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South Carolina

$48+ Cheap flights from Chicago (CHI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Chicago to South Carolina

Cheapest flights from Chicago to South Carolina
Explore the most affordable flight options available from Chicago to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1511:50 am
ORD
-
CLT
Nonstop2h 02m
Frontier
Fri 2/209:21 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/27$86
This Booking.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:55 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 3/910:58 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/27$87
This Frontier deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:55 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Fri 3/2010:42 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/27$92
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:31 pm
ORD
-
CLT
Nonstop2h 17m
Frontier
Mon 4/69:40 pm
CLT
-
ORD
Nonstop2h 27m
Frontier
Deal found 1/27$93
This Expedia deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:15 am
ORD
-
CLT
1 stop12h 03m
Multiple Airlines
Mon 3/910:58 pm
CLT
-
ORD
Nonstop2h 31m
Multiple Airlines
Deal found 1/29$95
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/184:43 pm
ORD
-
CLT
1 stop6h 13m
Multiple Airlines
Sun 2/223:37 pm
CLT
-
ORD
Nonstop2h 31m
Multiple Airlines
Deal found 1/28$98
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:55 pm
ORD
-
CLT
Nonstop2h 02m
Multiple Airlines
Mon 3/91:24 pm
CLT
-
ORD
1 stop6h 47m
Multiple Airlines
Deal found 1/27$100
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:05 am
ORD
-
CLT
1 stop8h 43m
Frontier
Sun 3/13:39 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/27$102
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:41 pm
ORD
-
CLT
1 stop10h 40m
Multiple Airlines
Fri 3/2010:42 pm
CLT
-
ORD
Nonstop2h 31m
Multiple Airlines
Deal found 1/27$105
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1611:53 am
ORD
-
CLT
Nonstop2h 02m
Frontier
Fri 2/209:21 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/28$106
This Super.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:24 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 2/163:40 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/29$107
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:51 pm
ORD
-
MYR
1 stop19h 04m
Spirit Airlines
Tue 3/310:09 am
MYR
-
ORD
1 stop15h 31m
Spirit Airlines
Deal found 1/27$140

Find flight deals from Chicago to South Carolina

Keep the following information in mind while searching for Chicago to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$86
(Kiwi.com)

One-way from

$48
(Orbitz)

Popular in

December

Cheapest in

August

Average price

$360

Good round-trip deal

$209 or less

Good one-way deal

$144 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
Search Deals
From Chicago (CHI) to South Carolina
Search Deals
One-way flight from Chicago (CHI) to South Carolina
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

Fly from

Chicago

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 3/7

4:43 pm-11:56 pm

1 stop6h 13m

Charlotte Douglas

Thu 3/12

1:24 pm-7:46 pm

1 stop7h 22m

$132

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 3/5

9:18 am-12:20 pm

1 stop26h 02m

Charlotte Douglas

Sun 3/8

7:00 am-9:39 am

1 stop27h 39m

$158

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 2/21

8:05 am-5:48 pm

1 stop8h 43m

Charlotte Douglas

Sat 2/28

9:28 am-3:37 pm

1 stop7h 09m

$175

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 3/7

6:45 pm-9:35 pm

Nonstop1h 50m

Charlotte Douglas

Tue 3/10

7:45 am-8:55 am

Nonstop2h 10m

$177

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 3/7

2:18 pm-5:35 pm

Nonstop2h 17m

Charlotte Douglas

Wed 3/11

10:26 am-11:55 am

Nonstop2h 29m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sun 3/8

1:00 pm-3:55 pm

Nonstop1h 55m

Charlotte Douglas

Mon 3/9

7:20 pm-8:30 pm

Nonstop2h 10m

$177

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 3/7

6:20 pm-9:31 pm

Nonstop2h 11m

Charlotte Douglas

Tue 3/10

6:15 am-7:41 am

Nonstop2h 26m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 3/10

6:15 pm-9:05 pm

Nonstop1h 50m

Charlotte Douglas

Wed 3/11

7:45 am-8:55 am

Nonstop2h 10m

$177

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 3/5

7:10 am-10:26 am

Nonstop2h 16m

Charlotte Douglas

Sat 3/7

8:00 am-9:29 am

Nonstop2h 29m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 3/7

6:45 pm-9:35 pm

Nonstop1h 50m

Charlotte Douglas

Wed 3/11

7:45 am-8:55 am

Nonstop2h 10m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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Best time to book a flight from Chicago to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to South Carolina

What is the cheapest month to book a flight from Chicago to South Carolina?

Currently, July is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $60). Flying from Chicago to South Carolina in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SC?

Find hourly flight availability from Chicago to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s typically best to fly out from Chicago to South Carolina in the evening. Doing so could potentially save you 24% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Chicago to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Chicago to South Carolina. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Chicago to South Carolina flight should consider departing on Monday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to South Carolina

Explore weekly flight availability from Chicago to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.

The most flights from CHI to USSC are scheduled on a Monday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).

How much does it cost to fly round-trip from Chicago to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Chicago to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,393 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Chicago to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to South Carolina?

    Spirit Airlines, Frontier, and Southwest can get you from Chicago to South Carolina in just under 1h 50m. Your travel time can differ by up to 6h 53m. There are 583 mi between Chicago and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago to South Carolina one-way?

    For one-way options, check prices for Volaris. According to our data, you can fly for as low as $48. Users have also found prices from $50 and $87 on Viva and Frontier, respectively.

  • What are the most popular routes from Chicago to South Carolina?

    When deciding which route to take from Chicago to South Carolina consider Chicago O'Hare Intl - Charleston, Chicago O'Hare Intl - Charlotte Douglas or Chicago O'Hare Intl - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Chicago to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to South Carolina on time: PSA Airlines (100%), Emirates (80%), Envoy Air (76%).

  • What are the cheapest flights from Chicago to South Carolina?

    On average you can expect to pay $485 for a flight from Chicago to South Carolina. The cheapest flight overall is $124 while the most popular route, (Chicago O'Hare Intl - Charleston) is currently priced at $114.

  • Can I find deals for flights from Chicago to South Carolina that include hotel bookings?

    Yes. In addition to deals on Chicago to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to South Carolina.

  • Can I find deals for business class flights from Chicago to South Carolina?

    Yes. Cheapflights offers flight deals from Chicago to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $60). Flying from Chicago to South Carolina in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to South Carolina

Discover the top 5 airlines that operate flights from Chicago to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$51Average$176FlexibilityNo cancel feeOn-time65%
DeltaCheapest$118Average$308FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$153Average$386FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$197Average$363FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$210Average$325FlexibilityNo cancel feeOn-time63%

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