-2:04 pm

1 stop5h 40m

Charleston

sáb. 10/4

7:06 am-11:58 am

1 stop5h 52m

$430

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

mié. 10/15

6:01 am-6:51 pm

2 stops11h 50m

Myrtle Beach Intl

mié. 10/22

4:47 pm-10:40 pm

1 stop6h 53m

$504

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

jue. 10/2

4:23 pm-10:31 pm

1 stop5h 08m

Charleston

lun. 10/6

10:46 am-7:19 pm

2 stops9h 33m

$514

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

mar. 9/30

2:52 pm-2:10 pm

2 stops22h 18m

Charlotte Douglas

sáb. 10/4

6:00 am-9:27 pm

2 stops16h 27m

$557

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

mié. 10/1

4:23 pm-10:44 pm

1 stop5h 21m

Charleston

dom. 10/5

7:06 am-12:00 pm

1 stop5h 54m

$627

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

mar. 9/30

8:00 am-8:08 pm

1 stop11h 08m

Charleston

sáb. 10/4

6:02 am-2:17 pm

1 stop9h 15m

$737

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

mié. 10/15

2:52 pm-2:42 pm

1 stop22h 50m

Myrtle Beach Intl

mié. 10/22

4:33 pm-2:17 pm

1 stop22h 44m

$753

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
1
2

Best time to book a flight from Columbia to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated septiembre 17, 2025.
See what other customers who have flown with American Airlines from Columbia to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Columbia to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to South Carolina?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to South Carolina.

  • How long is the flight from Columbia, Missouri to South Carolina?

    Departing from Columbia, Missouri to South Carolina will take you 8h 01m. There are 791 mi between Columbia, Missouri and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Columbia, Missouri to South Carolina?

    When deciding which route to take from Columbia, Missouri to South Carolina consider Columbia Regional - Charleston, Columbia Regional - Hilton Head Island or Columbia Regional - Charlotte Douglas as they are the most popular.

  • Can I find deals for flights from Columbia to South Carolina that include hotel bookings?

    Yes. In addition to deals on Columbia to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to South Carolina.

  • Can I find deals for business class flights from Columbia to South Carolina?

    Yes. Cheapflights offers flight deals from Columbia to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Columbia, Missouri to South Carolina (average of $217). Flying from Columbia, Missouri to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Las Vegas flights
St. Louis to John F Kennedy Intl flights
St. Louis to LaGuardia flights
St. Louis to Newark flights
Kansas City to Las Vegas flights
St. Louis to Orlando flights
Kansas City to John F Kennedy Intl flights
Kansas City to Newark flights
Kansas City to LaGuardia flights
Kansas City to O'Hare Intl flights
St. Louis to Denver flights
Kansas City to Seattle flights
St. Louis to Dallas/Fort Worth flights
St. Louis to Sky Harbor Intl flights
Kansas City to Los Angeles flights
Kansas City to Sky Harbor Intl flights
St. Louis to Miami flights
St. Louis to Seattle flights
Kansas City to Atlanta flights
Kansas City to Orlando flights
St. Louis to Boston flights
Kansas City to Dallas/Fort Worth flights
St. Louis to Atlanta flights
Kansas City to Denver flights
Kansas City to Hobby flights
Kansas City to Miami flights
St. Louis to Los Angeles flights
St. Louis to Hobby flights
St. Louis to Dulles Intl flights
Kansas City to Boston flights
Kansas City to George Bush Intcntl flights
Kansas City to Minneapolis flights
Kansas City to Dulles Intl flights
St. Louis to San Francisco flights
St. Louis to O'Hare Intl flights
St. Louis to George Bush Intcntl flights
Kansas City to Tampa flights
St. Louis to Minneapolis flights
St. Louis to Tampa flights
St. Louis to New Orleans flights
St. Louis to Reagan-National flights
St. Louis to Baltimore flights
Kansas City to San Francisco flights
Kansas City to Portland flights
Kansas City to Fort Lauderdale flights
Kansas City to Midway flights
St. Louis to Salt Lake City flights
St. Louis to Love Field flights
St. Louis to Fort Lauderdale flights
St. Louis to Fort Myers flights

Top airline flying from Columbia to South Carolina

Discover the top airline that operate flights from Columbia to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$437Average$470FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.