HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$47+ Cheap flights from Chicago (CHI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CHS
ago. 4 — ago. 111
lun. 8/4
lun. 8/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Chicago to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Chicago to South Carolina

Keep the following information in mind while searching for Chicago to South Carolina flight deals. Data was last updated julio 30, 2025.

Round-trip from

$134
(American Airlines)

One-way from

$47
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$252

Good round-trip deal

$170 or less

Good one-way deal

$93 or less
From Chicago (CHI) to South Carolina
Search Deals
One-way flight from Chicago (CHI) to South Carolina
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to South Carolina.
Search Deals

Find flight deals from Chicago to South Carolina

Cheapest flights from Chicago to South Carolina
Explore the most affordable flight options available from Chicago to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/2410:12 amORD - MYR
Nonstop2h 01mSpirit Airlines
jue. 8/282:18 pmMYR - ORD
Nonstop2h 25mSpirit Airlines
Deal found 7/28$120
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/69:51 amORD - CLT
Nonstop2h 13mAmerican Airlines
sáb. 9/64:17 pmCLT - ORD
Nonstop2h 13mAmerican Airlines
Deal found 7/29$134
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/204:35 pmORD - CLT
1 stop6h 01mMultiple Airlines
dom. 9/2111:50 amCLT - ORD
Nonstop2h 22mMultiple Airlines
Deal found 7/29$135
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/76:06 pmORD - CLT
Nonstop2h 28mFrontier
jue. 8/1410:19 pmCLT - ORD
Nonstop2h 25mFrontier
Deal found 7/29$136
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/96:05 pmMDW - CLT
Nonstop2h 00mSouthwest
sáb. 9/135:20 pmCLT - MDW
Nonstop2h 00mSouthwest
Deal found 7/28$139
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/296:16 pmORD - CLT
Nonstop2h 21mUnited Airlines
mar. 9/26:40 amCLT - ORD
Nonstop2h 20mUnited Airlines
Deal found 7/29$141
This CheapOair deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/64:35 pmORD - CLT
1 stop6h 01mSpirit Airlines
dom. 9/73:34 pmCLT - ORD
1 stop8h 14mSpirit Airlines
Deal found 7/28$169
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/95:00 pmORD - CAE
1 stop5h 38mAmerican Airlines
sáb. 9/1310:42 amCAE - ORD
1 stop6h 08mAmerican Airlines
Deal found 7/28$179
This Booking.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/132:48 pmMDW - CLT
1 stop26h 30mFrontier
sáb. 8/169:37 pmCLT - MDW
1 stop25h 47mFrontier
Deal found 7/29$180
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/18:03 amMDW - SAV
Nonstop2h 07mAllegiant Air
lun. 8/46:00 amSAV - MDW
Nonstop2h 13mAllegiant Air
Deal found 7/29$191
This Flightnetwork deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/116:30 amORD - CAE
1 stop10h 51mSpirit Airlines
sáb. 9/2011:48 amCAE - ORD
1 stop6h 51mSpirit Airlines
Deal found 7/28$192
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/74:40 pmMDW - MYR
Nonstop1h 55mSouthwest
lun. 11/105:50 pmMYR - MDW
Nonstop2h 15mSouthwest
Deal found 7/27$197

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

Fly from

Chicago

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

dom. 8/24

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

jue. 8/28

2:18 pm-3:43 pm

Nonstop2h 25m

$120

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 9/6

9:51 am-1:04 pm

Nonstop2h 13m

Charlotte Douglas

sáb. 9/6

4:17 pm-5:30 pm

Nonstop2h 13m

$134

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 9/20

4:35 pm-11:36 pm

1 stop6h 01m

Charlotte Douglas

dom. 9/21

11:50 am-1:12 pm

Nonstop2h 22m

$135

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 8/7

6:06 pm-9:34 pm

Nonstop2h 28m

Charlotte Douglas

jue. 8/14

10:19 pm-11:44 pm

Nonstop2h 25m

$136

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mar. 9/9

6:05 pm-9:05 pm

Nonstop2h 00m

Charlotte Douglas

sáb. 9/13

5:20 pm-6:20 pm

Nonstop2h 00m

$139

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

vie. 8/29

6:16 pm-9:37 pm

Nonstop2h 21m

Charlotte Douglas

mar. 9/2

6:40 am-8:00 am

Nonstop2h 20m

$141

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 9/6

4:35 pm-11:36 pm

1 stop6h 01m

Charlotte Douglas

dom. 9/7

3:34 pm-10:48 pm

1 stop8h 14m

$169

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

mar. 9/9

5:00 pm-11:38 pm

1 stop5h 38m

Columbia Metropolitan

sáb. 9/13

10:42 am-3:50 pm

1 stop6h 08m

$179

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mié. 8/13

2:48 pm-6:18 pm

1 stop26h 30m

Charlotte Douglas

sáb. 8/16

9:37 pm-10:24 pm

1 stop25h 47m

$180

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

jue. 9/11

6:30 am-6:21 pm

1 stop10h 51m

Columbia Metropolitan

sáb. 9/20

11:48 am-5:39 pm

1 stop6h 51m

$192

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Chicago to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to South Carolina

What is the cheapest month to book a flight from Chicago to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SC?

Find hourly flight availability from Chicago to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 30, 2025.

When flying from Chicago to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago to South Carolina

Explore weekly flight availability from Chicago to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated julio 30, 2025.

The most flights from CHI to USSC are scheduled on a Monday (18 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Chicago to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated julio 30, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Chicago to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
JetBlue
7.3
Good
2,913 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Chicago to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $47. Users have also found prices from $66 and $72 on Allegiant Air and Southwest, respectively.

  • What are the most popular routes from Chicago to South Carolina?

    When deciding which route to take from Chicago to South Carolina consider Chicago O'Hare Intl - Charlotte Douglas, Chicago O'Hare Intl - Charleston or Chicago O'Hare Intl - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Chicago to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to South Carolina on time: Republic Airways (98%), Alaska Airlines (90%), American Airlines (87%).

  • What are the cheapest flights from Chicago to South Carolina?

    On average you can expect to pay $268 for a flight from Chicago to South Carolina. The cheapest flight overall is $90 while the most popular route, (Chicago O'Hare Intl - Charlotte Douglas) is currently priced at $137.

  • Can I find deals for flights from Chicago to South Carolina that include hotel bookings?

    Yes. In addition to deals on Chicago to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to South Carolina.

  • Can I find deals for business class flights from Chicago to South Carolina?

    Yes. Cheapflights offers flight deals from Chicago to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to LaGuardia flights
O'Hare Intl to Newark flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to Las Vegas flights
O'Hare Intl to Seattle flights
O'Hare Intl to Denver flights
Midway to LaGuardia flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Boston flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Orlando flights
O'Hare Intl to San Francisco flights
Midway to Newark flights
Midway to Las Vegas flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Miami flights
O'Hare Intl to Reagan-National flights
St. Louis to Las Vegas flights
O'Hare Intl to Ontario flights
O'Hare Intl to San Diego flights
O'Hare Intl to Dulles Intl flights
O'Hare Intl to Portland flights
Midway to John F Kennedy Intl flights
O'Hare Intl to Tampa flights
O'Hare Intl to Atlanta flights
O'Hare Intl to Honolulu flights
O'Hare Intl to Philadelphia flights
O'Hare Intl to Santa Ana flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Baltimore flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to Austin flights
O'Hare Intl to Nashville flights
Midway to Miami flights
Midway to Tampa flights
O'Hare Intl to Hobby flights
Midway to San Francisco flights
St. Louis to Seattle flights
O'Hare Intl to Fort Myers flights
O'Hare Intl to George Bush Intcntl flights
Midway to Denver flights
Midway to Orlando flights
O'Hare Intl to New Orleans flights
Midway to Atlanta flights
O'Hare Intl to Raleigh flights
O'Hare Intl to Charlotte flights
O'Hare Intl to Charleston flights
Midway to Seattle flights
St. Louis to LaGuardia flights

Top 5 airlines flying from Chicago to South Carolina

Discover the top 5 airlines that operate flights from Chicago to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$57Average$180FlexibilityNo cancel feeOn-time65%
DeltaCheapest$149Average$355FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$166Average$410FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$188Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$376FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.